Find Research Outputs

Search concepts
Selected Filters
2017
Behavioral Symptoms
Dementia
Therapeutics
Caregivers
Interviews

Characterizing Highly Benefited Patients in Randomized Clinical Trials

Charu, V., Rosenberg, P. B., Schneider, L. S., Drye, L. T., Rein, L., Shade, D., Lyketsos, C. G. & Frangakis, C. E. 2017 In : International Journal of Biostatistics. 13, 1, 20160045

Research output: Research - peer-reviewArticle

Randomized Clinical Trial
Clinical trials
Randomized Controlled Trials
Model
Predictors

Head injury serum markers for assessing response to trauma: Design of the HeadSMART study

Peters, M. E., Rao, V., Bechtold, K. T., Roy, D., Sair, H. I., Leoutsakos, J. M., Diaz-Arrastia, R., Stevens, R. D., Batty, D. S., Falk, H., Fernandez, C., Ofoche, U., Vassila, A., Hall, A. J., Anderson, B., Bessman, E., Lyketsos, C. G., Everett, A. D., Eyk, J. V. & Korley, F. K. Jan 30 2017 (Accepted/In press) In : Brain Injury. p. 1-9 9 p.

Research output: Research - peer-reviewArticle

Craniocerebral Trauma
Biomarkers
Wounds and Injuries
Traumatic Brain Injury
Head Injury

Imaging of glial cell activation and white matter integrity in brains of active and recently retired national football league players

Coughlin, J. M. , Yuchuanwang, Y. , Minn, I. , Bienko, N. , Ambinder, E. B. , Xu, X. , Peters, M. E. , Dougherty, J. W. , Vranesic, M. , Koo, S. M. , Ahn, H. H. , Lee, M. , Cottrell, C. , Sair, H. I. , Sawa, A. , Munro, C. A. , Nowinski, C. J. , Dannals, R. F. , Lyketsos, C. G. , Kassiou, M. & 5 others Smith, G., Caffo, B., Mori, S., Guilarte, T. R. & Pomper, M. G. Jan 1 2017 In : JAMA Neurology. 74, 1, p. 67-74 8 p.

Research output: Research - peer-reviewArticle

Football
Neuroglia
Brain
White Matter
Proteins

Neuropsychiatric signs and symptoms of Alzheimer's disease: New treatment paradigms

Lanctôt, K. L., Amatniek, J., Ancoli-Israel, S., Arnold, S. E., Ballard, C., Cohen-Mansfield, J., Ismail, Z., Lyketsos, C., Miller, D. S., Musiek, E., Osorio, R. S., Rosenberg, P. B., Satlin, A., Steffens, D., Tariot, P., Bain, L. J., Carrillo, M. C., Hendrix, J. A., Jurgens, H. & Boot, B. Sep 1 2017 In : Alzheimer's and Dementia: Translational Research and Clinical Interventions. 3, 3, p. 440-449 10 p.

Research output: Research - peer-reviewReview article

Signs and Symptoms
Alzheimer Disease
Therapeutics
Apathy
Institutionalization
Baltimore
Sphingomyelins
Ceramides
Longitudinal Studies
Alzheimer Disease

The Mild Behavioral Impairment Checklist (MBI-C): A Rating Scale for Neuropsychiatric Symptoms in Pre-Dementia Populations

Ismail, Z., Agüera-Ortiz, L., Brodaty, H., Cieslak, A., Cummings, J., Fischer, C. E., Gauthier, S., Geda, Y. E., Herrmann, N., Kanji, J., Lanctôt, K. L., Miller, D. S., Mortby, M. E., Onyike, C. U., Rosenberg, P. B., Smith, E. E., Smith, G. S., Sultzer, D. L. & Lyketsos, C. 2017 In : Journal of Alzheimer's Disease. 56, 3, p. 929-938 10 p.

Research output: Research - peer-reviewArticle

Checklist
Dementia
Research
Population
Therapeutics
Depressive Disorder
Type 2 Diabetes Mellitus
Depression
Population
Type 2 Diabetes
2016

A Call to Restructure Psychiatry General and Subspecialty Training

Kirwin, P., Conroy, M., Lyketsos, C., Greenwald, B., Forester, B., Devries, C., Ahmed, I. I., Wiechers, I., Zdanys, K., Steffens, D. & Reynolds, C. F. Feb 1 2016 In : Academic Psychiatry. 40, 1, p. 145-148 4 p.

Research output: Research - peer-reviewArticle

psychiatry
trainee
certification
Psychiatry
geriatrics

Age at menopause and duration of reproductive period in association with dementia and cognitive function: A systematic review and meta-analysis

Georgakis, M. K., Kalogirou, E. I., Diamantaras, A. A., Daskalopoulou, S. S., Munro, C. A., Lyketsos, C. G., Skalkidou, A. & Petridou, E. T. Nov 1 2016 In : Psychoneuroendocrinology. 73, p. 224-243 20 p.

Research output: Research - peer-reviewArticle

Menopause
Cognition
Reproduction
Dementia
Meta-Analysis

Alzheimer's disease risk polymorphisms regulate gene expression in the ZCWPW1 and the CELF1 loci

Karch, C. M. , Ezerskiy, L. A. , Bertelsen, S. , Goate, A. M. , Albert, M. S. , Albin, R. L. , Apostolova, L. G. , Arnold, S. E. , Baldwin, C. T. , Barber, R. , Barmada, M. M. , Barnes, L. L. , Beach, T. G. , Beecham, G. W. , Beekly, D. , Bennett, D. A. , Bigio, E. H. , Bird, T. D. , Blacker, D. , Boeve, B. F. & 144 others Bowen, J. D., Boxer, A., Burke, J. R., Buxbaum, J. D., Cairns, N. J., Cantwell, L. B., Cao, C., Carlson, C. S., Carney, R. M., Carrasquillo, M. M., Carroll, S. L., Chui, H. C., Clark, D. G., Corneveaux, J., Crane, P. K., Cribbs, D. H., Crocco, E. A., Cruchaga, C., De Jager, P. L., DeCarli, C., DeKosky, S. T., Demirci, F. Y., Dick, M., Dickson, D. W., Duara, R., Ertekin-Taner, N., Evans, D., Faber, K. M., Fallon, K. B., Farlow, M. R., Ferris, S., Foroud, T. M., Frosch, M. P., Galasko, D. R., Ganguli, M., Gearing, M., Geschwind, D. H., Ghetti, B., Gilbert, J. R., Gilman, S., Glass, J. D., Graff-Radford, N. R., Green, R. C., Growdon, J. H., Hakonarson, H., Hamilton-Nelson, K. L., Hamilton, R. L., Hardy, J., Harrell, L. E., Head, E., Honig, L. S., Huentelman, M. J., Hulette, C. M., Hyman, B. T., Jarvik, G. P., Jicha, G. A., Jin, L. W., Kamboh, M. I., Karydas, A., Kauwe, J. S. K., Kaye, J. A., Kim, R., Koo, E. H., Kowall, N. W., Kramer, J. H., Kramer, P., Kukull, W. A., LaFerla, F. M., Lah, J. J., Larson, E. B., Leverenz, J. B., Levey, A. I., Li, G., Lin, C. F., Lieberman, A. P., Lopez, O. L., Lunetta, K. L., Lyketsos, C. G., Mack, W. J., Marson, D. C., Martin, E. R., Martiniuk, F., Mash, D. C., Masliah, E., McCormick, W. C., McCurry, S. M., McDavid, A. N., McKee, A. C., Mesulam, M., Miller, B. L., Miller, C. A., Miller, J. W., Montine, T. J., Morris, J. C., Murrell, J. R., Myers, A. J., Naj, A. C., Olichney, J. M., Pankratz, V. S., Parisi, J. E., Peskind, E., Petersen, R. C., Pierce, A., Poon, W. W., Potter, H., Quinn, J. F., Raj, A., Rajbhandary, R. A., Raskind, M., Reiman, E. M., Reisberg, B., Reitz, C., Ringman, J. M., Roberson, E. D., Rogaeva, E., Rosen, H. J., Rosenberg, R. N., Sano, M., Saykin, A. J., Schneider, J. A., Schneider, L. S., Seeley, W. W., Smith, A. G., Sonnen, J. A., Spina, S., Stern, R. A., Tanzi, R. E., Trojanowski, J. Q., Troncoso, J. C., Tsuang, D. W., Valladares, O., Van Deerlin, V. M., Van Eldik, L. J., Vardarajan, B. N., Vinters, H. V., Vonsattel, J. P., Weintraub, S., Welsh-Bohmer, K. A., Williamson, J., Woltjer, R. L., Wright, C. B., Younkin, S. G., Yu, C. E. & Yu, L. Feb 1 2016 In : PLoS One. 11, 2, e0148717

Research output: Research - peer-reviewArticle

Alzheimer disease
genetic polymorphism
gene expression
loci
genome-wide association study

A novel Alzheimer disease locus located near the gene encoding tau protein

Jun, G. , Ibrahim-Verbaas, C. A. , Vronskaya, M. , Lambert, J. C. , Chung, J. , Naj, A. C. , Kunkle, B. W. , Wang, L. S. , Bis, J. C. , Bellenguez, C. , Harold, D. , Lunetta, K. L. , Destefano, A. L. , Grenier-Boley, B. , Sims, R. , Beecham, G. W. , Smith, A. V. , Chouraki, V. , Hamilton-Nelson, K. L. , Ikram, M. A. & 342 others Fievet, N., Denning, N., Martin, E. R., Schmidt, H., Kamatani, Y., Dunstan, M. L., Valladares, O., Laza, A. R., Zelenika, D., Ramirez, A., Foroud, T. M., Choi, S. H., Boland, A., Becker, T., Kukull, W. A., Van Der Lee, S. J., Pasquier, F., Cruchaga, C., Beekly, D., Fitzpatrick, A. L., Hanon, O., Gill, M., Barber, R., Gudnason, V., Campion, D., Love, S., Bennett, D. A., Amin, N., Berr, C., Tsolaki, M., Buxbaum, J. D., Lopez, O. L., Deramecourt, V., Fox, N. C., Cantwell, L. B., Tárraga, L., Dufouil, C., Hardy, J., Crane, P. K., Eiriksdottir, G., Hannequin, D., Clarke, R., Evans, D., Mosley, T. H., Letenneur, L., Brayne, C., Maier, W., De Jager, P., Emilsson, V., Dartigues, J. F., Hampel, H., Kamboh, M. I., De Bruijn, R. F. A. G., Tzourio, C., Pastor, P., Larson, E. B., Rotter, J. I., O'Donovan, M. C., Montine, T. J., Nalls, M. A., Mead, S., Reiman, E. M., Jonsson, P. V., Holmes, C., St George-Hyslop, P. H., Boada, M., Passmore, P., Wendland, J. R., Schmidt, R., Morgan, K., Winslow, A. R., Powell, J. F., Carasquillo, M., Younkin, S. G., Jakobsdóttir, J., Kauwe, J. S. K., Wilhelmsen, K. C., Rujescu, D., Nöthen, M. M., Hofman, A., Jones, L., Haines, J. L., Psaty, B. M., Van Broeckhoven, C., Holmans, P., Launer, L. J., Mayeux, R., Lathrop, M., Goate, A. M., Escott-Price, V., Seshadri, S., Pericak-Vance, M. A., Amouyel, P., Williams, J., Van Duijn, C. M., Schellenberg, G. D., Farrer, L. A., Adams, P. M., Albert, M. S., Albin, R. L., Apostolova, L. G., Arnold, S. E., Asthana, S., Atwood, C. S., Baldwin, C. T., Barmada, M. M., Barnes, L. L., Beach, T. G., Becker, J. T., Bigio, E. H., Bird, T. D., Blacker, D., Boeve, B. F., Bowen, J. D., Boxer, A., Burke, J. R., Cairns, N. J., Cao, C., Carlson, C. S., Carlsson, C. M., Carney, R. M., Carrasquillo, M. M., Carroll, S. L., Chui, H. C., Clark, D. G., Corneveaux, J., Cribbs, D. H., Crocco, E. A., Cruchaga, C., De Jager, P. L., DeCarli, C., DeKosky, S. T., Yesim Demirci, F., Dick, M., Dickson, D. W., Doody, R. S., Duara, R., Ertekin-Taner, N., Faber, K. M., Fairchild, T. J., Fallon, K. B., Farlow, M. R., Ferris, S., Frosch, M. P., Galasko, D. R., Gearing, M., Geschwind, D. H., Ghetti, B., Gilbert, J. R., Glass, J. D., Graff-Radford, N. R., Green, R. C., Growdon, J. H., Hakonarson, H., Hamilton, R. L., Hardy, J., Harrell, L. E., Head, E., Honig, L. S., Huebinger, R. M., Huentelman, M. J., Hulette, C. M., Hyman, B. T., Jarvik, G. P., Jicha, G. A., Jin, L. W., Karydas, A., Kauwe, J. S. K., Kaye, J. A., Kim, R., Koo, E. H., Kowall, N. W., Kramer, J. H., LaFerla, F. M., Lah, J. J., Leverenz, J. B., Levey, A. I., Li, G., Lieberman, A. P., Lin, C. F., Lopez, O. L., Lyketsos, C. G., Mack, W. J., Marson, D. C., Martiniuk, F., Mash, D. C., Masliah, E., McCormick, W. C., McCurry, S. M., McDavid, A. N., McKee, A. C., Mesulam, M., Miller, B. L., Miller, C. A., Miller, J. W., Morris, J. C., Mukherjee, S., Murrell, J. R., Myers, A. J., O'Bryant, S., Olichney, J. M., Pankratz, V. S., Parisi, J. E., Partch, A., Paulson, H. L., Perry, W., Peskind, E., Petersen, R. C., Pierce, A., Poon, W. W., Potter, H., Quinn, J. F., Raj, A., Raskind, M., Reisberg, B., Reisch, J. S., Reitz, C., Ringman, J. M., Roberson, E. D., Rogaeva, E., Rosen, H. J., Rosenberg, R. N., Royall, D. R., Sager, M. A., Sano, M., Saykin, A. J., Schneider, J. A., Schneider, L. S., Seeley, W. W., Smith, A. G., Sonnen, J. A., Spina, S., Stern, R. A., Tanzi, R. E., Thornton-Wells, T. A., Trojanowski, J. Q., Troncoso, J. C., Tsuang, D. W., Van Deerlin, V. M., Van Eldik, L. J., Vardarajan, B. N., Vinters, H. V., Vonsattel, J. P., Weintraub, S., Welsh-Bohmer, K. A., Williamson, J., Wishnek, S., Woltjer, R. L., Wright, C. B., Wu, C. K., Yu, C. E., Yu, L., Thomas, C., Gerrish, A., Chapman, J., Stretton, A., Morgan, A., Oldham, H., Owen, M. J., Kehoe, P. G., Medway, C., Brown, K., Lord, J., Turton, J., Hooper, N. M., Vardy, E., Warren, J. D., Schott, J. M., Uphill, J., Hollingworth, P., Ryan, N., Rossor, M., Collinge, J., Ben-Shlomo, Y., Makrina, D., Gkatzima, O., Lupton, M., Koutroumani, M., Avramidou, D., Germanou, A., Jessen, F., Riedel-Heller, S., Dichgans, M., Heun, R., Kölsch, H., Schürmann, B., Herold, C., Lacour, A., Drichel, D., Hoffmann, P., Kornhuber, J., Gu, W., Feulner, T., Mayhaus, M., Pichler, S., Riemenschneider, M., van den Bussche, H., Lawlor, B., Lynch, A., Mann, D., Smith, A. D., Warden, D., Wilcock, G., Heuser, I., Wiltfang, J., Frölich, L., Hüll, M., Mayo, K., Livingston, G., Bass, N. J., Gurling, H., McQuillin, A., Gwilliam, R., Deloukas, P., Al-Chalabi, A., Shaw, C. E., Singleton, A. B., Guerreiro, R., Russo, G., Jöckel, K. H., Moebus, S., Klopp, N., Wichmann, H. E., Dickson, D. W., Graff-Radford, N. R., Ma, L., Bisceglio, G., Fisher, E., Warner, N., Pickering-Brown, S., Craig, D., Johnston, J. A., McGuinness, B., Todd, S., Rubinsztein, D. C., Lovestone, S., Bayer, A., Gallacher, J., Proitsi, P., Ortega-Cubero, S., IGAP Consortium & Genetic and Environmental Risk in Alzheimer's Disease (GERAD) Consortium Jan 1 2016 In : Molecular Psychiatry. 21, 1, p. 108-117 10 p.

Research output: Research - peer-reviewArticle

tau Proteins
Single Nucleotide Polymorphism
Alzheimer Disease
Genes
Exons

A Phase II Study of Fornix Deep Brain Stimulation in Mild Alzheimer's Disease

Lozano, A. M. , Fosdick, L. , Chakravarty, M. M. , Leoutsakos, J. M. , Munro, C. , Oh, E. , Drake, K. E. , Lyman, C. H. , Rosenberg, P. B. , Anderson, W. S. , Tang-Wai, D. F. , Pendergrass, J. C. , Salloway, S. , Asaad, W. F. , Ponce, F. A. , Burke, A. , Sabbagh, M. , Wolk, D. A. , Baltuch, G. , Okun, M. S. & 6 others Foote, K. D., McAndrews, M. P., Giacobbe, P., Targum, S. D., Lyketsos, C. G. & Smith, G. S. Sep 6 2016 In : Journal of Alzheimer's Disease. 54, 2, p. 777-787 11 p.

Research output: Research - peer-reviewArticle

Brain Fornix
Deep Brain Stimulation
Alzheimer Disease
Glucose
Brain

A population pharmacokinetic model for R- and S-citalopram and desmethylcitalopram in Alzheimer’s disease patients with agitation

Akil, A., Bies, R. R., Pollock, B. G., Avramopoulos, D., Devanand, D. P., Mintzer, J. E., Porsteinsson, A. P., Schneider, L. S., Weintraub, D., Yesavage, J., Shade, D. M. & Lyketsos, C. G. Feb 1 2016 In : Journal of Pharmacokinetics and Pharmacodynamics. 43, 1, p. 99-109 11 p.

Research output: Research - peer-reviewArticle

Citalopram
Alzheimer Disease
Pharmacokinetics
Population
desmethylcitalopram

Assessment of the genetic variance of late-onset Alzheimer's disease

Adams, P. M. , Albert, M. S. , Albin, R. L. , Apostolova, L. G. , Arnold, S. E. , Asthana, S. , Atwood, C. S. , Baldwin, C. T. , Barber, R. C. , Barmada, M. M. , Barnes, L. L. , Barral, S. , Beach, T. G. , Becker, J. T. , Beecham, G. W. , Beekly, D. , Bennett, D. A. , Bigio, E. H. , Bird, T. D. , Blacker, D. & 174 others Boeve, B. F., Bowen, J. D., Boxer, A., Burke, J. R., Burns, J. M., Buxbaum, J. D., Cairns, N. J., Cantwell, L. B., Cao, C., Carlson, C. S., Carlsson, C. M., Carney, R. M., Carrasquillo, M. M., Carroll, S. L., Chui, H. C., Clark, D. G., Corneveaux, J., David, C. H., Crocco, E. A., Cruchaga, C., De Jager, P. L., DeCarli, C., Yesim Demirci, F., Dick, M., Dickson, D. W., Doody, R. S., Duara, R., Ertekin-Taner, N., Evans, D. A., Faber, K. M., Fairchild, T. J., Fallon, K. B., Fardo, D. W., Farlow, M. R., Ferris, S., Foroud, T. M., Frosch, M. P., Galasko, D. R., Gearing, M., Geschwind, D. H., Ghetti, B., Gilbert, J. R., Goate, A. M., Graff-Radford, N. R., Green, R. C., Growdon, J. H., Hakonarson, H., Hamilton, R. L., Hamilton-Nelson, K. L., Hardy, J., Harrell, L. E., Honig, L. S., Huebinger, R. M., Huentelman, M. J., Hulette, C. M., Hyman, B. T., Jarvik, G. P., Jicha, G. A., Jin, L. W., Jun, G., Kamboh, I. M., Karydas, A., Katz, M. J., Kaye, J. A., Kim, R., Kowall, N. W., Kramer, J. H., Kukull, W. A., Kunkle, B. W., LaFerla, F. M., Lah, J. J., Larson, E. B., Leverenz, J. B., Levey, A. I., Li, G., Lieberman, A. P., Lin, C. F., Lipton, R. B., Lopez, O. L., Lunetta, K. L., Lyketsos, C. G., Mack, W. J., Marson, D. C., Martin, E. R., Martiniuk, F., Mash, D. C., Masliah, E., McCormick, W. C., McCurry, S. M., McDavid, A. N., McKee, A. C., Mesulam, M., Miller, B. L., Miller, C. A., Miller, J. W., Montine, T. J., Morris, J. C., Mukherjee, S., Murrell, J. R., Myers, A. J., Naj, A. C., O'Bryant, S., Olichney, J. M., Pankratz, V. S., Parisi, J. E., Partch, A., Paulson, H. L., Perry, W., Peskind, E., Petersen, R. C., Pierce, A., Poon, W. W., Potter, H., Quinn, J. F., Raj, A., Raskind, M., Reiman, E. M., Reisberg, B., Reisch, J. S., Reitz, C., Ringman, J. M., Roberson, E. D., Rogaeva, E., Rosen, H. J., Rosenberg, R. N., Royall, D. R., Sager, M. A., Sano, M., Saykin, A. J., Schneider, J. A., Schneider, L. S., Seeley, W. W., Smith, A. G., Sonnen, J. A., Spina, S., St George-Hyslop, P., Stern, R. A., Swerdlow, R. H., Tanzi, R. E., Thornton-Wells, T. A., Trojanowski, J. Q., Troncoso, J. C., Tsuang, D. W., Valladares, O., Van Deerlin, V. M., Van Eldik, L. J., Vardarajan, B. N., Vinters, H. V., Vonsattel, J. P., Wang, L. S., Weintraub, S., Welsh-Bohmer, K. A., Wendland, J. R., Wilhelmsen, K. C., Williamson, J., Wingo, T. S., Winslow, A. R., Wishnek, S., Woltjer, R. L., Wright, C. B., Wu, C. K., Younkin, S. G., Yu, C. E., Yu, L., Ridge, P. G., Hoyt, K. B., Boehme, K., Crane, P. K., Haines, J. L., Mayeux, R., Farrer, L. A., Pericak-Vance, M. A., Schellenberg, G. D. & Kauwe, J. S. K. May 1 2016 In : Neurobiology of Aging. 41, p. 200.e13-200.e20

Research output: Research - peer-reviewArticle

Alzheimer Disease
Single Nucleotide Polymorphism
Inborn Genetic Diseases
Amyloid beta-Protein Precursor
Myeloid Cells

Bilateral deep brain stimulation of the fornix for Alzheimer's disease: Surgical safety in the ADvance trial

Ponce, F. A., Asaad, W. F., Foote, K. D., Anderson, W. S., Cosgrove, G. R., Baltuch, G. H., Beasley, K., Reymers, D. E., Oh, E. S., Targum, S. D., Smith, G. S., Lyketsos, C. G. & Lozano, A. M. Jul 1 2016 In : Journal of Neurosurgery. 125, 1, p. 75-84 10 p.

Research output: Research - peer-reviewArticle

Brain Fornix
Deep Brain Stimulation
Alzheimer Disease
Safety
Hospitalization

Case Study: Johns Hopkins Community Health Partnership: A model for transformation

Berkowitz, S. A., Brown, P., Brotman, D. J., Deutschendorf, A., Dunbar, L., Everett, A., Hickman, D., Howell, E., Purnell, L., Sylvester, C., Zollinger, R., Bellantoni, M., Durso, S. C., Lyketsos, C. & Rothman, P. Feb 8 2016 (Accepted/In press) In : Healthcare.

Research output: Research - peer-reviewArticle

Health
Skilled Nursing Facilities
Patient Care Bundles
Urban Health
Cost of Illness

Citalopram for the Treatment of Agitation in Alzheimer Dementia

Peters, M. E., Vaidya, V., Drye, L. T., Devanand, D. P., Mintzer, J. E., Pollock, B. G., Porsteinsson, A. P., Rosenberg, P. B., Schneider, L. S., Shade, D. M., Weintraub, D., Yesavage, J., Lyketsos, C. G. & Avramopoulos, D. Mar 1 2016 In : Journal of Geriatric Psychiatry and Neurology. 29, 2, p. 59-64 6 p.

Research output: Research - peer-reviewArticle

Citalopram
Alzheimer Disease
Therapeutics
Equipment and Supplies
Clinical Studies
Alzheimer Disease
Depression
Amyloid Plaques
Cognitive Dysfunction
Geriatrics

Closer caregiver and care-recipient relationships predict lower informal costs of dementia care: The Cache County Dementia Progression Study

Rattinger, G. B., Fauth, E. B., Behrens, S., Sanders, C., Schwartz, S., Norton, M. C., Corcoran, C., Mullins, C. D., Lyketsos, C. G. & Tschanz, J. A. T. 2016 (Accepted/In press) In : Alzheimer's and Dementia.

Research output: Research - peer-reviewArticle

Caregivers
Dementia
Costs and Cost Analysis
Patient Care
Salaries and Fringe Benefits

Editorial: Alzheimer's disease and the fornix

Oishi, K. & Lyketsos, C. G. Jun 23 2016 In : Frontiers in Aging Neuroscience. 8, JUN, 149

Research output: Research - peer-reviewEditorial

Effects of citalopram on neuropsychiatric symptoms in Alzheimer's dementia: Evidence from the CitAD study

Leonpacher, A. K., Peters, M. E., Drye, L. T., Makino, K. M., Newell, J. A., Devanand, D. P., Frangakis, C., Munro, C. A., Mintzer, J. E., Pollock, B. G., Rosenberg, P. B., Schneider, L. S., Shade, D. M., Weintraub, D., Yesavage, J., Lyketsos, C. G. & Porsteinsson, A. P. May 1 2016 In : American Journal of Psychiatry. 173, 5, p. 473-480 8 p.

Research output: Research - peer-reviewArticle

Citalopram
Alzheimer Disease
Odds Ratio
Delusions
Hallucinations
Health Services
Dementia
Inpatients
Ambulatory Care
Social Welfare

Heterogeneity of treatment response to citalopram for patients with Alzheimer's disease with aggression or agitation: The citad randomized clinical trial

Schneider, L. S., Frangakis, C., Drye, L. T., Devanand, D. P., Marano, C. M., Mintzer, J., Mulsant, B. H., Munro, C. A., Newell, J. A., Pawluczyk, S., Pelton, G., Pollock, B. G., Porsteinsson, A. P., Rabins, P. V., Rein, L., Rosenberg, P. B., Shade, D., Weintraub, D., Yesavage, J. & Lyketsos, C. G. May 1 2016 In : American Journal of Psychiatry. 173, 5, p. 465-472 8 p.

Research output: Research - peer-reviewArticle

Citalopram
Aggression
Alzheimer Disease
Randomized Controlled Trials
Therapeutics

Neuropsychiatric symptoms as early manifestations of emergent dementia: Provisional diagnostic criteria for mild behavioral impairment

Ismail, Z., Smith, E. E., Geda, Y., Sultzer, D., Brodaty, H., Smith, G., Agüera-Ortiz, L., Sweet, R., Miller, D. & Lyketsos, C. G. Feb 1 2016 In : Alzheimer's and Dementia. 12, 2, p. 195-202 8 p.

Research output: Research - peer-reviewArticle

Dementia
Cognitive Dysfunction
Neurobehavioral Manifestations
Cognition
Therapeutics

Nutritional Status is Associated with Faster Cognitive Decline and Worse Functional Impairment in the Progression of Dementia: The Cache County Dementia Progression Study

Sanders, C., Behrens, S., Schwartz, S., Wengreen, H., Corcoran, C. D., Lyketsos, C. G. & Tschanz, J. T. Apr 26 2016 In : Journal of Alzheimer's Disease. 52, 1, p. 33-42 10 p.

Research output: Research - peer-reviewArticle

Nutrition Assessment
Nutritional Status
Dementia
Cognitive Dysfunction
Malnutrition

Principal components analysis of agitation outcomes in Alzheimer's disease

Yesavage, J. A., Taylor, J. L., Friedman, L., Rosenberg, P. B., Lazzeroni, L. C., Leoutsakos, J. M. S., Kinoshita, L. M., Perlow, M. J., Munro, C. A., Devanand, D. P., Drye, L. T., Mintzer, J. E., Pollock, B. G., Porsteinsson, A. P., Schneider, L. S., Shade, D. M., Weintraub, D., Lyketsos, C. G. & Noda, A. Aug 1 2016 In : Journal of Psychiatric Research. 79, p. 4-7 4 p.

Research output: Research - peer-reviewArticle

Citalopram
Principal Component Analysis
Alzheimer Disease
Alzheimer's Disease
Equipment and Supplies

R- and S-citalopram concentrations have differential effects on neuropsychiatric scores in elders with dementia and agitation

Ho, T., Pollock, B. G., Mulsant, B. H., Schantz, O., Devanand, D. P., Mintzer, J. E., Porsteinsson, A. P., Schneider, L. S., Weintraub, D., Yesavage, J., Drye, L. T., Munro, C. A., Shade, D. M., Lyketsos, C. & Bies, R. 2016 In : British Journal of Clinical Pharmacology. p. 784-792 9 p.

Research output: Research - peer-reviewArticle

Citalopram
Area Under Curve
Dementia
Therapeutics
Alzheimer Disease
Caregivers
Dementia
Randomized Controlled Trials
Costs and Cost Analysis
Control Groups

Sedation mediates part of Citalopram's effect on agitation in Alzheimer's disease

Newell, J., Yesavage, J. A., Taylor, J. L., Kraemer, H. C., Munro, C. A., Friedman, L., Rosenberg, P. B., Madore, M., Chao, S. Z., Devanand, D. P., Drye, L. T., Mintzer, J. E., Pollock, B. G., Porsteinsson, A. P., Schneider, L. S., Shade, D. M., Weintraub, D., Lyketsos, C. G. & Noda, A. Mar 1 2016 In : Journal of Psychiatric Research. 74, p. 17-21 5 p.

Research output: Research - peer-reviewArticle

Citalopram
Alzheimer Disease
Alzheimer's Disease
Placebos
Placebo
Self Care
Type 2 Diabetes Mellitus
Depression
Health
Population

WeCareAdvisor™: The Development of a Caregiver-focused, Web-based Program to Assess and Manage Behavioral and Psychological Symptoms of Dementia

Kales, H. C., Gitlin, L. N., Stanislawski, B., Marx, K., Turnwald, M., Watkins, D. C. & Lyketsos, C. G. Nov 15 2016 (Accepted/In press) In : Alzheimer Disease and Associated Disorders.

Research output: Research - peer-reviewArticle

Behavioral Symptoms
Caregivers
Dementia
Psychology
Licensure
2015

Agitation in cognitive disorders: International Psychogeriatric Association provisional consensus clinical and research definition

Cummings, J., Mintzer, J., Brodaty, H., Sano, M., Banerjee, S., Devanand, D. P., Gauthier, S., Howard, R., Lanctôt, K., Lyketsos, C. G., Peskind, E., Porsteinsson, A. P., Reich, E., Sampaio, C., Steffens, D., Wortmann, M. & Zhong, K. Jan 12 2015 In : International Psychogeriatrics. 27, 1, p. 7-17 11 p.

Research output: Research - peer-reviewArticle

Consensus
Research
Surveys and Questionnaires
Aggression
Cognitive Dysfunction
Organizations
Referral and Consultation
Research
Community-Institutional Relations
Independent Living
Caregivers
Dementia
Randomized Controlled Trials
Quality of Life
Depression

Assessment and management of behavioral and psychological symptoms of dementia

Kales, H. C., Gitlin, L. N. & Lyketsos, C. G. Mar 2 2015 In : BMJ (Online). 350, h369

Research output: Research - peer-reviewArticle

Behavioral Symptoms
Caregivers
Dementia
Psychology
Therapeutics

Association of long runs of homozygosity with Alzheimer disease among African American individuals

Ghani, M. , Reitz, C. , Cheng, R. , Vardarajan, B. N. , Jun, G. , Sato, C. , Naj, A. , Rajbhandary, R. , Wang, L. S. , Valladares, O. , Lin, C. F. , Larson, E. B. , Graff-Radford, N. R. , Evans, D. , De Jager, P. L. , Crane, P. K. , Buxbaum, J. D. , Murrell, J. R. , Raj, T. , Ertekin-Taner, N. & 153 others Logue, M., Baldwin, C. T., Green, R. C., Barnes, L. L., Cantwell, L. B., Fallin, M. D., Go, R. C. P., Griffith, P. A., Obisesan, T. O., Manly, J. J., Lunetta, K. L., Kamboh, M. I., Lopez, O. L., Bennett, D. A., Hendrie, H., Hall, K. S., Goate, A. M., Byrd, G. S., Kukull, W. A., Foroud, T. M., Haines, J. L., Farrer, L. A., Pericak-Vance, M. A., Lee, J. H., Schellenberg, G. D., St. George-Hyslop, P., Mayeux, R., Rogaeva, E., Albert, M. S., Albin, R. L., Apostolova, L. G., Arnold, S. E., Barber, R., Barmada, M. M., Beach, T. G., Beecham, G. W., Beekly, D., Bigio, E. H., Bird, T. D., Blacker, D., Boeve, B. F., Bowen, J. D., Boxer, A., Burke, J. R., Cai, G., Cairns, N. J., Cao, C., Carlson, C. S., Carney, R. M., Carroll, S. L., Chui, H. C., Clark, D. G., Cribbs, D. H., Crocco, E. A., Cruchaga, C., DeCarli, C., DeKosky, S. T., Demirci, F. Y., Dick, M., Faber, K. M., Fallon, K. B., Ferris, S., Frosch, M. P., Galasko, D. R., Ganguli, M., Gearing, M., Geschwind, D. H., Ghetti, B., Gilbert, J. R., Gilman, S., Glass, J. D., Growdon, J. H., Hakonarson, H., Hamilton, R. L., Hamilton-Nelson, K. L., Haroutunian, V., Harrell, L. E., Honig, L. S., Hulette, C. M., Hyman, B. T., Jarvik, G. P., Jicha, G. A., Jin, L. W., Karydas, A., Kauwe, J. S. K., Kaye, J. A., Kim, R., Koo, E. H., Kowall, N. W., Kramer, J. H., Kramer, P., LaFerla, F. M., Lah, J. J., Lang-Walker, R., Leverenz, J. B., Levey, A. I., Li, G., Lieberman, A. P., Lyketsos, C. G., Mack, W. J., Marson, D. C., Martiniuk, F., Mash, D. C., Masliah, E., McCormick, W. C., McCurry, S. M., McDavid, A. N., McKee, A. C., Mesulam, M., Miller, B. L., Miller, C. A., Miller, J. W., Montine, T. J., Morris, J. C., Olichney, J. M., Parisi, J. E., Peskind, E., Petersen, R. C., Pierce, A., Poon, W. W., Potter, H., Quinn, J. F., Raj, A., Raskind, M., Reiman, E. M., Reisberg, B., Ringman, J. M., Roberson, E. D., Sano, M., Saykin, A. J., Schneider, J. A., Schneider, L. S., Seeley, W. W., Smith, A. G., Sonnen, J. A., Spina, S., Stern, R. A., Tanzi, R. E., Trojanowski, J. Q., Troncoso, J. C., Tsuang, D. W., Van Deerlin, V. M., Van Eldik, L. J., Vinters, H. V., Vonsattel, J. P., Weintraub, S., Welsh-Bohmer, K. A., Williamson, J., Woltjer, R. L., Wright, C. B., Younkin, S. G., Yu, C. E. & Yu, L. Nov 1 2015 In : JAMA Neurology. 72, 11, p. 1313-1323 11 p.

Research output: Research - peer-reviewArticle

African Americans
Alzheimer Disease
Datasets
Single Nucleotide Polymorphism
Consensus

Associations between Potentially Modifiable Risk Factors and Alzheimer Disease: A Mendelian Randomization Study

Østergaard, S. D. , Mukherjee, S. , Sharp, S. J. , Proitsi, P. , Lotta, L. A. , Day, F. , Perry, J. R. B. , Boehme, K. L. , Walter, S. , Kauwe, J. S. , Gibbons, L. E. , Larson, E. B. , Powell, J. F. , Langenberg, C. , Crane, P. K. , Wareham, N. J. , Scott, R. A. , Albert, M. S. , Albin, R. L. , Apostolova, L. G. & 296 others Arnold, S. E., Asthana, S., Atwood, C. S., Baldwin, C. T., Barber, R. C., Barmada, M. M., Barnes, L. L., Beach, T. G., Becker, J. T., Beecham, G. W., Beekly, D., Bigio, E. H., Bird, T. D., Blacker, D., Boeve, B. F., Bowen, J. D., Boxer, A., Burke, J. R., Buxbaum, J. D., Cairns, N. J., Cantwell, L. B., Cao, C., Carlson, C. S., Carlsson, C. M., Carney, R. M., Carrasquillo, M. M., Carroll, S. L., Chui, H. C., Clark, D. G., Corneveaux, J., Cribbs, D. H., Crocco, E. A., Cruchaga, C., De Jager, P. L., DeCarli, C., Demirci, F. Y., Dick, M., Dickson, D. W., Duara, R., Ertekin-Taner, N., Evans, D., Faber, K. M., Fallon, K. B., Farlow, M. R., Farrer, L. A., Ferris, S., Foroud, T. M., Frosch, M. P., Galasko, D. R., Gearing, M., Geschwind, D. H., Ghetti, B., Gilbert, J. R., Glass, J. D., Goate, A. M., Graff-Radford, N. R., Green, R. C., Growdon, J. H., Haines, J. L., Hakonarson, H., Hamilton, R. L., Hamilton-Nelson, K. L., Hardy, J., Harrell, L. E., Head, E., Honig, L. S., Huebinger, R. M., Huentelman, M. J., Hulette, C. M., Hyman, B. T., Jarvik, G. P., Jicha, G. A., Jin, L. W., Jun, G., Kamboh, M. I., Karydas, A., Kaye, J. A., Kim, R., Kowall, N. W., Kramer, J. H., Kukull, W. A., Kunkle, B. W., LaFerla, F. M., Lah, J. J., Leverenz, J. B., Levey, A. I., Li, G., Lieberman, A. P., Lin, C. F., Lopez, O. L., Lunetta, K. L., Lyketsos, C. G., Mack, W. J., Marson, D. C., Martin, E. R., Martiniuk, F., Mash, D. C., Masliah, E., Mayeux, R., McCormick, W. C., McCurry, S. M., McDavid, A. N., McKee, A. C., Mesulam, M., Miller, B. L., Miller, C. A., Miller, J. W., Montine, T. J., Morris, J. C., Murrell, J. R., Myers, A. J., Naj, A. C., Olichney, J. M., Pankratz, V. S., Parisi, J. E., Partch, A., Paulson, H. L., Pericak-Vance, M. A., Perry, W., Peskind, E., Petersen, R. C., Pierce, A., Poon, W. W., Potter, H., Quinn, J. F., Raj, A., Raskind, M., Reiman, E. M., Reisberg, B., Reitz, C., Ringman, J. M., Roberson, E. D., Rogaeva, E., Rosen, H. J., Rosenberg, R. N., Sager, M. A., Sano, M., Schellenberg, G. D., Schneider, J. A., Schneider, L. S., Seeley, W. W., Smith, A. G., Sonnen, J. A., Spina, S., St George-Hyslop, P., Stern, R. A., Tanzi, R. E., Thornton-Wells, T. A., Trojanowski, J. Q., Troncoso, J. C., Tsuang, D. W., Valladares, O., VanDeerlin, V. M., Van Eldik, L. J., Vardarajan, B. N., Vinters, H. V., Vonsattel, J. P., Wang, L. S., Weintraub, S., Welsh-Bohmer, K. A., Williamson, J., Wishnek, S., Woltjer, R. L., Wright, C. B., Younkin, S. G., Yu, C. E., Yu, L., Harold, D., Abraham, R., Hollingworth, P., Sims, R., Gerrish, A., Chapman, J., Russo, G., Hamshere, M., Singh Pahwa, J., Escott-Price, V., Badarinarayan, N., Dowzell, K., Williams, A., Jones, N., Thomas, C., Stretton, A., Morgan, A., Taylor, S., Lovestone, S., Powell, J., Proitsi, P., Lupton, M. K., Brayne, C., Rubinsztein, D. C., Gill, M., Lawlor, B., Lynch, A., Morgan, K., Brown, K., Passmore, P., Craig, D., McGuinness, B., Todd, S., Johnston, J., Holmes, C., Mann, D., David Smith, A., Love, S., Kehoe, P. G., Hardy, J., Mead, S., Fox, N., Rossor, M., Collinge, J., Maier, W., Jessen, F., Heun, R., Schürmann, B., Ramirez, A., Becker, T., Herold, C., Lacour, A., Drichel, D., van den Bussche, H., Heuser, I., Kornhuber, J., Wiltfang, J., Dichgans, M., Frölich, L., Hampel, H., Hüll, M., Rujescu, D., Goate, A., Kauwe, J. S. K., Cruchaga, C., Nowotny, P., Morris, J. C., Mayo, K., Livingston, G., Bass, N. J., Gurling, H., McQuillin, A., Gwilliam, R., Deloukas, P., Al-Chalabi, A., Shaw, C. E., Singleton, A. B., Guerreiro, R., Mühleisen, T. W., Nöthen, M. M., Moebus, S., Jöckel, K. H., Klopp, N., Wichmann, H. E., Carrasquillo, M. M., Shane Pankratz, V., Younkin, S. G., Holmans, P., Donovan, M. O., Owen, M. J., Williams, J., Langenberg, C., Scott, R. A., Sharp, S. J., Forouhi, N. G., Kerrison, N. D., Sims, M., Lucarelli, D. M. E., Barroso, I., Deloukas, P., McCarthy, M. I., Arriola, L., Balkau, B., Barricarte, A., Boeing, H., Franks, P. W., Gonzalez, C., Grioni, S., Kaaks, R., Key, T. J., Navarro, C., Nilsson, P. M., Overvad, K., Palli, D., Panico, S., Ramón Quirós, J., Rolandsson, O., Sacerdote, C., Sánchez, M. J., Slimani, N., Tjonneland, A., Tumino, R., van der Daphne, A. L., van der Schouw, Y. T., Riboli, E., Wareham, N. J., Alzheimer’s Disease Genetics Consortium, The GERAD1 Consortium & EPIC-InterAct Consortium Jun 1 2015 In : PLoS Medicine. 12, 6, e1001841

Research output: Research - peer-reviewArticle

Random Allocation
Single Nucleotide Polymorphism
Alzheimer Disease
Smoking
Odds Ratio

Atlas-based diffusion tensor imaging correlates of executive function

Nowrangi, M. A., Okonkwo, O., Lyketsos, C., Oishi, K., Mori, S., Albert, M. & Mielke, M. M. 2015 In : Journal of Alzheimer's Disease. 44, 2, p. 585-598 14 p.

Research output: Research - peer-reviewArticle

Diffusion Tensor Imaging
Atlases
Executive Function
Anisotropy
Cognitive Dysfunction

Beyond memory: A focus on the other neuropsychiatric symptoms of dementia

Peters, M. E. & Lyketsos, C. G. Feb 1 2015 In : American Journal of Geriatric Psychiatry. 23, 2, p. 115-118 4 p.

Research output: Research - peer-reviewArticle

Caregiver report versus clinician impression: Disagreements in rating neuropsychiatric symptoms in Alzheimer's disease patients

Stella, F., Forlenza, O. V., Laks, J., De Andrade, L. P., De Castilho Cação, J., Govone, J. S., De Medeiros, K. & Lyketsos, C. G. Dec 1 2015 In : International Journal of Geriatric Psychiatry. 30, 12, p. 1230-1237 8 p.

Research output: Research - peer-reviewArticle

Caregivers
Alzheimer Disease
Dementia
Depression
Apathy

Change in agitation in Alzheimer's disease in the placebo arm of a nine-week controlled trial

Rosenberg, P. B., Drye, L. T., Porsteinsson, A. P., Pollock, B. G., Devanand, D. P., Frangakis, C., Ismail, Z., Marano, C., Meinert, C. L., Mintzer, J. E., Munro, C. A., Pelton, G., Rabins, P. V., Schneider, L. S., Shade, D. M., Weintraub, D., Newell, J., Yesavage, J. & Lyketsos, C. G. Dec 1 2015 In : International Psychogeriatrics. 27, 12, p. 2059-2067 9 p.

Research output: Research - peer-reviewArticle

Alzheimer Disease
Placebos
Equipment and Supplies
Citalopram
Activities of Daily Living

Deep brain stimulation targeting the fornix for mild Alzheimer dementia: Design of the ADvance randomized controlled trial

Holroyd, K. B. , Fosdick, L. , Smith, G. S. , Leoutsakos, J. M. , Munro, C. A. , Oh, E. S. , Drake, K. E. , Rosenberg, P. B. , Anderson, W. S. , Salloway, S. , Pendergrass, J. C. , Burke, A. D. , Wolk, D. A. , Tang-Wai, D. F. , Ponce, F. A. , Asaad, W. F. , Sabbagh, M. N. , Okun, M. S. , Baltuch, G. , Foote, K. D. & 3 others Targum, S. D., Lozano, A. M. & Lyketsos, C. G. Jul 10 2015 In : Open Access Journal of Clinical Trials. 7, p. 63-76 14 p.

Research output: Research - peer-reviewArticle

Deep Brain Stimulation
Alzheimer Disease
Randomized Controlled Trials
Dementia
Placebos

Delirium

Heffernan, S. P., Oh, E., Lyketsos, C. & Neufeld, K. Jan 20 2015 Troublesome Disguises: Managing Challenging Disorders in Psychiatry: Second Edition. Wiley Blackwell, p. 186-198 13 p.

Research output: ResearchChapter

Delirium
Psychiatry
Diagnostic Errors
Consciousness
Cognition

Dementia caregivers coping strategies and their relationship to health and well-being: The Cache County Study

Snyder, C. M., Fauth, E., Wanzek, J., Piercy, K. W., Norton, M. C., Corcoran, C., Rabins, P. V., Lyketsos, C. G. & Tschanz, J. T. Jan 1 2015 In : Aging and Mental Health. 19, 5, p. 390-399 10 p.

Research output: Research - peer-reviewArticle

Caregivers
Dementia
Health
Anxiety
Equipment and Supplies

Dementia in patients with schizophrenia: Evidence for heterogeneity

Lyketsos, C. G. & Peters, M. E. Nov 1 2015 In : JAMA Psychiatry. 72, 11, p. 1075-1076 2 p.

Research output: Research - peer-reviewArticle

Dementia severity and the longitudinal costs of informal care in the Cache County population

Rattinger, G. B., Schwartz, S., Mullins, C. D., Corcoran, C., Zuckerman, I. H., Sanders, C., Norton, M. C., Fauth, E. B., Leoutsakos, J. M. S., Lyketsos, C. G. & Tschanz, J. T. Aug 1 2015 In : Alzheimer's and Dementia. 11, 8, p. 946-954 9 p., 1943

Research output: Research - peer-reviewArticle

Dementia
Patient Care
Costs and Cost Analysis
Population
Salaries and Fringe Benefits

Depression and incident alzheimer disease: The impact of disease severity

Gracia-García, P., De-La-Cámara, C., Santabárbara, J., Lopez-Anton, R., Quintanilla, M. A., Ventura, T., Marcos, G., Campayo, A., Saz, P., Lyketsos, C. & Lobo, A. Feb 1 2015 In : American Journal of Geriatric Psychiatry. 23, 2, p. 119-129 11 p.

Research output: Research - peer-reviewArticle

Alzheimer Disease
Depression
Geriatrics
Incidence
Proportional Hazards Models

Effect of dextromethorphan-quinidine on agitation in patients with Alzheimer disease dementia a randomized clinical trial

Cummings, J. L., Lyketsos, C. G., Peskind, E. R., Porsteinsson, A. P., Mintzer, J. E., Scharre, D. W., De La Gandara, J. E., Agronin, M., Davis, C. S., Nguyen, U., Shin, P., Tariot, P. N. & Siffert, J. Sep 22 2015 In : Journal of the American Medical Association. 314, 12, p. 1242-1254 13 p.

Research output: Research - peer-reviewArticle

Dextromethorphan
Quinidine
Alzheimer Disease
Randomized Controlled Trials
Placebos