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• α-Catenin uses a novel mechanism to activate vinculin

  Peng, X., Maiers, J. L., Choudhury, D., Craig, S. W. & DeMali, K. A., Mar 2 2012, In: Journal of Biological Chemistry. 287, 10, p. 7728-7737 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Vinculin
  • Catenins
  • Talin
  • Adhesion
  • Adherens Junctions

• α-Catenin overrides Src-dependent activation of β-catenin oncogenic signaling

  Inge, L. J., Rajasekaran, S. A., Wolle, D., Barwe, S. P., Ryazantsev, S., Ewing, C. M., Isaacs, W. B. & Rajasekaran, A. K., 2008, In: Molecular cancer therapeutics. 7, 6, p. 1386-1397 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Catenins
  • Cadherins
  • Cell Adhesion
  • Cell Proliferation
  • Prostatic Neoplasms

• α-Catenin mediates initial E-cadherin-dependent cell- cell recognition and subsequent bond strengthening

  Bajpai, S., Correia, J., Feng, Y., Figueiredo, J., Sun, S. X., Longmore, G. D., Suriano, G. & Wirtz, D., Nov 25 2008, In: Proceedings of the National Academy of Sciences of the United States of America. 105, 47, p. 18331-18336 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Catenins
  • Cadherins
  • Multibond
  • Single Molecule Imaging
  • Germ-Line Mutation

• α-Catenin and IQGAP Regulate Myosin Localization to Control Epithelial Tube Morphogenesils in Dictyostelium

  Dickinson, D. J., Robinson, D. N., Nelson, W. J. & Weis, W. I., Sep 11 2012, In: Developmental Cell. 23, 3, p. 533-546 14 p.

  Research output: Contribution to journal › Article › peer-review

  • Myosin Type II
  • Dictyostelium
  • Catenins
  • Myosins
  • Epithelial Cells

• α-CaMKII-dependent plasticity in the cortex is required for permanent memory

  Frankland, P. W., O'Brien, C., Ohno, M., Kirkwood, A. & Silva, A. J., May 17 2001, In: Nature. 411, 6835, p. 309-313 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Calcium-Calmodulin-Dependent Protein Kinase Type 2
  • Memory
  • Memory Consolidation
  • Calcium-Calmodulin-Dependent Protein Kinases
  • Long-Term Potentiation

• α-Calcium-Calmodulin-Dependent Kinase II is Associated with Paired Helical Filaments of Alzheimer's Disease

  Xiao, J., Perry, G., Troncoso, J. & Monteiro, M. J., 1996, In: Journal of neuropathology and experimental neurology. 55, 9, p. 954-963 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Calcium-Calmodulin-Dependent Protein Kinases
  • Alzheimer Disease
  • Phosphotransferases
  • Calcium
  • Neurofibrillary Tangles

• αB-Crystallin negative astrocytic inclusions

  Barnett, B. P., Bressler, J., Chen, T., Hutchins, G. M., Crain, B. J. & Kaufmann, W. E., Apr 2011, In: Brain and Development. 33, 4, p. 349-352 4 p.

  Research output: Contribution to journal › Article › peer-review

  • Crystallins
  • Cerebral Cortex
  • Perisylvian syndrome
  • Astrocytes
  • acid fuchsin

• αB-Crystallin Maintains Skeletal Muscle Myosin Enzymatic Activity and Prevents its Aggregation under Heat-shock Stress

  Melkani, G. C., Cammarato, A. & Bernstein, S. I., May 5 2006, In: Journal of molecular biology. 358, 3, p. 635-645 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Skeletal Muscle Myosins
  • Crystallins
  • Heat-Shock Response
  • Myosins
  • Hot Temperature

• α- and β-adrenergic mechanisms in the control of vascular capacitance by the carotid sinus baroreflex system

  Shigemi, K., Brunner, M. J. & Shoukas, A. A., 1994, In: American Journal of Physiology - Heart and Circulatory Physiology. 267, 1 36-1, p. H201-H210

  Research output: Contribution to journal › Article › peer-review

  • Vascular Capacitance
  • Carotid Sinus
  • capacitance
  • Baroreflex
  • sinuses

• α‐ADRENOCEPTORS CAN MEDIATE CHRONOTROPIC RESPONSES IN THE RAT HEART

  FLAVAHAN, N. A. & McGRATH, J. C., Jul 1981, In: British Journal of Pharmacology. 73, 3, p. 586-588 3 p.

  Research output: Contribution to journal › Article › peer-review

  • Prazosin
  • Propranolol
  • amidephrine
  • Adrenergic Receptors
  • (2-(2',6'-dimethoxy)phenoxyethylamino)methylbenzo-1,4-dioxane

• α-Adrenoceptor mechanisms of thermoregulation during cold challenge in humans

  Frank, S. M., El-Gamal, N., Raja, S. N. & Wu, P. K., 1996, In: Clinical Science. 91, 5, p. 627-631 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Body Temperature Regulation
  • Vasoconstriction
  • Adrenergic Receptors
  • Cold Temperature
  • Shivering

• α-Adrenergic regulation of phosphoinositide metabolism and protein kinase C in isolated cardiac myocytes

  Kaku, T., Lakatta, E. & Filburn, C., Apr 29 1991, In: American Journal of Physiology - Cell Physiology. 260, 3 29-3, p. C635-C642

  Research output: Contribution to journal › Article › peer-review

  • 1-Phosphatidylinositol 4-Kinase
  • Adrenergic Agents
  • Protein Kinase C
  • Cardiac Myocytes
  • Norepinephrine

• α-Adrenergic modification of the Ca²⁺ transient and contraction in single rat cardiomyocytes

  O'Rourke, B., Reibel, D. K. & Thomas, A. P., Aug 1992, In: Journal of Molecular and Cellular Cardiology. 24, 8, p. 809-820 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Adrenergic Agents
  • Adrenergic Receptors
  • Cardiac Myocytes
  • Fura-2

• α-Adrenergic mechanisms of thermoregulation in humans

  Frank, S. M., Raja, S. N., Wu, P. K. & El-Gamal, N., 1997, In: Annals of the New York Academy of Sciences. 813, p. 101-110 10 p.

  Research output: Contribution to journal › Article › peer-review

• α-actinin and filamin cooperatively enhance the stiffness of actin filament networks

  Esue, O., Tseng, Y. & Wirtz, D., Feb 9 2009, In: PloS one. 4, 2, e4411.

  Research output: Contribution to journal › Article › peer-review

  • filamin
  • Filamins
  • Actinin
  • microfilaments
  • Actin Cytoskeleton

• α9: An acetylcholine receptor with novel pharmacological properties expressed in rat cochlear hair cells

  Elgoyhen, A. B., Johnson, D. S., Boulter, J., Vetter, D. E. & Heinemann, S., Nov 18 1994, In: Cell. 79, 4, p. 705-715 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Auditory Hair Cells
  • Rats
  • Cholinergic Receptors
  • Cells
  • Cholinergic Agents

• α8 integrin in glomerular mesangial cells and in experimental glomerulonephritis

  Hartner, A., Schöckliviann, H., Pröls, F., Müller, U. & Bernd Sterzel, R., 1999, In: Kidney international. 56, 4, p. 1468-1480 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Mesangial Cells
  • Glomerulonephritis
  • Integrins
  • Kidney
  • Nephritis

• α7 nicotinic acetylcholine receptor mRNA expression and binding in postmortem human brain are associated with genetic variation in neuregulin

  Mathew, S. V., Law, A. J., Lipska, B. K., Dávila-García, M. I., Zamora, E. D., Mitkus, S. N., Vakkalanka, R., Straub, R. E., Weinberger, D. R., Kleinman, J. E. & Hyde, T. M., Dec 1 2007, In: Human molecular genetics. 16, 23, p. 2921-2932 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Neuregulins
  • Neuregulin-1
  • Nicotinic Receptors
  • Genetic Variation
  • Prefrontal Cortex

• α5-GABAA receptors negatively regulate MYC-amplified medulloblastoma growth

  Sengupta, S., Weeraratne, S. D., Sun, H., Phallen, J., Rallapalli, S. K., Teider, N., Kosaras, B., Amani, V., Pierre-Francois, J., Tang, Y., Nguyen, B., Yu, F., Schubert, S., Balansay, B., Mathios, D., Lechpammer, M., Archer, T. C., Tran, P., Reimer, R. J., Cook, J. M. & 4 others, Lim, M., Jensen, F. E., Pomeroy, S. L. & Cho, Y. J., Apr 2014, In: Acta neuropathologica. 127, 4, p. 593-603 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Medulloblastoma
  • GABA-A Receptors
  • Growth
  • Brain Neoplasms
  • Cell Survival

• α-5/α-3 nicotinic receptor subunit alleles increase risk for heavy smoking

  Berrettini, W., Yuan, X., Tozzi, F., Song, K., Francks, C., Chilcoat, H., Waterworth, D., Muglia, P. & Mooser, V., Apr 2008, In: Molecular Psychiatry. 13, 4, p. 368-373 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Tobacco Use Disorder
  • Nicotinic Receptors
  • Tobacco Products
  • Haplotypes
  • Alleles

• α4β1 integrin regulates lamellipodia protrusion via a focal complex/focal adhesion-independent mechanism

  Pinco, K. A., He, W. & Yang, J. T., Sep 2002, In: Molecular Biology of the Cell. 13, 9, p. 3203-3217 15 p.

  Research output: Contribution to journal › Article › peer-review

  • Pseudopodia
  • Focal Adhesions
  • Integrins
  • Paxillin
  • Green Fluorescent Proteins

• α₄β₁-Integrin regulates directionally persistent cell migration in response to shear flow stimulation

  Dikeman, D. A., Rivera Rosado, L. A., Horn, T. A., Alves, C. S., Konstantopoulos, K. & Yang, J. T., Jul 2008, In: American Journal of Physiology - Cell Physiology. 295, 1, p. C151-C159

  Research output: Contribution to journal › Article › peer-review

  • Integrins
  • Cell Movement
  • Paxillin
  • Phosphorylation
  • Mutation

• α4 integrins regulate the proliferation/differentiation balance of multilineage hematopoietic progenitors in vivo

  Arroyo, A. G., Yang, J. T., Rayburn, H. & Hynes, R. O., Nov 1999, In: Immunity. 11, 5, p. 555-566 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Integrins
  • B-Lymphoid Precursor Cells
  • Spleen
  • Bone Marrow
  • Hematopoiesis

• α4 integrin is expressed in a subset of cranial neural crest cells and in epicardial progenitor cells during early mouse development

  Pinco, K. A., Liu, S. & Yang, J. T., 2001, In: Mechanisms of Development. 100, 1, p. 99-103 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Rhombencephalon
  • Neural Crest
  • Prosencephalon
  • Mesencephalon
  • Integrins

• α3β1 integrin promotes keratinocyte cell survival through activation of a MEK/ERK signaling pathway

  Manohar, A., Shome, S. G., Lamar, J., Stirling, L., Iyer, V., Pumiglia, K. & DiPersio, C. M., Aug 15 2004, In: Journal of cell science. 117, 18, p. 4043-4054 12 p.

  Research output: Contribution to journal › Article › peer-review

  • kalinin
  • Mitogen-Activated Protein Kinase Kinases
  • Extracellular Signal-Regulated MAP Kinases
  • Keratinocytes
  • Integrins

• α₂-Macroglobulin is a binding protein for basic fibroblast growth factor

  Dennis, P. A., Saksela, O., Harpel, P. & Rifkin, D. B., 1989, In: Journal of Biological Chemistry. 264, 13, p. 7210-7216 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Macroglobulins
  • Fibroblast Growth Factor 2
  • Carrier Proteins
  • Molecular mass
  • Autoradiography

• α₁-Antitrypsin deficiency in twins and parents-of-twins

  Lieberman, J., Borhani, N. O. & Feinleib, M., 1979, In: Clinical Genetics. 15, 1, p. 29-36 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Trypsin
  • Fertility
  • Peptide Hydrolases
  • Gametogenesis
  • Fertilization

• α₁-Antichymotrypsin is present together with the β-protein in monkey brain amyloid deposits

  Abraham, C. R., Selkoe, D. J., Potter, H., Price, D. L. & Cork, L. C., 1989, In: Neuroscience. 32, 3, p. 715-720 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Amyloid Plaques
  • Amyloid
  • Haplorhini
  • Brain
  • Proteins

• α₁ and α₂-adrenoceptor-mediated pressor and chronotropic effects in the rat and rabbit

  McGrath, J. C., Flavahan, N. A. & McKean, C. E., Jan 1 1982, In: Journal of cardiovascular pharmacology. 4, p. S101-S107

  Research output: Contribution to journal › Article › peer-review

  • Adrenergic Receptors
  • Yohimbine
  • Rabbits
  • Prazosin
  • Xylazine

• α₁- and α₂-adrenoceptor agonism is dependent on respiratory acid-base balance

  Flavahan, N. A. & McGrath, J. C., Jan 1 1981, In: British Journal of Pharmacology. 74, 4, p. 804P

  Research output: Contribution to journal › Article › peer-review

• α₁-Adrenoceptor subclassification in vascular smooth muscle

  Flavahan, N. A. & Vanhoutte, P. M., 1986, In: Trends in Pharmacological Sciences. 7, C, p. 347-349 3 p.

  Research output: Contribution to journal › Article › peer-review

  • Yohimbine
  • Prazosin
  • Blood vessels
  • Vascular Smooth Muscle
  • Adrenergic Receptors

• α₁-Adrenoceptor antagonists terazosin and doxazosin induce prostate apoptosis without affecting cell proliferation in patients with benign prostatic hyperplasia

  Chon, J. K., Borkowski, A., Partin, A. W., Isaacs, J. T., Jacobs, S. C. & Kyprianou, N., Jun 1999, In: Journal of Urology. 161, 6, p. 2002-2008 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Terazosin
  • Doxazosin
  • Prostatic Hyperplasia
  • Adrenergic Receptors
  • Prostate

• α ₁‐ADRENOCEPTOR ACTIVATION CAN INCREASE HEART RATE DIRECTLY OR DECREASE IT INDIRECTLY THROUGH PARASYMPATHETIC ACTIVATION

  FLAVAHAN, N. A. & McGRATH, J. C., Oct 1982, In: British Journal of Pharmacology. 77, 2, p. 319-328 10 p.

  Research output: Contribution to journal › Article › peer-review

  • amidephrine
  • Phenylephrine
  • Adrenergic Receptors
  • Xylazine
  • Heart Rate

• α₁-Adrenergic blockade does not alter control of skin blood flow during exercise

  Kenney, W. L., Tankersley, C. G., Newswanger, D. L. & Puhl, S. M., Jan 1 1991, In: American Journal of Physiology - Heart and Circulatory Physiology. 260, 3 29-3, p. H855-H861

  Research output: Contribution to journal › Article › peer-review

  • Adrenergic Agents
  • Prazosin
  • Exercise
  • Forearm
  • Skin

• α_1a-adrenergic receptor induces activation of extracellular signal-regulated kinase 1/2 through endocytic pathway

  Liu, F., He, K., Yang, X., Xu, N., Liang, Z., Xu, M., Zhao, X., Han, Q. & Zhang, Y., 2011, In: PloS one. 6, 6, e21520.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Mitogen-Activated Protein Kinase 3
  • adrenergic receptors
  • Mitogen-Activated Protein Kinase 1
  • mitogen-activated protein kinase
  • Adrenergic Receptors

• α10: A determinant of nicotinic cholinergic receptor function in mammalian vestibular and cochlear mechanosensory hair cells

  Elgoyhen, A. B., Vetter, D. E., Katz, E., Rothlin, C. V., Heinemann, S. F. & Boulter, J., Mar 13 2001, In: Proceedings of the National Academy of Sciences of the United States of America. 98, 6, p. 3501-3506 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Auditory Hair Cells
  • Nicotinic Receptors
  • Cholinergic Receptors
  • Complementary RNA
  • Genes

• α⁺-thalassemia protects African children from severe malaria

  Mockenhaupt, F. P., Ehrhardt, S., Gellert, S., Otchwemah, R. N., Dietz, E., Anemana, S. D. & Bienzle, U., Oct 1 2004, In: Blood. 104, 7, p. 2003-2006 4 p.

  Research output: Contribution to journal › Article › peer-review

  • Thalassemia
  • Malaria
  • Child
  • Genetic Selection
  • Odds Ratio

• α(1L)-Adrenoceptors in canine pulmonary artery

  Flavahan, N. A., Hales, M. A., Aleskowitch, T. D., Gaine, S. P. & Vanhoutte, P. M., Aug 1 1998, In: Journal of cardiovascular pharmacology. 32, 2, p. 308-316 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Prazosin
  • Adrenergic Receptors
  • Pulmonary Artery
  • Canidae
  • Phenylephrine

• α,β-unsaturated carbonyl system of chalcone-based derivatives is responsible for broad inhibition of proteasomal activity and preferential killing of human papilloma virus (HPV) positive cervical cancer cells

  Bazzaro, M., Anchoori, R. K., Mudiam, M. K. R., Issaenko, O., Kumar, S., Karanam, B., Lin, Z., Isaksson Vogel, R., Gavioli, R., Destro, F., Ferretti, V., Roden, R. B. S. & Khan, S. R., Jan 27 2011, In: Journal of medicinal chemistry. 54, 2, p. 449-456 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Papillomaviridae
  • Proteasome Inhibitors
  • Uterine Cervical Neoplasms
  • hydroxythreonine
  • Piperidones

• Δ-PCR, a simple method to detect translocations and insertion/deletion mutations

  Lin, M. T., Tseng, L. H., Rich, R. G., Hafez, M. J., Harada, S., Murphy, K. M., Eshleman, J. R. & Gocke, C. D., Jan 2011, In: Journal of Molecular Diagnostics. 13, 1, p. 85-92 8 p.

  Research output: Contribution to journal › Article › peer-review

  • INDEL Mutation
  • Follicular Lymphoma
  • Polymerase Chain Reaction
  • Mutation
  • Capillary Electrophoresis

• ΔNp63α up-regulates the Hsp70 gene in human cancer

  Wu, G., Osada, M., Guo, Z., Fomenkov, A., Begum, S., Zhao, M., Upadhyay, S., Xing, M., Wu, F., Moon, C., Westra, W. H., Koch, W. M., Mantovani, R., Califano, J. A., Ratovitski, E., Sidransky, D. & Trink, B., Feb 1 2005, In: Cancer Research. 65, 3, p. 758-766 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Head and Neck Neoplasms
  • CCAAT-Binding Factor
  • Protein Isoforms
  • Up-Regulation
  • Heat-Shock Proteins

• ΔNp63α overexpression induces downregulation of Sirt1 and an accelerated aging phenotype in the mouse

  Sommer, M., Poliak, N., Upadhyay, S., Ratovitski, E., Nelkin, B. D., Donehower, L. A. & Sidransky, D., Sep 1 2006, In: Cell Cycle. 5, 17, p. 2005-2011 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Sirtuin 1
  • Skin
  • Aging of materials
  • Down-Regulation
  • Phenotype

• ΔNp63α levels correlate with clinical tumor response to cisplatin

  Zangen, R., Ratovitski, E. & Sidransky, D., Oct 2005, In: Cell Cycle. 4, 10, p. 1313-1315 3 p.

  Research output: Contribution to journal › Short survey › peer-review

  Open Access

  • Tumors
  • Cisplatin
  • DNA Damage
  • Phosphorylation
  • Head and Neck Neoplasms

• ΔNp63α confers tumor cell resistance to cisplatin through the AKT1 transcriptional regulation

  Sen, T., Sen, N., Brait, M., Begum, S., Chatterjee, A., Hoque, M. O., Ratovitski, E. & Sidransky, D., Feb 1 2011, In: Cancer Research. 71, 3, p. 1167-1176 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Cisplatin
  • Head and Neck Neoplasms
  • Neoplasms
  • Cell Proliferation
  • Ovarian Epithelial Carcinoma

• ΔNp63α and TAp63α regulate transcription of genes with distinct biological functions in cancer and development

  Wu, G., Nomoto, S., Hoque, M. O., Dracheva, T., Osada, M., Lee, C. C. R., Dong, S. M., Guo, Z., Benoit, N., Cohen, Y., Rechthand, P., Califano, J., Moon, C. S., Ratovitski, E., Jen, J., Sidransky, D. & Trink, B., May 15 2003, In: Cancer Research. 63, 10, p. 2351-2357 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Genes
  • Neoplasms
  • Oligonucleotide Array Sequence Analysis
  • p53 Genes
  • Neoplasm Genes

• Δnp63α/IRF6 interplay activates NOS2 transcription and induces autophagy upon tobacco exposure

  Ratovitski, E. A., Feb 15 2011, In: Archives of Biochemistry and Biophysics. 506, 2, p. 208-215 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Tobacco
  • Head and Neck Neoplasms
  • Autophagy
  • Cells
  • Smoke

• ΔNp63 versatilely regulates a broad NF-κB gene program and promotes squamous epithelial proliferation, migration, and inflammation

  Yang, X., Lu, H., Yan, B., Romano, R. A., Bian, Y., Friedman, J., Duggal, P., Allen, C., Chuang, R., Ehsanian, R., Si, H., Sinha, S., Van Waes, C. & Chen, Z., May 15 2011, In: Cancer Research. 71, 10, p. 3688-3700 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Squamous Cell Carcinoma of Head and Neck
  • Inflammation
  • Genes
  • Interleukin-8
  • Hyperplasia

• ΔNp63 induces β-catenin nuclear accumulation and signaling

  Patturajan, M., Nomoto, S., Sommer, M., Fomenkov, A., Hibi, K., Zangen, R., Poliak, N., Califano, J., Trink, B., Ratovitski, E. & Sidransky, D., May 2002, In: Cancer cell. 1, 4, p. 369-379 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Catenins
  • Glycogen Synthase Kinase 3
  • Protein Phosphatase 2
  • Squamous Cell Carcinoma
  • Phosphorylation

• Δnp63 (p40) expression in prostatic adenocarcinoma with diffuse p63 positivity

  Uchida, K., Ross, H., Lotan, T., Pignon, J. C., Signoretti, S., Epstein, J. I. & Illei, P. B., Mar 1 2015, In: Human pathology. 46, 3, p. 384-389 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Adenocarcinoma
  • Keratins
  • Molecular Weight
  • Neoplasms
  • Protein Isoforms

• Δ⁵-3-Ketosteroid Isomerase

  Talalay, P. & Benson, A. M., Jan 1 1972, In: Enzymes. 6, C, p. 591-618 28 p.

  Research output: Contribution to journal › Article › peer-review

  • steroid delta-isomerase
  • Ketosteroids
  • Wavelength
  • Hydroxysteroids
  • Absorption spectra