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Author

  • Solomon H Snyder
Article

A Connective Tissue Mast-Cell-Specific Receptor Detects Bacterial Quorum-Sensing Molecules and Mediates Antibacterial Immunity

Pundir, P., Liu, R., Vasavda, C., Serhan, N., Limjunyawong, N., Yee, R., Zhan, Y., Dong, X., Wu, X., Zhang, Y., Snyder, S. H., Gaudenzio, N., Vidal, J. E. & Dong, X., Jul 10 2019, In : Cell Host and Microbe. 26, 1, p. 114-122.e8

Research output: Contribution to journalArticle

Amino acid signaling to mTOR mediated by inositol polyphosphate multikinase

Kim, S., Kim, S. F., Maag, D., Maxwell, M. J., Resnick, A. C., Juluri, K. R., Chakraborty, A., Koldobskiy, M. A., Cha, S. H., Barrow, R., Snowman, A. M. & Snyder, S. H., Feb 2 2011, In : Cell Metabolism. 13, 2, p. 215-221 7 p.

Research output: Contribution to journalArticle

AMP-activated protein kinase is physiologically regulated by inositol polyphosphate multikinase

Bang, S., Kim, S., Dailey, M. J., Chen, Y., Moran, T. H., Snyder, S. H. & Kim, S. F., Jan 10 2012, In : Proceedings of the National Academy of Sciences of the United States of America. 109, 2, p. 616-620 5 p.

Research output: Contribution to journalArticle

AMPA receptor upregulation in the nucleus accumbens shell of cocaine-sensitized rats depends upon S-nitrosylation of stargazin

Selvakumar, B., Campbell, P. W., Milovanovic, M., Park, D. J., West, A. R., Snyder, S. H. & Wolf, M. E., Jan 1 2014, In : Neuropharmacology. 77, p. 28-38 11 p.

Research output: Contribution to journalArticle

Antidepressant action of ketamine via mTOR is mediated by inhibition of nitrergic Rheb degradation

Harraz, M. M., Tyagi, R., Cortés, P. & Snyder, S. H., Mar 1 2016, In : Molecular psychiatry. 21, 3, p. 313-319 7 p.

Research output: Contribution to journalArticle

Behavioral effects of cocaine mediated by nitric oxide-GAPDH transcriptional signaling

Xu, R., Serritella, A. V., Sen, T., Farook, J. M., Sedlak, T. W., Baraban, J., Snyder, S. H. & Sen, N., May 22 2013, In : Neuron. 78, 4, p. 623-630 8 p.

Research output: Contribution to journalArticle

Bilirubin Links Heme Metabolism to Neuroprotection by Scavenging Superoxide

Vasavda, C., Kothari, R., Malla, A. P., Tokhunts, R., Lin, A., Ji, M., Ricco, C., Xu, R., Saavedra, H. G., Sbodio, J., Snowman, A. M., Albacarys, L., Hester, L., Sedlak, T. W., Paul, B. D. & Snyder, S. H., Oct 17 2019, In : Cell Chemical Biology. 26, 10, p. 1450-1460.e7

Research output: Contribution to journalArticle

Bryostatin-1 alleviates experimental multiple sclerosis

Kornberg, M., Smith, M. D., Shirazi, H. A., Calabresi, P., Snyder, S. H. & Kim, P., Feb 27 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 9, p. 2186-2191 6 p.

Research output: Contribution to journalArticle

Casein kinase-2 mediates cell survival through phosphorylation and degradation of inositol hexakisphosphate kinase-2

Chakraborty, A., Werner, J. K., Koldobskiy, M. A., Mustafa, A. K., Juluri, K. R., Pietropaoli, J., Snowman, A. M. & Snyder, S. H., Feb 8 2011, In : Proceedings of the National Academy of Sciences of the United States of America. 108, 6, p. 2205-2209 5 p.

Research output: Contribution to journalArticle

Collybolide is a novel biased agonist of ê-opioid receptors with potent antipruritic activity

Gupta, A., Gomes, I., Bobeck, E. N., Fakira, A. K., Massaro, N. P., Sharma, I., Cavé, A., Hamm, H. E., Parello, J., Devi, L. A. & Snyder, S. H., May 24 2016, In : Proceedings of the National Academy of Sciences of the United States of America. 113, 21, p. 6041-6046 6 p.

Research output: Contribution to journalArticle

Complementary roles of gasotransmitters CO and H2S in sleep apnea

Peng, Y. J., Zhang, X., Gridina, A., Chupikova, I., Mccormick, D. L., Thomas, R. J., Scammell, T. E., Kim, G., Vasavda, C., Nanduri, J., Kumar, G. K., Semenza, G. L., Snyder, S. H. & Prabhakar, N. R., Feb 7 2017, In : Proceedings of the National Academy of Sciences of the United States of America. 114, 6, p. 1413-1418 6 p.

Research output: Contribution to journalArticle

Constituents of bile, bilirubin and TUDCA, protect against oxidative stress-induced retinal degeneration

Oveson, B. C., Iwase, T., Hackett, S. F., Lee, S. Y., Usui, S., Sedlak, T. W., Snyder, S. H., Campochiaro, P. A. & Sung, J. U., Jan 1 2011, In : Journal of Neurochemistry. 116, 1, p. 144-153 10 p.

Research output: Contribution to journalArticle

Cyclic AMP-dependent phosphorylation of neuronal nitric oxide synthase mediates penile erection

Hurt, K. J., Sezen, S. F., Lagoda, G. F., Musicki, B., Rameau, G. A., Snyder, S. H. & Burnett, A. L., Oct 9 2012, In : Proceedings of the National Academy of Sciences of the United States of America. 109, 41, p. 16624-16629 6 p.

Research output: Contribution to journalArticle

Cystathionine γ-lyase deficiency mediates neurodegeneration in Huntington's disease

Paul, B. D., Sbodio, J. I., Xu, R., Vandiver, M. S., Cha, J. Y., Snowman, A. M. & Snyder, S. H., Jan 1 2014, In : Nature. 508, 7498, p. 96-100 5 p.

Research output: Contribution to journalArticle

Cysteine Metabolism in Neuronal Redox Homeostasis

Paul, B., Sbodio, J. & Snyder, S. H., Jan 1 2018, (Accepted/In press) In : Trends in Pharmacological Sciences.

Research output: Contribution to journalArticle

Developmental alcohol exposure impairs activity-dependent S-nitrosylation of NDEL1 for neuronal maturation

Saito, A., Taniguchi, Y., Kim, S. H., Selvakumar, B., Perez, G., Ballinger, M. D., Zhu, X., Sabra, J., Jallow, M., Yan, P., Ito, K., Rajendran, S., Hirotsune, S., Wynshaw-Boris, A., Snyder, S. H., Sawa, A. & Kamiya, A., Aug 1 2017, In : Cerebral Cortex. 27, 8, p. 3918-3929 12 p.

Research output: Contribution to journalArticle

Dexras1, a small GTPase, is required for glutamate-NMDA neurotoxicity

Chen, Y., Khan, R. S., Cwanger, A., Song, Y., Steenstra, C., Bang, S., Cheah, J. H., Dunaief, J., Shindler, K. S., Snyder, S. H. & Kim, S. F., Feb 20 2013, In : Journal of Neuroscience. 33, 8, p. 3582-3587 6 p.

Research output: Contribution to journalArticle

Dexras1 mediates glucocorticoid-associated adipogenesis and diet-induced obesity

Cha, J. Y., Kim, H. J., Yu, J. H., Xu, J., Kim, D., Paul, B. D., Choi, H., Kim, S., Lee, Y. J., Ho, G. P., Rao, F., Snyder, S. H. & Kim, J. W., Dec 17 2013, In : Proceedings of the National Academy of Sciences of the United States of America. 110, 51, p. 20575-20580 6 p.

Research output: Contribution to journalArticle

Dimethyl fumarate targets GAPDH and aerobic glycolysis to modulate immunity

Kornberg, M., Bhargava, P., Kim, P., Putluri, V., Snowman, A. M., Putluri, N., Calabresi, P. & Snyder, S. H., Mar 29 2018, (Accepted/In press) In : Science. p. 1-9 9 p.

Research output: Contribution to journalArticle

DISC1 in Astrocytes Influences Adult Neurogenesis and Hippocampus-Dependent Behaviors in Mice

Terrillion, C., Abazyan, B., Yang, Z., Crawford, J., Shevelkin, A., Jouroukhin, Y., Yoo, K. H., Cho, C. H., Roychaudhuri, R., Snyder, S. H., Jang, M. H. & Pletnikov, M., Oct 1 2017, In : Neuropsychopharmacology. 42, 11, p. 2242-2251 10 p.

Research output: Contribution to journalArticle

Disease onset in X-linked dystonia-parkinsonism correlates with expansion of a hexameric repeat within an SVA retrotransposon in TAF1

Bragg, D. C., Mangkalaphiban, K., Vaine, C. A., Kulkarni, N. J., Shin, D., Yadav, R., Dhakal, J., Ton, M. L., Cheng, A., Russo, C. T., Ang, M., Acuña, P., Go, C., Franceour, T. N., Multhaupt-Buell, T., Ito, N., Müller, U., Hendriks, W. T., Breakefield, X. O., Sharma, N. & 2 others, Ozelius, L. J. & Snyder, S. H., Dec 19 2017, In : Proceedings of the National Academy of Sciences of the United States of America. 114, 51, p. E11020-E11028

Research output: Contribution to journalArticle

Distinct cortical and striatal actions of a β-arrestin-biased dopamine D2 receptor ligand reveal unique antipsychotic-like properties

Urs, N. M., Gee, S. M., Pack, T. F., McCorvy, J. D., Evron, T., Snyder, J. C., Yang, X., Rodriguiz, R. M., Borrelli, E., Wetsel, W. C., Jin, J., Roth, B. L., O'Donnell, P., Caron, M. G. & Snyder, S. H., Dec 13 2016, In : Proceedings of the National Academy of Sciences of the United States of America. 113, 50, p. E8178-E8186

Research output: Contribution to journalArticle

D-serine in glia and neurons derives from 3-phosphoglycerate dehydrogenase

Ehmsen, J. T., Ma, T. M., Sason, H., Rosenberg, D., Ogo, T., Furuya, S., Snyder, S. H. & Wolosker, H., Jul 30 2013, In : Journal of Neuroscience. 33, 30, p. 12464-12469 6 p.

Research output: Contribution to journalArticle

Endogenous H2S is required for hypoxic sensing by carotid body glomus cells

Makarenko, V. V., Nanduri, J., Raghuraman, G., Fox, A. P., Gadalla, M. M., Kumar, G. K., Snyder, S. H. & Prabhakar, N. R., Nov 1 2012, In : American Journal of Physiology - Cell Physiology. 303, 9, p. C916-C923

Research output: Contribution to journalArticle

Glutathione is a physiologic reservoir of neuronal glutamate

Koga, M., Serritella, A. V., Messmer, M. M., Hayashi-Takagi, A., Hester, L. D., Snyder, S. H., Sawa, A. & Sedlak, T. W., Jun 17 2011, In : Biochemical and Biophysical Research Communications. 409, 4, p. 596-602 7 p.

Research output: Contribution to journalArticle

Golgi protein ACBD3 mediates neurotoxicity associated with huntington's disease

Sbodio, J. I., Paul, B. D., Machamer, C. E. & Snyder, S. H., May 12 2013, In : Cell Reports. 4, 5, p. 890-897 8 p.

Research output: Contribution to journalArticle

H2S production by reactive oxygen species in the carotid body triggers hypertension in a rodent model of sleep apnea

Yuan, G., Peng, Y. J., Khan, S. A., Nanduri, J., Singh, A., Vasavda, C., Semenza, G. L., Kumar, G. K., Snyder, S. H. & Prabhakar, N. R., Aug 16 2016, In : Science Signaling. 9, 441, ra80.

Research output: Contribution to journalArticle

Histone H2AX deficiency causes neurobehavioral deficits and impaired redox homeostasis

Weyemi, U., Paul, B. D., Snowman, A. M., Jailwala, P., Nussenzweig, A., Bonner, W. M. & Snyder, S. H., Dec 1 2018, In : Nature communications. 9, 1, 1526.

Research output: Contribution to journalArticle

Histone H2AX promotes neuronal health by controlling mitochondrial homeostasis

Weyemi, S., Paul, B., Bhattacharya, D., Malla, A. P., Boufraqech, M., Harraz, M., Bonner, W. M. & Snyder, S. H., Apr 9 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 15, p. 7471-7476 6 p.

Research output: Contribution to journalArticle

Human GAPDH is a target of aspirin's primary metabolite salicylic acid and its derivatives

Choi, H. W., Tian, M., Manohar, M., Harraz, M. M., Park, S. W., Schroeder, F. C., Snyder, S. H. & Klessig, D. F., Nov 2015, In : PloS one. 10, 11, e0143447.

Research output: Contribution to journalArticle

Human Genome-Wide RNAi Screen Identifies an Essential Role for Inositol Pyrophosphates in Type-I Interferon Response

Pulloor, N. K., Nair, S., Kostic, A. D., Bist, P., Weaver, J. D., Riley, A. M., Tyagi, R., Uchil, P. D., York, J. D., Snyder, S. H., García-Sastre, A., Potter, B. V. L., Lin, R., Shears, S. B., Xavier, R. J. & Krishnan, M. N., Feb 2014, In : PLoS pathogens. 10, 2, e1003981.

Research output: Contribution to journalArticle

Huntington's disease: Neural dysfunction linked to inositol polyphosphate multikinase

Ahmed, I., Sbodio, J. I., Harraz, M. M., Tyagi, R., Grima, J. C., Albacarys, L. K., Hubbi, M. E., Xu, R., Kim, S., Paul, B. D. & Snyder, S. H., Aug 4 2015, In : Proceedings of the National Academy of Sciences of the United States of America. 112, 31, p. 9751-9756 6 p.

Research output: Contribution to journalArticle

Hydrogen sulfide as endothelium-derived hyperpolarizing factor sulfhydrates potassium channels

Mustafa, A. K., Sikka, G., Gazi, S. K., Steppan, J., Jung, S. M., Bhunia, A. K., Barodka, V. M., Gazi, F. K., Barrow, R. K., Wang, R., Amzel, L. M., Berkowitz, D. E. & Snyder, S. H., Nov 11 2011, In : Circulation research. 109, 11, p. 1259-1268 10 p.

Research output: Contribution to journalArticle

Hydrogen sulfide-linked sulfhydration of NF-κB mediates its antiapoptotic actions

Sen, N., Paul, B. D., Gadalla, M. M., Mustafa, A. K., Sen, T., Xu, R., Kim, S. & Snyder, S. H., Jan 13 2012, In : Molecular cell. 45, 1, p. 13-24 12 p.

Research output: Contribution to journalArticle

Hypoxic regulation of the cerebral microcirculation is mediated by a carbon monoxide-sensitive hydrogen sulfide pathway

Morikawa, T., Kajimura, M., Nakamura, T., Hishiki, T., Nakanishi, T., Yukutake, Y., Nagahata, Y., Ishikawa, M., Hattori, K., Takenouchi, T., Takahashi, T., Ishii, I., Matsubara, K., Kabe, Y., Uchiyama, S., Nagata, E., Gadalla, M. M., Snyder, S. H. & Suematsu, M., Jan 24 2012, In : Proceedings of the National Academy of Sciences of the United States of America. 109, 4, p. 1293-1298 6 p.

Research output: Contribution to journalArticle

Identification of a bilirubin receptor that may mediate a component of cholestatic itch

Meixiong, J., Vasavda, C., Green, D., Zheng, Q., Qi, L., Kwatra, S. G., Hamilton, J. P., Snyder, S. H. & Dong, X., Jan 21 2019, In : eLife. 8, e44116.

Research output: Contribution to journalArticle

Open Access

Identity of the NMDA receptor coagonist is synapse specific and developmentally regulated in the hippocampus

Le Bail, M., Martineau, M., Sacchi, S., Yatsenko, N., Radzishevsky, I., Conrod, S., Ouares, K. A., Wolosker, H., Pollegioni, L., Billard, J. M., Mothet, J. P. & Snyder, S. H., Jan 13 2015, In : Proceedings of the National Academy of Sciences of the United States of America. 112, 2, p. E204-E213

Research output: Contribution to journalArticle

Inherent variations in co-h2s-mediated carotid body O 2 sensing mediate hypertension and pulmonary edema

Peng, Y. J., Makarenko, V. V., Nanduri, J., Vasavda, C., Raghuraman, G., Yuan, G., Gadalla, M. M., Kumar, G. K., Snyder, S. H. & Prabhakar, N. R., Jan 21 2014, In : Proceedings of the National Academy of Sciences of the United States of America. 111, 3, p. 1174-1179 6 p.

Research output: Contribution to journalArticle

Open Access

Inhibition of IP6K1 suppresses neutrophil-mediated pulmonary damage in bacterial pneumonia

Hou, Q., Liu, F., Chakraborty, A., Jia, Y., Prasad, A., Yu, H., Zhao, L., Ye, K., Snyder, S. H., Xu, Y. & Luo, H. R., Apr 4 2018, In : Science translational medicine. 10, 435, eaal4045.

Research output: Contribution to journalArticle

Inositol hexakisphosphate (IP6) generated by IP5K mediates cullin-COP9 signalosome interactions and CRL function

Scherer, P. C., Ding, Y., Liu, Z., Xu, J., Mao, H., Barrow, J. C., Wei, N., Zheng, N., Snyder, S. H. & Rao, F., Mar 29 2016, In : Proceedings of the National Academy of Sciences of the United States of America. 113, 13, p. 3503-3508 6 p.

Research output: Contribution to journalArticle

Inositol hexakisphosphate kinase-1 mediates assembly/disassembly of the crl4-signalosome complex to regulate DNA repair and cell death

Rao, F., Xu, J., Khan, A. B., Gadalla, M. M., Cha, J. Y., Xu, R., Tyagi, R., Dang, Y., Chakraborty, A. & Snyder, S. H., Nov 11 2014, In : Proceedings of the National Academy of Sciences of the United States of America. 111, 45, p. 16005-16010 6 p.

Research output: Contribution to journalArticle

Inositol hexakisphosphate kinase-1 regulates behavioral responses via GSK3 signaling pathways

Chakraborty, A., Latapy, C., Xu, J., Snyder, S. H. & Beaulieu, J. M., Mar 1 2014, In : Molecular psychiatry. 19, 3, p. 284-293 10 p.

Research output: Contribution to journalArticle

Inositol hexakisphosphate kinase 1 regulates neutrophil function in innate immunity by inhibiting phosphatidylinositol-(3,4,5)-trisphosphate signaling

Prasad, A., Jia, Y., Chakraborty, A., Li, Y., Jain, S. K., Zhong, J., Roy, S. G., Loison, F., Mondal, S., Sakai, J., Blanchard, C., Snyder, S. H. & Luo, H. R., Aug 1 2011, In : Nature Immunology. 12, 8, p. 752-760 9 p.

Research output: Contribution to journalArticle

Inositol hexakisphosphate kinase-2 in cerebellar granule cells regulates Purkinje cells and motor coordination via protein 4.1N

Nagpal, L., Fu, C. & Snyder, S. H., Aug 22 2018, In : Journal of Neuroscience. 38, 34, p. 7409-7419 11 p.

Research output: Contribution to journalArticle

Inositol hexakisphosphate kinase 3 promotes focal adhesion turnover via interactions with dynein intermediate chain 2

Rojas, T., Cheng, W., Gao, Z., Liu, X., Wang, Y., Malla, A. P., Chin, A. C., Romer, L. H., Snyder, S. H. & Fu, C., Feb 19 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 8, p. 3278-3287 10 p.

Research output: Contribution to journalArticle

Inositol hexakisphosphate kinase-3 regulates the morphology and synapse formation of cerebellar purkinje cells via spectrin/adducin

Fu, C., Xu, J., Li, R. J., Crawford, X. A., Khan, A. B., Ma, T. M., Cha, J. Y., Snowman, A. M., Pletnikov, M. V. & Snyder, S. H., Aug 5 2015, In : Journal of Neuroscience. 35, 31, p. 11056-11067 12 p.

Research output: Contribution to journalArticle

Inositol polyphosphate multikinase inhibits angiogenesis via inositol pentakisphosphate-induced HIF-1α degradation

Fu, C., Tyagi, R., Chin, A. C., Rojas, T., Li, R. J., Guha, P., Bernstein, I. A., Rao, F., Xu, R., Cha, J., Xu, J., Snowman, A. M., Semenza, G. L. & Snyder, S. H., Feb 2 2018, In : Circulation Research. 122, 3, p. 457-472 16 p.

Research output: Contribution to journalArticle

Inositol polyphosphate multikinase is a coactivator for serum response factor-dependent induction of immediate early genes

Kim, E., Tyagi, R., Lee, J. Y., Park, J., Kim, Y. R., Beon, J., Chen, P. Y., Cha, J. Y., Snyder, S. H. & Kim, S., Dec 3 2013, In : Proceedings of the National Academy of Sciences of the United States of America. 110, 49, p. 19938-19943 6 p.

Research output: Contribution to journalArticle