A 1.5T MRI-conditional 12-lead electrocardiogram for MRI and intra-MR intervention

Zion Tsz Ho Tse, Charles L. Dumoulin, Gari D. Clifford, Jeff Schweitzer, Lei Qin, Julien Oster, Michael Jerosch-Herold, Raymond Y. Kwong, Gregory Michaud, William G. Stevenson, Ehud Schmidt

Research output: Contribution to journalArticle

Abstract

Purpose High-fidelity 12-lead electrocardiogram (ECG) is important for physiological monitoring of patients during MR-guided intervention and cardiac MRI. Issues in obtaining noncorrupted ECGs inside MRI include a superimposed magneto-hydro-dynamic voltage, gradient switching-induced voltages, and radiofrequency heating. These problems increase with magnetic field. The aim of this study is to develop and clinically validate a 1.5T MRI-conditional 12-lead ECG system. Methods The system was constructed with transmission lines to reduce radiofrequency induction and switching circuits to remove induced voltages. Adaptive filters, trained by 12-lead measurements outside MRI and in two orientations inside MRI, were used to remove the magneto-hydro-dynamic voltage. The system was tested on 10 (one exercising) volunteers and four arrhythmia patients. Results Switching circuits removed most imaging-induced voltages (residual noise <3% of the R-wave). Magneto-hydro-dynamic voltage removal provided intra-MRI ECGs that varied by <3.8% from those outside the MRI, preserving the true S-wave to T-wave segment. In premature ventricular contraction (PVC) patients, clean ECGs separated premature ventricular contraction and sinus rhythm beats. Measured heating was <1.5°C. The system reliably acquired multiphase (steady-state free precession) wall-motion-cine and phase-contrast-cine scans, including subjects in whom 4-lead gating failed. The system required a minimum repetition time of 4 ms to allow robust ECG processing. Conclusion High-fidelity intra-MRI 12-lead ECG is possible.

Original languageEnglish (US)
Pages (from-to)1336-1347
Number of pages12
JournalMagnetic Resonance in Medicine
Volume71
Issue number3
DOIs
Publication statusPublished - Mar 1 2014
Externally publishedYes

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Keywords

  • cardiac MRI
  • ECG
  • magneto-hydro-dynamic effect
  • MRI-guided interventions

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Cite this

Tse, Z. T. H., Dumoulin, C. L., Clifford, G. D., Schweitzer, J., Qin, L., Oster, J., ... Schmidt, E. (2014). A 1.5T MRI-conditional 12-lead electrocardiogram for MRI and intra-MR intervention. Magnetic Resonance in Medicine, 71(3), 1336-1347. https://doi.org/10.1002/mrm.24744