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2018

Adjudication of Transient Ischemic Attack and Stroke in the Multi-Ethnic Study of Atherosclerosis

Longstreth, W. T., Gasca, N. C., Gottesman, R. F., Pearce, J. B. & Sacco, R. L. Jan 11 2018 (Accepted/In press) In : Neuroepidemiology. p. 23-28 6 p.

Research output: Contribution to journalArticle

Transient Ischemic Attack
Atherosclerosis
Stroke
Research Personnel
Observational Studies

Association of atrial fibrillation with cognitive decline and dementia over 20 years: The ARIC-NCS (Atherosclerosis Risk in Communities Neurocognitive Study)

Chen, L. Y., Norby, F. L., Gottesman, R. F., Mosley, T. H., Soliman, E. Z., Agarwal, S. K., Loehr, L. R., Folsom, A. R., Coresh, J. & Alonso, A. Mar 20 2018 In : Journal of the American Heart Association. 7, 6, e007301

Research output: Contribution to journalArticle

Atrial Fibrillation
Cognition
Dementia
Atherosclerosis
Epidemiology

Comorbid Psychiatric Disease Is Associated With Lower Rates of Thrombolysis in Ischemic Stroke

Bongiorno, D. M., Daumit, G. L., Gottesman, R. F. & Faigle, R. Mar 1 2018 In : Stroke. 49, 3, p. 738-740 3 p.

Research output: Contribution to journalArticle

Factual Databases
Healthcare Disparities
Thrombolytic Therapy
Brain Ischemia
Mental Disorders

In Response

Dunham, A. M., Brown, C. H. & Gottesman, R. F. Jan 1 2018 In : Anesthesia and Analgesia. 126, 1, 1 p.

Research output: Contribution to journalLetter

Left ventricular hypertrophy and remodeling and risk of cognitive impairment and dementia: MESA (Multi-Ethnic Study of Atherosclerosis)

Moazzami, K., Ostovaneh, M. R., Venkatesh, B. A., Habibi, M., Yoneyama, K., Wu, C., Liu, K., Pimenta, I., Fitzpatrick, A., Shea, S., McClelland, R. L., Heckbert, S., Gottesman, R. F., Bluemke, D. A., Hughes, T. M. & Lima, J. A. C. Jan 1 2018 In : Hypertension. 71, 3, p. 429-436 8 p.

Research output: Contribution to journalArticle

Ventricular Remodeling
Left Ventricular Hypertrophy
Dementia
Atherosclerosis
Left Ventricular Function
Gastrostomy
stroke
risk factors
Stroke
gender

Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes

Neurology Working Group of the CHARGE Consortium, NINDS Stroke Genetics Network (SiGN), UK Young Lacunar DNA Study, MEGAST ROKE Consortium, AFGen Consortium, Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium, International Genomics of Blood Pressure (iGEN-BP) Consortium, INVENT Consortium, STA RNET BioBank Japan Cooperative Hospital Group, COMPASS Consortium, EPIC-CVD Consortium, EPIC-InterAct Consortium, International Stroke Genetics Consortium (ISGC) & METAST ROKE Consortium Apr 1 2018 In : Nature genetics. 50, 4, p. 524-537 14 p.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Stroke
Venous Thromboembolism
Linkage Disequilibrium
Computational Biology

Periodontal Disease, Regular Dental Care Use, and Incident Ischemic Stroke

Sen, S., Giamberardino, L. D., Moss, K., Morelli, T., Rosamond, W. D., Gottesman, R. F., Beck, J. & Offenbacher, S. Feb 1 2018 In : Stroke. 49, 2, p. 355-362 8 p.

Research output: Contribution to journalArticle

Gingivitis
Dental Care
Periodontal Diseases
Brain Ischemia
Atherosclerosis
Stroke
Quality of Life
Fatigue
Patient Reported Outcome Measures
Depression

Primary ‘dehydration’ and acute stroke: a systematic research review

Bahouth, M. N., Gottesman, R. F. & Szanton, S. L. Mar 1 2018 (Accepted/In press) In : Journal of Neurology. p. 1-15 15 p.

Research output: Contribution to journalArticle

Dehydration
Stroke
Research
Fluid Therapy
Consensus

Race Differences in Gastrostomy Tube Placement After Stroke in Majority-White, Minority-Serving, and Racially Integrated US Hospitals

Faigle, R., Cooper, L. A. & Gottesman, R. F. Feb 21 2018 (Accepted/In press) In : Dysphagia. p. 1-9 9 p.

Research output: Contribution to journalArticle

Gastrostomy
Stroke
Odds Ratio

The association of long-term exposure to particulate matter air pollution with brain MRI findings: The ARIC study

Power, M. C., Lamichhane, A. P., Liao, D., Xu, X., Jack, C. R., Gottesman, R. F., Mosley, T., Stewart, J. D., Yanosky, J. D. & Whitsel, E. A. Feb 1 2018 In : Environmental Health Perspectives. 126, 2, 027009

Research output: Contribution to journalArticle

Particulate Matter
Air Pollution
Atherosclerosis
Brain
Cerebrovascular Disorders

The association of mid-to late-life systemic inflammation with white matter structure in older adults: The Atherosclerosis Risk in Communities Study

Walker, K. A., Windham, B. G., Power, M. C., Hoogeveen, R. C., Folsom, A. R., Ballantyne, C. M., Knopman, D. S., Selvin, E., Jack, C. R. & Gottesman, R. F. Aug 1 2018 In : Neurobiology of Aging. 68, p. 26-33 8 p.

Research output: Contribution to journalArticle

Atherosclerosis
C-Reactive Protein
Inflammation
Leukoencephalopathies
Anisotropy
2017

Association between midlife vascular risk factors and estimated brain amyloid deposition

Gottesman, R. F., Schneider, A. L. C., Zhou, Y., Coresh, J., Green, E., Gupta, N., Knopman, D. S., Mintz, A., Rahmim, A., Sharrett, A. R., Wagenknecht, L. E., Wong, D. F. & Mosley, T. H. Apr 11 2017 In : JAMA - Journal of the American Medical Association. 317, 14, p. 1443-1450 8 p.

Research output: Contribution to journalArticle

Amyloid
Brain
Positron-Emission Tomography
Dementia
vascular factor

Association of midlife lipids with 20-year cognitive change: A cohort study

Power, M. C., Rawlings, A., Sharrett, A. R., Bandeen-Roche, K., Coresh, J., Ballantyne, C. M., Pokharel, Y., Michos, E. D., Penman, A., Alonso, A., Knopman, D., Mosley, T. H. & Gottesman, R. F. 2017 (Accepted/In press) In : Alzheimer's and Dementia.

Research output: Contribution to journalArticle

Hypercholesterolemia
LDL Cholesterol
Cohort Studies
Lipids
Executive Function

Association of parathyroid hormone with 20-year cognitive decline

Kim, S. M., Zhao, D., Schneider, A. L. C., Korada, S. K., Lutsey, P. L., Guallar, E., Alonso, A., Gwen Windham, B., Gottesman, R. F. & Michos, E. D. Aug 29 2017 In : Neurology. 89, 9, p. 918-926 9 p.

Research output: Contribution to journalArticle

Parathyroid Hormone
Cognition
Cognitive Dysfunction
Vitamin D
Population

Associations between midlife vascular risk factors and 25-year incident dementia in the Atherosclerosis Risk in Communities (ARIC) cohort

Gottesman, R. F., Albert, M. S., Alonso, A., Coker, L. H., Coresh, J., Davis, S. M., Deal, J. A., McKhann, G. M., Mosley, T. H., Sharrett, A. R., Schneider, A. L. C., Windham, B. G., Wruck, L. M. & Knopman, D. S. Oct 1 2017 In : JAMA Neurology. 74, 10, p. 1246-1254 9 p.

Research output: Contribution to journalArticle

Dementia
Atherosclerosis
Prehypertension
Genotype
Interviews

Asymptomatic Carotid Stenosis in Cardiac Surgery Patients: Is Less More?

Gottesman, R. F. Oct 1 2017 In : Stroke. 48, 10, p. 2650-2651 2 p.

Research output: Contribution to journalEditorial

Cardiac Surgical Procedures
Carotid Endarterectomy
Carotid Stenosis
Coronary Artery Bypass
Thoracic Surgery

Brain function and structure and risk for incident diabetes: The Atherosclerosis Risk in Communities Study

Bancks, M. P., Alonso, A., Gottesman, R. F., Mosley, T. H., Selvin, E. & Pankow, J. S. 2017 (Accepted/In press) In : Alzheimer's and Dementia.

Research output: Contribution to journalArticle

Cognition
Atherosclerosis
Brain
Magnetic Resonance Imaging
Confidence Intervals

Cerebral white matter hyperintensities on MRI and acceleration of epigenetic aging: the atherosclerosis risk in communities study

Raina, A., Zhao, X., Grove, M. L., Bressler, J., Gottesman, R. F., Guan, W., Pankow, J. S., Boerwinkle, E., Mosley, T. H. & Fornage, M. Feb 14 2017 In : Clinical Epigenetics. 9, 1, 21

Research output: Contribution to journalArticle

Epigenomics
Atherosclerosis
DNA Methylation
Magnetic Resonance Imaging
African Americans

Changes in metabolic risk factors over 10 years and their associations with late-life cognitive performance: The Multi-Ethnic Study of Atherosclerosis

Hughes, T. M., Craft, S., Baker, L. D., Espeland, M. A., Rapp, S. R., Sink, K. M., Bertoni, A. G., Burke, G. L., Gottesman, R. F., Michos, E. D., Luchsinger, J. A., Fitzpatrick, A. L. & Hayden, K. M. 2017 In : Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring. 8, p. 18-25 8 p.

Research output: Contribution to journalArticle

Atherosclerosis
Blood Pressure
Aptitude
Glucose Metabolism Disorders
Fasting

Correlates of Dementia and Mild Cognitive Impairment in Patients With Atrial Fibrillation: The Atherosclerosis Risk in Communities Neurocognitive Study (ARIC-NCS)

Alonso, A., Knopman, D. S., Gottesman, R. F., Soliman, E. Z., Shah, A. J., O'Neal, W. T., Norby, F. L., Mosley, T. H. & Chen, L. Y. Jul 24 2017 In : Journal of the American Heart Association. 6, 7

Research output: Contribution to journalArticle

Atrial Fibrillation
Dementia
Atherosclerosis
Alzheimer Disease
Odds Ratio

Defining the Relationship Between Hypertension, Cognitive Decline, and Dementia: a Review

Walker, K. A., Power, M. C. & Gottesman, R. F. Mar 1 2017 In : Current Hypertension Reports. 19, 3, 24

Research output: Contribution to journalReview article

Dementia
Hypertension
Brain
Blood Pressure
Cognition

Diabetes, prediabetes, and brain volumes and subclinical cerebrovascular disease on MRI: The atherosclerosis risk in communities neurocognitive study (ARIC-NCS)

Schneider, A. L. C., Selvin, E., Sharrett, A. R., Griswold, M., Coresh, J., Jack, C. R., Knopman, D., Mosley, T. & Gottesman, R. F. Nov 1 2017 In : Diabetes Care. 40, 11, p. 1514-1521 8 p.

Research output: Contribution to journalArticle

Cerebrovascular Disorders
Prediabetic State
Atherosclerosis
Brain
Blood Vessels

High prevalence of subclinical cerebral infarction in patients with heart failure with preserved ejection fraction

Cogswell, R. J., Norby, F. L., Gottesman, R. F., Chen, L. Y., Solomon, S., Shah, A. & Alonso, A. Oct 1 2017 In : European Journal of Heart Failure. 19, 10, p. 1303-1309 7 p.

Research output: Contribution to journalArticle

Cerebral Infarction
Heart Failure
Atrial Fibrillation
Magnetic Resonance Imaging
Atherosclerosis

How to use blood pressure guidelines for best cognitive outcomes

Gottesman, R. F. Oct 1 2017 In : JAMA Neurology. 74, 10, p. 1172-1173 2 p.

Research output: Contribution to journalEditorial

Guidelines
Blood Pressure

Incident Cardiovascular Disease Among Adults with Blood Pressure < 140/90 mm Hg

Tajeu, G. S., Booth, J. N., Colantonio, L. D., Gottesman, R. F., Howard, G., Lackland, D. T., OʼBrien, E., Oparil, S., Ravenell, J., Safford, M. M., Seals, S. R., Shimbo, D., Shea, S., Spruill, T., Tanner, R. M. & Muntner, P. Jul 1 2017 (Accepted/In press) In : Circulation.

Research output: Contribution to journalArticle

Cardiovascular Diseases
Blood Pressure
Stroke
Antihypertensive Agents
Atherosclerosis

Incident Heart Failure and Cognitive Decline: The Atherosclerosis Risk in Communities Study

Bressler, J., Knopman, D. S., Sharrett, A. R., Gottesman, R. F., Penman, A., Chang, P. P., Rosamond, W. D., Boerwinkle, E. & Mosley, T. H. Jan 1 2017 In : Journal of Cardiac Failure. 23, 1, p. 47-55 9 p.

Research output: Contribution to journalArticle

Atherosclerosis
Heart Failure
Automatic Data Processing
Vascular Diseases
African Americans
Stroke
Odds Ratio
Confidence Intervals
Sex Characteristics
Inpatients

Intracranial atherosclerosis and dementia

Dearborn, J. L., Zhang, Y., Qiao, Y., Suri, M. F. K., Liu, L., Gottesman, R. F., Rawlings, A. M., Mosley, T. H., Alonso, A., Knopman, D. S., Guallar, E. & Wasserman, B. A. Apr 18 2017 In : Neurology. 88, 16, p. 1556-1563 8 p.

Research output: Contribution to journalArticle

Intracranial Arteriosclerosis
Dementia
Confidence Intervals
Anterior Cerebral Artery
Pathologic Constriction
chronic illness
Diabetes Mellitus
Health
trend
health

Message from the Editors to our Reviewers

Gross, R. A., Worrall, B. B., Amato, A. A., Cascino, G. D., Ciccarelli, O., Corboy, J. R., Dalmau, J. O., Gottesman, R. F., Grossman, M., Millichap, J. J., Mink, J. W., Pulst, S. M. & Uitti, R. J. Jan 3 2017 In : Neurology. 88, 1, p. 2-10 9 p.

Research output: Contribution to journalEditorial

Message from the Editors to our Reviewers

Gross, R. A., Worrall, B. B., Amato, A. A., Cascino, G. D., Ciccarelli, O., Corboy, J. R., Dalmau, J. O., Gottesman, R. F., Grossman, M., Millichap, J. J., Mink, J. W., Pulst, S. M. & Uitti, R. J. Jul 4 2017 In : Neurology. 89, 1, p. 2-10 9 p.

Research output: Contribution to journalEditorial

Metabolomics and cognition in African American adults in midlife: the atherosclerosis risk in communities study

Bressler, J., Yu, B., Mosley, T. H., Knopman, D. S., Gottesman, R. F., Alonso, A., Sharrett, A. R., Wruck, L. M. & Boerwinkle, E. Jul 18 2017 In : Translational psychiatry. 7, 7, p. e1173

Research output: Contribution to journalArticle

Metabolomics
African Americans
Cognition
Dementia
Atherosclerosis

Midlife and late-life vascular risk factors and white matter microstructural integrity: The atherosclerosis risk in communities neurocognitive study

Power, M. C., Tingle, J. V., Reid, R. I., Huang, J., Sharrett, A. R., Coresh, J., Griswold, M., Kantarci, K., Jack, C. R., Knopman, D., Gottesman, R. F. & Mosley, T. H. May 1 2017 In : Journal of the American Heart Association. 6, 5, e005608

Research output: Contribution to journalArticle

Atherosclerosis
Glucose
Diffusion Tensor Imaging
vascular factor
White Matter

Midlife Systemic Inflammation, Late-Life White Matter Integrity, and Cerebral Small Vessel Disease: The Atherosclerosis Risk in Communities Study

Walker, K. A., Power, M. C., Hoogeveen, R. C., Folsom, A. R., Ballantyne, C. M., Knopman, D. S., Windham, B. G., Selvin, E., Jack, C. R. & Gottesman, R. F. Dec 1 2017 In : Stroke. 48, 12, p. 3196-3202 7 p.

Research output: Contribution to journalArticle

Cerebral Small Vessel Diseases
Cerebrovascular Disorders
Systemic Inflammatory Response Syndrome
Diffusion Tensor Imaging
Cerebral Infarction

Midlife systemic inflammatory markers are associated with late-life brain volume: The ARIC study

Walker, K. A., Hoogeveen, R. C., Folsom, A. R., Ballantyne, C. M., Knopman, D. S., Windham, B. G., Jack, C. R. & Gottesman, R. F. Nov 28 2017 In : Neurology. 89, 22, p. 2262-2270 9 p.

Research output: Contribution to journalArticle

Sex Factors
Episodic Memory
Age Factors
Factor VIII
von Willebrand Factor

Neuroimaging Correlates of Cerebral Microbleeds: The ARIC Study (Atherosclerosis Risk in Communities)

Graff-Radford, J., Simino, J., Kantarci, K., Mosley, T. H., Griswold, M. E., Windham, B. G., Sharrett, A. R., Albert, M. S., Gottesman, R. F., Jack, C. R., Vemuri, P. & Knopman, D. S. Nov 1 2017 In : Stroke. 48, 11, p. 2964-2972 9 p.

Research output: Contribution to journalArticle

Neuroimaging
Atherosclerosis
Cerebral Amyloid Angiopathy
Lacunar Stroke
Apolipoproteins E

Novel genetic loci associated with hippocampal volume

Hibar, D. P. , Adams, H. H. H. , Jahanshad, N. , Chauhan, G. , Stein, J. L. , Hofer, E. , Renteria, M. E. , Bis, J. C. , Arias-Vasquez, A. , Ikram, M. K. , Desrivières, S. , Vernooij, M. W. , Abramovic, L. , Alhusaini, S. , Amin, N. , Andersson, M. , Arfanakis, K. , Aribisala, B. S. , Armstrong, N. J. , Athanasiu, L. & 30 others Axelsson, T., Beecham, A. H., Beiser, A., Bernard, M., Blanton, S. H., Bohlken, M. M., Boks, M. P., Bralten, J., Brickman, A. M., Carmichael, O., Chakravarty, M. M., Chen, Q., Ching, C. R. K., Chouraki, V., Cuellar-Partida, G., Crivello, F., Den Braber, A., Doan, N. T., Ehrlich, S., Giddaluru, S., Goldman, A. L., Gottesman, R. F., Nyquist, P., Vaidya, D., Yanek, L. R., Becker, D. M., Calhoun, V. D., Mattay, V. S., Troncoso, J. & Weinberger, D. R. Jan 18 2017 In : Nature Communications. 8, 13624

Research output: Contribution to journalArticle

Genetic Loci
loci
Hippocampus
Genes
Episodic Memory

Perioperative low arterial oxygenation is associated with increased stroke risk in cardiac surgery

Dunham, A. M., Grega, M. A., Brown, C. H., McKhann, G. M., Baumgartner, W. A. & Gottesman, R. F. Jul 1 2017 In : Anesthesia and Analgesia. 125, 1, p. 38-43 6 p.

Research output: Contribution to journalArticle

Thoracic Surgery
Stroke
Confidence Intervals
Odds Ratio
Cardiopulmonary Bypass

Prospective associations of plasma phospholipids and mild cognitive impairment/dementia among African Americans in the ARIC Neurocognitive Study

Li, D., Misialek, J. R., Boerwinkle, E., Gottesman, R. F., Sharrett, A. R., Mosley, T. H., Coresh, J., Wruck, L. M., Knopman, D. S. & Alonso, A. 2017 In : Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring. 6, p. 1-10 10 p.

Research output: Contribution to journalArticle

African Americans
Dementia
Phospholipids
Area Under Curve
Cognitive Dysfunction
Minority Health
Healthcare Disparities
Asian Americans
Cerebral Hemorrhage
Palliative Care

Racial differences in prevalence and risk for intracranial atherosclerosis in a us community-based population

Qiao, Y., Suri, F. K., Zhang, Y., Liu, L., Gottesman, R., Alonso, A., Guallar, E. & Wasserman, B. A. Dec 1 2017 In : JAMA Cardiology. 2, 12, p. 1341-1348 8 p.

Research output: Contribution to journalArticle

Intracranial Arteriosclerosis
Population
Hypertension
Hyperlipidemias
Smoking

Sleep characteristics and risk of dementia and Alzheimer's disease: The Atherosclerosis Risk in Communities Study

Lutsey, P. L., Misialek, J. R., Mosley, T. H., Gottesman, R. F., Punjabi, N. M., Shahar, E., MacLehose, R., Ogilvie, R. P., Knopman, D. & Alonso, A. 2017 (Accepted/In press) In : Alzheimer's and Dementia.

Research output: Contribution to journalArticle

Dementia
Atherosclerosis
Alzheimer Disease
Sleep
Obstructive Sleep Apnea

The BIOCARD Index: A Summary Measure to Predict Onset of Mild Cognitive Impairment

Sacktor, N., Soldan, A., Grega, M., Farrington, L., Cai, Q., Wang, M. C., Gottesman, R. F., Turner, R. S., Albert, M. & the BIOCARD Research Team Apr 7 2017 (Accepted/In press) In : Alzheimer Disease and Associated Disorders.

Research output: Contribution to journalArticle

Cerebrovascular Disorders
Cognitive Dysfunction
Neuroimaging
Brain Injuries
Physical Examination
2016
Cerebrovascular Disorders
Testosterone
Atherosclerosis
Stroke
Body Mass Index

Dehydration Status is Associated with More Severe Hemispatial Neglect after Stroke

Bahouth, M. N., Bahrainwala, Z., Hillis, A. E. & Gottesman, R. F. Nov 1 2016 In : Neurologist. 21, 6, p. 101-105 5 p.

Research output: Contribution to journalArticle

Perceptual Disorders
Dehydration
Stroke
Creatinine
Blood Urea Nitrogen

Dementia after intracerebral hemorrhage

Gottesman, R. F. Aug 1 2016 In : JAMA Neurology. 73, 8, p. 916-917 2 p.

Research output: Contribution to journalEditorial

Cerebral Hemorrhage
Dementia

Factor Structure of the ARIC-NCS Neuropsychological Battery: An Evaluation of Invariance Across Vascular Factors and Demographic Characteristics

Rawlings, A. M., Bandeen-Roche, K., Gross, A. L., Gottesman, R. F., Coker, L. H., Penman, A. D., Sharrett, A. R. & Mosley, T. H. Mar 10 2016 (Accepted/In press) In : Psychological Assessment.

Research output: Contribution to journalArticle

Statistical Factor Analysis
Atherosclerosis
Sex Education
Neuropsychological Tests
Demography

Genetic variants associated with risk of Alzheimer's disease contribute to cognitive change in midlife: The Atherosclerosis Risk in Communities Study

Bressler, J., Mosley, T. H., Penman, A., Gottesman, R. F., Windham, B. G., Knopman, D. S., Wruck, L. M. & Boerwinkle, E. 2016 (Accepted/In press) In : American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics.

Research output: Contribution to journalArticle

Atherosclerosis
Alzheimer Disease
Alleles
African Americans
Cognition