A brief original contribution: The AIDS epidemic in india: A new method for estimating current human immunodeficiency virus (hiv) incidence rates

Ron Brookmeyer, Thomas Quinn, Mary Shepherd, Sanjay Mehendale, Jeanette Rodrigues, Robert Bollinger

Research output: Contribution to journalArticlepeer-review

Abstract

Human immunodeficiency virus (HIV) incidence rates in India were estimated using a new method that accounts for follow-up bias. Follow-up bias arises in epidemiologic cohort studies when the incidence rate among individuals who do and do not return for follow-up are different. The new method combines data on the prevalence of p24 antigenemia among all those initially screened together with the longitudinal follow-up data on the subset of patients who returned for follow-up. Using these methods, the current HIV incidence rate among patients attending sexually transmitted disease clinics in Pune, India, was 18.6% per year. It was found that follow-up bias can cause significant underestimation in HIV incidence rates, perhaps by as much as 60%. These incidence estimates, together with other HIV seroprevalence studies, suggest the HIV epidemic in India is growing rapidly. Am J Epidemiol 1995;142:709-13.

Original languageEnglish (US)
Pages (from-to)709-713
Number of pages5
JournalAmerican journal of epidemiology
Volume142
Issue number7
DOIs
StatePublished - Oct 1 1995

Keywords

  • Acquired immunodeficiency syndrome;
  • Bias (epidemiology);
  • Cross-sectional studies;
  • Epidemiologic methods;
  • HIV;
  • Statistics

ASJC Scopus subject areas

  • Epidemiology

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