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2018

Blue light cystoscopy for the diagnosis of bladder cancer: Results from the US prospective multicenter registry

Blue Light Cystoscopy with Cysview Registry Group Jan 1 2018 (Accepted/In press) In : Urologic Oncology: Seminars and Original Investigations.

Research output: Contribution to journalArticle

Cystoscopy
Urinary Bladder Neoplasms
Registries
Light
Carcinoma in Situ

Characterization of Urothelial Cancer Circulating Tumor Cells with a Novel Selection-Free Method

Chalfin, H. J., Kates, M., van der Toom, E. E., Glavaris, S., Verdone, J. E., Hahn, N. M., Pienta, K. J., Bivalacqua, T. J. & Gorin, M. A. Jan 1 2018 (Accepted/In press) In : Urology.

Research output: Contribution to journalArticle

Circulating Neoplastic Cells
Urinary Bladder Neoplasms
Neoplasms
Carcinoma
Muscles

Characterization of voiding function and structural bladder changes in a rat model of neurogenic underactive bladder disease

Weyne, E., Dewulf, K., Deruyer, Y., Rietjens, R., Everaerts, W., Bivalacqua, T. J., De Ridder, D., Van der Aa, F. & Albersen, M. Jan 1 2018 (Accepted/In press) In : Neurourology and Urodynamics.

Research output: Contribution to journalArticle

Urinary Bladder Diseases
Neurogenic Urinary Bladder
Urinary Bladder
Osteopontin
Smooth Muscle Myocytes
Carcinoma
Drug Therapy
Control Groups
Biopsy
Education

Concomitant CIS on TURBT does not impact oncological outcomes in patients treated with neoadjuvant or induction chemotherapy followed by radical cystectomy

Vasdev, N. , Zargar, H. , Noël, J. P. , Veeratterapillay, R. , Fairey, A. S. , Mertens, L. S. , Dinney, C. P. , Mir, M. C. , Krabbe, L. M. , Cookson, M. S. , Jacobsen, N. E. , Gandhi, N. M. , Griffin, J. , Montgomery, J. S. , Yu, E. Y. , Xylinas, E. , Campain, N. J. , Kassouf, W. , Dall’Era, M. A. , Seah, J. A. & 21 others Ercole, C. E., Horenblas, S., Sridhar, S. S., McGrath, J. S., Aning, J., Shariat, S. F., Wright, J. L., Morgan, T. M., Bivalacqua, T. J., North, S., Barocas, D. A., Lotan, Y., Grivas, P., Stephenson, A. J., Shah, J. B., van Rhijn, B. W., Daneshmand, S., Spiess, P. E., Holzbeierlein, J. M., Thorpe, A. & Black, P. C. Jun 7 2018 (Accepted/In press) In : World Journal of Urology. p. 1-8 8 p.

Research output: Contribution to journalArticle

Induction Chemotherapy
Cystectomy
Carcinoma in Situ
Urinary Bladder Neoplasms
Drug Therapy

Efficacy and Safety of Blue Light Flexible Cystoscopy with Hexaminolevulinate in the Surveillance of Bladder Cancer: A Phase III, Comparative, Multicenter Study

Flexible Blue Light Study Group Collaborators May 1 2018 In : Journal of Urology. 199, 5, p. 1158-1165 8 p.

Research output: Contribution to journalArticle

Cystoscopy
Urinary Bladder Neoplasms
Multicenter Studies
Safety
Light

Galanin Administration Partially Restores Erectile Function After Cavernous Nerve Injury and Mediates Endogenous Nitrergic Nerve Outgrowth In Vitro

Weyne, E., Hannan, J. L., Gevaert, T., Soebadi, Y., Matsui, H., Castiglione, F., van Renterghem, K., De Ridder, D., Van der Aa, F., Bivalacqua, T. J. & Albersen, M. Jan 1 2018 (Accepted/In press) In : Journal of Sexual Medicine.

Research output: Contribution to journalArticle

Nitrergic Neurons
Galanin
Erectile Dysfunction
Galanin Receptors
Wounds and Injuries

Immunotherapy with Checkpoint Blockade in the Treatment of Urothelial Carcinoma

Siefker-Radtke, A. O., Apolo, A. B., Bivalacqua, T. J., Spiess, P. E. & Black, P. C. May 1 2018 In : Journal of Urology. 199, 5, p. 1129-1142 14 p.

Research output: Contribution to journalReview article

Immunotherapy
Carcinoma
Therapeutics
Allergy and Immunology
PubMed

Molecular Profile of Priapism Associated with Low Nitric Oxide Bioavailability

La Favor, J. D., Fu, Z., Venkatraman, V., Bivalacqua, T. J., Van Eyk, J. E. & Burnett, A. L. Mar 2 2018 In : Journal of Proteome Research. 17, 3, p. 1031-1040 10 p.

Research output: Contribution to journalArticle

Priapism
Penis
Proteomics
Biological Availability
Mass Spectrometry

Neoadjuvant Dose Dense MVAC versus Gemcitabine and Cisplatin in Patients with cT3-4aN0M0 Bladder Cancer Treated with Radical Cystectomy

Collaborators Jun 1 2018 In : Journal of Urology. 199, 6, p. 1452-1458 7 p.

Research output: Contribution to journalArticle

gemcitabine
Vinblastine
Cystectomy
Urinary Bladder Neoplasms
Methotrexate

Non-invasive detection of urothelial cancer through the analysis of driver gene mutations and aneuploidy

Springer, S. U. , Chen, C. H. , Del Carmen Rodriguez Pena, M. , Li, L. , Douville, C. , Wang, Y. , Cohen, J. D. , Taheri, D. , Silliman, N. , Schaefer, J. , Ptak, J. , Dobbyn, L. , Papoli, M. , Kinde, I. , Afsari, B. , Tregnago, A. C. , Bezerra, S. M. , Vandenbussche, C. , Fujita, K. , Ertoy, D. & 20 others Cunha, I. W., Yu, L., Bivalacqua, T. J., Grollman, A. P., Diaz, L. A., Karchin, R., Danilova, L., Huang, C. Y., Shun, C. T., Turesky, R. J., Yun, B. H., Rosenquist, T. A., Pu, Y. S., Hruban, R. H., Tomasetti, C., Papadopoulos, N., Kinzler, K. W., Vogelstein, B., Dickman, K. G. & Netto, G. J. Mar 20 2018 In : eLife. 7, e32143

Research output: Contribution to journalArticle

Aneuploidy
Urinary Bladder Neoplasms
Cell Biology
Mutation
Neoplasm DNA

Organoid culture of bladder cancer cells

Yoshida, T., Singh, A. K., Bishai, W. R., McConkey, D. J. & Bivalacqua, T. J. May 1 2018 In : Investigative and Clinical Urology. 59, 3, p. 149-151 3 p.

Research output: Contribution to journalEditorial

Organoids
Urinary Bladder Neoplasms
Positron-Emission Tomography
Prostatic Neoplasms
Tomography
Surgical Pathology
Lymph Nodes

Recommendations for follow-up of muscle-invasive bladder cancer patients: A consensus by the international bladder cancer network

Zuiverloon, T. C. M., van Kessel, K. E. M., Bivalacqua, T. J., Boormans, J. L., Ecke, T. H., Grivas, P. D., Kiltie, A. E., Liedberg, F., Necchi, A., van Rhijn, B. W., Roghmann, F., Sanchez-Carbayo, M., Schmitz-Dräger, B. J., Wezel, F. & Kamat, A. M. Jan 1 2018 (Accepted/In press) In : Urologic Oncology: Seminars and Original Investigations.

Research output: Contribution to journalArticle

Urinary Bladder Neoplasms
Muscles
Guidelines
Cell Biology
Physicians

Surgical excision of a large, verrucous, scrotal mass in a patient with HSV-2 and HIV-1 co-infection

Luderowski, E., Bivalacqua, T. & Sopko, N. Sep 1 2018 In : Urology Case Reports. 20, p. 1-2 2 p.

Research output: Contribution to journalArticle

Herpes Genitalis
Human Herpesvirus 2
Acyclovir
Serology
Coinfection

Surgical Factors Associated With Male and Female Sexual Dysfunction After Radical Cystectomy: What Do We Know and How Can We Improve Outcomes?

Pederzoli, F., Campbell, J. D., Matsui, H., Sopko, N. A. & Bivalacqua, T. J. Jan 1 2018 (Accepted/In press) In : Sexual Medicine Reviews.

Research output: Contribution to journalArticle

Cystectomy
Erectile Dysfunction
Anatomy
Post and Core Technique
Therapeutics

Three-dimensional organoid culture reveals involvement of Wnt/β-catenin pathway in proliferation of bladder cancer cells

Yoshida, T., Sopko, N. A., Kates, M., Liu, X., Joice, G., McConkey, D. J. & Bivalacqua, T. J. Jan 1 2018 In : Oncotarget. 9, 13, p. 11060-11070 11 p.

Research output: Contribution to journalArticle

Organoids
beta Catenin
Urinary Bladder Neoplasms
Neoplasms
Cellular Spheroids
Paris
Cell Biology
Urology
Terminology
Urine
2017

Additive effects of the Rho kinase inhibitor Y-27632 and vardenafil on relaxation of the corpus cavernosum tissue of patients with erectile dysfunction and clinical phosphodiesterase type 5 inhibitor failure

Uvin, P., Albersen, M., Bollen, I., Falter, M., Weyne, E., Linsen, L., Tinel, H., Sandner, P., Bivalacqua, T. J., De Ridder, D. J. M. K., Van der Aa, F., Brône, B. & Van Renterghem, K. Feb 1 2017 In : BJU International. 119, 2, p. 325-332 8 p.

Research output: Contribution to journalArticle

Phosphodiesterase 5 Inhibitors
rho-Associated Kinases
Erectile Dysfunction
Dimethyl Sulfoxide
Smooth Muscle

Analysis of Hospital Readmissions After Prosthetic Urologic Surgery in the United States: Nationally Representative Estimates of Causes, Costs, and Predictive Factors

Pederzoli, F., Chappidi, M. R., Collica, S., Kates, M., Joice, G. A., Sopko, N. A., Montorsi, F., Salonia, A. & Bivalacqua, T. J. Aug 1 2017 In : Journal of Sexual Medicine. 14, 8, p. 1059-1065 7 p.

Research output: Contribution to journalArticle

Artificial Urinary Sphincter
Patient Readmission
Penile Prosthesis
Costs and Cost Analysis
Hospital Costs

An Empirical vs Risk-Based Approach Algorithm to Intracavernosal Injection Therapy: A Prospective Study

Bernie, H. L., Segal, R., Le, B., Burnett, A. & Bivalacqua, T. J. Mar 1 2017 In : Sexual Medicine. 5, 1, p. e31-e36

Research output: Contribution to journalArticle

Erectile Dysfunction
Prospective Studies
Injections
Prostaglandins E
Papaverine

A phase II trial of dovitinib in BCG-unresponsive urothelial carcinoma with FGFR3 mutations or overexpression: Hoosier Cancer Research Network trial HCRN 12-157

Hahn, N. M. , Bivalacqua, T. J. , Ross, A. E. , Netto, G. J. , Baras, A. , Park, J. C. , Chapman, C. , Masterson, T. A. , Koch, M. O. , Bihrle, R. , Foster, R. S. , Gardner, T. A. , Cheng, L. , Jones, D. R. , McElyea, K. , Sandusky, G. E. , Breen, T. , Liu, Z. , Albany, C. , Moore, M. L. & 9 others Loman, R. L., Reed, A., Turner, S. A., De Abreu, F. B., Gallagher, T., Tsongalis, G. J., Plimack, E. R., Greenberg, R. E. & Geynisman, D. M. Jun 15 2017 In : Clinical Cancer Research. 23, 12, p. 3003-3011 9 p.

Research output: Contribution to journalArticle

Mycobacterium bovis
Carcinoma
Mutation
Research
Neoplasms

Biomanufacturing Seamless Tubular and Hollow Collagen Scaffolds with Unique Design Features and Biomechanical Properties

Singh, A., Lee, D., Sopko, N., Matsui, H., Sabnekar, P., Liu, X., Elisseeff, J., Schoenberg, M. P., Pienta, K. & Bivalacqua, T. J. 2017 (Accepted/In press) In : Advanced Healthcare Materials.

Research output: Contribution to journalArticle

Patient Readmission
Hospital Costs
Cystectomy
Logistic Models
High-Volume Hospitals

Cavernous Nerve Injury by Radiation Therapy May Potentiate Erectile Dysfunction in Rats

Mahmood, J., Connors, C. Q., Alexander, A. A., Pavlovic, R., Samanta, S., Soman, S., Matsui, H., Sopko, N. A., Bivalacqua, T. J., Weinreich, D., Ho, C. Y., Eley, J., Sawant, A., Jackson, I. L. & Vujaskovic, Z. Nov 1 2017 In : International Journal of Radiation Oncology Biology Physics. 99, 3, p. 680-688 9 p.

Research output: Contribution to journalArticle

nerves
Erectile Dysfunction
rats
radiation therapy
Radiotherapy
Nerve Growth Factors
Ganglia
Type 2 Diabetes Mellitus
Down-Regulation
Gene Expression
Hematuria
Insurance
Databases
Carcinoma
Confidence Intervals
Organoids
Methylnitrosourea
Urinary Bladder Neoplasms
Cell Culture Techniques
Cell Line

Hospital Charges and Length of Stay Following Radical Cystectomy in the Enhanced Recovery After Surgery Era

Semerjian, A., Milbar, N., Kates, M., Gorin, M. A., Patel, H. D., Chalfin, H. J., Frank, S. M., Wu, C. L., Yang, W. W., Hobson, D., Robertson, L., Wick, E., Schoenberg, M. P., Pierorazio, P. M., Johnson, M. H., Stimson, C. J. & Bivalacqua, T. J. Jan 1 2017 (Accepted/In press) In : Urology.

Research output: Contribution to journalArticle

Hospital Charges
Cystectomy
Length of Stay
Renal Veins
Ileus

Immune-checkpoint status in penile squamous cell carcinoma: a North American cohort

Cocks, M., Taheri, D., Ball, M. W., Bezerra, S. M., Del Carmen Rodriguez, M., Ricardo, B. F. P., Bivalacqua, T. J., Sharma, R. B., Meeker, A., Chaux, A., Burnett, A. L. & Netto, G. J. Jan 1 2017 In : Human Pathology. 59, p. 55-61 7 p.

Research output: Contribution to journalArticle

Squamous Cell Carcinoma
Neoplasms
Stromal Cells
Penile Neoplasms
Surgical Pathology

Innumerable Condyloma Acuminatum Tumors of the Bladder

Murray, A. J., Bivalacqua, T. J. & Sopko, N. A. May 1 2017 In : Urology Case Reports. 12, p. 76-77 2 p.

Research output: Contribution to journalArticle

Condylomata Acuminata
Urinary Bladder Neoplasms
Genitalia
Urinary Bladder
Viruses

Intravesical BCG Induces CD4+ T-cell expansion in an immune competent model of bladder cancer

Kates, M., Nirschl, T., Sopko, N. A., Matsui, H., Kochel, C. M., Reis, L. O., Netto, G. J., Hoque, M., Hahn, N. M., McConkey, D. J., Baras, A. S., Drake, C. G. & Bivalacqua, T. J. Jul 1 2017 In : Cancer Immunology Research. 5, 7, p. 594-603 10 p.

Research output: Contribution to journalArticle

Mycobacterium bovis
Urinary Bladder Neoplasms
T-Lymphocytes
Adaptive Immunity
Urinary Bladder

Intravesical rAd–IFNa/Syn3 for patients with high-grade, bacillus calmette-guerin–refractory or relapsed non–muscle-invasive bladder cancer: A phase II randomized study

Shore, N. D. , Boorjian, S. A. , Canter, D. J. , Ogan, K. , Karsh, L. I. , Downs, T. M. , Gomella, L. G. , Kamat, A. M. , Lotan, Y. , Svatek, R. S. , Bivalacqua, T. J. , Grubb, R. L. , Krupski, T. L. , Lerner, S. P. , Woods, M. E. , Inman, B. A. , Milowsky, M. I. , Boyd, A. , Treasure, F. P. , Gregory, G. & 4 others Sawutz, D. G., Yla-Herttuala, S., Parker, N. R. & Dinney, C. P. N. Oct 20 2017 In : Journal of Clinical Oncology. 35, 30, p. 3410-3416 7 p.

Research output: Contribution to journalArticle

Mycobacterium bovis
Urinary Bladder Neoplasms
Interferon-alpha
Adenoviridae
Muscles

Longer average blood storage duration is associated with increased risk of infection and overall morbidity following radical cystectomy

Chappidi, M. R., Chalfin, H. J., Johnson, D. J., Kates, M., Sopko, N. A., Johnson, M. H., Liu, J. J., Frank, S. M. & Bivalacqua, T. J. Feb 1 2017 In : Urologic Oncology: Seminars and Original Investigations. 35, 2, p. 38.e17-38.e24

Research output: Contribution to journalArticle

Cystectomy
Morbidity
Infection
Odds Ratio
Blood Transfusion
Carcinoma
RNA Sequence Analysis
Prostatic Neoplasms
Renal Cell Carcinoma
Urinary Bladder Neoplasms

Lymph node density predicts recurrence and death after inguinal lymph node dissection for penile cancer

Ball, M. W., Schwen, Z. R., Ko, J. S., Meyer, A., Netto, G. J., Burnett, A. L. & Bivalacqua, T. J. Jan 1 2017 In : Investigative and Clinical Urology. 58, 1, p. 20-25 6 p.

Research output: Contribution to journalArticle

Penile Neoplasms
Groin
Lymph Node Excision
Lymph Nodes
Recurrence

M1 Macrophages Are Predominantly Recruited to the Major Pelvic Ganglion of the Rat Following Cavernous Nerve Injury

Matsui, H., Sopko, N. A., Hannan, J. L., Reinhardt, A. A., Kates, M., Yoshida, T., Liu, X., Castiglione, F., Hedlund, P., Weyne, E., Albersen, M. & Bivalacqua, T. J. Feb 1 2017 In : Journal of Sexual Medicine. 14, 2, p. 187-195 9 p.

Research output: Contribution to journalArticle

Ganglia
Macrophages
Wounds and Injuries
Erectile Dysfunction
Electric Stimulation

Penile Allotransplantation for Complex Genitourinary Reconstruction

Sopko, N. A., Tuffaha, S. H., Lough, D., Brandacher, G., Lee, W. P. A., Bivalacqua, T. J., Redett, R. J. & Burnett, A. L. 2017 (Accepted/In press) In : Journal of Urology.

Research output: Contribution to journalArticle

Vascularized Composite Allotransplantation
Transplantation
Transplants
Penis
Immunosuppression

Penile transplantation: An emerging option for genitourinary reconstruction

Tuffaha, S. H., Cooney, D. S., Sopko, N. A., Bivalacqua, T. J., Lough, D. M., Cooney, C. M., Brandacher, G., Lee, W. P. A., Burnett, A. L. & Redett, R. J. 2017 (Accepted/In press) In : Transplant International.

Research output: Contribution to journalArticle

Transplantation
Wounds and Injuries
Research

Pharmacodynamic and pharmacokinetic neoadjuvant study of hedgehog pathway inhibitor Sonidegib (LDE-225) in men with high-risk localized prostate cancer undergoing prostatectomy

Ross, A. E., Hughes, R. M., Glavaris, S., Ghabili, K., He, P., Anders, N. M., Harb, R., Tosoian, J. J., Marchionni, L., Schaeffer, E. M., Partin, A. W., Allaf, M. E., Bivalacqua, T. J., Chapman, C., O'Neal, T., DeMarzo, A. M., Hurley, P. J., Rudek, M. A. & Antonarakis, E. S. Jan 1 2017 In : Oncotarget. 8, 61, p. 104182-104192 11 p.

Research output: Contribution to journalArticle

Prostatectomy
Prostatic Neoplasms
Pharmacokinetics
Observation
Neoplasms
Robotics
Carcinoma
Recurrence
Urinary Tract
Neoplasms

Postoperative complications following intraoperative radiotherapy in abdominopelvic malignancy: A single institution analysis of 113 consecutive patients

Abdelfatah, E., Page, A., Sacks, J., Pierorazio, P., Bivalacqua, T., Efron, J., Terezakis, S., Gearhart, S., Fang, S., Safar, B., Pawlik, T. M., Armour, E., Hacker-Prietz, A., Herman, J. & Ahuja, N. Jun 1 2017 In : Journal of Surgical Oncology. 115, 7, p. 883-890 8 p.

Research output: Contribution to journalArticle

Radiotherapy
Neoplasms
Research Ethics Committees
Brachytherapy
Sarcoma

Preclinical evaluation of intravesical cisplatin nanoparticles for non–muscle-invasive bladder cancer

Kates, M., Date, A., Yoshida, T., Afzal, U., Kanvinde, P., Babu, T., Sopko, N. A., Matsui, H., Hahn, N. M., McConkey, D. J., Baras, A., Hanes, J., Ensign, L. & Bivalacqua, T. J. Nov 1 2017 In : Clinical Cancer Research. 23, 21, p. 6592-6601 10 p.

Research output: Contribution to journalArticle

Intravesical Administration
Urinary Bladder Neoplasms
Nanoparticles
Cisplatin
Muscles
Patient Readmission
Databases
Nephrectomy
Logistic Models
Patient Acceptance of Health Care

Reply

Chappidi, M. R., Kates, M. & Bivalacqua, T. J. 2017 (Accepted/In press) In : Urology.

Research output: Contribution to journalArticle

Rhoa/rock activation in major pelvic ganglion mediates caspase-3 dependent nitrergic neuronal apoptosis following cavernous nerve injury

Bell, M., Sopko, N. A., Matsui, H., Hannan, J. L. & Bivalacqua, T. J. Apr 1 2017 In : Neural Regeneration Research. 12, 4, p. 572-573 2 p.

Research output: Contribution to journalComment/debate

Ganglia
Caspase 3
Apoptosis
Wounds and Injuries

Spectrum of genetic mutations in de novo PUNLMP of the urinary bladder

Rodriguez Pena, M. D. C., Tregnago, A. C., Eich, M. L., Springer, S., Wang, Y., Taheri, D., Ertoy, D., Fujita, K., Bezerra, S. M., Cunha, I. W., Raspollini, M. R., Yu, L., Bivalacqua, T. J., Papadopoulos, N., Kinzler, K. W., Vogelstein, B. & Netto, G. J. Jun 8 2017 (Accepted/In press) In : Virchows Archiv. p. 1-7 7 p.

Research output: Contribution to journalArticle

Urinary Bladder
Mutation
Neoplasms
Urinary Bladder Neoplasms
Genes

The Epidemiology and Pathophysiology of Erectile Dysfunction and the Role of Environment-Current Updates

Collica, S., Pederzoli, F. & Bivalacqua, T. Nov 14 2017 Bioenvironmental Issues Affecting Men's Reproductive and Sexual Health. Elsevier Inc., p. 439-455 17 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Erectile Dysfunction
Epidemiology
amsonic acid
Aphrodisiacs
Penile Erection

Urinary Tissue Engineering: Challenges and Opportunities

Singh, A., Bivalacqua, T. J. & Sopko, N. 2017 (Accepted/In press) In : Sexual Medicine Reviews.

Research output: Contribution to journalArticle

Tissue Engineering
Urothelium
Urine
Regeneration
Collagen

Use of regenerative tissue for urinary diversion

Sopko, N. A., Kates, M., Singh, A., Steinberg, G. D., Smith, N. D., Schoenberg, M. P. & Bivalacqua, T. J. Apr 20 2017 Urinary Diversion. Springer International Publishing, p. 81-99 19 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Urinary Diversion