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2018

Association of macular and peripheral retinal macro-pseudocysts with chronic retinal detachment

Alvin Liu, T. Y., Adelita Vizcaino, M., Eberhart, C. G. & Sachdeva, M. M., Aug 1 2018, In : JAMA Ophthalmology. 136, 8, p. 956-958 3 p.

Research output: Contribution to journalLetter

Retinal Detachment

ATRX loss induces multiple hallmarks of the alternative lengthening of telomeres (ALT) phenotype in human glioma cell lines in a cell line-specific manner

Brosnan-Cashman, J. A., Yuan, M., Graham, M. K., Rizzo, A. J., Myers, K. M., Davis, C., Zhang, R., Esopi, D. M., Raabe, E. H., Eberhart, C. G., Heaphy, C. M. & Meeker, A. K., Sep 1 2018, In : PloS one. 13, 9, e0204159

Research output: Contribution to journalArticle

Telomere Homeostasis
telomeres
Glioma
cell lines
Phenotype

Bioreducible Polymeric Nanoparticles Containing Multiplexed Cancer Stem Cell Regulating miRNAs Inhibit Glioblastoma Growth and Prolong Survival

Lopez-Bertoni, H., Kozielski, K. L., Rui, Y., Lal, B., Vaughan, H., Wilson, D. R., Mihelson, N., Eberhart, C. G., Laterra, J. & Green, J. J., Jul 11 2018, In : Nano Letters. 18, 7, p. 4086-4094 9 p.

Research output: Contribution to journalArticle

stem cells
Stem cells
Tumors
delivery
cancer

Concurrent BRAF/MEK inhibitors in BRAF V600-Mutant high-grade primary brain tumors

Schreck, K. C., Guajardo, A., Lin, D. D. M., Eberhart, C. G. & Grossman, S. A., Apr 1 2018, In : JNCCN Journal of the National Comprehensive Cancer Network. 16, 4, p. 343-347 5 p.

Research output: Contribution to journalComment/debate

Mitogen-Activated Protein Kinase Kinases
Brain Neoplasms
temozolomide
Mutation
Therapeutics

Development and optimization of metagenomic next-generation sequencing methods for cerebrospinal fluid diagnostics

Simner, P. J., Miller, H. B., Breitwieser, F. P., Monsalve, G. P., Pardo, C. A., Salzberg, S. L., Sears, C. L., Thomas, D. L., Eberhart, C. G. & Carrolla, K. C., Sep 1 2018, In : Journal of clinical microbiology. 56, 9, e00472

Research output: Contribution to journalArticle

Metagenomics
Cerebrospinal Fluid
Standard of Care
DNA Sequence Analysis
Genome

Endocrine mucin-producing sweat gland carcinoma: A study of 11 cases with molecular analysis

Qin, H., Moore, R. F., Ho, C. Y., Eshleman, J., Eberhart, C. G. & Cuda, J., Sep 1 2018, In : Journal of Cutaneous Pathology. 45, 9, p. 681-687 7 p.

Research output: Contribution to journalArticle

Sweat Glands
Mucins
Mucinous Adenocarcinoma
Carcinoma
Keratin-20

Identifying corneal infections in formalin-fixed specimens using next generation sequencing

Li, Z., Breitwieser, F. P., Lu, J., Jun, A. S., Asnaghi, L., Salzberg, S. L. & Eberhart, C. G., Jan 1 2018, In : Investigative Ophthalmology and Visual Science. 59, 1, p. 280-288 9 p.

Research output: Contribution to journalArticle

Acanthamoeba
Metagenomics
Keratitis
Cytomegalovirus
Formaldehyde
Central Nervous System Neoplasms
Insulinoma
Brain
Proteins
Staining and Labeling

MicroRNA (miR) 125b regulates cell growth and invasion in pediatric low grade glioma

Yuan, M., Da Silva, A. C. A. L., Arnold, A., Okeke, L., Ames, H., Correa-Cerro, L. S., Vizcaino, M. A., Ho, C. Y., Eberhart, C. G. & Rodriguez, F. J., Dec 1 2018, In : Scientific Reports. 8, 1, 12506

Research output: Contribution to journalArticle

MicroRNAs
Glioma
Astrocytoma
Pediatrics
Growth

Opposing Effects of CREBBP Mutations Govern the Phenotype of Rubinstein-Taybi Syndrome and Adult SHH Medulloblastoma

Merk, D. J. , Ohli, J. , Merk, N. D. , Thatikonda, V. , Morrissy, S. , Schoof, M. , Schmid, S. N. , Harrison, L. , Filser, S. , Ahlfeld, J. , Erkek, S. , Raithatha, K. , Andreska, T. , Weißhaar, M. , Launspach, M. , Neumann, J. E. , Shakarami, M. , Plenker, D. , Marra, M. A. , Li, Y. & 18 others Mungall, A. J., Moore, R. A., Ma, Y., Jones, S. J. M., Lutz, B., Ertl-Wagner, B., Rossi, A., Wagener, R., Siebert, R., Jung, A., Eberhart, C. G., Lach, B., Sendtner, M., Pfister, S. M., Taylor, M. D., Chavez, L., Kool, M. & Schüller, U., Mar 26 2018, In : Developmental Cell. 44, 6, p. 709-724.e6

Research output: Contribution to journalArticle

Rubinstein-Taybi Syndrome
Medulloblastoma
Acetyltransferases
Cerebellum
Phenotype
Eye Diseases
Lacrimal Apparatus
Immunoglobulin G
Orbit
Eye Manifestations
Retinal Pigment Epithelium
Venules
Membranes
Vitis
Macular Degeneration

PD-L1 expression in medulloblastoma: An evaluation by subgroup

Martin, A. M. , Nirschl, C. J. , Polanczyk, M. J. , Bell, W. R. , Nirschl, T. R. , Harris-Bookman, S. , Phallen, J. , Hicks, J. , Martinez, D. , Ogurtsova, A. , Xu, H. , Sullivan, L. M. , Meeker, A. K. , Raabe, E. H. , Cohen, K. J. , Eberhart, C. G. , Burger, P. C. , Santi, M. , Taube, J. M. , Pardoll, D. M. & 2 others Drake, C. G. & Lim, M., Apr 10 2018, In : Oncotarget. 9, 27, p. 19177-19191 15 p.

Research output: Contribution to journalArticle

Medulloblastoma
Biomarkers
Cell Line
Tumor Microenvironment
Gamma Rays

Primary mesenchymal chondrosarcoma of the orbit: Histopathological report of 3 pediatric cases

Alkatan, H. M., Eberhart, C. G., Alshomar, K. M., Elkhamary, S. M. & Maktabi, A. M. Y., Jan 1 2018, (Accepted/In press) In : Saudi Journal of Ophthalmology.

Research output: Contribution to journalArticle

Mesenchymal Chondrosarcoma
Orbit
Pediatrics
Exophthalmos
Skeleton

Ribavirin as a potential therapeutic for atypical teratoid/rhabdoid tumors

Casaos, J. , Huq, S. , Lott, T. , Felder, R. , Choi, J. , Gorelick, N. , Peters, M. , Xia, Y. , Maxwell, R. , Zhao, T. , Ji, C. , Simon, T. , Sesen, J. , Scotland, S. J. , Kast, R. E. , Rubens, J. , Raabe, E. , Eberhart, C. G. , Jackson, E. M. , Brem, H. & 2 others Tyler, B. & Skuli, N., Jan 1 2018, In : Oncotarget. 9, 8, p. 8054-8067 14 p.

Research output: Contribution to journalArticle

Ribavirin
Brain Neoplasms
Glioma
Therapeutics
Growth
2017
Glioblastoma
Cytomegalovirus
Glioma
In Situ Hybridization
Real-Time Polymerase Chain Reaction
Image-Guided Biopsy
Amides
Glioma
Protons
Magnetic Resonance Spectroscopy

A mouse model of MYCN-driven retinoblastoma reveals MYCN-independent tumor reemergence

Wu, N., Jia, D., Bates, B., Basom, R., Eberhart, C. G. & MacPherson, D., Mar 1 2017, In : Journal of Clinical Investigation. 127, 3, p. 888-898 11 p.

Research output: Contribution to journalArticle

Retinoblastoma
Neoplasms
Anaplasia
Gene Amplification
Tumor Suppressor Genes

An immunocompetent mouse model of human glioblastoma

Semenkow, S., Li, S., Kahlert, U. D., Raabe, E. H., Xu, J., Arnold, A., Janowski, M., Oh, B. C., Brandacher, G., Bulte, J. W. M., Eberhart, C. G. & Walczak, P., Sep 1 2017, In : Oncotarget. 8, 37, p. 61072-61082 11 p.

Research output: Contribution to journalArticle

Glioblastoma
Neoplasms
Precision Medicine
Heterologous Transplantation
Adaptive Immunity

Delayed Superficial Migration of Retained Hyaluronic Acid Years Following Periocular Injection

Chang, J. R., Baharestani, S., Salek, S. S., Piluek, W. J., Eberhart, C. G. & McCulley, T. J., May 1 2017, In : Ophthalmic Plastic and Reconstructive Surgery. 33, 3S, p. S116-S118

Research output: Contribution to journalArticle

Intraocular Injections
Hyaluronic Acid
Injections
Hyaluronoglucosaminidase
Cosmetics

Discriminating MGMT promoter methylation status in patients with glioblastoma employing amide proton transfer-weighted MRI metrics

Jiang, S., Rui, Q., Wang, Y., Heo, H. Y., Zou, T., Yu, H., Zhang, Y., Wang, X., Du, Y., Wen, X., Chen, F., Wang, J., Eberhart, C. G., Zhou, J. & Wen, Z., Dec 12 2017, (Accepted/In press) In : European Radiology. p. 1-9 9 p.

Research output: Contribution to journalArticle

Methyltransferases
Glioblastoma
Amides
Methylation
Protons
Hemophagocytic Lymphohistiocytosis
Uvea
Trabecular Meshwork
Vision Disorders
Virus Diseases

HIF-1α- Targeting Acriflavine Provides Long Term Survival and Radiological Tumor Response in Brain Cancer Therapy

Mangraviti, A. , Raghavan, T. , Volpin, F. , Skuli, N. , Gullotti, D. , Zhou, J. , Asnaghi, L. , Sankey, E. , Liu, A. , Wang, Y. , Lee, D. H. , Gorelick, N. , Serra, R. , Peters, M. , Schriefer, D. , Delaspre, F. , Rodriguez, F. J. , Eberhart, C. G. , Brem, H. , Olivi, A. & 1 others Tyler, B., Dec 1 2017, In : Scientific Reports. 7, 1, 14978

Research output: Contribution to journalArticle

Acriflavine
Brain Neoplasms
Survival
Neoplasms
Glioma

Hypoxia inhibits growth, proliferation, and increases response to chemotherapy in retinoblastoma cells

Yang, Q., Tripathy, A., Yu, W., Eberhart, C. G. & Asnaghi, L., Sep 1 2017, In : Experimental Eye Research. 162, p. 48-61 14 p.

Research output: Contribution to journalArticle

Retinoblastoma
Drug Therapy
Growth
Glycolysis
Protein-Lysine 6-Oxidase

Inhibition of soluble epoxide hydrolase prevents diabetic retinopathy

Hu, J. , Dziumbla, S. , Lin, J. , Bibli, S. I. , Zukunft, S. , De Mos, J. , Awwad, K. , Frömel, T. , Jungmann, A. , Devraj, K. , Cheng, Z. , Wang, L. , Fauser, S. , Eberhart, C. G. , Sodhi, A. , Hammock, B. D. , Liebner, S. , Müller, O. J. , Glaubitz, C. , Hammes, H. P. & 2 others Popp, R. & Fleming, I., Dec 14 2017, In : Nature. 552, 7684, p. 248-252 5 p.

Research output: Contribution to journalArticle

Epoxide Hydrolases
Diabetic Retinopathy
Pericytes
Blood Vessels
Retina

Intertumoral Heterogeneity within Medulloblastoma Subgroups

Cavalli, F. M. G. , Remke, M. , Rampasek, L. , Peacock, J. , Shih, D. J. H. , Luu, B. , Garzia, L. , Torchia, J. , Nor, C. , Morrissy, A. S. , Agnihotri, S. , Thompson, Y. Y. , Kuzan-Fischer, C. M. , Farooq, H. , Isaev, K. , Daniels, C. , Cho, B. K. , Kim, S. K. , Wang, K. C. , Lee, J. Y. & 75 others Grajkowska, W. A., Perek-Polnik, M., Vasiljevic, A., Faure-Conter, C., Jouvet, A., Giannini, C., Nageswara Rao, A. A., Li, K. K. W., Ng, H. K., Eberhart, C. G., Pollack, I. F., Hamilton, R. L., Gillespie, G. Y., Olson, J. M., Leary, S., Weiss, W. A., Lach, B., Chambless, L. B., Thompson, R. C., Cooper, M. K., Vibhakar, R., Hauser, P., van Veelen, M. L. C., Kros, J. M., French, P. J., Ra, Y. S., Kumabe, T., López-Aguilar, E., Zitterbart, K., Sterba, J., Finocchiaro, G., Massimino, M., Van Meir, E. G., Osuka, S., Shofuda, T., Klekner, A., Zollo, M., Leonard, J. R., Rubin, J. B., Jabado, N., Albrecht, S., Mora, J., Van Meter, T. E., Jung, S., Moore, A. S., Hallahan, A. R., Chan, J. A., Tirapelli, D. P. C., Carlotti, C. G., Fouladi, M., Pimentel, J., Faria, C. C., Saad, A. G., Massimi, L., Liau, L. M., Wheeler, H., Nakamura, H., Elbabaa, S. K., Perezpeña-Diazconti, M., Chico Ponce de León, F., Robinson, S., Zapotocky, M., Lassaletta, A., Huang, A., Hawkins, C. E., Tabori, U., Bouffet, E., Bartels, U., Dirks, P. B., Rutka, J. T., Bader, G. D., Reimand, J., Goldenberg, A., Ramaswamy, V. & Taylor, M. D., Jun 12 2017, In : Cancer Cell. 31, 6, p. 737-754.e6

Research output: Contribution to journalArticle

Medulloblastoma
DNA Methylation
Cluster Analysis
Clinical Trials
Genome

Melanoma subtypes demonstrate distinct PD-L1 expression profiles

Kaunitz, G. J., Cottrell, T. R., Lilo, M., Muthappan, V., Esandrio, J., Berry, S., Xu, H., Ogurtsova, A., Anders, R. A., Fischer, A. H., Kraft, S., Gerstenblith, M. R., Thompson, C. L., Honda, K., Cuda, J. D., Eberhart, C. G., Handa, J. T., Lipson, E. J. & Taube, J. M., Sep 1 2017, In : Laboratory Investigation. 97, 9, p. 1063-1071 9 p.

Research output: Contribution to journalArticle

Melanoma
Solar System
Tumor-Infiltrating Lymphocytes
Tumor Microenvironment
Extremities

mTORC1-Mediated Inhibition of 4EBP1 Is Essential for Hedgehog Signaling-Driven Translation and Medulloblastoma

Wu, C. C., Hou, S., Orr, B. A., Kuo, B. R., Youn, Y. H., Ong, T., Roth, F., Eberhart, C. G., Robinson, G. W., Solecki, D. J., Taketo, M. M., Gilbertson, R. J., Roussel, M. F. & Han, Y. G., Dec 18 2017, In : Developmental Cell. 43, 6, p. 673-688.e5

Research output: Contribution to journalArticle

Medulloblastoma
Hedgehogs
Sirolimus
Growth and Development
Cerebellum

Predicting IDH mutation status in grade II gliomas using amide proton transfer-weighted (APTw) MRI

Jiang, S., Zou, T., Eberhart, C. G., Villalobos, M. A. V., Heo, H. Y., Zhang, Y., Wang, Y., Wang, X., Yu, H., Du, Y., van Zijl, P. C. M., Wen, Z. & Zhou, J., Sep 1 2017, In : Magnetic Resonance in Medicine. 78, 3, p. 1100-1109 10 p.

Research output: Contribution to journalArticle

Isocitrate Dehydrogenase
Amides
Glioma
Protons
Mutation

Rabbit model of human gliomas: Implications for intra-arterial drug delivery

Qin, H., Janowski, M., Pearl, M. S., Malysz-Cymborska, I., Li, S., Eberhart, C. G. & Walczak, P., Jan 1 2017, In : PLoS One. 12, 1, e0169656

Research output: Contribution to journalArticle

Drug delivery
Glioma
Tumors
rabbits
Rabbits

Strategies to enhance the distribution of nanotherapeutics in the brain

Zhang, C., Mastorakos, P., Sobral, M., Berry, S., Song, E., Nance, E., Eberhart, C. G., Hanes, J. & Suk, J. S., 2017, (Accepted/In press) In : Journal of Controlled Release.

Research output: Contribution to journalArticle

Nanoparticles
Convection
Brain
Blood-Brain Barrier
Extracellular Matrix

The dual mTOR kinase inhibitor TAK228 inhibits tumorigenicity and enhances radiosensitization in diffuse intrinsic pontine glioma

Miyahara, H., Yadavilli, S., Natsumeda, M., Rubens, J. A., Rodgers, L., Kambhampati, M., Taylor, I. C., Kaur, H., Asnaghi, L., Eberhart, C. G., Warren, K. E., Nazarian, J. & Raabe, E. H., Aug 1 2017, In : Cancer Letters. 400, p. 110-116 7 p.

Research output: Contribution to journalArticle

Glioma
Phosphotransferases
Brain Stem Neoplasms
Apoptosis
S 6

The TORC1/2 inhibitor TAK228 sensitizes atypical teratoid rhabdoid tumors to cisplatin-induced cytotoxicity

Rubens, J. A., Wang, S. Z., Price, A., Weingart, M. F., Allen, S. J., Orr, B. A., Eberhart, C. G. & Raabe, E. H., Oct 1 2017, In : Neuro-Oncology. 19, 10, p. 1361-1371 11 p.

Research output: Contribution to journalArticle

Cisplatin
Sirolimus
Heterografts
Apoptosis
Neoplasms
2016

Alterations in cellular metabolome after pharmacological inhibition of Notch in glioblastoma cells

Kahlert, U. D., Cheng, M., Koch, K., Marchionni, L., Fan, X., Raabe, E. H., Maciaczyk, J., Glunde, K. & Eberhart, C. G., Mar 1 2016, In : International Journal of Cancer. 138, 5, p. 1246-1255 10 p.

Research output: Contribution to journalArticle

Metabolome
Glioblastoma
Glutamic Acid
Pharmacology
Glutaminase

Altered gene expression in conjunctival squamous cell carcinoma

Mahale, A., Alkatan, H., Alwadani, S., Othman, M., Suarez, M. J., Price, A., Al-Hussain, H., Jastaneiah, S., Yu, W., Maktabi, A., Deepak, E. P., Eberhart, C. G. & Asnaghi, L., Feb 26 2016, (Accepted/In press) In : Modern Pathology.

Research output: Contribution to journalArticle

Matrix Metalloproteinases
Squamous Cell Carcinoma
Clusterin
Gene Expression
Carcinoma in Situ

Convection enhanced delivery of cisplatin-loaded brain penetrating nanoparticles cures malignant glioma in rats

Zhang, C., Nance, E. A., Mastorakos, P., Chisholm, J., Berry, S., Eberhart, C., Tyler, B., Brem, H., Suk, J. S. & Hanes, J., Dec 5 2016, (Accepted/In press) In : Journal of Controlled Release.

Research output: Contribution to journalArticle

Convection
Glioma
Nanoparticles
Cisplatin
Brain

Divergent clonal selection dominates medulloblastoma at recurrence

Morrissy, A. S. , Garzia, L. , Shih, D. J. H. , Zuyderduyn, S. , Huang, X. , Skowron, P. , Remke, M. , Cavalli, F. M. G. , Ramaswamy, V. , Lindsay, P. E. , Jelveh, S. , Donovan, L. K. , Wang, X. , Luu, B. , Zayne, K. , Li, Y. , Mayoh, C. , Thiessen, N. , Mercier, E. , Mungall, K. L. & 118 others Ma, Y., Tse, K., Zeng, T., Shumansky, K., Roth, A. J. L., Shah, S., Farooq, H., Kijima, N., Holgado, B. L., Lee, J. J. Y., Matan-Lithwick, S., Liu, J., Mack, S. C., Manno, A., Michealraj, K. A., Nor, C., Peacock, J., Qin, L., Reimand, J., Rolider, A., Thompson, Y. Y., Wu, X., Pugh, T., Ally, A., Bilenky, M., Butterfield, Y. S. N., Carlsen, R., Cheng, Y., Chuah, E., Corbett, R. D., Dhalla, N., He, A., Lee, D., Li, H. I., Long, W., Mayo, M., Plettner, P., Qian, J. Q., Schein, J. E., Tam, A., Wong, T., Birol, I., Zhao, Y., Faria, C. C., Pimentel, J., Nunes, S., Shalaby, T., Grotzer, M., Pollack, I. F., Hamilton, R. L., Li, X. N., Bendel, A. E., Fults, D. W., Walter, A. W., Kumabe, T., Tominaga, T., Collins, V. P., Cho, Y. J., Hoffman, C., Lyden, D., Wisoff, J. H., Garvin, J. H., Stearns, D. S., Massimi, L., Schüller, U., Sterba, J., Zitterbart, K., Puget, S., Ayrault, O., Dunn, S. E., Tirapelli, D. P. C., Carlotti, C. G., Wheeler, H., Hallahan, A. R., Ingram, W., MacDonald, T. J., Olson, J. J., Van Meir, E. G., Lee, J. Y., Wang, K. C., Kim, S. K., Cho, B. K., Pietsch, T., Fleischhack, G., Tippelt, S., Ra, Y. S., Bailey, S., Lindsey, J. C., Clifford, S. C., Eberhart, C. G., Cooper, M. K., Packer, R. J., Massimino, M., Garre, M. L., Bartels, U., Tabori, U., Hawkins, C. E., Dirks, P., Bouffet, E., Rutka, J. T., Wechsler-Reya, R. J., Weiss, W. A., Collier, L. S., Dupuy, A. J., Korshunov, A., Jones, D. T. W., Kool, M., Northcott, P. A., Pfister, S. M., Largaespada, D. A., Mungall, A. J., Moore, R. A., Jabado, N., Bader, G. D., Jones, S. J. M., Malkin, D., Marra, M. A. & Taylor, M. D., Jan 21 2016, In : Nature. 529, 7586, p. 351-357 7 p.

Research output: Contribution to journalArticle

Medulloblastoma
Recurrence
Image-Guided Radiotherapy
Neoplasms
Therapeutics

Establishment and biological characterization of a panel of glioblastoma multiforme (GBM) and GBM variant oncosphere cell lines

Binder, Z. A., Wilson, K. M., Salmasi, V., Orr, B. A., Eberhart, C. G., Siu, I. M., Lim, M., Weingart, J. D., Quinones-Hinojosa, A., Bettegowda, C., Kassam, A. B., Olivi, A., Brem, H., Riggins, G. J. & Gallia, G. L., Mar 1 2016, In : PLoS One. 11, 3, e0150271

Research output: Contribution to journalArticle

oncospheres
Glioblastoma
Tumors
Cells
cell lines

Expression of p16 and p53 in intraepithelial periocular sebaceous carcinoma

Bell, W. R., Singh, K., Anand Rajan, K. D. & Eberhart, C. G., Jan 1 2016, In : Ocular Oncology and Pathology. 2, 2, p. 71-75 5 p.

Research output: Contribution to journalArticle

Carcinoma in Situ
Carcinoma
Neoplasms
Conjunctiva
Immunohistochemistry

Hypoxia-inducible factor 1 upregulation of both VEGF and ANGPTL4 is required to promote the angiogenic phenotype in uveal melanoma

Hu, K., Babapoor-Farrokhran, S., Rodrigues, M., Deshpande, M., Puchner, B., Kashiwabuchi, F., Hassan, S. J., Asnaghi, L., Handa, J. T., Merbs, S., Eberhart, C. G., Semenza, G. L., Montaner, S. & Sodhi, A., 2016, In : Oncotarget. 7, 7, p. 7816-7828 13 p.

Research output: Contribution to journalArticle

Hypoxia-Inducible Factor 1
Vascular Endothelial Growth Factor A
Up-Regulation
Phenotype
Uveal melanoma

Multiple cilia suppress tumour formation

Eberhart, C., Mar 30 2016, In : Nature Cell Biology. 18, 4, p. 368-369 2 p.

Research output: Contribution to journalShort survey

Notch1 Receptor
Choroid Plexus Neoplasms
Hedgehog Proteins
Cilia
Cell Proliferation

MYB-QKI rearrangements in angiocentric glioma drive tumorigenicity through a tripartite mechanism

Bandopadhayay, P. , Ramkissoon, L. A. , Jain, P. , Bergthold, G. , Wala, J. , Zeid, R. , Schumacher, S. E. , Urbanski, L. , O'Rourke, R. , Gibson, W. J. , Pelton, K. , Ramkissoon, S. H. , Han, H. J. , Zhu, Y. , Choudhari, N. , Silva, A. , Boucher, K. , Henn, R. E. , Kang, Y. J. , Knoff, D. & 42 others Paolella, B. R., Gladden-Young, A., Varlet, P., Pages, M., Horowitz, P. M., Federation, A., Malkin, H., Tracy, A. A., Seepo, S., Ducar, M., Van Hummelen, P., Santi, M., Buccoliero, A. M., Scagnet, M., Bowers, D. C., Giannini, C., Puget, S., Hawkins, C., Tabori, U., Klekner, A., Bognar, L., Burger, P. C., Eberhart, C., Rodriguez, F. J., Hill, D. A., Mueller, S., Haas-Kogan, D. A., Phillips, J. J., Santagata, S., Stiles, C. D., Bradner, J. E., Jabado, N., Goren, A., Grill, J., Ligon, A. H., Goumnerova, L., Waanders, A. J., Storm, P. B., Kieran, M. W., Ligon, K. L., Beroukhim, R. & Resnick, A. C., Mar 1 2016, In : Nature Genetics. 48, 3, p. 273-282 10 p.

Research output: Contribution to journalArticle

Glioma
Pediatrics
Epigenomics
Neoplasms
Carcinogenesis

Somatic cell transfer of c-Myc and Bcl-2 induces large-cell anaplastic medulloblastomas in mice

Jenkins, N. C., Rao, G., Eberhart, C. G., Pedone, C. A., Dubuc, A. M. & Fults, D. W., Feb 1 2016, In : Journal of Neuro-Oncology. 126, 3, p. 415-424 10 p.

Research output: Contribution to journalArticle

Medulloblastoma
Neoplasms
Brain Neoplasms
Stem Cells
Nestin

Somatic mutations of DICER1 and KMT2D are frequent in intraocular medulloepitheliomas

Sahm, F., Jakobiec, F. A., Meyer, J., Schrimpf, D., Eberhart, C. G., Hovestadt, V., Capper, D., Lambo, S., Ryzhova, M., Schüller, U., Zheludkova, O., Kumirova, E., Lichter, P., von Deimling, A., Jones, D. T. W., Pfister, S. M., Kool, M. & Korshunov, A., 2016, (Accepted/In press) In : Genes Chromosomes and Cancer.

Research output: Contribution to journalArticle

Primitive Neuroectodermal Tumors
Mutation
Neoplasms
Neuroepithelial Neoplasms
Genome

Subepidermal Calcified Nodules of the Eyelid Differ in Children and Adults

AlWadani, S., Suarez, M. J., Kass, J. J., MacQuaid, E., Edward, D. P., Alkatan, H. & Eberhart, C., Jul 29 2016, (Accepted/In press) In : Ophthalmic Plastic and Reconstructive Surgery.

Research output: Contribution to journalArticle

Eyelids
Foreign-Body Reaction
Inflammation
Calcinosis
Gout

Targeting Notch Signaling and Autophagy Increases Cytotoxicity in Glioblastoma Neurospheres

Natsumeda, M., Maitani, K., Liu, Y., Miyahara, H., Kaur, H., Chu, Q., Zhang, H., D. Kahlert, U. & Eberhart, C. G., Nov 1 2016, In : Brain Pathology. 26, 6, p. 713-723 11 p.

Research output: Contribution to journalArticle

Autophagy
Glioblastoma
Glioma
Stem Cells
Amyloid Precursor Protein Secretases

Targeting Notch signaling as a novel therapy for retinoblastoma

Asnaghi, L., Tripathy, A., Yang, Q., Kaur, H., Hanaford, A., Yu, W. & Eberhart, C. G., 2016, In : Oncotarget. 7, 43, p. 70028-70044 17 p.

Research output: Contribution to journalArticle

Retinoblastoma
Therapeutics
Small Interfering RNA
Down-Regulation
Amyloid Precursor Protein Secretases

Therapeutic impact of cytoreductive surgery and irradiation of posterior fossa ependymoma in the molecular era: A retrospective multicohort analysis

Ramaswamy, V. , Hielscher, T. , Mack, S. C. , Lassaletta, A. , Lin, T. , Pajtler, K. W. , Jones, D. T. W. , Luu, B. , Cavalli, F. M. G. , Aldape, K. , Remke, M. , Mynarek, M. , Rutkowski, S. , Gururangan, S. , McLendon, R. E. , Lipp, E. S. , Dunham, C. , Hukin, J. , Eisenstat, D. D. , Fulton, D. & 95 others Van Landeghem, F. K. H., Santi, M., Van Veelen, M. L. C., Van Meir, E. G., Osuka, S., Fan, X., Muraszko, K. M., Tirapelli, D. P. C., Oba-Shinjo, S. M., Marie, S. K. N., Carlotti, C. G., Lee, J. Y., Rao, A. A. N., Giannini, C., Faria, C. C., Nunes, S., Mora, J., Hamilton, R. L., Hauser, P., Jabado, N., Petrecca, K., Jung, S., Massimi, L., Zollo, M., Cinalli, G., Bognár, L., Klekner, A., Hortobágyi, T., Leary, S., Ermoian, R. P., Olson, J. M., Leonard, J. R., Gardner, C., Grajkowska, W. A., Chambless, L. B., Cain, J., Eberhart, C. G., Ahsan, S., Massimino, M., Giangaspero, F., Buttarelli, F. R., Packer, R. J., Emery, L., Yong, W. H., Soto, H., Liau, L. M., Everson, R., Grossbach, A., Shalaby, T., Grotzer, M., Karajannis, M. A., Zagzag, D., Wheeler, H., Von Hoff, K., Alonso, M. M., Tuñon, T., Schüller, U., Zitterbart, K., Sterba, J., Chan, J. A., Guzman, M., Elbabaa, S. K., Colman, H., Dhall, G., Fisher, P. G., Fouladi, M., Gajjar, A., Goldman, S., Hwang, E., Kool, M., Ladha, H., Vera-Bolanos, E., Wani, K., Lieberman, F., Mikkelsen, T., Omuro, A. M., Pollack, I. F., Prados, M., Robins, H. I., Soffietti, R., Wu, J., Metellus, P., Tabori, U., Bartels, U., Bouffet, E., Hawkins, C. E., Rutka, J. T., Dirks, P., Pfister, S. M., Merchant, T. E., Gilbert, M. R., Armstrong, T. S., Korshunov, A., Ellison, D. W. & Taylor, M. D., Jul 20 2016, In : Journal of Clinical Oncology. 34, 21, p. 2468-2477 10 p.

Research output: Contribution to journalArticle

Ependymoma
Radiotherapy
Biomarkers
Radiation
Therapeutics

The transcriptional modulator HMGA2 promotes stemness and tumorigenicity in glioblastoma

Kaur, H., Ali, S. Z., Huey, L., Hütt-Cabezas, M., Taylor, I., Mao, X. G., Weingart, M., Chu, Q., Rodriguez, F. J., Eberhart, C. G. & Raabe, E. H., Jul 10 2016, In : Cancer Letters. 377, 1, p. 55-64 10 p.

Research output: Contribution to journalArticle

AT-Hook Motifs
Glioblastoma
Stem Cell Factor
Neoplastic Stem Cells
Tumor Cell Line
2015

Analysis of varicella-zoster virus in temporal arteries biopsy positive and negative for giant cell arteritis

Nagel, M. A. , White, T. , Khmeleva, N. , Rempel, A. , Boyer, P. J. , Bennett, J. L. , Haller, A. , Lear-Kaul, K. , Kandasmy, B. , Amato, M. , Wood, E. , Durairaj, V. , Fogt, F. , Tamhankar, M. A. , Grossniklaus, H. E. , Poppiti, R. J. , Bockelman, B. , Keyvani, K. , Pollak, L. , Mendlovic, S. & 7 others Fowkes, M., Eberhart, C. G., Buttmann, M., Toyka, K. V., Meyer-Ter-Vehn, T., Petursdottir, V. & Gilden, D., Nov 1 2015, In : JAMA Neurology. 72, 11, p. 1281-1287 7 p.

Research output: Contribution to journalArticle

Temporal Arteries
Giant Cell Arteritis
Human Herpesvirus 3
Biopsy
Antigens