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2018

Concurrent BRAF/MEK inhibitors in BRAF V600-Mutant high-grade primary brain tumors

Schreck, K. C., Guajardo, A., Lin, D. D. M., Eberhart, C. G. & Grossman, S. A. Apr 1 2018 In : JNCCN Journal of the National Comprehensive Cancer Network. 16, 4, p. 343-347 5 p.

Research output: Contribution to journalComment/debate

Mitogen-Activated Protein Kinase Kinases
Brain Neoplasms
temozolomide
Mutation
Therapeutics

Identifying corneal infections in formalin-fixed specimens using next generation sequencing

Li, Z., Breitwieser, F. P., Lu, J., Jun, A. S., Asnaghi, L., Salzberg, S. L. & Eberhart, C. G. Jan 1 2018 In : Investigative Ophthalmology and Visual Science. 59, 1, p. 280-288 9 p.

Research output: Contribution to journalArticle

Acanthamoeba
Metagenomics
Keratitis
Cytomegalovirus
Formaldehyde
Central Nervous System Neoplasms
Insulinoma
Brain
Proteins
Staining and Labeling

Opposing Effects of CREBBP Mutations Govern the Phenotype of Rubinstein-Taybi Syndrome and Adult SHH Medulloblastoma

Merk, D. J. , Ohli, J. , Merk, N. D. , Thatikonda, V. , Morrissy, S. , Schoof, M. , Schmid, S. N. , Harrison, L. , Filser, S. , Ahlfeld, J. , Erkek, S. , Raithatha, K. , Andreska, T. , Weißhaar, M. , Launspach, M. , Neumann, J. E. , Shakarami, M. , Plenker, D. , Marra, M. A. , Li, Y. & 18 others Mungall, A. J., Moore, R. A., Ma, Y., Jones, S. J. M., Lutz, B., Ertl-Wagner, B., Rossi, A., Wagener, R., Siebert, R., Jung, A., Eberhart, C. G., Lach, B., Sendtner, M., Pfister, S. M., Taylor, M. D., Chavez, L., Kool, M. & Schüller, U. Mar 26 2018 In : Developmental Cell. 44, 6, p. 709-724.e6

Research output: Contribution to journalArticle

Rubinstein-Taybi Syndrome
Medulloblastoma
Acetyltransferases
Cerebellum
Phenotype
Eye Diseases
Lacrimal Apparatus
Immunoglobulin G
Orbit
Eye Manifestations
Retinal Pigment Epithelium
Venules
Membranes
Vitis
Macular Degeneration

PD-L1 expression in medulloblastoma: An evaluation by subgroup

Martin, A. M. , Nirschl, C. J. , Polanczyk, M. J. , Bell, W. R. , Nirschl, T. R. , Harris-Bookman, S. , Phallen, J. , Hicks, J. , Martinez, D. , Ogurtsova, A. , Xu, H. , Sullivan, L. M. , Meeker, A. K. , Raabe, E. H. , Cohen, K. J. , Eberhart, C. G. , Burger, P. C. , Santi, M. , Taube, J. M. , Pardoll, D. M. & 2 others Drake, C. G. & Lim, M. Apr 10 2018 In : Oncotarget. 9, 27, p. 19177-19191 15 p.

Research output: Contribution to journalArticle

Medulloblastoma
Biomarkers
Cell Line
Tumor Microenvironment
Gamma Rays

Primary mesenchymal chondrosarcoma of the orbit: Histopathological report of 3 pediatric cases

Alkatan, H. M., Eberhart, C. G., Alshomar, K. M., Elkhamary, S. M. & Maktabi, A. M. Y. Jan 1 2018 (Accepted/In press) In : Saudi Journal of Ophthalmology.

Research output: Contribution to journalArticle

Mesenchymal Chondrosarcoma
Orbit
Pediatrics
Exophthalmos
Skeleton

Ribavirin as a potential therapeutic for atypical teratoid/rhabdoid tumors

Casaos, J. , Huq, S. , Lott, T. , Felder, R. , Choi, J. , Gorelick, N. , Peters, M. , Xia, Y. , Maxwell, R. , Zhao, T. , Ji, C. , Simon, T. , Sesen, J. , Scotland, S. J. , Kast, R. E. , Rubens, J. , Raabe, E. , Eberhart, C. G. , Jackson, E. M. , Brem, H. & 2 others Tyler, B. & Skuli, N. Jan 1 2018 In : Oncotarget. 9, 8, p. 8054-8067 14 p.

Research output: Contribution to journalArticle

Ribavirin
Brain Neoplasms
Glioma
Therapeutics
Growth
2017
Glioblastoma
Cytomegalovirus
Glioma
In Situ Hybridization
Real-Time Polymerase Chain Reaction
Image-Guided Biopsy
Amides
Glioma
Protons
Magnetic Resonance Spectroscopy

A mouse model of MYCN-driven retinoblastoma reveals MYCN-independent tumor reemergence

Wu, N., Jia, D., Bates, B., Basom, R., Eberhart, C. G. & MacPherson, D. Mar 1 2017 In : Journal of Clinical Investigation. 127, 3, p. 888-898 11 p.

Research output: Contribution to journalArticle

Retinoblastoma
Neoplasms
Anaplasia
Gene Amplification
Tumor Suppressor Genes

An immunocompetent mouse model of human glioblastoma

Semenkow, S., Li, S., Kahlert, U. D., Raabe, E. H., Xu, J., Arnold, A., Janowski, M., Oh, B. C., Brandacher, G., Bulte, J. W. M., Eberhart, C. G. & Walczak, P. Sep 1 2017 In : Oncotarget. 8, 37, p. 61072-61082 11 p.

Research output: Contribution to journalArticle

Glioblastoma
Neoplasms
Precision Medicine
Heterologous Transplantation
Adaptive Immunity

Delayed Superficial Migration of Retained Hyaluronic Acid Years Following Periocular Injection

Chang, J. R., Baharestani, S., Salek, S. S., Piluek, W. J., Eberhart, C. G. & McCulley, T. J. May 1 2017 In : Ophthalmic Plastic and Reconstructive Surgery. 33, 3S, p. S116-S118

Research output: Contribution to journalArticle

Intraocular Injections
Hyaluronic Acid
Injections
Hyaluronoglucosaminidase
Cosmetics

Discriminating MGMT promoter methylation status in patients with glioblastoma employing amide proton transfer-weighted MRI metrics

Jiang, S., Rui, Q., Wang, Y., Heo, H. Y., Zou, T., Yu, H., Zhang, Y., Wang, X., Du, Y., Wen, X., Chen, F., Wang, J., Eberhart, C. G., Zhou, J. & Wen, Z. Dec 12 2017 (Accepted/In press) In : European Radiology. p. 1-9 9 p.

Research output: Contribution to journalArticle

Methyltransferases
Glioblastoma
Amides
Methylation
Protons

HIF-1α- Targeting Acriflavine Provides Long Term Survival and Radiological Tumor Response in Brain Cancer Therapy

Mangraviti, A. , Raghavan, T. , Volpin, F. , Skuli, N. , Gullotti, D. , Zhou, J. , Asnaghi, L. , Sankey, E. , Liu, A. , Wang, Y. , Lee, D. H. , Gorelick, N. , Serra, R. , Peters, M. , Schriefer, D. , Delaspre, F. , Rodriguez, F. J. , Eberhart, C. G. , Brem, H. , Olivi, A. & 1 others Tyler, B. Dec 1 2017 In : Scientific Reports. 7, 1, 14978

Research output: Contribution to journalArticle

Acriflavine
Brain Neoplasms
Survival
Neoplasms
Glioma

Hypoxia inhibits growth, proliferation, and increases response to chemotherapy in retinoblastoma cells

Yang, Q., Tripathy, A., Yu, W., Eberhart, C. G. & Asnaghi, L. Sep 1 2017 In : Experimental Eye Research. 162, p. 48-61 14 p.

Research output: Contribution to journalArticle

Retinoblastoma
Drug Therapy
Growth
Glycolysis
Protein-Lysine 6-Oxidase

Inhibition of soluble epoxide hydrolase prevents diabetic retinopathy

Hu, J. , Dziumbla, S. , Lin, J. , Bibli, S. I. , Zukunft, S. , De Mos, J. , Awwad, K. , Frömel, T. , Jungmann, A. , Devraj, K. , Cheng, Z. , Wang, L. , Fauser, S. , Eberhart, C. G. , Sodhi, A. , Hammock, B. D. , Liebner, S. , Müller, O. J. , Glaubitz, C. , Hammes, H. P. & 2 others Popp, R. & Fleming, I. Dec 14 2017 In : Nature. 552, 7684, p. 248-252 5 p.

Research output: Contribution to journalArticle

Epoxide Hydrolases
Diabetic Retinopathy
Pericytes
Blood Vessels
Retina

Intertumoral Heterogeneity within Medulloblastoma Subgroups

Cavalli, F. M. G. , Remke, M. , Rampasek, L. , Peacock, J. , Shih, D. J. H. , Luu, B. , Garzia, L. , Torchia, J. , Nor, C. , Morrissy, A. S. , Agnihotri, S. , Thompson, Y. Y. , Kuzan-Fischer, C. M. , Farooq, H. , Isaev, K. , Daniels, C. , Cho, B. K. , Kim, S. K. , Wang, K. C. , Lee, J. Y. & 30 others Grajkowska, W. A., Perek-Polnik, M., Vasiljevic, A., Faure-Conter, C., Jouvet, A., Giannini, C., Nageswara Rao, A. A., Li, K. K. W., Ng, H. K., Eberhart, C. G., Pollack, I. F., Hamilton, R. L., Gillespie, G. Y., Olson, J. M., Leary, S., Weiss, W. A., Lach, B., Chambless, L. B., Thompson, R. C., Cooper, M. K., Vibhakar, R., Hauser, P., van Veelen, M. L. C., Kros, J. M., French, P. J., Ra, Y. S., Kumabe, T., López-Aguilar, E., Zitterbart, K. & Robinson, S. Jun 12 2017 In : Cancer Cell. 31, 6, p. 737-754.e6

Research output: Contribution to journalArticle

Medulloblastoma
DNA Methylation
Cluster Analysis
Clinical Trials
Genome

Melanoma subtypes demonstrate distinct PD-L1 expression profiles

Kaunitz, G. J., Cottrell, T. R., Lilo, M., Muthappan, V., Esandrio, J., Berry, S., Xu, H., Ogurtsova, A., Anders, R. A., Fischer, A. H., Kraft, S., Gerstenblith, M. R., Thompson, C. L., Honda, K., Cuda, J. D., Eberhart, C. G., Handa, J. T., Lipson, E. J. & Taube, J. M. Sep 1 2017 In : Laboratory Investigation. 97, 9, p. 1063-1071 9 p.

Research output: Contribution to journalArticle

Melanoma
Solar System
Tumor-Infiltrating Lymphocytes
Tumor Microenvironment
Extremities

mTORC1-Mediated Inhibition of 4EBP1 Is Essential for Hedgehog Signaling-Driven Translation and Medulloblastoma

Wu, C. C., Hou, S., Orr, B. A., Kuo, B. R., Youn, Y. H., Ong, T., Roth, F., Eberhart, C. G., Robinson, G. W., Solecki, D. J., Taketo, M. M., Gilbertson, R. J., Roussel, M. F. & Han, Y. G. Dec 18 2017 In : Developmental Cell. 43, 6, p. 673-688.e5

Research output: Contribution to journalArticle

Medulloblastoma
Hedgehogs
Sirolimus
Growth and Development
Cerebellum

Predicting IDH mutation status in grade II gliomas using amide proton transfer-weighted (APTw) MRI

Jiang, S., Zou, T., Eberhart, C. G., Villalobos, M. A. V., Heo, H. Y., Zhang, Y., Wang, Y., Wang, X., Yu, H., Du, Y., van Zijl, P. C. M., Wen, Z. & Zhou, J. Sep 1 2017 In : Magnetic Resonance in Medicine. 78, 3, p. 1100-1109 10 p.

Research output: Contribution to journalArticle

Isocitrate Dehydrogenase
Amides
Glioma
Protons
Mutation

Rabbit model of human gliomas: Implications for intra-arterial drug delivery

Qin, H., Janowski, M., Pearl, M. S., Malysz-Cymborska, I., Li, S., Eberhart, C. G. & Walczak, P. Jan 1 2017 In : PLoS ONE. 12, 1, e0169656

Research output: Contribution to journalArticle

Drug delivery
Glioma
Tumors
rabbits
Rabbits

Strategies to enhance the distribution of nanotherapeutics in the brain

Zhang, C., Mastorakos, P., Sobral, M., Berry, S., Song, E., Nance, E., Eberhart, C. G., Hanes, J. & Suk, J. S. 2017 (Accepted/In press) In : Journal of Controlled Release.

Research output: Contribution to journalArticle

Nanoparticles
Convection
Brain
Blood-Brain Barrier
Extracellular Matrix

The dual mTOR kinase inhibitor TAK228 inhibits tumorigenicity and enhances radiosensitization in diffuse intrinsic pontine glioma

Miyahara, H., Yadavilli, S., Natsumeda, M., Rubens, J. A., Rodgers, L., Kambhampati, M., Taylor, I. C., Kaur, H., Asnaghi, L., Eberhart, C. G., Warren, K. E., Nazarian, J. & Raabe, E. H. Aug 1 2017 In : Cancer Letters. 400, p. 110-116 7 p.

Research output: Contribution to journalArticle

Glioma
Phosphotransferases
Brain Stem Neoplasms
Apoptosis
S 6

The TORC1/2 inhibitor TAK228 sensitizes atypical teratoid rhabdoid tumors to cisplatin-induced cytotoxicity

Rubens, J. A., Wang, S. Z., Price, A., Weingart, M. F., Allen, S. J., Orr, B. A., Eberhart, C. G. & Raabe, E. H. Oct 1 2017 In : Neuro-Oncology. 19, 10, p. 1361-1371 11 p.

Research output: Contribution to journalArticle

Cisplatin
Sirolimus
Heterografts
Apoptosis
Neoplasms
2016

Alterations in cellular metabolome after pharmacological inhibition of Notch in glioblastoma cells

Kahlert, U. D., Cheng, M., Koch, K., Marchionni, L., Fan, X., Raabe, E. H., Maciaczyk, J., Glunde, K. & Eberhart, C. G. Mar 1 2016 In : International Journal of Cancer. 138, 5, p. 1246-1255 10 p.

Research output: Contribution to journalArticle

Metabolome
Glioblastoma
Glutamic Acid
Pharmacology
Glutaminase

Altered gene expression in conjunctival squamous cell carcinoma

Mahale, A., Alkatan, H., Alwadani, S., Othman, M., Suarez, M. J., Price, A., Al-Hussain, H., Jastaneiah, S., Yu, W., Maktabi, A., Deepak, E. P., Eberhart, C. G. & Asnaghi, L. Feb 26 2016 (Accepted/In press) In : Modern Pathology.

Research output: Contribution to journalArticle

Matrix Metalloproteinases
Squamous Cell Carcinoma
Clusterin
Gene Expression
Carcinoma in Situ

Convection enhanced delivery of cisplatin-loaded brain penetrating nanoparticles cures malignant glioma in rats

Zhang, C., Nance, E. A., Mastorakos, P., Chisholm, J., Berry, S., Eberhart, C., Tyler, B., Brem, H., Suk, J. S. & Hanes, J. Dec 5 2016 (Accepted/In press) In : Journal of Controlled Release.

Research output: Contribution to journalArticle

Convection
Glioma
Nanoparticles
Cisplatin
Brain

Divergent clonal selection dominates medulloblastoma at recurrence

Morrissy, A. S. , Garzia, L. , Shih, D. J. H. , Zuyderduyn, S. , Huang, X. , Skowron, P. , Remke, M. , Cavalli, F. M. G. , Ramaswamy, V. , Lindsay, P. E. , Jelveh, S. , Donovan, L. K. , Wang, X. , Luu, B. , Zayne, K. , Li, Y. , Mayoh, C. , Thiessen, N. , Mercier, E. , Mungall, K. L. & 118 others Ma, Y., Tse, K., Zeng, T., Shumansky, K., Roth, A. J. L., Shah, S., Farooq, H., Kijima, N., Holgado, B. L., Lee, J. J. Y., Matan-Lithwick, S., Liu, J., Mack, S. C., Manno, A., Michealraj, K. A., Nor, C., Peacock, J., Qin, L., Reimand, J., Rolider, A., Thompson, Y. Y., Wu, X., Pugh, T., Ally, A., Bilenky, M., Butterfield, Y. S. N., Carlsen, R., Cheng, Y., Chuah, E., Corbett, R. D., Dhalla, N., He, A., Lee, D., Li, H. I., Long, W., Mayo, M., Plettner, P., Qian, J. Q., Schein, J. E., Tam, A., Wong, T., Birol, I., Zhao, Y., Faria, C. C., Pimentel, J., Nunes, S., Shalaby, T., Grotzer, M., Pollack, I. F., Hamilton, R. L., Li, X. N., Bendel, A. E., Fults, D. W., Walter, A. W., Kumabe, T., Tominaga, T., Collins, V. P., Cho, Y. J., Hoffman, C., Lyden, D., Wisoff, J. H., Garvin, J. H., Stearns, D. S., Massimi, L., Schüller, U., Sterba, J., Zitterbart, K., Puget, S., Ayrault, O., Dunn, S. E., Tirapelli, D. P. C., Carlotti, C. G., Wheeler, H., Hallahan, A. R., Ingram, W., MacDonald, T. J., Olson, J. J., Van Meir, E. G., Lee, J. Y., Wang, K. C., Kim, S. K., Cho, B. K., Pietsch, T., Fleischhack, G., Tippelt, S., Ra, Y. S., Bailey, S., Lindsey, J. C., Clifford, S. C., Eberhart, C. G., Cooper, M. K., Packer, R. J., Massimino, M., Garre, M. L., Bartels, U., Tabori, U., Hawkins, C. E., Dirks, P., Bouffet, E., Rutka, J. T., Wechsler-Reya, R. J., Weiss, W. A., Collier, L. S., Dupuy, A. J., Korshunov, A., Jones, D. T. W., Kool, M., Northcott, P. A., Pfister, S. M., Largaespada, D. A., Mungall, A. J., Moore, R. A., Jabado, N., Bader, G. D., Jones, S. J. M., Malkin, D., Marra, M. A. & Taylor, M. D. Jan 21 2016 In : Nature. 529, 7586, p. 351-357 7 p.

Research output: Contribution to journalArticle

Medulloblastoma
Recurrence
Image-Guided Radiotherapy
Neoplasms
Therapeutics

Establishment and biological characterization of a panel of glioblastoma multiforme (GBM) and GBM variant oncosphere cell lines

Binder, Z. A., Wilson, K. M., Salmasi, V., Orr, B. A., Eberhart, C. G., Siu, I. M., Lim, M., Weingart, J. D., Quinones-Hinojosa, A., Bettegowda, C., Kassam, A. B., Olivi, A., Brem, H., Riggins, G. J. & Gallia, G. L. Mar 1 2016 In : PLoS One. 11, 3, e0150271

Research output: Contribution to journalArticle

oncospheres
Glioblastoma
Tumors
Cells
cell lines

Hypoxia-inducible factor 1 upregulation of both VEGF and ANGPTL4 is required to promote the angiogenic phenotype in uveal melanoma

Hu, K., Babapoor-Farrokhran, S., Rodrigues, M., Deshpande, M., Puchner, B., Kashiwabuchi, F., Hassan, S. J., Asnaghi, L., Handa, J. T., Merbs, S., Eberhart, C. G., Semenza, G. L., Montaner, S. & Sodhi, A. 2016 In : Oncotarget. 7, 7, p. 7816-7828 13 p.

Research output: Contribution to journalArticle

Hypoxia-Inducible Factor 1
Vascular Endothelial Growth Factor A
Up-Regulation
Phenotype
Uveal melanoma

Multiple cilia suppress tumour formation

Eberhart, C. Mar 30 2016 In : Nature Cell Biology. 18, 4, p. 368-369 2 p.

Research output: Contribution to journalShort survey

Notch1 Receptor
Choroid Plexus Neoplasms
Hedgehog Proteins
Cilia
Cell Proliferation

MYB-QKI rearrangements in angiocentric glioma drive tumorigenicity through a tripartite mechanism

Bandopadhayay, P. , Ramkissoon, L. A. , Jain, P. , Bergthold, G. , Wala, J. , Zeid, R. , Schumacher, S. E. , Urbanski, L. , O'Rourke, R. , Gibson, W. J. , Pelton, K. , Ramkissoon, S. H. , Han, H. J. , Zhu, Y. , Choudhari, N. , Silva, A. , Boucher, K. , Henn, R. E. , Kang, Y. J. , Knoff, D. & 42 others Paolella, B. R., Gladden-Young, A., Varlet, P., Pages, M., Horowitz, P. M., Federation, A., Malkin, H., Tracy, A. A., Seepo, S., Ducar, M., Van Hummelen, P., Santi, M., Buccoliero, A. M., Scagnet, M., Bowers, D. C., Giannini, C., Puget, S., Hawkins, C., Tabori, U., Klekner, A., Bognar, L., Burger, P. C., Eberhart, C., Rodriguez, F. J., Hill, D. A., Mueller, S., Haas-Kogan, D. A., Phillips, J. J., Santagata, S., Stiles, C. D., Bradner, J. E., Jabado, N., Goren, A., Grill, J., Ligon, A. H., Goumnerova, L., Waanders, A. J., Storm, P. B., Kieran, M. W., Ligon, K. L., Beroukhim, R. & Resnick, A. C. Mar 1 2016 In : Nature Genetics. 48, 3, p. 273-282 10 p.

Research output: Contribution to journalArticle

Glioma
Pediatrics
Epigenomics
Neoplasms
Carcinogenesis

Somatic cell transfer of c-Myc and Bcl-2 induces large-cell anaplastic medulloblastomas in mice

Jenkins, N. C., Rao, G., Eberhart, C. G., Pedone, C. A., Dubuc, A. M. & Fults, D. W. Feb 1 2016 In : Journal of Neuro-Oncology. 126, 3, p. 415-424 10 p.

Research output: Contribution to journalArticle

Medulloblastoma
Neoplasms
Brain Neoplasms
Stem Cells
Nestin

Somatic mutations of DICER1 and KMT2D are frequent in intraocular medulloepitheliomas

Sahm, F., Jakobiec, F. A., Meyer, J., Schrimpf, D., Eberhart, C. G., Hovestadt, V., Capper, D., Lambo, S., Ryzhova, M., Schüller, U., Zheludkova, O., Kumirova, E., Lichter, P., von Deimling, A., Jones, D. T. W., Pfister, S. M., Kool, M. & Korshunov, A. 2016 (Accepted/In press) In : Genes Chromosomes and Cancer.

Research output: Contribution to journalArticle

Primitive Neuroectodermal Tumors
Mutation
Neoplasms
Neuroepithelial Neoplasms
Genome

Subepidermal Calcified Nodules of the Eyelid Differ in Children and Adults

AlWadani, S., Suarez, M. J., Kass, J. J., MacQuaid, E., Edward, D. P., Alkatan, H. & Eberhart, C. Jul 29 2016 (Accepted/In press) In : Ophthalmic Plastic and Reconstructive Surgery.

Research output: Contribution to journalArticle

Eyelids
Foreign-Body Reaction
Inflammation
Calcinosis
Gout

Targeting Notch Signaling and Autophagy Increases Cytotoxicity in Glioblastoma Neurospheres

Natsumeda, M., Maitani, K., Liu, Y., Miyahara, H., Kaur, H., Chu, Q., Zhang, H., D. Kahlert, U. & Eberhart, C. G. Nov 1 2016 In : Brain Pathology. 26, 6, p. 713-723 11 p.

Research output: Contribution to journalArticle

Autophagy
Glioblastoma
Glioma
Stem Cells
Amyloid Precursor Protein Secretases

Targeting Notch signaling as a novel therapy for retinoblastoma

Asnaghi, L., Tripathy, A., Yang, Q., Kaur, H., Hanaford, A., Yu, W. & Eberhart, C. G. 2016 In : Oncotarget. 7, 43, p. 70028-70044 17 p.

Research output: Contribution to journalArticle

Retinoblastoma
Therapeutics
Small Interfering RNA
Down-Regulation
Amyloid Precursor Protein Secretases

Therapeutic impact of cytoreductive surgery and irradiation of posterior fossa ependymoma in the molecular era: A retrospective multicohort analysis

Ramaswamy, V. , Hielscher, T. , Mack, S. C. , Lassaletta, A. , Lin, T. , Pajtler, K. W. , Jones, D. T. W. , Luu, B. , Cavalli, F. M. G. , Aldape, K. , Remke, M. , Mynarek, M. , Rutkowski, S. , Gururangan, S. , McLendon, R. E. , Lipp, E. S. , Dunham, C. , Hukin, J. , Eisenstat, D. D. , Fulton, D. & 95 others Van Landeghem, F. K. H., Santi, M., Van Veelen, M. L. C., Van Meir, E. G., Osuka, S., Fan, X., Muraszko, K. M., Tirapelli, D. P. C., Oba-Shinjo, S. M., Marie, S. K. N., Carlotti, C. G., Lee, J. Y., Rao, A. A. N., Giannini, C., Faria, C. C., Nunes, S., Mora, J., Hamilton, R. L., Hauser, P., Jabado, N., Petrecca, K., Jung, S., Massimi, L., Zollo, M., Cinalli, G., Bognár, L., Klekner, A., Hortobágyi, T., Leary, S., Ermoian, R. P., Olson, J. M., Leonard, J. R., Gardner, C., Grajkowska, W. A., Chambless, L. B., Cain, J., Eberhart, C. G., Ahsan, S., Massimino, M., Giangaspero, F., Buttarelli, F. R., Packer, R. J., Emery, L., Yong, W. H., Soto, H., Liau, L. M., Everson, R., Grossbach, A., Shalaby, T., Grotzer, M., Karajannis, M. A., Zagzag, D., Wheeler, H., Von Hoff, K., Alonso, M. M., Tuñon, T., Schüller, U., Zitterbart, K., Sterba, J., Chan, J. A., Guzman, M., Elbabaa, S. K., Colman, H., Dhall, G., Fisher, P. G., Fouladi, M., Gajjar, A., Goldman, S., Hwang, E., Kool, M., Ladha, H., Vera-Bolanos, E., Wani, K., Lieberman, F., Mikkelsen, T., Omuro, A. M., Pollack, I. F., Prados, M., Robins, H. I., Soffietti, R., Wu, J., Metellus, P., Tabori, U., Bartels, U., Bouffet, E., Hawkins, C. E., Rutka, J. T., Dirks, P., Pfister, S. M., Merchant, T. E., Gilbert, M. R., Armstrong, T. S., Korshunov, A., Ellison, D. W. & Taylor, M. D. Jul 20 2016 In : Journal of Clinical Oncology. 34, 21, p. 2468-2477 10 p.

Research output: Contribution to journalArticle

Ependymoma
Radiotherapy
Biomarkers
Radiation
Therapeutics

The transcriptional modulator HMGA2 promotes stemness and tumorigenicity in glioblastoma

Kaur, H., Ali, S. Z., Huey, L., Hütt-Cabezas, M., Taylor, I., Mao, X. G., Weingart, M., Chu, Q., Rodriguez, F. J., Eberhart, C. G. & Raabe, E. H. Jul 10 2016 In : Cancer Letters. 377, 1, p. 55-64 10 p.

Research output: Contribution to journalArticle

AT-Hook Motifs
Glioblastoma
Stem Cell Factor
Neoplastic Stem Cells
Tumor Cell Line
2015

Analysis of varicella-zoster virus in temporal arteries biopsy positive and negative for giant cell arteritis

Nagel, M. A. , White, T. , Khmeleva, N. , Rempel, A. , Boyer, P. J. , Bennett, J. L. , Haller, A. , Lear-Kaul, K. , Kandasmy, B. , Amato, M. , Wood, E. , Durairaj, V. , Fogt, F. , Tamhankar, M. A. , Grossniklaus, H. E. , Poppiti, R. J. , Bockelman, B. , Keyvani, K. , Pollak, L. , Mendlovic, S. & 7 others Fowkes, M., Eberhart, C. G., Buttmann, M., Toyka, K. V., Meyer-Ter-Vehn, T., Petursdottir, V. & Gilden, D. Nov 1 2015 In : JAMA Neurology. 72, 11, p. 1281-1287 7 p.

Research output: Contribution to journalArticle

Temporal Arteries
Giant Cell Arteritis
Human Herpesvirus 3
Biopsy
Antigens

Clinicopathologic implications of NF1 gene alterations in diffuse gliomas

Vizcaíno, M. A., Shah, S., Eberhart, C. G. & Rodriguez, F. J. Sep 1 2015 In : Human Pathology. 46, 9, p. 1323-1330 8 p.

Research output: Contribution to journalArticle

Glioblastoma
Glioma
Genes
Atlases
Fluorescence In Situ Hybridization

Comparative integrated molecular analysis of intraocular medulloepitheliomas and central nervous system embryonal tumors with multilayered rosettes confirms that they are distinct nosologic entities

Korshunov, A., Jakobiec, F. A., Eberhart, C. G., Hovestadt, V., Capper, D., Jones, D. T. W., Sturm, D., Stagner, A. M., Edward, D. P., Eagle, R. C., Proia, A. D., Koch, A., Ryzhova, M., Ektova, A., Schüller, U., Zheludkova, O., Lichter, P., von Deimling, A., Pfister, S. M. & Kool, M. Dec 1 2015 In : Neuropathology. 35, 6, p. 538-544 7 p.

Research output: Contribution to journalArticle

Primitive Neuroectodermal Tumors
Central Nervous System Neoplasms
Neoplasms
Eye Neoplasms
Epigenomics

Corticosteroid-loaded biodegradable nanoparticles for prevention of corneal allograft rejection in rats

Pan, Q., Xu, Q., Boylan, N. J., Lamb, N. W., Emmert, D. G., Yang, J. C., Tang, L., Heflin, T., Alwadani, S., Eberhart, C. G., Stark, W. J. & Hanes, J. Mar 10 2015 In : Journal of Controlled Release. 201, p. 32-40 9 p.

Research output: Contribution to journalArticle

dexamethasone 21-phosphate
Graft Rejection
Nanoparticles
Allografts
Adrenal Cortex Hormones

Differential DNA methylation identified in the blood and retina of AMD patients

Oliver, V. F., Jaffe, A. E., Song, J., Wang, G., Zhang, P., Branham, K. E., Swaroop, A., Eberhart, C. G., Zack, D. J., Qian, J. & Merbs, S. L. Jan 1 2015 In : Epigenetics. 10, 8, p. 698-707 10 p.

Research output: Contribution to journalArticle

Macular Degeneration
DNA Methylation
Retina
Epigenomics
Methylation

Disrupting LIN28 in atypical teratoid rhabdoid tumors reveals the importance of the mitogen activated protein kinase pathway as a therapeutic target

Weingart, M. F., Roth, J. J., Hutt-Cabezas, M., Busse, T. M., Kaur, H., Price, A., Maynard, R., Rubens, J., Taylor, I., Mao, X. G., Xu, J., Kuwahara, Y., Allen, S. J., Erdreich-Epstein, A., Weissman, B. E., Orr, B. A., Eberhart, C. G., Biegel, J. A. & Raabe, E. H. 2015 In : Oncotarget. 6, 5, p. 3165-3177 13 p.

Research output: Contribution to journalArticle

Mitogen-Activated Protein Kinases
Tumor Cell Line
MicroRNAs
Therapeutics
Pediatrics

Disrupting NOTCH Slows Diffuse Intrinsic Pontine Glioma Growth, Enhances Radiation Sensitivity, and Shows Combinatorial Efficacy With Bromodomain Inhibition

Taylor, I. C., Hütt-Cabezas, M., Brandt, W. D., Kambhampati, M., Nazarian, J., Chang, H. T., Warren, K. E., Eberhart, C. G. & Raabe, E. H. Aug 31 2015 In : Journal of Neuropathology and Experimental Neurology. 74, 8, p. 778-790 13 p.

Research output: Contribution to journalArticle

Radiation Tolerance
Glioma
Growth
Amyloid Precursor Protein Secretases
Radiotherapy

DNMT-dependent suppression of microRNA regulates the induction of GBM tumor-propagating phenotype by Oct4 and Sox2

Lopez-Bertoni, H., Lal, B., Li, A., Caplan, M., Guerrero-Cázares, H., Eberhart, C. G., Quiñones-Hinojosa, A., Glas, M., Scheffler, B., Laterra, J. & Li, Y. Jul 23 2015 In : Oncogene. 34, 30, p. 3994-4004 11 p.

Research output: Contribution to journalArticle

Transferases
MicroRNAs
Phenotype
DNA
Neoplasms

EMT-associated factors promote invasive properties of uveal melanoma cells

Asnaghi, L., Gezgin, G., Tripathy, A., Handa, J. T., Merbs, S. L., van der Velden, P. A., Jager, M. J., Harbour, J. W. & Eberhart, C. G. Aug 25 2015 In : Molecular Vision. 21, p. 919-929 11 p.

Research output: Contribution to journalArticle

Epithelial-Mesenchymal Transition
Down-Regulation
Neoplasms
Growth
Messenger RNA