A 17-Year-Old Boy With Right Face Palsy, Left Leg Weakness, and Lytic Skull-Bone Lesions

Ibukunoluwa C. Akinboyo, Genevieve M. Crane, Lingling Chen, Ravit Boger

Research output: Contribution to journalArticle

Abstract

Human T-cell lymphotropic virus (HTLV), an infection that is endemic in certain parts of Asia, Africa, and South America, has been associated with malignancy and neurological deficits. Here, we describe a pediatric patient with chronic HTLV-I infection who developed complications associated with HTLV-I (ie, adult T-cell leukemia/lymphoma and HTLV-I-associated myelopathy/tropical spastic paraparesis). To our knowledge, this presentation in a child has never been described. The patient underwent a bone marrow transplant and, at the time of this writing, was in remission. This case report highlights the fact that HTLV-related complications, previously expected to occur after decades of infection, also can occur in pediatric patients, particularly those who acquired HTLV-I perinatally.

Original languageEnglish (US)
Pages (from-to)350-354
Number of pages5
JournalJournal of the Pediatric Infectious Diseases Society
Volume7
Issue number4
DOIs
StatePublished - Dec 3 2018

Fingerprint

Skull
Paralysis
Leg
T-Lymphocytes
Bone and Bones
Viruses
Adult T Cell Leukemia Lymphoma
Virus Diseases
Tropical Spastic Paraparesis
Pediatrics
South America
Spinal Cord Diseases
Bone Marrow
Transplants
Infection
Neoplasms

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Infectious Diseases

Cite this

A 17-Year-Old Boy With Right Face Palsy, Left Leg Weakness, and Lytic Skull-Bone Lesions. / Akinboyo, Ibukunoluwa C.; Crane, Genevieve M.; Chen, Lingling; Boger, Ravit.

In: Journal of the Pediatric Infectious Diseases Society, Vol. 7, No. 4, 03.12.2018, p. 350-354.

Research output: Contribution to journalArticle

Akinboyo, Ibukunoluwa C. ; Crane, Genevieve M. ; Chen, Lingling ; Boger, Ravit. / A 17-Year-Old Boy With Right Face Palsy, Left Leg Weakness, and Lytic Skull-Bone Lesions. In: Journal of the Pediatric Infectious Diseases Society. 2018 ; Vol. 7, No. 4. pp. 350-354.
@article{8b6d72789770447380eb65d3873a0043,
title = "A 17-Year-Old Boy With Right Face Palsy, Left Leg Weakness, and Lytic Skull-Bone Lesions",
abstract = "Human T-cell lymphotropic virus (HTLV), an infection that is endemic in certain parts of Asia, Africa, and South America, has been associated with malignancy and neurological deficits. Here, we describe a pediatric patient with chronic HTLV-I infection who developed complications associated with HTLV-I (ie, adult T-cell leukemia/lymphoma and HTLV-I-associated myelopathy/tropical spastic paraparesis). To our knowledge, this presentation in a child has never been described. The patient underwent a bone marrow transplant and, at the time of this writing, was in remission. This case report highlights the fact that HTLV-related complications, previously expected to occur after decades of infection, also can occur in pediatric patients, particularly those who acquired HTLV-I perinatally.",
author = "Akinboyo, {Ibukunoluwa C.} and Crane, {Genevieve M.} and Lingling Chen and Ravit Boger",
year = "2018",
month = "12",
day = "3",
doi = "10.1093/jpids/pix101",
language = "English (US)",
volume = "7",
pages = "350--354",
journal = "Journal of the Pediatric Infectious Diseases Society",
issn = "2048-7207",
publisher = "Oxford University Press",
number = "4",

}

TY - JOUR

T1 - A 17-Year-Old Boy With Right Face Palsy, Left Leg Weakness, and Lytic Skull-Bone Lesions

AU - Akinboyo, Ibukunoluwa C.

AU - Crane, Genevieve M.

AU - Chen, Lingling

AU - Boger, Ravit

PY - 2018/12/3

Y1 - 2018/12/3

N2 - Human T-cell lymphotropic virus (HTLV), an infection that is endemic in certain parts of Asia, Africa, and South America, has been associated with malignancy and neurological deficits. Here, we describe a pediatric patient with chronic HTLV-I infection who developed complications associated with HTLV-I (ie, adult T-cell leukemia/lymphoma and HTLV-I-associated myelopathy/tropical spastic paraparesis). To our knowledge, this presentation in a child has never been described. The patient underwent a bone marrow transplant and, at the time of this writing, was in remission. This case report highlights the fact that HTLV-related complications, previously expected to occur after decades of infection, also can occur in pediatric patients, particularly those who acquired HTLV-I perinatally.

AB - Human T-cell lymphotropic virus (HTLV), an infection that is endemic in certain parts of Asia, Africa, and South America, has been associated with malignancy and neurological deficits. Here, we describe a pediatric patient with chronic HTLV-I infection who developed complications associated with HTLV-I (ie, adult T-cell leukemia/lymphoma and HTLV-I-associated myelopathy/tropical spastic paraparesis). To our knowledge, this presentation in a child has never been described. The patient underwent a bone marrow transplant and, at the time of this writing, was in remission. This case report highlights the fact that HTLV-related complications, previously expected to occur after decades of infection, also can occur in pediatric patients, particularly those who acquired HTLV-I perinatally.

UR - http://www.scopus.com/inward/record.url?scp=85058750832&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85058750832&partnerID=8YFLogxK

U2 - 10.1093/jpids/pix101

DO - 10.1093/jpids/pix101

M3 - Article

VL - 7

SP - 350

EP - 354

JO - Journal of the Pediatric Infectious Diseases Society

JF - Journal of the Pediatric Infectious Diseases Society

SN - 2048-7207

IS - 4

ER -