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  • Richard Allen
2020

A novel sleep stage scoring system: Combining expert-based features with the generalized linear model

Gunnarsdottir, K. M., Gamaldo, C., Salas, R. M., Ewen, J. B., Allen, R. P., Hu, K. & Sarma, S. V., Jan 1 2020, (Accepted/In press) In : Journal of Sleep Research. e12991.

Research output: Contribution to journalArticle

Developing a behavioral model of Restless Legs Syndrome utilizing mice with natural variances in ventral midbrain iron

Earley, C. J., Allen, R. P., Jones, B. C. & Unger, E. L., Jul 2020, In : Sleep Medicine. 71, p. 135-140 6 p.

Research output: Contribution to journalArticle

Evidence for communication of peripheral iron status to cerebrospinal fluid: Clinical implications for therapeutic strategy

Connor, J. R., Duck, K., Patton, S., Simpson, I. A., Trotti, L. M., Allen, R., Earley, C. J. & Rye, D., Apr 16 2020, In : Fluids and barriers of the CNS. 17, 1, 28.

Research output: Contribution to journalArticle

Open Access

Patient characteristics predicting responses to intravenous ferric carboxymaltose treatment of restless legs syndrome

Park, H. R., Choi, S. J., Joo, E. Y. & Allen, R. P., Nov 2020, In : Sleep Medicine. 75, p. 81-87 7 p.

Research output: Contribution to journalArticle

Pilot study: can machine learning analyses of movement discriminate between leg movements in sleep (LMS) with vs. without cortical arousals?

Jha, A., Banerjee, N., Feltch, C., Robucci, R., Earley, C. J., Lam, J. & Allen, R., Jan 1 2020, (Accepted/In press) In : Sleep and Breathing.

Research output: Contribution to journalArticle

RestEaZe: Low-power accurate sleep monitoring using a wearable multi-sensor ankle band

Bobovych, S., Sayeed, F., Banerjee, N., Robucci, R. & Allen, R. P., May 2020, In : Smart Health. 16, 100113.

Research output: Contribution to journalArticle

Resting-state connectivity and the effects of treatment in restless legs syndrome

Lee, Y. S., Ku, J., Kim, K. T., Chang, H. W., Earley, C. J., Allen, R. P. & Cho, Y. W., Mar 2020, In : Sleep Medicine. 67, p. 33-38 6 p.

Research output: Contribution to journalArticle

Assessment of change in restless legs syndrome symptoms during the acute drug-withdrawal period

Wang, A., Foster, K., Skeba, P., Hiranniramol, K., Earley, C. J. & Allen, R. P., Dec 2018, In : Sleep Medicine. 52, p. 80-87 8 p.

Research output: Contribution to journalArticle

Comorbidities, treatment, and pathophysiology in restless legs syndrome

Trenkwalder, C., Allen, R., Högl, B., Clemens, S., Patton, S., Schormair, B. & Winkelmann, J., Nov 1 2018, In : The Lancet Neurology. 17, 11, p. 994-1005 12 p.

Research output: Contribution to journalReview article

Comparison of subjective sleep quality of long-term residents at low and high altitudes: SARAHA study

Gupta, R., Ulfberg, J., Allen, R. & Goel, D., Jan 15 2018, In : Journal of Clinical Sleep Medicine. 14, 1, p. 15-21 7 p.

Research output: Contribution to journalArticle

Connecting clinical aspects to corticomotor excitability in restless legs syndrome: a TMS study

Salas, R., Kalloo, A., Earley, C. J., Celnik, P. A., Cruz, T. E., Foster, K., Cantarero, G. & Allen, R., Sep 1 2018, In : Sleep Medicine. 49, p. 105-112 8 p.

Research output: Contribution to journalArticle

Diurnal variation of default mode network in patients with restless legs syndrome

Ku, J., Lee, Y. S., Chang, H. W., Earley, C. J., Allen, R. & Cho, Y. W., Jan 1 2018, In : Sleep Medicine. 41, p. 1-8 8 p.

Research output: Contribution to journalArticle

Efficacy of ferric carboxymaltose (FCM) 500 mg dose for the treatment of Restless Legs Syndrome

Cho, Y. W., Allen, R. & Earley, C. J., Feb 1 2018, In : Sleep Medicine. 42, p. 7-12 6 p.

Research output: Contribution to journalArticle

Evidence-based and consensus clinical practice guidelines for the iron treatment of restless legs syndrome/Willis-Ekbom disease in adults and children: an IRLSSG task force report

on behalf of the & International Restless Legs Syndrome Study Group (IRLSSG), Jan 2018, In : Sleep Medicine. 41, p. 27-44 18 p.

Research output: Contribution to journalArticle

Pivotal role of adenosine neurotransmission in Restless Legs Syndrome

Ferré, S., Quiroz, C., Guitart, X., Rea, W., Seyedian, A., Moreno, E., Casadó-Anguera, V., Díaz-Ríos, M., Casadó, V., Clemens, S., Allen, R. P., Earley, C. J. & García-Borreguero, D., Jan 8 2018, In : Frontiers in Neuroscience. 11, JAN, 722.

Research output: Contribution to journalArticle

Restless legs syndrome is associated with major comorbidities in a population of Danish blood donors

Didriksen, M., Allen, R. P., Burchell, B. J., Thørner, L. W., Rigas, A. S., Di Angelantonio, E., Nielsen, M. H., Jennum, P. J., Werge, T., Erikstrup, C., Pedersen, O. B., Nielsen, K., Bruun, M. T., Burgdorf, K. S., Sørensen, E. & Ullum, H., May 2018, In : Sleep Medicine. 45, p. 124-131 8 p.

Research output: Contribution to journalArticle

TOX3 Variants Are Involved in Restless Legs Syndrome and Parkinson’s Disease with Opposite Effects

Mohtashami, S., He, Q., Ruskey, J. A., Zhou, S., Dion, P. A., Allen, R. P., Earley, C. J., Fon, E. A., Xiong, L., Dupre, N., Dauvilliers, Y., Rouleau, G. A. & Gan-Or, Z., Mar 1 2018, In : Journal of Molecular Neuroscience. 64, 3, p. 341-345 5 p.

Research output: Contribution to journalArticle

Treatment of restless legs syndrome: Evidence-based review and implications for clinical practice (Revised 2017)§

Winkelmann, J., Allen, R., Högl, B., Inoue, Y., Oertel, W., Salminen, A. V., Winkelman, J. W., Trenkwalder, C. & Sampaio, C., Jul 1 2018, In : Movement Disorders. 33, 7, p. 1077-1091 15 p.

Research output: Contribution to journalReview article

2017

Animal models of RLS phenotypes

Allen, R. P., Donelson, N. C., Jones, B. C., Li, Y., Manconi, M., Rye, D. B., Sanyal, S. & Winkelmann, J., Mar 1 2017, In : Sleep Medicine. 31, p. 23-28 6 p.

Research output: Contribution to journalReview article

Author response: Practice guideline summary: Treatment of restless legs syndrome in adults: Report of the Guideline Development, Dissemination, and Implementation Subcommittee of the American Academy of Neurology

Allen, R., Armstrong, M. J., Trenkwalder, C., Zee, P. C. & Winkelman, J. W., Jun 13 2017, In : Neurology. 88, 24, p. 2337-2338 2 p.

Research output: Contribution to journalLetter

Evaluation and management of RLS and PLMD

Allen, R., May 2 2017, Sleep Disorders Medicine: Basic Science, Technical Considerations and Clinical Aspects: Fourth Edition. Springer New York, p. 759-786 28 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

High prevalence of restless legs syndrome/Willis Ekbom Disease (RLS/WED) among people living at high altitude in the Indian Himalaya

Gupta, R., Ulfberg, J., Allen, R. & Goel, D., Jul 1 2017, In : Sleep Medicine. 35, p. 7-11 5 p.

Research output: Contribution to journalArticle

Identification of novel risk loci for restless legs syndrome in genome-wide association studies in individuals of European ancestry: a meta-analysis

23andMe Research Team, DESIR study group, 23andMe Research Team, DESIR study group, DESIR study group & DESIR study group, Nov 2017, In : The Lancet Neurology. 16, 11, p. 898-907 10 p.

Research output: Contribution to journalArticle

Intervening leg movements disrupt PLMS sequences

Hiranniramol, K., Fulda, S., Skeba, P., Earley, C. J. & Allen, R., Jan 1 2017, In : Sleep. 40, 1

Research output: Contribution to journalArticle

Introduction: Towards a better understanding of the science of RLS/WED

Garcia Borreguero, D., Winkelmann, J. & Allen, R. P., Mar 1 2017, In : Sleep Medicine. 31, p. 1-2 2 p.

Research output: Contribution to journalEditorial

Iron and restless legs syndrome: treatment, genetics and pathophysiology

Connor, J. R., Patton, S. M., Oexle, K. & Allen, R. P., Mar 1 2017, In : Sleep Medicine. 31, p. 61-70 10 p.

Research output: Contribution to journalArticle

Motor control and dyscontrol in sleep

Chokroverty, S., Bhat, S. & Allen, R., May 2 2017, Sleep Disorders Medicine: Basic Science, Technical Considerations and Clinical Aspects: Fourth Edition. Springer New York, p. 713-757 45 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Prevalence of restless legs syndrome and associated factors in an otherwise healthy population: results from the Danish Blood Donor Study

Didriksen, M., Rigas, A. S., Nielsen, M. H., Burgdorf, K. S., Sørensen, E., Ullum, H., Allen, R. P., Burchell, B. J., Di Angelantonio, E., Jennum, P., Werge, T., Erikstrup, C. & Pedersen, O. B., Aug 1 2017, In : Sleep Medicine. 36, p. 55-61 7 p.

Research output: Contribution to journalArticle

Targeting hypersensitive corticostriatal terminals in restless legs syndrome

Yepes, G., Guitart, X., Rea, W., Newman, A. H., Allen, R., Earley, C. J., Quiroz, C. & Ferré, S., Dec 1 2017, In : Annals of Neurology. 82, 6, p. 951-960 10 p.

Research output: Contribution to journalArticle

2016

Adenosine receptors as markers of brain iron deficiency: Implications for Restless Legs Syndrome

Quiroz, C., Gulyani, S., Ruiqian, W., Bonaventura, J., Cutler, R., Pearson, V., Allen, R. P., Earley, C. J., Mattson, M. P. & Ferré, S., Dec 1 2016, In : Neuropharmacology. 111, p. 160-168 9 p.

Research output: Contribution to journalArticle

Case–Control and Family-Based Association Study of Specific PTPRD Variants in Restless Legs Syndrome

Gan-Or, Z., Zhou, S., Johnson, A., Montplaisir, J. Y., Allen, R. P., Earley, C. J., Desautels, A., Dion, P. A., Xiong, L. & Rouleau, G. A., Sep 1 2016, In : Movement Disorders Clinical Practice. 3, 5, p. 460-464 5 p.

Research output: Contribution to journalArticle

Clinical efficacy of ferric carboxymaltose treatment in patients with restless legs syndrome

Cho, Y. W., Allen, R. & Earley, C. J., Sep 1 2016, In : Sleep Medicine. 25, p. 16-23 8 p.

Research output: Contribution to journalArticle

Default mode network disturbances in restless legs syndrome/Willis–Ekbom disease

Ku, J., Lee, Y. S., Chang, H. W., Earley, C. J., Allen, R. & Cho, Y. W., Jul 1 2016, In : Sleep Medicine. 23, p. 6-11 6 p.

Research output: Contribution to journalArticle

Defining morphology of periodic leg movements in sleep: an evidence-based definition of a minimum window of sustained activity

Skeba, P., Fulda, S., Hiranniramol, K., Earley, C. J. & Allen, R., Sep 21 2016, (Accepted/In press) In : Sleep and Breathing. p. 1-7 7 p.

Research output: Contribution to journalArticle

Depth and distribution of symptoms in restless legs syndrome/ Willis-Ekbom disease

Yeh, P., Ondo, W. G., Picchietti, D. L., Steven Poceta, J., Allen, R. P., Davies, C. R., Wang, L., Shi, Y., Bagai, K. & Walters, A. S., 2016, In : Journal of Clinical Sleep Medicine. 12, 12, p. 1669-1680 12 p.

Research output: Contribution to journalArticle

Effects of rotigotine on daytime symptoms in patients with primary restless legs syndrome: A randomized, placebo-controlled study

Garcia-Borreguero, D., Allen, R., Hudson, J., Dohin, E., Grieger, F., Moran, K., Schollmayer, E., Smit, R. & Winkelman, J., Jan 2 2016, In : Current Medical Research and Opinion. 32, 1, p. 77-85 9 p.

Research output: Contribution to journalArticle

Guidelines for the first-line treatment of restless legs syndrome/Willis-Ekbom disease, prevention and treatment of dopaminergic augmentation: A combined task force of the IRLSSG, EURLSSG, and the RLS-foundation

Garcia-Borreguero, D., Silber, M. H., Winkelman, J. W., Högl, B., Bainbridge, J., Buchfuhrer, M., Hadjigeorgiou, G., Inoue, Y., Manconi, M., Oertel, W., Ondo, W., Winkelmann, J. & Allen, R. P., May 1 2016, In : Sleep Medicine. 21, p. 1-11 11 p.

Research output: Contribution to journalArticle

Inter-movement interval as a primary stable measure of periodic limb movements of sleep

Skeba, P., Hiranniramol, K., Earley, C. J. & Allen, R., 2016, In : Sleep Medicine. 17, p. 138-143 6 p.

Research output: Contribution to journalArticle

Practice guideline summary: Treatment of restless legs syndrome in adults

Winkelman, J. W., Armstrong, M. J., Allen, R. P., Chaudhuri, K. R., Ondo, W., Trenkwalder, C., Zee, P. C., Gronseth, G. S., Gloss, D. & Zesiewicz, T., Dec 13 2016, In : Neurology. 87, 24, p. 2585-2593 9 p.

Research output: Contribution to journalArticle

Restless legs syndrome associated with major diseases

Trenkwalder, C., Allen, R., Högl, B., Paulus, W. & Winkelmann, J., Apr 5 2016, In : Neurology. 86, 14, p. 1336-1343 8 p.

Research output: Contribution to journalArticle

World Association of Sleep Medicine (WASM) 2016 standards for recording and scoring leg movements in polysomnograms developed by a joint task force from the International and the European Restless Legs Syndrome Study Groups (IRLSSG and EURLSSG)

Ferri, R., Fulda, S., Manconi, M., Allen, R. P., Zucconi, M., Ferini-Strambi, L., Bruni, O., Chokroverty, S., Frauscher, B., Garcia-Borreguero, D., Hirshkowitz, M., Högl, B., Inoue, Y., Jahangir, A., Marcus, C. L., Picchietti, D. L., Plazzi, G., Winkelman, J. W. & Zak, R. S., Oct 1 2016, In : Sleep Medicine. 26, p. 86-95 10 p.

Research output: Contribution to journalArticle