TY - JOUR
T1 - A brief original contribution
T2 - The AIDS epidemic in india: A new method for estimating current human immunodeficiency virus (hiv) incidence rates
AU - Brookmeyer, Ron
AU - Quinn, Thomas
AU - Shepherd, Mary
AU - Mehendale, Sanjay
AU - Rodrigues, Jeanette
AU - Bollinger, Robert
PY - 1995/10/1
Y1 - 1995/10/1
N2 - Human immunodeficiency virus (HIV) incidence rates in India were estimated using a new method that accounts for follow-up bias. Follow-up bias arises in epidemiologic cohort studies when the incidence rate among individuals who do and do not return for follow-up are different. The new method combines data on the prevalence of p24 antigenemia among all those initially screened together with the longitudinal follow-up data on the subset of patients who returned for follow-up. Using these methods, the current HIV incidence rate among patients attending sexually transmitted disease clinics in Pune, India, was 18.6% per year. It was found that follow-up bias can cause significant underestimation in HIV incidence rates, perhaps by as much as 60%. These incidence estimates, together with other HIV seroprevalence studies, suggest the HIV epidemic in India is growing rapidly. Am J Epidemiol 1995;142:709-13.
AB - Human immunodeficiency virus (HIV) incidence rates in India were estimated using a new method that accounts for follow-up bias. Follow-up bias arises in epidemiologic cohort studies when the incidence rate among individuals who do and do not return for follow-up are different. The new method combines data on the prevalence of p24 antigenemia among all those initially screened together with the longitudinal follow-up data on the subset of patients who returned for follow-up. Using these methods, the current HIV incidence rate among patients attending sexually transmitted disease clinics in Pune, India, was 18.6% per year. It was found that follow-up bias can cause significant underestimation in HIV incidence rates, perhaps by as much as 60%. These incidence estimates, together with other HIV seroprevalence studies, suggest the HIV epidemic in India is growing rapidly. Am J Epidemiol 1995;142:709-13.
KW - Acquired immunodeficiency syndrome;
KW - Bias (epidemiology);
KW - Cross-sectional studies;
KW - Epidemiologic methods;
KW - HIV;
KW - Statistics
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U2 - 10.1093/oxfordjournals.aje.a117700
DO - 10.1093/oxfordjournals.aje.a117700
M3 - Article
C2 - 7572940
AN - SCOPUS:0028983090
VL - 142
SP - 709
EP - 713
JO - American Journal of Epidemiology
JF - American Journal of Epidemiology
SN - 0002-9262
IS - 7
ER -