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2018

Analysis of predicted loss-of-function variants in UK Biobank identifies variants protective for disease

Emdin, C. A., Khera, A. V., Chaffin, M., Klarin, D., Natarajan, P., Aragam, K., Haas, M., Bick, A., Zekavat, S. M., Nomura, A., Ardissino, D., Wilson, J. G., Schunkert, H., McPherson, R., Watkins, H., Elosua, R., Bown, M. J., Samani, N. J., Baber, U., Erdmann, J. & 21 othersGupta, N., Danesh, J., Chasman, D., Ridker, P., Denny, J., Bastarache, L., Lichtman, J. H., D'Onofrio, G., Mattera, J., Spertus, J. A., Sheu, W. H. H., Taylor, K. D., Psaty, B. M., Rich, S. S., Post, W. S., Rotter, J. I., Chen, Y. D. I., Krumholz, H., Saleheen, D., Gabriel, S. & Kathiresan, S., Dec 1 2018, In : Nature Communications. 9, 1, 1613.

Research output: Contribution to journalArticle

genes
Genes
Body Fat Distribution
allergic diseases
Terminator Codon
Gonadal Steroid Hormones
Atherosclerosis
Coronary Vessels
Calcium
Cardiovascular Diseases

Carotid artery atherosclerosis is associated with mortality in HIV-positive women and men

Hanna, D. B., Moon, J. Y., Haberlen, S., French, A. L., Palella, F. J., Gange, S. J., Witt, M. D., Kassaye, S., Lazar, J. M., Tien, P. C., Feinstein, M. J., Kingsley, L. A., Post, W. S., Kaplan, R. C., Hodis, H. N. & Anastos, K., Oct 23 2018, In : AIDS (London, England). 32, 16, p. 2393-2403 11 p.

Research output: Contribution to journalArticle

Carotid Artery Diseases
Carotid Arteries
HIV
Mortality
Confidence Intervals

Carotid artery ultrasound texture, cardiovascular risk factors, and subclinical arterial disease: the Multi-Ethnic Study of Atherosclerosis (MESA)

Mitchell, C. C., Korcarz, C. E., Tattersall, M. C., Gepner, A. D., Young, R. L., Post, W. S., Kaufman, J. D., McClelland, R. L. & Stein, J. H., Apr 1 2018, In : The British journal of radiology. 91, 1084, 1 p.

Research output: Contribution to journalArticle

Carotid Arteries
Atherosclerosis
Cardiovascular Diseases
Carotid Intima-Media Thickness
Common Carotid Artery

Coronary Heart Disease Genetic Risk Score Predicts Cardiovascular Disease Risk in Men, Not Women

Hajek, C., Guo, X., Yao, J., Hai, Y., Johnson, W. C., Frazier-Wood, A. C., Post, W. S., Psaty, B. M., Taylor, K. D. & Rotter, J. I., Oct 1 2018, In : Circulation. Genomic and precision medicine. 11, 10, p. e002324

Research output: Contribution to journalLetter

Deep-coverage whole genome sequences and blood lipids among 16,324 individuals

NHLBI TOPMed Lipids Working Group, Dec 1 2018, In : Nature communications. 9, 1, 3391.

Research output: Contribution to journalArticle

sequencing
genome
cholesterol
lipoproteins
blood

Deep coverage whole genome sequences and plasma lipoprotein(a) in individuals of European and African ancestries

Zekavat, S. M., Ruotsalainen, S., Handsaker, R. E., Alver, M., Bloom, J., Poterba, T., Seed, C., Ernst, J., Chaffin, M., Engreitz, J., Peloso, G. M., Manichaikul, A., Yang, C., Ryan, K. A., Fu, M., Johnson, W. C., Tsai, M., Budoff, M., Ramachandran, V. S., Cupples, L. A. & 323 othersRotter, J. I., Rich, S. S., Post, W. S., Mitchell, B. D., Correa, A., Metspalu, A., Wilson, J. G., Salomaa, V., Kellis, M., Daly, M. J., Neale, B. M., McCarroll, S., Surakka, I., Esko, T., Ganna, A., Ripatti, S., Kathiresan, S., Natarajan, P., Abe, N., Abecasis, G., Albert, C., Allred, N. P., Almasy, L., Alonso, A., Ament, S., Anderson, P., Anugu, P., Applebaum-Bowden, D., Arking, D., Arnett, D. K., Ashley-Koch, A., Aslibekyan, S., Assimes, T., Auer, P., Avramopoulos, D., Barnard, J., Barnes, K., Barr, R. G., Barron-Casella, E., Beaty, T. L., Becker, D., Becker, L., Beer, R., Begum, F., Beitelshees, A., Benjamin, E., Bezerra, M., Bielak, L., Bis, J., Blackwell, T., Blangero, J., Boerwinkle, E., Borecki, I., Bowler, R., Brody, J., Broeckel, U., Broome, J., Bunting, K., Burchard, E., Cardwell, J., Carty, C., Casaburi, R., Casella, J. F., Chang, C., Chasman, D., Chavan, S., Chen, B. J., Chen, W. M., Chen, Y. D. I., Cho, M., Choi, S. H., Chuang, L. M., Chung, M., Cornell, E., Crandall, C., Crapo, J., Curran, J., Curtis, J., Custer, B., Damcott, C., Darbar, D., Das, S., David, S., Davis, C., Daya, M., Andrade, M. D., Debaun, M., Deka, R., Demeo, D., Devine, S., Do, R., Duan, Q., Duggirala, R., Durda, P., Dutcher, S., Eaton, C., Ekunwe, L., Ellinor, P., Emery, L., Farber, C., Farnam, L., Fingerlin, T., Flickinger, M., Fornage, M., Franceschini, N., Fullerton, S. M., Fulton, L., Gabriel, S., Gan, W., Gao, Y., Gass, M., Gelb, B., Geng, X., Germer, S., Gignoux, C., Gladwin, M., Glahn, D., Gogarten, S., Gong, D. W., Goring, H., Gu, C. C., Guan, Y., Guo, X., Haessler, J., Hall, M., Harris, D., Hawley, N., He, J., Heavner, B., Heckbert, S., Hernandez, R., Herrington, D., Hersh, C., Hidalgo, B., Hixson, J., Hokanson, J., Hong, E., Hoth, K., Hsiung, C., Huston, H., Hwu, C. M., Irvin, M. R., Jackson, R., Jain, D., Jaquish, C., Jhun, M. A., Johnsen, J., Johnson, A., Johnston, R., Jones, K., Kang, H. M., Kaplan, R., Kardia, S., Kaufman, L., Kelly, S., Kenny, E., Kessler, M., Khan, A., Kinney, G., Konkle, B., Kooperberg, C., Kramer, H., Krauter, S., Lange, C., Lange, E., Lange, L., Laurie, C., Laurie, C., Leboff, M., Lee, S. S., Lee, W. J., Lefaive, J., Levine, D., Levy, D., Lewis, J., Li, Y., Lin, H., Lin, K. H., Liu, S., Liu, Y., Loos, R., Lubitz, S., Lunetta, K., Luo, J., Mahaney, M., Make, B., Manson, J. A., Margolin, L., Martin, L., Mathai, S., Mathias, R., McArdle, P., McDonald, M. L., McFarland, S., McGarvey, S., Mei, H., Meyers, D. A., Mikulla, J., Min, N., Minear, M., Minster, R. L., Montasser, M. E., Musani, S., Mwasongwe, S., Mychaleckyj, J. C., Nadkarni, G., Naik, R. P., Nekhai, S., Nickerson, D., North, K., O'connell, J., O'connor, T., Ochs-Balcom, H., Pankow, J., Papanicolaou, G., Parker, M., Parsa, A., Penchev, S., Peralta, J. M., Perez, M., Perry, J., Peters, U., Peyser, P., Phillips, L., Phillips, S., Pollin, T., Becker, J. P., Boorgula, M. P., Preuss, M., Prokopenko, D., Psaty, B., Qasba, P., Qiao, D., Qin, Z., Rafaels, N., Raffield, L., Rao, D. C., Rasmussen-Torvik, L., Ratan, A., Redline, S., Reed, R., Regan, E., Reiner, A., Rice, K., Roden, D., Roselli, C., Ruczinski, I., Russell, P., Ruuska, S., Sakornsakolpat, P., Salimi, S., Salzberg, S. L., Sandow, K., Sankaran, V., Scheller, C., Schmidt, E., Schwander, K., Schwartz, D., Sciurba, F., Seidman, C., Sheehan, V., Shetty, A., Shetty, A., Sheu, W. H. H., Shoemaker, M. B., Silver, B., Silverman, E., Smith, J., Smith, J., Smith, N., Smith, T., Smoller, S., Snively, B., Sofer, T., Sotoodehnia, N., Stilp, A., Streeten, E., Sung, Y. J., Sylvia, J., Szpiro, A., Sztalryd, C., Taliun, D., Tang, H., Taub, M. A., Taylor, K., Taylor, S., Telen, M., Thornton, T. A., Tinker, L., Tirschwell, D., Tiwari, H., Tracy, R., Vaidya, D., Vandehaar, P., Vrieze, S., Walker, T., Wallace, R., Walts, A., Wan, E., Wang, F. F., Watson, K., Weeks, D. E., Weir, B., Weiss, S., Weng, L. C., Willer, C., Williams, K., Williams, L. K., Wilson, C., Wong, Q., Xu, H., Yanek, L., Yang, I., Yang, R., Zaghloul, N., Zhang, Y., Zhao, S. X., Zhao, W., Zheng, X., Zhi, D., Zhou, X., Zody, M. & Zoellner, S., Dec 1 2018, In : Nature communications. 9, 1, 2606.

Research output: Contribution to journalArticle

lipoproteins
Lipoprotein(a)
genome
Cardiovascular Diseases
Genes

Effects of Body Size and Composition on Sex Differences in Measured GFR in a US Community-Based Older Cohort (MESA-Kidney)

Abraham, A. G., Shafi, T., Tighiouart, H., Moseley, K., Post, W. S., Inker, L. A., Coresh, J., Shlipak, M. G. & Levey, A. S., Nov 1 2018, In : American Journal of Kidney Diseases. 72, 5, p. 767-770 4 p.

Research output: Contribution to journalLetter

Body Size
Body Composition
Sex Characteristics
Kidney

Endogenous Sex Hormones and Incident Cardiovascular Disease in Post-Menopausal Women

Zhao, D., Guallar, E., Ouyang, P., Subramanya, V., Vaidya, D., Ndumele, C. E., Lima, J., Allison, M. A., Shah, S. J., Bertoni, A. G., Budoff, M. J., Post, W. S. & Michos, E. D., Jun 5 2018, In : Journal of the American College of Cardiology. 71, 22, p. 2555-2566 12 p.

Research output: Contribution to journalArticle

Gonadal Steroid Hormones
Cardiovascular Diseases
Confidence Intervals
Coronary Disease
Testosterone
document markup languages
lipoproteins
Lipoprotein(a)
HTML
genome

Ethnic, geographic, and genetic differences in arsenic metabolism at low arsenic exposure: A preliminary analysis in the multi-ethnic study of atherosclerosis (mesa)

Balakrishnan, P., Jones, M., Vaidya, D., Tellez-Plaza, M., Post, W. S., Kaufman, J. D., Bielinski, S. J., Taylor, K., Francesconi, K., Goessler, W. & Navas Acien, A., Jun 5 2018, In : International Journal of Environmental Research and Public Health. 15, 6, 1179.

Research output: Contribution to journalArticle

Arsenic
Atherosclerosis
Cacodylic Acid
Seafood
Methyltransferases

Ethnic, geographic and dietary differences in arsenic exposure in the multi-ethnic study of atherosclerosis (MESA)

Jones, M., Tellez-Plaza, M., Vaidya, D., Grau-Perez, M., Post, W. S., Kaufman, J. D., Guallar, E., Francesconi, K. A., Goessler, W., Nachman, K., Sanchez, T. R. & Navas Acien, A., May 24 2018, (Accepted/In press) In : Journal of Exposure Science and Environmental Epidemiology. p. 1-13 13 p.

Research output: Contribution to journalArticle

Arsenic
Atherosclerosis
Urine
Wine
Hispanic Americans

Factors of health in the protection against death and cardiovascular disease among adults with subclinical atherosclerosis

Al Rifai, M., Greenland, P., Blaha, M., Michos, E. D., Nasir, K., Miedema, M. D., Yeboah, J., Sandfort, V., Frazier-Wood, A. C., Shea, S., Lima, J., Szklo, M., Post, W. S., Blumenthal, R. S. & McEvoy, J. W., Jan 1 2018, (Accepted/In press) In : American Heart Journal.

Research output: Contribution to journalArticle

Atherosclerosis
Cardiovascular Diseases
Coronary Vessels
Health
Calcium

Genome-Wide associations of global electrical heterogeneity ECG phenotype: The ARIC (Atherosclerosis Risk in Communities) study and CHS (Cardiovascular Health Study)

Tereshchenko, L. G., Sotoodehnia, N., Sitlani, C. M., Ashar, F. N., Kabir, M., Biggs, M. L., Morley, M. P., Waks, J. W., Soliman, E. Z., Buxton, A. E., Biering-Sørensen, T., Solomon, S. D., Post, W. S., Cappola, T. P., Siscovick, D. S. & Arking, D., Apr 17 2018, In : Journal of the American Heart Association. 7, 8, e008160.

Research output: Contribution to journalArticle

Atherosclerosis
Electrocardiography
Genome
Phenotype
Genetic Loci

Global ECG measures and cardiac structure and function the ARIC study (Atherosclerosis risk in communities)

Biering-Sørensen, T., Kabir, M., Waks, J. W., Thomas, J., Post, W. S., Soliman, E. Z., Buxton, A. E., Shah, A. M., Solomon, S. D. & Tereshchenko, L. G., Mar 1 2018, In : Circulation: Arrhythmia and Electrophysiology. 11, 3, e005961.

Research output: Contribution to journalArticle

Stroke Volume
Atherosclerosis
Electrocardiography
Confidence Intervals
Cardiovascular Diseases

Gut Microbial-Related Choline Metabolite Trimethylamine-N-Oxide Is Associated With Progression of Carotid Artery Atherosclerosis in HIV Infection

Shan, Z., Clish, C. B., Hua, S., Scott, J. M., Hanna, D. B., Burk, R. D., Haberlen, S., Shah, S. J., Margolick, J. B., Sears, C. L., Post, W. S., Landay, A. L., Lazar, J. M., Hodis, H. N., Anastos, K., Kaplan, R. C. & Qi, Q., Sep 22 2018, In : The Journal of infectious diseases. 218, 9, p. 1474-1479 6 p.

Research output: Contribution to journalArticle

Carotid Artery Diseases
Choline
Carotid Arteries
HIV Infections
HIV

GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes

MEGASTROKE Consortium, Dec 1 2018, In : Nature communications. 9, 1, 5141.

Research output: Contribution to journalArticle

Carotid Intima-Media Thickness
genome
Genome-Wide Association Study
loci
arteries

High-Density Lipoprotein Subspecies Defined by Presence of Apolipoprotein C-III and Incident Coronary Heart Disease in Four Cohorts

Jensen, M. K., Aroner, S. A., Mukamal, K. J., Furtado, J. D., Post, W. S., Tsai, M. Y., Tjønneland, A., Polak, J. F., Rimm, E. B., Overvad, K., McClelland, R. L. & Sacks, F. M., Mar 27 2018, In : Circulation. 137, 13, p. 1364-1373 10 p.

Research output: Contribution to journalArticle

Apolipoprotein C-III
HDL Lipoproteins
Coronary Disease
Apolipoprotein A-I
Confidence Intervals

Low thigh muscle mass is associated with coronary artery stenosis among HIV-infected and HIV-uninfected men: The Multicenter AIDS Cohort Study (MACS)

Tibuakuu, M., Zhao, D., Saxena, A., Brown, T. T., Jacobson, L. P., Palella, F. J., Witt, M. D., Koletar, S. L., Margolick, J. B., Guallar, E., Korada, S. K. C., Budoff, M. J., Post, W. S. & Michos, E. D., Jan 1 2018, (Accepted/In press) In : Journal of Cardiovascular Computed Tomography.

Research output: Contribution to journalArticle

Coronary Stenosis
Thigh
Acquired Immunodeficiency Syndrome
Cohort Studies
HIV

Lp-PLA2, scavenger receptor class B type i gene (SCARB1) rs10846744 variant, and cardiovascular disease

Manichaikul, A., Wang, X. Q., Li, L., Erdmann, J., Lettre, G., Bis, J. C., Waterworth, D., Cushman, M., Jenny, N. S., Post, W. S., Palmas, W., Tsai, M. Y., Wallentin, L., White, H., Schunkert, H., O'Donnell, C. J., Herrington, D. M., Rich, S. S., O'Donoghue, M. L. & Rodriguez-Oquendo, A., Oct 1 2018, In : PloS one. 13, 10, e0204352.

Research output: Contribution to journalArticle

Class B Scavenger Receptors
1-Alkyl-2-acetylglycerophosphocholine Esterase
cardiovascular diseases
atherosclerosis
Cardiovascular Diseases

Multicenter AIDS Cohort Study Quantitative Coronary Plaque Progression Study: Rationale and design

Nakanishi, R., Post, W. S., Osawa, K., Jayawardena, E., Kim, M., Sheidaee, N., Nezarat, N., Rahmani, S., Kim, N., Hathiramani, N., Susarla, S., Palella, F., Witt, M., Blaha, M., Brown, T. T., Kingsley, L., Haberlen, S., Dailing, C. & Budoff, M. J., Jan 1 2018, In : Coronary Artery Disease. 29, 1, p. 23-29 7 p.

Research output: Contribution to journalArticle

Acquired Immunodeficiency Syndrome
Cohort Studies
HIV
Coronary Artery Disease
Multicenter Studies

Multiethnic meta-analysis identifies RAI1 as a possible obstructive sleep apnea-related quantitative trait locus in men

Chen, H., Cade, B. E., Gleason, K. J., Bjonnes, A. C., Stilp, A. M., Sofer, T., Conomos, M. P., Ancoli-Israel, S., Arens, R., Azarbarzin, A., Bell, G. I., Below, J. E., Chun, S., Evans, D. S., Ewert, R., Frazier-Wood, A. C., Gharib, S. A., Haba-Rubio, J., Hagen, E. W., Heinzer, R. & 42 othersHillman, D. R., Craig Johnson, W., Kutalik, Z., Lane, J. M., Larkin, E. K., Lee, S. K., Liang, J., Loredo, J. S., Mukherjee, S., Palmer, L. J., Papanicolaou, G. J., Penzel, T., Peppard, P. E., Post, W. S., Ramos, A. R., Rice, K., Rotter, J. I., Sands, S. A., Shah, N. A., Shin, C., Stone, K. L., Stubbe, B., Sul, J. H., Tafti, M., Taylor, K. D., Teumer, A., Thornton, T. A., Tranah, G. J., Wang, C., Wang, H., Warby, S. C., Andrew Wellman, D., Zee, P. C., Hanis, C. L., Laurie, C. C., Gottlieb, D. J., Patel, S. R., Zhu, X., Sunyaev, S. R., Saxena, R., Lin, X. & Redline, S., Mar 1 2018, In : American Journal of Respiratory Cell and Molecular Biology. 58, 3, p. 391-401 11 p.

Research output: Contribution to journalEditorial

Phosphatidylethanolamine N-Methyltransferase
Sterol Regulatory Element Binding Protein 1
ras Proteins
Transcription Factors
Eye movements

Observational and Genetic Associations of Resting Heart Rate With Aortic Valve Calcium

Whelton, S., Mauer, A. C., Pencina, K. M., Massaro, J. M., D'Agostino, R. B., Fox, C. S., Hoffmann, U., Michos, E. D., Peloso, G. M., Dufresne, L., Engert, J. C., Kathiresan, S., Budoff, M., Post, W. S., Thanassoulis, G. & O'Donnell, C. J., Jan 1 2018, (Accepted/In press) In : American Journal of Cardiology.

Research output: Contribution to journalArticle

Aortic Valve
Heart Rate
Calcium
Cohort Studies
Atherosclerosis

Performance of glomerular filtration rate estimating equations in a community-based sample of Blacks and Whites: The multiethnic study of atherosclerosis

Inker, L. A., Levey, A. S., Tighiouart, H., Shafi, T., Eckfeldt, J. H., Johnson, C., Okparavero, A., Post, W. S., Coresh, J. & Shlipak, M. G., Mar 1 2018, In : Nephrology Dialysis Transplantation. 33, 3, p. 417-425 9 p.

Research output: Contribution to journalArticle

Glomerular Filtration Rate
Atherosclerosis
Chronic Renal Insufficiency
Epidemiology
Cystatin C

Plasma tryptophan-kynurenine metabolites are altered in human immunodeficiency virus infection and associated with progression of carotid artery atherosclerosis

Qi, Q., Hua, S., Clish, C. B., Scott, J. M., Hanna, D. B., Wang, T., Haberlen, S., Shah, S. J., Glesby, M. J., Lazar, J. M., Burk, R. D., Hodis, H. N., Landay, A. L., Post, W. S., Anastos, K. & Kaplan, R. C., Jul 2 2018, In : Clinical Infectious Diseases. 67, 2, p. 235-242 8 p.

Research output: Contribution to journalArticle

Kynurenine
Carotid Artery Diseases
Kynurenic Acid
Virus Diseases
Carotid Arteries

Predictors of electrocardiographic QT interval prolongation in men with HIV

Wu, K. C-C., Zhang, L., Haberlen, S., Ashikaga, H., Brown, T. T., Budoff, M. J., D'Souza, G., Kingsley, L. A., Palella, F. J., Margolick, J. B., Martínez-Maza, O., Soliman, E. Z. & Post, W. S., Jan 1 2018, (Accepted/In press) In : Heart.

Research output: Contribution to journalArticle

HIV
Sudden Cardiac Death
Biomarkers
B-Cell Activating Factor
Intercellular Adhesion Molecule-1

Progression of calcium density in the ascending thoracic aorta is inversely associated with incident cardiovascular disease events

Thomas, I. C., McClelland, R. L., Allison, M. A., Ix, J. H., Michos, E. D., Forbang, N. I., Post, W. S., Wong, N. D., Budoff, M. J. & Criqui, M. H., Dec 1 2018, In : European heart journal cardiovascular Imaging. 19, 12, p. 1343-1350 8 p.

Research output: Contribution to journalArticle

Thoracic Aorta
Aorta
Cardiovascular Diseases
Calcium
Confidence Intervals

Rare loss of function variants in candidate genes and risk of colorectal cancer

NHLBI GO Exome Sequencing Project, Pulmonary Arterial Hypertension (PAH), Severe Asthma Research Program (SARP), Women’s Health Initiative (WHI), Anthropometry Project Team, Blood Count/Hematology Project Team, Blood Pressure Project Team, Data Flow Working Group, Early MI Project Team, ELSI Working Group, Executive Committee, Family Study Project Team, Lipids Project Team, Lung Project Team, Personal Genomics Project Team, Phenotype and Harmonization Working Group, Population Genetics and Statistical Analysis Working Group, Publications and Presentations Working Group, Quantitative Analysis Ad Hoc Task Group, Sequencing and Genotyping Working Group & 15 othersSteering Committee, Stroke Project Team, Structural Variation Working Group, Subclinical/Quantitative Project Team, Acute Lung Injury (ALI), Atherosclerosis Risk in Communities (ARIC), Cardiovascular Health Study (CHS), Chronic Obstructive Pulmonary Disease (COPDGene), Coronary Artery Risk Development in Young Adults (CARDIA), Cystic Fibrosis (CF), Early Pseudomonas Infection Control (EPIC), Framingham Heart Study (FHS), Jackson Heart Study (JHS), Lung Health Study (LHS) & Multi-Ethnic Study of Atherosclerosis (MESA), Oct 1 2018, In : Human genetics. 137, 10, p. 795-806 12 p.

Research output: Contribution to journalArticle

Polyps
Colorectal Neoplasms
Genes
Penetrance
Genetic Testing

Relation of Sex Hormone Levels with Prevalent and 10-Year Change in Aortic Distensibility Assessed by MRI: The Multi-Ethnic Study of Atherosclerosis

Subramanya, V., Ambale Venkatesh, B., Ohyama, Y., Zhao, D., Nwabuo, C. C., Post, W. S., Guallar, E., Ouyang, P., Shah, S. J., Allison, M. A., Ndumele, C. E., Vaidya, D., Bluemke, D. A., Lima, J. & Michos, E. D., Jun 11 2018, In : American Journal of Hypertension. 31, 7, p. 774-783 10 p.

Research output: Contribution to journalArticle

Gonadal Steroid Hormones
Atherosclerosis
Testosterone
Estradiol
Magnetic Resonance Imaging

Resting heart rate and the incidence and progression of valvular calcium: The Multi-Ethnic Study of Atherosclerosis (MESA)

Amoakwa, K., Fashanu, O. E., Tibuakuu, M., Zhao, D., Guallar, E., Whelton, S., O'Neal, W. T., Post, W. S., Budoff, M. J. & Michos, E. D., Jun 1 2018, In : Atherosclerosis. 273, p. 45-52 8 p.

Research output: Contribution to journalArticle

Atherosclerosis
Heart Rate
Calcium
Incidence
Aortic Valve

Risk factors for progression of coronary artery calcification in patients with chronic kidney disease: The CRIC study

the CRIC Study Investigators, Apr 1 2018, In : Atherosclerosis. 271, p. 53-60 8 p.

Research output: Contribution to journalArticle

Chronic Renal Insufficiency
Coronary Vessels
Cohort Studies
Cardiovascular Diseases
Cystatin C

Sex hormone levels and change in left ventricular structure among men and post-menopausal women: The Multi-Ethnic Study of Atherosclerosis (MESA)

Subramanya, V., Zhao, D., Ouyang, P., Lima, J., Vaidya, D., Ndumele, C. E., Bluemke, D. A., Shah, S. J., Guallar, E., Nwabuo, C. C., Allison, M. A., Heckbert, S. R., Post, W. S. & Michos, E. D., Feb 1 2018, In : Maturitas. 108, p. 37-44 8 p.

Research output: Contribution to journalArticle

Gonadal Steroid Hormones
Sex Hormone-Binding Globulin
Atherosclerosis
Testosterone
Magnetic resonance

Sex Hormones and Change in N-Terminal Pro-B-Type Natriuretic Peptide Levels: The Multi-Ethnic Study of Atherosclerosis

Ying, W., Zhao, D., Ouyang, P., Subramanya, V., Vaidya, D., Ndumele, C. E., Sharma, K., Shah, S. J., Heckbert, S. R., Lima, J., deFilippi, C. R., Budoff, M. J., Post, W. S. & Michos, E. D., Nov 1 2018, In : The Journal of clinical endocrinology and metabolism. 103, 11, p. 4304-4314 11 p.

Research output: Contribution to journalArticle

Brain Natriuretic Peptide
Gonadal Steroid Hormones
Atherosclerosis
Cardiovascular Diseases
Dehydroepiandrosterone

Systemic Inflammation Characterizes Lack of Metabolic Health in Nonobese HIV-Infected Men

Monczor, A. N., Li, X., Palella, F. J., Erlandson, K. M., Wiley, D., Kingsley, L. A., Post, W. S., Jacobson, L. P., Brown, T. T. & Lake, J. E., Jan 1 2018, In : Mediators of inflammation. 2018, 1 p.

Research output: Contribution to journalArticle

HIV
Inflammation
Health
Adiponectin
Insulin Resistance

Ten-year association of coronary artery calcium with atherosclerotic cardiovascular disease (ASCVD) events: the multi-ethnic study of atherosclerosis (MESA)

Budoff, M. J., Young, R., Burke, G., Carr, J. J., Detrano, R. C., Folsom, A. R., Kronmal, R., Lima, J., Liu, K. J., McClelland, R. L., Michos, E. D., Post, W. S., Shea, S., Watson, K. E. & Wong, N. D., Jul 1 2018, In : European Heart Journal. 39, 25, p. 2401b-2408b

Research output: Contribution to journalArticle

Atherosclerosis
Coronary Vessels
Cardiovascular Diseases
Calcium
Coronary Disease

To T or not to T: Differences in Testosterone Use and Discontinuation by HIV Serostatus among Men who Have Sex with Men

Haberlen, S., Jacobson, L. P., Palella, F. J., Dobs, A. S., Plankey, M., Lake, J. E., Kingsley, L. A., Stall, R., Post, W. S. & Brown, T. T., Oct 1 2018, In : HIV Medicine. 19, 9, p. 634-644 11 p.

Research output: Contribution to journalArticle

Testosterone
HIV
Cardiovascular Diseases
Therapeutics
Los Angeles

Ultrasound carotid plaque features, cardiovascular disease risk factors and events: The Multi-Ethnic Study of Atherosclerosis

Mitchell, C., Korcarz, C. E., Gepner, A. D., Kaufman, J. D., Post, W. S., Tracy, R., Gassett, A. J., Ma, N., McClelland, R. L. & Stein, J. H., Jan 1 2018, (Accepted/In press) In : Atherosclerosis.

Research output: Contribution to journalArticle

Atherosclerosis
Cardiovascular Diseases
Coronary Disease
Coronary Vessels
Calcium
2017

Admixture Mapping of Subclinical Atherosclerosis and Subsequent Clinical Events among African Americans in 2 Large Cohort Studies

Shendre, A., Wiener, H., Irvin, M. R., Zhi, D., Limdi, N. A., Overton, E. T., Wassel, C. L., Divers, J., Rotter, J. I., Post, W. S. & Shrestha, S., Apr 1 2017, In : Circulation: Cardiovascular Genetics. 10, 2, e001569.

Research output: Contribution to journalArticle

Carotid Intima-Media Thickness
Common Carotid Artery
African Americans
Atherosclerosis
Cohort Studies

Assessment of coronary artery calcium by chest CT compared with EKG-gated cardiac CT in the multicenter AIDS cohort study

Chandra, D., Gupta, A., Leader, J. K., Fitzpatrick, M., Kingsley, L. A., Kleerup, E., Haberlen, S., Budoff, M. J., Witt, M., Post, W. S., Sciurba, F. C. & Morris, A., Apr 1 2017, In : PLoS One. 12, 4, e0176557.

Research output: Contribution to journalArticle

electrocardiography
coronary vessels
chest
cohort studies
Electrocardiography

Association between APOL1 genotypes and risk of cardiovascular disease in MESA (Multi-Ethnic Study of Atherosclerosis)

Chen, T., Katz, R., Estrella, M. M., Gutierrez, O. M., Kramer, H., Post, W. S., Shlipak, M. G., Wassel, C. L. & Peralta, C. A., Dec 1 2017, In : Journal of the American Heart Association. 6, 12, e007199.

Research output: Contribution to journalArticle

Atherosclerosis
Cardiovascular Diseases
Genotype
Heart Failure
Confidence Intervals

Association of Cardiovascular Health With Subclinical Disease and Incident Events: The Multi-Ethnic Study of Atherosclerosis

Polonsky, T. S., Ning, H., Daviglus, M. L., Liu, K., Burke, G. L., Cushman, M., Eng, J., Folsom, A. R., Lutsey, P. L., Nettleton, J. A., Post, W. S., Sacco, R. L., Szklo, M. & Lloyd-Jones, D. M., Mar 1 2017, In : Journal of the American Heart Association. 6, 3, e004894.

Research output: Contribution to journalArticle

Atherosclerosis
Health
Cardiovascular Diseases
Carotid Intima-Media Thickness
Coronary Vessels

Association of macrophage inflammation biomarkers with progression of subclinical carotid artery atherosclerosis in HIV-infected women and men

Hanna, D. B., Lin, J., Post, W. S., Hodis, H. N., Xue, X., Anastos, K., Cohen, M. H., Gange, S. J., Haberlen, S., Heath, S. L., Lazar, J. M., Liu, C., Mack, W. J., Ofotokun, I., Palella, F. J., Tien, P. C., Witt, M. D., Landay, A. L., Kingsley, L. A., Tracy, R. P. & 1 othersKaplan, R. C., 2017, In : Journal of Infectious Diseases. 215, 9, p. 1352-1361 10 p.

Research output: Contribution to journalArticle

Carotid Artery Diseases
Carotid Arteries
Biomarkers
Macrophages
HIV

Association of Triglyceride-Related Genetic Variants With Mitral Annular Calcification

CHARGE Extracoronary Calcium Working Group, Jun 20 2017, In : Journal of the American College of Cardiology. 69, 24, p. 2941-2948 8 p.

Research output: Contribution to journalArticle

Triglycerides
Calcium
Atherosclerosis
Odds Ratio
Confidence Intervals

Associations of Coffee, Tea, and Caffeine Intake with Coronary Artery Calcification and Cardiovascular Events

Miller, P. E., Zhao, D., Frazier-Wood, A. C., Michos, E. D., Averill, M., Sandfort, V., Burke, G. L., Polak, J. F., Lima, J., Post, W. S., Blumenthal, R. S., Guallar, E. & Martin, S., Feb 1 2017, In : American Journal of Medicine. 130, 2, p. 188-197.e5

Research output: Contribution to journalArticle

Coffee
Tea
Caffeine
Coronary Vessels
Calcium

Blood monocyte transcriptome and epigenome analyses reveal loci associated with human atherosclerosis

Liu, Y., Reynolds, L. M., Ding, J., Hou, L., Lohman, K., Young, T., Cui, W., Huang, Z., Grenier, C., Wan, M., Stunnenberg, H. G., Siscovick, D., Hou, L., Psaty, B. M., Rich, S. S., Rotter, J. I., Kaufman, J. D., Burke, G. L., Murphy, S., Jacobs, D. R. & 8 othersPost, W. S., Hoeschele, I., Bell, D. A., Herrington, D., Parks, J. S., Tracy, R. P., McCall, C. E. & Stein, J. H., Dec 1 2017, In : Nature Communications. 8, 1, 393.

Research output: Contribution to journalArticle

monocytes
arteriosclerosis
Methylation
Gene Expression Profiling
loci

Causal effect of plasminogen activator inhibitor type 1 on coronary heart disease

CHARGE Consortium Hemostatic Factor Working Group, ICBP Consortium & CHARGE Consortium Subclinical Working Group, Jun 1 2017, In : Journal of the American Heart Association. 6, 6, e004918.

Research output: Contribution to journalArticle

Plasminogen Activator Inhibitor 1
Coronary Disease
Odds Ratio
Mendelian Randomization Analysis
Genome-Wide Association Study

Comparison of carotid plaque score and coronary artery calcium score for predicting cardiovascular disease events: The multi-ethnic study of atherosclerosis

Gepner, A. D., Young, R., Delaney, J. A., Budoff, M. J., Polak, J. F., Blaha, M., Post, W. S., Michos, E. D., Kaufman, J. & Stein, J. H., 2017, In : Journal of the American Heart Association. 6, 2, e005179.

Research output: Contribution to journalArticle

Atherosclerosis
Coronary Vessels
Cardiovascular Diseases
Transient Ischemic Attack
Calcium

Density of calcium in the ascending thoracic aorta and risk of incident cardiovascular disease events

Thomas, I. C., McClelland, R. L., Michos, E. D., Allison, M. A., Forbang, N. I., Longstreth, W. T., Post, W. S., Wong, N. D., Budoff, M. J. & Criqui, M. H., Oct 1 2017, In : Atherosclerosis. 265, p. 190-196 7 p.

Research output: Contribution to journalArticle

Thoracic Aorta
Aorta
Cardiovascular Diseases
Calcium
Coronary Vessels

Evaluation of lipoprotein(a) electrophoretic and immunoassay methods in discriminating risk of calcific aortic valve disease and incident coronary heart disease: The multi-ethnic study of atherosclerosis

Cao, J., Steffen, B. T., Guan, W., Budoff, M., Michos, E. D., Kizer, J. R., Post, W. S. & Tsai, M. Y., Nov 1 2017, In : Clinical Chemistry. 63, 11, p. 1705-1713 9 p.

Research output: Contribution to journalArticle

Aortic Diseases
Lipoprotein(a)
Aortic Valve
Immunoassay
Coronary Disease

Fine mapping of QT interval regions in global populations refines previously identified QT interval loci and identifies signals unique to African and Hispanic descent populations

Avery, C. L., Wassel, C. L., Richard, M. A., Highland, H. M., Bien, S., Zubair, N., Soliman, E. Z., Fornage, M., Bielinski, S. J., Tao, R., Seyerle, A. A., Shah, S. J., Lloyd-Jones, D. M., Buyske, S., Rotter, J. I., Post, W. S., Rich, S. S., Hindorff, L. A., Jeff, J. M., Shohet, R. V. & 8 othersSotoodehnia, N., Lin, D. Y., Whitsel, E. A., Peters, U., Haiman, C. A., Crawford, D. C., Kooperberg, C. & North, K. E., Apr 1 2017, In : Heart Rhythm. 14, 4, p. 572-580 9 p.

Research output: Contribution to journalArticle

Hispanic Americans
Single Nucleotide Polymorphism
Population
Genome-Wide Association Study
Biodiversity