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2017

A randomized trial of a web-based platform to help families manage dementia-related behavioral symptoms: The WeCareAdvisor™

Gitlin, L. N., Kales, H. C., Marx, K., Stanislawski, B. & Lyketsos, C., Nov 1 2017, In : Contemporary Clinical Trials. 62, p. 27-36 10 p.

Research output: Contribution to journalArticle

Behavioral Symptoms
Dementia
Caregivers
Interviews
Therapeutics

Characterizing Highly Benefited Patients in Randomized Clinical Trials

Charu, V., Rosenberg, P. B., Schneider, L. S., Drye, L. T., Rein, L., Shade, D., Lyketsos, C. G. & Frangakis, C. E., 2017, In : International Journal of Biostatistics. 13, 1, 20160045

Research output: Contribution to journalArticle

Randomized Clinical Trial
Randomized Controlled Trials
Randomized Controlled Trial
Predictors
Covariates

Head injury serum markers for assessing response to trauma: Design of the HeadSMART study

Peters, M. E., Rao, V., Bechtold, K. T., Roy, D., Sair, H. I., Leoutsakos, J. M., Diaz-Arrastia, R., Stevens, R. D., Batty, D. S., Falk, H., Fernandez, C., Ofoche, U., Vassila, A., Hall, A. J., Anderson, B., Bessman, E., Lyketsos, C. G., Everett, A. D., Eyk, J. V. & Korley, F. K., Jan 30 2017, (Accepted/In press) In : Brain Injury. p. 1-9 9 p.

Research output: Contribution to journalArticle

Craniocerebral Trauma
Biomarkers
Wounds and Injuries
Hospital Emergency Service
Arm

Imaging of glial cell activation and white matter integrity in brains of active and recently retired national football league players

Coughlin, J. M. , Yuchuanwang, Y. , Minn, I. , Bienko, N. , Ambinder, E. B. , Xu, X. , Peters, M. E. , Dougherty, J. W. , Vranesic, M. , Koo, S. M. , Ahn, H. H. , Lee, M. , Cottrell, C. , Sair, H. I. , Sawa, A. , Munro, C. A. , Nowinski, C. J. , Dannals, R. F. , Lyketsos, C. G. , Kassiou, M. & 5 others Smith, G., Caffo, B., Mori, S., Guilarte, T. R. & Pomper, M. G., Jan 1 2017, In : JAMA Neurology. 74, 1, p. 67-74 8 p.

Research output: Contribution to journalArticle

Football
Neuroglia
Brain
Athletes
Sports

Neuropsychiatric aspects of dementia

Perera, N., Javeed, M., Lyketsos, C. G. & Leroi, I., Jan 1 2017, Dementia, Fifth Edition. CRC Press, p. 59-66 8 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Behavioral Symptoms
Homicide
Spouses
Dementia
Alzheimer Disease

Neuropsychiatric signs and symptoms of Alzheimer's disease: New treatment paradigms

Lanctôt, K. L., Amatniek, J., Ancoli-Israel, S., Arnold, S. E., Ballard, C., Cohen-Mansfield, J., Ismail, Z., Lyketsos, C., Miller, D. S., Musiek, E., Osorio, R. S., Rosenberg, P. B., Satlin, A., Steffens, D., Tariot, P., Bain, L. J., Carrillo, M. C., Hendrix, J. A., Jurgens, H. & Boot, B., Sep 1 2017, In : Alzheimer's and Dementia: Translational Research and Clinical Interventions. 3, 3, p. 440-449 10 p.

Research output: Contribution to journalReview article

Signs and Symptoms
Alzheimer Disease
Therapeutics
Apathy
Institutionalization

Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

Sims, R. , Van Der Lee, S. J. , Naj, A. C. , Bellenguez, C. , Badarinarayan, N. , Jakobsdottir, J. , Kunkle, B. W. , Boland, A. , Raybould, R. , Bis, J. C. , Martin, E. R. , Grenier-Boley, B. , Heilmann-Heimbach, S. , Chouraki, V. , Kuzma, A. B. , Sleegers, K. , Vronskaya, M. , Ruiz, A. , Graham, R. R. , Olaso, R. & 426 others Hoffmann, P., Grove, M. L., Vardarajan, B. N., Hiltunen, M., Nöthen, M. M., White, C. C., Hamilton-Nelson, K. L., Epelbaum, J., Maier, W., Choi, S. H., Beecham, G. W., Dulary, C., Herms, S., Smith, A. V., Funk, C. C., Derbois, C., Forstner, A. J., Ahmad, S., Li, H., Bacq, D., Harold, D., Satizabal, C. L., Valladares, O., Squassina, A., Thomas, R., Brody, J. A., Qu, L., Sánchez-Juan, P., Morgan, T., Wolters, F. J., Zhao, Y., Garcia, F. S., Denning, N., Fornage, M., Malamon, J., Naranjo, M. C. D., Majounie, E., Mosley, T. H., Dombroski, B., Wallon, D., Lupton, M. K., Dupuis, J., Whitehead, P., Fratiglioni, L., Medway, C., Jian, X., Mukherjee, S., Keller, L., Brown, K., Lin, H., Cantwell, L. B., Panza, F., McGuinness, B., Moreno-Grau, S., Burgess, J. D., Solfrizzi, V., Proitsi, P., Adams, H. H., Allen, M., Seripa, D., Pastor, P., Cupples, L. A., Price, N. D., Hannequin, D., Frank-García, A., Levy, D., Chakrabarty, P., Caffarra, P., Giegling, I., Beiser, A. S., Giedraitis, V., Hampel, H., Garcia, M. E., Wang, X., Lannfelt, L., Mecocci, P., Eiriksdottir, G., Crane, P. K., Pasquier, F., Boccardi, V., Henández, I., Barber, R. C., Scherer, M., Tarraga, L., Adams, P. M., Leber, M., Chen, Y., Albert, M. S., Riedel-Heller, S., Emilsson, V., Beekly, D., Braae, A., Schmidt, R., Blacker, D., Masullo, C., Schmidt, H., Doody, R. S., Spalletta, G., Longstreth, W. T., Fairchild, T. J., Bossù, P., Lopez, O. L., Frosch, M. P., Sacchinelli, E., Ghetti, B., Yang, Q., Huebinger, R. M., Jessen, F., Li, S., Kamboh, M. I., Morris, J. C., Sotolongo-Grau, O., Katz, M. J., Corcoran, C., Dunstan, M., Braddel, A., Thomas, C., Meggy, A., Marshall, R., Gerrish, A., Chapman, J., Aguilar, M., Taylor, S., Hill, M., Fairén, M. D., Hodges, A., Vellas, B., Soininen, H., Kloszewska, I., Daniilidou, M., Uphill, J., Patel, Y., Hughes, J. T., Lord, J., Turton, J., Hartmann, A. M., Cecchetti, R., Fenoglio, C., Serpente, M., Arcaro, M., Caltagirone, C., Orfei, M. D., Ciaramella, A., Pichler, S., Mayhaus, M., Gu, W., Lleó, A., Fortea, J., Blesa, R., Barber, I. S., Brookes, K., Cupidi, C., Maletta, R. G., Carrell, D., Sorbi, S., Moebus, S., Urbano, M., Pilotto, A., Kornhuber, J., Bosco, P., Todd, S., Craig, D., Johnston, J., Gill, M., Lawlor, B., Lynch, A., Fox, N. C., Hardy, J., Albin, R. L., Apostolova, L. G., Arnold, S. E., Asthana, S., Atwood, C. S., Baldwin, C. T., Barnes, L. L., Barral, S., Beach, T. G., Becker, J. T., Bigio, E. H., Bird, T. D., Boeve, B. F., Bowen, J. D., Boxer, A., Burke, J. R., Burns, J. M., Buxbaum, J. D., Cairns, N. J., Cao, C., Carlson, C. S., Carlsson, C. M., Carney, R. M., Carrasquillo, M. M., Carroll, S. L., Diaz, C. C., Chui, H. C., Clark, D. G., Cribbs, D. H., Crocco, E. A., Decarli, C., Dick, M., Duara, R., Evans, D. A., Faber, K. M., Fallon, K. B., Fardo, D. W., Farlow, M. R., Ferris, S., Foroud, T. M., Galasko, D. R., Gearing, M., Geschwind, D. H., Gilbert, J. R., Graff-Radford, N. R., Green, R. C., Growdon, J. H., Hamilton, R. L., Harrell, L. E., Honig, L. S., Huentelman, M. J., Hulette, C. M., Hyman, B. T., Jarvik, G. P., Abner, E., Jin, L. W., Jun, G., Karydas, A., Kaye, J. A., Kim, R., Kowall, N. W., Kramer, J. H., Laferla, F. M., Lah, J. J., Leverenz, J. B., Levey, A. I., Li, G., Lieberman, A. P., Lunetta, K. L., Lyketsos, C. G., Marson, D. C., Martiniuk, F., Mash, D. C., Masliah, E., McCormick, W. C., McCurry, S. M., McDavid, A. N., McKee, A. C., Mesulam, M., Miller, B. L., Miller, C. A., Miller, J. W., Murrell, J. R., Myers, A. J., O'Bryant, S., Olichney, J. M., Pankratz, V. S., Parisi, J. E., Paulson, H. L., Perry, W., Peskind, E., Pierce, A., Poon, W. W., Potter, H., Quinn, J. F., Raj, A., Raskind, M., Reisberg, B., Reitz, C., Ringman, J. M., Roberson, E. D., Rogaeva, E., Rosen, H. J., Rosenberg, R. N., Sager, M. A., Saykin, A. J., Schneider, J. A., Schneider, L. S., Seeley, W. W., Smith, A. G., Sonnen, J. A., Spina, S., Stern, R. A., Swerdlow, R. H., Tanzi, R. E., Thornton-Wells, T. A., Trojanowski, J. Q., Troncoso, J. C., Van Deerlin, V. M., Van Eldik, L. J., Vinters, H. V., Vonsattel, J. P., Weintraub, S., Welsh-Bohmer, K. A., Wilhelmsen, K. C., Williamson, J., Wingo, T. S., Woltjer, R. L., Wright, C. B., Yu, C. E., Yu, L., Garzia, F., Golamaully, F., Septier, G., Engelborghs, S., Vandenberghe, R., De Deyn, P. P., Fernadez, C. M., Benito, Y. A., Thonberg, H., Forsell, C., Lilius, L., Kinhult-Stählbom, A., Kilander, L., Brundin, R., Concari, L., Helisalmi, S., Koivisto, A. M., Haapasalo, A., Dermecourt, V., Fievet, N., Hanon, O., Dufouil, C., Brice, A., Ritchie, K., Dubois, B., Himali, J. J., Keene, C. D., Tschanz, J., Fitzpatrick, A. L., Kukull, W. A., Norton, M., Aspelund, T., Larson, E. B., Munger, R., Rotter, J. I., Lipton, R. B., Bullido, M. J., Hofman, A., Montine, T. J., Coto, E., Boerwinkle, E., Petersen, R. C., Alvarez, V., Rivadeneira, F., Reiman, E. M., Gallo, M., O'Donnell, C. J., Reisch, J. S., Bruni, A. C., Royall, D. R., Dichgans, M., Sano, M., Galimberti, D., St George-Hyslop, P., Scarpini, E., Tsuang, D. W., Mancuso, M., Bonuccelli, U., Winslow, A. R., Daniele, A., Wu, C. K., Peters, O., Nacmias, B., Riemenschneider, M., Heun, R., Brayne, C., Rubinsztein, D. C., Bras, J., Guerreiro, R., Al-Chalabi, A., Shaw, C. E., Collinge, J., Mann, D., Clarimón, J., Sussams, R., Lovestone, S., O'Donovan, M. C., Owen, M. J., Behrens, T. W., Mead, S., Uitterlinden, A. G., Uitterlinden, A. G., Cruchaga, C., Ingelsson, M., Bennett, D. A., Powell, J., Golde, T. E., Graff, C., De Jager, P. L., Morgan, K., Ertekin-Taner, N., Combarros, O., Psaty, B. M., Passmore, P., Younkin, S. G., Berr, C., Gudnason, V., Rujescu, D., Dickson, D. W., Dartigues, J. F., Destefano, A. L., Ortega-Cubero, S., Hakonarson, H., Campion, D., Boada, M., Kauwe, J. K., Farrer, L. A., Van Broeckhoven, C., Ikram, M. A., Jones, L., Haines, J. L., Tzourio, C., Launer, L. J., Escott-Price, V., Mayeux, R., Deleuze, J. F., Amin, N., Goate, A. M., Pericak-Vance, M. A., Holmans, P. A., Van Duijn, C. M., Ramirez, A., Wang, L. S., Lambert, J. C., Seshadri, S., Williams, J. & Schellenberg, G. D., Sep 1 2017, In : Nature Genetics. 49, 9, p. 1373-1384 12 p.

Research output: Contribution to journalArticle

The Association between Plasma Ceramides and Sphingomyelins and Risk of Alzheimer's Disease Differs by Sex and APOE in the Baltimore Longitudinal Study of Aging

Mielke, M. M., Haughey, N. J., Han, D., An, Y., Bandaru, V. V. R., Lyketsos, C. G., Ferrucci, L. & Resnick, S. M., 2017, In : Journal of Alzheimer's Disease. 60, 3, p. 819-828 10 p.

Research output: Contribution to journalArticle

Baltimore
Sphingomyelins
Ceramides
Longitudinal Studies
Alzheimer Disease

The Mild Behavioral Impairment Checklist (MBI-C): A Rating Scale for Neuropsychiatric Symptoms in Pre-Dementia Populations

Ismail, Z., Agüera-Ortiz, L., Brodaty, H., Cieslak, A., Cummings, J., Fischer, C. E., Gauthier, S., Geda, Y. E., Herrmann, N., Kanji, J., Lanctôt, K. L., Miller, D. S., Mortby, M. E., Onyike, C. U., Rosenberg, P. B., Smith, E. E., Smith, G. S., Sultzer, D. L. & Lyketsos, C., 2017, In : Journal of Alzheimer's Disease. 56, 3, p. 929-938 10 p.

Research output: Contribution to journalArticle

Checklist
Dementia
Research
Population
Behavioral Symptoms

The Prevalence and Specificity of Depression Diagnosis in a Clinic-Based Population of Adults With Type 2 Diabetes Mellitus

Golden, S. H., Shah, N., Naqibuddin, M., Payne, J. L., Hill-Briggs, F., Wand, G. S., Wang, N. Y., Langan, S. & Lyketsos, C., Jan 1 2017, In : Psychosomatics. 58, 1, p. 28-37 10 p.

Research output: Contribution to journalArticle

Depressive Disorder
Type 2 Diabetes Mellitus
Depression
Major Depressive Disorder
Population

Transethnic genome-wide scan identifies novel Alzheimer's disease loci

Jun, G. R. , Chung, J. , Mez, J. , Barber, R. , Beecham, G. W. , Bennett, D. A. , Buxbaum, J. D. , Byrd, G. S. , Carrasquillo, M. M. , Crane, P. K. , Cruchaga, C. , De Jager, P. , Ertekin-Taner, N. , Evans, D. , Fallin, M. D. , Foroud, T. M. , Friedland, R. P. , Goate, A. M. , Graff-Radford, N. R. , Hendrie, H. & 31 others Hall, K. S., Hamilton-Nelson, K. L., Inzelberg, R., Kamboh, M. I., Kauwe, J. S. K., Kukull, W. A., Kunkle, B. W., Kuwano, R., Larson, E. B., Logue, M. W., Manly, J. J., Martin, E. R., Montine, T. J., Mukherjee, S., Naj, A., Reiman, E. M., Reitz, C., Sherva, R., St. George-Hyslop, P. H., Thornton, T., Younkin, S. G., Vardarajan, B. N., Wang, L. S., Wendlund, J. R., Winslow, A. R., Haines, J., Mayeux, R., Pericak-Vance, M. A., Schellenberg, G., Lunetta, K. L. & Farrer, L. A., 2017, (Accepted/In press) In : Alzheimer's and Dementia.

Research output: Contribution to journalArticle

Alzheimer Disease
Genome
Single Nucleotide Polymorphism
Genome-Wide Association Study
Genetic Loci
2016

A Call to Restructure Psychiatry General and Subspecialty Training

Kirwin, P., Conroy, M., Lyketsos, C., Greenwald, B., Forester, B., Devries, C., Ahmed, I. I., Wiechers, I., Zdanys, K., Steffens, D. & Reynolds, C. F., Feb 1 2016, In : Academic Psychiatry. 40, 1, p. 145-148 4 p.

Research output: Contribution to journalArticle

psychiatry
trainee
Psychiatry
certification
Certification

Age at menopause and duration of reproductive period in association with dementia and cognitive function: A systematic review and meta-analysis

Georgakis, M. K., Kalogirou, E. I., Diamantaras, A. A., Daskalopoulou, S. S., Munro, C. A., Lyketsos, C. G., Skalkidou, A. & Petridou, E. T., Nov 1 2016, In : Psychoneuroendocrinology. 73, p. 224-243 20 p.

Research output: Contribution to journalArticle

Menopause
Cognition
Reproduction
Dementia
Meta-Analysis

Alzheimer's disease risk polymorphisms regulate gene expression in the ZCWPW1 and the CELF1 loci

Alzheimer's Disease Genetics Consortium (ADGC), Feb 1 2016, In : PLoS One. 11, 2, e0148717

Research output: Contribution to journalArticle

Genome-Wide Association Study
Alzheimer disease
Polymorphism
Gene expression
Alzheimer Disease

A novel Alzheimer disease locus located near the gene encoding tau protein

Genetic and Environmental Risk in Alzheimer's Disease (GERAD) Consortium & IGAP Consortium, Jan 1 2016, In : Molecular Psychiatry. 21, 1, p. 108-117 10 p.

Research output: Contribution to journalArticle

tau Proteins
Single Nucleotide Polymorphism
Alzheimer Disease
Genes
Exons

A Phase II Study of Fornix Deep Brain Stimulation in Mild Alzheimer's Disease

Lozano, A. M. , Fosdick, L. , Chakravarty, M. M. , Leoutsakos, J. M. , Munro, C. , Oh, E. , Drake, K. E. , Lyman, C. H. , Rosenberg, P. B. , Anderson, W. S. , Tang-Wai, D. F. , Pendergrass, J. C. , Salloway, S. , Asaad, W. F. , Ponce, F. A. , Burke, A. , Sabbagh, M. , Wolk, D. A. , Baltuch, G. , Okun, M. S. & 6 others Foote, K. D., McAndrews, M. P., Giacobbe, P., Targum, S. D., Lyketsos, C. G. & Smith, G. S., Sep 6 2016, In : Journal of Alzheimer's Disease. 54, 2, p. 777-787 11 p.

Research output: Contribution to journalArticle

Brain Fornix
Deep Brain Stimulation
Alzheimer Disease
Glucose
Brain

A population pharmacokinetic model for R- and S-citalopram and desmethylcitalopram in Alzheimer’s disease patients with agitation

Akil, A., Bies, R. R., Pollock, B. G., Avramopoulos, D., Devanand, D. P., Mintzer, J. E., Porsteinsson, A. P., Schneider, L. S., Weintraub, D., Yesavage, J., Shade, D. M. & Lyketsos, C. G., Feb 1 2016, In : Journal of Pharmacokinetics and Pharmacodynamics. 43, 1, p. 99-109 11 p.

Research output: Contribution to journalArticle

Citalopram
Alzheimer Disease
Pharmacokinetics
Population
desmethylcitalopram

Assessment of the genetic variance of late-onset Alzheimer's disease

Alzheimer's Disease Genetics Consortium (ADGC), May 1 2016, In : Neurobiology of Aging. 41, p. 200.e13-200.e20

Research output: Contribution to journalArticle

Alzheimer Disease
Single Nucleotide Polymorphism
Inborn Genetic Diseases
Amyloid beta-Protein Precursor
Myeloid Cells

Bilateral deep brain stimulation of the fornix for Alzheimer's disease: Surgical safety in the ADvance trial

Ponce, F. A., Asaad, W. F., Foote, K. D., Anderson, W. S., Cosgrove, G. R., Baltuch, G. H., Beasley, K., Reymers, D. E., Oh, E. S., Targum, S. D., Smith, G. S., Lyketsos, C. G. & Lozano, A. M., Jul 1 2016, In : Journal of Neurosurgery. 125, 1, p. 75-84 10 p.

Research output: Contribution to journalArticle

Brain Fornix
Deep Brain Stimulation
Alzheimer Disease
Safety
Hospitalization

Case Study: Johns Hopkins Community Health Partnership: A model for transformation

Berkowitz, S. A., Brown, P., Brotman, D. J., Deutschendorf, A., Dunbar, L., Everett, A., Hickman, D., Howell, E., Purnell, L., Sylvester, C., Zollinger, R., Bellantoni, M., Durso, S. C., Lyketsos, C. & Rothman, P., Feb 8 2016, (Accepted/In press) In : Healthcare.

Research output: Contribution to journalArticle

Skilled Nursing Facilities
Health
Patient Care Bundles
Urban Health
Cost of Illness

Citalopram for the Treatment of Agitation in Alzheimer Dementia

Peters, M. E., Vaidya, V., Drye, L. T., Devanand, D. P., Mintzer, J. E., Pollock, B. G., Porsteinsson, A. P., Rosenberg, P. B., Schneider, L. S., Shade, D. M., Weintraub, D., Yesavage, J., Lyketsos, C. G. & Avramopoulos, D., Mar 1 2016, In : Journal of Geriatric Psychiatry and Neurology. 29, 2, p. 59-64 6 p.

Research output: Contribution to journalArticle

Citalopram
Alzheimer Disease
Equipment and Supplies
Therapeutics
Apolipoprotein E2
Alzheimer Disease
Depression
Amyloid Plaques
Geriatrics
Pathology

Closer caregiver and care-recipient relationships predict lower informal costs of dementia care: The Cache County Dementia Progression Study

Rattinger, G. B., Fauth, E. B., Behrens, S., Sanders, C., Schwartz, S., Norton, M. C., Corcoran, C., Mullins, C. D., Lyketsos, C. G. & Tschanz, J. A. T., 2016, (Accepted/In press) In : Alzheimer's and Dementia.

Research output: Contribution to journalArticle

Caregivers
Dementia
Costs and Cost Analysis
Patient Care
Salaries and Fringe Benefits

Editorial: Alzheimer's disease and the fornix

Oishi, K. & Lyketsos, C. G., Jun 23 2016, In : Frontiers in Aging Neuroscience. 8, JUN, 149

Research output: Contribution to journalEditorial

Diffusion Tensor Imaging
Cognition
Alzheimer Disease
Cognitive Dysfunction

Effects of citalopram on neuropsychiatric symptoms in Alzheimer's dementia: Evidence from the CitAD study

For the CitAD Research Group, May 1 2016, In : American Journal of Psychiatry. 173, 5, p. 473-480 8 p.

Research output: Contribution to journalArticle

Citalopram
Alzheimer Disease
Delusions
Hallucinations
Odds Ratio
Health Services
Dementia
Inpatients
Ambulatory Care
Social Welfare

Heterogeneity of treatment response to citalopram for patients with Alzheimer's disease with aggression or agitation: The citad randomized clinical trial

For the CitAD Research Group & Marano, C. M., May 1 2016, In : American Journal of Psychiatry. 173, 5, p. 465-472 8 p.

Research output: Contribution to journalArticle

Citalopram
Aggression
Alzheimer Disease
Randomized Controlled Trials
Therapeutics

Neuropsychiatric symptoms as early manifestations of emergent dementia: Provisional diagnostic criteria for mild behavioral impairment

ISTAART Neuropsychiatric Symptoms Professional Interest Area, Feb 1 2016, In : Alzheimer's and Dementia. 12, 2, p. 195-202 8 p.

Research output: Contribution to journalArticle

Dementia
Neurobehavioral Manifestations
Cognition
Cognitive Dysfunction

Nutritional Status is Associated with Faster Cognitive Decline and Worse Functional Impairment in the Progression of Dementia: The Cache County Dementia Progression Study

Sanders, C., Behrens, S., Schwartz, S., Wengreen, H., Corcoran, C. D., Lyketsos, C. G. & Tschanz, J. T., Apr 26 2016, In : Journal of Alzheimer's Disease. 52, 1, p. 33-42 10 p.

Research output: Contribution to journalArticle

Nutrition Assessment
Nutritional Status
Dementia
Malnutrition
Cognitive Dysfunction

Principal components analysis of agitation outcomes in Alzheimer's disease

For the CitAD Research Group & Drye, L. T., Aug 1 2016, In : Journal of Psychiatric Research. 79, p. 4-7 4 p.

Research output: Contribution to journalArticle

Citalopram
Principal Component Analysis
Alzheimer Disease
Equipment and Supplies
Alzheimer's Disease

R- and S-citalopram concentrations have differential effects on neuropsychiatric scores in elders with dementia and agitation

Ho, T., Pollock, B. G., Mulsant, B. H., Schantz, O., Devanand, D. P., Mintzer, J. E., Porsteinsson, A. P., Schneider, L. S., Weintraub, D., Yesavage, J., Drye, L. T., Munro, C. A., Shade, D. M., Lyketsos, C. & Bies, R., 2016, In : British Journal of Clinical Pharmacology. p. 784-792 9 p.

Research output: Contribution to journalArticle

Citalopram
Area Under Curve
Dementia
Alzheimer Disease
Therapeutics
Caregivers
Dementia
Randomized Controlled Trials
Health Educators
Social Media

Sedation mediates part of Citalopram's effect on agitation in Alzheimer's disease

CitAD Research Group & Drye, L. T., Mar 1 2016, In : Journal of Psychiatric Research. 74, p. 17-21 5 p.

Research output: Contribution to journalArticle

Citalopram
Alzheimer Disease
Placebos
Hypnotics and Sedatives
Canada
Self Care
Type 2 Diabetes Mellitus
Major Depressive Disorder
Depression
Health

WeCareAdvisor™: The Development of a Caregiver-focused, Web-based Program to Assess and Manage Behavioral and Psychological Symptoms of Dementia

Kales, H. C., Gitlin, L. N., Stanislawski, B., Marx, K., Turnwald, M., Watkins, D. C. & Lyketsos, C. G., Nov 15 2016, (Accepted/In press) In : Alzheimer Disease and Associated Disorders.

Research output: Contribution to journalArticle

Behavioral Symptoms
Caregivers
Dementia
Psychology
Licensure
2015

Agitation in cognitive disorders: International Psychogeriatric Association provisional consensus clinical and research definition

Cummings, J., Mintzer, J., Brodaty, H., Sano, M., Banerjee, S., Devanand, D. P., Gauthier, S., Howard, R., Lanctôt, K., Lyketsos, C. G., Peskind, E., Porsteinsson, A. P., Reich, E., Sampaio, C., Steffens, D., Wortmann, M. & Zhong, K., Jan 12 2015, In : International Psychogeriatrics. 27, 1, p. 7-17 11 p.

Research output: Contribution to journalArticle

Consensus
Aggression
Research
Institutionalization
Caregivers
Organizations
Referral and Consultation
Community-Institutional Relations
Independent Living
Baltimore
Caregivers
Dementia
Randomized Controlled Trials
Quality of Life
Depression

Assessment and management of behavioral and psychological symptoms of dementia

Kales, H. C., Gitlin, L. N. & Lyketsos, C. G., Mar 2 2015, In : BMJ (Online). 350, h369

Research output: Contribution to journalArticle

Behavioral Symptoms
Caregivers
Dementia
Psychology
Apathy

Association of long runs of homozygosity with Alzheimer disease among African American individuals

Ghani, M. , Reitz, C. , Cheng, R. , Vardarajan, B. N. , Jun, G. , Sato, C. , Naj, A. , Rajbhandary, R. , Wang, L. S. , Valladares, O. , Lin, C. F. , Larson, E. B. , Graff-Radford, N. R. , Evans, D. , De Jager, P. L. , Crane, P. K. , Buxbaum, J. D. , Murrell, J. R. , Raj, T. , Ertekin-Taner, N. & 153 others Logue, M., Baldwin, C. T., Green, R. C., Barnes, L. L., Cantwell, L. B., Fallin, M. D., Go, R. C. P., Griffith, P. A., Obisesan, T. O., Manly, J. J., Lunetta, K. L., Kamboh, M. I., Lopez, O. L., Bennett, D. A., Hendrie, H., Hall, K. S., Goate, A. M., Byrd, G. S., Kukull, W. A., Foroud, T. M., Haines, J. L., Farrer, L. A., Pericak-Vance, M. A., Lee, J. H., Schellenberg, G. D., St. George-Hyslop, P., Mayeux, R., Rogaeva, E., Albert, M. S., Albin, R. L., Apostolova, L. G., Arnold, S. E., Barber, R., Barmada, M. M., Beach, T. G., Beecham, G. W., Beekly, D., Bigio, E. H., Bird, T. D., Blacker, D., Boeve, B. F., Bowen, J. D., Boxer, A., Burke, J. R., Cai, G., Cairns, N. J., Cao, C., Carlson, C. S., Carney, R. M., Carroll, S. L., Chui, H. C., Clark, D. G., Cribbs, D. H., Crocco, E. A., Cruchaga, C., DeCarli, C., DeKosky, S. T., Demirci, F. Y., Dick, M., Faber, K. M., Fallon, K. B., Ferris, S., Frosch, M. P., Galasko, D. R., Ganguli, M., Gearing, M., Geschwind, D. H., Ghetti, B., Gilbert, J. R., Gilman, S., Glass, J. D., Growdon, J. H., Hakonarson, H., Hamilton, R. L., Hamilton-Nelson, K. L., Haroutunian, V., Harrell, L. E., Honig, L. S., Hulette, C. M., Hyman, B. T., Jarvik, G. P., Jicha, G. A., Jin, L. W., Karydas, A., Kauwe, J. S. K., Kaye, J. A., Kim, R., Koo, E. H., Kowall, N. W., Kramer, J. H., Kramer, P., LaFerla, F. M., Lah, J. J., Lang-Walker, R., Leverenz, J. B., Levey, A. I., Li, G., Lieberman, A. P., Lyketsos, C. G., Mack, W. J., Marson, D. C., Martiniuk, F., Mash, D. C., Masliah, E., McCormick, W. C., McCurry, S. M., McDavid, A. N., McKee, A. C., Mesulam, M., Miller, B. L., Miller, C. A., Miller, J. W., Montine, T. J., Morris, J. C., Olichney, J. M., Parisi, J. E., Peskind, E., Petersen, R. C., Pierce, A., Poon, W. W., Potter, H., Quinn, J. F., Raj, A., Raskind, M., Reiman, E. M., Reisberg, B., Ringman, J. M., Roberson, E. D., Sano, M., Saykin, A. J., Schneider, J. A., Schneider, L. S., Seeley, W. W., Smith, A. G., Sonnen, J. A., Spina, S., Stern, R. A., Tanzi, R. E., Trojanowski, J. Q., Troncoso, J. C., Tsuang, D. W., Van Deerlin, V. M., Van Eldik, L. J., Vinters, H. V., Vonsattel, J. P., Weintraub, S., Welsh-Bohmer, K. A., Williamson, J., Woltjer, R. L., Wright, C. B., Younkin, S. G., Yu, C. E. & Yu, L., Nov 1 2015, In : JAMA Neurology. 72, 11, p. 1313-1323 11 p.

Research output: Contribution to journalArticle

African Americans
Alzheimer Disease
Single Nucleotide Polymorphism
Consensus
Dementia

Associations between Potentially Modifiable Risk Factors and Alzheimer Disease: A Mendelian Randomization Study

Alzheimer’s Disease Genetics Consortium, The GERAD1 Consortium & EPIC-InterAct Consortium, Jun 1 2015, In : PLoS Medicine. 12, 6, e1001841

Research output: Contribution to journalArticle

Random Allocation
Single Nucleotide Polymorphism
Alzheimer Disease
Blood pressure
Smoking

Atlas-based diffusion tensor imaging correlates of executive function

Nowrangi, M. A., Okonkwo, O., Lyketsos, C., Oishi, K., Mori, S., Albert, M. & Mielke, M. M., 2015, In : Journal of Alzheimer's Disease. 44, 2, p. 585-598 14 p.

Research output: Contribution to journalArticle

Diffusion Tensor Imaging
Atlases
Executive Function
Anisotropy
Alzheimer Disease

Beyond memory: A focus on the other neuropsychiatric symptoms of dementia

Peters, M. E. & Lyketsos, C. G., Feb 1 2015, In : American Journal of Geriatric Psychiatry. 23, 2, p. 115-118 4 p.

Research output: Contribution to journalArticle

Mental Disorders
Dementia

Caregiver report versus clinician impression: Disagreements in rating neuropsychiatric symptoms in Alzheimer's disease patients

Stella, F., Forlenza, O. V., Laks, J., De Andrade, L. P., De Castilho Cação, J., Govone, J. S., De Medeiros, K. & Lyketsos, C. G., Dec 1 2015, In : International Journal of Geriatric Psychiatry. 30, 12, p. 1230-1237 8 p.

Research output: Contribution to journalArticle

Caregivers
Alzheimer Disease
Dementia
Depression
Apathy

Change in agitation in Alzheimer's disease in the placebo arm of a nine-week controlled trial

Rosenberg, P. B., Drye, L. T., Porsteinsson, A. P., Pollock, B. G., Devanand, D. P., Frangakis, C., Ismail, Z., Marano, C., Meinert, C. L., Mintzer, J. E., Munro, C. A., Pelton, G., Rabins, P. V., Schneider, L. S., Shade, D. M., Weintraub, D., Newell, J., Yesavage, J. & Lyketsos, C. G., Dec 1 2015, In : International Psychogeriatrics. 27, 12, p. 2059-2067 9 p.

Research output: Contribution to journalArticle

Alzheimer Disease
Placebos
Equipment and Supplies
Citalopram
Activities of Daily Living

Deep brain stimulation targeting the fornix for mild Alzheimer dementia: Design of the ADvance randomized controlled trial

Holroyd, K. B. , Fosdick, L. , Smith, G. S. , Leoutsakos, J. M. , Munro, C. A. , Oh, E. S. , Drake, K. E. , Rosenberg, P. B. , Anderson, W. S. , Salloway, S. , Pendergrass, J. C. , Burke, A. D. , Wolk, D. A. , Tang-Wai, D. F. , Ponce, F. A. , Asaad, W. F. , Sabbagh, M. N. , Okun, M. S. , Baltuch, G. , Foote, K. D. & 3 others Targum, S. D., Lozano, A. M. & Lyketsos, C. G., Jul 10 2015, In : Open Access Journal of Clinical Trials. 7, p. 63-76 14 p.

Research output: Contribution to journalArticle

Deep Brain Stimulation
Alzheimer Disease
Randomized Controlled Trials
Dementia
Brain Fornix

Delirium

Heffernan, S. P., Oh, E., Lyketsos, C. & Neufeld, K., Jan 20 2015, Troublesome Disguises: Managing Challenging Disorders in Psychiatry: Second Edition. Wiley Blackwell, p. 186-198 13 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Delirium
Psychiatry
Diagnostic Errors
Consciousness
Cognition

Dementia caregivers coping strategies and their relationship to health and well-being: The Cache County Study

Snyder, C. M., Fauth, E., Wanzek, J., Piercy, K. W., Norton, M. C., Corcoran, C., Rabins, P. V., Lyketsos, C. G. & Tschanz, J. T., Jan 1 2015, In : Aging and Mental Health. 19, 5, p. 390-399 10 p.

Research output: Contribution to journalArticle

Caregivers
Dementia
Health
Anxiety
Equipment and Supplies