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Review article

Targeting Epidermal Growth Factor Receptor in triple negative breast cancer: New discoveries and practical insights for drug development

Costa, R., Shah, A. N., Santa-Maria, C., Cruz, M. R., Mahalingam, D., Carneiro, B. A., Chae, Y. K., Cristofanilli, M., Gradishar, W. J. & Giles, F. J., Feb 1 2017, In : Cancer Treatment Reviews. 53, p. 111-119 9 p.

Research output: Contribution to journalReview article

Targeting Errors in the ICU: Use of a National Database

Kleinpell, R., Thompson, D., Kelso, L. & Pronovost, P. J., Dec 1 2006, In : Critical care nursing clinics of North America. 18, 4, p. 509-514 6 p.

Research output: Contribution to journalReview article

Targeting exercise interventions to patients with cancer in need: An individual patient data meta-analysis

Sweegers, M. G., May, A. M., Chinapaw, M. J., Van Vulpen, J. K., Newton, R. U., Galvão, D. A., Aaronson, N. K., Stuiver, M. M., Jacobsen, P. B., Verdonck-De Leeuw, I. M., Steindorf, K., Irwin, M. L., Hayes, S., Griffith, K. A., Lucia, A., Herrero-Roman, F., Mesters, I., Van Weert, E., Knoop, H., Goedendorp, M. M. & 29 others, Mutrie, N., Daley, A. J., McConnachie, A., Bohus, M., Thorsen, L., Schulz, K. H., Short, C. E., James, E. L., Plotnikoff, R. C., Arbane, G., Schmidt, M. E., Potthoff, K., Van Beurden, M., Oldenburg, H. S., Sonke, G. S., Van Harten, W. H., Garrod, R., Schmitz, K. H., Winters-Stone, K. M., Velthuis, M. J., Taaffe, D. R., Van Mechelen, W., Kersten, M. J., Nollet, F., Wenzel, J., Wiskemann, J., Brug, J., Courneya, K. S. & Buffart, L. M., 2018, In : Journal of the National Cancer Institute. 110, 11, djy161.

Research output: Contribution to journalReview article

Targeting extra-articular manifestations in PsA: A closer look at enthesitis and dactylitis

Siegel, E. L., Orbai, A. M. & Ritchlin, C. T., Mar 6 2015, In : Current opinion in rheumatology. 27, 2, p. 111-117 7 p.

Research output: Contribution to journalReview article

Targeting fanconi anemia/BRCA2 pathway defects in cancer: The significance of preclinical pharmacogenomic models

Gallmeier, E. & Kern, S. E., Jan 1 2007, In : Clinical Cancer Research. 13, 1, p. 4-10 7 p.

Research output: Contribution to journalReview article

Targeting fibronectin for cancer imaging and therapy

Han, Z. & Lu, Z. R., Jan 1 2017, In : Journal of Materials Chemistry B. 5, 4, p. 639-654 16 p.

Research output: Contribution to journalReview article

Targeting FLT3 mutations in AML: review of current knowledge and evidence

Daver, N., Schlenk, R. F., Russell, N. H. & Levis, M. J., Feb 1 2019, In : Leukemia. 33, 2, p. 299-312 14 p.

Research output: Contribution to journalReview article

Targeting FLT3 to treat leukemia

Konig, H. & Levis, M., Jan 1 2015, In : Expert opinion on therapeutic targets. 19, 1, p. 37-54 18 p.

Research output: Contribution to journalReview article

Targeting HIF-1 for cancer therapy

Semenza, G. L., Oct 2003, In : Nature Reviews Cancer. 3, 10, p. 721-732 12 p.

Research output: Contribution to journalReview article

Targeting HIV latency: Pharmacologic strategies toward eradication

Xing, S. & Siliciano, R. F., Jun 1 2013, In : Drug Discovery Today. 18, 11-12, p. 541-551 11 p.

Research output: Contribution to journalReview article

Targeting human epidermal growth factor receptor 2 (HER2) in gynecologic malignancies

Erickson, B. K., Zeybek, B., Santin, A. D. & Fader, A. N., Feb 1 2020, In : Current Opinion in Obstetrics and Gynecology. 32, 1, p. 57-64 8 p.

Research output: Contribution to journalReview article

Targeting IGF-1R in the treatment of sarcomas: Past, present and future

Su, Y. K., Wan, X. & Helman, L. J., Jul 1 2009, In : Bulletin du Cancer. 96, 7-8, p. E52-E60

Research output: Contribution to journalReview article

Targeting lipid biosynthesis and salvage in apicomplexan parasites for improved chemotherapies

Coppens, I., Dec 1 2013, In : Nature Reviews Microbiology. 11, 12, p. 823-835 13 p.

Research output: Contribution to journalReview article

Targeting lymphatic function as a novel therapeutic intervention for rheumatoid arthritis

Bouta, E. M., Bell, R. D., Rahimi, H., Xing, L., Wood, R. W., Bingham, C., Ritchlin, C. T. & Schwarz, E. M., Feb 1 2018, In : Nature Reviews Rheumatology. 14, 2, p. 94-106 13 p.

Research output: Contribution to journalReview article

Targeting mediators of vascular injury in scleroderma

Schachna, L. & Wigley, F. M., Nov 1 2002, In : Current opinion in rheumatology. 14, 6, p. 686-693 8 p.

Research output: Contribution to journalReview article

Targeting metabolism as a novel therapeutic approach to autoimmunity, inflammation, and transplantation

Bettencourt, I. A. & Powell, J., Feb 1 2017, In : Journal of Immunology. 198, 3, p. 999-1005 7 p.

Research output: Contribution to journalReview article

Targeting metabolism to regulate immune responses in autoimmunity and cancer

Patel, C. H., Leone, R. D., Horton, M. R. & Powell, J. D., Sep 1 2019, In : Nature Reviews Drug Discovery. 18, 9, p. 669-688 20 p.

Research output: Contribution to journalReview article

Targeting methionine auxotrophy in cancer: Discovery & exploration

Agrawal, V., Alpini, S. E. J., Stone, E. M., Frenkel, E. P. & Frankel, A. E., Jan 1 2012, In : Expert Opinion on Biological Therapy. 12, 1, p. 53-61 9 p.

Research output: Contribution to journalReview article

Targeting mTOR for cancer treatment

Rubio-Viqueira, B. & Hidalgo, M., Jun 1 2006, In : Current Opinion in Investigational Drugs. 7, 6, p. 501-512 12 p.

Research output: Contribution to journalReview article

Targeting mTOR for cancer treatment.

Rubio-Viqueira, B. & Hidalgo, M., 2006, In : Advances in experimental medicine and biology. 587, p. 309-327 19 p.

Research output: Contribution to journalReview article

Targeting Myeloid Cells in Combination Treatments for Glioma and Other Tumors

Ding, A. S., Routkevitch, D., Jackson, C. & Lim, M., 2019, In : Frontiers in immunology. 10, 1 p., 1715.

Research output: Contribution to journalReview article

Open Access

Targeting neoantigens to augment antitumour immunity

Yarchoan, M., Johnson, B. A., Lutz, E. R., Laheru, D. & Jaffee, E., Apr 1 2017, In : Nature Reviews Cancer. 17, 4, p. 209-222 14 p.

Research output: Contribution to journalReview article

Targeting Neural Hyperactivity as a Treatment to Stem Progression of Late-Onset Alzheimer’s Disease

Haberman, R. P., Branch, A. & Gallagher, M., Jul 1 2017, In : Neurotherapeutics. 14, 3, p. 662-676 15 p.

Research output: Contribution to journalReview article

Targeting normoxemia in acute respiratory distress syndrome may cause worse short-term outcomes because of oxygen toxicity

Aggarwal, N. R. & Brower, R. G., Nov 1 2014, In : Annals of the American Thoracic Society. 11, 9, p. 1449-1453 5 p.

Research output: Contribution to journalReview article

Targeting NRF2 signaling for cancer chemoprevention

Kwak, M. K. & Kensler, T. W., Apr 1 2010, In : Toxicology and Applied Pharmacology. 244, 1, p. 66-76 11 p.

Research output: Contribution to journalReview article

Targeting of membrane and secretory proteins to the apical domain in epithelial cells.

Hubbard, A. L., Dec 1991, In : Seminars in cell biology. 2, 6, p. 365-374 10 p.

Research output: Contribution to journalReview article

Targeting pediatric malignancies for T cell-mediated immune responses.

Mackall, C. L. & Helman, L. J., Nov 2000, In : Current oncology reports. 2, 6, p. 539-546 8 p.

Research output: Contribution to journalReview article

Targeting peripheral afferent nerve terminals for cough and dyspnea

Muroi, Y. & Undem, B. J., Jun 1 2011, In : Current Opinion in Pharmacology. 11, 3, p. 254-264 11 p.

Research output: Contribution to journalReview article

Targeting phosphatidylinositol 3-kinase-Akt through hepatocyte growth factor for cardioprotection

Madonna, R., Bolli, R., Rokosh, G. & De Caterina, R., Apr 1 2013, In : Journal of Cardiovascular Medicine. 14, 4, p. 249-253 5 p.

Research output: Contribution to journalReview article

Targeting phospholipid metabolism in cancer

Cheng, M., Bhujwalla, Z. M. & Glunde, K., 2016, In : Frontiers in Oncology. 6, DEC, 266.

Research output: Contribution to journalReview article

Targeting polyamine metabolism and function in cancer and other hyperproliferative diseases

Casero, R. A. & Marton, L. J., May 1 2007, In : Nature Reviews Drug Discovery. 6, 5, p. 373-390 18 p.

Research output: Contribution to journalReview article

Targeting polyamine metabolism for cancer therapy and prevention

Tracy, R. M. S., Woster, P. M. & Casero, R. A., 2016, In : Biochemical Journal. 473, 19, p. 2937-2953 17 p.

Research output: Contribution to journalReview article

Targeting prion-like protein spreading in neurodegenerative diseases

Zhang, Z., Nie, S. & Chen, L., 2018, In : Neural Regeneration Research. 13, 11, p. 1875-1878 4 p.

Research output: Contribution to journalReview article

Targeting RNA helicases in cancer: The translation trap

Heerma van Voss, M. R., van Diest, P. J. & Raman, V., Dec 1 2017, In : Biochimica et Biophysica Acta - Reviews on Cancer. 1868, 2, p. 510-520 11 p.

Research output: Contribution to journalReview article

Targeting Signaling Transduction Pathways in Bladder Cancer

Abbosh, P. H., McConkey, D. J. & Plimack, E. R., Dec 1 2015, In : Current oncology reports. 17, 12, 58.

Research output: Contribution to journalReview article

Targeting T cell metabolism to regulate T cell activation, differentiation and function in disease

Patel, C. H. & Powell, J., Jun 1 2017, In : Current Opinion in Immunology. 46, p. 82-88 7 p.

Research output: Contribution to journalReview article

Targeting teeth: Pediatric obesity and the dental office

Pont, S. J., Huizinga, M. M., Fields, W. T. & Beech, B. M., Jun 1 2008, In : Obesity Management. 4, 3, p. 104-110 7 p.

Research output: Contribution to journalReview article

Targeting TGFβ signaling in subchondral bone and articular cartilage homeostasis

Zhen, G. & Cao, X., May 2014, In : Trends in Pharmacological Sciences. 35, 5, p. 227-236 10 p.

Research output: Contribution to journalReview article

Targeting thapsigargin towards tumors

Doan, N. T. Q., Paulsen, E. S., Sehgal, P., Møller, J. V., Nissen, P., Denmeade, S. R., Isaacs, J. T., Dionne, C. A. & Christensen, S. B., May 2015, In : Steroids. 97, p. 2-7 6 p.

Research output: Contribution to journalReview article

Targeting the androgen receptor pathway in castration-resistant prostate cancer: Progresses and prospects

Ferraldeschi, R., Welti, J., Luo, J., Attard, G. & De Bono, J. S., May 19 2014, In : Oncogene. 34, 14, p. 1745-1757 13 p.

Research output: Contribution to journalReview article

Targeting the aryl hydrocarbon receptor/polyamine biosynthesis axis of evil for cancer therapy

Casero, R. A., Oct 1 2018, In : Journal of Clinical Investigation. 128, 10, p. 4254-4256 3 p.

Research output: Contribution to journalReview article

Targeting the cancer epigenome for therapy

Jones, P. A., Issa, J. P. J. & Baylin, S. B., Oct 1 2016, In : Nature Reviews Genetics. 17, 10, p. 630-641 12 p.

Research output: Contribution to journalReview article

Targeting the epidermal growth factor receptor in non-small-cell lung cancer: Who, which, when, and how?

Juergens, R. & Brahmer, J., Jul 1 2007, In : Current oncology reports. 9, 4, p. 255-264 10 p.

Research output: Contribution to journalReview article

Targeting the glutamatergic system for the treatment of HIV-associated neurocognitive disorders

Potter, M. C., Figuera-Losada, M., Rojas, C. & Slusher, B. S., Jun 1 2013, In : Journal of Neuroimmune Pharmacology. 8, 3, p. 594-607 14 p.

Research output: Contribution to journalReview article

Targeting the immune system in non-small-cell lung cancer: Bridging the gap between promising concept and therapeutic reality

Kelly, R., Gulley, J. & Giaccone, G., Jul 1 2010, In : Clinical lung cancer. 11, 4, p. 228-237 10 p.

Research output: Contribution to journalReview article

Targeting the immune system in the treatment of non-small-cell lung cancer

Rangachari, D. & Brahmer, J. R., Dec 1 2013, In : Current treatment options in oncology. 14, 4, p. 580-594 15 p.

Research output: Contribution to journalReview article

Targeting the Insulin Growth Factor Receptor 1

Arnaldez, F. I. & Helman, L. J., Jun 1 2012, In : Hematology/Oncology Clinics of North America. 26, 3, p. 527-542 16 p.

Research output: Contribution to journalReview article

Targeting the Latent Reservoir for HIV-1

Sengupta, S. & Siliciano, R. F., May 15 2018, In : Immunity. 48, 5, p. 872-895 24 p.

Research output: Contribution to journalReview article

Targeting the lipid metabolic pathways for the treatment of malaria

Mamoun, C. B., Prigge, S. T. & Vial, H., Feb 1 2010, In : Drug Development Research. 71, 1, p. 44-55 12 p.

Research output: Contribution to journalReview article