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Association of metformin use with risk of lactic acidosis across the range of kidney function: A community-based cohort study

Lazarus, B., Wu, A., Shin, J. I., Sang, Y., Alexander, G. C., Secora, A., Inker, L. A., Coresh, J., Chang, A. R. & Grams, M. E., Jul 1 2018, In : JAMA Internal Medicine. 178, 7, p. 903-910 8 p.

Research output: Contribution to journalArticle

Lactic Acidosis
Metformin
Glomerular Filtration Rate
Cohort Studies
Kidney
Coffee
Kidney Diseases
Atherosclerosis
Chronic Renal Insufficiency
Glomerular Filtration Rate

Coronary heart disease risk associated with the dyslipidaemia of chronic kidney disease

Lamprea-Montealegre, J. A., McClelland, R. L., Grams, M., Ouyang, P., Szklo, M. & De Boer, I. H., Feb 22 2018, (Accepted/In press) In : Heart.

Research output: Contribution to journalArticle

Dyslipidemias
Chronic Renal Insufficiency
Coronary Disease
Phenotype
Lipoproteins
Glomerular Filtration Rate
Atherosclerosis
Cohort Studies
Kidney Diseases
Blood Pressure

Direct Oral Anticoagulants and Risk of Acute Kidney Injury in Patients With Atrial Fibrillation

Shin, J. I., Luo, S., Alexander, G. C., Inker, L. A., Coresh, J., Chang, A. R. & Grams, M. E., Jan 16 2018, In : Journal of the American College of Cardiology. 71, 2, p. 251-252 2 p.

Research output: Contribution to journalLetter

Acute Kidney Injury
Anticoagulants
Atrial Fibrillation

Hemoglobin, albuminuria, and kidney function in cardiovascular risk: The ARIC (Atherosclerosis Risk in Communities) study

Ishigami, J., Grams, M. E., Naik, R. P., Caughey, M. C., Loehr, L. R., Uchida, S., Coresh, J. & Matsushita, K., Jan 1 2018, In : Journal of the American Heart Association. 7, 2, e007209

Research output: Contribution to journalArticle

Albuminuria
Chronic Renal Insufficiency
Anemia
Albumins
Creatinine
Kidney Diseases
Glomerular Filtration Rate
Chronic Renal Insufficiency
Cardiovascular Diseases
Renal Replacement Therapy
Polypharmacy
Chronic Renal Insufficiency
Kidney
Glomerular Filtration Rate
Hospitalization

Kidney Function in Obesity—Challenges in Indexing and Estimation

Chang, A. R., Zafar, W. & Grams, M. E., Jan 1 2018, In : Advances in Chronic Kidney Disease. 25, 1, p. 93-104 12 p.

Research output: Contribution to journalReview article

Glomerular Filtration Rate
Obesity
Kidney
Body Surface Area
Pharmaceutical Preparations

Metabolically Healthy Obesity and Risk of Kidney Function Decline

Chang, A. R., Surapaneni, A., Kirchner, H. L., Young, A., Kramer, H. J., Carey, D. J., Appel, L. J. & Grams, M. E., Jan 1 2018, (Accepted/In press) In : Obesity.

Research output: Contribution to journalArticle

Kidney
Glomerular Filtration Rate
Health Status
Weights and Measures
Metabolically Benign Obesity

Metabolomics research in chronic kidney disease

Grams, M. E., Shafi, T. & Rhee, E. P., Jun 1 2018, In : Journal of the American Society of Nephrology. 29, 6, p. 1588-1590 3 p.

Research output: Contribution to journalReview article

Metabolomics
Chronic Renal Insufficiency
Research

Predicting timing of clinical outcomes in patients with chronic kidney disease and severely decreased glomerular filtration rate

Grams, M. E. , Sang, Y. , Ballew, S. H. , Carrero, J. J. , Djurdjev, O. , Heerspink, H. J. L. , Ho, K. , Ito, S. , Marks, A. , Naimark, D. , Nash, D. M. , Navaneethan, S. D. , Sarnak, M. , Stengel, B. , Visseren, F. L. J. , Wang, A. Y. M. , Köttgen, A. , Levey, A. S. , Woodward, M. , Eckardt, K. U. & 2 others Hemmelgarn, B. & Coresh, J., Jan 1 2018, (Accepted/In press) In : Kidney International.

Research output: Contribution to journalArticle

Glomerular Filtration Rate
Chronic Renal Insufficiency
Cardiovascular Diseases
Renal Replacement Therapy
Blood Pressure
Cohort Studies
Prospective Studies
Fasting
Hemoglobins
Glucose

Risk Factors for Prognosis in Patients With Severely Decreased GFR

CKD Prognosis Consortium, Jan 1 2018, (Accepted/In press) In : Kidney International Reports.

Research output: Contribution to journalArticle

Cardiovascular Diseases
Chronic Renal Insufficiency
Renal Replacement Therapy
Glomerular Filtration Rate
Blood Pressure
Anticoagulants
Atrial Fibrillation
Warfarin
Stroke
Hemorrhage

Serum 6-Bromotryptophan Levels Identified as a Risk Factor for CKD Progression

Tin, A., Nadkarni, G., Evans, A. M., Winkler, C. A., Bottinger, E., Rebholz, C. M., Sarnak, M. J., Inker, L. A., Levey, A. S., Lipkowitz, M. S., Appel, L. J., Arking, D. E., Coresh, J. & Grams, M. E., Jul 1 2018, In : Journal of the American Society of Nephrology. 29, 7, p. 1939-1947 9 p.

Research output: Contribution to journalArticle

Ecosystem
Diet Therapy
Serum
Alleles
Confidence Intervals

Serum metabolites are associated with all-cause mortality in chronic kidney disease

Hu, J. R., Coresh, J., Inker, L. A., Levey, A. S., Zheng, Z., Rebholz, C. M., Tin, A., Appel, L. J., Chen, J., Sarnak, M. J. & Grams, M. E., Jan 1 2018, (Accepted/In press) In : Kidney International.

Research output: Contribution to journalArticle

Chronic Renal Insufficiency
Mortality
Serum
Diet Therapy
Kidney

Serum potassium and adverse outcomes across the range of kidney function: A CKD Prognosis Consortium meta-analysis

for the CKD Prognosis Consortium, May 1 2018, In : European Heart Journal. 39, 17, p. 1535-1542 8 p.

Research output: Contribution to journalArticle

Chronic Renal Insufficiency
Meta-Analysis
Potassium
Albuminuria
Kidney

Soluble urokinase-type plasminogen activator receptor in Black Americans with CKD

Luo, S., Coresh, J., Tin, A., Rebholz, C. M., Chen, T. K., Hayek, S. S., Tracy, M., Lipkowitz, M. S., Appel, L. J., Levey, A. S., Inker, L. A., Reiser, J. & Grams, M. E., Jul 6 2018, In : Clinical Journal of the American Society of Nephrology. 13, 7, p. 1013-1021 9 p.

Research output: Contribution to journalArticle

Urokinase Plasminogen Activator Receptors
Proteinuria
Kidney Diseases
Confidence Intervals
Creatinine
2017

Acute kidney injury in patients on SGLT2 inhibitors: A propensity-matched analysis

Nadkarni, G. N., Ferrandino, R., Chang, A., Surapaneni, A., Chauhan, K., Poojary, P., Saha, A., Ferket, B., Grams, M. E. & Coca, S. G., Nov 1 2017, In : Diabetes Care. 40, 11, p. 1479-1485 7 p.

Research output: Contribution to journalArticle

Sodium-Glucose Transport Proteins
Acute Kidney Injury
Kidney Diseases
Type 2 Diabetes Mellitus
Sodium-Glucose Transporter 1

Albuminuria changes are associated with subsequent risk of end-stage renal disease and mortality

Carrero, J. J., Grams, M. E., Sang, Y., Ärnlöv, J., Gasparini, A., Matsushita, K., Qureshi, A. R., Evans, M., Barany, P., Lindholm, B., Ballew, S. H., Levey, A. S., Gansevoort, R. T., Elinder, C. G. & Coresh, J., Jan 1 2017, In : Kidney International. 91, 1, p. 244-251 8 p.

Research output: Contribution to journalArticle

Albuminuria
Chronic Kidney Failure
Creatinine
Albumins
Mortality
Apolipoproteins
Kidney Diseases
African Americans
Cardiovascular Diseases
Hypertension

Association between Endothelin-1 Levels and Kidney Disease among Blacks

Rebholz, C. M., Harman, J. L., Grams, M. E., Correa, A., Shimbo, D., Coresh, J. & Young, B. A., Nov 1 2017, In : Journal of the American Society of Nephrology. 28, 11, p. 3337-3344 8 p.

Research output: Contribution to journalArticle

Kidney Diseases
Endothelin-1
Serum
Confidence Intervals
Mortality

Association Between Proton Pump Inhibitor Use and Risk of Progression of Chronic Kidney Disease

Klatte, D. C. F., Gasparini, A., Xu, H., de Deco, P., Trevisan, M., Johansson, A. L. V., Wettermark, B., Ärnlöv, J., Janmaat, C. J., Lindholm, B., Dekker, F. W., Coresh, J., Grams, M. E. & Carrero, J. J., Sep 1 2017, In : Gastroenterology. 153, 3, p. 702-710 9 p.

Research output: Contribution to journalArticle

Proton Pump Inhibitors
Chronic Renal Insufficiency
Acute Kidney Injury
Creatinine
Glomerular Filtration Rate

A tripartite complex of suPAR, APOL1 risk variants and α v β 3 integrin on podocytes mediates chronic kidney disease

Hayek, S. S. , Koh, K. H. , Grams, M. E. , Wei, C. , Ko, Y. A. , Li, J. , Samelko, B. , Lee, H. , Dande, R. R. , Lee, H. W. , Hahm, E. , Peev, V. , Tracy, M. , Tardi, N. J. , Gupta, V. , Altintas, M. M. , Garborcauskas, G. , Stojanovic, N. , Winkler, C. A. , Lipkowitz, M. S. & 11 others Tin, A., Inker, L. A., Levey, A. S., Zeier, M., Freedman, B. I., Kopp, J. B., Skorecki, K., Coresh, J., Quyyumi, A. A., Sever, S. & Reiser, J., Aug 1 2017, In : Nature Medicine. 23, 8, p. 945-956 12 p.

Research output: Contribution to journalArticle

Integrin alphaVbeta3
Urokinase Plasminogen Activator Receptors
Podocytes
Surface Plasmon Resonance
Apolipoproteins

Bariatric Surgery and Kidney-Related Outcomes

Chang, A. R., Grams, M. E. & Navaneethan, S. D., 2017, In : Kidney International Reports. 2, 2, p. 261-270 10 p.

Research output: Contribution to journalReview article

Bariatric Surgery
Kidney
Chronic Renal Insufficiency
Chronic Kidney Failure
Morbid Obesity
Neutron activation analysis
Fibroblast Growth Factors
Parathyroid Hormone
Glomerular Filtration Rate
Vitamin D
Prediabetic State
Atherosclerosis
Cohort Studies
Glucose
Fasting

Diet soda consumption and risk of incident end stage renal disease

Rebholz, C. M., Grams, M. E., Steffen, L. M., Crews, D. C., Anderson, C. A. M., Bazzano, L. A., Coresh, J. & Appel, L. J., Jan 6 2017, In : Clinical Journal of the American Society of Nephrology. 12, 1, p. 79-86 8 p.

Research output: Contribution to journalArticle

Chronic Kidney Failure
Glass
Diet
Beverages
Confidence Intervals

Epigenome-wide association studies identify DNA methylation associated with kidney function

Chu, A. Y. , Tin, A. , Schlosser, P. , Ko, Y. A. , Qiu, C. , Yao, C. , Joehanes, R. , Grams, M. E. , Liang, L. , Gluck, C. A. , Liu, C. , Coresh, J. , Hwang, S. J. , Levy, D. , Boerwinkle, E. , Pankow, J. S. , Yang, Q. , Fornage, M. , Fox, C. S. , Susztak, K. & 1 others Köttgen, A., Dec 1 2017, In : Nature Communications. 8, 1, 1286

Research output: Contribution to journalArticle

kidney diseases
methylation
kidneys
DNA Methylation
Glomerular Filtration Rate

Filtration markers as predictors of ESRD and mortality: Individual participant data meta-analysis

The CKD Biomarkers Consortium, Jan 6 2017, In : Clinical Journal of the American Society of Nephrology. 12, 1, p. 69-78 10 p.

Research output: Contribution to journalArticle

beta 2-Microglobulin
Chronic Kidney Failure
Meta-Analysis
Albuminuria
Mortality

Hyperkalemia after initiating renin-angiotensin system blockade: The Stockholm Creatinine Measurements (SCREAM) project

Bandak, G., Sang, Y., Gasparini, A., Chang, A. R., Ballew, S. H., Evans, M., Arnlov, J., Lund, L. H., Inker, L. A., Coresh, J., Carrero, J. J. & Grams, M. E., Jul 1 2017, In : Journal of the American Heart Association. 6, 7, e005428

Research output: Contribution to journalArticle

Hyperkalemia
Angiotensin Receptor Antagonists
Renin-Angiotensin System
Angiotensin-Converting Enzyme Inhibitors
Creatinine

Incidence and determinants of hyperkalemia and hypokalemia in a large healthcare system

Nilsson, E., Gasparini, A., Ärnlöv, J., Xu, H., Henriksson, K. M., Coresh, J., Grams, M. E. & Carrero, J. J., Oct 15 2017, In : International Journal of Cardiology. 245, p. 277-284 8 p.

Research output: Contribution to journalArticle

Hyperkalemia
Hypokalemia
Delivery of Health Care
Potassium
Incidence

Increases in biomarkers of hyperglycemia with age in the atherosclerosis risk in communities (aric) study

Warren, B., Rawlings, A. M., Lee, A. K., Grams, M., Coresh, J. & Selvin, E., Aug 1 2017, In : Diabetes Care. 40, 8, p. e96-e97

Research output: Contribution to journalLetter

Hyperglycemia
Atherosclerosis
Biomarkers

Lung Function and Incident Kidney Disease: The Atherosclerosis Risk in Communities (ARIC) Study

Sumida, K., Kwak, L., Grams, M. E., Yamagata, K., Punjabi, N. M., Kovesdy, C. P., Coresh, J. & Matsushita, K., 2017, (Accepted/In press) In : American Journal of Kidney Diseases.

Research output: Contribution to journalArticle

Vital Capacity
Kidney Diseases
Atherosclerosis
Lung
Chronic Renal Insufficiency

Metabolomic alterations associated with cause of CKD

Grams, M. E., Tin, A., Rebholz, C. M., Shafi, T., Köttgen, A., Perrone, R. D., Sarnak, M. J., Inker, L. A., Levey, A. S. & Coresh, J., Nov 7 2017, In : Clinical Journal of the American Society of Nephrology. 12, 11, p. 1787-1794 8 p.

Research output: Contribution to journalArticle

Metabolomics
Diet Therapy
Polycystic Kidney Diseases
Kynurenic Acid
Kidney

NFAT5 and SLC4A10 loci associate with plasma osmolality

Böger, C. A. , Gorski, M. , McMahon, G. M. , Xu, H. , Chang, Y. P. C. , Van Der Most, P. J. , Navis, G. , Nolte, I. M. , De Borst, M. H. , Zhang, W. , Lehne, B. , Loh, M. , Tan, S. T. , Boerwinkle, E. , Grams, M. E. , Sekula, P. , Li, M. , Wilmot, B. , Moon, J. G. , Scheet, P. & 86 others Cucca, F., Xiao, X., Lyytikäinen, L. P., Delgado, G., Grammer, T. B., Kleber, M. E., Sedaghat, S., Rivadeneira, F., Corre, T., Kutalik, Z., Bergmann, S., Nielson, C. M., Srikanth, P., Teumer, A., Müller-Nurasyid, M., Brockhaus, A. C., Pfeufer, A., Rathmann, W., Peters, A., Matsumoto, M., De Andrade, M., Atkinson, E. J., Robinson-Cohen, C., De Boer, I. H., Hwang, S. J., Heid, I. M., Gögele, M., Concas, M. P., Tanaka, T., Bandinelli, S., Nalls, M. A., Singleton, A., Tajuddin, S. M., Adeyemo, A., Zhou, J., Doumatey, A., McWeeney, S., Murabito, J., Franceschini, N., Flessner, M., Shlipak, M., Wilson, J. G., Chen, G., Rotimi, C. N., Zonderman, A. B., Evans, M. K., Ferrucci, L., Devuyst, O., Pirastu, M., Shuldiner, A., Hicks, A. A., Pramstaller, P. P., Kestenbaum, B., Kardia, S. L. R., Turner, S. T., Study, L. C., Briske, T. E., Gieger, C., Strauch, K., Meisinger, C., Meitinger, T., Völker, U., Nauck, M., Völzke, H., Vollenweider, P., Bochud, M., Waeber, G., Kähönen, M., Lehtimäki, T., März, W., Dehghan, A., Franco, O. H., Uitterlinden, A. G., Hofman, A., Taylor, H. A., Chambers, J. C., Kooner, J. S., Fox, C. S., Hitzemann, R., Orwoll, E. S., Pattaro, C., Schlessinger, D., Köttgen, A., Snieder, H., Parsa, A. & Cohen, D. M., Aug 1 2017, In : Journal of the American Society of Nephrology. 28, 8, p. 2311-2321 11 p.

Research output: Contribution to journalArticle

Osmolar Concentration
Meta-Analysis
Water
Sodium
Hypernatremia
Fructosamine
Chronic Renal Insufficiency
Hyperglycemia
Atherosclerosis
Biomarkers

Plasma galectin-3 levels are associated with the risk of incident chronic kidney disease

Rebholz, C. M., Selvin, E., Liang, M., Ballantyne, C. M., Hoogeveen, R. C., Aguilar, D., McEvoy, J. W., Grams, M. E. & Coresh, J., 2017, (Accepted/In press) In : Kidney International.

Research output: Contribution to journalArticle

Galectin 3
Chronic Renal Insufficiency
Glomerular Filtration Rate
Albumins
Creatinine

Potassium homeostasis in health and disease: A scientific workshop cosponsored by the National Kidney Foundation and the American Society of Hypertension

Kovesdy, C. P., Appel, L. J., Grams, M. E., Gutekunst, L., McCullough, P. A., Palmer, B. F., Pitt, B., Sica, D. A. & Townsend, R. R., 2017, (Accepted/In press) In : Journal of the American Society of Hypertension.

Research output: Contribution to journalArticle

Hyperkalemia
Potassium
Homeostasis
Chronic Renal Insufficiency
Kidney

Potassium Homeostasis in Health and Disease: A Scientific Workshop Cosponsored by the National Kidney Foundation and the American Society of Hypertension

Kovesdy, C. P., Appel, L. J., Grams, M. E., Gutekunst, L., McCullough, P. A., Palmer, B. F., Pitt, B., Sica, D. A. & Townsend, R. R., 2017, (Accepted/In press) In : American Journal of Kidney Diseases.

Research output: Contribution to journalArticle

Hyperkalemia
Potassium
Homeostasis
Chronic Renal Insufficiency
Kidney

Predicting risk of RRT in patients with CKD

Grams, M. E. & Coresh, J., Jan 6 2017, In : Clinical Journal of the American Society of Nephrology. 12, 1, p. 3-4 2 p.

Research output: Contribution to journalEditorial

Renal Replacement Therapy
Glomerular Filtration Rate
Chronic Renal Insufficiency
Chronic Kidney Failure

Proton Pump Inhibitors and Kidney Disease—GI Upset for the Nephrologist?

Toth-Manikowski, S. M. & Grams, M. E., May 1 2017, In : Kidney International Reports. 2, 3, p. 297-301 5 p.

Research output: Contribution to journalReview article

Proton Pump Inhibitors
Kidney Diseases
Observational Studies
Chronic Kidney Failure
Pharmacoepidemiology
Chronic Kidney Failure
Kidney
Serum
Confidence Intervals
Incidence

The loss of GSTM1 associates with kidney failure and heart failure

Tin, A., Scharpf, R., Estrella, M. M., Yu, B., Grove, M. L., Chang, P. P., Matsushita, K., Köttgen, A., Arking, D. E., Boerwinkle, E., Le, T. H., Coresh, J. & Grams, M. E., Nov 1 2017, In : Journal of the American Society of Nephrology. 28, 11, p. 3345-3352 8 p.

Research output: Contribution to journalArticle

Glutathione Transferase
Renal Insufficiency
Heart Failure
Exome

Thyroid function, reduced kidney function and incident chronic kidney disease in a community-based population: The Atherosclerosis Risk in Communities study

Schultheiss, U. T., Daya, N., Grams, M. E., Seufert, J., Steffes, M., Coresh, J., Selvin, E. & Köttgen, A., Nov 1 2017, In : Nephrology Dialysis Transplantation. 32, 11, p. 1874-1881 8 p.

Research output: Contribution to journalArticle

Chronic Renal Insufficiency
Atherosclerosis
Thyroid Gland
Kidney
Population
2016

Antihypertensive Medications and the Prevalence of Hyperkalemia in a Large Health System

Chang, A. R., Sang, Y., Leddy, J., Yahya, T., Kirchner, H. L., Inker, L. A., Matsushita, K., Ballew, S. H., Coresh, J. & Grams, M. E., Apr 11 2016, (Accepted/In press) In : Hypertension.

Research output: Contribution to journalArticle

Hyperkalemia
Antihypertensive Agents
Potassium
Health
Potassium Sparing Diuretics

Association between mitochondrial DNA copy number in peripheral blood and incident CKD in the atherosclerosis risk in communities study

Tin, A., Grams, M. E., Ashar, F. N., Lane, J. A., Rosenberg, A. Z., Grove, M. L., Boerwinkle, E., Selvin, E., Coresh, J., Pankratz, N. & Arking, D. E., 2016, In : Journal of the American Society of Nephrology. 27, 8, p. 2467-2473 7 p.

Research output: Contribution to journalArticle

Mitochondrial DNA
Atherosclerosis
Leukocyte Count
C-Reactive Protein
Confidence Intervals

Association of kidney disease measures with cause-specific mortality: The Korean Heart Study

Mok, Y., Matsushita, K., Sang, Y., Ballew, S. H., Grams, M., Shin, S. Y., Jee, S. H. & Coresh, J., Apr 1 2016, In : PLoS One. 11, 4, e0153429

Research output: Contribution to journalArticle

Kidney Diseases
kidney diseases
glomerular filtration rate
heart
Glomerular Filtration Rate

Associations between the serum metabolome and all-cause mortality among African Americans in the Atherosclerosis Risk in Communities (ARIC) Study

Yu, B., Heiss, G., Alexander, D., Grams, M. E. & Boerwinkle, E., Apr 1 2016, In : American Journal of Epidemiology. 183, 7, p. 650-656 7 p.

Research output: Contribution to journalArticle

Metabolome
African Americans
Atherosclerosis
Mortality
Serum