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Author

  • Solomon H Snyder
2019

A Connective Tissue Mast-Cell-Specific Receptor Detects Bacterial Quorum-Sensing Molecules and Mediates Antibacterial Immunity

Pundir, P., Liu, R., Vasavda, C., Serhan, N., Limjunyawong, N., Yee, R., Zhan, Y., Dong, X., Wu, X., Zhang, Y., Snyder, S. H., Gaudenzio, N., Vidal, J. E. & Dong, X., Jul 10 2019, In : Cell Host and Microbe. 26, 1, p. 114-122.e8

Research output: Contribution to journalArticle

Bilirubin Links Heme Metabolism to Neuroprotection by Scavenging Superoxide

Vasavda, C., Kothari, R., Malla, A. P., Tokhunts, R., Lin, A., Ji, M., Ricco, C., Xu, R., Saavedra, H. G., Sbodio, J., Snowman, A. M., Albacarys, L., Hester, L., Sedlak, T. W., Paul, B. D. & Snyder, S. H., Oct 17 2019, In : Cell Chemical Biology. 26, 10, p. 1450-1460.e7

Research output: Contribution to journalArticle

Histone H2AX promotes neuronal health by controlling mitochondrial homeostasis

Weyemi, S., Paul, B., Bhattacharya, D., Malla, A. P., Boufraqech, M., Harraz, M., Bonner, W. M. & Snyder, S. H., Apr 9 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 15, p. 7471-7476 6 p.

Research output: Contribution to journalArticle

Identification of a bilirubin receptor that may mediate a component of cholestatic itch

Meixiong, J., Vasavda, C., Green, D., Zheng, Q., Qi, L., Kwatra, S. G., Hamilton, J. P., Snyder, S. H. & Dong, X., Jan 21 2019, In : eLife. 8, e44116.

Research output: Contribution to journalArticle

Open Access
Open Access

Inositol hexakisphosphate kinase 3 promotes focal adhesion turnover via interactions with dynein intermediate chain 2

Rojas, T., Cheng, W., Gao, Z., Liu, X., Wang, Y., Malla, A. P., Chin, A. C., Romer, L. H., Snyder, S. H. & Fu, C., Feb 19 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 8, p. 3278-3287 10 p.

Research output: Contribution to journalArticle

Inositol polyphosphate multikinase mediates extinction of fear memory

Park, J., Longo, F., Park, S. J., Lee, S., Bae, M., Tyagi, R., Han, J. H., Kim, S., Santini, E., Klann, E. & Snyder, S. H., Feb 12 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 7, p. 2707-2712 6 p.

Research output: Contribution to journalArticle

IPMK Mediates Activation of ULK Signaling and Transcriptional Regulation of Autophagy Linked to Liver Inflammation and Regeneration

Guha, P., Tyagi, R., Chowdhury, S., Reilly, L., Fu, C., Xu, R., Resnick, A. C. & Snyder, S. H., Mar 5 2019, In : Cell Reports. 26, 10, p. 2692-2703.e7

Research output: Contribution to journalArticle

Open Access

Redox Mechanisms in Neurodegeneration: From Disease Outcomes to Therapeutic Opportunities

Sbodio, J. I., Snyder, S. H. & Paul, B. D., 2019, In : Antioxidants and Redox Signaling. 30, 11, p. 1450-1499 50 p.

Research output: Contribution to journalReview article

Selective Persulfide Detection Reveals Evolutionarily Conserved Antiaging Effects of S-Sulfhydration

Zivanovic, J., Kouroussis, E., Kohl, J. B., Adhikari, B., Bursac, B., Schott-Roux, S., Petrovic, D., Miljkovic, J. L., Thomas-Lopez, D., Jung, Y., Miler, M., Mitchell, S., Milosevic, V., Gomes, J. E., Benhar, M., Gonzales-Zorn, B., Ivanovic-Burmazovic, I., Torregrossa, R., Mitchell, J. R., Whiteman, M. & 5 others, Schwarz, G., Snyder, S. H., Paul, B. D., Carroll, K. S. & Filipovic, M. R., Dec 3 2019, In : Cell Metabolism. 30, 6, p. 1152-1170.e13

Research output: Contribution to journalArticle

Open Access
2018

Bryostatin-1 alleviates experimental multiple sclerosis

Kornberg, M., Smith, M. D., Shirazi, H. A., Calabresi, P., Snyder, S. H. & Kim, P., Feb 27 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 9, p. 2186-2191 6 p.

Research output: Contribution to journalArticle

Chapter 2: Production of NO - The l-arginine/NOS/NO System

Paul, B. & Snyder, S. H., Jan 1 2018, RSC Metallobiology. 12 ed. Royal Society of Chemistry, p. 29-43 15 p. (RSC Metallobiology; vol. 2018-January, no. 12).

Research output: Chapter in Book/Report/Conference proceedingChapter

Cysteine Metabolism in Neuronal Redox Homeostasis

Paul, B., Sbodio, J. & Snyder, S. H., Jan 1 2018, (Accepted/In press) In : Trends in Pharmacological Sciences.

Research output: Contribution to journalArticle

Dimethyl fumarate targets GAPDH and aerobic glycolysis to modulate immunity

Kornberg, M., Bhargava, P., Kim, P., Putluri, V., Snowman, A. M., Putluri, N., Calabresi, P. & Snyder, S. H., Mar 29 2018, (Accepted/In press) In : Science. p. 1-9 9 p.

Research output: Contribution to journalArticle

Gasotransmitter hydrogen sulfide signaling in neuronal health and disease

Paul, B. & Snyder, S. H., Mar 1 2018, In : Biochemical Pharmacology. 149, p. 101-109 9 p.

Research output: Contribution to journalReview article

Histone H2AX deficiency causes neurobehavioral deficits and impaired redox homeostasis

Weyemi, U., Paul, B. D., Snowman, A. M., Jailwala, P., Nussenzweig, A., Bonner, W. M. & Snyder, S. H., Dec 1 2018, In : Nature communications. 9, 1, 1526.

Research output: Contribution to journalArticle

Inhibition of IP6K1 suppresses neutrophil-mediated pulmonary damage in bacterial pneumonia

Hou, Q., Liu, F., Chakraborty, A., Jia, Y., Prasad, A., Yu, H., Zhao, L., Ye, K., Snyder, S. H., Xu, Y. & Luo, H. R., Apr 4 2018, In : Science translational medicine. 10, 435, eaal4045.

Research output: Contribution to journalArticle

Inositol hexakisphosphate kinase-2 in cerebellar granule cells regulates Purkinje cells and motor coordination via protein 4.1N

Nagpal, L., Fu, C. & Snyder, S. H., Aug 22 2018, In : Journal of Neuroscience. 38, 34, p. 7409-7419 11 p.

Research output: Contribution to journalArticle

Inositol polyphosphate multikinase inhibits angiogenesis via inositol pentakisphosphate-induced HIF-1α degradation

Fu, C., Tyagi, R., Chin, A. C., Rojas, T., Li, R. J., Guha, P., Bernstein, I. A., Rao, F., Xu, R., Cha, J., Xu, J., Snowman, A. M., Semenza, G. L. & Snyder, S. H., Feb 2 2018, In : Circulation Research. 122, 3, p. 457-472 16 p.

Research output: Contribution to journalArticle

Multiple aspects of male germ cell development and interactions with Sertoli cells require inositol hexakisphosphate kinase-1

Fu, C., Rojas, T., Chin, A. C., Cheng, W., Bernstein, I. A., Albacarys, L. K., Wright, W. W. & Snyder, S. H., Dec 1 2018, In : Scientific Reports. 8, 1, 7039.

Research output: Contribution to journalArticle

Opportunities for the repurposing of PARP inhibitors for the therapy of non-oncological diseases

Berger, N. A., Besson, V. C., Boulares, A. H., Bürkle, A., Chiarugi, A., Clark, R. S., Curtin, N. J., Cuzzocrea, S., Dawson, T. M., Dawson, V. L., Haskó, G., Liaudet, L., Moroni, F., Pacher, P., Radermacher, P., Salzman, A. L., Snyder, S. H., Soriano, F. G., Strosznajder, R. P., Sümegi, B. & 2 others, Swanson, R. A. & Szabo, C., 2018, In : British Journal of Pharmacology. 175, 2, p. 192-222 31 p.

Research output: Contribution to journalReview article

Regulators of the transsulfuration pathway

Sbodio, J., Snyder, S. H. & Paul, B., Jan 1 2018, (Accepted/In press) In : British Journal of Pharmacology.

Research output: Contribution to journalArticle

The brain harbors many neurotransmitters

Snyder, S. H., Apr 24 2018, Think Tank: Forty Neuroscientists Explore the Biological Roots of Human Experience. Yale University Press, p. 88-94 7 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2017

A Life of Neurotransmitters

Snyder, S. H., Jan 6 2017, In : Annual Review of Pharmacology and Toxicology. 57, p. 1-11 11 p.

Research output: Contribution to journalReview article

Antidepressant Actions of Ketamine Mediated by the Mechanistic Target of Rapamycin, Nitric Oxide, and Rheb

Harraz, M. & Snyder, S. H., Jul 1 2017, In : Neurotherapeutics. 14, 3, p. 728-733 6 p.

Research output: Contribution to journalReview article

Complementary roles of gasotransmitters CO and H2S in sleep apnea

Peng, Y. J., Zhang, X., Gridina, A., Chupikova, I., Mccormick, D. L., Thomas, R. J., Scammell, T. E., Kim, G., Vasavda, C., Nanduri, J., Kumar, G. K., Semenza, G. L., Snyder, S. H. & Prabhakar, N. R., Feb 7 2017, In : Proceedings of the National Academy of Sciences of the United States of America. 114, 6, p. 1413-1418 6 p.

Research output: Contribution to journalArticle

Developmental alcohol exposure impairs activity-dependent S-nitrosylation of NDEL1 for neuronal maturation

Saito, A., Taniguchi, Y., Kim, S. H., Selvakumar, B., Perez, G., Ballinger, M. D., Zhu, X., Sabra, J., Jallow, M., Yan, P., Ito, K., Rajendran, S., Hirotsune, S., Wynshaw-Boris, A., Snyder, S. H., Sawa, A. & Kamiya, A., Aug 1 2017, In : Cerebral Cortex. 27, 8, p. 3918-3929 12 p.

Research output: Contribution to journalArticle

DISC1 in Astrocytes Influences Adult Neurogenesis and Hippocampus-Dependent Behaviors in Mice

Terrillion, C., Abazyan, B., Yang, Z., Crawford, J., Shevelkin, A., Jouroukhin, Y., Yoo, K. H., Cho, C. H., Roychaudhuri, R., Snyder, S. H., Jang, M. H. & Pletnikov, M., Oct 1 2017, In : Neuropsychopharmacology. 42, 11, p. 2242-2251 10 p.

Research output: Contribution to journalArticle

Disease onset in X-linked dystonia-parkinsonism correlates with expansion of a hexameric repeat within an SVA retrotransposon in TAF1

Bragg, D. C., Mangkalaphiban, K., Vaine, C. A., Kulkarni, N. J., Shin, D., Yadav, R., Dhakal, J., Ton, M. L., Cheng, A., Russo, C. T., Ang, M., Acuña, P., Go, C., Franceour, T. N., Multhaupt-Buell, T., Ito, N., Müller, U., Hendriks, W. T., Breakefield, X. O., Sharma, N. & 2 others, Ozelius, L. J. & Snyder, S. H., Dec 19 2017, In : Proceedings of the National Academy of Sciences of the United States of America. 114, 51, p. E11020-E11028

Research output: Contribution to journalArticle

Measuring g-protein-coupled receptor signaling via radio-labeled GTP binding

Vasavda, C., Zaccor, N. W., Scherer, P. C., Sumner, C. & Snyder, S. H., Jun 9 2017, In : Journal of Visualized Experiments. 2017, 124, e55561.

Research output: Contribution to journalArticle

Mutant Huntingtin Disrupts the Nuclear Pore Complex

Grima, J. C., Daigle, J. G., Arbez, N., Cunningham, K. C., Zhang, K., Ochaba, J., Geater, C., Morozko, E., Stocksdale, J., Glatzer, J. C., Pham, J. T., Ahmed, I., Peng, Q., Wadhwa, H., Pletnikova, O., Troncoso, J. C., Duan, W., Snyder, S. H., Ranum, L. P. W., Thompson, L. M. & 3 others, Lloyd, T., Ross, C. A. & Rothstein, J. D., Apr 5 2017, In : Neuron. 94, 1, p. 93-107.e6

Research output: Contribution to journalArticle

Neuronal migration is mediated by inositol hexakisphosphate kinase 1 via α-actinin and focal adhesion kinase

Fu, C., Xu, J., Cheng, W., Rojas, T., Chin, A. C., Snowman, A. M., Harraz, M. & Snyder, S. H., Feb 21 2017, In : Proceedings of the National Academy of Sciences of the United States of America. 114, 8, p. 2036-2041 6 p.

Research output: Contribution to journalArticle

TRPV1 is a physiological regulator of μ-opioid receptors

Scherer, P. C., Zaccor, N. W., Neumann, N. M., Vasavda, C., Barrow, R., Ewald, A. J., Rao, F., Sumner, C. J. & Snyder, S. H., Dec 19 2017, In : Proceedings of the National Academy of Sciences of the United States of America. 114, 51, p. 13561-13566 6 p.

Research output: Contribution to journalArticle

2016

Antidepressant action of ketamine via mTOR is mediated by inhibition of nitrergic Rheb degradation

Harraz, M. M., Tyagi, R., Cortés, P. & Snyder, S. H., Mar 1 2016, In : Molecular psychiatry. 21, 3, p. 313-319 7 p.

Research output: Contribution to journalArticle

Collybolide is a novel biased agonist of ê-opioid receptors with potent antipruritic activity

Gupta, A., Gomes, I., Bobeck, E. N., Fakira, A. K., Massaro, N. P., Sharma, I., Cavé, A., Hamm, H. E., Parello, J., Devi, L. A. & Snyder, S. H., May 24 2016, In : Proceedings of the National Academy of Sciences of the United States of America. 113, 21, p. 6041-6046 6 p.

Research output: Contribution to journalArticle

Differential binding properties of some opiates and opioid peptides

Creese, I., Childers, S. R., Simantov, R. & Snyder, S. H., Jan 14 2016, Endorphins in Mental Health Research. Palgrave Macmillan, p. 366-374 9 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Distinct cortical and striatal actions of a β-arrestin-biased dopamine D2 receptor ligand reveal unique antipsychotic-like properties

Urs, N. M., Gee, S. M., Pack, T. F., McCorvy, J. D., Evron, T., Snyder, J. C., Yang, X., Rodriguiz, R. M., Borrelli, E., Wetsel, W. C., Jin, J., Roth, B. L., O'Donnell, P., Caron, M. G. & Snyder, S. H., Dec 13 2016, In : Proceedings of the National Academy of Sciences of the United States of America. 113, 50, p. E8178-E8186

Research output: Contribution to journalArticle

Enkephalin levels in mouse brain: Diurnal variation, post-mortem degradation, and effect of cycloheximide

Childers, S. R. & Snyder, S. H., Jan 14 2016, Endorphins in Mental Health Research. Palgrave Macmillan, p. 181-188 8 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Foreword

Snyder, S. H., 2016, In : Advances in Pharmacology. 76, p. 13-15 3 p.

Research output: Contribution to journalEditorial

H2S production by reactive oxygen species in the carotid body triggers hypertension in a rodent model of sleep apnea

Yuan, G., Peng, Y. J., Khan, S. A., Nanduri, J., Singh, A., Vasavda, C., Semenza, G. L., Kumar, G. K., Snyder, S. H. & Prabhakar, N. R., Aug 16 2016, In : Science Signaling. 9, 441, ra80.

Research output: Contribution to journalArticle

Histochemical localization of the enkephalins

Uhl, G., Kuhar, M. J., Goodman, R. R. & Snyder, S. H., Jan 14 2016, Endorphins in Mental Health Research. Palgrave Macmillan, p. 74-83 10 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Inositol hexakisphosphate (IP6) generated by IP5K mediates cullin-COP9 signalosome interactions and CRL function

Scherer, P. C., Ding, Y., Liu, Z., Xu, J., Mao, H., Barrow, J. C., Wei, N., Zheng, N., Snyder, S. H. & Rao, F., Mar 29 2016, In : Proceedings of the National Academy of Sciences of the United States of America. 113, 13, p. 3503-3508 6 p.

Research output: Contribution to journalArticle

2015

H2S: A Novel Gasotransmitter that Signals by Sulfhydration

Paul, B. D. & Snyder, S. H., Jan 1 2015, In : Trends in biochemical sciences. 40, 11, p. 687-700 14 p.

Research output: Contribution to journalReview article