Find Research Outputs

Search concepts
Selected Filters
2017

A systematic review of emergency department based HIV testing and linkage to care initiatives in low resource settings

Hansoti, B., Kelen, G. D., Quinn, T. C., Whalen, M. M., DesRosiers, T. T., Reynolds, S. J., Redd, A. & Rothman, R., Nov 1 2017, In : PLoS One. 12, 11, e0187443.

Research output: Contribution to journalReview article

systematic review
HIV infections
Hospital Emergency Service
HIV
HIV Infections

Comparison of cross-sectional HIV incidence assay results from dried blood spots and plasma

Schlusser, K. E., Pilcher, C., Kallas, E. G., Santos, B. R., Deeks, S. G., Facente, S., Keating, S. M., Busch, M. P., Murphy, G., Welte, A., Quinn, T. C., Eshleman, S. & Laeyendecker, O. B., Feb 1 2017, In : PLoS One. 12, 2, e0172283.

Research output: Contribution to journalArticle

Assays
Blood
HIV
Plasmas
incidence

Contrasting antibody responses to intrasubtype superinfection with CRF02-AG

Courtney, C. R., Mayr, L., Nanfack, A. J., Banin, A. N., Tuen, M., Pan, R., Jiang, X., Kong, X. P., Kirkpatrick, A. R., Bruno, D., Martens, C. A., Sykora, L., Porcella, S. F., Redd, A., Quinn, T. C., Nyambi, P. N. & Dürr, R., Mar 1 2017, In : PLoS One. 12, 3, e0173705.

Research output: Contribution to journalArticle

Superinfection
Neutralizing Antibodies
Antibody Formation
antibodies
Antibodies

Elevated cytomegalovirus IgG antibody levels are associated with HIV-1 disease progression and immune activation

Patel, E. U., Gianella, S., Newell, K., Tobian, A. A., Kirkpatrick, A. R., Nalugoda, F., Grabowski, M., Gray, R. H., Serwadda, D., Quinn, T. C., Redd, A. & Reynolds, S. J., Jan 24 2017, (Accepted/In press) In : AIDS.

Research output: Contribution to journalArticle

Cytomegalovirus
Disease Progression
HIV-1
Immunoglobulin G
Antibodies

Erratum: Precision of the Kalon Herpes Simplex Virus Type 2 IgG ELISA: An international inter-laboratory assessment [BMC Infect Dis. 15, (2015)(398)] DOI: 10.1186/s12879-015-1130-6

Patel, E. U., Manucci, J., Kahle, E. M., Lingappa, J. R., Morrow, R. A., Piwowar-Manning, E., James, A., Maluzi, K. F., Cheeba, M. M., Gray, G., Kosloff, B., Delany-Moretlwe, S., Inambao, M., Vwalika, B., Quinn, T. C. & Laeyendecker, O. B., May 19 2017, In : BMC Infectious Diseases. 17, 1, 355.

Research output: Contribution to journalComment/debate

Human Herpesvirus 2
Immunoglobulin G
Enzyme-Linked Immunosorbent Assay
Tropical Medicine
Zambia

Finding youths at risk for HIV infection: Targeted Testing, universal testing, or both?

Agwu, A. L. & Quinn, T. C., Jun 1 2017, In : JAMA Pediatrics. 171, 6, p. 517-518 2 p.

Research output: Contribution to journalEditorial

HIV Infections

HIV-1 Full-Genome Phylogenetics of Generalized Epidemics in Sub-Saharan Africa: Impact of Missing Nucleotide Characters in Next-Generation Sequences

Ratmann, O., Wymant, C., Colijn, C., Danaviah, S., Essex, M., Frost, S., Gall, A., Gaseitsiwe, S., Grabowski, M., Gray, R. H., Guindon, S., Von Haeseler, A., Kaleebu, P., Kendall, M., Kozlov, A., Manasa, J., Minh, B. Q., Moyo, S., Novitsky, V., Nsubuga, R. & 12 othersPillay, S., Quinn, T. C., Serwadda, D., Ssemwanga, D., Stamatakis, A., Trifinopoulos, J., Wawer, M. J., Brown, A. L., De Oliveira, T., Kellam, P., Pillay, D. & Fraser, C., Nov 1 2017, In : AIDS Research and Human Retroviruses. 33, 11, p. 1083-1098 16 p.

Research output: Contribution to journalArticle

Africa South of the Sahara
HIV-1
Nucleotides
HIV
Genome

HIV-1 superinfection can occur in the presence of broadly neutralizing antibodies

Serwanga, J., Ssemwanga, D., Muganga, M., Nakiboneka, R., Nakubulwa, S., Kiwuwa-Muyingo, S., Morris, L., Redd, A., Quinn, T. C. & Kaleebu, P., Jan 1 2017, (Accepted/In press) In : Vaccine.

Research output: Contribution to journalArticle

Superinfection
Human immunodeficiency virus 1
Neutralizing Antibodies
neutralizing antibodies
HIV-1

HIV prevention efforts and incidence of HIV in Uganda

Grabowski, M., Serwadda, D. M., Gray, R. H., Nakigozi, G., Kigozi, G., Kagaayi, J., Ssekubugu, R., Nalugoda, F., Lessler, J. T., Lutalo, T., Galiwango, R. M., Makumbi, F., Kong, X., Kabatesi, D., Alamo, S. T., Wiersma, S., Sewankambo, N. K., Tobian, A. A., Laeyendecker, O. B., Quinn, T. C. & 3 othersReynolds, S. J., Wawer, M. J. & Chang, L., Nov 30 2017, In : New England Journal of Medicine. 377, 22, p. 2154-2166 13 p.

Research output: Contribution to journalArticle

Uganda
HIV
Incidence
Virus Diseases
Male Circumcision

HIV viral load monitoring among key populations in low- and middle-income countries: Challenges and opportunities: Challenges

Schwartz, S., Kavanagh, M. M., Sugarman, J., Solomon, S., Njindam, I. M., Rebe, K., Quinn, T. C., Toure-Kane, C., Beyrer, C. & Baral, S., Nov 1 2017, In : Journal of the International AIDS Society. 20, p. 43-49 7 p.

Research output: Contribution to journalArticle

Viral Load
HIV
Population
Program Evaluation
Sex Work
Uganda
Randomized Controlled Trials
HIV
Health
Therapeutics

Low rates of transmitted drug resistance among newly identified HIV-1 seroconverters in Rural Rakai, Uganda

Reynolds, S. J., Ssempijja, V., Galiwango, R., Ndyanabo, A., Nakigozi, G., Lyagoba, F., Nazziwa, J., Redd, A., Lamers, S. L., Gray, R. H., Wawer, M. J., Serwadda, D. & Quinn, T. C., May 1 2017, In : AIDS Research and Human Retroviruses. 33, 5, p. 448-451 4 p.

Research output: Contribution to journalArticle

Uganda
Drug Resistance
HIV-1
Mutation
Reverse Transcriptase Inhibitors
Chlamydia trachomatis
Inflammation
Trachoma
Infection
Chlamydia Infections

Multimethod longitudinal HIV drug resistance analysis in antiretroviral-therapy-naive patients

Nanfack, A. J., Redd, A., Bimela, J. S., Ncham, G., Achem, E., Banin, A. N., Kirkpatrick, A. R., Porcella, S. F., Agyingi, L. A., Meli, J., Colizzi, V., Nádas, A., Gorny, M. K., Nyambi, P. N., Quinn, T. C. & Duerra, R., Sep 1 2017, In : Journal of Clinical Microbiology. 55, 9, p. 2785-2800 16 p.

Research output: Contribution to journalArticle

Drug Resistance
HIV
Mutation
Therapeutics
Cameroon

Patient and provider attitudes to emergency department-based HIV counselling and testing in South Africa

Hansoti, B., Hill, S. E., Whalen, M., Stead, D., Parrish, A., Rothman, R., Hsieh, Y-H. & Quinn, T. C., 2017, In : Southern African Journal of HIV Medicine. 18, 1, a707.

Research output: Contribution to journalArticle

South Africa
Hospital Emergency Service
Counseling
HIV
Privacy

Penile Immune Activation and Risk of HIV Shedding: A Prospective Cohort Study

Patel, E. U., Kirkpatrick, A. R., Grabowski, M., Kigozi, G., Gray, R. H., Prodger, J., Redd, A., Nalugoda, F., Serwadda, D., Wawer, M. J., Quinn, T. C. & Tobian, A. A., Mar 15 2017, In : Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 64, 6, p. 776-784 9 p.

Research output: Contribution to journalArticle

Virus Shedding
Cohort Studies
HIV
Prospective Studies
Odds Ratio

Reduced frequency of cells latently infected with replication-competent human immunodeficiency virus-1 in virally suppressed individuals living in Rakai, Uganda

Prodger, J., Lai, J., Reynolds, S. J., Keruly, J. C., Moore, R. D., Kasule, J., Kityamuweesi, T., Buule, P., Serwadda, D., Nason, M., Capoferri, A. A., Porcella, S. F., Siliciano, R. F., Redd, A., Siliciano, J. M. & Quinn, T. C., Oct 1 2017, In : Clinical Infectious Diseases. 65, 8, p. 1308-1315 8 p.

Research output: Contribution to journalArticle

Uganda
HIV-1
T-Lymphocytes
Baltimore
Virus Diseases
Hepacivirus
India
HIV
Pharmaceutical Preparations
Costs and Cost Analysis

Short Communication: False Recent Ratio of the Limiting-Antigen Avidity Assay and Viral Load Testing Algorithm among Cameroonians with Long-Term HIV Infection

Lynch, B. A., Patel, E. U., Courtney, C. R., Nanfack, A. J., Bimela, J., Wang, X., Eid, I., Quinn, T. C., Laeyendecker, O. B., Nyambi, P. N., Duerr, R. & Redd, A., Nov 1 2017, In : AIDS Research and Human Retroviruses. 33, 11, p. 1114-1116 3 p.

Research output: Contribution to journalArticle

Viral Load
HIV Infections
Central Africa
Antigens
Incidence
Immunoenzyme Techniques
HIV Infections
Antigens
Therapeutics
Viral Load

Treating village newcomers and travelers for trachoma: Results from ASANTE cluster randomized trial

West, S. K., Munoz, B., Mkocha, H., Dize, L., Gaydos, C. A., Swenor, B., Ervin, A. M. & Quinn, T. C., Jun 1 2017, In : PLoS One. 12, 6, e0178595.

Research output: Contribution to journalArticle

Trachoma
villages
infection
Infection
monitoring
Uganda
Heterosexuality
HIV
Genotype
Male Circumcision

Weak HIV Antibody Responses in Perinatally-Infected Young Adults

Kirkpatrick, A. R., Unsal, A. B., Blankson, J. N., Moore, R. D., Quinn, T. C., Hadigan, C. & Laeyendecker, O. B., Jun 23 2017, (Accepted/In press) In : Pediatric Infectious Disease Journal.

Research output: Contribution to journalArticle

HIV Antibodies
Antibody Formation
Young Adult
HIV
Incidence
2016

Association of medical male circumcision and antiretroviral therapyscale-up with community HIV incidence in Rakai, Uganda

Kong, X., Kigozi, G., Ssekasanvu, J., Nalugoda, F., Nakigozi, G., Ndyanabo, A., Lutalo, T., Reynolds, S. J., Ssekubugu, R., Kagaayi, J., Bugos, E., Chang, L., Nanlesta, P., Grabowski, M., Berman, A., Quinn, T. C., Serwadda, D., Wawer, M. J. & Gray, R. H., Jul 12 2016, In : JAMA - Journal of the American Medical Association. 316, 2, p. 182-190 9 p.

Research output: Contribution to journalArticle

Male Circumcision
Uganda
HIV
Incidence
Therapeutics

A transmission-virulence evolutionary trade-off explains attenuation of HIV-1 in uganda

Blanquart, F., Grabowski, M., Herbeck, J., Nalugoda, F., Serwadda, D., Eller, M. A., Robb, M. L., Gray, R. H., Kigozi, G., Laeyendecker, O. B., Lythgoe, K. A., Nakigozi, G., Quinn, T. C., Reynolds, S. J., Wawer, M. J. & Fraser, C., Nov 5 2016, In : eLife. 5, NOVEMBER2016, e20492.

Research output: Contribution to journalArticle

Uganda
Virulence
HIV-1
Pathogens
Viral Load
Trachoma
Chlamydia trachomatis
Antibodies
Surveys and Questionnaires

Detection of acute and early HIV-1 infections in an HIV hyper-endemic area with limited resources

Mayaphi, S. H., Martin, D. J., Quinn, T. C., Laeyendecker, O. B., Olorunju, S. A. S., Tintinger, G. R. & Stoltz, A. C., Oct 1 2016, In : PLoS One. 11, 10, e0164943.

Research output: Contribution to journalArticle

HIV infections
Human immunodeficiency virus 1
HIV Infections
HIV-1
HIV
Immunoenzyme Techniques
HIV
Incidence
Population
Infection

Evaluation of hidden HIV infections in an urban ED with a rapid HIV screening program

Hsieh, Y-H., Kelen, G. D., Beck, K. J., Kraus, C. K., Shahan, J. B., Laeyendecker, O. B., Quinn, T. C. & Rothman, R., Feb 1 2016, In : American Journal of Emergency Medicine. 34, 2, p. 180-184 5 p.

Research output: Contribution to journalArticle

HIV Infections
Hospital Emergency Service
HIV
Serum
Self Report
Centers for Disease Control and Prevention (U.S.)
Hepacivirus
Hospital Emergency Service
Virus Diseases
Parturition

Heterogeneity of the HIV epidemic in agrarian, trading, and fishing communities in Rakai, Uganda: an observational epidemiological study

Chang, L., Grabowski, M., Ssekubugu, R., Nalugoda, F., Kigozi, G., Nantume, B., Lessler, J. T., Moore, S. M., Quinn, T. C., Reynolds, S. J., Gray, R. H., Serwadda, D. & Wawer, M. J., Aug 1 2016, In : The Lancet HIV. 3, 8, p. e388-e396

Research output: Contribution to journalArticle

Uganda
Observational Studies
Epidemiologic Studies
HIV
National Institute of Allergy and Infectious Diseases (U.S.)

Immunological signaling during herpes simplex virus-2 and cytomegalovirus vaginal shedding after initiation of antiretroviral treatment

Nason, M. C., Patel, E. U., Kirkpatrick, A. R., Prodger, J., Shahabi, K., Tobian, A. A., Gianella, S., Kalibbala, S., Ssebbowa, P., Kaul, R., Gray, R. H., Quinn, T. C., Serwadda, D., Reynolds, S. J. & Redd, A., Apr 1 2016, In : Open Forum Infectious Diseases. 3, 2, ofw073.

Research output: Contribution to journalComment/debate

Human Herpesvirus 2
Cytomegalovirus
Interleukin-6
Virus Shedding
Cytokines

Improvements in the continuum of HIV care in an inner-city emergency department

Kelen, G. D., Hsieh, Y-H., Rothman, R., Patel, E. U., Laeyendecker, O. B., Marzinke, M. A., Clarke, W., Parsons, T., Manucci, J. L. & Quinn, T. C., Jan 2 2016, In : AIDS. 30, 1, p. 113-120 8 p.

Research output: Contribution to journalArticle

Continuity of Patient Care
Hospital Emergency Service
HIV
Hospital Departments
Baltimore

Longitudinal household surveillance for malaria in Rakai, Uganda

Newell, K., Kiggundu, V., Ouma, J., Baghendage, E., Kiwanuka, N., Gray, R. H., Serwadda, D., Hobbs, C. V., Healy, S. A., Quinn, T. C. & Reynolds, S. J., Feb 9 2016, In : Malaria Journal. 15, 1, 1128.

Research output: Contribution to journalArticle

Uganda
Malaria
Parasitemia
Caregivers
HIV
Human Herpesvirus 2
antineoplaston A10
Virus Diseases
Hepacivirus
Hospital Emergency Service

Partner Human Papillomavirus Viral Load and Incident Human Papillomavirus Detection in Heterosexual Couples

Grabowski, M., Kong, X., Gray, R. H., Serwadda, D., Kigozi, G., Gravitt, P. E., Nalugoda, F., Reynolds, S. J., Wawer, M. J., Redd, A., Watya, S., Quinn, T. C. & Tobian, A. A., Mar 15 2016, In : Journal of Infectious Diseases. 213, 6, p. 948-956 9 p.

Research output: Contribution to journalArticle

Heterosexuality
Viral Load
Genotype
Confidence Intervals
Male Circumcision
Azithromycin
Trachoma
Chlamydia trachomatis
Inflammation
Chlamydia Infections

Treatment as Prevention: Characterization of partner infections in the HIV Prevention Trials Network 052 trial

Eshleman, S., Hudelson, S. E., Redd, A., Swanstrom, R., Ou, S. S., Zhang, X. C., Ping, L. H., Piwowar-Manning, E., Porcella, S. F., Sievers, M. F., Martens, C. A., Bruno, D., Dukhovlinova, E., McCauley, M., Gamble, T., Fogel, J. M. L., Sabin, D., Quinn, T. C., Gunde, L., Maliwichi, M. & 13 othersNhando, N., Akelo, V., Moyo, S., Panchia, R., Kumarasamy, N., Chotirosniramit, N., Gonçalves de Melo, M., Pilotto, J., Grinsztejn, B., Mayer, K., Chen, Y. Q., Hughes, J. P. & Cohen, M. S., Aug 16 2016, (Accepted/In press) In : Journal of Acquired Immune Deficiency Syndromes.

Research output: Contribution to journalArticle

HIV Infections
Infection
HIV
Therapeutics
Genetic Linkage

Use of Hepatitis C Virus (HCV) Immunoglobulin G Antibody Avidity as a Biomarker to Estimate the Population-Level Incidence of HCV Infection

Patel, E. U., Cox, A., Mehta, S. H., Boon, D., Mullis, C. E., Astemborski, J., Osburn, W., Quinn, J., Redd, A., Kirk, G. D., Thomas, D. L., Quinn, T. C. & Laeyendecker, O. B., Aug 1 2016, In : Journal of Infectious Diseases. 214, 3, p. 344-352 9 p.

Research output: Contribution to journalArticle

Antibody Affinity
Virus Diseases
Hepacivirus
Immunoglobulin G
Biomarkers

Using nearly full-genome HIV sequence data improves phylogeny reconstruction in a simulated epidemic

PANGEA-HIV Consortium & ICONIC Project, Dec 23 2016, In : Scientific Reports. 6, 39489.

Research output: Contribution to journalArticle

Phylogeny
HIV
Genome
pol Genes
gag Genes
2015

Antibody maturation in women who acquire HIV infection while using antiretroviral preexposure prophylaxis

Laeyendecker, O. B., Redd, A., Nason, M., Longosz, A. F., Karim, Q. A., Naranbhai, V., Garrett, N., Eshleman, S., Abdool Karim, S. S. & Quinn, T. C., 2015, In : Journal of Infectious Diseases. 212, 5, p. 754-759 6 p.

Research output: Contribution to journalArticle

Tenofovir
Virus Diseases
HIV
Antibodies
Antibody Affinity

Burden of hepatitis C virus disease and access to hepatitis C virus services in people who inject drugs in India: A cross-sectional study

Solomon, S., Mehta, S. H., Srikrishnan, A. K., Solomon, S., McFall, A. M., Laeyendecker, O. B., Celentano, D. D., Iqbal, S. H., Anand, S., Vasudevan, C. K., Saravanan, S., Lucas, G. M., Kumar, M. S., Sulkowski, M. & Quinn, T. C., Jan 1 2015, In : Lancet Infectious Diseases. 15, 1, p. 36-45 10 p.

Research output: Contribution to journalArticle

Virus Diseases
Hepacivirus
India
Cross-Sectional Studies
Pharmaceutical Preparations

Comparison of antibody responses to HIV infection in ugandan women infected with HIV subtypes A and D

Longosz, A. F., Morrison, C. S., Chen, P. L., Brand, H. H., Arts, E., Nankya, I., Salata, R. A., Quinn, T. C., Eshleman, S. & Laeyendecker, O. B., Apr 1 2015, In : AIDS Research and Human Retroviruses. 31, 4, p. 421-427 7 p.

Research output: Contribution to journalArticle

HIV Infections
Antibody Formation
HIV
Infection
Antigens

Decreased monocyte activation with daily acyclovir use in HIV-1/HSV-2 coinfected women

Redd, A., Newell, K., Patel, E. U., Nalugoda, F., Ssebbowa, P., Kalibbala, S., Frank, M. A., Tobian, A. A., Gray, R. H., Quinn, T. C., Serwadda, D. & Reynolds, S. J., Nov 1 2015, In : Sexually Transmitted Infections. 91, 7, p. 485-488 4 p.

Research output: Contribution to journalArticle

Human Herpesvirus 2
Acyclovir
HIV-1
Monocytes
Viral Load

Differential associations of IL-6 and intestinal fatty acid-binding protein with progressive untreated HIV-1 infection in Rakai, Uganda

Olwenyi, O. A., Naluyima, P., Cham, F., Quinn, T. C., Serwadda, D., Sewankambo, N. K., Gray, R. H., Sandberg, J. K., Michael, N. L., Wabwire-Mangen, F., Robb, M. L. & Eller, M. A., Dec 1 2015, (Accepted/In press) In : Journal of Acquired Immune Deficiency Syndromes.

Research output: Contribution to journalArticle

Fatty Acid-Binding Proteins
Uganda
HIV Infections
HIV-1
Interleukin-6

Durable suppression of HIV-1 after virologic monitoring-based antiretroviral adherence counseling in rakai, Uganda

Billioux, A., Nakigozi, G., Newell, K., Chang, L., Quinn, T. C., Gray, R. H., Ndyanabo, A., Galiwango, R., Kiggundu, V., Serwadda, D. & Reynolds, S. J., May 1 2015, In : PLoS One. 10, 5, e0127235.

Research output: Contribution to journalArticle

Uganda
counseling
viral load
Human immunodeficiency virus 1
Viral Load
Preventive Medicine
Uganda
Sulfamethoxazole Drug Combination Trimethoprim
HIV
House Calls

Evaluation of postpartum HIV superinfection and mother-to-child transmission

Redd, A., Wendel, S. K. J., Longosz, A. F., Fogel, J. M. L., Dadabhai, S., Kumwenda, N., Sun, J., Walker, M. P., Bruno, D., Martens, C., Eshleman, S., Porcella, S. F., Quinn, T. C. & Tahac, T. E., Jul 31 2015, In : AIDS. 29, 12, p. 1567-1573 7 p.

Research output: Contribution to journalArticle

Superinfection
Postpartum Period
Mothers
HIV
Post-Exposure Prophylaxis

Genome sequencing and analysis of geographically diverse clinical isolates of herpes simplex virus 2

Newman, R. M., Lamers, S. L., Weiner, B., Ray, S. C., Colgrove, R. C., Diaz, F., Jing, L., Wang, K., Saif, S., Young, S., Henn, M., Laeyendecker, O. B., Tobian, A. A., Cohen, J. I., Koelle, D. M., Quinn, T. C. & Knipe, D. M., 2015, In : Journal of Virology. 89, 16, p. 8219-8232 14 p.

Research output: Contribution to journalArticle

Human herpesvirus 2
Human Herpesvirus 2
Genome
genome
Human Herpesvirus 1