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2018

Hepatitis e virus seroprevalence and correlates of anti-HEV IgG antibodies in the Rakai District, Uganda

the Rakai Health Sciences Program Mar 1 2018 In : Journal of Infectious Diseases. 217, 5, p. 785-789 5 p.

Research output: Contribution to journalArticle

Hepatitis E virus
Hepatitis Viruses
Uganda
Seroepidemiologic Studies
Immunoglobulin G
2017

Comparison of cross-sectional HIV incidence assay results from dried blood spots and plasma

Schlusser, K. E., Pilcher, C., Kallas, E. G., Santos, B. R., Deeks, S. G., Facente, S., Keating, S. M., Busch, M. P., Murphy, G., Welte, A., Quinn, T., Eshleman, S. H. & Laeyendecker, O. Feb 1 2017 In : PLoS ONE. 12, 2, e0172283

Research output: Contribution to journalArticle

Assays
Blood
HIV
Plasmas
incidence

Contrasting antibody responses to intrasubtype superinfection with CRF02-AG

Courtney, C. R., Mayr, L., Nanfack, A. J., Banin, A. N., Tuen, M., Pan, R., Jiang, X., Kong, X. P., Kirkpatrick, A. R., Bruno, D., Martens, C. A., Sykora, L., Porcella, S. F., Redd, A. D., Quinn, T. C., Nyambi, P. N. & Dürr, R. Mar 1 2017 In : PLoS ONE. 12, 3, e0173705

Research output: Contribution to journalArticle

Superinfection
Neutralizing Antibodies
Antibody Formation
antibodies
Antibodies

Elevated cytomegalovirus IgG antibody levels are associated with HIV-1 disease progression and immune activation

Patel, E. U., Gianella, S., Newell, K., Tobian, A. A. R., Kirkpatrick, A. R., Nalugoda, F., Grabowski, M. K., Gray, R. H., Serwadda, D., Quinn, T. C., Redd, A. D. & Reynolds, S. J. Jan 24 2017 (Accepted/In press) In : AIDS.

Research output: Contribution to journalArticle

Cytomegalovirus
Disease Progression
HIV-1
Immunoglobulin G
Antibodies

Erratum: Precision of the Kalon Herpes Simplex Virus Type 2 IgG ELISA: An international inter-laboratory assessment [BMC Infect Dis. 15, (2015)(398)] DOI: 10.1186/s12879-015-1130-6

Patel, E. U., Manucci, J., Kahle, E. M., Lingappa, J. R., Morrow, R. A., Piwowar-Manning, E., James, A., Maluzi, K. F., Cheeba, M. M., Gray, G., Kosloff, B., Delany-Moretlwe, S., Inambao, M., Vwalika, B., Quinn, T. C. & Laeyendecker, O. May 19 2017 In : BMC Infectious Diseases. 17, 1, 355

Research output: Contribution to journalComment/debate

Human Herpesvirus 2
Immunoglobulin G
Enzyme-Linked Immunosorbent Assay
Tropical Medicine
Zambia

Finding youths at risk for HIV infection: Targeted Testing, universal testing, or both?

Agwu, A. L. & Quinn, T. C. Jun 1 2017 In : JAMA Pediatrics. 171, 6, p. 517-518 2 p.

Research output: Contribution to journalEditorial

HIV Infections
Uganda
Randomized Controlled Trials
HIV
Health
Therapeutics

Low rates of transmitted drug resistance among newly identified HIV-1 seroconverters in Rural Rakai, Uganda

Reynolds, S. J., Ssempijja, V., Galiwango, R., Ndyanabo, A., Nakigozi, G., Lyagoba, F., Nazziwa, J., Redd, A., Lamers, S. L., Gray, R., Wawer, M., Serwadda, D. & Quinn, T. C. May 1 2017 In : AIDS Research and Human Retroviruses. 33, 5, p. 448-451 4 p.

Research output: Contribution to journalArticle

Uganda
Drug Resistance
HIV-1
Mutation
Reverse Transcriptase Inhibitors
Chlamydia trachomatis
Inflammation
Trachoma
Infection
Chlamydia Infections

Reduced frequency of cells latently infected with replication-competent human immunodeficiency virus-1 in virally suppressed individuals living in Rakai, Uganda

Prodger, J. L., Lai, J., Reynolds, S. J., Keruly, J. C., Moore, R. D., Kasule, J., Kityamuweesi, T., Buule, P., Serwadda, D., Nason, M., Capoferri, A. A., Porcella, S. F., Siliciano, R. F., Redd, A. D., Siliciano, J. D. & Quinn, T. C. Oct 1 2017 In : Clinical Infectious Diseases. 65, 8, p. 1308-1315 8 p.

Research output: Contribution to journalArticle

Uganda
HIV-1
T-Lymphocytes
Baltimore
Virus Diseases
Hepacivirus
India
HIV
Pharmaceutical Preparations
Costs and Cost Analysis
HIV Antigens
Superinfection
Art
Viral Load
Immunoenzyme Techniques

Short Communication: False Recent Ratio of the Limiting-Antigen Avidity Assay and Viral Load Testing Algorithm among Cameroonians with Long-Term HIV Infection

Lynch, B. A., Patel, E. U., Courtney, C. R., Nanfack, A. J., Bimela, J., Wang, X., Eid, I., Quinn, T. C., Laeyendecker, O., Nyambi, P. N., Duerr, R. & Redd, A. D. Nov 1 2017 In : AIDS Research and Human Retroviruses. 33, 11, p. 1114-1116 3 p.

Research output: Contribution to journalArticle

Viral Load
HIV Infections
HIV
Central Africa
Antigens

Treating village newcomers and travelers for trachoma: Results from ASANTE cluster randomized trial

West, S. K., Munoz, B., Mkocha, H., Dize, L., Gaydos, C. A., Swenor, B., Ervin, A. M. & Quinn, T. C. Jun 1 2017 In : PLoS ONE. 12, 6, e0178595

Research output: Contribution to journalArticle

Trachoma
villages
infection
Infection
monitoring
Uganda
Heterosexuality
HIV
Genotype
Male Circumcision

Weak HIV Antibody Responses in Perinatally-Infected Young Adults

Kirkpatrick, A. R., Unsal, A. B., Blankson, J. N., Moore, R. D., Quinn, T. C., Hadigan, C. & Laeyendecker, O. Jun 23 2017 (Accepted/In press) In : Pediatric Infectious Disease Journal.

Research output: Contribution to journalArticle

HIV Antibodies
Antibody Formation
Young Adult
HIV
Incidence
2016

Association of medical male circumcision and antiretroviral therapyscale-up with community HIV incidence in Rakai, Uganda

Kong, X., Kigozi, G., Ssekasanvu, J., Nalugoda, F., Nakigozi, G., Ndyanabo, A., Lutalo, T., Reynolds, S. J., Ssekubugu, R., Kagaayi, J., Bugos, E., Chang, L. W., Nanlesta, P., Mary, G., Berman, A., Quinn, T. C., Serwadda, D., Wawer, M. J. & Gray, R. H. Jul 12 2016 In : JAMA - Journal of the American Medical Association. 316, 2, p. 182-190 9 p.

Research output: Contribution to journalArticle

Male Circumcision
Uganda
HIV
Incidence
Therapeutics

A transmission-virulence evolutionary trade-off explains attenuation of HIV-1 in uganda

Blanquart, F., Grabowski, M. K., Herbeck, J., Nalugoda, F., Serwadda, D., Eller, M. A., Robb, M. L., Gray, R., Kigozi, G., Laeyendecker, O., Lythgoe, K. A., Nakigozi, G., Quinn, T. C., Reynolds, S. J., Wawer, M. J. & Fraser, C. Nov 5 2016 In : eLife. 5, NOVEMBER2016, e20492

Research output: Contribution to journalArticle

Uganda
Virulence
HIV-1
Pathogens
Viral Load
Trachoma
Chlamydia trachomatis
Antibodies
Surveys and Questionnaires

Detection of acute and early HIV-1 infections in an HIV hyper-endemic area with limited resources

Mayaphi, S. H., Martin, D. J., Quinn, T. C., Laeyendecker, O., Olorunju, S. A. S., Tintinger, G. R. & Stoltz, A. C. Oct 1 2016 In : PLoS One. 11, 10, e0164943

Research output: Contribution to journalArticle

HIV infections
Human immunodeficiency virus 1
HIV Infections
HIV-1
HIV
Immunoenzyme Techniques
HIV
Incidence
Population
Infection

Evaluation of hidden HIV infections in an urban ED with a rapid HIV screening program

Hsieh, Y. H., Kelen, G. D., Beck, K. J., Kraus, C. K., Shahan, J. B., Laeyendecker, O. B., Quinn, T. C. & Rothman, R. E. Feb 1 2016 In : American Journal of Emergency Medicine. 34, 2, p. 180-184 5 p.

Research output: Contribution to journalArticle

HIV Infections
Hospital Emergency Service
HIV
Serum
Self Report
Centers for Disease Control and Prevention (U.S.)
Hepacivirus
Hospital Emergency Service
Virus Diseases
Parturition

Heterogeneity of the HIV epidemic in agrarian, trading, and fishing communities in Rakai, Uganda: an observational epidemiological study

Chang, L. W., Grabowski, M. K., Ssekubugu, R., Nalugoda, F., Kigozi, G., Nantume, B., Lessler, J., Moore, S. M., Quinn, T. C., Reynolds, S. J., Gray, R. H., Serwadda, D. & Wawer, M. J. Aug 1 2016 In : The Lancet HIV. 3, 8, p. e388-e396

Research output: Contribution to journalArticle

Uganda
Observational Studies
Epidemiologic Studies
HIV
National Institute of Allergy and Infectious Diseases (U.S.)

Immunological signaling during herpes simplex virus-2 and cytomegalovirus vaginal shedding after initiation of antiretroviral treatment

Nason, M. C., Patel, E. U., Kirkpatrick, A. R., Prodger, J. L., Shahabi, K., Tobian, A. A. R., Gianella, S., Kalibbala, S., Ssebbowa, P., Kaul, R., Gray, R. H., Quinn, T. C., Serwadda, D., Reynolds, S. J. & Redd, A. D. Apr 1 2016 In : Open Forum Infectious Diseases. 3, 2, ofw073

Research output: Contribution to journalComment/debate

Human Herpesvirus 2
Cytomegalovirus
Interleukin-6
Virus Shedding
Cytokines

Improvements in the continuum of HIV care in an inner-city emergency department

Kelen, G. D., Hsieh, Y. H., Rothman, R. E., Patel, E. U., Laeyendecker, O. B., Marzinke, M. A., Clarke, W., Parsons, T., Manucci, J. L. & Quinn, T. C. Jan 2 2016 In : AIDS. 30, 1, p. 113-120 8 p.

Research output: Contribution to journalArticle

Continuity of Patient Care
Hospital Emergency Service
HIV
Hospital Departments
Baltimore

Longitudinal household surveillance for malaria in Rakai, Uganda

Newell, K., Kiggundu, V., Ouma, J., Baghendage, E., Kiwanuka, N., Gray, R., Serwadda, D., Hobbs, C. V., Healy, S. A., Quinn, T. C. & Reynolds, S. J. Feb 9 2016 In : Malaria Journal. 15, 1, 1128

Research output: Contribution to journalArticle

Uganda
Malaria
Parasitemia
Caregivers
HIV
Human Herpesvirus 2
antineoplaston A10
Virus Diseases
Hepacivirus
Hospital Emergency Service

Partner Human Papillomavirus Viral Load and Incident Human Papillomavirus Detection in Heterosexual Couples

Grabowski, M. K., Kong, X., Gray, R. H., Serwadda, D., Kigozi, G., Gravitt, P. E., Nalugoda, F., Reynolds, S. J., Wawer, M. J., Redd, A. D., Watya, S., Quinn, T. C. & Tobian, A. A. R. Mar 15 2016 In : Journal of Infectious Diseases. 213, 6, p. 948-956 9 p.

Research output: Contribution to journalArticle

Heterosexuality
Viral Load
Genotype
Confidence Intervals
Male Circumcision
Azithromycin
Trachoma
Chlamydia trachomatis
Inflammation
Chlamydia Infections

Treatment as Prevention: Characterization of partner infections in the HIV Prevention Trials Network 052 trial

Eshleman, S. H. , Hudelson, S. E. , Redd, A. D. , Swanstrom, R. , Ou, S. S. , Zhang, X. C. , Ping, L. H. , Piwowar-Manning, E. , Porcella, S. F. , Sievers, M. F. , Martens, C. A. , Bruno, D. , Dukhovlinova, E. , McCauley, M. , Gamble, T. , Fogel, J. M. , Sabin, D. , Quinn, T. C. , Gunde, L. , Maliwichi, M. & 13 others Nhando, N., Akelo, V., Moyo, S., Panchia, R., Kumarasamy, N., Chotirosniramit, N., Gonçalves de Melo, M., Pilotto, J., Grinsztejn, B., Mayer, K., Chen, Y. Q., Hughes, J. P. & Cohen, M. S. Aug 16 2016 (Accepted/In press) In : Journal of Acquired Immune Deficiency Syndromes.

Research output: Contribution to journalArticle

HIV Infections
Infection
HIV
Therapeutics
Genetic Linkage
Antibody Affinity
Virus Diseases
Hepacivirus
Immunoglobulin G
Biomarkers

Using nearly full-genome HIV sequence data improves phylogeny reconstruction in a simulated epidemic

Yebra, G. , Hodcroft, E. B. , Ragonnet-Cronin, M. L. , Pillay, D. , Leigh Brown, A. J. , Fraser, C. , Kellam, P. , De Oliveira, T. , Dennis, A. , Hoppe, A. , Kityo, C. , Frampton, D. , Ssemwanga, D. , Tanser, F. , Keshani, J. , Lingappa, J. , Herbeck, J. , Wawer, M. , Essex, M. , Cohen, M. S. & 14 others Paton, N., Ratmann, O., Kaleebu, P., Hayes, R., Fidler, S., Quinn, T., Novitsky, V., Haywards, A., Nastouli, E., Morris, S., Clark, D., Kozlakidis, Z., PANGEA-HIV Consortium & ICONIC Project Dec 23 2016 In : Scientific Reports. 6, 39489

Research output: Contribution to journalArticle

Phylogeny
HIV
Genome
pol Genes
gag Genes
2015

Antibody maturation in women who acquire HIV infection while using antiretroviral preexposure prophylaxis

Laeyendecker, O., Redd, A. D., Nason, M., Longosz, A. F., Karim, Q. A., Naranbhai, V., Garrett, N., Eshleman, S. H., Abdool Karim, S. S. & Quinn, T. C. 2015 In : Journal of Infectious Diseases. 212, 5, p. 754-759 6 p.

Research output: Contribution to journalArticle

Tenofovir
Virus Diseases
HIV
Antibodies
Antibody Affinity

Burden of hepatitis C virus disease and access to hepatitis C virus services in people who inject drugs in India: A cross-sectional study

Solomon, S. S., Mehta, S. H., Srikrishnan, A. K., Solomon, S., McFall, A. M., Laeyendecker, O., Celentano, D. D., Iqbal, S. H., Anand, S., Vasudevan, C. K., Saravanan, S., Lucas, G. M., Kumar, M. S., Sulkowski, M. S. & Quinn, T. C. Jan 1 2015 In : Lancet Infectious Diseases. 15, 1, p. 36-45 10 p.

Research output: Contribution to journalArticle

Virus Diseases
Hepacivirus
India
Cross-Sectional Studies
Pharmaceutical Preparations

Comparison of antibody responses to HIV infection in ugandan women infected with HIV subtypes A and D

Longosz, A. F., Morrison, C. S., Chen, P. L., Brand, H. H., Arts, E., Nankya, I., Salata, R. A., Quinn, T. C., Eshleman, S. H. & Laeyendecker, O. Apr 1 2015 In : AIDS Research and Human Retroviruses. 31, 4, p. 421-427 7 p.

Research output: Contribution to journalArticle

HIV Infections
Antibody Formation
HIV
Infection
Antigens

Decreased monocyte activation with daily acyclovir use in HIV-1/HSV-2 coinfected women

Redd, A. D., Newell, K., Patel, E. U., Nalugoda, F., Ssebbowa, P., Kalibbala, S., Frank, M. A., Tobian, A. A. R., Gray, R. H., Quinn, T. C., Serwadda, D. & Reynolds, S. J. Nov 1 2015 In : Sexually Transmitted Infections. 91, 7, p. 485-488 4 p.

Research output: Contribution to journalArticle

Human Herpesvirus 2
Acyclovir
HIV-1
Monocytes
Viral Load

Differential associations of IL-6 and intestinal fatty acid-binding protein with progressive untreated HIV-1 infection in Rakai, Uganda

Olwenyi, O. A., Naluyima, P., Cham, F., Quinn, T. C., Serwadda, D., Sewankambo, N. K., Gray, R. H., Sandberg, J. K., Michael, N. L., Wabwire-Mangen, F., Robb, M. L. & Eller, M. A. Dec 1 2015 (Accepted/In press) In : Journal of Acquired Immune Deficiency Syndromes.

Research output: Contribution to journalArticle

Fatty Acid-Binding Proteins
Uganda
HIV Infections
HIV-1
Interleukin-6

Durable suppression of HIV-1 after virologic monitoring-based antiretroviral adherence counseling in rakai, Uganda

Billioux, A., Nakigozi, G., Newell, K., Chang, L. W., Quinn, T. C., Gray, R. H., Ndyanabo, A., Galiwango, R., Kiggundu, V., Serwadda, D. & Reynolds, S. J. May 1 2015 In : PLoS One. 10, 5, e0127235

Research output: Contribution to journalArticle

Uganda
counseling
viral load
Human immunodeficiency virus 1
Viral Load
Preventive Medicine
Uganda
Sulfamethoxazole Drug Combination Trimethoprim
HIV
House Calls

Evaluation of postpartum HIV superinfection and mother-to-child transmission

Redd, A. D., Wendel, S. K. J., Longosz, A. F., Fogel, J. M., Dadabhai, S., Kumwenda, N., Sun, J., Walker, M. P., Bruno, D., Martens, C., Eshleman, S. H., Porcella, S. F., Quinn, T. C. & Tahac, T. E. Jul 31 2015 In : AIDS. 29, 12, p. 1567-1573 7 p.

Research output: Contribution to journalArticle

Superinfection
Postpartum Period
Mothers
HIV
Post-Exposure Prophylaxis

Genome sequencing and analysis of geographically diverse clinical isolates of herpes simplex virus 2

Newman, R. M., Lamers, S. L., Weiner, B., Ray, S. C., Colgrove, R. C., Diaz, F., Jing, L., Wang, K., Saif, S., Young, S., Henn, M., Laeyendecker, O., Tobian, A. A. R., Cohen, J. I., Koelle, D. M., Quinn, T. C. & Knipe, D. M. 2015 In : Journal of Virology. 89, 16, p. 8219-8232 14 p.

Research output: Contribution to journalArticle

Human herpesvirus 2
Human Herpesvirus 2
Genome
genome
Human Herpesvirus 1

Global diversity within and between human herpesvirus 1 and 2 glycoproteins

Lamers, S. L., Newman, R. M., Laeyendecker, O., Tobian, A. A. R., Colgrove, R. C., Ray, S. C., Koelle, D. M., Cohen, J., Knipe, D. M. & Quinn, T. C. 2015 In : Journal of Virology. 89, 16, p. 8206-8218 13 p.

Research output: Contribution to journalArticle

Human herpesvirus 2
Human herpesvirus 1
Human Herpesvirus 2
Human Herpesvirus 1
glycoproteins

Herpes Simples Virus Type 2 Shedding from Male Circumcision Wounds in Rakai, Uganda

Grabowski, M. K., Kigozi, G., Gray, R. H., Armour, B., Manucci, J., Serwadda, D., Redd, A. D., Nalugoda, F., Patel, E. U., Wawer, M. J., Quinn, T. C. & Tobian, A. A. R. 2015 In : Journal of Infectious Diseases. 212, 10, p. 1613-1617 5 p.

Research output: Contribution to journalArticle

Male Circumcision
Human Herpesvirus 2
Uganda
Virus Shedding
Viruses
Continuity of Patient Care
Hospital Emergency Service
HIV
Self Report
HIV Seroprevalence

HIV Shedding from Male Circumcision Wounds in HIV-Infected Men: A Prospective Cohort Study

Tobian, A. A. R., Kigozi, G., Manucci, J., Grabowski, M. K., Serwadda, D., Musoke, R., Redd, A. D., Nalugoda, F., Reynolds, S. J., Kighoma, N., Laeyendecker, O., Lessler, J., Gray, R. H., Quinn, T. C. & Wawer, M. J. Apr 1 2015 In : PLoS Medicine. 12, 4, e1001820

Research output: Contribution to journalArticle

Male Circumcision
Cohort Studies
HIV
Prospective Studies
Wounds and Injuries

HIV type 1 disease progression to AIDS and death in a rural ugandan cohort is primarily dependent on viral load despite variable subtype and T-cell immune activation levels

Eller, M. A., Opollo, M. S., Liu, M., Redd, A. D., Eller, L. A., Kityo, C., Kayiwa, J., Laeyendecker, O., Wawer, M. J., Milazzo, M., Kiwanuka, N., Gray, R. H., Serwadda, D., Sewankambo, N. K., Quinn, T. C., Michael, N. L., Wabwire-Mangen, F., Sandberg, J. K. & Robb, M. L. May 15 2015 In : Journal of Infectious Diseases. 211, 10, p. 1574-1584 11 p.

Research output: Contribution to journalArticle

Viral Load
Disease Progression
HIV-1
Acquired Immunodeficiency Syndrome
T-Lymphocytes

Hypertension, cardiovascular risk factors and antihypertensive medication utilisation among HIV-infected individuals in Rakai, Uganda

Sander, L. D., Newell, K., Ssebbowa, P., Serwadda, D., Quinn, T. C., Gray, R. H., Wawer, M. J., Mondo, G. & Reynolds, S. Mar 1 2015 In : Tropical Medicine and International Health. 20, 3, p. 391-396 6 p.

Research output: Contribution to journalArticle

Uganda
Antihypertensive Agents
HIV
Hypertension
Blood Pressure

Interferon lambda 4 genotype is not associated with recurrence of oral or genital herpes

Kuhs, K. A. L., Kuniholm, M. H., Pfeiffer, R. M., Chen, S., Desai, S., Edlin, B. R., Peters, M. G., Plankey, M., Sharp, G. B., Strickler, H. D., Villacres, M. C., Quinn, T. C., Gange, S. J., Prokunina-Olsson, L., Greenblatt, R. M. & O'Brien, T. R. Oct 2 2015 In : PLoS One. 10, 10, e0138827

Research output: Contribution to journalArticle

Human herpesvirus 2
Herpes Genitalis
Human Herpesvirus 2
interferons
Viruses