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111In- and IRDye800CW-Labeled PLA-PEG Nanoparticle for Imaging Prostate-Specific Membrane Antigen-Expressing Tissues

Banerjee, S. R., Foss, C. A., Horhota, A., Pullambhatla, M., McDonnell, K., Zale, S. & Pomper, M. G. Jan 9 2017 In : Biomacromolecules. 18, 1, p. 201-209 9 p.

Research output: Contribution to journalArticle

Antigens
Polyethylene glycols
Tumors
Tissue
Nanoparticles

18F-DCFBC Prostate-Specific Membrane Antigen-Targeted PET/CT Imaging in Localized Prostate Cancer: Correlation with Multiparametric MRI and Histopathology

Turkbey, B., Mena, E., Lindenberg, L., Adler, S., Bednarova, S., Berman, R., Ton, A. T., McKinney, Y., Eclarinal, P., Hill, C., Afari, G., Bhattacharyya, S., Mease, R. C., Merino, M. J., Jacobs, P. M., Wood, B. J., Pinto, P. A., Pomper, M. G. & Choyke, P. L. Oct 1 2017 In : Clinical Nuclear Medicine. 42, 10, p. 735-740 6 p.

Research output: Contribution to journalArticle

Prostatic Neoplasms
Prostatic Hyperplasia
Neoplasms
Health Insurance Portability and Accountability Act
Neoplasm Grading

A dextran-based probe for the targeted magnetic resonance imaging of tumours expressing prostate-specific membrane antigen

Liu, G., Banerjee, S. R., Yang, X., Yadav, N., Lisok, A., Jablonska, A., Xu, J., Li, Y., Pomper, M. G. & Van Zijl, P. Dec 1 2017 In : Nature Biomedical Engineering. 1, 12, p. 977-982 6 p.

Research output: Contribution to journalArticle

Dextran
Magnetic resonance
Antigens
Dextrans
Tumors
Image-Guided Biopsy
Amides
Glioma
Protons
Magnetic Resonance Spectroscopy
Prostatic Neoplasms
Radiotherapy
Observation
Radiation
Androgens

A PSMA-targeted theranostic agent for photodynamic therapy

Chen, Y., Chatterjee, S., Lisok, A., Minn, I., Pullambhatla, M., Wharram, B., Wang, Y., Jin, J., Bhujwalla, Z. M., Nimmagadda, S., Mease, R. C. & Pomper, M. G. Feb 1 2017 In : Journal of Photochemistry and Photobiology B: Biology. 167, p. 111-116 6 p.

Research output: Contribution to journalArticle

Photochemotherapy
antigens
therapy
membranes
tumors

Cardiosphere-Derived Cells Demonstrate Metabolic Flexibility That Is Influenced by Adhesion Status

Afzal, J., Chan, A., Karakas, M. F., Woldemichael, K., Vakrou, S., Guan, Y., Rathmell, J., Wahl, R., Pomper, M., Foster, D. B., Aon, M. A., Tsui, B., O'Rourke, B. & Abraham, M. R. Oct 1 2017 In : JACC: Basic to Translational Science. 2, 5, p. 543-560 18 p.

Research output: Contribution to journalArticle

Glycolysis
Cell Adhesion
Adenosine Triphosphate
Phosphorylation
Glucose

Chemogenetics revealed: DREADD occupancy and activation via converted clozapine

Gomez, J. L., Bonaventura, J., Lesniak, W., Mathews, W. B., Sysa-Shah, P., Rodriguez, L. A., Ellis, R. J., Richie, C. T., Harvey, B. K., Dannals, R. F., Pomper, M. G., Bonci, A. & Michaelides, M. Aug 4 2017 In : Science. 357, 6350, p. 503-507 5 p.

Research output: Contribution to journalArticle

Designer Drugs
Clozapine
Injections
Technology
Brain

Clinical impact of PSMA-based 18F–DCFBC PET/CT imaging in patients with biochemically recurrent prostate cancer after primary local therapy

Mena, E. , Lindenberg, M. L. , Shih, J. H. , Adler, S. , Harmon, S. , Bergvall, E. , Citrin, D. , Dahut, W. , Ton, A. T. , McKinney, Y. , Weaver, J. , Eclarinal, P. , Forest, A. , Afari, G. , Bhattacharyya, S. , Mease, R. C. , Merino, M. J. , Pinto, P. , Wood, B. J. , Jacobs, P. & 3 others Pomper, M. G., Choyke, P. L. & Turkbey, B. Sep 11 2017 (Accepted/In press) In : European Journal of Nuclear Medicine and Molecular Imaging. p. 1-8 8 p.

Research output: Contribution to journalArticle

Prostatic Neoplasms
Recurrence
Therapeutics
Research Ethics Committees
Prostatectomy
Tumors
Hydrogen
Hydrogen bonds
Communication
Peptides

Defining the clinical utility of PSMA-targeted PET imaging of prostate cancer

Gorin, M. A., Pomper, M. G., Pienta, K. J. & Rowe, S. P. Aug 1 2017 In : BJU International. 120, 2, p. 160-161 2 p.

Research output: Contribution to journalEditorial

Prostatic Neoplasms

Development of prostate specific membrane antigen targeted ultrasound microbubbles using bioorthogonal chemistry

Zlitni, A., Yin, M., Janzen, N., Chatterjee, S., Lisok, A., Gabrielson, K. L., Nimmagadda, S., Pomper, M. G., Foster, F. S. & Valliant, J. F. May 1 2017 In : PLoS ONE. 12, 5, 0176958

Research output: Contribution to journalArticle

microbubbles
Microbubbles
chemistry
Ultrasonics
antigens

High Serum Stability of Collagen Hybridizing Peptides and Their Fluorophore Conjugates

Bennink, L. L., Smith, D. J., Foss, C. A., Pomper, M. G., Li, Y. & Yu, S. M. Jun 5 2017 In : Molecular Pharmaceutics. 14, 6, p. 1906-1915 10 p.

Research output: Contribution to journalArticle

Collagen
Peptides
Serum
glycyl-prolyl-hydroxyproline
Pharmacokinetics

Imaging macrophage accumulation in a murine model of chronic pancreatitis with 125I-Iodo-DPA-713 SPECT/CT

Foss, C. A., Liu, L., Mease, R. C., Wang, H., Pasricha, P. & Pomper, M. G. Oct 1 2017 In : Journal of Nuclear Medicine. 58, 10, p. 1685-1690 6 p.

Research output: Contribution to journalArticle

Chronic Pancreatitis
Macrophages
Ceruletide
Pancreas
Inflammation

Imaging of glial cell activation and white matter integrity in brains of active and recently retired national football league players

Coughlin, J. M. , Yuchuanwang, Y. , Minn, I. , Bienko, N. , Ambinder, E. B. , Xu, X. , Peters, M. E. , Dougherty, J. W. , Vranesic, M. , Koo, S. M. , Ahn, H. H. , Lee, M. , Cottrell, C. , Sair, H. I. , Sawa, A. , Munro, C. A. , Nowinski, C. J. , Dannals, R. F. , Lyketsos, C. G. , Kassiou, M. & 5 others Smith, G., Caffo, B., Mori, S., Guilarte, T. R. & Pomper, M. G. Jan 1 2017 In : JAMA Neurology. 74, 1, p. 67-74 8 p.

Research output: Contribution to journalArticle

Football
Neuroglia
Brain
Athletes
Sports

Imaging of Prostate-Specific Membrane Antigen Using [18F]DCFPyL

Rowe, S. P., Gorin, M. A. & Pomper, M. G. 2017 (Accepted/In press) In : PET Clinics.

Research output: Contribution to journalArticle

antigens
membranes
cancer
Prostatic Neoplasms
Molecular Imaging

In vivo stem cell tracking with imageable nanoparticles that bind bioorthogonal chemical receptors on the stem cell surface

Lee, S., Yoon, H. I., Na, J. H., Jeon, S., Lim, S., Koo, H., Han, S. S., Kang, S. W., Park, S. J., Moon, S. H., Park, J. H., Cho, Y. W., Kim, B. S., Kim, S. K., Lee, T., Kim, D., Lee, S., Pomper, M. G., Kwon, I. C. & Kim, K. Sep 1 2017 In : Biomaterials. 139, p. 12-29 18 p.

Research output: Contribution to journalArticle

Cell Tracking
Stem cells
Nanoparticles
Stem Cells
Glycols

Low levels of PSMA expression limit the utility of 18F-DCFPyL PET/CT for imaging urothelial carcinoma

Campbell, S. P., Baras, A. S., Ball, M. W., Kates, M., Hahn, N. M., Bivalacqua, T. J., Johnson, M. H., Pomper, M. G., Allaf, M. E., Rowe, S. P. & Gorin, M. A. Oct 24 2017 (Accepted/In press) In : Annals of Nuclear Medicine. p. 1-6 6 p.

Research output: Contribution to journalArticle

Carcinoma
RNA Sequence Analysis
Prostatic Neoplasms
Renal Cell Carcinoma
Urinary Bladder Neoplasms

Myocardial Blood Flow and Inflammatory Cardiac Sarcoidosis

Kruse, M. J., Kovell, L., Kasper, E. K., Pomper, M. G., Moller, D. R., Solnes, L., Chen, E. S. & Schindler, T. H. Feb 1 2017 In : JACC: Cardiovascular Imaging. 10, 2, p. 157-167 11 p.

Research output: Contribution to journalArticle

Sarcoidosis
Inflammation
Perfusion
Positron-Emission Tomography
Carbohydrate-Restricted Diet

Nano-sized metabolic precursors for heterogeneous tumor-targeting strategy using bioorthogonal click chemistry in vivo

Lee, S., Jung, S., Koo, H., Na, J. H., Yoon, H. Y., Shim, M. K., Park, J., Kim, J. H., Lee, S., Pomper, M. G., Kwon, I. C., Ahn, C. H. & Kim, K. Dec 1 2017 In : Biomaterials. 148, p. 1-15 15 p.

Research output: Contribution to journalArticle

Click Chemistry
Tumors
Azides
Neoplasms
Bearings (structural)
Neuroimaging
Systemic Lupus Erythematosus
Positron-Emission Tomography
Proteins
Brain

Noninvasive Targeted Transcranial Neuromodulation via Focused Ultrasound Gated Drug Release from Nanoemulsions

Airan, R. D., Meyer, R. A., Ellens, N. P. K., Rhodes, K. R., Farahani, K., Pomper, M. G., Kadam, S. D. & Green, J. J. Feb 8 2017 In : Nano Letters. 17, 2, p. 652-659 8 p.

Research output: Contribution to journalArticle

seizures
Brain
drugs
Ultrasonics
brain damage

Novel Monoclonal Antibodies Recognizing Human Prostate-Specific Membrane Antigen (PSMA) as Research and Theranostic Tools

Nováková, Z., Foss, C. A., Copeland, B. T., Morath, V., Baranová, P., Havlínová, B., Skerra, A., Pomper, M. G. & Barinka, C. May 15 2017 In : Prostate. 77, 7, p. 749-764 16 p.

Research output: Contribution to journalArticle

Monoclonal Antibodies
Research
Prostatic Neoplasms
Heterografts
Epitopes

Patterns of uptake of prostate-specific membrane antigen (PSMA)-targeted 18F-DCFPyL in peripheral ganglia

Werner, R. A., Sheikhbahaei, S., Jones, K. M., Javadi, M. S., Solnes, L. B., Ross, A. E., Allaf, M. E., Pienta, K. J., Lapa, C., Buck, A. K., Higuchi, T., Pomper, M. G., Gorin, M. A. & Rowe, S. P. Aug 22 2017 (Accepted/In press) In : Annals of Nuclear Medicine. p. 1-7 7 p.

Research output: Contribution to journalArticle

Ganglia
Prostatic Neoplasms
Sympathetic Ganglia
Aorta
human glutamate carboxypeptidase II

Pearls and pitfalls in clinical interpretation of prostate-specific membrane antigen (PSMA)-targeted PET imaging

Sheikhbahaei, S., Afshar-Oromieh, A., Eiber, M., Solnes, L. B., Javadi, M. S., Ross, A. E., Pienta, K. J., Allaf, M. E., Haberkorn, U., Pomper, M. G., Gorin, M. A. & Rowe, S. P. Aug 1 2017 (Accepted/In press) In : European Journal of Nuclear Medicine and Molecular Imaging. p. 1-20 20 p.

Research output: Contribution to journalArticle

Molecular Imaging
Normal Distribution
Prostatic Neoplasms
Patient Care
Pathology

PEGylated TRAIL ameliorates experimental inflammatory arthritis by regulation of Th17 cells and regulatory T cells

Park, J. S., Oh, Y., Park, O., Foss, C. A., Lim, S. M., Jo, D. G., Na, D. H., Pomper, M. G., Lee, K. C. & Lee, S. 2017 (Accepted/In press) In : Journal of Controlled Release.

Research output: Contribution to journalArticle

TNF-Related Apoptosis-Inducing Ligand
Th17 Cells
Experimental Arthritis
Regulatory T-Lymphocytes
Arthritis
Coronary Artery Disease
Pathologic Constriction
Perfusion
Ammonia
Myocardium
Prostatic Neoplasms
Recurrence
Prostate-Specific Antigen
1-amino-3-fluorocyclobutane-1-carboxylic acid
Positron Emission Tomography Computed Tomography

Prostate-Specific Membrane Antigen–Targeted Imaging With [18F]DCFPyL in High-Grade Gliomas

Salas Fragomeni, R. A., Menke, J. R., Holdhoff, M., Ferrigno, C., Laterra, J. J., Solnes, L. B., Javadi, M. S., Szabo, Z., Pomper, M. G. & Rowe, S. P. Jul 22 2017 (Accepted/In press) In : Clinical Nuclear Medicine.

Research output: Contribution to journalArticle

Glioma
Astrocytoma
Residual Neoplasm
Glioblastoma
Brain Neoplasms

PSMA ligands for PET imaging of prostate cancer

Schwarzenboeck, S. M., Rauscher, I., Bluemel, C., Fendler, W. P., Rowe, S. P., Pomper, M. G., Asfhar-Oromieh, A., Herrmann, K. & Eiber, M. Oct 1 2017 In : Journal of Nuclear Medicine. 58, 10, p. 1545-1552 8 p.

Research output: Contribution to journalArticle

Prostatic Neoplasms
Ligands
Standard of Care
Retrospective Studies
Neoplasm Metastasis
Positron-Emission Tomography
Prostatic Neoplasms
Information Systems
human glutamate carboxypeptidase II

Rapid PD-L1 detection in tumors with PET using a highly specific peptide

Chatterjee, S., Lesniak, W. G., Miller, M. S., Lisok, A., Sikorska, E., Wharram, B., Kumar, D., Gabrielson, M., Pomper, M. G., Gabelli, S. B. & Nimmagadda, S. Jan 29 2017 In : Biochemical and Biophysical Research Communications. 483, 1, p. 258-263 6 p.

Research output: Contribution to journalArticle

Positron emission tomography
Positron-Emission Tomography
Tumors
Ligands
Peptides
Liver
Lacrimal Apparatus
Submandibular Gland
Parotid Gland
Kidney

Structural basis of subunit selectivity for competitive NMDA receptor antagonists with preference for GluN2A over GluN2B subunits

Lind, G. E., Mou, T. C., Tamborini, L., Pomper, M. G., De Micheli, C., Conti, P., Pinto, A. & Hansen, K. B. Aug 15 2017 In : Proceedings of the National Academy of Sciences of the United States of America. 114, 33, p. E6942-E6951

Research output: Contribution to journalArticle

N-Methyl-D-Aspartate Receptors
Ligands
Glutamic Acid
Ligand-Gated Ion Channels
Excitatory Amino Acid Antagonists
Allosteric Site
Protein Transport
Binding Sites
Genotype
Proteins

Translational evaluation of translocator protein as a marker of neuroinflammation in schizophrenia

Notter, T., Coughlin, J. M., Gschwind, T., Weber-Stadlbauer, U., Wang, Y., Kassiou, M., Vernon, A. C., Benke, D., Pomper, M. G., Sawa, A. & Meyer, U. Jan 17 2017 (Accepted/In press) In : Molecular Psychiatry.

Research output: Contribution to journalArticle

Schizophrenia
Proteins
Positron-Emission Tomography
Microglia
Gliosis

Uptake of the prostate-specific membrane antigen-targeted PET radiotracer 18F-DCFPyL in elastofibroma dorsi

Gorin, M. A., Mareshdeh, W., Ross, A. E., Allaf, M. E., Pienta, K. J., Pomper, M. G. & Rowe, S. P. Jul 12 2017 (Accepted/In press) In : Nuclear Medicine Communications.

Research output: Contribution to journalArticle

Prostatic Neoplasms
Thoracic Wall
human glutamate carboxypeptidase II
2-(3-(1-carboxy-5-((6-fluoropyridine-3-carbonyl)amino)pentyl)ureido)pentanedioic acid
2016

(2S)-2-(3-(1-carboxy-5-(4-211At-astatobenzamido)pentyl) ureido)-pentanedioic acid for PSMA-targeted α-particle radiopharmaceutical therapy

Kiess, A. P., Minn, I., Vaidyanathan, G., Hobbs, R. F., Josefsson, A., Shen, C., Brummet, M., Chen, Y., Choi, J., Koumarianou, E., Baidoo, K., Brechbiel, M. W., Mease, R. C., Sgouros, G., Zalutsky, M. R. & Pomper, M. G. Oct 1 2016 In : Journal of Nuclear Medicine. 57, 10, p. 1569-1575 7 p.

Research output: Contribution to journalArticle

Alpha Particles
Radiopharmaceuticals
Acids
Neoplasm Micrometastasis
Therapeutics

[124I]FIAU: Human dosimetry and infection imaging in patients with suspected prosthetic joint infection

Zhang, X. M., Zhang, H. H., McLeroth, P., Berkowitz, R. D., Mont, M. A., Stabin, M. G., Siegel, B. A., Alavi, A., Barnett, T. M., Gelb, J., Petit, C., Spaltro, J., Cho, S. Y., Pomper, M. G., Conklin, J. J., Bettegowda, C. & Saha, S. May 1 2016 In : Nuclear Medicine and Biology. 43, 5, p. 273-279 7 p.

Research output: Contribution to journalArticle

Joints
Infection
Healthy Volunteers
Thymidine Kinase
Knee Joint

[64Cu]XYIMSR-06: A dual-motif CAIX ligand for PET imaging of clear cell renal cell carcinoma

Minn, I., Koo, S. M., Lee, H. S., Brummet, M., Rowe, S. P., Gorin, M. A., Sysa-Shah, P., Lewis, W. D., Ahn, H. H., Wang, Y., Banerjee, S. R., Mease, R. C., Nimmagadda, S., Allaf, M. E., Pomper, M. G. & Yang, X. 2016 In : Oncotarget. 7, 35, p. 56471-56479 9 p.

Research output: Contribution to journalArticle

Renal Cell Carcinoma
Positron-Emission Tomography
Ligands
Neoplasms
Kidney

18F-FNDP for PET Imaging of Soluble Epoxide Hydrolase

Horti, A. G., Wang, Y., Minn, I., Lan, X., Wang, J., Koehler, R. C., Alkayed, N. J., Dannals, R. F. & Pomper, M. G. Nov 1 2016 In : Journal of Nuclear Medicine. 57, 11, p. 1817-1822 6 p.

Research output: Contribution to journalArticle

Epoxide Hydrolases
Papio
Brain
Knockout Mice
Radioactivity

A fully human CXCR4 antibody demonstrates diagnostic utility and therapeutic efficacy in solid tumor xenografts

Azad, B. B., Chatterjee, S., Lesniak, W. G., Lisok, A., Pullambhatla, M., Bhujwalla, Z. M., Pomper, M. G. & Nimmagadda, S. Mar 15 2016 In : Oncotarget. 7, 11, p. 12344-12358 15 p.

Research output: Contribution to journalArticle

CXCR4 Receptors
Heterografts
Antibodies
Neoplasms
Triple Negative Breast Neoplasms

A humanized antibody for imaging immune checkpoint ligand PD-L1 expression in tumors

Chatterjee, S., Lesniak, W. G., Gabrielson, M., Lisok, A., Wharram, B., Sysa-Shah, P., Azad, B. B., Pomper, M. G. & Nimmagadda, S. 2016 In : Oncotarget. 7, 9, p. 10215-10227 13 p.

Research output: Contribution to journalArticle

Antibodies, Monoclonal, Humanized
Ligands
Neoplasms
Heterografts
Triple Negative Breast Neoplasms
Pharmacopoeias
Quality Control
human glutamate carboxypeptidase II
Quality control
Specifications

CathepsinB-Specific Metabolic Precursor for InVivo Tumor-Specific Fluorescence Imaging

Shim, M. K., Yoon, H. Y., Ryu, J. H., Koo, H., Lee, S., Park, J. H., Kim, J. H., Lee, S., Pomper, M. G., Kwon, I. C. & Kim, K. 2016 (Accepted/In press) In : Angewandte Chemie - International Edition.

Research output: Contribution to journalArticle

Tumors
Fluorescence
Imaging techniques
Cells
Polysaccharides

Characterization of a novel metastatic prostate cancer cell line of LNCaP origin

Castanares, M. A., Copeland, B. T., Chowdhury, W. H., Liu, M. M., Rodriguez, R., Pomper, M. G., Lupold, S. E. & Foss, C. A. Feb 1 2016 In : Prostate. 76, 2, p. 215-225 11 p.

Research output: Contribution to journalArticle

Nude Mice
Prostatic Neoplasms
Androgens
Cell Line
Androgen Receptors

Clinical Experience with 18F-Labeled Small Molecule Inhibitors of Prostate-Specific Membrane Antigen

Rowe, S. P., Gorin, M. A., Salas Fragomeni, R. A., Drzezga, A. & Pomper, M. G. 2016 (Accepted/In press) In : PET Clinics.

Research output: Contribution to journalArticle

antigens
inhibitors
Prostatic Neoplasms
cancer
membranes
Castration
Prostatic Neoplasms
Hormones
Injections
human glutamate carboxypeptidase II
Tomography
Kidney
Neoplasms
Oxyphilic Adenoma
Prostatic Neoplasms
Immunohistochemistry
human glutamate carboxypeptidase II