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2017

Analysis of Agreement of Retinal-Layer Thickness Measures Derived from the Segmentation of Horizontal and Vertical Spectralis OCT Macular Scans

Gonzalez Caldito, N., Antony, B., He, Y., Lang, A., Nguyen, J., Rothman, A., Ogbuokiri, E., Avornu, A., Balcer, L., Frohman, E., Frohman, T. C., Bhargava, P., Prince, J. L., Calabresi, P. & Saidha, S., Dec 15 2017, (Accepted/In press) In : Current Eye Research. p. 1-9 9 p.

Research output: Contribution to journalArticle

Retinaldehyde
Optical Coherence Tomography
Multiple Sclerosis
Nerve Fibers
Ganglia

B-cell depletion - A frontier in monoclonal antibodies for multiple sclerosis

Calabresi, P., Jan 19 2017, In : New England Journal of Medicine. 376, 3, p. 280-282 3 p.

Research output: Contribution to journalEditorial

Murine-Derived Monoclonal Antibodies
CD20 Antigens
Antibodies, Monoclonal, Humanized
Multiple Sclerosis
B-Lymphocytes

Characteristics of morphologic macular abnormalities in neuroimmunology practice

Al-Louzi, O., Sotirchos, E. S., Vidal-Jordana, A., Beh, S. C., Button, J., Ying, H. S., Balcer, L. J., Frohman, E. M., Saidha, S., Calabresi, P. & Newsome, S., Nov 1 2017, (Accepted/In press) In : Multiple Sclerosis Journal.

Research output: Contribution to journalArticle

Odds Ratio
Optical Coherence Tomography
Matrix Metalloproteinases
Epiretinal Membrane
Ophthalmology

CNS-targeted autoimmunity leads to increased influenza mortality in mice

Glenn, J. D., Smith, M. D., Xue, P., Chan-Li, Y., Collins, S. L., Calabresi, P., Horton, M. & Whartenby, K., 2017, In : Journal of Experimental Medicine. 214, 2, p. 297-307 11 p.

Research output: Contribution to journalArticle

Autoimmune Experimental Encephalomyelitis
Autoimmunity
Human Influenza
Central Nervous System
Lung

Disease-modifying therapies modulate retinal atrophy in multiple sclerosis: A retrospective study

Button, J., Al-Louzi, O., Lang, A., Bhargava, P., Newsome, S., Frohman, T., Balcer, L. J., Frohman, E. M., Prince, J. L., Calabresi, P. & Saidha, S., Feb 7 2017, In : Neurology. 88, 6, p. 525-532 8 p.

Research output: Contribution to journalArticle

Optical Coherence Tomography
Multiple Sclerosis
Atrophy
Relapsing-Remitting Multiple Sclerosis
Retrospective Studies

From neurofilament research to multiple sclerosis clinical practice: Where do we stand?

Bodini, B. & Calabresi, P., Feb 28 2017, In : Neurology. 88, 9, p. 816-817 2 p.

Research output: Contribution to journalEditorial

Intermediate Filaments
Multiple Sclerosis
Research

Gradient nonlinearity effects on upper cervical spinal cord area measurement from 3D T1-weighted brain MRI acquisitions

Papinutto, N., Bakshi, R., Bischof, A., Calabresi, P., Caverzasi, E., Constable, R. T., Datta, E., Kirkish, G., Nair, G., Oh, J., Pelletier, D., Pham, D. L., Reich, D. S., Rooney, W., Roy, S., Schwartz, D., Shinohara, R. T., Sicotte, N. L., Stern, W. A., Tagge, I. & 3 othersTauhid, S., Tummala, S. & Henry, R. G., 2017, (Accepted/In press) In : Magnetic Resonance in Medicine.

Research output: Contribution to journalArticle

Brain
Multiple Sclerosis
Healthy Volunteers
Cervical Cord

Lineage tracing reveals dynamic changes in oligodendrocyte precursor cells following cuprizone-induced demyelination

Baxi, E. G., Debruin, J., Jin, J., Strasburger, H. J., Smith, M. D., Orthmann-Murphy, J. L., Schott, J. T., Fairchild, A. N., Bergles, D. E. & Calabresi, P., 2017, (Accepted/In press) In : GLIA.

Research output: Contribution to journalArticle

Cuprizone
Oligodendroglia
Demyelinating Diseases
Stem Cells
Corpus Callosum

Longitudinal multiple sclerosis lesion segmentation: Resource and challenge

Carass, A., Roy, S., Jog, A., Cuzzocreo, J. L., Magrath, E., Gherman, A., Button, J., Nguyen, J., Prados, F., Sudre, C. H., Jorge Cardoso, M., Cawley, N., Ciccarelli, O., Wheeler-Kingshott, C. A. M., Ourselin, S., Catanese, L., Deshpande, H., Maurel, P., Commowick, O., Barillot, C. & 26 othersTomas-Fernandez, X., Warfield, S. K., Vaidya, S., Chunduru, A., Muthuganapathy, R., Krishnamurthi, G., Jesson, A., Arbel, T., Maier, O., Handels, H., Iheme, L. O., Unay, D., Jain, S., Sima, D. M., Smeets, D., Ghafoorian, M., Platel, B., Birenbaum, A., Greenspan, H., Bazin, P. L., Calabresi, P., Crainiceanu, C. M., Ellingsen, L. M., Reich, D. S., Prince, J. L. & Pham, D. L., Mar 1 2017, In : NeuroImage. 148, p. 77-102 26 p.

Research output: Contribution to journalArticle

Multiple Sclerosis
Research Personnel
Research
Datasets

Longitudinal multiple sclerosis lesion segmentation data resource

Carass, A., Roy, S., Jog, A., Cuzzocreo, J. L., Magrath, E., Gherman, A., Button, J., Nguyen, J., Bazin, P. L., Calabresi, P., Crainiceanu, C. M., Ellingsen, L. M., Reich, D. S., Prince, J. L. & Pham, D. L., Jun 1 2017, In : Data in Brief. 12, p. 346-350 5 p.

Research output: Contribution to journalArticle

multiple sclerosis
resources
segmentation
website
expert

Multiple Sclerosis Lesion Segmentation Using Joint Label Fusion

Dong, M., Oguz, I., Subbana, N., Calabresi, P., Shinohara, R. T. & Yushkevich, P., 2017, Patch-Based Techniques in Medical Imaging - 3rd International Workshop, Patch-MI 2017 Held in Conjunction with MICCAI 2017, Proceedings. Springer Verlag, Vol. 10530 LNCS. p. 138-145 8 p. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); vol. 10530 LNCS).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Multiple Sclerosis
Atlas
Labels
Fusion
Fusion reactions

Neuropsychiatric syndromes of multiple sclerosis

Murphy, R., O'Donoghue, S., Counihan, T., McDonald, C., Calabresi, P., Ahmed, M. A. S., Kaplin, A. I. & Hallahan, B., Aug 1 2017, In : Journal of Neurology, Neurosurgery and Psychiatry. 88, 8, p. 697-708 12 p.

Research output: Contribution to journalReview article

Multiple Sclerosis
Neuroimaging
Signs and Symptoms
Disease Progression
Mental Health
Optical Coherence Tomography
Multiple Sclerosis
Neurodegenerative Diseases
Biomarkers
Technology
Relapsing-Remitting Multiple Sclerosis
Randomized Controlled Trials
Magnetic Resonance Imaging
Odds Ratio
Brain

Quantitative measures of walking and strength provide insight into brain corticospinal tract pathology in multiple sclerosis

Fritz, N. E., Keller, J., Calabresi, P. & Zackowski, K. M., 2017, In : NeuroImage: Clinical. 14, p. 490-498 9 p.

Research output: Contribution to journalArticle

Pyramidal Tracts
Multiple Sclerosis
Walking
Pathology
Brain

Retinal architecture and melanopsin-mediated pupillary response characteristics: A putative pathophysiologic signature for the retino-hypothalamic tract in multiple sclerosis

Meltzer, E., Sguigna, P. V., Subei, A., Beh, S., Kildebeck, E., Conger, D., Conger, A., Lucero, M., Frohman, B. S., Frohman, A. N., Saidha, S., Galetta, S., Calabresi, P., Rennaker, R., Frohman, T. C., Kardon, R. H., Balcer, L. J. & Frohman, E. M., May 1 2017, In : JAMA Neurology. 74, 5, p. 574-582 9 p.

Research output: Contribution to journalArticle

Multiple Sclerosis
Constriction
Optical Coherence Tomography
Light
Retina

Retinal degeneration in primary-progressive multiple sclerosis: A role for cortical lesions?

Petracca, M., Cordano, C., Cellerino, M., Button, J., Krieger, S., Vancea, R., Ghassemi, R., Farrell, C., Miller, A., Calabresi, P., Lublin, F. & Inglese, M., 2017, In : Multiple Sclerosis. 23, 1, p. 43-50 8 p.

Research output: Contribution to journalArticle

Chronic Progressive Multiple Sclerosis
Retinal Degeneration
Ganglia
Nerve Fibers
Visual Pathways

Retinal layer segmentation in multiple sclerosis: a systematic review and meta-analysis

ERN-EYE IMSVISUAL, Oct 1 2017, In : The Lancet Neurology. 16, 10, p. 797-812 16 p.

Research output: Contribution to journalArticle

Multiple Sclerosis
Meta-Analysis
Optic Neuritis
Nerve Fibers
Optical Coherence Tomography

Retrograde trans-synaptic visual pathway degeneration in multiple sclerosis: A case series

Al-Louzi, O., Button, J., Newsome, S., Calabresi, P. & Saidha, S., Jun 1 2017, In : Multiple Sclerosis. 23, 7, p. 1035-1039 5 p.

Research output: Contribution to journalArticle

Retrograde Degeneration
Visual Pathways
Ganglia
Multiple Sclerosis
Nervous System

Thalamus segmentation using multi-modal feature classification: Validation and pilot study of an age-matched cohort

Glaister, J., Carass, A., NessAiver, T., Stough, J. V., Saidha, S., Calabresi, P. & Prince, J. L., Sep 1 2017, In : NeuroImage. 158, p. 430-440 11 p.

Research output: Contribution to journalArticle

Validation Studies
Thalamus
Diffusion Tensor Imaging
Atlases
Multiple Sclerosis

The NAIMS cooperative pilot project: Design, implementation and future directions

on behalf of the NAIMS Cooperative Steering Committee, Oct 1 2017, (Accepted/In press) In : Multiple Sclerosis Journal.

Research output: Contribution to journalArticle

Multiple Sclerosis
Magnetic Resonance Imaging
Multicenter Studies
Direction compound
Research

Therapeutic Application of Monoclonal Antibodies in Multiple Sclerosis

Orthmann-Murphy, J. L. & Calabresi, P., Jan 1 2017, In : Clinical Pharmacology and Therapeutics. 101, 1, p. 52-64 13 p.

Research output: Contribution to journalArticle

Multiple Sclerosis
Monoclonal Antibodies
Therapeutics
Central Nervous System
Immunomodulation

Towards topological correct segmentation of macular OCT from cascaded FCNs

He, Y., Carass, A., Yun, Y., Zhao, C., Jedynak, B. M., Solomon, S., Saidha, S., Calabresi, P. & Prince, J. L., 2017, Fetal, Infant and Ophthalmic Medical Image Analysis - International Workshop, FIFI 2017 and 4th International Workshop, OMIA 2017 Held in Conjunction with MICCAI 2017, Proceedings. Springer Verlag, Vol. 10554 LNCS. p. 202-209 8 p. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); vol. 10554 LNCS).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Optical Coherence Tomography
Optical tomography
Retina
Segmentation
Topology

Volumetric analysis from a harmonized multisite brain MRI study of a single subject with multiple sclerosis

Shinohara, R. T., Oh, J., Nair, G., Calabresi, P., Davatzikos, C., Doshi, J., Henry, R. G., Kim, G., Linn, K. A., Papinutto, N., Pelletier, D., Pham, D. L., Reich, D. S., Rooney, W., Roy, S., Stern, W., Tummala, S., Yousuf, F., Zhu, A., Sicotte, N. L. & 1 othersBakshi, R., Aug 1 2017, In : American Journal of Neuroradiology. 38, 8, p. 1501-1509 9 p.

Research output: Contribution to journalArticle

Multiple Sclerosis
Brain
Multicenter Studies
Atrophy
Volunteers
2016

20/40 or better visual acuity after optic neuritis: Not as good as we once thought?

Sabadia, S. B., Nolan, R. C., Galetta, K. M., Narayana, K. M., Wilson, J. A., Calabresi, P., Frohman, E. M., Galetta, S. L. & Balcer, L. J., 2016, In : Journal of Neuro-Ophthalmology. 36, 4, p. 369-376 8 p.

Research output: Contribution to journalArticle

Optic Neuritis
Visual Acuity
Nerve Fibers
Ganglia
Quality of Life

Adapted resistance training improves strength in eight weeks in individuals with multiple sclerosis

Keller, J. L., Fritz, N., Chiang, C. C., Jiang, A., Thompson, T., Cornet, N., Newsome, S., Calabresi, P. & Zackowski, K., Jan 29 2016, In : Journal of Visualized Experiments. 2016, 107, e53449.

Research output: Contribution to journalArticle

Resistance Training
Multiple Sclerosis
Education
Hip
Direction compound

Author Response

Sotirchos, E. S. & Calabresi, P., Sep 27 2016, In : Neurology. 87, 13, p. 1424 1 p.

Research output: Contribution to journalLetter

Combined registration and motion correction of longitudinal retinal OCT data

Lang, A., Carass, A., Al-Louzi, O., Bhargava, P., Solomon, S., Calabresi, P. & Prince, J. L., 2016, Medical Imaging 2016: Image Processing. SPIE, Vol. 9784. 97840X

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Optical tomography
Optical Coherence Tomography
tomography
Thickness measurement
Eye movements

Differentiating neuromyelitis optica from other causes of longitudinally extensive transverse myelitis on spinal magnetic resonance imaging

Pekcevik, Y., Mitchell, C. H., Mealy, M. A., Orman, G., Lee, I. H., Newsome, S., Thompson, C., Pardo-Villamizar, C. A., Calabresi, P., Levy, M. & Izbudak, I., 2016, In : Multiple Sclerosis. 22, 3, p. 302-311 10 p.

Research output: Contribution to journalArticle

Transverse Myelitis
Neuromyelitis Optica
Magnetic Resonance Imaging
Spinal Cord
Brain

How global MS prevalence is changing: A retrospective chart review in the United Arab Emirates

Schiess, N., Huether, K., Fatafta, T., Fitzgerald, K. C., Calabresi, P., Blair, I., Alsaadi, T. & Szolics, M., Sep 1 2016, In : Multiple Sclerosis and Related Disorders. 9, p. 73-79 7 p.

Research output: Contribution to journalArticle

United Arab Emirates
Multiple Sclerosis
Middle East
Incidence
Age of Onset

Increased TNFR1 expression and signaling in injured peripheral nerves of mice with reduced BACE1 activity

Liu, L., Fissel, J. A., Tasnim, A., Borzan, J., Gocke, A., Calabresi, P. & Farah, M. H., Sep 1 2016, In : Neurobiology of Disease. 93, p. 21-27 7 p.

Research output: Contribution to journalArticle

Tumor Necrosis Factor Receptors
Peripheral Nerves
Enzymes
Macrophages
Knockout Mice

Intensity inhomogeneity correction of macular OCT using N3 and retinal flatspace

Lang, A., Carass, A., Jedynak, B. M., Solomon, S., Calabresi, P. & Prince, J. L., Jun 15 2016, 2016 IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI 2016 - Proceedings. IEEE Computer Society, Vol. 2016-June. p. 197-200 4 p. 7493243

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Optical tomography
Optical Coherence Tomography
Magnetic resonance imaging
Retina
Imaging techniques

Is my MS patient failing treatment?

Butzkueven, H. & Calabresi, P., Jul 12 2016, In : Neurology. 87, 2, p. 124-125 2 p.

Research output: Contribution to journalEditorial

Therapeutics

Lesion heterogeneity on high-field susceptibility MRI Is associated with multiple sclerosis severity

Harrison, D. M., Li, X., Liu, H., Jones, C., Caffo, B. S., Calabresi, P. & Van Zijl, P. C., Aug 1 2016, In : American Journal of Neuroradiology. 37, 8, p. 1447-1453 7 p.

Research output: Contribution to journalArticle

Multiple Sclerosis
Fatigue
Oligodendroglia
Iron
Inflammation

Magnetic susceptibility contrast variations in multiple sclerosis lesions

Li, X., Harrison, D. M., Liu, H., Jones, C., Oh, J., Calabresi, P. & Van Zijl, P. C., Feb 1 2016, In : Journal of Magnetic Resonance Imaging. 43, 2, p. 463-473 11 p.

Research output: Contribution to journalArticle

Multiple Sclerosis
Magnetic Resonance Imaging
Masks
Myelin Sheath
Iron

Metabolomics in multiple sclerosis

Bhargava, P. & Calabresi, P., Apr 1 2016, In : Multiple Sclerosis. 22, 4, p. 451-460 10 p.

Research output: Contribution to journalArticle

Metabolomics
Multiple Sclerosis
Precision Medicine
Demyelinating Diseases
Genomics

Multiple Sclerosis

Schiess, N. & Calabresi, P., Aug 1 2016, In : Seminars in Neurology. 36, 4, p. 350-356 7 p.

Research output: Contribution to journalArticle

Multiple Sclerosis
Immunomodulation
Neurology
Cognition
Differential Diagnosis

Outer retinal changes following acute optic neuritis

Al-Louzi, O. A., Bhargava, P., Newsome, S., Balcer, L. J., Frohman, E. M., Crainiceanu, C. M., Calabresi, P. & Saidha, S., 2016, In : Multiple Sclerosis. 22, 3, p. 362-372 11 p.

Research output: Contribution to journalArticle

Optic Neuritis
Ganglia
Optical Coherence Tomography
Nerve Fibers
Multiple Sclerosis

Pain, cognition and quality of life associate with structural measures of brain volume loss in multiple sclerosis

Fritz, N. E., Roy, S., Keller, J., Prince, J. L., Calabresi, P. & Zackowski, K. M., Oct 14 2016, In : NeuroRehabilitation. 39, 4, p. 535-544 10 p.

Research output: Contribution to journalArticle

Cognition
Multiple Sclerosis
Quality of Life
Pain
Brain

Phenytoin in acute optic neuritis: neuroprotective or not?

Saidha, S. & Calabresi, P., Mar 1 2016, In : The Lancet Neurology. 15, 3, p. 233-235 3 p.

Research output: Contribution to journalComment/debate

Voltage-Gated Sodium Channel Blockers
Optic Neuritis
Phenytoin
Neuroprotective Agents
Outcome Assessment (Health Care)
Myelin Proteins
Oligodendroglia
Neurology
Rats
Assays

Retinal thickness measured with optical coherence tomography and risk of disability worsening in multiple sclerosis: A cohort study

IMSVISUAL consortium, May 1 2016, In : The Lancet Neurology. 15, 6, p. 574-584 11 p.

Research output: Contribution to journalArticle

Optical Coherence Tomography
Optic Neuritis
Multiple Sclerosis
Cohort Studies
Nerve Fibers

Safety and immunologic effects of high-vs low-dose cholecalciferol in multiple sclerosis

Sotirchos, E. S., Bhargava, P., Eckstein, C., Van Haren, K., Baynes, M., Ntranos, A., Gocke, A., Steinman, L., Mowry, E. M. & Calabresi, P., Jan 26 2016, In : Neurology. 86, 4, p. 382-390 9 p.

Research output: Contribution to journalArticle

Cholecalciferol
Multiple Sclerosis
T-Lymphocytes
Safety
Interleukin-17

Simultaneous segmentation of retinal surfaces and microcystic macular edema in SDOCT volumes

Antony, B. J., Lang, A., Swingle, E. K., Al-Louzi, O., Carass, A., Solomon, S., Calabresi, P., Saidha, S. & Prince, J. L., 2016, Medical Imaging 2016: Image Processing. SPIE, Vol. 9784. 97841C

Research output: Chapter in Book/Report/Conference proceedingConference contribution

edema
Macular Edema
Optical tomography
Optical Coherence Tomography
Imaging techniques

Systemic tolerance mediated by melanoma brain tumors is reversible by radiotherapy and vaccination

Jackson, C. M., Kochel, C. M., Nirschl, C. J., Durham, N. M., Ruzevick, J., Alme, A., Francica, B. J., Elias, J., Daniels, A., Dubensky, T. W., Lauer, P., Brockstedt, D. G., Baxi, E. G., Calabresi, P., Taube, J. M., Pardo-Villamizar, C. A., Brem, H., Pardoll, A. M., Lim, M. & Drake, C. G., Mar 1 2016, In : Clinical Cancer Research. 22, 5, p. 1161-1172 12 p.

Research output: Contribution to journalArticle

Central Nervous System Neoplasms
Brain Neoplasms
Melanoma
Vaccination
Radiotherapy

Thalamus parcellation using multi-modal feature classification and thalamic nuclei priors

Glaister, J., Carass, A., Stough, J. V., Calabresi, P. & Prince, J. L., 2016, Medical Imaging 2016: Image Processing. SPIE, Vol. 9784. 97843J

Research output: Chapter in Book/Report/Conference proceedingConference contribution

thalamus
Thalamic Nuclei
Thalamus
nuclei
Neurodegenerative diseases

The APOSTEL recommendations for reporting quantitative optical coherence tomography studies

Cruz-Herranz, A., Balk, L. J., Oberwahrenbrock, T., Saidha, S., Martinez-Lapiscina, E. H., Lagreze, W. A., Schuman, J. S., Villoslada, P., Calabresi, P., Balcer, L., Petzold, A., Green, A. J., Paul, F., Brandt, A. U. & Albrecht, P., Jun 14 2016, In : Neurology. 86, 24, p. 2303-2309 7 p.

Research output: Contribution to journalReview article

Optical Coherence Tomography
Terminology
Consensus
Group Processes
Checklist

The emergence of neuroepidemiology, neurovirology and neuroimmunology: the legacies of John F. Kurtzke and Richard ‘Dick’ T. Johnson

Kildebeck, E. J., Narayan, R., Nath, A., Weiner, H., Beh, S., Calabresi, P., Steinman, L., Major, E. O., Frohman, T. C. & Frohman, E. M., Oct 12 2016, (Accepted/In press) In : Journal of Neurology. p. 1-12 12 p.

Research output: Contribution to journalArticle

Voxel based morphometry in optical coherence tomography: Validation & core findings

Antony, B. J., Chen, M., Carass, A., Jedynak, B. M., Al-Louzi, O., Solomon, S., Saidha, S., Calabresi, P. & Prince, J. L., 2016, Medical Imaging 2016: Biomedical Applications in Molecular, Structural, and Functional Imaging. SPIE, Vol. 9788. 97880P

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Optical tomography
Optical Coherence Tomography
tomography
Multiple Sclerosis
Neuroimaging