A 4-year study of the epidemiology of Vibrio cholerae in four rural areas of Bangladesh

R. Bradley Sack, A. Kasem Siddique, Ira M. Longini, Azhar Nizam, Md Yunus, M. Sirajul Islam, J. Glenn Morris, Afsar Ali, Anwar Huq, G. Balakrish Nair, Firdausi Qadri, Shah M. Faruque, David A. Sack, Rita R. Colwell

Research output: Contribution to journalArticle

Abstract

How Vibrio cholerae spreads around the world and what determines its seasonal peaks in endemic areas are not known. These features of cholera have been hypothesized to be primarily the result of environmental factors associated with aquatic habitats that can now be identified. Since 1997, fortnightly surveillance in 4 widely separated geographic locations in Bangladesh has been performed to identify patients with cholera and to collect environmental data. A total of 5670 patients (53% <5 years of age) have been studied; 14.3% had cholera (10.4% due to V. cholerae O1 El Tor, 3.8% due to O139). Both serogroups were found in all locations; outbreaks were seasonal and often occurred simultaneously. Water-use patterns showed that bathing and washing clothes in tube-well water was significantly protective in two of the sites. These data will be correlated with environmental factors, to develop a model for prediction of cholera outbreaks.

Original languageEnglish (US)
Pages (from-to)96-101
Number of pages6
JournalJournal of Infectious Diseases
Volume187
Issue number1
DOIs
StatePublished - Jan 1 2003

ASJC Scopus subject areas

  • Immunology and Allergy
  • Infectious Diseases

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    Sack, R. B., Siddique, A. K., Longini, I. M., Nizam, A., Yunus, M., Islam, M. S., Morris, J. G., Ali, A., Huq, A., Nair, G. B., Qadri, F., Faruque, S. M., Sack, D. A., & Colwell, R. R. (2003). A 4-year study of the epidemiology of Vibrio cholerae in four rural areas of Bangladesh. Journal of Infectious Diseases, 187(1), 96-101. https://doi.org/10.1086/345865