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  • Harry A Quigley
2020

A method to quantify regional axonal transport blockade at the optic nerve head after short term intraocular pressure elevation in mice

Korneva, A., Schaub, J., Jefferys, J., Kimball, E., Pease, M. E., Nawathe, M., Johnson, T. V., Pitha, I. & Quigley, H., Jul 2020, In : Experimental eye research. 196, 108035.

Research output: Contribution to journalArticle

Open Access

Dasatinib inhibits peripapillary scleral myofibroblast differentiation

Chow, A., McCrea, L., Kimball, E., Schaub, J., Quigley, H. & Pitha, I., May 2020, In : Experimental eye research. 194, 107999.

Research output: Contribution to journalArticle

Peripapillary Scleral Bowing Increases with Age and Is Inversely Associated with Peripapillary Choroidal Thickness in Healthy Eyes

Wang, Y. X., Yang, H., Luo, H., Hong, S. W., Gardiner, S. K., Jeoung, J. W., Hardin, C., Sharpe, G. P., Nouri-Mahdavi, K., Caprioli, J., Demirel, S., Girkin, C. A., Liebmann, J. M., Mardin, C. Y., Quigley, H. A., Scheuerle, A. F., Fortune, B., Chauhan, B. C. & Burgoyne, C. F., Sep 2020, In : American journal of ophthalmology. 217, p. 91-103 13 p.

Research output: Contribution to journalArticle

The effects of glaucoma on the pressure-induced strain response of the human lamina cribrosa

Midgett, D., Liu, B., Ling, Y. T. T., Jefferys, J. L., Quigley, H. A. & Nguyen, T. D., Apr 2020, In : Investigative Ophthalmology and Visual Science. 61, 4, 41.

Research output: Contribution to journalArticle

Open Access

The Histology of Human Glaucoma Cupping and Optic Nerve Damage: Clinicopathologic Correlation in 21 Eyes

Quigley, H. A. & Green, W. R., Apr 2020, In : Ophthalmology. 127, 4, p. S45-S69

Research output: Contribution to journalArticle

Open Access

The inflation response of the human lamina cribrosa and sclera: Analysis of deformation and interaction

Midgett, D. E., Jefferys, J. L., Quigley, H. A. & Nguyen, T. D., Apr 1 2020, In : Acta Biomaterialia. 106, p. 225-241 17 p.

Research output: Contribution to journalArticle

Toward a new definition of glaucomatous optic neuropathy for clinical research

Iyer, J., Vianna, J. R., Chauhan, B. C. & Quigley, H. A., Mar 1 2020, In : Current opinion in ophthalmology. 31, 2, p. 85-90 6 p.

Research output: Contribution to journalReview article

2019

Characterizing the collagen network structure and pressure-induced strains of the human lamina cribrosa

Ling, Y. T. T., Shi, R., Midgett, D. E., Jefferys, J. L., Quigley, H. A. & Nguyen, T. D., Jun 2019, In : Investigative Ophthalmology and Visual Science. 60, 7, p. 2406-2422 17 p.

Research output: Contribution to journalArticle

Open Access

Factors influencing optical coherence tomography peripapillary choroidal thickness: A multicenter study

Yang, H., Luo, H., Gardiner, S. K., Hardin, C., Sharpe, G. P., Caprioli, J., Demirel, S., Girkin, C. A., Liebmann, J. M., Mardin, C. Y., Quigley, H. A., Scheuerle, A. F., Fortune, B., Chauhan, B. C. & Burgoyne, C. F., Feb 2019, In : Investigative Ophthalmology and Visual Science. 60, 2, p. 795-806 12 p.

Research output: Contribution to journalArticle

Open Access

OCT-Detected Optic Nerve Head Neural Canal Direction, Obliqueness, and Minimum Cross-Sectional Area in Healthy Eyes

Hong, S., Yang, H., Gardiner, S. K., Luo, H., Hardin, C., Sharpe, G. P., Caprioli, J., Demirel, S., Girkin, C. A., Liebmann, J. M., Mardin, C. Y., Quigley, H. A., Scheuerle, A. F., Fortune, B., Chauhan, B. C. & Burgoyne, C. F., Dec 2019, In : American journal of ophthalmology. 208, p. 185-205 21 p.

Research output: Contribution to journalArticle

Open Access

Quantification of collagen fiber structure using second harmonic generation imaging and two-dimensional discrete Fourier transform analysis: Application to the human optic nerve head

Pijanka, J. K., Markov, P. P., Midgett, D., Paterson, N. G., White, N., Blain, E. J., Nguyen, T. D., Quigley, H. A. & Boote, C., 2019, (Accepted/In press) In : Journal of biophotonics. e201800376.

Research output: Contribution to journalArticle

2018

21st century glaucoma care

Quigley, H. A., Jan 1 2018, (Accepted/In press) In : Eye (Basingstoke).

Research output: Contribution to journalArticle

Age-Related Changes in Quantitative Strain of Mouse Astrocytic Lamina Cribrosa and Peripapillary Sclera Using Confocal Microscopy in an Explant Model

Nguyen, C., Midgett, D., Kimball, E., Jefferys, J., Nguyen, T. D., Schaub, J., Pease, M. E. & Quigley, H. A., Oct 1 2018, In : Investigative ophthalmology & visual science. 59, 12, p. 5157-5166 10 p.

Research output: Contribution to journalArticle

A Protective Eye Shield Reduces Limbal Strain and Its Variability during Simulated Sleep in Adults with Glaucoma

Flatau, A., Solano, F., Jefferys, J. L., Damion, C. & Quigley, H. A., Jan 1 2018, In : Journal of Glaucoma. 27, 1, p. 77-86 10 p.

Research output: Contribution to journalArticle

Evaluation of automated segmentation algorithms for optic nerve head structures in optical coherence tomography images

Duan, X. J., Jefferys, J. L. & Quigley, H. A., Aug 1 2018, In : Investigative Ophthalmology and Visual Science. 59, 10, p. 3816-3826 11 p.

Research output: Contribution to journalArticle

Factors influencing central lamina cribrosa depth: A multicenter study

Luo, H., Yang, H., Gardiner, S. K., Hardin, C., Sharpe, G. P., Caprioli, J., Demirel, S., Girkin, C. A., Liebmann, J. M., Mardin, C. Y., Quigley, H. A., Scheuerle, A. F., Fortune, B., Chauhan, B. C. & Burgoyne, C. F., May 2018, In : Investigative Ophthalmology and Visual Science. 59, 6, p. 2357-2370 14 p.

Research output: Contribution to journalArticle

Improved Outcomes for Transscleral Cyclophotocoagulation Through Optimized Treatment Parameters

Quigley, H. A., Jun 18 2018, (Accepted/In press) In : Journal of Glaucoma.

Research output: Contribution to journalArticle

Protruded retinal layers within the optic nerve head neuroretinal rim

Torres, L. A., Vianna, J. R., Jarrar, F., Sharpe, G. P., Araie, M., Caprioli, J., Demirel, S., Girkin, C. A., Hangai, M., Iwase, A., Liebmann, J. M., Mardin, C. Y., Nakazawa, T., Quigley, H. A., Scheuerle, A. F., Sugiyama, K., Tanihara, H., Tomita, G., Yanagi, Y., Burgoyne, C. F. & 1 others, Chauhan, B. C., Jun 2018, In : Acta Ophthalmologica. 96, 4, p. e493-e502

Research output: Contribution to journalArticle

Sustained dorzolamide release prevents axonal and retinal ganglion cell loss in a rat model of IOP-glaucoma

Pitha, I., Kimball, E. C., Oglesby, E. N., Pease, M. E., Fu, J., Schaub, J., Kim, Y. C., Hu, Q., Hanes, J. S. & Quigley, H. A., Mar 1 2018, In : Translational Vision Science and Technology. 7, 2, 13.

Research output: Contribution to journalArticle

The Contribution of Sulfated Glycosaminoglycans to the Inflation Response of the Human Optic Nerve Head

Midgett, D. E., Jefferys, J. L., Quigley, H. A. & Nguyen, T. D., Jun 1 2018, In : Investigative ophthalmology & visual science. 59, 7, p. 3144-3154 11 p.

Research output: Contribution to journalArticle

The effects of age on mitochondria, axonal transport, and axonal degeneration after chronic IOP elevation using a murine ocular explant model

Kimball, E. C., Jefferys, J. L., Pease, M. E., Oglesby, E. N., Nguyen, C., Schaub, J., Pitha, I. & Quigley, H. A., Jul 1 2018, In : Experimental Eye Research. 172, p. 78-85 8 p.

Research output: Contribution to journalArticle

Use of animal models and techniques in glaucoma research: Introduction

Quigley, H. A., Jan 1 2018, Methods in Molecular Biology. Humana Press Inc., Vol. 1695. p. 1-10 10 p. (Methods in Molecular Biology; vol. 1695).

Research output: Chapter in Book/Report/Conference proceedingChapter

Use of Optical Coherence Tomography by Nonexpert Personnel as a Screening Approach for Glaucoma

Liu, M. M., Cho, C., Jefferys, J. L., Quigley, H. A. & Scott, A., Jan 1 2018, In : Journal of Glaucoma. 27, 1, p. 64-70 7 p.

Research output: Contribution to journalArticle

2017

Biomechanical responses of lamina cribrosa to intraocular pressure change assessed by optical coherence tomography in glaucoma eyes

Quigley, H., Arora, K., Idrees, S., Solano, F., Bedrood, S., Lee, C., Jefferys, J. & Nguyen, T. D., May 2017, In : Investigative Ophthalmology and Visual Science. 58, 5, p. 2566-2577 12 p.

Research output: Contribution to journalArticle

Global causes of blindness and distance vision impairment 1990–2020: a systematic review and meta-analysis

Flaxman, S. R., Bourne, R. R. A., Resnikoff, S., Ackland, P., Braithwaite, T., Cicinelli, M. V., Das, A., Jonas, J. B., Keeffe, J., Kempen, J. H., Leasher, J., Limburg, H., Naidoo, K., Pesudovs, K., Silvester, A., Stevens, G. A., Tahhan, N., Wong, T. Y., Taylor, H. R., Arditi, A. & 79 others, Barkana, Y., Bozkurt, B., Bron, A., Budenz, D., Cai, F., Casson, R., Chakravarthy, U., Choi, J., Congdon, N., Dana, R., Dandona, R., Dandona, L., Dekaris, I., Del Monte, M., Deva, J., Dreer, L., Ellwein, L., Frazier, M., Frick, K., Friedman, D., Furtado, J., Gao, H., Gazzard, G., George, R., Gichuhi, S., Gonzalez, V., Hammond, B., Hartnett, M. E., He, M., Hejtmancik, J., Hirai, F., Huang, J., Ingram, A., Javitt, J., Joslin, C., Khairallah, M., Khanna, R., Kim, J., Lambrou, G., Lansingh, V. C., Lanzetta, P., Lim, J., Mansouri, K., Mathew, A., Morse, A., Munoz, B., Musch, D., Nangia, V., Palaiou, M., Parodi, M. B., Pena, F. Y., Peto, T., Quigley, H., Raju, M., Ramulu, P., Reza, D., Robin, A., Rossetti, L., Saaddine, J., Sandar, M., Serle, J., Shen, T., Shetty, R., Sieving, P., Silva, J. C., Sitorus, R. S., Stambolian, D., Tejedor, J., Tielsch, J., Tsilimbaris, M., van Meurs, J., Varma, R., Virgili, G., Wang, Y. X., Wang, N. L., West, S., Wiedemann, P., Wormald, R. & Zheng, Y., Dec 1 2017, In : The Lancet Global Health. 5, 12, p. e1221-e1234

Research output: Contribution to journalArticle

Magnitude, temporal trends, and projections of the global prevalence of blindness and distance and near vision impairment: a systematic review and meta-analysis

Bourne, R. R. A., Flaxman, S. R., Braithwaite, T., Cicinelli, M. V., Das, A., Jonas, J. B., Keeffe, J., Kempen, J. H., Leasher, J., Limburg, H., Naidoo, K., Pesudovs, K., Resnikoff, S., Silvester, A., Stevens, G. A., Tahhan, N., Wong, T. Y., Taylor, H. R., Ackland, P., Arditi, A. & 79 others, Barkana, Y., Bozkurt, B., Wormald, R., Bron, A., Budenz, D., Cai, F., Casson, R., Chakravarthy, U., Congdon, N., Peto, T., Choi, J., Dana, R., Palaiou, M., Dandona, R., Dandona, L., Shen, T., Dekaris, I., Del Monte, M., Deva, J., Dreer, L., Frazier, M., Ellwein, L., Hejtmancik, J., Frick, K., Friedman, D., Javitt, J., Munoz, B., Quigley, H., Ramulu, P., Robin, A., Tielsch, J., West, S., Furtado, J., Gao, H., Gazzard, G., George, R., Gichuhi, S., Gonzalez, V., Hammond, B., Hartnett, M. E., He, M., Hirai, F., Huang, J., Ingram, A., Joslin, C., Khanna, R., Stambolian, D., Khairallah, M., Kim, J., Lambrou, G., Lansingh, V. C., Lanzetta, P., Lim, J., Mansouri, K., Mathew, A., Morse, A., Musch, D., Nangia, V., Battaglia, M., Yaacov, F., Raju, M., Rossetti, L., Saaddine, J., Sandar, M., Serle, J., Shetty, R., Sieving, P., Silva, J. C., Sitorus, R. S., Tejedor, J., Tsilimbaris, M., van Meurs, J., Varma, R., Virgili, G., Volmink, J., Xing, Y., Wang, N. L., Wiedemann, P. & Zheng, Y., Sep 1 2017, In : The Lancet Global Health. 5, 9, p. e888-e897

Research output: Contribution to journalArticle

Measuring deformation in the mouse optic nerve head and peripapillary sclera

Nguyen, C., Midgett, D., Kimball, E. C., Steinhart, M. R., Nguyen, T. D., Pease, M. E., Oglesby, E. N., Jefferys, J. L. & Quigley, H. A., Feb 1 2017, In : Investigative Ophthalmology and Visual Science. 58, 2, p. 721-733 13 p.

Research output: Contribution to journalArticle

Regional Retinal Ganglion Cell Axon Loss in a Murine Glaucoma Model

Schaub, J. A., Kimball, E. C., Steinhart, M. R., Nguyen, C., Pease, M. E., Oglesby, E. N., Jefferys, J. L. & Quigley, H. A., May 1 2017, In : Investigative ophthalmology & visual science. 58, 5, p. 2765-2773 9 p.

Research output: Contribution to journalArticle

Regional variations in the mechanical strains of the human optic nerve head

Midgett, D. E., Pease, M. E., Quigley, H. A., Patel, M., Franck, C. & Nguyen, T. D., 2017, Mechanics of Biological Systems and Materials - Proceedings of the 2016 Annual Conference on Experimental and Applied Mechanics. Springer New York LLC, Vol. 6. p. 119-127 9 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

The Effect of Change in Intraocular Pressure on Choroidal Structure in Glaucomatous Eyes

Zhang, X., Cole, E., Pillar, A., Lane, M., Waheed, N., Adhi, M., Magder, L., Quigley, H. A. & Saeedi, O., Jun 1 2017, In : Investigative ophthalmology & visual science. 58, 7, p. 3278-3285 8 p.

Research output: Contribution to journalArticle

2016

Adherence with the use of target intraocular pressure for glaucoma patients in a large university practice

Solano-Moncada, F., Dymerska, M., Jefferys, J. L. & Quigley, H. A., Jan 1 2016, In : Journal of glaucoma. 25, 4, p. e424-e432

Research output: Contribution to journalArticle

Changes in Anterior Segment Morphology and Predictors of Angle Widening after Laser Iridotomy in South Indian Eyes

Zebardast, N., Kavitha, S., Krishnamurthy, P., Friedman, D. S., Nongpiur, M. E., Aung, T., Quigley, H. A., Ramulu, P. Y. & Venkatesh, R., Dec 1 2016, In : Ophthalmology. 123, 12, p. 2519-2526 8 p.

Research output: Contribution to journalArticle

Inflation test of the human optic nerve head using digital volume correlation

Midgett, D. E., Quigley, H. A., Pease, M. E., Franck, C., Toyjanova, J. & Nguyen, T. D., Jan 1 2016, Mechanics of Biological Systems and Materials - Proceedings of the 2015 Annual Conference on Experimental and Applied Mechanics. Korach, C. S., Tekalur, S. A. & Zavattieri, P. (eds.). Springer New York LLC, p. 7-15 9 p. (Conference Proceedings of the Society for Experimental Mechanics Series; vol. 6).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Measured changes in limbal strain during simulated sleep in face down position using an instrumented contact lens in healthy adults and adults with glaucoma

Flatau, A., Solano, F., Idrees, S., Jefferys, J. L., Volpe, P., Damion, C. & Quigley, H. A., Apr 1 2016, In : JAMA Ophthalmology. 134, 4, p. 375-382 8 p.

Research output: Contribution to journalArticle

Neuroprotection for glaucoma: Requirements for clinical translation

Levin, L. A., Crowe, M. E. & Quigley, H. A., Mar 28 2016, (Accepted/In press) In : Experimental Eye Research.

Research output: Contribution to journalArticle

Scleral fibroblast response to experimental glaucoma in mice

Oglesby, E. N., Tezel, G., Cone-Kimball, E., Steinhart, M. R., Jefferys, J., Pease, M. E. & Quigley, H. A., Jan 29 2016, In : Molecular vision. 22, p. 82-99 18 p.

Research output: Contribution to journalArticle

Subconjunctival delivery of dorzolamide-loaded poly(ether-anhydride) microparticles produces sustained lowering of intraocular pressure in rabbits

Fu, J., Sun, F., Liu, W., Liu, Y., Gedam, M., Hu, Q., Fridley, C., Quigley, H. A., Hanes, J. S. & Pitha, I., Sep 6 2016, In : Molecular Pharmaceutics. 13, 9, p. 2987-2995 9 p.

Research output: Contribution to journalArticle

The contribution of glycosaminoglycans to the mechanical behaviour of the posterior human sclera

Murienne, B. J., Chen, M. L., Quigley, H. A. & Nguyen, T. D., Jun 1 2016, In : Journal of the Royal Society Interface. 13, 119, 20160367.

Research output: Contribution to journalArticle

The pressure-induced deformation response of the human lamina cribrosa: Analysis of regional variations

Midgett, D. E., Pease, M. E., Jefferys, J. L., Patel, M., Franck, C., Quigley, H. A. & Nguyen, T. D., Jul 25 2016, (Accepted/In press) In : Acta Biomaterialia.

Research output: Contribution to journalArticle

Time-lapse retinal ganglion cell dendritic field degeneration imaged in organotypic retinal explant culture

Johnson, T. V., Oglesby, E. N., Steinhart, M. R., Cone-Kimball, E., Jefferys, J. & Quigley, H. A., Jan 1 2016, In : Investigative Ophthalmology and Visual Science. 57, 1, p. 253-264 12 p.

Research output: Contribution to journalArticle

Unilateral glaucoma associated with conjunctival Angioma and choroidal thickening without facial Angioma

Saeedi, O. J., Chang, L. Y., Arora, K. S., Jampel, H. D. & Quigley, H. A., Jul 1 2016, In : Middle East African Journal of Ophthalmology. 23, 3, p. 280-282 3 p.

Research output: Contribution to journalArticle

2014

Change in choroidal thickness and axial length with change in intraocular pressure after trabeculectomy

Saeedi, O., Pillar, A., Jefferys, J., Arora, K., Friedman, D. & Quigley, H., Jul 2014, In : British Journal of Ophthalmology. 98, 7, p. 976-979 4 p.

Research output: Contribution to journalArticle

Changes in scleral collagen organization in murine chronic experimental glaucoma

Pijanka, J. K., Kimball, E. C., Pease, M. E., Abass, A., Sorensen, T., Nguyen, T. D., Quigley, H. A. & Boote, C., Jan 1 2014, In : Investigative ophthalmology & visual science. 55, 10, p. 6554-6564 11 p.

Research output: Contribution to journalArticle