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  • Alan Wayne Partin
2020

Assessment of high-grade prostate cancer risk using prostate cancer biomarkers

Stanton, W. N., Crawford, E. D., Arangua, P. B., La Rosa, F. G., van Bokhoven, A., Lucia, M. S., Poage, W. L., Partin, A., Maroni, P. & Werahera, P. N., Feb 1 2020, In : The Canadian journal of urology. 27, 1, p. 10080-10085 6 p.

Research output: Contribution to journalArticle

T-Cell Infiltration and Adaptive Treg Resistance in Response to Androgen Deprivation With or Without Vaccination in Localized Prostate Cancer

Obradovic, A. Z., Dallos, M. C., Zahurak, M. L., Partin, A. W., Schaeffer, E. M., Ross, A. E., Allaf, M. E., Nirschl, T. R., Liu, D., Chapman, C. G., O'Neal, T., Cao, H., Durham, J. N., Guner, G., Baena-Del Valle, J. A., Ertunc, O., De Marzo, A. M., Antonarakis, E. S. & Drake, C. G., Jul 1 2020, In : Clinical cancer research : an official journal of the American Association for Cancer Research. 26, 13, p. 3182-3192 11 p.

Research output: Contribution to journalArticle

2019

A Phase I Study to Assess the Safety and Cancer-Homing Ability of Allogeneic Bone Marrow-Derived Mesenchymal Stem Cells in Men with Localized Prostate Cancer

Schweizer, M. T., Wang, H., Bivalacqua, T. J., Partin, A. W., Lim, S. J., Chapman, C., Abdallah, R., Levy, O., Bhowmick, N. A., Karp, J. M., De Marzo, A., Isaacs, J. T., Brennen, W. N. & Denmeade, S. R., May 2019, In : Stem Cells Translational Medicine. 8, 5, p. 441-449 9 p.

Research output: Contribution to journalArticle

Open Access

Clinical Validation of IsoPSA™, a Single Parameter, Structure Based Assay for Improved Detection of High Grade Prostate Cancer

Stovsky, M., Klein, E. A., Chait, A., Manickam, K., Stephenson, A. J., Wagner, M., Dineen, M., Lotan, Y., Partin, A. W., Baniel, J., Kestranek, A., Gawande, P. & Boris Zaslavsky, Z., Jun 1 2019, In : The Journal of urology. 201, 6, p. 1115-1120 6 p.

Research output: Contribution to journalArticle

In Reply

Brennen, W. N., Schweizer, M. T., Wang, H., Bivalacqua, T. J., Partin, A. W., Lim, S. J., Chapman, C., Abdallah, R., Levy, O., Bhowmick, N. A., Karp, J. M., De Marzo, A., Isaacs, J. T. & Denmeade, S. R., Jul 2019, In : Stem Cells Translational Medicine. 8, 7, p. 739-740 2 p.

Research output: Contribution to journalLetter

Open Access
2018

Adjuvant radiation with androgen-deprivation therapy for men with lymph node metastases after radical prostatectomy: Identifying men who benefit

Gupta, M., Patel, H. D., Schwen, Z. R., Tran, P. T. & Partin, A. W., Jan 1 2018, (Accepted/In press) In : BJU International.

Research output: Contribution to journalArticle

A Prospective Adaptive Utility Trial to Validate Performance of a Novel Urine Exosome Gene Expression Assay to Predict High-grade Prostate Cancer in Patients with Prostate-specific Antigen 2–10 ng/ml at Initial Biopsy

McKiernan, J., Donovan, M. J., Margolis, E., Partin, A., Carter, B., Brown, G., Torkler, P., Noerholm, M., Skog, J., Shore, N., Andriole, G., Thompson, I. & Carroll, P., Dec 2018, In : European Urology. 74, 6, p. 731-738 8 p.

Research output: Contribution to journalArticle

Combining Prostate Health Index density, magnetic resonance imaging and prior negative biopsy status to improve the detection of clinically significant prostate cancer

Druskin, S. C., Tosoian, J. J., Young, A., Collica, S., Srivastava, A., Ghabili, K., Macura, K. J., Carter, H. B., Partin, A. W., Sokoll, L. J., Ross, A. E. & Pavlovich, C. P., Apr 2018, In : BJU International. 121, 4, p. 619-626 8 p.

Research output: Contribution to journalArticle

Initial Experience Performing In-office Ultrasound-guided Transperineal Prostate Biopsy Under Local Anesthesia Using the PrecisionPoint Transperineal Access System

Meyer, A. R., Joice, G. A., Schwen, Z. R., Partin, A. W., Allaf, M. E. & Gorin, M., Jan 1 2018, (Accepted/In press) In : Urology.

Research output: Contribution to journalArticle

Profiling the Urinary Microbiome in Men with Positive versus Negative Biopsies for Prostate Cancer

Shrestha, E., White, J. R., Yu, S. H., Kulac, I., Ertunc, O., Demarzo, A. M., Yegnasubramanian, S., Mangold, L. A., Partin, A. W. & Sfanos, K., Jan 1 2018, In : Journal of Urology. 199, 1, p. 161-171 11 p.

Research output: Contribution to journalArticle

Subtyping the Risk of Intermediate Risk Prostate Cancer for Active Surveillance Based on Adverse Pathology at Radical Prostatectomy

Patel, H. D., Gupta, M., Tosoian, J. J., Carter, H. B., Partin, A. W. & Epstein, J. I., Jan 1 2018, (Accepted/In press) In : Journal of Urology.

Research output: Contribution to journalArticle

2016

An Approach Using PSA Levels of 1.5 ng/mL as the Cutoff for Prostate Cancer Screening in Primary Care

Crawford, E. D., Rosenberg, M. T., Partin, A. W., Cooperberg, M. R., Maccini, M., Loeb, S., Pettaway, C. A., Shore, N. D., Arangua, P., Hoenemeyer, J., Leveridge, M., Leapman, M., Pinto, P., Thompson, I. M., Carroll, P., Eastham, J., Gomella, L. & Klein, E. A., Oct 1 2016, In : Urology. 96, p. 116-120 5 p.

Research output: Contribution to journalArticle

A Novel Approach for Performing Bone Marrow Aspiration at the Time of Radical Prostatectomy

Tosoian, J. J., Reyes, D. K., Gorin, M. A., Hortopan, S., Partin, A. W., Pienta, K. J., Ross, A. E. & Schaeffer, E. M., May 1 2016, In : Urology Case Reports. 6, p. 45-46 2 p.

Research output: Contribution to journalArticle

A novel urine exosome gene expression assay to predict high-grade prostate cancer at initial biopsy

McKiernan, J., Donovan, M. J., O'Neill, V., Bentink, S., Noerholm, M., Belzer, S., Skog, J., Kattan, M. W., Partin, A., Andriole, G., Brown, G., Wei, J. T., Thompson, I. M. & Carroll, P., Jul 2016, In : JAMA Oncology. 2, 7, p. 882-889 8 p.

Research output: Contribution to journalArticle

Clinical prospects of long noncoding RNAs as novel biomarkers and therapeutic targets in prostate cancer

Mouraviev, V., Lee, B., Patel, V., Albala, D., Johansen, T. E. B., Partin, A., Ross, A. & Perera, R. J., Mar 1 2016, In : Prostate Cancer and Prostatic Diseases. 19, 1, p. 14-20 7 p.

Research output: Contribution to journalReview article

Clinical validation of the 2005 isup gleason grading system in a cohort of intermediate and high risk men undergoing radical prostatectomy

Faraj, S. F., Bezerra, S. M., Yousefi, K., Fedor, H., Glavaris, S., Han, M., Partin, A. W., Humphreys, E., Tosoian, J., Johnson, M. H., Davicioni, E., Trock, B. J., Schaeffer, E. M., Ross, A. E. & Netto, G. J., Jan 5 2016, In : PloS one. 11, 1, e0146189.

Research output: Contribution to journalArticle

From the Editors

Partin, A. & Wein, A., Jan 1 2016, In : Urology Case Reports. 4, 1 p.

Research output: Contribution to journalEditorial

Germline Mutations in ATM and BRCA1/2 Distinguish Risk for Lethal and Indolent Prostate Cancer and are Associated with Early Age at Death

Na, R., Zheng, S. L., Han, M., Yu, H., Jiang, D., Shah, S., Ewing, C. M., Zhang, L., Novakovic, K., Petkewicz, J., Gulukota, K., Helseth, D. L., Quinn, M., Humphries, E., Wiley, K. E., Isaacs, S. D., Wu, Y., Liu, X., Zhang, N., Wang, C. H. & 17 others, Khandekar, J., Hulick, P. J., Shevrin, D. H., Cooney, K. A., Shen, Z., Partin, A. W., Carter, H. B., Carducci, M. A., Eisenberger, M., Denmeade, S. R., McGuire, M., Walsh, P., Helfand, B. T., Brendler, C. B., Ding, Q., Xu, J. & Isaacs, W. B., 2016, (Accepted/In press) In : European Urology.

Research output: Contribution to journalArticle

New Prostate Cancer Grading System Predicts Long-term Survival Following Surgery for Gleason Score 8-10 Prostate Cancer

Ham, W. S., Chalfin, H. J., Feng, Z., Trock, B., Epstein, J. I., Cheung, C., Humphreys, E., Partin, A. W. & Han, M., 2016, (Accepted/In press) In : European Urology.

Research output: Contribution to journalArticle

Patterns of Pelvic Lymph Node Dissection at the Time of Radical Prostatectomy for Low-risk Men

Chalfin, H. J., Feng, Z., Trock, B. & Partin, A. W., Oct 13 2016, (Accepted/In press) In : Urology.

Research output: Contribution to journalArticle

Prostate Health Index (PHI) Predicts High-stage Pathology in African American Men

Schwen, Z. R., Tosoian, J. J., Sokoll, L. J., Mangold, L., Humphreys, E., Schaeffer, E. M., Partin, A. W. & Ross, A. E., Apr 1 2016, In : Urology. 90, p. 136-140 5 p.

Research output: Contribution to journalArticle

Prostate Health Index improves multivariable risk prediction of aggressive prostate cancer

Loeb, S., Shin, S. S., Broyles, D. L., Wei, J. T., Sanda, M., Klee, G., Partin, A. W., Sokoll, L. J., Chan, D. W-Y., Bangma, C. H., van Schaik, R. H. N., Slawin, K. M., Marks, L. S. & Catalona, W. J., 2016, (Accepted/In press) In : BJU International.

Research output: Contribution to journalArticle

Risk score predicts high-grade prostate cancer in DNA-methylation positive, histopathologically negative biopsies

Van Neste, L., Partin, A. W., Stewart, G. D., Epstein, J. I., Harrison, D. J. & Van Criekinge, W., Sep 1 2016, In : Prostate. 76, 12, p. 1078-1087 10 p.

Research output: Contribution to journalArticle

Role of biobanking in urology: A review

Chalfin, H. J., Fabian, E., Mangold, L., Yeater, D. B., Pienta, K. & Partin, A. W., 2016, (Accepted/In press) In : BJU International.

Research output: Contribution to journalArticle

SPINK1 Defines a Molecular Subtype of Prostate Cancer in Men with More Rapid Progression in an at Risk, Natural History Radical Prostatectomy Cohort

Johnson, M. H., Ross, A. E., Alshalalfa, M., Erho, N., Yousefi, K., Glavaris, S., Fedor, H., Han, M., Faraj, S. F., Bezerra, S. M., Netto, G. J., Partin, A. W., Trock, B. J., Davicioni, E. & Schaeffer, E. M., Nov 1 2016, In : Journal of Urology. 196, 5, p. 1436-1444 9 p.

Research output: Contribution to journalArticle

Tissue-based Genomics Augments Post-prostatectomy Risk Stratification in a Natural History Cohort of Intermediate- and High-Risk Men

Ross, A. E., Johnson, M. H., Yousefi, K., Davicioni, E., Netto, G. J., Marchionni, L., Fedor, H. L., Glavaris, S., Choeurng, V., Buerki, C., Erho, N., Lam, L. L., Humphreys, E. B., Faraj, S., Bezerra, S. M., Han, M., Partin, A. W., Trock, B. J. & Schaeffer, E. M., Jan 1 2016, In : European Urology. 69, 1, p. 157-165 9 p.

Research output: Contribution to journalArticle

Urinary Biomarkers for Prostate Cancer

Tosoian, J. J., Ross, A. E., Sokoll, L. J., Partin, A. W. & Pavlovich, C. P., Feb 1 2016, In : Urologic Clinics of North America. 43, 1, p. 17-38 22 p.

Research output: Contribution to journalReview article

Utility of Risk Models in Decision Making after Radical Prostatectomy: Lessons from a Natural History Cohort of Intermediate- and High-Risk Men

Ross, A. E., Yousefi, K., Davicioni, E., Ghadessi, M., Johnson, M. H., Sundi, D., Tosoian, J. J., Han, M., Humphreys, E. B., Partin, A. W., Walsh, P. C., Trock, B. J. & Schaeffer, E. M., Mar 1 2016, In : European Urology. 69, 3, p. 496-504 9 p.

Research output: Contribution to journalArticle

2015

18F-DCFBC PET/CT for PSMA-based detection and characterization of primary prostate cancer

Rowe, S. P., Gage, K. L., Faraj, S. F., Macura, K. J., Cornish, T. C., Gonzalez-Roibon, N., Guner, G., Munari, E., Partin, A. W., Pavlovich, C. P., Han, M., Carter, H. B., Bivalacqua, T. J., Blackford, A., Holt, D., Dannals, R. F., Netto, G. J., Lodge, M. A., Mease, R. C., Pomper, M. G. & 1 others, Cho, S. Y., Jul 1 2015, In : Journal of Nuclear Medicine. 56, 7, p. 1003-1010 8 p.

Research output: Contribution to journalArticle

Evaluation of two mitochondrial DNA biomarkers for prostate cancer detection

Maragh, S., Veltri, R. W., Lund, S. P., Mangold, L., Isharwal, S., Christudass, C. S., Partin, A. W., Humphreys, E. B., Sorbara, L., Srivastava, S. & Wagner, P. D., Nov 24 2015, In : Cancer Biomarkers. 15, 6, p. 763-773 11 p.

Research output: Contribution to journalArticle

Is clinical stage T2c prostate cancer an intermediate- or high-risk disease?

Klaassen, Z., Singh, A. A., Howard, L. E., Feng, Z., Trock, B., Terris, M. K., Aronson, W. J., Cooperberg, M. R., Amling, C. L., Kane, C. J., Partin, A., Han, M. & Freedland, S. J., May 1 2015, In : Cancer. 121, 9, p. 1414-1421 8 p.

Research output: Contribution to journalArticle

Risk Factors for Intraprostatic Incision into Malignant Glands at Radical Prostatectomy

Park, S. W., Readal, N., Jeong, B. C., Humphreys, E. B., Epstein, J. I., Partin, A. W. & Han, M., Aug 1 2015, In : European Urology. 68, 2, p. 311-316 6 p.

Research output: Contribution to journalArticle

Testosterone and prostate cancer: An evidence-based review of pathogenesis and oncologic risk

Michaud, J. E., Billups, K. L. & Partin, A. W., Dec 2015, In : Therapeutic Advances in Urology. 7, 6, p. 378-387 10 p.

Research output: Contribution to journalReview article

The prostate health index selectively identifies clinically significant prostate cancer

Loeb, S., Sanda, M. G., Broyles, D. L., Shin, S. S., Bangma, C. H., Wei, J. T., Partin, A. W., Klee, G. G., Slawin, K. M., Marks, L. S., Van Schaik, R. H. N., Chan, D. W., Sokoll, L. J., Cruz, A. B., Mizrahi, I. A. & Catalona, W. J., Apr 1 2015, In : Journal of Urology. 193, 4, p. 1163-1169 7 p.

Research output: Contribution to journalArticle

The relationship between the extent of extraprostatic extension and survival following radical prostatectomy

Jeong, B. C., Chalfin, H. J., Lee, S. B., Feng, Z., Epstein, J. I., Trock, B. J., Partin, A. W., Humphreys, E., Walsh, P. C. & Han, M., Feb 1 2015, In : European Urology. 67, 2, p. 342-346 5 p.

Research output: Contribution to journalArticle

2014

Allogeneic versus autologous blood transfusion and survival after radical prostatectomy

Chalfin, H. J., Frank, S. M., Feng, Z., Trock, B. J., Drake, C. G., Partin, A. W., Humphreys, E., Ness, P. M., Jeong, B. C., Lee, S. B. & Han, M., Jan 1 2014, In : Transfusion. 54, 9, p. 2168-2174 7 p.

Research output: Contribution to journalArticle

A meta-analysis of 87,040 individuals identifies 23 new susceptibility loci for prostate cancer

Olama, A. A. A., Kote-Jarai, Z., Berndt, S. I., Conti, D. V., Schumacher, F., Han, Y., Benlloch, S., Hazelett, D. J., Wang, Z., Saunders, E., Leongamornlert, D., Lindstrom, S., Jugurnauth-Little, S., Dadaev, T., Tymrakiewicz, M., Stram, D. O., Rand, K., Wan, P., Stram, A., Sheng, X. & 144 others, Pooler, L. C., Park, K., Xia, L., Tyrer, J., Kolonel, L. N., Marchand, L. L., Hoover, R. N., Machiela, M. J., Yeager, M., Burdette, L., Chung, C. C., Hutchinson, A., Yu, K., Goh, C., Ahmed, M., Govindasami, K., Guy, M., Tammela, T. L. J., Auvinen, A., Wahlfors, T., Schleutker, J., Visakorpi, T., Leinonen, K. A., Xu, J., Aly, M., Donovan, J., Travis, R. C., Key, T. J., Siddiq, A., Canzian, F., Khaw, K. T., Takahashi, A., Kubo, M., Pharoah, P., Pashayan, N., Weischer, M., Nordestgaard, B. G., Nielsen, S. F., Klarskov, P., Røder, M. A., Iversen, P., Thibodeau, S. N., McDonnell, S. K., Schaid, D. J., Stanford, J. L., Kolb, S., Holt, S., Knudsen, B., Coll, A. H., Gapstur, S. M., Diver, W. R., Stevens, V. L., Maier, C., Luedeke, M., Herkommer, K., Rinckleb, A. E., Strom, S. S., Pettaway, C., Yeboah, E. D., Tettey, Y., Biritwum, R. B., Adjei, A. A., Tay, E., Truelove, A., Niwa, S., Chokkalingam, A. P., Cannon-Albright, L., Cybulski, C., Wokołorczyk, D., Kluźniak, W., Park, J., Sellers, T., Lin, H. Y., Isaacs, W. B., Partin, A. W., Brenner, H., Dieffenbach, A. K., Stegmaier, C., Chen, C., Giovannucci, E. L., Ma, J., Stampfer, M., Penney, K. L., Mucci, L., John, E. M., Ingles, S. A., Kittles, R. A., Murphy, A. B., Pandha, H., Michael, A., Kierzek, A. M., Blot, W., Signorello, L. B., Zheng, W., Albanes, D., Virtamo, J., Weinstein, S., Nemesure, B., Carpten, J., Leske, C., Wu, S. Y., Hennis, A., Kibel, A. S., Rybicki, B. A., Neslund-Dudas, C., Hsing, A. W., Chu, L., Goodman, P. J., Klein, E. A., Zheng, S. L., Batra, J., Clements, J., Spurdle, A., Teixeira, M. R., Paulo, P., Maia, S., Slavov, C., Kaneva, R., Mitev, V., Witte, J. S., Casey, G., Gillanders, E. M., Seminara, D., Riboli, E., Hamdy, F. C., Coetzee, G. A., Li, Q., Freedman, M. L., Hunter, D. J., Muir, K., Gronberg, H., Neal, D. E., Southey, M., Giles, G. G., Severi, G., Cook, M. B., Nakagawa, H., Wiklund, F., Kraft, P., Chanock, S. J., Henderson, B. E., Easton, D. F., Eeles, R. A. & Haiman, C. A., Sep 26 2014, In : Nature genetics. 46, 10, p. 1103-1109 7 p.

Research output: Contribution to journalArticle

Can urinary PCA3 Supplement PSA in the early detection of prostate cancer?

Wei, J. T., Feng, Z., Partin, A. W., Brown, E., Thompson, I., Sokoll, L., Chan, D. W., Lotan, Y., Kibel, A. S., Busby, J. E., Bidair, M., Lin, D. W., Taneja, S. S., Viterbo, R., Joon, A. Y., Dahlgren, J., Kagan, J., Srivastava, S. & Sanda, M. G., Dec 20 2014, In : Journal of Clinical Oncology. 32, 36, p. 4066-4072 7 p.

Research output: Contribution to journalArticle