A Bcl-xL Timer Sets Platelet Life Span

Bing Qi; J. Marie Hardwick

doi:10.1016/j.cell.2007.03.002

A Bcl-x_L Timer Sets Platelet Life Span

Bing Qi, J. Marie Hardwick

Bloomberg School of Public Health

Research output: Contribution to journal › Short survey › peer-review

21 Scopus citations

Abstract

Platelets are cell fragments lacking nuclei that play a key role in blood clotting. Using an impressive genetic screen involving ENU-mutagenesis of whole mice, Mason et al. (2007) report in this issue their identification of mutations in the antiapoptotic protein Bcl-x_L that cause accelerated death of platelets leading to platelet deficiency.

Original language	English (US)
Pages (from-to)	1035-1036
Number of pages	2
Journal	Cell
Volume	128
Issue number	6
DOIs	https://doi.org/10.1016/j.cell.2007.03.002
State	Published - Mar 23 2007

ASJC Scopus subject areas

General Biochemistry, Genetics and Molecular Biology

Access to Document

10.1016/j.cell.2007.03.002

Cite this

@article{5818e355ae784715834796f524efbd3c,

title = "A Bcl-xL Timer Sets Platelet Life Span",

abstract = "Platelets are cell fragments lacking nuclei that play a key role in blood clotting. Using an impressive genetic screen involving ENU-mutagenesis of whole mice, Mason et al. (2007) report in this issue their identification of mutations in the antiapoptotic protein Bcl-xL that cause accelerated death of platelets leading to platelet deficiency.",

author = "Bing Qi and Hardwick, {J. Marie}",

year = "2007",

month = mar,

day = "23",

doi = "10.1016/j.cell.2007.03.002",

language = "English (US)",

volume = "128",

pages = "1035--1036",

journal = "Cell",

issn = "0092-8674",

publisher = "Cell Press",

number = "6",

}

TY - JOUR

T1 - A Bcl-xL Timer Sets Platelet Life Span

AU - Qi, Bing

AU - Hardwick, J. Marie

PY - 2007/3/23

Y1 - 2007/3/23

N2 - Platelets are cell fragments lacking nuclei that play a key role in blood clotting. Using an impressive genetic screen involving ENU-mutagenesis of whole mice, Mason et al. (2007) report in this issue their identification of mutations in the antiapoptotic protein Bcl-xL that cause accelerated death of platelets leading to platelet deficiency.

AB - Platelets are cell fragments lacking nuclei that play a key role in blood clotting. Using an impressive genetic screen involving ENU-mutagenesis of whole mice, Mason et al. (2007) report in this issue their identification of mutations in the antiapoptotic protein Bcl-xL that cause accelerated death of platelets leading to platelet deficiency.

UR - http://www.scopus.com/inward/record.url?scp=33947236955&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33947236955&partnerID=8YFLogxK

U2 - 10.1016/j.cell.2007.03.002

DO - 10.1016/j.cell.2007.03.002

M3 - Short survey

C2 - 17382877

AN - SCOPUS:33947236955

SN - 0092-8674

VL - 128

SP - 1035

EP - 1036

JO - Cell

JF - Cell

IS - 6

ER -

A Bcl-x_L Timer Sets Platelet Life Span

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this