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2017

A pilot trial of the combination of vemurafenib with adoptive cell therapy in patients with metastatic melanoma

Deniger, D. C., Kwong, M. L. M., Pasetto, A., Dudley, M. E., Wunderlich, J. R., Langhan, M. M., Lee, C. C. R. & Rosenberg, S. A. Jan 15 2017 In : Clinical Cancer Research. 23, 2, p. 351-362 12 p.

Research output: Research - peer-reviewArticle

Cell- and Tissue-Based Therapy
Melanoma
PLX4032
Tumor-Infiltrating Lymphocytes
Neoplasms

Characterization of an immunogenic mutation in a patient with metastatic triple-negative breast cancer

Assadipour, Y., Zacharakis, N., Crystal, J. S., Prickett, T. D., Gartner, J. J., Somerville, R. P. T., Xu, H., Black, M. A., Jia, L., Chinnasamy, H., Kriley, I., Lu, L., Wunderlich, J. R., Zheng, Z., Lu, Y. C., Robbins, P. F., Rosenberg, S. A., Goff, S. L. & Feldman, S. A. Aug 1 2017 In : Clinical Cancer Research. 23, 15, p. 4347-4353 7 p.

Research output: Research - peer-reviewArticle

Triple Negative Breast Neoplasms
Mutation
Tumor-Infiltrating Lymphocytes
Neoplasms
Breast Neoplasms

Dual-specific chimeric antigen receptor T cells and an indirect vaccine eradicate a variety of large solid tumors in an immunocompetent, self-antigen setting

Slaney, C. Y., Von Scheidt, B., Davenport, A. J., Beavis, P. A., Westwood, J. A., Mardiana, S., Tscharke, D. C., Ellis, S., Prince, H. M., Trapani, J. A., Johnstone, R. W., Smyth, M. J., Teng, M. W., Ali, A., Yu, Z., Rosenberg, S. A., Restifo, N. P., Neeson, P., Darcy, P. K. & Kershaw, M. H. May 15 2017 In : Clinical Cancer Research. 23, 10, p. 2478-2490 13 p.

Research output: Research - peer-reviewArticle

Autoantigens
T-Cell Antigen Receptor
Vaccines
Neoplasms
T-Lymphocytes

Final common pathway' of human cancer immunotherapy: Targeting random somatic mutations

Tran, E., Robbins, P. F. & Rosenberg, S. A. Feb 15 2017 In : Nature Immunology. 18, 3, p. 255-262 8 p.

Research output: Research - peer-reviewReview article

Immunotherapy
Mutation
Neoplasms
Lymphocytes
Adoptive Transfer

Isolation of T-cell receptors specifically reactive with mutated tumor-associated antigens from tumor-infiltrating lymphocytes based on CD137 expression

Parkhurst, M., Gros, A., Pasetto, A., Prickett, T., Crystal, J. S., Robbins, P. & Rosenberg, S. A. May 15 2017 In : Clinical Cancer Research. 23, 10, p. 2491-2505 15 p.

Research output: Research - peer-reviewArticle

Tumor-Infiltrating Lymphocytes
Neoplasm Antigens
T-Cell Antigen Receptor
Neoplasms
T-Lymphocytes

Landscape of immunogenic tumor antigens in successful immunotherapy of virally induced epithelial cancer

Stevanović, S., Pasetto, A., Helman, S. R., Gartner, J. J., Prickett, T. D., Howie, B., Robins, H. S., Robbins, P. F., Klebanoff, C. A., Rosenberg, S. A. & Hinrichs, C. S. Apr 14 2017 In : Science. 356, 6334, p. 200-205 6 p.

Research output: Research - peer-reviewArticle

Neoplasm Antigens
Immunotherapy
Neoplasms
Viral Tumor Antigens
Cell Death

LIGHT elevation enhances immune eradication of colon cancer metastases

Qiao, G., Qin, J., Kunda, N., Calata, J. F., Mahmud, D. L., Gann, P., Fu, Y. X., Rosenberg, S. A., Prabhakar, B. S. & Maker, A. V. Apr 15 2017 In : Cancer Research. 77, 8, p. 1880-1891 12 p.

Research output: Research - peer-reviewArticle

Colonic Neoplasms
Neoplasm Metastasis
Light
Neoplasms
Liver

Long-Duration Complete Remissions of Diffuse Large B Cell Lymphoma after Anti-CD19 Chimeric Antigen Receptor T Cell Therapy

Kochenderfer, J. N., Somerville, R. P. T., Lu, T., Yang, J. C., Sherry, R. M., Feldman, S. A., McIntyre, L., Bot, A., Rossi, J., Lam, N. & Rosenberg, S. A. 2017 (Accepted/In press) In : Molecular Therapy.

Research output: Research - peer-reviewArticle

CD19 Antigens
Antigen Receptors
Lymphoma, Large B-Cell, Diffuse
Cell- and Tissue-Based Therapy
T-Lymphocytes

Lymphoma remissions caused by anti-CD19 chimeric antigen receptor T cells are associated with high serum interleukin-15 levels

Kochenderfer, J. N. , Somerville, R. P. T. , Lu, T. , Shi, V. , Bot, A. , Rossi, J. , Xue, A. , Goff, S. L. , Yang, J. C. , Sherry, R. M. , Klebanoff, C. A. , Kammula, U. S. , Sherman, M. , Perez, A. , Yuan, C. M. , Feldman, T. , Friedberg, J. W. , Roschewski, M. J. , Feldman, S. A. , McIntyre, L. & 2 others Toomey, M. A. & Rosenberg, S. A. Jun 1 2017 In : Journal of Clinical Oncology. 35, 16, p. 1803-1813 11 p.

Research output: Research - peer-reviewArticle

CD19 Antigens
Interleukin-15
Antigen Receptors
Lymphoma
T-Lymphocytes

Routine Computer Tomography Imaging for the Detection of Recurrences in High-Risk Melanoma Patients

Park, T. S., Phan, G. Q., Yang, J. C., Kammula, U., Hughes, M. S., Trebska-McGowan, K., Morton, K. E., White, D. E., Rosenberg, S. A. & Sherry, R. M. Jan 31 2017 (Accepted/In press) In : Annals of Surgical Oncology. p. 1-5 5 p.

Research output: Research - peer-reviewArticle

Melanoma
Tomography
Recurrence
Neoplasms
Skin

The authors reply

Rosenberg, S. A., Tran, E. & Robbins, P. F. Feb 16 2017 In : New England Journal of Medicine. 376, 7, p. e11

Research output: Research - peer-reviewLetter

Treatment of metastatic uveal melanoma with adoptive transfer of tumour-infiltrating lymphocytes: A single-centre, two-stage, single-arm, phase 2 study

Chandran, S. S., Somerville, R. P. T., Yang, J. C., Sherry, R. M., Klebanoff, C. A., Goff, S. L., Wunderlich, J. R., Danforth, D. N., Zlott, D., Paria, B. C., Sabesan, A. C., Srivastava, A. K., Xi, L., Pham, T. H., Raffeld, M., White, D. E., Toomey, M. A., Rosenberg, S. A. & Kammula, U. S. 2017 (Accepted/In press) In : The Lancet Oncology.

Research output: Research - peer-reviewArticle

Tumor-Infiltrating Lymphocytes
Adoptive Transfer
Therapeutics
Uveal melanoma
Neoplasms

Treatment of patients with metastatic cancer using a major histocompatibility complex class II-restricted T-cell receptor targeting the cancer germline antigen MAGE-A3

Lu, Y. C., Parker, L. L., Lu, T., Zheng, Z., Toomey, M. A., White, D. E., Yao, X., Li, Y. F., Robbins, P. F., Feldman, S. A., Van Der Bruggen, P., Klebanoff, C. A., Goff, S. L., Sherry, R. M., Kammula, U. S., Yang, J. C. & Rosenberg, S. A. Oct 10 2017 In : Journal of Clinical Oncology. 35, 29, p. 3322-3329 8 p.

Research output: Research - peer-reviewArticle

Melanoma-Specific Antigens
T-Cell Antigen Receptor
Major Histocompatibility Complex
Antigens
Neoplasms
2016

Adoptive T-Cell Therapy for Cancer

Yang, J. C. & Rosenberg, S. A. 2016 (Accepted/In press) In : Advances in Immunology.

Research output: Research - peer-reviewArticle

Cell- and Tissue-Based Therapy
T-Lymphocytes
Neoplasms
Immunotherapy
Antigens
Wilms' Tumor Genes
Wilms Tumor
T-Cell Antigen Receptor
Antigens
Peptides

Allogeneic T cells that express an anti-CD19 chimeric antigen receptor induce remissions of B-cell malignancies that progress after allogeneic hematopoietic stem-cell transplantation without causing graft-versus-host disease

Brudno, J. N. , Somerville, R. P. T. , Shi, V. , Rose, J. J. , Halverson, D. C. , Fowler, D. H. , Gea-Banacloche, J. C. , Pavletic, S. Z. , Hickstein, D. D. , Lu, T. L. , Feldman, S. A. , Iwamoto, A. T. , Kurlander, R. , Maric, I. , Goy, A. , Hansen, B. G. , Wilder, J. S. , Blacklock-Schuver, B. , Hakim, F. T. , Rosenberg, S. A. & 2 others Gress, R. E. & Kochenderfer, J. N. Apr 1 2016 In : Journal of Clinical Oncology. 34, 10, p. 1112-1121 10 p.

Research output: Research - peer-reviewArticle

CD19 Antigens
Antigen Receptors
Hematopoietic Stem Cell Transplantation
Graft vs Host Disease
T-Cell Antigen Receptor

A Rapid Cell Expansion Process for Production of Engineered Autologous CAR-T Cell Therapies

Lu, T. L., Pugach, O., Somerville, R., Rosenberg, S. A., Kochendefer, J. N., Better, M. & Feldman, S. A. Dec 1 2016 In : Human gene therapy methods. 27, 6, p. 209-218 10 p.

Research output: Research - peer-reviewArticle

Cell- and Tissue-Based Therapy
T-Lymphocytes
CD19 Antigens
Antigen Receptors
Clinical Trials

Circulating tumor DNA as an early indicator of response to T-cell transfer immunotherapy in metastatic melanoma

Xi, L., Pham, T. H. T., Payabyab, E. C., Sherry, R. M., Rosenberg, S. A. & Raffeld, M. Nov 15 2016 In : Clinical Cancer Research. 22, 22, p. 5480-5486 7 p.

Research output: Research - peer-reviewArticle

Immunotherapy
Melanoma
T-Lymphocytes
DNA
Neoplasms

Durable complete response from metastatic melanoma after transfer of autologous T cells recognizing 10 mutated tumor antigens

Prickett, T. D., Crystal, J. S., Cohen, C. J., Pasetto, A., Parkhurst, M. R., Gartner, J. J., Yao, X., Wang, R., Gros, A., Li, Y. F., El-Gamil, M., Trebska-McGowan, K., Rosenberg, S. A. & Robbins, P. F. 2016 In : Cancer immunology research. 4, 8, p. 669-678 10 p.

Research output: Research - peer-reviewArticle

Neoplasm Antigens
Melanoma
T-Lymphocytes
Neoplasms
Therapeutics

Expression of MAGE-A and NY-ESO-1 in Primary and Metastatic Cancers

Park, T. S., Groh, E. M., Patel, K., Kerkar, S. P., Lee, C. C. R. & Rosenberg, S. A. Jan 1 2016 In : Journal of Immunotherapy. 39, 1, p. 1-7 7 p.

Research output: Research - peer-reviewArticle

Melanoma-Specific Antigens
Squamous Cell Neoplasms
Esophageal Neoplasms
Neoplasms
Melanoma

Isolation and characterization of an HLA-DPB1∗04: 01-restricted MAGE-A3 T-cell receptor for cancer immunotherapy

Yao, X., Lu, Y. C., Parker, L. L., Li, Y. F., El-Gamil, M., Black, M. A., Xu, H., Feldman, S. A., Van Der Bruggen, P., Rosenberg, S. A. & Robbins, P. F. 2016 In : Journal of Immunotherapy. 39, 5, p. 191-201 11 p.

Research output: Research - peer-reviewArticle

T-Cell Antigen Receptor
Immunotherapy
Neoplasms
HLA-DPB1 antigen
T-Lymphocytes

MAGE-A is more highly expressed than NY-ESO-1 in a systematic immunohistochemical analysis of 3668 cases

Kerkar, S. P., Wang, Z. F., Lasota, J., Park, T., Patel, K., Groh, E., Rosenberg, S. A. & Miettinen, M. M. 2016 In : Journal of Immunotherapy. 39, 4, p. 181-187 7 p.

Research output: Research - peer-reviewArticle

Melanoma-Specific Antigens
Esophageal Squamous Cell Carcinoma
Squamous Cell Carcinoma
Carcinoma
Neoplasms

Memory T cell-driven differentiation of naive cells impairs adoptive immunotherapy

Klebanoff, C. A. , Scott, C. D. , Leonardi, A. J. , Yamamoto, T. N. , Cruz, A. C. , Ouyang, C. , Ramaswamy, M. , Roychoudhuri, R. , Ji, Y. , Eil, R. L. , Sukumar, M. , Crompton, J. G. , Palmer, D. C. , Borman, Z. A. , Clever, D. , Thomas, S. K. , Patel, S. , Yu, Z. , Muranski, P. , Liu, H. & 7 others Wang, E., Marincola, F. M., Gros, A., Gattinoni, L., Rosenberg, S. A., Siegel, R. M. & Restifo, N. P. Jan 4 2016 In : Journal of Clinical Investigation. 126, 1, p. 318-334 17 p.

Research output: Research - peer-reviewArticle

Adoptive Immunotherapy
Cell Differentiation
T-Lymphocytes
Adoptive Transfer
T-Lymphocyte Subsets

Metastasectomy Following Immunotherapy with Adoptive Cell Transfer for Patients with Advanced Melanoma

Klemen, N. D., Feingold, P. L., Goff, S. L., Hughes, M. S., Kammula, U. S., Yang, J. C., Schrump, D. S., Rosenberg, S. A. & Sherry, R. M. Sep 16 2016 (Accepted/In press) In : Annals of Surgical Oncology. p. 1-7 7 p.

Research output: Research - peer-reviewArticle

Metastasectomy
Adoptive Transfer
Immunotherapy
Melanoma
Disease-Free Survival

Prospective identification of neoantigen-specific lymphocytes in the peripheral blood of melanoma patients

Gros, A., Parkhurst, M. R., Tran, E., Pasetto, A., Robbins, P. F., Ilyas, S., Prickett, T. D., Gartner, J. J., Crystal, J. S., Roberts, I. M., Trebska-McGowan, K., Wunderlich, J. R., Yang, J. C. & Rosenberg, S. A. Feb 22 2016 (Accepted/In press) In : Nature Medicine.

Research output: Research - peer-reviewArticle

Melanoma
Lymphocytes
Blood
Neoplasms
Tumors

Prospects for gene-engineered T cell immunotherapy for solid cancers

Klebanoff, C. A., Rosenberg, S. A. & Restifo, N. P. Jan 6 2016 In : Nature Medicine. 22, 1, p. 26-36 11 p.

Research output: Research - peer-reviewArticle

T-cells
T-Cell Antigen Receptor
Tumors
Genes
Antigens

Randomized, prospective evaluation comparing intensity of lymphodepletion before adoptive transfer of tumor-infiltrating lymphocytes for patients with metastatic melanoma

Goff, S. L. , Dudley, M. E. , Citrin, D. E. , Somerville, R. P. , Wunderlich, J. R. , Danforth, D. N. , Zlott, D. A. , Yang, J. C. , Sherry, R. M. , Kammula, U. S. , Klebanoff, C. A. , Hughes, M. S. , Restifo, N. P. , Langhan, M. M. , Shelton, T. E. , Lu, L. , Kwong, M. L. M. , Ilyas, S. , Klemen, N. D. , Payabyab, E. C. & 5 others Morton, K. E., Toomey, M. A., Steinberg, S. M., White, D. E. & Rosenberg, S. A. Jul 10 2016 In : Journal of Clinical Oncology. 34, 20, p. 2389-2397 9 p.

Research output: Research - peer-reviewArticle

Tumor-Infiltrating Lymphocytes
Adoptive Transfer
Melanoma
Whole-Body Irradiation
Survival

Stable, Nonviral Expression of Mutated Tumor Neoantigen-specific T-cell Receptors Using the Sleeping Beauty Transposon/Transposase System

Deniger, D. C., Pasetto, A., Tran, E., Parkhurst, M. R., Cohen, C. J., Robbins, P. F., Cooper, L. J. N. & Rosenberg, S. A. Mar 5 2016 (Accepted/In press) In : Molecular Therapy.

Research output: Research - peer-reviewArticle

Transposases
Beauty
T-Cell Antigen Receptor
T-Lymphocytes
Neoplasms

T-cell transfer therapy targeting mutant KRAS in cancer

Tran, E., Robbins, P. F., Lu, Y. C., Prickett, T. D., Gartner, J. J., Jia, L., Pasetto, A., Zheng, Z., Ray, S., Groh, E. M., Kriley, I. R. & Rosenberg, S. A. Dec 8 2016 In : New England Journal of Medicine. 375, 23, p. 2255-2262 8 p.

Research output: Research - peer-reviewArticle

HLA-C Antigens
Cell- and Tissue-Based Therapy
T-Lymphocytes
Neoplasms
Tumor-Infiltrating Lymphocytes

Tumor- and neoantigen-reactive T-cell receptors can be identified based on their frequency in fresh tumor

Pasetto, A., Gros, A., Robbins, P. F., Deniger, D. C., Prickett, T. D., Matus-Nicodemos, R., Douek, D. C., Howie, B., Robins, H., Parkhurst, M. R., Gartner, J., Trebska-McGowan, K., Crystal, J. S. & Rosenberg, S. A. Sep 1 2016 In : Cancer Immunology Research. 4, 9, p. 734-743 10 p.

Research output: Research - peer-reviewArticle

T-Cell Antigen Receptor
Neoplasms
Neoplasm Antigens
High-Throughput Nucleotide Sequencing
Autoantigens

Use of HLA peptidomics and whole exome sequencing to identify human immunogenic neo-antigens

Kalaora, S., Barnea, E., Merhavi-Shoham, E., Qutob, N., Teer, J. K., Shimony, N., Schachter, J., Rosenberg, S. A., Besser, M. J., Admon, A. & Samuels, Y. 2016 In : Oncotarget. 7, 5, p. 5110-5117 8 p.

Research output: Research - peer-reviewArticle

Exome
HLA Antigens
Antigens
Peptides
Tumor-Infiltrating Lymphocytes
2015

Adoptive Cell rapy - Tumor-Infiltrating Lymphocytes, T-Cell Receptors, and Chimeric Antigen Receptors

Feldman, S. A., Assadipour, Y., Kriley, I., Goff, S. L. & Rosenberg, S. A. Aug 1 2015 In : Seminars in Oncology. 42, 4, p. 626-639 14 p.

Research output: Research - peer-reviewArticle

Adoptive cell transfer as personalized immunotherapy for human cancer

Rosenberg, S. A. & Restifo, N. P. Apr 3 2015 In : Science. 348, 6230, p. 62-68 7 p.

Research output: Research - peer-reviewArticle

Adoptive Transfer
Immunotherapy
Neoplasms
Cell- and Tissue-Based Therapy
Therapeutics

Akt inhibition enhances expansion of potent tumor-specific lymphocytes with memory cell characteristics

Crompton, J. G. , Sukumar, M. , Roychoudhuri, R. , Clever, D. , Gros, A. , Eil, R. L. , Tran, E. , Hanada, K. I. , Yu, Z. , Palmer, D. C. , Kerkar, S. P. , Michalek, R. D. , Upham, T. , Leonardi, A. , Acquavella, N. , Wang, E. , Marincola, F. M. , Gattinoni, L. , Muranski, P. , Sundrud, M. S. & 4 others Klebanoff, C. A., Rosenberg, S. A., Fearon, D. T. & Restifo, N. P. Aug 8 2015 In : Cancer Research. 75, 2, p. 296-305 10 p.

Research output: Research - peer-reviewArticle

Tumor-Infiltrating Lymphocytes
Lymphocytes
Neoplasms
Inhibition (Psychology)
T-Lymphocytes

A pilot trial using lymphocytes genetically engineered with an NY-ESO-1-reactive T-cell receptor: Long-term follow-up and correlates with response

Robbins, P. F., Kassim, S. H., Tran, T. L. N., Crystal, J. S., Morgan, R. A., Feldman, S. A., Yang, J. C., Dudley, M. E., Wunderlich, J. R., Sherry, R. M., Kammula, U. S., Hughes, M. S., Restifo, N. P., Raffeld, M., Lee, C. C. R., Li, Y. F., El-Gamil, M. & Rosenberg, S. A. Mar 1 2015 In : Clinical Cancer Research. 21, 5, p. 1019-1027 9 p.

Research output: Research - peer-reviewArticle

T-Cell Antigen Receptor
Lymphocytes
Melanoma
Synovial Sarcoma
Therapeutics
Second Primary Neoplasms
Molecular Biology
Neoplasms
Research
Genetic Counseling

Cancer immunotherapy

Rosenberg, S. A., Robbins, P. F., Phan, G. Q., Feldman, S. A. & Kochenderfer, J. N. Jan 7 2015 DeVita, Hellman, and Rosenberg's Cancer: Principles & Practice of Oncology: Tenth Edition. Wolters Kluwer Health Adis (ESP)

Research output: ResearchChapter

Anniversaries and Special Events
Immunotherapy
T-Lymphocytes
Pharmaceutical Preparations
Neoplasms

Chemotherapy-refractory diffuse large B-cell lymphoma and indolent B-cell malignancies can be effectively treated with autologous T cells expressing an anti-CD19 chimeric antigen receptor

Kochenderfer, J. N. , Dudley, M. E. , Kassim, S. H. , Somerville, R. P. T. , Carpenter, R. O. , Maryalice, S. S. , Yang, J. C. , Phan, G. Q. , Hughes, M. S. , Sherry, R. M. , Raffeld, M. , Feldman, S. , Lu, L. , Li, Y. F. , Ngo, L. T. , Goy, A. , Feldman, T. , Spaner, D. E. , Wang, M. L. , Chen, C. C. & 6 others Kranick, S. M., Nath, A., Nathan, D. A. N., Morton, K. E., Toomey, M. A. & Rosenberg, S. A. Feb 20 2015 In : Journal of Clinical Oncology. 33, 6, p. 540-549 10 p.

Research output: Research - peer-reviewArticle

CD19 Antigens
Antigen Receptors
B-Cell Lymphoma
B-Lymphocytes
T-Lymphocytes

Clinical Scale Zinc Finger Nuclease-mediated Gene Editing of PD-1 in Tumor Infiltrating Lymphocytes for the Treatment of Metastatic Melanoma

Beane, J. D. , Lee, G. , Zheng, Z. , Mendel, M. , Abate-Daga, D. , Bharathan, M. , Black, M. , Gandhi, N. , Yu, Z. , Chandran, S. , Giedlin, M. , Ando, D. , Miller, J. , Paschon, D. , Guschin, D. , Rebar, E. J. , Reik, A. , Holmes, M. C. , Gregory, P. D. , Restifo, N. P. & 3 others Rosenberg, S. A., Morgan, R. A. & Feldman, S. A. Aug 1 2015 In : Molecular Therapy. 23, 8, p. 1380-1390 11 p.

Research output: Research - peer-reviewArticle

Tumor-Infiltrating Lymphocytes
Zinc Fingers
Melanoma
Cell Death
Therapeutics

Complete regression of metastatic cervical cancer after treatment with human papillomavirus-targeted tumor-infiltrating T cells

Stevanović, S., Draper, L. M., Langhan, M. M., Campbell, T. E., Kwong, M. L., Wunderlich, J. R., Dudley, M. E., Yang, J. C., Sherry, R. M., Kammula, U. S., Restifo, N. P., Rosenberg, S. A. & Hinrichs, C. S. May 10 2015 In : Journal of Clinical Oncology. 33, 14, p. 1543-1550 8 p.

Research output: Research - peer-reviewArticle

Uterine Cervical Neoplasms
T-Lymphocytes
Neoplasms
Therapeutics
Drug Therapy

Cutaneous melanoma

Ribas, A., Slingluff, C. L. & Rosenberg, S. A. Jan 7 2015 DeVita, Hellman, and Rosenberg's Cancer: Principles & Practice of Oncology: Tenth Edition. Wolters Kluwer Health Adis (ESP)

Research output: ResearchChapter

Neoplasms
Therapeutics
Libraries
Health
Early Detection of Cancer

Immunogenicity of somatic mutations in human gastrointestinal cancers

Tran, E., Ahmadzadeh, M., Lu, Y. C., Gros, A., Turcotte, S., Robbins, P. F., Gartner, J. J., Zheng, Z., Li, Y. F., Ray, S., Wunderlich, J. R., Somerville, R. P. & Rosenberg, S. A. Dec 11 2015 In : Science. 350, 6266, p. 1387-1390 4 p.

Research output: Research - peer-reviewArticle

Gastrointestinal Neoplasms
Mutation
Tumor-Infiltrating Lymphocytes
Epitopes
Neoplasms

Immunotherapy: The path to win the war on cancer?

Topalian, S. L., Wolchok, J. D., Chan, T. A., Mellman, I., Palucka, K., Banchereau, J., Rosenberg, S. A. & Wittrup, K. D. Apr 9 2015 In : Cell. 161, 2, p. 185-186 2 p.

Research output: Research - peer-reviewArticle

Isolation of neoantigen-specific T cells from tumor and peripheral lymphocytes

Cohen, C. J., Gartner, J. J., Horovitz-Fried, M., Shamalov, K., Trebska-McGowan, K., Bliskovsky, V. V., Parkhurst, M. R., Ankri, C., Prickett, T. D., Crystal, J. S., Li, Y. F., El-Gamil, M., Rosenberg, S. A. & Robbins, P. F. Oct 1 2015 In : Journal of Clinical Investigation. 125, 10, p. 3981-3991 11 p.

Research output: Research - peer-reviewArticle

Epitopes
Lymphocytes
T-Lymphocytes
Neoplasms
Tumor-Infiltrating Lymphocytes

Novel CD4-based bispecific chimeric antigen receptor designed for enhanced anti-HIV potency and absence of HIV entry receptor activity

Liu, L., Patel, B., Ghanem, M. H., Bundoc, V., Zheng, Z., Morgan, R. A., Rosenberg, S. A., Dey, B. & Berger, E. A. 2015 In : Journal of Virology. 89, 13, p. 6685-6694 10 p.

Research output: Research - peer-reviewArticle

HIV Receptors
Antigen Receptors
HIV
antigens
receptors

Preface

DeVita, V. T., Lawrence, T. S. & Rosenberg, S. A. Jan 7 2015 DeVita, Hellman, and Rosenberg's Cancer: Principles & Practice of Oncology: Tenth Edition. Wolters Kluwer Health Adis (ESP)

Research output: ResearchForeword/postscript

Recurrent inactivating RASA2 mutations in melanoma

Arafeh, R. , Qutob, N. , Emmanuel, R. , Keren-Paz, A. , Madore, J. , Elkahloun, A. , Wilmott, J. S. , Gartner, J. J. , Di Pizio, A. , Winograd-Katz, S. , Sindiri, S. , Rotkopf, R. , Dutton-Regester, K. , Johansson, P. , Pritchard, A. L. , Waddell, N. , Hill, V. K. , Lin, J. C. , Hevroni, Y. , Rosenberg, S. A. & 8 others Khan, J., Ben-Dor, S., Niv, M. Y., Ulitsky, I., Mann, G. J., Scolyer, R. A., Hayward, N. K. & Samuels, Y. Dec 1 2015 In : Nature Genetics. 47, 12, p. 1408-1410 3 p.

Research output: Research - peer-reviewArticle

Melanoma
Mutation
Exome
Tumor Suppressor Genes
Cell Movement

Redistribution, hyperproliferation, activation of natural killer cells and CD8 T cells, and cytokine production during first-in-human clinical trial of recombinant human interleukin-15 in patients with cancer

Conlon, K. C. , Lugli, E. , Welles, H. C. , Rosenberg, S. A. , Fojo, A. T. , Morris, J. C. , Fleisher, T. A. , Dubois, S. P. , Perera, L. P. , Stewart, D. M. , Goldman, C. K. , Bryant, B. R. , Decker, J. M. , Chen, J. , Worthy, T. Y. A. , Figg, W. D. , Peer, C. J. , Sneller, M. C. , Lane, H. C. , Yovandich, J. L. & 3 others Creekmore, S. P., Roederer, M. & Waldmann, T. A. Jan 1 2015 In : Journal of Clinical Oncology. 33, 1, p. 74-82 9 p.

Research output: Research - peer-reviewArticle

Interleukin-15
Natural Killer Cells
Clinical Trials
Cytokines
T-Lymphocytes