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111In- and IRDye800CW-Labeled PLA-PEG Nanoparticle for Imaging Prostate-Specific Membrane Antigen-Expressing Tissues

Banerjee, S. R., Foss, C. A., Horhota, A., Pullambhatla, M., McDonnell, K., Zale, S. & Pomper, M. G. Jan 9 2017 In : Biomacromolecules. 18, 1, p. 201-209 9 p.

Research output: Research - peer-reviewArticle

Antigens
Polyethylene glycols
Tumors
Tissue
Nanoparticles

18F-DCFBC Prostate-Specific Membrane Antigen-Targeted PET/CT Imaging in Localized Prostate Cancer: Correlation with Multiparametric MRI and Histopathology

Turkbey, B., Mena, E., Lindenberg, L., Adler, S., Bednarova, S., Berman, R., Ton, A. T., McKinney, Y., Eclarinal, P., Hill, C., Afari, G., Bhattacharyya, S., Mease, R. C., Merino, M. J., Jacobs, P. M., Wood, B. J., Pinto, P. A., Pomper, M. G. & Choyke, P. L. Oct 1 2017 In : Clinical Nuclear Medicine. 42, 10, p. 735-740 6 p.

Research output: Research - peer-reviewArticle

Prostatic Neoplasms
Neoplasms
human glutamate carboxypeptidase II
Prostatic Hyperplasia
Health Insurance Portability and Accountability Act
Image-Guided Biopsy
Amides
Glioma
Protons
Magnetic Resonance Spectroscopy
Prostatic Neoplasms
Radiotherapy
Observation
Radiation
Therapeutics

A PSMA-targeted theranostic agent for photodynamic therapy

Chen, Y., Chatterjee, S., Lisok, A., Minn, I., Pullambhatla, M., Wharram, B., Wang, Y., Jin, J., Bhujwalla, Z. M., Nimmagadda, S., Mease, R. C. & Pomper, M. G. Feb 1 2017 In : Journal of Photochemistry and Photobiology B: Biology. 167, p. 111-116 6 p.

Research output: Research - peer-reviewArticle

Photochemotherapy
human glutamate carboxypeptidase II
Theranostic Nanomedicine
antigens
therapy

Chemogenetics revealed: DREADD occupancy and activation via converted clozapine

Gomez, J. L., Bonaventura, J., Lesniak, W., Mathews, W. B., Sysa-Shah, P., Rodriguez, L. A., Ellis, R. J., Richie, C. T., Harvey, B. K., Dannals, R. F., Pomper, M. G., Bonci, A. & Michaelides, M. Aug 4 2017 In : Science. 357, 6350, p. 503-507 5 p.

Research output: Research - peer-reviewArticle

Designer Drugs
Clozapine
clozapine N-oxide
Metabolic Activation
Injections

Clinical impact of PSMA-based 18F–DCFBC PET/CT imaging in patients with biochemically recurrent prostate cancer after primary local therapy

Mena, E. , Lindenberg, M. L. , Shih, J. H. , Adler, S. , Harmon, S. , Bergvall, E. , Citrin, D. , Dahut, W. , Ton, A. T. , McKinney, Y. , Weaver, J. , Eclarinal, P. , Forest, A. , Afari, G. , Bhattacharyya, S. , Mease, R. C. , Merino, M. J. , Pinto, P. , Wood, B. J. , Jacobs, P. & 3 others Pomper, M. G., Choyke, P. L. & Turkbey, B. Sep 11 2017 (Accepted/In press) In : European Journal of Nuclear Medicine and Molecular Imaging. p. 1-8 8 p.

Research output: Research - peer-reviewArticle

Prostatic Neoplasms
Therapeutics
Recurrence
Research Ethics Committees
Prostatectomy
Hydrogen
Communication
Peptides
Research
Neoplasms

Defining the clinical utility of PSMA-targeted PET imaging of prostate cancer

Gorin, M. A., Pomper, M. G., Pienta, K. J. & Rowe, S. P. Aug 1 2017 In : BJU International. 120, 2, p. 160-161 2 p.

Research output: Research - peer-reviewEditorial

Development of prostate specific membrane antigen targeted ultrasound microbubbles using bioorthogonal chemistry

Zlitni, A., Yin, M., Janzen, N., Chatterjee, S., Lisok, A., Gabrielson, K. L., Nimmagadda, S., Pomper, M. G., Foster, F. S. & Valliant, J. F. May 1 2017 In : PLoS ONE. 12, 5, 0176958

Research output: Research - peer-reviewArticle

microbubbles
chemistry
antigens
Ultrasonics
human glutamate carboxypeptidase II

High Serum Stability of Collagen Hybridizing Peptides and Their Fluorophore Conjugates

Bennink, L. L., Smith, D. J., Foss, C. A., Pomper, M. G., Li, Y. & Yu, S. M. Jun 5 2017 In : Molecular Pharmaceutics. 14, 6, p. 1906-1915 10 p.

Research output: Research - peer-reviewArticle

Collagen
Peptides
Serum
Pharmacokinetics
glycyl-prolyl-hydroxyproline

Imaging macrophage accumulation in a murine model of chronic pancreatitis with 125I-Iodo-DPA-713 SPECT/CT

Foss, C. A., Liu, L., Mease, R. C., Wang, H., Pasricha, P. & Pomper, M. G. Oct 1 2017 In : Journal of Nuclear Medicine. 58, 10, p. 1685-1690 6 p.

Research output: Research - peer-reviewArticle

Chronic Pancreatitis
Macrophages
Single Photon Emission Computed Tomography Computed Tomography
N,N-diethyl-2-(2-(4-methoxyphenyl)-5,7-dimethyl-pyrazolo(1,5-a)pyrimidin-3-yl)-acetamide
Ceruletide

Imaging of glial cell activation and white matter integrity in brains of active and recently retired national football league players

Coughlin, J. M. , Yuchuanwang, Y. , Minn, I. , Bienko, N. , Ambinder, E. B. , Xu, X. , Peters, M. E. , Dougherty, J. W. , Vranesic, M. , Koo, S. M. , Ahn, H. H. , Lee, M. , Cottrell, C. , Sair, H. I. , Sawa, A. , Munro, C. A. , Nowinski, C. J. , Dannals, R. F. , Lyketsos, C. G. , Kassiou, M. & 5 others Smith, G., Caffo, B., Mori, S., Guilarte, T. R. & Pomper, M. G. Jan 1 2017 In : JAMA Neurology. 74, 1, p. 67-74 8 p.

Research output: Research - peer-reviewArticle

Football
Neuroglia
Brain
White Matter
Proteins

Imaging of Prostate-Specific Membrane Antigen Using [18F]DCFPyL

Rowe, S. P., Gorin, M. A. & Pomper, M. G. 2017 (Accepted/In press) In : PET Clinics.

Research output: Research - peer-reviewArticle

antigens
membranes
human glutamate carboxypeptidase II
cancer
molecules

In vivo stem cell tracking with imageable nanoparticles that bind bioorthogonal chemical receptors on the stem cell surface

Lee, S., Yoon, H. I., Na, J. H., Jeon, S., Lim, S., Koo, H., Han, S. S., Kang, S. W., Park, S. J., Moon, S. H., Park, J. H., Cho, Y. W., Kim, B. S., Kim, S. K., Lee, T., Kim, D., Lee, S., Pomper, M. G., Kwon, I. C. & Kim, K. Sep 1 2017 In : Biomaterials. 139, p. 12-29 18 p.

Research output: Research - peer-reviewArticle

Cell Tracking
Nanoparticles
Stem Cells
Stem cells
Imaging techniques

Low levels of PSMA expression limit the utility of 18F-DCFPyL PET/CT for imaging urothelial carcinoma

Campbell, S. P., Baras, A. S., Ball, M. W., Kates, M., Hahn, N. M., Bivalacqua, T. J., Johnson, M. H., Pomper, M. G., Allaf, M. E., Rowe, S. P. & Gorin, M. A. Oct 24 2017 (Accepted/In press) In : Annals of Nuclear Medicine. p. 1-6 6 p.

Research output: Research - peer-reviewArticle

Carcinoma
Prostatic Neoplasms
RNA Sequence Analysis
Renal Cell Carcinoma
Urinary Bladder Neoplasms

Myocardial Blood Flow and Inflammatory Cardiac Sarcoidosis

Kruse, M. J., Kovell, L., Kasper, E. K., Pomper, M. G., Moller, D. R., Solnes, L., Chen, E. S. & Schindler, T. H. Feb 1 2017 In : JACC: Cardiovascular Imaging. 10, 2, p. 157-167 11 p.

Research output: Research - peer-reviewArticle

Sarcoidosis
Inflammation
Perfusion
Positron-Emission Tomography
Therapeutics

Nano-sized metabolic precursors for heterogeneous tumor-targeting strategy using bioorthogonal click chemistry in vivo

Lee, S., Jung, S., Koo, H., Na, J. H., Yoon, H. Y., Shim, M. K., Park, J., Kim, J. H., Lee, S., Pomper, M. G., Kwon, I. C., Ahn, C. H. & Kim, K. Dec 1 2017 In : Biomaterials. 148, p. 1-15 15 p.

Research output: Research - peer-reviewArticle

Click Chemistry
Neoplasms
Tumors
Azides
Cells
Neuroimaging
Systemic Lupus Erythematosus
Positron-Emission Tomography
Proteins
N,N-diethyl-2-(2-(4-methoxyphenyl)-5,7-dimethyl-pyrazolo(1,5-a)pyrimidin-3-yl)-acetamide

Noninvasive Targeted Transcranial Neuromodulation via Focused Ultrasound Gated Drug Release from Nanoemulsions

Airan, R. D., Meyer, R. A., Ellens, N. P. K., Rhodes, K. R., Farahani, K., Pomper, M. G., Kadam, S. D. & Green, J. J. Feb 8 2017 In : Nano Letters. 17, 2, p. 652-659 8 p.

Research output: Research - peer-reviewArticle

Brain
Ultrasonics
Nanoparticles
Pharmaceutical Preparations
seizures

Novel Monoclonal Antibodies Recognizing Human Prostate-Specific Membrane Antigen (PSMA) as Research and Theranostic Tools

Nováková, Z., Foss, C. A., Copeland, B. T., Morath, V., Baranová, P., Havlínová, B., Skerra, A., Pomper, M. G. & Barinka, C. May 15 2017 In : Prostate. 77, 7, p. 749-764 16 p.

Research output: Research - peer-reviewArticle

Monoclonal Antibodies
Research
human glutamate carboxypeptidase II
Theranostic Nanomedicine
Prostatic Neoplasms

Patterns of uptake of prostate-specific membrane antigen (PSMA)-targeted 18F-DCFPyL in peripheral ganglia

Werner, R. A., Sheikhbahaei, S., Jones, K. M., Javadi, M. S., Solnes, L. B., Ross, A. E., Allaf, M. E., Pienta, K. J., Lapa, C., Buck, A. K., Higuchi, T., Pomper, M. G., Gorin, M. A. & Rowe, S. P. Aug 22 2017 (Accepted/In press) In : Annals of Nuclear Medicine. p. 1-7 7 p.

Research output: Research - peer-reviewArticle

Ganglia
human glutamate carboxypeptidase II
Prostatic Neoplasms
Sympathetic Ganglia
Aorta

Pearls and pitfalls in clinical interpretation of prostate-specific membrane antigen (PSMA)-targeted PET imaging

Sheikhbahaei, S., Afshar-Oromieh, A., Eiber, M., Solnes, L. B., Javadi, M. S., Ross, A. E., Pienta, K. J., Allaf, M. E., Haberkorn, U., Pomper, M. G., Gorin, M. A. & Rowe, S. P. Aug 1 2017 (Accepted/In press) In : European Journal of Nuclear Medicine and Molecular Imaging. p. 1-20 20 p.

Research output: Research - peer-reviewArticle

human glutamate carboxypeptidase II
Molecular Imaging
Normal Distribution
Prostatic Neoplasms
Patient Care

PEGylated TRAIL ameliorates experimental inflammatory arthritis by regulation of Th17 cells and regulatory T cells

Park, J. S., Oh, Y., Park, O., Foss, C. A., Lim, S. M., Jo, D. G., Na, D. H., Pomper, M. G., Lee, K. C. & Lee, S. 2017 (Accepted/In press) In : Journal of Controlled Release.

Research output: Research - peer-reviewArticle

TNF-Related Apoptosis-Inducing Ligand
Th17 Cells
Experimental Arthritis
Regulatory T-Lymphocytes
Arthritis

PET-measured longitudinal flow gradient correlates with invasive fractional flow reserve in CAD patients

Valenta, I., Antoniou, A., Marashdeh, W., Leucker, T., Kasper, E., Jones, S. R., Dannals, R. F., Solnes, L., Pomper, M. G. & Schindler, T. H. May 1 2017 In : European Heart Journal Cardiovascular Imaging. 18, 5, p. 538-548 11 p.

Research output: Research - peer-reviewArticle

Coronary Artery Disease
Pathologic Constriction
Perfusion
Ammonia
Myocardium

Prostate Cancer Local Recurrence Detected With Both 18F-Fluciclovine and PSMA-targeted 18F-DCFPyL PET/CT

Gorin, M. A., Pienta, K. J., Pomper, M. G. & Rowe, S. P. 2017 (Accepted/In press) In : Urology.

Research output: Research - peer-reviewArticle

Prostatic Neoplasms
Recurrence
1-amino-3-fluorocyclobutane-1-carboxylic acid
Positron Emission Tomography Computed Tomography
Prostate-Specific Antigen

Prostate-Specific Membrane Antigen–Targeted Imaging With [18F]DCFPyL in High-Grade Gliomas

Salas Fragomeni, R. A., Menke, J. R., Holdhoff, M., Ferrigno, C., Laterra, J. J., Solnes, L. B., Javadi, M. S., Szabo, Z., Pomper, M. G. & Rowe, S. P. Jul 22 2017 (Accepted/In press) In : Clinical Nuclear Medicine.

Research output: Research - peer-reviewArticle

Glioma
2-(3-(1-carboxy-5-((6-fluoropyridine-3-carbonyl)amino)pentyl)ureido)pentanedioic acid
human glutamate carboxypeptidase II
Astrocytoma
Residual Neoplasm

PSMA ligands for PET imaging of prostate cancer

Schwarzenboeck, S. M., Rauscher, I., Bluemel, C., Fendler, W. P., Rowe, S. P., Pomper, M. G., Asfhar-Oromieh, A., Herrmann, K. & Eiber, M. Oct 1 2017 In : Journal of Nuclear Medicine. 58, 10, p. 1545-1552 8 p.

Research output: Research - peer-reviewArticle

Prostatic Neoplasms
Ligands
human glutamate carboxypeptidase II
Standard of Care
Retrospective Studies

Rapid PD-L1 detection in tumors with PET using a highly specific peptide

Chatterjee, S., Lesniak, W. G., Miller, M. S., Lisok, A., Sikorska, E., Wharram, B., Kumar, D., Gabrielson, M., Pomper, M. G., Gabelli, S. B. & Nimmagadda, S. Jan 29 2017 In : Biochemical and Biophysical Research Communications. 483, 1, p. 258-263 6 p.

Research output: Research - peer-reviewArticle

Positron-Emission Tomography
Ligands
Peptides
Neoplasms
Positron emission tomography
Liver
Lacrimal Apparatus
Kidney
Submandibular Gland
Parotid Gland

Structural basis of subunit selectivity for competitive NMDA receptor antagonists with preference for GluN2A over GluN2B subunits

Lind, G. E., Mou, T. C., Tamborini, L., Pomper, M. G., De Micheli, C., Conti, P., Pinto, A. & Hansen, K. B. Aug 15 2017 In : Proceedings of the National Academy of Sciences of the United States of America. 114, 33, p. E6942-E6951

Research output: Research - peer-reviewArticle

N-Methyl-D-Aspartate Receptors
Ligands
Glutamic Acid
Ligand-Gated Ion Channels
Excitatory Amino Acid Antagonists
Allosteric Site
Protein Transport
Binding Sites
Proteins
PK 11195

Translational evaluation of translocator protein as a marker of neuroinflammation in schizophrenia

Notter, T., Coughlin, J. M., Gschwind, T., Weber-Stadlbauer, U., Wang, Y., Kassiou, M., Vernon, A. C., Benke, D., Pomper, M. G., Sawa, A. & Meyer, U. Jan 17 2017 (Accepted/In press) In : Molecular Psychiatry.

Research output: Research - peer-reviewArticle

Schizophrenia
Proteins
Positron-Emission Tomography
Microglia
Cytokines

Uptake of the prostate-specific membrane antigen-targeted PET radiotracer 18F-DCFPyL in elastofibroma dorsi

Gorin, M. A., Mareshdeh, W., Ross, A. E., Allaf, M. E., Pienta, K. J., Pomper, M. G. & Rowe, S. P. Jul 12 2017 (Accepted/In press) In : Nuclear Medicine Communications.

Research output: Research - peer-reviewArticle

Prostatic Neoplasms
human glutamate carboxypeptidase II
2-(3-(1-carboxy-5-((6-fluoropyridine-3-carbonyl)amino)pentyl)ureido)pentanedioic acid
Thoracic Wall
2016

(2S)-2-(3-(1-carboxy-5-(4-211At-astatobenzamido)pentyl) ureido)-pentanedioic acid for PSMA-targeted α-particle radiopharmaceutical therapy

Kiess, A. P., Minn, I., Vaidyanathan, G., Hobbs, R. F., Josefsson, A., Shen, C., Brummet, M., Chen, Y., Choi, J., Koumarianou, E., Baidoo, K., Brechbiel, M. W., Mease, R. C., Sgouros, G., Zalutsky, M. R. & Pomper, M. G. Oct 1 2016 In : Journal of Nuclear Medicine. 57, 10, p. 1569-1575 7 p.

Research output: Research - peer-reviewArticle

Alpha Particles
Radiopharmaceuticals
Acids
Therapeutics
human glutamate carboxypeptidase II

[124I]FIAU: Human dosimetry and infection imaging in patients with suspected prosthetic joint infection

Zhang, X. M., Zhang, H. H., McLeroth, P., Berkowitz, R. D., Mont, M. A., Stabin, M. G., Siegel, B. A., Alavi, A., Barnett, T. M., Gelb, J., Petit, C., Spaltro, J., Cho, S. Y., Pomper, M. G., Conklin, J. J., Bettegowda, C. & Saha, S. May 1 2016 In : Nuclear Medicine and Biology. 43, 5, p. 273-279 7 p.

Research output: Research - peer-reviewArticle

Joints
Infection
fialuridine
Positron Emission Tomography Computed Tomography
Healthy Volunteers

[64Cu]XYIMSR-06: A dual-motif CAIX ligand for PET imaging of clear cell renal cell carcinoma

Minn, I., Koo, S. M., Lee, H. S., Brummet, M., Rowe, S. P., Gorin, M. A., Sysa-Shah, P., Lewis, W. D., Ahn, H. H., Wang, Y., Banerjee, S. R., Mease, R. C., Nimmagadda, S., Allaf, M. E., Pomper, M. G. & Yang, X. 2016 In : Oncotarget. 7, 35, p. 56471-56479 9 p.

Research output: Research - peer-reviewArticle

Renal Cell Carcinoma
Positron-Emission Tomography
Ligands
Neoplasms
Carbonic Anhydrase IX

18F-FNDP for PET Imaging of Soluble Epoxide Hydrolase

Horti, A. G., Wang, Y., Minn, I., Lan, X., Wang, J., Koehler, R. C., Alkayed, N. J., Dannals, R. F. & Pomper, M. G. Nov 1 2016 In : Journal of Nuclear Medicine. 57, 11, p. 1817-1822 6 p.

Research output: Research - peer-reviewArticle

Epoxide Hydrolases
Brain
Papio
Knockout Mice
Radioactivity

A fully human CXCR4 antibody demonstrates diagnostic utility and therapeutic efficacy in solid tumor xenografts

Azad, B. B., Chatterjee, S., Lesniak, W. G., Lisok, A., Pullambhatla, M., Bhujwalla, Z. M., Pomper, M. G. & Nimmagadda, S. Mar 15 2016 In : Oncotarget. 7, 11, p. 12344-12358 15 p.

Research output: Research - peer-reviewArticle

CXCR4 Receptors
Heterografts
Antibodies
Neoplasms
Therapeutics

A humanized antibody for imaging immune checkpoint ligand PD-L1 expression in tumors

Chatterjee, S., Lesniak, W. G., Gabrielson, M., Lisok, A., Wharram, B., Sysa-Shah, P., Azad, B. B., Pomper, M. G. & Nimmagadda, S. 2016 In : Oncotarget. 7, 9, p. 10215-10227 13 p.

Research output: Research - peer-reviewArticle

Antibodies, Monoclonal, Humanized
Ligands
Neoplasms
Heterografts
Antibodies
Pharmacopoeias
Quality Control
human glutamate carboxypeptidase II
Quality control
Specifications

CathepsinB-Specific Metabolic Precursor for InVivo Tumor-Specific Fluorescence Imaging

Shim, M. K., Yoon, H. Y., Ryu, J. H., Koo, H., Lee, S., Park, J. H., Kim, J. H., Lee, S., Pomper, M. G., Kwon, I. C. & Kim, K. 2016 (Accepted/In press) In : Angewandte Chemie - International Edition.

Research output: Research - peer-reviewArticle

Tumors
Fluorescence
Imaging techniques
Cells
Polysaccharides

Characterization of a novel metastatic prostate cancer cell line of LNCaP origin

Castanares, M. A., Copeland, B. T., Chowdhury, W. H., Liu, M. M., Rodriguez, R., Pomper, M. G., Lupold, S. E. & Foss, C. A. Feb 1 2016 In : Prostate. 76, 2, p. 215-225 11 p.

Research output: Research - peer-reviewArticle

Nude Mice
Prostatic Neoplasms
Cell Line
Androgens
Androgen Receptors

Clinical Experience with 18F-Labeled Small Molecule Inhibitors of Prostate-Specific Membrane Antigen

Rowe, S. P., Gorin, M. A., Salas Fragomeni, R. A., Drzezga, A. & Pomper, M. G. 2016 (Accepted/In press) In : PET Clinics.

Research output: Research - peer-reviewArticle

antigens
inhibitors
cancer
membranes
molecules
Castration
Prostatic Neoplasms
Hormones
human glutamate carboxypeptidase II
N-(N-((S)-1,3-Dicarboxypropyl)carbamoyl)-4-(18F)fluorobenzyl-L-cysteine

Computed Tomography Appearance of Renal Hybrid Oncocytic/Chromophobe Tumors

Bhatnagar, A., Rowe, S. P., Gorin, M. A., Pomper, M. G., Fishman, E. K. & Allaf, M. E. Apr 20 2016 (Accepted/In press) In : Journal of Computer Assisted Tomography.

Research output: Research - peer-reviewArticle

Tomography
Kidney
Neoplasms
Oxyphilic Adenoma

Critical Length of PEG Grafts on lPEI/DNA Nanoparticles for Efficient in Vivo Delivery

Williford, J. M., Archang, M. M., Minn, I., Ren, Y., Wo, M., Vandermark, J., Fisher, P. B., Pomper, M. G. & Mao, H. Q. Apr 11 2016 In : ACS Biomaterials Science and Engineering. 2, 4, p. 567-578 12 p.

Research output: Research - peer-reviewArticle

Polyethyleneimine
Grafts
Nanoparticles
DNA
Polyethylene glycols

Design, synthesis and biological evaluation of PSMA/hepsin-targeted heterobivalent ligands

Subedi, M., Minn, I., Chen, J., Kim, Y. H., Ok, K., Jung, Y. W., Pomper, M. G. & Byun, Y. Aug 8 2016 In : European Journal of Medicinal Chemistry. 118, p. 208-218 11 p.

Research output: Research - peer-reviewArticle

Ligands
hepsin
human glutamate carboxypeptidase II
Imaging techniques
Amidines

Detecting Tumor Metastases: The Road to Therapy Starts Here

Menezes, M. E., Das, S. K., Minn, I., Emdad, L., Wang, X. Y., Sarkar, D., Pomper, M. G. & Fisher, P. B. 2016 Advances in Cancer Research. Academic Press Inc., Vol. 132, p. 1-44 44 p. (Advances in Cancer Research; vol. 132)

Research output: ResearchChapter

Neoplasm Metastasis
Neoplasms
Therapeutics
Physiologic Monitoring
Early Diagnosis