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2018

A call for more science in forensic science

Bell, S., Sah, S., Albright, T. D., James Gates, S., Bonner Denton, M. & Casadevall, A., May 1 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 18, p. 4541-4544 4 p.

Research output: Contribution to journalReview article

Forensic Sciences
Social Justice
Financial Support
Law Enforcement
DNA

Acknowledgment of invited editors

Casadevall, A. Mar 1 2018 In : mBio. 9, 2, e00731-18

Research output: Contribution to journalEditorial

Biological Warfare Agents
Benchmarking
Weapons
Influenza in Birds
Physics

Antibody-based vaccine strategies against intracellular pathogens

Casadevall, A. Aug 1 2018 In : Current Opinion in Immunology. 53, p. 74-80 7 p.

Research output: Contribution to journalReview article

Vaccines
Antibodies
Allergy and Immunology
Humoral Immunity
Cellular Immunity

A Therapeutic Vaccine for Recurrent Vulvovaginal Candidiasis

Casadevall, A. & Pirofski, L. A., Jun 1 2018, In : Clinical Infectious Diseases. 66, 12, p. 1937-1939 3 p.

Research output: Contribution to journalReview article

Vulvovaginal Candidiasis
Vaccines
Therapeutics

Automated measurement of cryptococcal species polysaccharide capsule and cell body

Dragotakes, Q. & Casadevall, A. Jan 11 2018 In : Journal of Visualized Experiments. 2018, 131, e56957

Research output: Contribution to journalArticle

Musical instruments
Cryptococcus
Polysaccharides
Capsules
Communicable Diseases

Cell-wall dyes interfere with cryptococcus neoformans melanin deposition

Perez-Dulzaides, R., Camacho, E., Cordero, R. J. B. & Casadevall, A., Aug 1 2018, In : Microbiology (United Kingdom). 164, 8, p. 1012-1022 11 p., 000682

Research output: Contribution to journalArticle

Cryptococcus neoformans
Melanins
Cell Wall
Coloring Agents
Chitin

Conservation of intracellular pathogenic strategy among distantly related cryptococcal species

Freij, J. B., Fu, M. S., De Leon Rodriguez, C. M., Dziedzic, A., Jedlicka, A. E., Dragotakes, Q., Rossi, D. C. P., Jung, E. H., Coelho, C. & Casadevall, A., Jul 1 2018, In : Infection and Immunity. 86, 7, e00946-17

Research output: Contribution to journalArticle

Cryptococcus gattii
Cryptococcus neoformans
Macrophages
Exocytosis
Cryptococcus

Cryptococcus neoformans urease affects the outcome of intracellular pathogenesis by modulating phagolysosomal pH

Fu, M. S., Coelho, C., De Leon-Rodriguez, C. M., Rossi, D. C. P., Camacho, E., Jung, E. H., Kulkarni, M. & Casadevall, A., Jun 1 2018, In : PLoS Pathogens. 14, 6, e1007144

Research output: Contribution to journalArticle

Cryptococcus neoformans
Urease
Macrophages
Exocytosis
Nitrogen

Divalent metal cations potentiate the predatory capacity of amoeba for Cryptococcus neoformans

Fu, M. S. & Casadevall, A. Feb 1 2018 In : Applied and Environmental Microbiology. 84, 3, e01717-17

Research output: Contribution to journalArticle

chemical environmental conditions
Antigen-antibody reactions
antigen-antibody reactions
Immunology
Antigen-Antibody Reactions

Elegant science

Casadevall, A. & Fang, F. C., Jan 1 2018, In : mBio. 9, 1, e00043-18

Research output: Contribution to journalEditorial

Beauty
Biological Science Disciplines

Mechanisms of Cryptococcus neoformans-mediated host damage

Casadevall, A., Coelho, C. & Alanio, A., Apr 30 2018, In : Frontiers in Immunology. 9, APR, 855

Research output: Contribution to journalReview article

Cryptococcus neoformans
Cryptococcosis
Exocytosis
Organelles
Homeostasis

Melanin triggers antifungal defences

Casadevall, A., Mar 15 2018, In : Nature. 555, 7696, p. 319-320 2 p.

Research output: Contribution to journalShort survey

melanin
defence

Structure-function analysis and therapeutic efficacy of antibodies to fungal melanin for melanoma radioimmunotherapy

Nosanchuk, J. D., Jeyakumar, A., Ray, A., Revskaya, E., Jiang, Z., Bryan, R. A., Allen, K. J. H., Jiao, R., Malo, M. E., Gómez, B. L., Morgenstern, A., Bruchertseifer, F., Rickles, D., Thornton, G. B., Bowen, A., Casadevall, A. & Dadachova, E., Dec 1 2018, In : Scientific Reports. 8, 1, 5466

Research output: Contribution to journalArticle

Fungal Antibodies
Radioimmunotherapy
Melanins
Melanoma
Immunoglobulin G

Testing Hypotheses on Risk Factors for Scientific Misconduct via Matched-Control Analysis of Papers Containing Problematic Image Duplications

Fanelli, D., Costas, R., Fang, F. C., Casadevall, A. & Bik, E. M., Feb 19 2018, (Accepted/In press) In : Science and Engineering Ethics. p. 1-19 19 p.

Research output: Contribution to journalArticle

Scientific Misconduct
hypothesis testing
Pressure
Testing
Research

The capsule of Cryptococcus neoformans

Casadevall, A., Coelho, C., Cordero, R. J. B., Dragotakes, Q., Jung, E., Vij, R. & Wear, M. P., Jan 1 2018, (Accepted/In press) In : Virulence.

Research output: Contribution to journalArticle

Cryptococcus neoformans
Capsules
Fungi
Physical Chemistry
Desiccation

The outcome of the cryptococcus neoformans–macrophage interaction depends on phagolysosomal membrane integrity

De Leon-Rodriguez, C. M., Rossi, D. C. P., Fu, M. S., Dragotakes, Q., Coelho, C., Ros, I. G., Caballero, B., Nolan, S. J. & Casadevall, A., Jul 15 2018, In : Journal of Immunology. 201, 2, p. 583-603 21 p.

Research output: Contribution to journalArticle

Cryptococcus neoformans
Macrophages
Membranes
Phospholipases
Exocytosis

The putative flippase Apt1 is required for intracellular membrane architecture and biosynthesis of polysaccharide and lipids in Cryptococcus neoformans

Rizzo, J., Colombo, A. C., Zamith-Miranda, D., Silva, V. K. A., Allegood, J. C., Casadevall, A., Del Poeta, M., Nosanchuk, J. D., Kronstad, J. W. & Rodrigues, M. L., Mar 1 2018, In : Biochimica et Biophysica Acta - Molecular Cell Research. 1865, 3, p. 532-541 10 p.

Research output: Contribution to journalArticle

Intracellular Membranes
Cryptococcus neoformans
Polysaccharides
Lipids
Glucosylceramides

The Silver Lining in Gain-of-Function Experiments with Pathogens of Pandemic Potential

Imperiale, M. J., Howard, D. & Casadevall, A., Jan 1 2018, Methods in Molecular Biology. Humana Press Inc., p. 575-587 13 p. (Methods in Molecular Biology; vol. 1836)

Research output: Chapter in Book/Report/Conference proceedingChapter

Influenza in Birds
Pandemics
Orthomyxoviridae
Uncertainty
Accidents

The viscoelastic properties of the fungal cell wall allow traffic of ambisome as intact liposome vesicles

Walker, L., Sood, P., Lenardon, M. D., Milne, G., Olson, J., Jensen, G., Wolf, J., Casadevall, A., Adler-Moore, J. & Gow, N. A. R., Jan 1 2018, In : mBio. 9, 1, e02383-17

Research output: Contribution to journalArticle

Amphotericin B
Liposomes
Cell Wall
Cell Membrane
Candida albicans

Titan cells formation in Cryptococcus neoformans is finely tuned by environmental conditions and modulated by positive and negative genetic regulators

Hommel, B., Mukaremera, L., Cordero, R. J. B., Coelho, C., Desjardins, C. A., Sturny-Leclère, A., Janbon, G., Perfect, J. R., Fraser, J. A., Casadevall, A., Cuomo, C. A., Dromer, F., Nielsen, K. & Alanio, A., May 1 2018, In : PLoS Pathogens. 14, 5, e1006982

Research output: Contribution to journalArticle

Saturn
Cryptococcus neoformans
Quorum Sensing
Cell Size
Cell Enlargement

Using preprints for journal clubs

Casadevall, A. & Gow, N., Mar 1 2018, In : mBio. 9, 2, e00516-18

Research output: Contribution to journalEditorial

Publications
Teaching
Literature
Art
Students

What is a host? Attributes of individual susceptibility

Casadevall, A. & Pirofski, L. A., Feb 1 2018, In : Infection and Immunity. 86, 2, e00636-17

Research output: Contribution to journalShort survey

Virulence
Causality
Germ Theory of Disease
History
Microbiota
2017

32-Phosphorus selectively delivered by listeria to pancreatic cancer demonstrates a strong therapeutic effect

Chandra, D., Selvanesan, B. C., Yuan, Z., Libutti, S. K., Koba, W., Beck, A., Zhu, K., Casadevall, A., Dadachova, E. & Gravekamp, C., 2017, In : Oncotarget. 8, 13, p. 20729-20740 12 p.

Research output: Contribution to journalArticle

Listeria
Therapeutic Uses
Pancreatic Neoplasms
Phosphorus
Neoplasms

A Monoclonal Antibody to Cryptococcus neoformans Glucuronoxylomannan Manifests Hydrolytic Activity for Both Peptides and Polysaccharides

Bowen, A., Wear, M. P., Cordero, R. J. B., Oscarson, S. & Casadevall, A., Jan 13 2017, In : Journal of Biological Chemistry. 292, 2, p. 417-434 18 p.

Research output: Contribution to journalArticle

Catalytic Antibodies
Cryptococcus neoformans
Monoclonal Antibodies
Antibodies
Polysaccharides

Antibodies to mycobacterium tuberculosis

Casadevall, A. Jan 19 2017 In : New England Journal of Medicine. 376, 3, p. 283-285 3 p.

Research output: Contribution to journalShort survey

Bacterial Antibodies
Fc Receptors
Humoral Immunity
Mycobacterium tuberculosis
B-Lymphocytes

Antibody-mediated catalysis in infection and immunity

Bowen, A., Wear, M. & Casadevall, A., Sep 1 2017, In : Infection and Immunity. 85, 9, e00202-17

Research output: Contribution to journalShort survey

Catalytic Antibodies
Catalysis
Immunity
Antibodies
Infection

Continental drift and speciation of the Cryptococcus neoformans and Cryptococcus gattii species complexes

Casadevall, A., Freij, J. B., Hann-Soden, C. & Taylor, J. Mar 1 2017 In : mSphere. 2, 2, e00103-17

Research output: Contribution to journalComment/debate

Cryptococcus gattii
Cryptococcus neoformans
South America
South Africa
Virulence Factors

Crisis in infectious diseases: 2 decades later

Casadevall, A., Apr 1 2017, In : Clinical Infectious Diseases. 64, 7, p. 823-828 6 p.

Research output: Contribution to journalArticle

Communicable Diseases

Don't Forget the Fungi When Considering Global Catastrophic Biorisks

Casadevall, A., Jul 1 2017, In : Health security. 15, 4, p. 341-342 2 p.

Research output: Contribution to journalShort survey

Fungi
fungus

Enhanced control of Mycobacterium tuberculosis extrapulmonary dissemination in mice by an arabinomannan-protein conjugate vaccine

Prados-Rosales, R. , Carreño, L. , Cheng, T. , Blanc, C. , Weinrick, B. , Malek, A. , Lowary, T. L. , Baena, A. , Joe, M. , Bai, Y. , Kalscheuer, R. , Batista-Gonzalez, A. , Saavedra, N. A. , Sampedro, L. , Tomás, J. , Anguita, J. , Hung, S. C. , Tripathi, A. , Xu, J. , Glatman-Freedman, A. & 5 others Jacobs, W. R., Chan, J., Porcelli, S. A., Achkar, J. M. & Casadevall, A., Mar 1 2017, In : PLoS Pathogens. 13, 3, e1006250

Research output: Contribution to journalArticle

Conjugate Vaccines
Mycobacterium tuberculosis
Antibody Formation
Polysaccharides
Tuberculosis

First draft genome sequence of the pathogenic fungus Lomentospora prolificans (formerly Scedosporium prolificans)

Luo, R., Zimin, A., Workman, R., Fan, Y., Pertea, G., Grossman, N., Wear, M. P., Jia, B., Miller, H., Casadevall, A., Timp, W., Zhang, S. X. & Salzberg, S. L., Nov 1 2017, In : G3: Genes, Genomes, Genetics. 7, 11, p. 3831-3836 6 p.

Research output: Contribution to journalArticle

Scedosporium
Nanopores
Chromosomes, Human, Pair 11
Fungi
Gels

Forensic science must be scientific

Sah, S., Casadevall, A., Bell, S., Gates, S. J., Albright, T. D. & Denton, M. B., Oct 1 2017, In : Scientific American. 317, 4, 1 p.

Research output: Contribution to journalComment/debate

Fungi that infect humans

Köhler, J. R., Hube, B., Puccia, R., Casadevall, A. & Perfect, J. R., Jun 1 2017, In : Microbiology spectrum. 5, 3, FUNK-0014-2016

Research output: Contribution to journalArticle

Fungi
fungus
pathogen
body temperature
commensalism

Galectin-3 impacts Cryptococcus neoformans infection through direct antifungal effects

Almeida, F., Wolf, J. M., Da Silva, T. A., Deleon-Rodriguez, C. M., Rezende, C. P., Pessoni, A. M., Fernandes, F. F., Silva-Rocha, R., Martinez, R., Rodrigues, M. L., Roque-Barreira, M. C. & Casadevall, A., Dec 1 2017, In : Nature Communications. 8, 1, 1968

Research output: Contribution to journalArticle

cells and cell components
fungal diseases
disease treatment
fungal disease
Galectin 3

Graduate biomedical science education needs a new philosophy

Bosch, G. & Casadevall, A. Nov 1 2017 In : mBio. 8, 6, e01539-17

Research output: Contribution to journalArticle

Graduate Education
Education
Research
Publications
Teaching

Immune-mediated damage completes the parabola: Cryptococcus neoformans pathogenesis can reflect the outcome of a weak or strong immune response

Pirofski, L. A. & Casadevall, A., Nov 1 2017, In : mBio. 8, 6, e02063-17

Research output: Contribution to journalComment/debate

Cryptococcosis
Cryptococcus neoformans
Virulence
Fungi
Immunotherapy

Lipids affect the Cryptococcus neoformans-macrophage interaction and promote nonlytic exocytosis

Nolan, S. J., Fu, M. S., Coppens, I. & Casadevall, A. Jan 1 2017 In : Infection and Immunity. 85, 12, e00564-17

Research output: Contribution to journalArticle

Cryptococcus neoformans
Exocytosis
Macrophages
Lipids
Oleic Acid

Melanin, radiation, and energy transduction in fungi

Casadevall, A., Cordero, R. J. B., Bryan, R., Nosanchuk, J. & Dadachova, E., 2017, In : Microbiology spectrum. 5, 2, FUNK-0037-2016

Research output: Contribution to journalArticle

melanin
Melanins
Fungi
fungus
Radiation

Microbial melanins for radioprotection and bioremediation

Cordero, R. J. B., Vij, R. & Casadevall, A., Sep 1 2017, In : Microbial Biotechnology. 10, 5, p. 1186-1190 5 p.

Research output: Contribution to journalArticle

Melanin
Environmental Biodegradation
Bioremediation
Melanins
Technology

N-acetylglucosamine affects cryptococcus neoformans cell-wall composition and melanin architecture

Camacho, E., Chrissian, C., Cordero, R. J. B., Lopes, L. L., Stark, R. E. & Casadevall, A., Nov 1 2017, In : Microbiology (United Kingdom). 163, 11, p. 1540-1556 17 p., 000552

Research output: Contribution to journalArticle

Cryptococcus neoformans
Acetylglucosamine
Melanins
Cell Wall
Chitin
Cryptococcus neoformans
Fluconazole
Amphotericin B
Cryptococcal Meningitis
Saturn

Reply to argüelles and argüelles-prieto, “are the editors responsible for our obsession with the impact factor?”

Casadevall, A. & Fang, F. C., Nov 1 2017, In : mBio. 8, 6, e02079-17

Research output: Contribution to journalLetter

Obsessive Behavior

Reply to Engelthaler and Meyer, "Furthering the continental drift speciation hypothesis in the pathogenic Cryptococcus species complexes"

Casadevall, A., Freij, J. B., Hann-Soden, C. & Taylor, J. May 1 2017 In : mSphere. 2, 3, e00242-17

Research output: Contribution to journalLetter

Cryptococcus gattii
Cryptococcus

Reply to "on the impact factor and the ASM editorial policy"

Fang, F. C. & Casadevall, A., 2017, In : Infection and Immunity. 85, 2, e00989-16

Research output: Contribution to journalLetter

Editorial Policies

Support science by publishing in scientific society journals

Schloss, P. D., Johnston, M. & Casadevall, A., Sep 1 2017, In : mBio. 8, 5, e01633-17

Research output: Contribution to journalEditorial

Journal Impact Factor
Microbiology
Publications
Education
Pressure

The case for adopting the "species complex" nomenclature for the etiologic agents of cryptococcosis

Kwon-Chung, K. J. , Bennett, J. E. , Wickes, B. L. , Meyer, W. , Cuomo, C. A. , Wollenburg, K. R. , Bicanic, T. A. , Castañeda, E. , Chang, Y. C. , Chen, J. , Cogliati, M. , Dromer, F. , Ellis, D. , Filler, S. G. , Fisher, M. C. , Harrison, T. S. , Holland, S. M. , Kohno, S. , Kronstad, J. W. , Lazera, M. & 13 others Levitz, S. M., Lionakis, M. S., May, R. C., Ngamskulrongroj, P., Pappas, P. G., Perfect, J. R., Rickerts, V., Sorrell, T. C., Walsh, T. J., Williamson, P. R., Xu, J., Zelazny, A. M. & Casadevall, A., Jan 1 2017, In : mSphere. 2, 1, e00357-16

Research output: Contribution to journalArticle

Cryptococcus gattii
Cryptococcosis
Cryptococcus neoformans
Terminology
Animal Diseases

The mbio American academy of microbiology submission track in 2017

Casadevall, A. & Shenk, T., Jan 1 2017, In : mBio. 8, 1, e00050-17

Research output: Contribution to journalEditorial

Microbiology

The pathogenic potential of a microbe

Casadevall, A. Jan 1 2017 In : mSphere. 2, 1, e00015-17

Research output: Contribution to journalComment/debate

Virulence
Lethal Dose 50
Infection
Mortality
2016

Acknowledgement of reviewers

Casadevall, A., Mar 8 2016, In : mBio. 7, 2, e00195-16

Research output: Contribution to journalArticle