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2018

Analysis of predicted loss-of-function variants in UK Biobank identifies variants protective for disease

Emdin, C. A. , Khera, A. V. , Chaffin, M. , Klarin, D. , Natarajan, P. , Aragam, K. , Haas, M. , Bick, A. , Zekavat, S. M. , Nomura, A. , Ardissino, D. , Wilson, J. G. , Schunkert, H. , McPherson, R. , Watkins, H. , Elosua, R. , Bown, M. J. , Samani, N. J. , Baber, U. , Erdmann, J. & 21 others Gupta, N., Danesh, J., Chasman, D., Ridker, P., Denny, J., Bastarache, L., Lichtman, J. H., D'Onofrio, G., Mattera, J., Spertus, J. A., Sheu, W. H. H., Taylor, K. D., Psaty, B. M., Rich, S. S., Post, W., Rotter, J. I., Chen, Y. D. I., Krumholz, H., Saleheen, D., Gabriel, S. & Kathiresan, S., Dec 1 2018, In : Nature Communications. 9, 1, 1613

Research output: Contribution to journalArticle

genes
Genes
Body Fat Distribution
allergic diseases
Terminator Codon

Carotid artery ultrasound texture, cardiovascular risk factors, and subclinical arterial disease: the Multi-Ethnic Study of Atherosclerosis (MESA)

Mitchell, C. C., Korcarz, C. E., Tattersall, M. C., Gepner, A. D., Young, R. L., Post, W. S., Kaufman, J. D., McClelland, R. L. & Stein, J. H., Apr 1 2018, In : The British journal of radiology. 91, 1084, 1 p.

Research output: Contribution to journalArticle

Carotid Arteries
Atherosclerosis
Cardiovascular Diseases
Carotid Intima-Media Thickness
Common Carotid Artery

Deep coverage whole genome sequences and plasma lipoprotein(a) in individuals of European and African ancestries

Zekavat, S. M. , Ruotsalainen, S. , Handsaker, R. E. , Alver, M. , Bloom, J. , Poterba, T. , Seed, C. , Ernst, J. , Chaffin, M. , Engreitz, J. , Peloso, G. M. , Manichaikul, A. , Yang, C. , Ryan, K. A. , Fu, M. , Johnson, W. C. , Tsai, M. , Budoff, M. , Ramachandran, V. S. , Cupples, L. A. & 323 others Rotter, J. I., Rich, S. S., Post, W., Mitchell, B. D., Correa, A., Metspalu, A., Wilson, J. G., Salomaa, V., Kellis, M., Daly, M. J., Neale, B. M., McCarroll, S., Surakka, I., Esko, T., Ganna, A., Ripatti, S., Kathiresan, S., Natarajan, P., Abe, N., Abecasis, G., Albert, C., Allred, N. P., Almasy, L., Alonso, A., Ament, S., Anderson, P., Anugu, P., Applebaum-Bowden, D., Arking, D., Arnett, D. K., Ashley-Koch, A., Aslibekyan, S., Assimes, T., Auer, P., Avramopoulos, D., Barnard, J., Barnes, K., Barr, R. G., Barron-Casella, E., Beaty, T., Becker, D., Becker, L., Beer, R., Begum, F., Beitelshees, A., Benjamin, E., Bezerra, M., Bielak, L., Bis, J., Blackwell, T., Blangero, J., Boerwinkle, E., Borecki, I., Bowler, R., Brody, J., Broeckel, U., Broome, J., Bunting, K., Burchard, E., Cardwell, J., Carty, C., Casaburi, R., Casella, J., Chang, C., Chasman, D., Chavan, S., Chen, B. J., Chen, W. M., Chen, Y. D. I., Cho, M., Choi, S. H., Chuang, L. M., Chung, M., Cornell, E., Crandall, C., Crapo, J., Curran, J., Curtis, J., Custer, B., Damcott, C., Darbar, D., Das, S., David, S., Davis, C., Daya, M., Andrade, M. D., Debaun, M., Deka, R., Demeo, D., Devine, S., Do, R., Duan, Q., Duggirala, R., Durda, P., Dutcher, S., Eaton, C., Ekunwe, L., Ellinor, P., Emery, L., Farber, C., Farnam, L., Fingerlin, T., Flickinger, M., Fornage, M., Franceschini, N., Fullerton, S. M., Fulton, L., Gabriel, S., Gan, W., Gao, Y., Gass, M., Gelb, B., Geng, X., Germer, S., Gignoux, C., Gladwin, M., Glahn, D., Gogarten, S., Gong, D. W., Goring, H., Gu, C. C., Guan, Y., Guo, X., Haessler, J., Hall, M., Harris, D., Hawley, N., He, J., Heavner, B., Heckbert, S., Hernandez, R., Herrington, D., Hersh, C., Hidalgo, B., Hixson, J., Hokanson, J., Hong, E., Hoth, K., Hsiung, C., Huston, H., Hwu, C. M., Irvin, M. R., Jackson, R., Jain, D., Jaquish, C., Jhun, M. A., Johnsen, J., Johnson, A., Johnston, R., Jones, K., Kang, H. M., Kaplan, R., Kardia, S., Kaufman, L., Kelly, S., Kenny, E., Kessler, M., Khan, A., Kinney, G., Konkle, B., Kooperberg, C., Kramer, H., Krauter, S., Lange, C., Lange, E., Lange, L., Laurie, C., Laurie, C., Leboff, M., Lee, S. S., Lee, W. J., Lefaive, J., Levine, D., Levy, D., Lewis, J., Li, Y., Lin, H., Lin, K. H., Liu, S., Liu, Y., Loos, R., Lubitz, S., Lunetta, K., Luo, J., Mahaney, M., Make, B., Manson, J. A., Margolin, L., Martin, L., Mathai, S., Mathias, R., McArdle, P., McDonald, M. L., McFarland, S., McGarvey, S., Mei, H., Meyers, D. A., Mikulla, J., Min, N., Minear, M., Minster, R. L., Montasser, M. E., Musani, S., Mwasongwe, S., Mychaleckyj, J. C., Nadkarni, G., Naik, R., Nekhai, S., Nickerson, D., North, K., O'connell, J., O'connor, T., Ochs-Balcom, H., Pankow, J., Papanicolaou, G., Parker, M., Parsa, A., Penchev, S., Peralta, J. M., Perez, M., Perry, J., Peters, U., Peyser, P., Phillips, L., Phillips, S., Pollin, T., Becker, J. P., Boorgula, M. P., Preuss, M., Prokopenko, D., Psaty, B., Qasba, P., Qiao, D., Qin, Z., Rafaels, N., Raffield, L., Rao, D. C., Rasmussen-Torvik, L., Ratan, A., Redline, S., Reed, R., Regan, E., Reiner, A., Rice, K., Roden, D., Roselli, C., Ruczinski, I., Russell, P., Ruuska, S., Sakornsakolpat, P., Salimi, S., Salzberg, S., Sandow, K., Sankaran, V., Scheller, C., Schmidt, E., Schwander, K., Schwartz, D., Sciurba, F., Seidman, C., Sheehan, V., Shetty, A., Shetty, A., Sheu, W. H. H., Shoemaker, M. B., Silver, B., Silverman, E., Smith, J., Smith, J., Smith, N., Smith, T., Smoller, S., Snively, B., Sofer, T., Sotoodehnia, N., Stilp, A., Streeten, E., Sung, Y. J., Sylvia, J., Szpiro, A., Sztalryd, C., Taliun, D., Tang, H., Taub, M., Taylor, K., Taylor, S., Telen, M., Thornton, T. A., Tinker, L., Tirschwell, D., Tiwari, H., Tracy, R., Vaidya, D., Vandehaar, P., Vrieze, S., Walker, T., Wallace, R., Walts, A., Wan, E., Wang, F. F., Watson, K., Weeks, D. E., Weir, B., Weiss, S., Weng, L. C., Willer, C., Williams, K., Williams, L. K., Wilson, C., Wong, Q., Xu, H., Yanek, L., Yang, I., Yang, R., Zaghloul, N., Zhang, Y., Zhao, S. X., Zhao, W., Zheng, X., Zhi, D., Zhou, X., Zody, M. & Zoellner, S., Dec 1 2018, In : Nature communications. 9, 1, 2606

Research output: Contribution to journalArticle

lipoproteins
Lipoprotein(a)
genome
Cardiovascular Diseases
cholesterol

Endogenous Sex Hormones and Incident Cardiovascular Disease in Post-Menopausal Women

Zhao, D., Guallar, E., Ouyang, P., Subramanya, V., Vaidya, D., Ndumele, C. E., Lima, J. A., Allison, M. A., Shah, S. J., Bertoni, A. G., Budoff, M. J., Post, W. S. & Michos, E. D., Jun 5 2018, In : Journal of the American College of Cardiology. 71, 22, p. 2555-2566 12 p.

Research output: Contribution to journalArticle

Gonadal Steroid Hormones
Cardiovascular Diseases
Confidence Intervals
Coronary Disease
Testosterone

Ethnic, geographic, and genetic differences in arsenic metabolism at low arsenic exposure: A preliminary analysis in the multi-ethnic study of atherosclerosis (mesa)

Balakrishnan, P., Jones, M. R., Vaidya, D., Tellez-Plaza, M., Post, W. S., Kaufman, J. D., Bielinski, S. J., Taylor, K., Francesconi, K., Goessler, W. & Navas-Acien, A., Jun 5 2018, In : International Journal of Environmental Research and Public Health. 15, 6, 1179

Research output: Contribution to journalArticle

arsenic
metabolism
ethnicity
analysis
exposure

Ethnic, geographic and dietary differences in arsenic exposure in the multi-ethnic study of atherosclerosis (MESA)

Jones, M. R., Tellez-Plaza, M., Vaidya, D., Grau-Perez, M., Post, W. S., Kaufman, J. D., Guallar, E., Francesconi, K. A., Goessler, W., Nachman, K. E., Sanchez, T. R. & Navas-Acien, A., May 24 2018, (Accepted/In press) In : Journal of Exposure Science and Environmental Epidemiology. p. 1-13 13 p.

Research output: Contribution to journalArticle

Arsenic
Amino acids
Atherosclerosis
Urine
Wine

Factors of health in the protection against death and cardiovascular disease among adults with subclinical atherosclerosis

Al Rifai, M., Greenland, P., Blaha, M. J., Michos, E. D., Nasir, K., Miedema, M. D., Yeboah, J., Sandfort, V., Frazier-Wood, A. C., Shea, S., Lima, J. A. C., Szklo, M., Post, W. S., Blumenthal, R. S. & McEvoy, J. W., Jan 1 2018, (Accepted/In press) In : American Heart Journal.

Research output: Contribution to journalArticle

Atherosclerosis
Cardiovascular Diseases
Coronary Vessels
Health
Calcium

Genome-Wide associations of global electrical heterogeneity ECG phenotype: The ARIC (Atherosclerosis Risk in Communities) study and CHS (Cardiovascular Health Study)

Tereshchenko, L. G., Sotoodehnia, N., Sitlani, C. M., Ashar, F. N., Kabir, M., Biggs, M. L., Morley, M. P., Waks, J. W., Soliman, E. Z., Buxton, A. E., Biering-Sørensen, T., Solomon, S. D., Post, W. S., Cappola, T. P., Siscovick, D. S. & Arking, D. E., Apr 17 2018, In : Journal of the American Heart Association. 7, 8, e008160

Research output: Contribution to journalArticle

Atherosclerosis
Electrocardiography
Genome
Phenotype
Genetic Loci

Global ECG measures and cardiac structure and function the ARIC study (Atherosclerosis risk in communities)

Biering-Sørensen, T., Kabir, M., Waks, J. W., Thomas, J., Post, W. S., Soliman, E. Z., Buxton, A. E., Shah, A. M., Solomon, S. D. & Tereshchenko, L. G., Mar 1 2018, In : Circulation: Arrhythmia and Electrophysiology. 11, 3, e005961

Research output: Contribution to journalArticle

Stroke Volume
Atherosclerosis
Electrocardiography
Confidence Intervals
Cardiovascular Diseases

High-Density Lipoprotein Subspecies Defined by Presence of Apolipoprotein C-III and Incident Coronary Heart Disease in Four Cohorts

Jensen, M. K., Aroner, S. A., Mukamal, K. J., Furtado, J. D., Post, W. S., Tsai, M. Y., Tjønneland, A., Polak, J. F., Rimm, E. B., Overvad, K., McClelland, R. L. & Sacks, F. M., Mar 27 2018, In : Circulation. 137, 13, p. 1364-1373 10 p.

Research output: Contribution to journalArticle

Apolipoprotein C-III
HDL Lipoproteins
Coronary Disease
Apolipoprotein A-I
Confidence Intervals

Low thigh muscle mass is associated with coronary artery stenosis among HIV-infected and HIV-uninfected men: The Multicenter AIDS Cohort Study (MACS)

Tibuakuu, M., Zhao, D., Saxena, A., Brown, T. T., Jacobson, L. P., Palella, F. J., Witt, M. D., Koletar, S. L., Margolick, J. B., Guallar, E., Korada, S. K. C., Budoff, M. J., Post, W. S. & Michos, E. D., Jan 1 2018, (Accepted/In press) In : Journal of Cardiovascular Computed Tomography.

Research output: Contribution to journalArticle

Sarcopenia
Coronary Stenosis
Thigh
HIV Infections
Coronary Artery Disease

Multicenter AIDS Cohort Study Quantitative Coronary Plaque Progression Study: Rationale and design

Nakanishi, R., Post, W. S., Osawa, K., Jayawardena, E., Kim, M., Sheidaee, N., Nezarat, N., Rahmani, S., Kim, N., Hathiramani, N., Susarla, S., Palella, F., Witt, M., Blaha, M. J., Brown, T. T., Kingsley, L., Haberlen, S. A., Dailing, C. & Budoff, M. J., Jan 1 2018, In : Coronary Artery Disease. 29, 1, p. 23-29 7 p.

Research output: Contribution to journalArticle

Acquired Immunodeficiency Syndrome
Cohort Studies
HIV
Coronary Artery Disease
Multicenter Studies

Multiethnic meta-analysis identifies RAI1 as a possible obstructive sleep apnea-related quantitative trait locus in men

Chen, H. , Cade, B. E. , Gleason, K. J. , Bjonnes, A. C. , Stilp, A. M. , Sofer, T. , Conomos, M. P. , Ancoli-Israel, S. , Arens, R. , Azarbarzin, A. , Bell, G. I. , Below, J. E. , Chun, S. , Evans, D. S. , Ewert, R. , Frazier-Wood, A. C. , Gharib, S. A. , Haba-Rubio, J. , Hagen, E. W. , Heinzer, R. & 42 others Hillman, D. R., Craig Johnson, W., Kutalik, Z., Lane, J. M., Larkin, E. K., Lee, S. K., Liang, J., Loredo, J. S., Mukherjee, S., Palmer, L. J., Papanicolaou, G. J., Penzel, T., Peppard, P. E., Post, W. S., Ramos, A. R., Rice, K., Rotter, J. I., Sands, S. A., Shah, N. A., Shin, C., Stone, K. L., Stubbe, B., Sul, J. H., Tafti, M., Taylor, K. D., Teumer, A., Thornton, T. A., Tranah, G. J., Wang, C., Wang, H., Warby, S. C., Andrew Wellman, D., Zee, P. C., Hanis, C. L., Laurie, C. C., Gottlieb, D. J., Patel, S. R., Zhu, X., Sunyaev, S. R., Saxena, R., Lin, X. & Redline, S., Mar 1 2018, In : American Journal of Respiratory Cell and Molecular Biology. 58, 3, p. 391-401 11 p.

Research output: Contribution to journalEditorial

Water recycling
Quantitative Trait Loci
Obstructive Sleep Apnea
Apnea
Meta-Analysis

Observational and Genetic Associations of Resting Heart Rate With Aortic Valve Calcium

Whelton, S. P., Mauer, A. C., Pencina, K. M., Massaro, J. M., D'Agostino, R. B., Fox, C. S., Hoffmann, U., Michos, E. D., Peloso, G. M., Dufresne, L., Engert, J. C., Kathiresan, S., Budoff, M., Post, W. S., Thanassoulis, G. & O'Donnell, C. J., Jan 1 2018, (Accepted/In press) In : American Journal of Cardiology.

Research output: Contribution to journalArticle

Aortic Valve
Heart Rate
Calcium
Cohort Studies
Atherosclerosis

Performance of glomerular filtration rate estimating equations in a community-based sample of Blacks and Whites: The multiethnic study of atherosclerosis

Inker, L. A., Levey, A. S., Tighiouart, H., Shafi, T., Eckfeldt, J. H., Johnson, C., Okparavero, A., Post, W. S., Coresh, J. & Shlipak, M. G., Mar 1 2018, In : Nephrology Dialysis Transplantation. 33, 3, p. 417-425 9 p.

Research output: Contribution to journalArticle

Cystatin C
Glomerular Filtration Rate
Creatinine
Atherosclerosis
Chronic Renal Insufficiency

Plasma tryptophan-kynurenine metabolites are altered in human immunodeficiency virus infection and associated with progression of carotid artery atherosclerosis

Qi, Q., Hua, S., Clish, C. B., Scott, J. M., Hanna, D. B., Wang, T., Haberlen, S. A., Shah, S. J., Glesby, M. J., Lazar, J. M., Burk, R. D., Hodis, H. N., Landay, A. L., Post, W. S., Anastos, K. & Kaplan, R. C., Jul 2 2018, In : Clinical Infectious Diseases. 67, 2, p. 235-242 8 p.

Research output: Contribution to journalArticle

Kynurenine
Carotid Artery Diseases
Kynurenic Acid
Virus Diseases
Carotid Arteries

Relation of Sex Hormone Levels with Prevalent and 10-Year Change in Aortic Distensibility Assessed by MRI: The Multi-Ethnic Study of Atherosclerosis

Subramanya, V., Ambale-Venkatesh, B., Ohyama, Y., Zhao, D., Nwabuo, C. C., Post, W. S., Guallar, E., Ouyang, P., Shah, S. J., Allison, M. A., Ndumele, C. E., Vaidya, D., Bluemke, D. A., Lima, J. A. & Michos, E. D., Jun 11 2018, In : American Journal of Hypertension. 31, 7, p. 774-783 10 p.

Research output: Contribution to journalArticle

Gonadal Steroid Hormones
Atherosclerosis
Testosterone
Estradiol
Magnetic Resonance Imaging

Resting heart rate and the incidence and progression of valvular calcium: The Multi-Ethnic Study of Atherosclerosis (MESA)

Amoakwa, K., Fashanu, O. E., Tibuakuu, M., Zhao, D., Guallar, E., Whelton, S. P., O'Neal, W. T., Post, W. S., Budoff, M. J. & Michos, E. D., Jun 1 2018, In : Atherosclerosis. 273, p. 45-52 8 p.

Research output: Contribution to journalArticle

Atherosclerosis
Heart Rate
Calcium
Incidence
Aortic Valve

Risk factors for progression of coronary artery calcification in patients with chronic kidney disease: The CRIC study

the CRIC Study Investigators, Apr 1 2018, In : Atherosclerosis. 271, p. 53-60 8 p.

Research output: Contribution to journalArticle

Chronic Renal Insufficiency
Coronary Vessels
Cohort Studies
Cardiovascular Diseases
Cystatin C

Sex hormone levels and change in left ventricular structure among men and post-menopausal women: The Multi-Ethnic Study of Atherosclerosis (MESA)

Subramanya, V., Zhao, D., Ouyang, P., Lima, J. A., Vaidya, D., Ndumele, C. E., Bluemke, D. A., Shah, S. J., Guallar, E., Nwabuo, C. C., Allison, M. A., Heckbert, S. R., Post, W. S. & Michos, E. D., Feb 1 2018, In : Maturitas. 108, p. 37-44 8 p.

Research output: Contribution to journalArticle

Gonadal Steroid Hormones
Sex Hormone-Binding Globulin
Atherosclerosis
Testosterone
Magnetic resonance

Ten-year association of coronary artery calcium with atherosclerotic cardiovascular disease (ASCVD) events: the multi-ethnic study of atherosclerosis (MESA)

Budoff, M. J., Young, R., Burke, G., Carr, J. J., Detrano, R. C., Folsom, A. R., Kronmal, R., Lima, J. A. C., Liu, K. J., McClelland, R. L., Michos, E., Post, W. S., Shea, S., Watson, K. E. & Wong, N. D., Jul 1 2018, In : European Heart Journal. 39, 25, p. 2401b-2408b

Research output: Contribution to journalArticle

Atherosclerosis
Coronary Vessels
Cardiovascular Diseases
Calcium
Coronary Disease

To T or not to T: Differences in Testosterone Use and Discontinuation by HIV Serostatus among Men who Have Sex with Men

Haberlen, S. A., Jacobson, L. P., Palella, F. J., Dobs, A., Plankey, M., Lake, J. E., Kingsley, L. A., Stall, R., Post, W. S. & Brown, T. T., Oct 1 2018, In : HIV Medicine. 19, 9, p. 634-644 11 p.

Research output: Contribution to journalArticle

Testosterone
HIV
Cardiovascular Diseases
Therapeutics
Los Angeles

Ultrasound carotid plaque features, cardiovascular disease risk factors and events: The Multi-Ethnic Study of Atherosclerosis

Mitchell, C., Korcarz, C. E., Gepner, A. D., Kaufman, J. D., Post, W., Tracy, R., Gassett, A. J., Ma, N., McClelland, R. L. & Stein, J. H., Jan 1 2018, (Accepted/In press) In : Atherosclerosis.

Research output: Contribution to journalArticle

Atherosclerosis
Cardiovascular Diseases
Coronary Disease
Coronary Vessels
Calcium
2017

Admixture Mapping of Subclinical Atherosclerosis and Subsequent Clinical Events among African Americans in 2 Large Cohort Studies

Shendre, A., Wiener, H., Irvin, M. R., Zhi, D., Limdi, N. A., Overton, E. T., Wassel, C. L., Divers, J., Rotter, J. I., Post, W. S. & Shrestha, S., Apr 1 2017, In : Circulation: Cardiovascular Genetics. 10, 2, e001569

Research output: Contribution to journalArticle

Carotid Intima-Media Thickness
Common Carotid Artery
African Americans
Atherosclerosis
Cohort Studies

Assessment of coronary artery calcium by chest CT compared with EKG-gated cardiac CT in the multicenter AIDS cohort study

Chandra, D., Gupta, A., Leader, J. K., Fitzpatrick, M., Kingsley, L. A., Kleerup, E., Haberlen, S. A., Budoff, M. J., Witt, M., Post, W. S., Sciurba, F. C. & Morris, A., Apr 1 2017, In : PLoS One. 12, 4, e0176557

Research output: Contribution to journalArticle

electrocardiography
coronary vessels
chest
cohort studies
Electrocardiography

Association between APOL1 genotypes and risk of cardiovascular disease in MESA (Multi-Ethnic Study of Atherosclerosis)

Chen, T. K., Katz, R., Estrella, M. M., Gutierrez, O. M., Kramer, H., Post, W. S., Shlipak, M. G., Wassel, C. L. & Peralta, C. A., Dec 1 2017, In : Journal of the American Heart Association. 6, 12, e007199

Research output: Contribution to journalArticle

Atherosclerosis
Cardiovascular Diseases
Genotype
Heart Failure
Confidence Intervals

Association of Cardiovascular Health With Subclinical Disease and Incident Events: The Multi-Ethnic Study of Atherosclerosis

Polonsky, T. S., Ning, H., Daviglus, M. L., Liu, K., Burke, G. L., Cushman, M., Eng, J., Folsom, A. R., Lutsey, P. L., Nettleton, J. A., Post, W. S., Sacco, R. L., Szklo, M. & Lloyd-Jones, D. M., Mar 1 2017, In : Journal of the American Heart Association. 6, 3, e004894

Research output: Contribution to journalArticle

Atherosclerosis
Health
Cardiovascular Diseases
Carotid Intima-Media Thickness
Coronary Vessels

Association of macrophage inflammation biomarkers with progression of subclinical carotid artery atherosclerosis in HIV-infected women and men

Hanna, D. B. , Lin, J. , Post, W. S. , Hodis, H. N. , Xue, X. , Anastos, K. , Cohen, M. H. , Gange, S. J. , Haberlen, S. A. , Heath, S. L. , Lazar, J. M. , Liu, C. , Mack, W. J. , Ofotokun, I. , Palella, F. J. , Tien, P. C. , Witt, M. D. , Landay, A. L. , Kingsley, L. A. , Tracy, R. P. & 1 others Kaplan, R. C., 2017, In : Journal of Infectious Diseases. 215, 9, p. 1352-1361 10 p.

Research output: Contribution to journalArticle

Carotid Artery Diseases
Carotid Arteries
Biomarkers
Macrophages
HIV

Association of Triglyceride-Related Genetic Variants With Mitral Annular Calcification

CHARGE Extracoronary Calcium Working Group, Jun 20 2017, In : Journal of the American College of Cardiology. 69, 24, p. 2941-2948 8 p.

Research output: Contribution to journalArticle

Triglycerides
Calcium
Atherosclerosis
Odds Ratio
Confidence Intervals

Associations of Coffee, Tea, and Caffeine Intake with Coronary Artery Calcification and Cardiovascular Events

Miller, P. E., Zhao, D., Frazier-Wood, A. C., Michos, E. D., Averill, M., Sandfort, V., Burke, G. L., Polak, J. F., Lima, J. A. C., Post, W. S., Blumenthal, R. S., Guallar, E. & Martin, S. S., Feb 1 2017, In : American Journal of Medicine. 130, 2, p. 188-197.e5

Research output: Contribution to journalArticle

Coffee
Tea
Caffeine
Coronary Vessels
Calcium

Blood monocyte transcriptome and epigenome analyses reveal loci associated with human atherosclerosis

Liu, Y. , Reynolds, L. M. , Ding, J. , Hou, L. , Lohman, K. , Young, T. , Cui, W. , Huang, Z. , Grenier, C. , Wan, M. , Stunnenberg, H. G. , Siscovick, D. , Hou, L. , Psaty, B. M. , Rich, S. S. , Rotter, J. I. , Kaufman, J. D. , Burke, G. L. , Murphy, S. , Jacobs, D. R. & 8 others Post, W., Hoeschele, I., Bell, D. A., Herrington, D., Parks, J. S., Tracy, R. P., McCall, C. E. & Stein, J. H., Dec 1 2017, In : Nature Communications. 8, 1, 393

Research output: Contribution to journalArticle

monocytes
arteriosclerosis
Methylation
Gene Expression Profiling
loci

Causal effect of plasminogen activator inhibitor type 1 on coronary heart disease

CHARGE Consortium Hemostatic Factor Working Group, ICBP Consortium & CHARGE Consortium Subclinical Working Group, Jun 1 2017, In : Journal of the American Heart Association. 6, 6, e004918

Research output: Contribution to journalArticle

Plasminogen Activator Inhibitor 1
Coronary Disease
Odds Ratio
Mendelian Randomization Analysis
Genome-Wide Association Study

Comparison of carotid plaque score and coronary artery calcium score for predicting cardiovascular disease events: The multi-ethnic study of atherosclerosis

Gepner, A. D., Young, R., Delaney, J. A., Budoff, M. J., Polak, J. F., Blaha, M. J., Post, W. S., Michos, E. D., Kaufman, J. & Stein, J. H., 2017, In : Journal of the American Heart Association. 6, 2, e005179

Research output: Contribution to journalArticle

Atherosclerosis
Coronary Vessels
Cardiovascular Diseases
Transient Ischemic Attack
Calcium

Density of calcium in the ascending thoracic aorta and risk of incident cardiovascular disease events

Thomas, I. C., McClelland, R. L., Michos, E. D., Allison, M. A., Forbang, N. I., Longstreth, W. T., Post, W. S., Wong, N. D., Budoff, M. J. & Criqui, M. H., Oct 1 2017, In : Atherosclerosis. 265, p. 190-196 7 p.

Research output: Contribution to journalArticle

Thoracic Aorta
Aorta
Cardiovascular Diseases
Calcium
Coronary Vessels

Evaluation of lipoprotein(a) electrophoretic and immunoassay methods in discriminating risk of calcific aortic valve disease and incident coronary heart disease: The multi-ethnic study of atherosclerosis

Cao, J., Steffen, B. T., Guan, W., Budoff, M., Michos, E. D., Kizer, J. R., Post, W. S. & Tsai, M. Y., Nov 1 2017, In : Clinical Chemistry. 63, 11, p. 1705-1713 9 p.

Research output: Contribution to journalArticle

Aortic Diseases
Lipoprotein(a)
Aortic Valve
Immunoassay
Coronary Disease

Fine mapping of QT interval regions in global populations refines previously identified QT interval loci and identifies signals unique to African and Hispanic descent populations

Avery, C. L. , Wassel, C. L. , Richard, M. A. , Highland, H. M. , Bien, S. , Zubair, N. , Soliman, E. Z. , Fornage, M. , Bielinski, S. J. , Tao, R. , Seyerle, A. A. , Shah, S. J. , Lloyd-Jones, D. M. , Buyske, S. , Rotter, J. I. , Post, W. S. , Rich, S. S. , Hindorff, L. A. , Jeff, J. M. , Shohet, R. V. & 8 others Sotoodehnia, N., Lin, D. Y., Whitsel, E. A., Peters, U., Haiman, C. A., Crawford, D. C., Kooperberg, C. & North, K. E., Apr 1 2017, In : Heart Rhythm. 14, 4, p. 572-580 9 p.

Research output: Contribution to journalArticle

Hispanic Americans
Single Nucleotide Polymorphism
Population
Genome-Wide Association Study
Biodiversity

Frailty and subclinical coronary atherosclerosis: The Multicenter AIDS Cohort Study (MACS)

Korada, S. K. C., Zhao, D., Tibuakuu, M., Brown, T. T., Jacobson, L. P., Guallar, E., Bolan, R. K., Palella, F. J., Margolick, J. B., Martinson, J. J., Budoff, M. J., Post, W. S. & Michos, E. D., 2017, (Accepted/In press) In : Atherosclerosis.

Research output: Contribution to journalArticle

Coronary Artery Disease
Acquired Immunodeficiency Syndrome
Cohort Studies
HIV
Coronary Vessels

Genetic associations with lipoprotein subfraction measures differ by ethnicity in the multi-ethnic study of atherosclerosis (MESA)

Wang, Z., Manichukal, A., Goff, D. C., Mora, S., Ordovas, J. M., Pajewski, N. M., Post, W. S., Rotter, J. I., Sale, M. M., Santorico, S. A., Siscovick, D., Tsai, M. Y., Arnett, D. K., Rich, S. & Frazier-Wood, A. C., Jun 1 2017, In : Human Genetics. 136, 6, p. 715-726 12 p.

Research output: Contribution to journalArticle

Lipoproteins
Atherosclerosis
Hispanic Americans
Genome
African Americans

HIV infection is associated with increased fatty infiltration of the thigh muscle with aging independent of fat distribution

Natsag, J., Erlandson, K. M., Sellmeyer, D. E., Haberlen, S. A., Margolick, J., Jacobson, L. P., Palella, F. J., Koletar, S. L., Lake, J. E., Post, W. S. & Brown, T. T., Jan 1 2017, In : PLoS One. 12, 1, e0169184

Research output: Contribution to journalArticle

HIV infections
thighs
Thigh
Infiltration
HIV Infections

Increased Risk of Myocardial Infarction in HIV-Infected Individuals in North America Compared with the General Population

Drozd, D. R. , Kitahata, M. M. , Althoff, K. N. , Zhang, J. , Gange, S. J. , Napravnik, S. , Burkholder, G. A. , Mathews, W. C. , Silverberg, M. J. , Sterling, T. R. , Heckbert, S. R. , Budoff, M. J. , Van Rompaey, S. , Delaney, J. A. C. , Wong, C. , Tong, W. , Palella, F. J. , Elion, R. A. , Martin, J. N. , Brooks, J. T. & 9 others Jacobson, L. P., Eron, J. J., Justice, A. C., Freiberg, M. S., Klein, D. B., Post, W. S., Saag, M. S., Moore, R. D. & Crane, H. M., Aug 15 2017, In : Journal of Acquired Immune Deficiency Syndromes. 75, 5, p. 568-576 9 p.

Research output: Contribution to journalArticle

North America
Myocardial Infarction
HIV
Incidence
Population

Lipoprotein(a) and Risk of Myocardial Infarction and Death in Chronic Kidney Disease: Findings From the CRIC Study (Chronic Renal Insufficiency Cohort)

Chronic Renal Insufficiency Cohort (CRIC) Study Investigators*, Oct 1 2017, In : Arteriosclerosis, Thrombosis, and Vascular Biology. 37, 10, p. 1971-1978 8 p.

Research output: Contribution to journalArticle

Lipoprotein(a)
Chronic Renal Insufficiency
Myocardial Infarction
Confidence Intervals
Proportional Hazards Models

PCSK9 Loss-of-Function Variants, Low-Density Lipoprotein Cholesterol, and Risk of Coronary Heart Disease and Stroke: Data from 9 Studies of Blacks and Whites

Kent, S. T. , Rosenson, R. S. , Avery, C. L. , Chen, Y. D. I. , Correa, A. , Cummings, S. R. , Cupples, L. A. , Cushman, M. , Evans, D. S. , Gudnason, V. , Harris, T. B. , Howard, G. , Irvin, M. R. , Judd, S. E. , Jukema, J. W. , Lange, L. , Levitan, E. B. , Li, X. , Liu, Y. , Post, W. S. & 15 others Postmus, I., Psaty, B. M., Rotter, J. I., Safford, M. M., Sitlani, C. M., Smith, A. V., Stewart, J. D., Trompet, S., Sun, F., Vasan, R. S., Woolley, J. M., Whitsel, E. A., Wiggins, K. L., Wilson, J. G. & Muntner, P., Aug 1 2017, In : Circulation: Cardiovascular Genetics. 10, 4, e001632

Research output: Contribution to journalArticle

LDL Cholesterol
Coronary Disease
Stroke
Confidence Intervals
Odds Ratio

Pulmonary vascular volume, impaired left ventricular filling and dyspnea: The MESA Lung Study

Aaron, C. P. , Hoffman, E. A. , Lima, J. A. C. , Kawut, S. M. , Bertoni, A. G. , Vogel-Claussen, J. , Habibi, M. , Hueper, K. , Jacobs, D. R. , Kalhan, R. , Michos, E. D. , Post, W. S. , Prince, M. R. , Smith, B. M. , Ambale-Venkatesh, B. , Liu, C. Y. , Zemrak, F. , Watson, K. E. , Budoff, M. , Bluemke, D. A. & 1 others Barr, R. G., Apr 1 2017, In : PLoS One. 12, 4, e0176180

Research output: Contribution to journalArticle

dyspnea
blood vessels
Dyspnea
Blood Vessels
Magnetic resonance

Relation of Diastolic Blood Pressure and Coronary Artery Calcium to Coronary Events and Outcomes (From the Multi-Ethnic Study of Atherosclerosis)

Rahman, F., Al Rifai, M., Blaha, M. J., Nasir, K., Budoff, M. J., Psaty, B. M., Post, W. S., Blumenthal, R. S. & McEvoy, J. W., 2017, (Accepted/In press) In : American Journal of Cardiology.

Research output: Contribution to journalArticle

Atherosclerosis
Coronary Vessels
Blood Pressure
Calcium
Coronary Disease

Serum vitamin D and sex hormones levels in men and women: The Multi-Ethnic Study of Atherosclerosis (MESA)

Zhao, D., Ouyang, P., de Boer, I. H., Lutsey, P. L., Farag, Y. M. K., Guallar, E., Siscovick, D. S., Post, W. S., Kalyani, R. R., Billups, K. L. & Michos, E. D., Feb 1 2017, In : Maturitas. 96, p. 95-102 8 p.

Research output: Contribution to journalArticle

Gonadal Steroid Hormones
Vitamin D
Testosterone
Atherosclerosis
Sex Hormone-Binding Globulin

The impact of long-term moderate and heavy alcohol consumption on incident atherosclerosis among persons living with HIV

Kelso-Chichetto, N. E., Plankey, M., Sheps, D. S., Abraham, A. G., Chen, X., Shoptaw, S., Kaplan, R. C., Post, W. S. & Cook, R. L., Dec 1 2017, In : Drug and Alcohol Dependence. 181, p. 235-241 7 p.

Research output: Contribution to journalArticle

Alcohol Drinking
Atherosclerosis
Alcohols
HIV
Cohort Studies

The metabolic syndrome and risk of sudden cardiac death: The atherosclerosis risk in communities study

Hess, P. L., Al-Khalidi, H. R., Friedman, D. J., Mulder, H., Kucharska-Newton, A., Rosamond, W. R., Lopes, R. D., Gersh, B. J., Mark, D. B., Curtis, L. H., Post, W. S., Prineas, R. J., Sotoodehnia, N. & Al-Khatib, S. M., Aug 1 2017, In : Journal of the American Heart Association. 6, 8, e006103

Research output: Contribution to journalArticle

Sudden Cardiac Death
Atherosclerosis
Confidence Intervals
HDL Lipoproteins
LDL Lipoproteins

Validity of Cardiovascular Data From Electronic Sources: The Multi-Ethnic Study of Atherosclerosis and HealthLNK

Ahmad, F. S., Chan, C., Rosenman, M. B., Post, W. S., Fort, D. G., Greenland, P., Liu, K. J., Kho, A. N. & Allen, N. B., Jul 12 2017, (Accepted/In press) In : Circulation.

Research output: Contribution to journalArticle

Atherosclerosis
International Classification of Diseases
Blood Pressure
Research
Heart Failure
2016
Hepatitis Viruses
Virus Diseases
Chronic Hepatitis
Hepacivirus
Coronary Artery Disease

Anatomic fat depots and coronary plaque among human immunodeficiency virus-infected and uninfected men in the Multicenter AIDS Cohort Study

Palella, F. J., McKibben, R., Post, W. S., Li, X., Budoff, M., Kingsley, L., Witt, M. D., Jacobson, L. P. & Brown, T. T., Apr 1 2016, In : Open Forum Infectious Diseases. 3, 2, ofw098

Research output: Contribution to journalArticle

Acquired Immunodeficiency Syndrome
Cohort Studies
Fats
HIV
Intra-Abdominal Fat