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2020
Desperate Times: Protecting the Public From Research Without Consent or Oversight During Public Health Emergencies
Beach, M. C., Lederman, H. M., Singleton, M., Brower, R. G., Carrese, J., Ford, D. E., Hansoti, B., Hendrix, C. W., Jorgensen, E. V., Moore, R. D., Rocca, P. & Zenilman, J. M., Dec 1 2020, In: Annals of internal medicine. 173, 11, p. 926-928 3 p.Research output: Contribution to journal › Editorial › peer-review
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Effect of Hydroxychloroquine on Clinical Status at 14 Days in Hospitalized Patients with COVID-19: A Randomized Clinical Trial
Self, W. H., Semler, M. W., Leither, L. M., Casey, J. D., Angus, D. C., Brower, R. G., Chang, S. Y., Collins, S. P., Eppensteiner, J. C., Filbin, M. R., Files, D. C., Gibbs, K. W., Ginde, A. A., Gong, M. N., Harrell, F. E., Hayden, D. L., Hough, C. L., Johnson, N. J., Khan, A., Lindsell, C. J. & 13 others, , Dec 1 2020, In: JAMA - Journal of the American Medical Association. 324, 21, p. 2165-2176 12 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Mean Airway Pressure As a Predictor of 90-Day Mortality in Mechanically Ventilated Patients∗
INTENSIVOS Cohort Study, 2020, (Accepted/In press) In: Critical care medicine. p. 688-695 8 p.Research output: Contribution to journal › Article › peer-review
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Peep titration to minimize driving pressure in subjects with ards: A prospective physiological study
Sahetya, S. K., Hager, D. N., Stephens, R. S., Needham, D. M. & Brower, R. G., May 1 2020, In: Respiratory care. 65, 5, p. 583-589 7 p.Research output: Contribution to journal › Article › peer-review
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Premature, Opportune, and Delayed Weaning in Mechanically Ventilated Patients: A Call for Implementation of Weaning Protocols in Low-and Middle-Income Countries
INTENSIVOS Cohort Study, 2020, (Accepted/In press) In: Critical care medicine. p. 673-679 7 p.Research output: Contribution to journal › Article › peer-review
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Rationale and design of ORCHID: A randomized placebo-controlled clinical trial of hydroxychloroquine for adults hospitalized with COVID-19
ORCHID Protocol Committee and the National Heart, Lung, and Blood Institute Prevention and Early Treatment of Acute Lung Injury (PETAL) Network Investigators, Sep 2020, In: Annals of the American Thoracic Society. 17, 9, p. 1144-1153 10 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Voice-Related Quality of Life Increases With a Talking Tracheostomy Tube: A Randomized Controlled Trial
Pandian, V., Cole, T., Kilonsky, D., Holden, K., Feller-Kopman, D. J., Brower, R. & Mirski, M., May 1 2020, In: Laryngoscope. 130, 5, p. 1249-1255 7 p.Research output: Contribution to journal › Article › peer-review
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2018
Can the plateau be higher than the peak pressure?
Sajjad, H., Schmidt, G. A., Brower, R. G. & Eberlein, M., Jun 2018, In: Annals of the American Thoracic Society. 15, 6, p. 754-759 6 p.Research output: Contribution to journal › Review article › peer-review
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Catheter-directed thrombolysis for intermediate-risk pulmonary embolism
Furfaro, D., Stephens, R., Streiff, M. B. & Brower, R. G., Feb 1 2018, In: Annals of the American Thoracic Society. 15, 2, p. 134-144 11 p.Research output: Contribution to journal › Article › peer-review
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Chest wall strapping increases expiratory airflow and detectable airway segments in computer tomographic scans of normal and obstructed lungs
Taher, H., Bauer, C., Abston, E., Kaczka, D. W., Bhatt, S. P., Zabner, J., Brower, R. G., Beichel, R. R. & Eberlein, M., May 2018, In: Journal of applied physiology. 124, 5, p. 1186-1193 8 p.Research output: Contribution to journal › Article › peer-review
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ECMO for severe acute respiratory distress syndrome
Shanholtz, C., Reed, R. M. & Brower, R. G., Sep 13 2018, In: New England Journal of Medicine. 379, 11, p. 1090 1 p.Research output: Contribution to journal › Letter › peer-review
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Mechanical ventilation in adults with acute respiratory distress syndrome: An official clinical guideline of American Thoracic Society/European Society of Intensive Care medicine/Society of Critical care medicine
Fan, E., Del Sorbo, L., Goligher, E. C., Hodgson, C. L., Munshi, L., Walkey, A. J., Adhikari, N. K. J., Amato, M. B. P., Branson, R., Brower, R. G., Ferguson, N. D., Gajic, O., Gattinoni, L., Hess, D., Mancebo, J., Meade, M. O., McAuley, D. F., Pesenti, A., Ranieri, V. M., Rubenfeld, G. D. & 9 others, , 2018, In: Pulmonologiya. 28, 4, p. 399-410 12 p.Research output: Contribution to journal › Article › peer-review
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Minimally invasive palliative interventions in advanced lung cancer
Mallow, C., Hayes, M., Semaan, R., Smith, T., Hales, R., Brower, R. & Yarmus, L., Jul 3 2018, In: Expert review of respiratory medicine. 12, 7, p. 605-614 10 p.Research output: Contribution to journal › Review article › peer-review
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Oxygen Exposure Resulting in Arterial Oxygen Tensions Above the Protocol Goal Was Associated With Worse Clinical Outcomes in Acute Respiratory Distress Syndrome
National Institutes of Health Acute Respiratory Distress Syndrome Network Investigators, Apr 1 2018, In: Critical care medicine. 46, 4, p. 517-524 8 p.Research output: Contribution to journal › Article › peer-review
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Progressive myocardial injury is associated with mortality in the acute respiratory distress syndrome
Metkus, T. S., Guallar, E., Sokoll, L., Morrow, D. A., Tomaselli, G., Brower, R., Kim, B. S., Schulman, S. & Korley, F. K., Dec 2018, In: Journal of Critical Care. 48, p. 26-31 6 p.Research output: Contribution to journal › Article › peer-review
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Risk factors for mortality and mortality rates in interstitial lung disease patients in the intensive care unit
Huapaya, J. A., Wilfong, E. M., Harden, C. T., Brower, R. G. & Danoff, S., Dec 31 2018, In: European respiratory review : an official journal of the European Respiratory Society. 27, 150Research output: Contribution to journal › Review article › peer-review
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Survival of patients with severe acute respiratory distress syndrome treated without extracorporeal membrane oxygenation
Sahetya, S. K., Brower, R. G. & Stephens, R. S., May 1 2018, In: American Journal of Critical Care. 27, 3, p. 220-227 8 p.Research output: Contribution to journal › Article › peer-review
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2016
Mechanical ventilation in the acute respiratory distress syndrome
Brower, R. G. & Brochard, L., Apr 19 2016, Acute Respiratory Distress Syndrome, Second Edition. CRC Press, p. 335-358 24 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter
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Nonlinear Imputation of PaO2/FIO2 From SpO2/FIO2 Among Patients With Acute Respiratory Distress Syndrome
Brown, S. M., Grissom, C. K., Moss, M., Rice, T. W., Schoenfeld, D., Hou, P. C., Thompson, B. T. & Brower, R. G., Aug 1 2016, In: CHEST. 150, 2, p. 307-313 7 p.Research output: Contribution to journal › Article › peer-review
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The creation of a biocontainment unit at a Tertiary Care Hospital the Johns Hopkins Medicine Experience
Garibaldi, B. T., Kelen, G. D., Brower, R. G., Bova, G., Ernst, N., Reimers, M., Langlotz, R., Gimburg, A., Iati, M., Smith, C., MacConnell, S., James, H., Lewin, J. J., Trexler, P., Black, M. A., Lynch, C., Clarke, W., Marzinke, M. A., Sokoll, L. J., Carroll, K. C. & 11 others, , May 1 2016, In: Annals of the American Thoracic Society. 13, 5, p. 600-608 9 p.Research output: Contribution to journal › Review article › peer-review
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The promises and problems of transpulmonary pressure measurements in acute respiratory distress syndrome
Sahetya, S. K. & Brower, R. G., 2016, In: Current opinion in critical care. 22, 1, p. 7-13 7 p.Research output: Contribution to journal › Review article › peer-review
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What’s new in ARDS: can we prevent it?
Brower, R. G. & Antonelli, M., May 1 2016, In: Intensive Care Medicine. 42, 5, p. 772-774 3 p.Research output: Contribution to journal › Editorial › peer-review
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2015
Body temperature and mortality in patients with acute respiratory distress syndrome
The National heart, Lung, and Blood Institute Acute Respiratory distress syndrome Network, 2015, In: American Journal of Critical Care. 24, 1, p. 15-23 9 p.Research output: Contribution to journal › Article › peer-review
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Establishment of a prospective cohort of mechanically ventilated patients in five intensive care units in Lima, Peru: Protocol and organisational characteristics of participating centres
INTENSIVOS Cohort Study, 2015, In: BMJ open. 5, 1, e005803.Research output: Contribution to journal › Article › peer-review
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Fluid management with a simplified conservative protocol for the acute respiratory distress syndrome
Grissom, C. K., Hirshberg, E. L., Dickerson, J. B., Brown, S. M., Lanspa, M. J., Liu, K. D., Schoenfeld, D., Tidswell, M., Hite, R. D., Rock, P., Miller, R. R., Morris, A. H., Hudson, L., Gundel, S., Hough, C., Neff, M., Sims, K., Ungar, A., Watkins, T., Steingrub, J. & 190 others, , Feb 1 2015, In: Critical care medicine. 43, 2, p. 288-295 8 p.Research output: Contribution to journal › Article › peer-review
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Lung size mismatch and primary graft dysfunction after bilateral lung transplantation
Eberlein, M., Reed, R. M., Bolukbas, S., Diamond, J. M., Wille, K. M., Orens, J. B., Brower, R. G. & Christie, J. D., Feb 1 2015, In: Journal of Heart and Lung Transplantation. 34, 2, p. 233-240 8 p.Research output: Contribution to journal › Article › peer-review
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Neuromuscular electrical stimulation in mechanically ventilated patients: A randomized, sham-controlled pilot trial with blinded outcome assessment
Kho, M. E., Truong, A. D., Zanni, J. M., Ciesla, N. D., Brower, R. G., Palmer, J. B. & Needham, D. M., Feb 1 2015, In: Journal of Critical Care. 30, 1, p. 32-39 8 p.Research output: Contribution to journal › Article › peer-review
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Standardizing predicted body weight equations for mechanical ventilation tidal volume settings
Linares-Perdomo, O., East, T. D., Brower, R. & Morris, A. H., Jul 1 2015, In: CHEST. 148, 1, p. 73-78 6 p.Research output: Contribution to journal › Article › peer-review
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The ten diseases that look like ARDS
Guérin, C., Thompson, T. & Brower, R., Dec 20 2015, In: Intensive Care Medicine. 41, 6, p. 1099-1102 4 p.Research output: Contribution to journal › Article › peer-review
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Timing of low tidal volume ventilation and intensive care unit mortality in acute respiratory distress syndrome:A Prospective Cohort Study
Needham, D. M., Yang, T., Dinglas, V. D., Mendez-Tellez, P. A., Shanholtz, C., Sevransky, J. E., Brower, R. G., Pronovost, P. J. & Colantuoni, E., Jan 15 2015, In: American journal of respiratory and critical care medicine. 191, 2, p. 177-185 9 p.Research output: Contribution to journal › Article › peer-review
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2014
Chest wall strapping: An old physiology experiment with new relevance to small airways diseases
Eberlein, M., Schmidt, G. A. & Brower, R. G., Oct 1 2014, In: Annals of the American Thoracic Society. 11, 8, p. 1258-1266 9 p.Research output: Contribution to journal › Article › peer-review
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Developing, Implementing, and Evaluating a Multifaceted Quality Improvement Intervention to Promote Sleep in an ICU
Kamdar, B. B., Yang, J., King, L. M., Neufeld, K. J., Bienvenu, O. J., Rowden, A. M., Brower, R. G., Collop, N. A. & Needham, D. M., Nov 8 2014, In: American Journal of Medical Quality. 29, 6, p. 546-554 9 p.Research output: Contribution to journal › Article › peer-review
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Driving pressure and survival in the acute respiratory distress syndrome
Amato, M. B. P., Meade, M. O., Slutsky, A. S., Brochard, L., Costa, E. L. V., Schoenfeld, D. A., Stewart, T. E., Briel, M., Talmor, D., Mercat, A., Richard, J. C. M., Carvalho, C. R. R. & Brower, R. G., Feb 19 2014, In: New England Journal of Medicine. 372, 8, p. 747-755 9 p.Research output: Contribution to journal › Article › peer-review
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Mechanical ventilation after lung transplantation: An international survey of practices and preferences
Beer, A., Reed, R. M., Bölükbas, S., Budev, M., Chaux, G., Zamora, M. R., Snell, G., Orens, J. B., Klesney-Tait, J. A., Schmidt, G. A., Brower, R. G. & Eberlein, M., May 2014, In: Annals of the American Thoracic Society. 11, 4, p. 546-553 8 p.Research output: Contribution to journal › Article › peer-review
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Position paper for the organization of extracorporeal membrane oxygenation programs for acute respiratory failure in adult patients
International ECMO Network (ECMONet), Sep 1 2014, In: American journal of respiratory and critical care medicine. 190, 5, p. 488-496 9 p.Research output: Contribution to journal › Article › peer-review
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Rosuvastatin for sepsis-associated acute respiratory distress syndrome
Truwit, J. D., Bernard, G. R., Steingrub, J., Matthay, M. A., Liu, K. D., Albertson, T. E., Brower, R. G., Shanholtz, C., Rock, P., Douglas, I. S., DeBoisblanc, B. P., Hough, C. L., Duncan Hite, R. & Taylor Thompson, B., 2014, In: New England Journal of Medicine. 370, 23, p. 2191-2200 10 p.Research output: Contribution to journal › Article › peer-review
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Targeting normoxemia in acute respiratory distress syndrome may cause worse short-term outcomes because of oxygen toxicity
Aggarwal, N. R. & Brower, R. G., Nov 1 2014, In: Annals of the American Thoracic Society. 11, 9, p. 1449-1453 5 p.Research output: Contribution to journal › Review article › peer-review
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Thank you to Jacob Iasha Sznajder, M.D., editor in chief of the American journal of respiratory and critical care medicine
Finn, P., Brower, R. & Gern, D., Jan 15 2014, In: American journal of respiratory and critical care medicine. 189, 2, 1 p.Research output: Contribution to journal › Editorial › peer-review
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2012
Erratum: The Berlin definition of ARDS: An expanded rationale, justification, and supplementary material (Intensive Care Medicine DOI 10.1007/s00134-012-2682-1)
Ferguson, N. D., Fan, E., Camporota, L., Antonelli, M., Anzueto, A., Beale, R., Brochard, L., Brower, R., Esteban, A., Gattinoni, L., Rhodes, A., Slutsky, A. S., Vincent, J. L., Rubenfeld, G. D., Taylor Thompson, B. & Marco Ranieri, V., Oct 2012, In: Intensive Care Medicine. 38, 10, p. 1731-1732 2 p.Research output: Contribution to journal › Comment/debate › peer-review
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Lung protective mechanical ventilation and two year survival in patients with acute lung injury: Prospective cohort study
Needham, D. M., Colantuoni, E., Mendez-Tellez, P. A., Dinglas, V. D., Sevransky, J. E., Dennison Himmelfarb, C. R., Desai, S. V., Shanholtz, C., Brower, R. G. & Pronovost, P. J., Apr 27 2012, In: BMJ (Online). 344, 7854, e2124.Research output: Contribution to journal › Article › peer-review
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Lung size mismatch in bilateral lung transplantation is associated with allograft function and bronchiolitis obliterans syndrome
Eberlein, M., Permutt, S., Chahla, M. F., Bolukbas, S., Nathan, S. D., Shlobin, O. A., Shelhamer, J. H., Reed, R. M., Pearse, D. B., Orens, J. B. & Brower, R. G., Feb 2012, In: CHEST. 141, 2, p. 451-460 10 p.Research output: Contribution to journal › Article › peer-review
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Neuromuscular electrical stimulation for intensive care unit-acquired weakness: Protocol and methodological implications for a randomized, sham-controlled, phase II trial
Kho, M. E., Truong, A. D., Brower, R. G., Palmer, J. B., Fan, E., Zanni, J. M., Ciesla, N. D., Feldman, D. R., Korupolu, R. & Needham, D. M., Dec 2012, In: Physical therapy. 92, 12, p. 1564-1579 16 p.Research output: Contribution to journal › Article › peer-review
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Parameters of donor-recipient size mismatch and survival after bilateral lung transplantation
Eberlein, M., Reed, R. M., Permutt, S., Chahla, M. F., Bolukbas, S., Nathan, S. D., Iacono, A., Pearse, D. B., Fessler, H. E., Shah, A. S., Orens, J. B. & Brower, R. G., Nov 2012, In: Journal of Heart and Lung Transplantation. 31, 11, p. 1207-1213.e7Research output: Contribution to journal › Article › peer-review
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Point: Should positive end-expiratory pressure in patients with ARDS be set on oxygenation? Yes\No
Miller, R. R., MacIntyre, N. R., Hite, R. D., Truwit, J. D., Brower, R. G., Morris, A. H. & Schmidt, G. A., Jun 2012, In: CHEST. 141, 6, p. 1379-1382 4 p.Research output: Contribution to journal › Editorial › peer-review
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Rebuttal From Dr Miller et al
Russell, M. R., MacIntyre, N. R., Hite, R. D., Truwit, J. D., Brower, R. G. & Morris, A. H., Jun 2012, In: CHEST. 141, 6, p. 1384-1386 3 p.Research output: Contribution to journal › Editorial › peer-review
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Response
Eberlein, M., Reed, R. M., Bolukbas, S., Nathan, S. D. & Brower, R. G., Aug 2012, In: CHEST. 142, 2, 1 p.Research output: Contribution to journal › Letter › peer-review
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The Berlin definition of ARDS: An expanded rationale, justification, and supplementary material
Ferguson, N. D., Fan, E., Camporota, L., Antonelli, M., Anzueto, A., Beale, R., Brochard, L., Brower, R., Esteban, A., Gattinoni, L., Rhodes, A., Slutsky, A. S., Vincent, J. L., Rubenfeld, G. D., Taylor Thompson, B. & Marco Ranieri, V., Oct 2012, In: Intensive Care Medicine. 38, 10, p. 1573-1582 10 p.Research output: Contribution to journal › Article › peer-review
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The effect of lung size mismatch on complications and resource utilization after bilateral lung transplantation
Eberlein, M., Arnaoutakis, G. J., Yarmus, L., Feller-Kopman, D., Dezube, R., Chahla, M. F., Bolukbas, S., Reed, R. M., Klesney-Tait, J., Parekh, K. R., Merlo, C. A., Shah, A. S., Orens, J. B. & Brower, R. G., May 2012, In: Journal of Heart and Lung Transplantation. 31, 5, p. 492-500 9 p.Research output: Contribution to journal › Article › peer-review
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The evolution of eProtocols that enable reproducible clinical research and care methods
Blagev, D. P., Hirshberg, E. L., Sward, K., Thompson, B. T., Brower, R., Truwit, J., Hite, D., Steingrub, J., Orme, J. F., Clemmer, T. P., Weaver, L. K., Thomas, F., Grissom, C. K., Sorenson, D., Sittig, D. F., Wallace, C. J., East, T. D., Warner, H. R. & Morris, A. H., Aug 2012, In: Journal of Clinical Monitoring and Computing. 26, 4, p. 305-317 13 p.Research output: Contribution to journal › Article › peer-review