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2020

Adherence to tuberculosis preventive therapy measured by urine metabolite testing among people with HIV

THRio and TEKO teams, Jan 1 2020, In : AIDS (London, England). 34, 1, p. 63-71 9 p.

Research output: Contribution to journalArticle

Isoniazid
Tuberculosis
HIV
Urine
Confidence Intervals

CD4+ cell count stratification to guide tuberculosis preventive therapy for people living with HIV

Chaisson, L. H., Saraceni, V., Cohn, S., Seabrook, D., Cavalcante, S. C., Chaisson, R. E., Golub, J. E. & Durovni, B., Jan 1 2020, In : AIDS (London, England). 34, 1, p. 139-147 9 p.

Research output: Contribution to journalArticle

CD4 Lymphocyte Count
Tuberculin Test
Tuberculosis
Skin Tests
HIV
2019

Addressing critical needs in the fight to end tuberculosis with innovative tools and strategies

Hatherill, M., Chaisson, R. E. & Denkinger, C. M., Apr 1 2019, In : PLoS medicine. 16, 4, p. e1002795

Research output: Contribution to journalEditorial

Open Access
Tuberculosis
Research
Medicine
Clinical Trials

Cis-regulatory genetic variants in the CCR5 gene and natural HIV-1 control in black South Africans

Koor, G. W., Paximadis, M., Picton, A. C. P., Karatas, F., Loubser, S. A., He, W., Ahuja, S. K., Chaisson, R. E., Martinson, N., Ebrahim, O. & Tiemessen, C. T., Aug 1 2019, In : Clinical Immunology. 205, p. 16-24 9 p.

Research output: Contribution to journalArticle

Single Nucleotide Polymorphism
HIV-1
Genes
Haplotypes
Nucleic Acid Regulatory Sequences

Detection and molecular characterization of urinary tract HIV-1 populations

Mzingwane, M. L., Hunt, G., Lassauniere, R., Kalimashe, M., Bongwe, A., Ledwaba, J., Chaisson, R. E., Martinson, N., Richter, K., Bowyer, S. M. & Tiemessen, C. T., Sep 24 2019, In : Annals of Clinical Microbiology and Antimicrobials. 18, 1, 27.

Research output: Contribution to journalArticle

Open Access
Urinary Tract
HIV-1
Urine
Population
HIV

High Prevalence of Active and Latent Tuberculosis in Children and Adolescents in Tibetan Schools in India: The Zero TB Kids Initiative in Tibetan Refugee Children

Dorjee, K., Topgyal, S., Dorjee, C., Tsundue, T., Namdol, T., Tsewang, T., Nangsel, T., Lhadon, D., Choetso, T., Dawa, T., Phentok, T., Deluca, A., Tsering, L., Phunkyi, D., Sadutshang, T. D., J Bonomo, E., Paster, Z. & Chaisson, R. E., Aug 16 2019, In : Clinical Infectious Diseases. 69, 5, p. 760-768 9 p., ciy987.

Research output: Contribution to journalArticle

Open Access
Latent Tuberculosis
Refugees
India
Tuberculosis
Infection

High prevalence of rifampin-resistant tuberculosis in mountainous districts of India

Dorjee, K., Sadutshang, T. D., Rana, R. S., Topgyal, S., Phunkyi, D., Choetso, T., Chodon, T., Parmar, M., Singla, R., Paster, Z., Chaisson, R. E. & Kaushal, K. C., Jan 1 2019, (Accepted/In press) In : Indian Journal of Tuberculosis.

Research output: Contribution to journalArticle

Rifampin
India
Tuberculosis
Sputum
Multidrug-Resistant Tuberculosis

One month of rifapentine plus isoniazid to prevent HIV-related Tuberculosis

BRIEF TB/A5279 Study Team, Mar 14 2019, In : New England Journal of Medicine. 380, 11, p. 1001-1011 11 p.

Research output: Contribution to journalArticle

rifapentine
Isoniazid
Tuberculosis
HIV
Confidence Intervals

One Month of Rifapentine plus Isoniazid to Prevent HIV-Related Tuberculosis. Reply

Chaisson, R. E., Ramchandani, R. & Swindells, S., Sep 12 2019, In : The New England journal of medicine. 381, 11, p. e23

Research output: Contribution to journalLetter

rifapentine
Isoniazid
Rifampin
Tuberculosis
HIV
Malawi
Microscopy
Tuberculosis
HIV
Point-of-Care Systems
rifapentine
Clofazimine
Tuberculosis
Rifampin
Therapeutics
2018
Hepatitis Viruses
contagious disease
Hepacivirus
HIV
Education

Delay in seeking care for tuberculosis symptoms among adults newly diagnosed with HIV in rural Malawi

Ngwira, L. G., Dowdy, D. W., Khundi, M., Link Barnes, G., Nkhoma, A., Choko, A. T., Murowa, M., Chaisson, R. E., Corbett, E. L. & Fielding, K., Mar 1 2018, In : International Journal of Tuberculosis and Lung Disease. 22, 3, p. 280-286 7 p.

Research output: Contribution to journalArticle

Malawi
Tuberculosis
HIV
Health
Poverty

Exposure to latent tuberculosis treatment during pregnancy the PREVENT TB and the iadhere trials

Moro, R. N., Scott, N. A., Vernon, A., Tepper, N. K., Goldberg, S. V., Schwartzman, K., Leung, C. C., Schluger, N. W., Belknap, R. W., Chaisson, R. E., Narita, M., Machado, E. S., Lopez, M., Sanchez, J., Villarino, M. E. & Sterling, T. R., May 1 2018, In : Annals of the American Thoracic Society. 15, 5, p. 570-580 11 p.

Research output: Contribution to journalReview article

Latent Tuberculosis
Pregnancy
rifapentine
Isoniazid
Live Birth

Impact of clofazimine dosing on treatment shortening of the first-line regimen in a mouse model of tuberculosis

Ammerman, N., Swanson, R. V., Bautista, E. M., Almeida, D. V., Saini, V., Omansen, T. F., Guo, H., Chang, Y. S., Li, S. Y., Tapley, A., Tasneen, R., Tyagi, S., Betoudji, F., Moodley, C., Ngcobo, B., Pillay, L., Bester, L. A., Singh, S. D., Chaisson, R. E., Nuermberger, E. & 1 others, Grosset, J. H., Jul 1 2018, In : Antimicrobial Agents and Chemotherapy. 62, 7, e00636-18.

Research output: Contribution to journalArticle

Clofazimine
Tuberculosis
Pharmaceutical Preparations
Therapeutics
Multidrug-Resistant Tuberculosis

Poor Obstetric and Infant Outcomes in Human Immunodeficiency Virus-Infected Pregnant Women with Tuberculosis in South Africa: The Tshepiso Study

Salazar-Austin, N., Hoffmann, J., Cohn, S., Mashabela, F., Waja, Z., Lala, S., Hoffmann, C., Dooley, K. E., Chaisson, R. E. & Martinson, N., Mar 5 2018, In : Clinical Infectious Diseases. 66, 6, p. 921-929 9 p.

Research output: Contribution to journalArticle

South Africa
Obstetrics
Pregnant Women
Tuberculosis
HIV

Predictors of isoniazid preventive therapy completion among adults newly diagnosed with HIV in rural Malawi

Little, K. M., Khundi, M., Link Barnes, G., Ngwira, L. G., Nkhoma, A., Makombe, S., Corbett, E. L., Chaisson, R. E. & Dowdy, D. W., Apr 1 2018, In : International Journal of Tuberculosis and Lung Disease. 22, 4, p. 371-377 7 p.

Research output: Contribution to journalArticle

Malawi
Isoniazid
HIV
Therapeutics
Tuberculosis

The FCGR2C allele that modulated the risk of HIV-1 infection in the Thai RV144 vaccine trial is implicated in HIV-1 disease progression

Lassaunière, R., Paximadis, M., Ebrahim, O., Chaisson, R. E., Martinson, N. A. & Tiemessen, C. T., Jan 1 2018, (Accepted/In press) In : Genes and Immunity.

Research output: Contribution to journalArticle

IgG Receptors
HIV Infections
Disease Progression
HIV-1
Vaccines

Tuberculosis elimination in the Asia-Pacific region and the WHO ethics guidance

Denholm, J. T., Silva, D. S., Burhan, E. & Chaisson, R. E., Oct 31 2018, In : Tropical Medicine and Infectious Disease. 3, 4, 115.

Research output: Contribution to journalArticle

Open Access
Ethics
Tuberculosis
Public Health

Yield of household contact tracing for tuberculosis in rural South Africa

Little, K. M., Msandiwa, R., Martinson, N., Golub, J. E., Chaisson, R. E. & Dowdy, D. W., Jul 4 2018, In : BMC Infectious Diseases. 18, 1, 299.

Research output: Contribution to journalArticle

Contact Tracing
South Africa
Tuberculosis
Sputum
Africa South of the Sahara
2017

Conclusions and future directions

Chaisson, R. E. & Grosset, J. H., Mar 30 2017, Handbook of Tuberculosis. Springer International Publishing, p. 219-221 3 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

CXCR6 gene characterization in two ethnically distinct South African populations and association with viraemic disease control in HIV-1-infected black South African individuals

Picton, A. C. P., Paximadis, M., Chaisson, R. E., Martinson, N. A. & Tiemessen, C. T., Jul 1 2017, In : Clinical Immunology. 180, p. 69-79 11 p.

Research output: Contribution to journalArticle

HIV-1
Genotype
Population
Genes
Viral Load

Factors associated with non-completion of follow-up: 33-month latent tuberculous infection treatment trial

Moro, R. N., Sterling, T. R., Saukkonen, J., Vernon, A., Horsburgh, C. R., Chaisson, R. E., Hamilton, C. D., Villarino, M. E. & Goldberg, S., Mar 1 2017, In : International Journal of Tuberculosis and Lung Disease. 21, 3, p. 286-296 11 p.

Research output: Contribution to journalArticle

Infection
Ambulatory Care
Spain
Canada
Brazil

Factors associated with pulmonary impairment in HIV-infected South African adults

Gupte, A. N., Wong, M. L., Msandiwa, R., Link Barnes, G., Golub, J. E., Chaisson, R. E., Hoffmann, C. & Martinson, N. A., Sep 1 2017, In : PLoS One. 12, 9, e0184530.

Research output: Contribution to journalArticle

Obstructive Lung Diseases
Pulmonary diseases
respiratory tract diseases
lungs
HIV

Handbook of Tuberculosis

Grosset, J. H. & Chaisson, R. E., Mar 30 2017, Springer International Publishing. 221 p.

Research output: Book/ReportBook

Tuberculosis
Infectious Diseases
Lung
Clinical Trials
Education

Overview of tuberculosis

Chaisson, R. E. & Bishai, W. R., Mar 30 2017, Handbook of Tuberculosis. Springer International Publishing, p. 1-15 15 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Tuberculosis

Plasma Indoleamine 2, 3-Dioxygenase, a Biomarker for Tuberculosis in Human Immunodeficiency Virus-Infected Patients

Adu-Gyamfi, C. G., Snyman, T., Hoffmann, C., Martinson, N. A., Chaisson, R. E., George, J. A. & Suchard, M. S., Oct 1 2017, In : Clinical Infectious Diseases. 65, 8, p. 1356-1363 8 p.

Research output: Contribution to journalArticle

Indoleamine-Pyrrole 2,3,-Dioxygenase
Tuberculosis
Biomarkers
HIV
Tryptophan

Preventing tuberculosis in people with HIV—no more excuses

Chaisson, R. E. & Golub, J. E., Nov 1 2017, In : The Lancet Global Health. 5, 11, p. e1048-e1049

Research output: Contribution to journalComment/debate

Tuberculosis
HIV

Prevention of TB using rifampicin plus isoniazid reduces nevirapine concentrations in HIV-exposed infants

on behalf of the Tshepiso Study Team, Jul 1 2017, In : Journal of Antimicrobial Chemotherapy. 72, 7, p. 2028-2034 7 p., dkx112.

Research output: Contribution to journalArticle

Nevirapine
Isoniazid
Rifampin
HIV
Therapeutics

RICH2 is implicated in viraemic control of HIV-1 in black South African individuals

Paximadis, M., Ngqobe, R. N., Chaisson, R. E., Martinson, N. A. & Tiemessen, C. T., Apr 1 2017, In : Infection, Genetics and Evolution. 49, p. 78-87 10 p.

Research output: Contribution to journalArticle

human immunodeficiency virus
Human immunodeficiency virus 1
Single Nucleotide Polymorphism
HIV-1
allele
2016

A phase 2 randomized trial of a rifapentine plus moxifloxacin-based regimen for treatment of pulmonary tuberculosis

Conde, M. B., Mello, F. C. Q., Duarte, R. S., Cavalcante, S. C., Rolla, V., Dalcolmo, M., Loredo, C., Durovni, B., Armstrong, D. T., Efron, A., Link Barnes, G., Marzinke, M. A., Savic, R. M., Dooley, K. E., Cohn, S., Moulton, L. H., Chaisson, R. E. & Dorman, S. E., May 1 2016, In : PLoS One. 11, 5, e0154778.

Research output: Contribution to journalArticle

rifapentine
Pulmonary Tuberculosis
tuberculosis
lungs
isoniazid

Executive Summary: Official American Thoracic Society/Centers for Disease Control and Prevention/Infectious Diseases Society of America Clinical Practice Guidelines: Treatment of Drug-Susceptible Tuberculosis

Nahid, P., Dorman, S. E., Alipanah, N., Barry, P. M., Brozek, J. L., Cattamanchi, A., Chaisson, L. H., Chaisson, R. E., Daley, C. L., Grzemska, M., Higashi, J. M., Ho, C. S., Hopewell, P. C., Keshavjee, S. A., Lienhardt, C., Menzies, R., Merrifield, C., Narita, M., O'Brien, R., Peloquin, C. A. & 7 others, Raftery, A., Saukkonen, J., Schaaf, H. S., Sotgiu, G., Starke, J. R., Migliori, G. B. & Vernon, A., Oct 1 2016, In : Clinical Infectious Diseases. 63, 7, p. 853-867 15 p.

Research output: Contribution to journalReview article

Centers for Disease Control and Prevention (U.S.)
Practice Guidelines
Tuberculosis
Pharmaceutical Preparations
Therapeutics

Improved detection of tuberculosis and multidrug-resistant tuberculosis among tibetan refugees, India

Dierberg, K. L., Dorjee, K., Salvo, F., Cronin, W. A., Boddy, JB., Cirillo, D., Sadutshang, T. & Chaisson, R. E., Mar 1 2016, In : Emerging Infectious Diseases. 22, 3, p. 463-468 6 p.

Research output: Contribution to journalArticle

Multidrug-Resistant Tuberculosis
Refugees
India
Tuberculosis
Routine Diagnostic Tests

Official American Thoracic Society/Centers for Disease Control and Prevention/Infectious Diseases Society of America Clinical Practice Guidelines: Treatment of Drug-Susceptible Tuberculosis

Nahid, P., Dorman, S. E., Alipanah, N., Barry, P. M., Brozek, J. L., Cattamanchi, A., Chaisson, L. H., Chaisson, R. E., Daley, C. L., Grzemska, M., Higashi, J. M., Ho, C. S., Hopewell, P. C., Keshavjee, S. A., Lienhardt, C., Menzies, R., Merrifield, C., Narita, M., O'Brien, R., Peloquin, C. A. & 7 others, Raftery, A., Saukkonen, J., Schaaf, H. S., Sotgiu, G., Starke, J. R., Migliori, G. B. & Vernon, A., Oct 1 2016, In : Clinical Infectious Diseases. 63, 7, p. e147-e195

Research output: Contribution to journalReview article

Centers for Disease Control and Prevention (U.S.)
Practice Guidelines
Tuberculosis
Pharmaceutical Preparations
Therapeutics

Population Pharmacokinetics of Rifampin in Pregnant Women with Tuberculosis and HIV Coinfection in Soweto, South Africa

on behalf of the Tshepiso Study Team & Martinson, N., Mar 1 2016, In : Antimicrobial Agents and Chemotherapy. 60, 3, p. 1234-1241 8 p.

Research output: Contribution to journalArticle

Rifampin
South Africa
Coinfection
Pregnant Women
Tuberculosis

Three months of weekly rifapentine plus isoniazid for treatment of M. tuberculosis infection in HIV co-infected persons

the Tuberculosis Trials Consortium, the AIDS Clinical Trials Group for the PREVENT TB Trial (TBTC Study 26 ACTG 5259), Mar 17 2016, (Accepted/In press) In : AIDS.

Research output: Contribution to journalArticle

rifapentine
Isoniazid
HIV Infections
Tuberculosis
HIV

Treatment Failure, Drug Resistance, and CD4 T-Cell Count Decline among Postpartum Women on Antiretroviral Therapy in South Africa

Hoffmann, C., Cohn, S., Mashabela, F., Hoffmann, J. D., McIlleron, H., Denti, P., Haas, D. W., Dooley, K. E., Martinson, N. A. & Chaisson, R. E., Jan 1 2016, In : Journal of Acquired Immune Deficiency Syndromes. 71, 1, p. 31-37 7 p.

Research output: Contribution to journalArticle

CD4 Lymphocyte Count
South Africa
Treatment Failure
Drug Resistance
Postpartum Period

Treatment of non-cavitary pulmonary tuberculosis with shortened fluoroquinolone-based regimens: A meta-analysis

Alipanah, N., Cattamanchi, A., Menzies, R., Hopewell, P. C., Chaisson, R. E. & Nahid, P., Nov 1 2016, In : International Journal of Tuberculosis and Lung Disease. 20, 11, p. 1522-1528 7 p.

Research output: Contribution to journalArticle

Fluoroquinolones
Pulmonary Tuberculosis
Meta-Analysis
Ethambutol
Therapeutics