Find Research Outputs

Search concepts
Selected Filters
2017

APOE Genotype and Nonrespiratory Sleep Parameters in Cognitively Intact Older Adults

Spira, A. P., An, Y., Peng, Y., Wu, M. N., Simonsick, E. M., Ferrucci, L. & Resnick, S. M. Aug 1 2017 In : Sleep. 40, 8

Research output: Research - peer-reviewArticle

Apolipoproteins E
Sleep
Genotype
Odds Ratio
Confidence Intervals

Association of Hearing Impairment and Anxiety in Older Adults

Contrera, K. J., Betz, J., Deal, J., Choi, J. S., Ayonayon, H. N., Harris, T., Helzner, E., Martin, K. R., Mehta, K., Pratt, S., Rubin, S. M., Satterfield, S., Yaffe, K., Simonsick, E. M. & Lin, F. R. Feb 1 2017 In : Journal of Aging and Health. 29, 1, p. 172-184 13 p.

Research output: Research - peer-reviewArticle

Hearing Loss
Anxiety
Logistic Models
Odds Ratio
Confidence Intervals

Circulating vitamin K is inversely associated with incident cardiovascular disease risk among those treated for hypertension in the health, aging, and body composition study (Health ABC)

Shea, M. K., Booth, S. L., Weiner, D. E., Brinkley, T. E., Kanaya, A. M., Murphy, R. A., Simonsick, E. M., Wassel, C. L., Vermeer, C., Kritchevsky, S. B. & The Health ABC Study 2017 In : Journal of Nutrition. 147, 5, p. 888-895 8 p.

Research output: Research - peer-reviewArticle

Vitamin K
Body Composition
Cardiovascular Diseases
Hypertension
Health

Compensatory Saccades Are Associated with Physical Performance in Older Adults: Data from the Baltimore Longitudinal Study of Aging

Xie, Y., Anson, E. R., Simonsick, E. M., Studenski, S. A. & Agrawal, Y. Mar 1 2017 In : Otology and Neurotology. 38, 3, p. 373-378 6 p.

Research output: Research - peer-reviewArticle

Baltimore
Saccades
Longitudinal Studies
Vestibulo-Ocular Reflex
Odds Ratio

Contributions to lateral balance control in ambulatory older adults

Sparto, P. J., Newman, A. B., Simonsick, E. M., Caserotti, P., Strotmeyer, E. S., Kritchevsky, S. B., Yaffe, K., Rosano, C. & For The Health Abc Study Aug 23 2017 (Accepted/In press) In : Aging Clinical and Experimental Research. p. 1-9 9 p.

Research output: Research - peer-reviewArticle

Executive Function
Pressure
Lower Extremity
Linear Models
Accidental Falls

Hearing impairment and incident dementia and cognitive decline in older adults: The health ABC study

Deal, J. A., Betz, J., Yaffe, K., Harris, T., Purchase-Helzner, E., Satterfield, S., Pratt, S., Govil, N., Simonsick, E. M., Lin, F. R. & For The Health Abc Study Group 2017 In : Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 72, 5, p. 703-709 7 p.

Research output: Research - peer-reviewArticle

Hearing Loss
Dementia
Health
Cognitive Dysfunction
Hearing

Impact of Incident Heart Failure on Body Composition Over Time in the Health, Aging, and Body Composition Study Population

Forman, D. E., Santanasto, A. J., Boudreau, R., Harris, T., Kanaya, A. M., Satterfield, S., Simonsick, E. M., Butler, J., Kizer, J. R. & Newman, A. B. Sep 1 2017 In : Circulation. Heart failure. 10, 9

Research output: Research - peer-reviewArticle

Body Composition
Heart Failure
Health
Population
Cohort Studies

Long-term changes in time spent walking and subsequent cognitive and structural brain changes in older adults

Best, J. R., Rosano, C., Aizenstein, H. J., Tian, Q., Boudreau, R. M., Ayonayon, H. N., Satterfield, S., Simonsick, E. M., Studenski, S., Yaffe, K. & Liu-Ambrose, T. Sep 1 2017 In : Neurobiology of Aging. 57, p. 153-161 9 p.

Research output: Research - peer-reviewArticle

Walking
Brain
Cognition
Maintenance
White Matter

Lower mitochondrial energy production of the thigh muscles in patients with low-normal ankle-brachial index

AlGhatrif, M., Zane, A., Oberdier, M., Canepa, M., Studenski, S., Simonsick, E., Spencer, R. G., Fishbein, K., Reiter, D., Lakatta, E. G., McDermott, M. M. & Ferrucci, L. Sep 1 2017 In : Journal of the American Heart Association. 6, 9, e006604

Research output: Research - peer-reviewArticle

Ankle Brachial Index
Thigh
Muscles
Phosphocreatine
Exercise

Metabolites Associated with Lean Mass and Adiposity in Older Black Men

Murphy, R. A., Moore, S. C., Playdon, M., Meirelles, O., Newman, A. B., Milijkovic, I., Kritchevsky, S. B., Schwartz, A., Goodpaster, B. H., Sampson, J., Cawthon, P., Simonsick, E. M., Gerszten, R. E., Clish, C. B. & Harris, T. B. Oct 1 2017 In : Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 72, 10, p. 1352-1359 8 p.

Research output: Research - peer-reviewArticle

Adiposity
Fats
Body Mass Index
Body Composition
Amino Acids

Muscle fatigability and depressive symptoms in later life

Brown, P. J., Badreddine, D., Roose, S. P., Rutherford, B., Ayonayon, H. N., Yaffe, K., Simonsick, E. M. & Goodpaster, B. 2017 (Accepted/In press) In : International Journal of Geriatric Psychiatry.

Research output: Research - peer-reviewArticle

Depression
Muscles
Epidemiologic Studies
Body Composition
Proportional Hazards Models

Muscle strength mediates the relationship between mitochondrial energetics and walking performance

Zane, A. C., Reiter, D. A., Shardell, M., Cameron, D., Simonsick, E. M., Fishbein, K. W., Studenski, S. A., Spencer, R. G. & Ferrucci, L. 2017 (Accepted/In press) In : Aging Cell.

Research output: Research - peer-reviewArticle

Muscle Strength
Walking
Muscles
Knee
Walking Speed

Olfaction and risk of dementia in a biracial cohort of older adults

Yaffe, K., Freimer, D., Chen, H., Asao, K., Rosso, A., Rubin, S., Tranah, G., Cummings, S. & Simonsick, E. Jan 31 2017 In : Neurology. 88, 5, p. 456-462 7 p.

Research output: Research - peer-reviewArticle

Smell
Dementia
Odorants
Confidence Intervals
hydroquinone

Potential drug-drug and drug-disease interactions in well-functioning community-dwelling older adults

Hanlon, J. T., Perera, S., Newman, A. B., Thorpe, J. M., Donohue, J. M., Simonsick, E. M., Shorr, R. I., Bauer, D. C. & Marcum, Z. A. 2017 (Accepted/In press) In : Journal of Clinical Pharmacy and Therapeutics.

Research output: Research - peer-reviewArticle

Independent Living
Drug Interactions
Pharmaceutical Preparations
Odds Ratio
Confidence Intervals

Relationship between sensorimotor peripheral nerve function and indicators of cardiovascular autonomic function in older adults from the Health, Aging and Body Composition Study

Lange-Maia, B. S., Newman, A. B., Jakicic, J. M., Cauley, J. A., Boudreau, R. M., Schwartz, A. V., Simonsick, E. M., Satterfield, S., Vinik, A. I., Zivkovic, S., Harris, T. B. & Strotmeyer, E. S. Oct 1 2017 In : Experimental Gerontology. 96, p. 38-45 8 p.

Research output: Research - peer-reviewArticle

Body Composition
Peripheral Nerves
Heart Rate
Health
Aging of materials

The association between subclinical thyroid dysfunction and dementia: The Health, Aging and Body Composition (Health ABC) Study

Aubert, C. E., Bauer, D. C., da Costa, B. R., Feller, M., Rieben, C., Simonsick, E. M., Yaffe, K., Rodondi, N. & the Health ABC Study Nov 1 2017 In : Clinical Endocrinology. 87, 5, p. 617-626 10 p.

Research output: Research - peer-reviewArticle

Body Composition
Dementia
Thyroid Gland
Health
Hyperthyroidism
Thyroid Gland
Mortality
Phenotype
Thyroid Hormones
Confidence Intervals

Vitamin B12 and homocysteine associations with gait speed in older adults: The Baltimore Longitudinal Study of Aging

Vidoni, M. L., Pettee Gabriel, K., Luo, S. T., Simonsick, E. M. & Day, R. S. Feb 28 2017 (Accepted/In press) In : Journal of Nutrition, Health and Aging. p. 1-8 8 p.

Research output: Research - peer-reviewArticle

Baltimore
Homocysteine
Vitamin B 12
Longitudinal Studies
Walking Speed
2016

31P magnetic resonance spectroscopy assessment of muscle bioenergetics as a predictor of gait speed in the Baltimore longitudinal study of aging

Choi, S., Reiter, D. A., Shardell, M., Simonsick, E. M., Studenski, S., Spencer, R. G., Fishbein, K. W. & Ferrucci, L. 2016 In : Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 71, 12, p. 1638-1645 8 p.

Research output: Research - peer-reviewArticle

Baltimore
Energy Metabolism
Longitudinal Studies
Magnetic Resonance Spectroscopy
Muscles

Age-related change in mobility: Perspectives from life course epidemiology and geroscience

Ferrucci, L., Cooper, R., Shardell, M., Simonsick, E. M., Schrack, J. A. & Kuh, D. Sep 1 2016 In : Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 71, 9, p. 1184-1194 11 p.

Research output: Research - peer-reviewReview article

Epidemiology
Exercise
Mobility Limitation
Aptitude
Genetic Selection

Agreement and Predictive Validity Using Less-Conservative Foundation for the National Institutes of Health Sarcopenia Project Weakness Cutpoints

Chiles Shaffer, N., Ferrucci, L., Shardell, M., Simonsick, E. M. & Studenski, S. 2016 (Accepted/In press) In : Journal of the American Geriatrics Society.

Research output: Research - peer-reviewArticle

Sarcopenia
National Institutes of Health (U.S.)
Walking
Confidence Intervals
Baltimore

An evaluation of the longitudinal, bidirectional associations between gait speed and cognition in older women and men

Best, J. R., Liu-Ambrose, T., Boudreau, R. M., Ayonayon, H. N., Satterfield, S., Simonsick, E. M., Studenski, S., Yaffe, K., Newman, A. B. & Rosano, C. 2016 In : Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 71, 12, p. 1616-1623 8 p.

Research output: Research - peer-reviewArticle

Cognition
Walking Speed
Exercise
Independent Living
Cohort Studies

Ankle Proprioception Associated Gait Patterns in Older Adults: Results from the BLSA

Ko, S. U., Simonsick, E. M., Despande, N., Studenski, S. & Ferrucci, L. Jun 20 2016 (Accepted/In press) In : Medicine and Science in Sports and Exercise.

Research output: Research - peer-reviewArticle

Proprioception
Baltimore
Gait
Ankle
Longitudinal Studies

Ankle proprioceptive acuity is associated with objective as well as self-report measures of balance, mobility, and physical function

Deshpande, N., Simonsick, E., Metter, E. J., Ko, S., Ferrucci, L. & Studenski, S. Jun 1 2016 In : Age. 38, 3, 53

Research output: Research - peer-reviewArticle

Ankle
Self Report
Proprioception
Ankle Joint
Leg

Antidepressant Use and Recurrent Falls in Community-Dwelling Older Adults: Findings From the Health ABC Study

Marcum, Z. A., Perera, S., Thorpe, J. M., Switzer, G. E., Castle, N. G., Strotmeyer, E. S., Simonsick, E. M., Ayonayon, H. N., Phillips, C. L., Rubin, S., Zucker-Levin, A. R., Bauer, D. C., Shorr, R. I., Kang, Y., Gray, S. L. & Hanlon, J. T. Jul 1 2016 In : Annals of Pharmacotherapy. 50, 7, p. 525-533 9 p.

Research output: Research - peer-reviewArticle

Independent Living
Antidepressive Agents
Health
Odds Ratio
Serotonin Uptake Inhibitors

Apical periodontitis and incident cardiovascular events in the Baltimore Longitudinal Study of Ageing

Gomes, M. S., Hugo, F. N., Hilgert, J. B., Sant'Ana Filho, M., Padilha, D. M. P., Simonsick, E. M., Ferrucci, L. & Reynolds, M. A. Apr 1 2016 In : International Endodontic Journal. 49, 4, p. 334-342 9 p.

Research output: Research - peer-reviewArticle

Periapical Periodontitis
Baltimore
Endodontics
Longitudinal Studies
Therapeutics

Apolipoprotein e allele and hearing thresholds in older adults

Mener, D. J., Betz, J., Yaffe, K., Harris, T. B., Helzner, E. P., Satterfield, S., Houston, D. K., Strotmeyer, E. S., Pratt, S. R., Simonsick, E. M. & Lin, F. R. Feb 1 2016 In : American Journal of Alzheimer's Disease and other Dementias. 31, 1, p. 34-39 6 p.

Research output: Research - peer-reviewArticle

Apolipoproteins
Hearing
Alleles
Apolipoprotein E4
Apolipoproteins E

Association Between Accelerated Multimorbidity and Age-Related Cognitive Decline in Older Baltimore Longitudinal Study of Aging Participants without Dementia

Fabbri, E., An, Y., Zoli, M., Tanaka, T., Simonsick, E. M., Kitner-Triolo, M. H., Studenski, S. A., Resnick, S. M. & Ferrucci, L. May 1 2016 In : Journal of the American Geriatrics Society. 64, 5, p. 965-972 8 p.

Research output: Research - peer-reviewArticle

Baltimore
Longitudinal Studies
Dementia
Comorbidity
Chronic Disease

Association between race, household income and grip strength in middleand older-Aged adults

Thorpe, R. J., Simonsick, E., Zonderman, A. & Evans, M. K. Sep 1 2016 In : Ethnicity and Disease. 26, 4, p. 493-500 8 p.

Research output: Research - peer-reviewArticle

Hand Strength
African Americans
Poverty
Sarcopenia
Insurance Coverage

Association of Hearing Impairment and Emotional Vitality in Older Adults

Contrera, K. J., Betz, J., Deal, J. A., Choi, J. S., Ayonayon, H. N., Harris, T., Helzner, E., Martin, K. R., Mehta, K., Pratt, S., Rubin, S. M., Satterfield, S., Yaffe, K., Garcia, M., Simonsick, E. M. & Lin, F. R. May 1 2016 In : Journals of Gerontology - Series B Psychological Sciences and Social Sciences. 71, 3, p. 400-404 5 p.

Research output: Research - peer-reviewArticle

Hearing Loss
Hearing Aids
Mental Health
Odds Ratio
Confidence Intervals

Basal body temperature as a biomarker of healthy aging

Simonsick, E. M., Meier, H. C. S., Shaffer, N. C., Studenski, S. A. & Ferrucci, L. Oct 26 2016 (Accepted/In press) In : Age. p. 1-10 10 p.

Research output: Research - peer-reviewArticle

Body Temperature
Biomarkers
Temperature
Adiposity
Walking Speed

Chronic low-calorie sweetener use and risk of abdominal obesity among older adults: A cohort study

Chia, C. W., Shardell, M., Tanaka, T., Liu, D. D., Gravenstein, K. S., Simonsick, E. M., Egan, J. M. & Ferrucci, L. Nov 1 2016 In : PLoS One. 11, 11, e0167241

Research output: Research - peer-reviewArticle

sweeteners
cohort studies
obesity
Sweetening Agents
Abdominal Obesity

Circulating ceramides are inversely associated with cardiorespiratory fitness in participants aged 54–96 years from the Baltimore Longitudinal Study of Aging

Fabbri, E., Yang, A., Simonsick, E. M., Chia, C. W., Zoli, M., Haughey, N. J., Mielke, M. M., Ferrucci, L. & Coen, P. M. Oct 1 2016 In : Aging Cell. 15, 5, p. 825-831 7 p.

Research output: Research - peer-reviewArticle

Baltimore
Ceramides
Longitudinal Studies
Cardiorespiratory Fitness
Health

Cross-sectional and longitudinal associations between adiposity and walking endurance in adults age 60-79

Jerome, G. J., Ko, S. U., Chiles Shaffer, N. S., Studenski, S. A., Ferrucci, L. & Simonsick, E. M. 2016 In : Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 71, 12, p. 1661-1666 6 p.

Research output: Research - peer-reviewArticle

Adiposity
Walking
Weights and Measures
Body Mass Index
Fats

Depressive Trajectories and Risk of Disability and Mortality in Older Adults: Longitudinal Findings from the Health, Aging, and Body Composition Study

Murphy, R. A., Hagaman, A. K., Reinders, I., Steeves, J. A., Newman, A. B., Rubin, S. M., Satterfield, S., Kritchevsky, S. B., Yaffe, K., Ayonayon, H. N., Nagin, D. S., Simonsick, E. M., Penninx, B. W. J. H. & Harris, T. B. Feb 1 2016 In : Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 71, 2, p. 228-235 8 p.

Research output: Research - peer-reviewArticle

Body Composition
Mortality
Health
Depression
Confidence Intervals

Does Sensory Function Decline Independently or Concomitantly with Age? Data from the Baltimore Longitudinal Study of Aging

Gadkaree, S. K., Sun, D. Q., Li, C., Lin, F. R., Ferrucci, L., Simonsick, E. M. & Agrawal, Y. 2016 In : Journal of Aging Research. 2016, 1865038

Research output: Research - peer-reviewArticle

Vestibular Evoked Myogenic Potentials
Social Adjustment
Proprioception
Baltimore
Ankle Joint

Effects of aromatase inhibition vs. testosterone in older men with low testosterone: randomized-controlled trial

Dias, J. P., Melvin, D., Simonsick, E. M., Carlson, O., Shardell, M. D., Ferrucci, L., Chia, C. W., Basaria, S. & Egan, J. M. Jan 1 2016 In : Andrology. 4, 1, p. 33-40 8 p.

Research output: Research - peer-reviewArticle

Aromatase
Bone Density
Testosterone
Randomized Controlled Trials
Body Composition

Exercise Capacity, Heart Failure Risk, and Mortality in Older Adults: The Health ABC Study

Georgiopoulou, V. V., Kalogeropoulos, A. P., Chowdhury, R., Binongo, J. N. G., Bibbins-Domingo, K., Rodondi, N., Simonsick, E. M., Harris, T., Newman, A. B., Kritchevsky, S. B. & Butler, J. 2016 (Accepted/In press) In : American Journal of Preventive Medicine.

Research output: Research - peer-reviewArticle

Heart Failure
Exercise
Mortality
Health
Walk Test

Fatigued, but Not Frail: Perceived Fatigability as a Marker of Impending Decline in Mobility-Intact Older Adults

Simonsick, E. M., Glynn, N. W., Jerome, G. J., Shardell, M., Schrack, J. A. & Ferrucci, L. Jun 1 2016 In : Journal of the American Geriatrics Society. 64, 6, p. 1287-1292 6 p.

Research output: Research - peer-reviewArticle

Walking
Walking Speed
Baltimore
Body Composition
Longitudinal Studies
Baltimore
Aptitude
Thyroxine
Walking
Fatigue

Impact of Drug–Drug and Drug–Disease Interactions on Gait Speed in Community-Dwelling Older Adults

Naples, J. G., Marcum, Z. A., Perera, S., Newman, A. B., Greenspan, S. L., Gray, S. L., Bauer, D. C., Simonsick, E. M., Shorr, R. I. & Hanlon, J. T. Apr 30 2016 (Accepted/In press) In : Drugs & Aging. p. 1-8 8 p.

Research output: Research - peer-reviewArticle

Independent Living
Drug Interactions
Pharmaceutical Preparations
Walking Speed
Odds Ratio

Inflammation, Depression, and Slow Gait: A High Mortality Phenotype in Later Life

Brown, P. J., Roose, S. P., Zhang, J., Wall, M., Rutherford, B. R., Ayonayon, H. N., Butters, M. A., Harris, T., Newman, A. B., Satterfield, S., Simonsick, E. M. & Yaffe, K. Feb 1 2016 In : Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 71, 2, p. 221-227 7 p.

Research output: Research - peer-reviewArticle

Gait
Inflammation
Phenotype
Mortality
Body Composition

Lower gray matter integrity is associated with greater lap time variation in high-functioning older adults

Tian, Q., Resnick, S. M., Landman, B. A., Huo, Y., Venkatraman, V. K., Gonzalez, C. E., Simonsick, E. M., Shardell, M. D., Ferrucci, L. & Studenski, S. A. May 1 2016 In : Experimental Gerontology. 77, p. 46-51 6 p.

Research output: Research - peer-reviewArticle

Gray Matter
Gait
Diffusion tensor imaging
Medical problems
Aging of materials

Restricted activity and persistent pain following motor vehicle collision among older adults: A multicenter prospective cohort study

Platts-Mills, T. F., Nicholson, R. J., Richmond, N. L., Patel, K. V., Simonsick, E. M., Domeier, R. M., Swor, R. A., Hendry, P. L., Peak, D. A., Rathlev, N. K., Jones, J. S., Lee, D. C., Weaver, M. A., Keefe, F. J. & McLean, S. A. 2016 In : BMC Geriatrics. 16, 1, 86

Research output: Research - peer-reviewArticle

Motor Vehicles
Cohort Studies
Prospective Studies
Exercise
Pain
Walking
Costs and Cost Analysis
Walking Speed
Gait
Linear Models

SARC-F: A symptom score to predict persons with sarcopenia at risk for poor functional outcomes

Malmstrom, T. K., Miller, D. K., Simonsick, E. M., Ferrucci, L. & Morley, J. E. Mar 1 2016 In : Journal of Cachexia, Sarcopenia and Muscle. 7, 1, p. 28-36 9 p.

Research output: Research - peer-reviewArticle

Sarcopenia
Baltimore
Nutrition Surveys
Principal Component Analysis
African Americans

Sensorimotor peripheral nerve function and the longitudinal relationship with endurance walking in the health, aging and body composition study

Lange-Maia, B. S., Newman, A. B., Cauley, J. A., Boudreau, R. M., Jakicic, J. M., Caserotti, P., Glynn, N. W., Harris, T. B., Kritchevsky, S. B., Schwartz, A. V., Satterfield, S., Simonsick, E. M., Vinik, A. I., Zivkovic, S. & Strotmeyer, E. S. Jan 1 2016 In : Archives of Physical Medicine and Rehabilitation. 97, 1, p. 45-52 8 p.

Research output: Research - peer-reviewArticle

Vibration
Body Composition
Peripheral Nerves
Walking
Lower Extremity

Sleep duration and subsequent cortical thinning in cognitively normal older adults

Spira, A. P., Gonzalez, C. E., Venkatraman, V. K., Wu, M. N., Pacheco, J., Simonsick, E. M., Ferrucci, L. & Resnick, S. M. May 1 2016 In : Sleep. 39, 5, p. 1121-1128 8 p.

Research output: Research - peer-reviewArticle

Sleep
Magnetic Resonance Imaging
Prefrontal Cortex
Occipital Lobe
Temporal Lobe

Trajectories of depressive symptoms in older adults and risk of dementia

Kaup, A. R., Byers, A. L., Falvey, C., Simonsick, E. M., Satterfield, S., Ayonayon, H. N., Smagula, S. F., Rubin, S. M. & Yaffe, K. May 1 2016 In : JAMA Psychiatry. 73, 5, p. 525-531 7 p.

Research output: Research - peer-reviewArticle

Dementia
Depression
Symptom Assessment
Incidence
Health

Vitamin K Status and Lower Extremity Function in Older Adults: The Health Aging and Body Composition Study

Shea, M. K., Loeser, R. F., Hsu, F. C., Booth, S. L., Nevitt, M., Simonsick, E. M., Strotmeyer, E. S., Vermeer, C. & Kritchevsky, S. B. Oct 1 2016 In : Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 71, 10, p. 1348-1355 8 p.

Research output: Research - peer-reviewArticle

Vitamin K
Body Composition
Lower Extremity
Health
Vitamin K 1