Find Research Outputs

Search concepts
Selected Filters
2017

B-cell depletion - A frontier in monoclonal antibodies for multiple sclerosis

Calabresi, P. A. Jan 19 2017 In : New England Journal of Medicine. 376, 3, p. 280-282 3 p.

Research output: Research - peer-reviewEditorial

CNS-targeted autoimmunity leads to increased influenza mortality in mice

Glenn, J. D., Smith, M. D., Xue, P., Chan-Li, Y., Collins, S., Calabresi, P. A., Horton, M. R. & Whartenby, K. A. 2017 In : Journal of Experimental Medicine. 214, 2, p. 297-307 11 p.

Research output: Research - peer-reviewArticle

Autoimmune Experimental Encephalomyelitis
Autoimmunity
Human Influenza
Central Nervous System
Lung

Disease-modifying therapies modulate retinal atrophy in multiple sclerosis: A retrospective study

Button, J., Al-Louzi, O., Lang, A., Bhargava, P., Newsome, S. D., Frohman, T., Balcer, L. J., Frohman, E. M., Prince, J., Calabresi, P. A. & Saidha, S. Feb 7 2017 In : Neurology. 88, 6, p. 525-532 8 p.

Research output: Research - peer-reviewArticle

Multiple Sclerosis
Atrophy
Retrospective Studies
Therapeutics
Optical Coherence Tomography

From neurofilament research to multiple sclerosis clinical practice: Where do we stand?

Bodini, B. & Calabresi, P. A. Feb 28 2017 In : Neurology. 88, 9, p. 816-817 2 p.

Research output: Research - peer-reviewEditorial

Gradient nonlinearity effects on upper cervical spinal cord area measurement from 3D T1-weighted brain MRI acquisitions

Papinutto, N. , Bakshi, R. , Bischof, A. , Calabresi, P. A. , Caverzasi, E. , Constable, R. T. , Datta, E. , Kirkish, G. , Nair, G. , Oh, J. , Pelletier, D. , Pham, D. L. , Reich, D. S. , Rooney, W. , Roy, S. , Schwartz, D. , Shinohara, R. T. , Sicotte, N. L. , Stern, W. A. , Tagge, I. & 3 others Tauhid, S., Tummala, S. & Henry, R. G. 2017 (Accepted/In press) In : Magnetic Resonance in Medicine.

Research output: Research - peer-reviewArticle

Brain
Cervical Cord
Multiple Sclerosis
Healthy Volunteers

Lineage tracing reveals dynamic changes in oligodendrocyte precursor cells following cuprizone-induced demyelination

Baxi, E. G., Debruin, J., Jin, J., Strasburger, H. J., Smith, M. D., Orthmann-Murphy, J. L., Schott, J. T., Fairchild, A. N., Bergles, D. E. & Calabresi, P. A. 2017 (Accepted/In press) In : GLIA.

Research output: Research - peer-reviewArticle

Cuprizone
Oligodendroglia
Demyelinating Diseases
Stem Cells
Gray Matter

Longitudinal multiple sclerosis lesion segmentation: Resource and challenge

Carass, A. , Roy, S. , Jog, A. , Cuzzocreo, J. L. , Magrath, E. , Gherman, A. , Button, J. , Nguyen, J. , Prados, F. , Sudre, C. H. , Jorge Cardoso, M. , Cawley, N. , Ciccarelli, O. , Wheeler-Kingshott, C. A. M. , Ourselin, S. , Catanese, L. , Deshpande, H. , Maurel, P. , Commowick, O. , Barillot, C. & 26 others Tomas-Fernandez, X., Warfield, S. K., Vaidya, S., Chunduru, A., Muthuganapathy, R., Krishnamurthi, G., Jesson, A., Arbel, T., Maier, O., Handels, H., Iheme, L. O., Unay, D., Jain, S., Sima, D. M., Smeets, D., Ghafoorian, M., Platel, B., Birenbaum, A., Greenspan, H., Bazin, P. L., Calabresi, P. A., Crainiceanu, C. M., Ellingsen, L. M., Reich, D. S., Prince, J. L. & Pham, D. L. Mar 1 2017 In : NeuroImage. 148, p. 77-102 26 p.

Research output: Research - peer-reviewArticle

Multiple Sclerosis
Datasets
Research Personnel
Research
White Matter

Longitudinal multiple sclerosis lesion segmentation data resource

Carass, A., Roy, S., Jog, A., Cuzzocreo, J. L., Magrath, E., Gherman, A., Button, J., Nguyen, J., Bazin, P. L., Calabresi, P. A., Crainiceanu, C. M., Ellingsen, L. M., Reich, D. S., Prince, J. L. & Pham, D. L. Jun 1 2017 In : Data in Brief. 12, p. 346-350 5 p.

Research output: Research - peer-reviewArticle

multiple sclerosis
resources
segmentation
time
website

Multiple Sclerosis Lesion Segmentation Using Joint Label Fusion

Dong, M., Oguz, I., Subbana, N., Calabresi, P., Shinohara, R. T. & Yushkevich, P. 2017 Patch-Based Techniques in Medical Imaging - 3rd International Workshop, Patch-MI 2017 Held in Conjunction with MICCAI 2017, Proceedings. Springer Verlag, Vol. 10530 LNCS, p. 138-145 8 p. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); vol. 10530 LNCS)

Research output: ResearchConference contribution

Multiple Sclerosis
Atlas
Fusion
Segmentation
Labels

Neuropsychiatric syndromes of multiple sclerosis

Murphy, R., O'Donoghue, S., Counihan, T., McDonald, C., Calabresi, P. A., Ahmed, M. A. S., Kaplin, A. & Hallahan, B. Aug 1 2017 In : Journal of Neurology, Neurosurgery and Psychiatry. 88, 8, p. 697-708 12 p.

Research output: Research - peer-reviewReview article

Multiple Sclerosis
Syndrome
Illness
Etiology
Progression
Optical Coherence Tomography
Multiple Sclerosis
Neurodegenerative Diseases
Biomarkers
Technology
Relapsing-Remitting Multiple Sclerosis
Randomized Controlled Trials
Magnetic Resonance Imaging
peginterferon beta-1a
Therapeutics

Quantitative measures of walking and strength provide insight into brain corticospinal tract pathology in multiple sclerosis

Fritz, N. E., Keller, J., Calabresi, P. A. & Zackowski, K. M. 2017 In : NeuroImage: Clinical. 14, p. 490-498 9 p.

Research output: Research - peer-reviewArticle

Pyramidal Tracts
Multiple Sclerosis
Walking
Pathology
Brain

Retinal architecture and melanopsin-mediated pupillary response characteristics: A putative pathophysiologic signature for the retino-hypothalamic tract in multiple sclerosis

Meltzer, E., Sguigna, P. V., Subei, A., Beh, S., Kildebeck, E., Conger, D., Conger, A., Lucero, M., Frohman, B. S., Frohman, A. N., Saidha, S., Galetta, S., Calabresi, P. A., Rennaker, R., Frohman, T. C., Kardon, R. H., Balcer, L. J. & Frohman, E. M. May 1 2017 In : JAMA Neurology. 74, 5, p. 574-582 9 p.

Research output: Research - peer-reviewArticle

Multiple Sclerosis
melanopsin
Constriction
Light
Optical Coherence Tomography

Retinal degeneration in primary-progressive multiple sclerosis: A role for cortical lesions?

Petracca, M., Cordano, C., Cellerino, M., Button, J., Krieger, S., Vancea, R., Ghassemi, R., Farrell, C., Miller, A., Calabresi, P. A., Lublin, F. & Inglese, M. 2017 In : Multiple Sclerosis. 23, 1, p. 43-50 8 p.

Research output: Research - peer-reviewArticle

Chronic Progressive Multiple Sclerosis
Retinal Degeneration
Ganglia
Nerve Fibers
Visual Pathways

Retrograde trans-synaptic visual pathway degeneration in multiple sclerosis: A case series

Al-Louzi, O., Button, J., Newsome, S. D., Calabresi, P. A. & Saidha, S. Jun 1 2017 In : Multiple Sclerosis. 23, 7, p. 1035-1039 5 p.

Research output: Research - peer-reviewArticle

Retrograde Degeneration
Visual Pathways
Ganglia
Multiple Sclerosis
Nervous System

Thalamus segmentation using multi-modal feature classification: Validation and pilot study of an age-matched cohort

Glaister, J., Carass, A., NessAiver, T., Stough, J. V., Saidha, S., Calabresi, P. A. & Prince, J. L. Sep 1 2017 In : NeuroImage. 158, p. 430-440 11 p.

Research output: Research - peer-reviewArticle

Validation Studies
Thalamus
Diffusion Tensor Imaging
Atlases
Multiple Sclerosis

Therapeutic Application of Monoclonal Antibodies in Multiple Sclerosis

Orthmann-Murphy, J. L. & Calabresi, P. A. Jan 1 2017 In : Clinical Pharmacology and Therapeutics. 101, 1, p. 52-64 13 p.

Research output: Research - peer-reviewArticle

Multiple Sclerosis
Monoclonal Antibodies
Therapeutics
Central Nervous System
Immunomodulation

Towards topological correct segmentation of macular OCT from cascaded FCNs

He, Y., Carass, A., Yun, Y., Zhao, C., Jedynak, B. M., Solomon, S. D., Saidha, S., Calabresi, P. A. & Prince, J. L. 2017 Fetal, Infant and Ophthalmic Medical Image Analysis - International Workshop, FIFI 2017 and 4th International Workshop, OMIA 2017 Held in Conjunction with MICCAI 2017, Proceedings. Springer Verlag, Vol. 10554 LNCS, p. 202-209 8 p. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); vol. 10554 LNCS)

Research output: ResearchConference contribution

Optical Coherence Tomography
Segmentation
Optical tomography
Topology
Retina
2016

20/40 or better visual acuity after optic neuritis: Not as good as we once thought?

Sabadia, S. B., Nolan, R. C., Galetta, K. M., Narayana, K. M., Wilson, J. A., Calabresi, P. A., Frohman, E. M., Galetta, S. L. & Balcer, L. J. 2016 In : Journal of Neuro-Ophthalmology. 36, 4, p. 369-376 8 p.

Research output: Research - peer-reviewArticle

Optic Neuritis
Visual Acuity
Nerve Fibers
Ganglia
Quality of Life

Adapted resistance training improves strength in eight weeks in individuals with multiple sclerosis

Keller, J. L., Fritz, N., Chiang, C. C., Jiang, A., Thompson, T., Cornet, N., Newsome, S. D., Calabresi, P. A. & Zackowski, K. Jan 29 2016 In : Journal of Visualized Experiments. 2016, 107, e53449

Research output: Research - peer-reviewArticle

Resistance Training
Multiple Sclerosis
Direction compound
Education
Hip

Author Response

Sotirchos, E. S. & Calabresi, P. A. Sep 27 2016 In : Neurology. 87, 13, p. 1424 1 p.

Research output: Research - peer-reviewLetter

Combined registration and motion correction of longitudinal retinal OCT data

Lang, A., Carass, A., Al-Louzi, O., Bhargava, P., Solomon, S. D., Calabresi, P. A. & Prince, J. L. 2016 Medical Imaging 2016: Image Processing. SPIE, Vol. 9784, 97840X

Research output: ResearchConference contribution

tomography
Optical tomography
Optical Coherence Tomography
Thickness measurement
Eye movements

Differentiating neuromyelitis optica from other causes of longitudinally extensive transverse myelitis on spinal magnetic resonance imaging

Pekcevik, Y., Mitchell, C. H., Mealy, M. A., Orman, G., Lee, I. H., Newsome, S. D., Thompson, C. B., Pardo, C. A., Calabresi, P. A., Levy, M. & Izbudak, I. 2016 In : Multiple Sclerosis. 22, 3, p. 302-311 10 p.

Research output: Research - peer-reviewArticle

Transverse Myelitis
Neuromyelitis Optica
Magnetic Resonance Imaging
Brain
Spinal Cord

How global MS prevalence is changing: A retrospective chart review in the United Arab Emirates

Schiess, N., Huether, K., Fatafta, T., Fitzgerald, K. C., Calabresi, P. A., Blair, I., Alsaadi, T. & Szolics, M. Sep 1 2016 In : Multiple Sclerosis and Related Disorders. 9, p. 73-79 7 p.

Research output: Research - peer-reviewArticle

United Arab Emirates
Multiple Sclerosis
Middle East
Incidence
Age of Onset

Increased TNFR1 expression and signaling in injured peripheral nerves of mice with reduced BACE1 activity

Liu, L., Fissel, J. A., Tasnim, A., Borzan, J., Gocke, A., Calabresi, P. A. & Farah, M. H. Sep 1 2016 In : Neurobiology of Disease. 93, p. 21-27 7 p.

Research output: Research - peer-reviewArticle

Tumor Necrosis Factor Receptors
Peripheral Nerves
Enzymes
Macrophages
Knockout Mice

Intensity inhomogeneity correction of macular OCT using N3 and retinal flatspace

Lang, A., Carass, A., Jedynak, B. M., Solomon, S. D., Calabresi, P. A. & Prince, J. L. Jun 15 2016 2016 IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI 2016 - Proceedings. IEEE Computer Society, Vol. 2016-June, p. 197-200 4 p. 7493243

Research output: ResearchConference contribution

Optical tomography
Optical Coherence Tomography
Magnetic resonance imaging
Imaging techniques
Processing

Is my MS patient failing treatment?

Butzkueven, H. & Calabresi, P. A. Jul 12 2016 In : Neurology. 87, 2, p. 124-125 2 p.

Research output: Research - peer-reviewEditorial

Lesion heterogeneity on high-field susceptibility MRI Is associated with multiple sclerosis severity

Harrison, D. M., Li, X., Liu, H., Jones, C. K., Caffo, B., Calabresi, P. A. & Van Zijl, P. Aug 1 2016 In : American Journal of Neuroradiology. 37, 8, p. 1447-1453 7 p.

Research output: Research - peer-reviewArticle

Multiple Sclerosis
Fatigue
Oligodendroglia
Iron
Inflammation

Magnetic susceptibility contrast variations in multiple sclerosis lesions

Li, X., Harrison, D. M., Liu, H., Jones, C. K., Oh, J., Calabresi, P. A. & Van Zijl, P. C. M. Feb 1 2016 In : Journal of Magnetic Resonance Imaging. 43, 2, p. 463-473 11 p.

Research output: Research - peer-reviewArticle

Multiple Sclerosis
Magnetic Resonance Imaging
Masks
Myelin Sheath
Iron

Metabolomics in multiple sclerosis

Bhargava, P. & Calabresi, P. A. Apr 1 2016 In : Multiple Sclerosis. 22, 4, p. 451-460 10 p.

Research output: Research - peer-reviewArticle

Metabolomics
Multiple Sclerosis
Precision Medicine
Demyelinating Diseases
Genomics

Multiple Sclerosis

Schiess, N. & Calabresi, P. A. Aug 1 2016 In : Seminars in Neurology. 36, 4, p. 350-356 7 p.

Research output: Research - peer-reviewArticle

Multiple Sclerosis
Immunomodulation
Neurology
Cognition
Differential Diagnosis

Outer retinal changes following acute optic neuritis

Al-Louzi, O. A., Bhargava, P., Newsome, S. D., Balcer, L. J., Frohman, E. M., Crainiceanu, C., Calabresi, P. A. & Saidha, S. 2016 In : Multiple Sclerosis. 22, 3, p. 362-372 11 p.

Research output: Research - peer-reviewArticle

Optic Neuritis
Ganglia
Optical Coherence Tomography
Nerve Fibers
Multiple Sclerosis

Pain, cognition and quality of life associate with structural measures of brain volume loss in multiple sclerosis

Fritz, N. E., Roy, S., Keller, J., Prince, J., Calabresi, P. A. & Zackowski, K. M. Oct 14 2016 In : NeuroRehabilitation. 39, 4, p. 535-544 10 p.

Research output: Research - peer-reviewArticle

Cognition
Multiple Sclerosis
Quality of Life
Pain
Brain

Phenytoin in acute optic neuritis: neuroprotective or not?

Saidha, S. & Calabresi, P. A. Mar 1 2016 In : The Lancet Neurology. 15, 3, p. 233-235 3 p.

Research output: Research - peer-reviewComment/debate

Myelin Proteins
Neurology
Rats
Assays
Fluorescence

Retinal thickness measured with optical coherence tomography and risk of disability worsening in multiple sclerosis: A cohort study

Martinez-Lapiscina, E. H. , Arnow, S. , Wilson, J. A. , Saidha, S. , Preiningerova, J. L. , Oberwahrenbrock, T. , Brandt, A. U. , Pablo, L. E. , Guerrieri, S. , Gonzalez, I. , Outteryck, O. , Mueller, A. K. , Albrecht, P. , Chan, W. , Lukas, S. , Balk, L. J. , Fraser, C. , Frederiksen, J. L. , Resto, J. , Frohman, T. & 23 others Cordano, C., Zubizarreta, I., Andorra, M., Sanchez-Dalmau, B., Saiz, A., Bermel, R., Klistorner, A., Petzold, A., Schippling, S., Costello, F., Aktas, O., Vermersch, P., Oreja-Guevara, C., Comi, G., Leocani, L., Garcia-Martin, E., Paul, F., Havrdova, E., Frohman, E., Balcer, L. J., Green, A. J., Calabresi, P. A. & Villoslada, P. May 1 2016 In : The Lancet Neurology. 15, 6, p. 574-584 11 p.

Research output: Research - peer-reviewArticle

Optical Coherence Tomography
Multiple Sclerosis
Cohort Studies
Optic Neuritis
Nerve Fibers

Safety and immunologic effects of high-vs low-dose cholecalciferol in multiple sclerosis

Sotirchos, E. S., Bhargava, P., Eckstein, C., Van Haren, K., Baynes, M., Ntranos, A., Gocke, A., Steinman, L., Mowry, E. M. & Calabresi, P. A. Jan 26 2016 In : Neurology. 86, 4, p. 382-390 9 p.

Research output: Research - peer-reviewArticle

Cholecalciferol
Multiple Sclerosis
T-Lymphocytes
Safety
Interleukin-17

Simultaneous segmentation of retinal surfaces and microcystic macular edema in SDOCT volumes

Antony, B. J., Lang, A., Swingle, E. K., Al-Louzi, O., Carass, A., Solomon, S., Calabresi, P. A., Saidha, S. & Prince, J. L. 2016 Medical Imaging 2016: Image Processing. SPIE, Vol. 9784, 97841C

Research output: ResearchConference contribution

Macular Edema
Optical tomography
edema
Imaging techniques
Optical Coherence Tomography

Systemic tolerance mediated by melanoma brain tumors is reversible by radiotherapy and vaccination

Jackson, C. M., Kochel, C. M., Nirschl, C. J., Durham, N. M., Ruzevick, J., Alme, A., Francica, B. J., Elias, J., Daniels, A., Dubensky, T. W., Lauer, P., Brockstedt, D. G., Baxi, E. G., Calabresi, P. A., Taube, J. M., Pardo, C. A., Brem, H., Pardoll, D. M., Lim, M. & Drake, C. G. Mar 1 2016 In : Clinical Cancer Research. 22, 5, p. 1161-1172 12 p.

Research output: Research - peer-reviewArticle

Central Nervous System Neoplasms
Brain Neoplasms
Melanoma
Vaccination
Radiotherapy

Thalamus parcellation using multi-modal feature classification and thalamic nuclei priors

Glaister, J., Carass, A., Stough, J. V., Calabresi, P. A. & Prince, J. L. 2016 Medical Imaging 2016: Image Processing. SPIE, Vol. 9784, 97843J

Research output: ResearchConference contribution

thalamus
nuclei
Thalamic Nuclei
Thalamus
classifiers

The APOSTEL recommendations for reporting quantitative optical coherence tomography studies

Cruz-Herranz, A., Balk, L. J., Oberwahrenbrock, T., Saidha, S., Martinez-Lapiscina, E. H., Lagreze, W. A., Schuman, J. S., Villoslada, P., Calabresi, P., Balcer, L., Petzold, A., Green, A. J., Paul, F., Brandt, A. U. & Albrecht, P. Jun 14 2016 In : Neurology. 86, 24, p. 2303-2309 7 p.

Research output: Research - peer-reviewReview article

Optical Coherence Tomography
Terminology
Consensus
Group Processes
Checklist

The emergence of neuroepidemiology, neurovirology and neuroimmunology: the legacies of John F. Kurtzke and Richard ‘Dick’ T. Johnson

Kildebeck, E. J., Narayan, R., Nath, A., Weiner, H., Beh, S., Calabresi, P. A., Steinman, L., Major, E. O., Frohman, T. C. & Frohman, E. M. Oct 12 2016 (Accepted/In press) In : Journal of Neurology. p. 1-12 12 p.

Research output: Research - peer-reviewArticle

Voxel based morphometry in optical coherence tomography: Validation & core findings

Antony, B. J., Chen, M., Carass, A., Jedynak, B. M., Al-Louzi, O., Solomon, S. D., Saidha, S., Calabresi, P. A. & Prince, J. L. 2016 Medical Imaging 2016: Biomedical Applications in Molecular, Structural, and Functional Imaging. SPIE, Vol. 9788, 97880P

Research output: ResearchConference contribution

Optical Coherence Tomography
Optical tomography
tomography
Multiple Sclerosis
Population
2015
Multiple Sclerosis
T-Lymphocytes
1,25-dihydroxyvitamin D
In Vitro Techniques
Vitamin D

Antigenic stimulation of Kv1.3-deficient Th cells gives rise to a population of Foxp3-independent T cells with suppressive properties

Grishkan, I. V., Tosi, D. M., Bowman, M. D., Harary, M., Calabresi, P. A. & Gocke, A. R. Aug 15 2015 In : Journal of Immunology. 195, 4, p. 1399-1407 9 p.

Research output: Research - peer-reviewArticle

T-Lymphocytes
Population
Multiple Sclerosis
Myelin-Oligodendrocyte Glycoprotein
Autoimmune Experimental Encephalomyelitis
Cognition
Multiple Sclerosis
Magnetic Resonance Imaging
White Matter
Odds Ratio

Automatic segmentation of microcystic macular edema in OCT

Lang, A., Carass, A., Swingle, E. K., Al-Louzi, O., Bhargava, P., Saidha, S., Ying, H. S., Calabresi, P. A. & Prince, J. L. Jan 1 2015 In : Biomedical Optics Express. 6, 1, p. 155-169 15 p.

Research output: Research - peer-reviewArticle

edema
tomography
Macular Edema
Optical Coherence Tomography
classifiers

Erratum: Corrigendum to “Statistical normalization techniques for magnetic resonance imaging” (NeuroImage: Clinical (2014) 6 (9-19))

Shinohara, R. T., Sweeney, E. M., Goldsmith, J., Shiee, N., Mateen, F. J., Calabresi, P. A., Jarso, S., Pham, D. L., Reich, D. S. & Crainiceanu, C. M. Dec 1 2015 In : NeuroImage: Clinical. 7, p. 848 1 p.

Research output: Research - peer-reviewComment/debate

Biostatistics
Baltimore
Magnetic Resonance Imaging
corrigendum