A 36-year-old patient with a multinodular lesion in the left temporal lobe

Simona Gaudino, Carmelo Lucio Sturiale, Emanuela Ruberto, Cesare Colosimo, Alessandro Olivi, Marco Gessi

Research output: Contribution to journalArticle

Abstract

A 36-year-old female patient was referred to our hospital for a six-months clinical history of episodes of right-sided focal motor seizures and absence. MRI scan showed a multi-nodular lesion in the subcortical white matter of left superior temporal gyrus. After a complete resection, the neuropathological examination revealed a lesion with marked cell vacuolation which was composed of neuroepithelial cells ranging from small to medium sized elements to larger, neuron-like cells, occasionally bi-nucleated. The neuropathological features of the lesion were compatible with the diagnosis of multinodular and vacuolating neuronal tumor (MVNT) of the CNS. MVNT is very rare, recently described entity among the large spectrum of glioneuronal tumors. It is characterized by benign clinical behavior and neurosurgical resection usually provide control of disease.

Original languageEnglish (US)
JournalJournal of Clinical Neuroscience
DOIs
StateAccepted/In press - Jan 1 2018
Externally publishedYes

Fingerprint

Temporal Lobe
Seizures
Neuroepithelial Cells
Neoplasms
Magnetic Resonance Imaging
Neurons

Keywords

  • Central nervous system
  • Epilepsy
  • Glioneuronal tumor
  • Multinodular and vacuolating neuronal tumor
  • MVNT

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology
  • Physiology (medical)

Cite this

Gaudino, S., Sturiale, C. L., Ruberto, E., Colosimo, C., Olivi, A., & Gessi, M. (Accepted/In press). A 36-year-old patient with a multinodular lesion in the left temporal lobe. Journal of Clinical Neuroscience. https://doi.org/10.1016/j.jocn.2018.01.026

A 36-year-old patient with a multinodular lesion in the left temporal lobe. / Gaudino, Simona; Sturiale, Carmelo Lucio; Ruberto, Emanuela; Colosimo, Cesare; Olivi, Alessandro; Gessi, Marco.

In: Journal of Clinical Neuroscience, 01.01.2018.

Research output: Contribution to journalArticle

Gaudino, Simona ; Sturiale, Carmelo Lucio ; Ruberto, Emanuela ; Colosimo, Cesare ; Olivi, Alessandro ; Gessi, Marco. / A 36-year-old patient with a multinodular lesion in the left temporal lobe. In: Journal of Clinical Neuroscience. 2018.
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