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  • James Segars
2016

Zika Virus: A Race to Prevent a Reproductive Crisis

Sheffield, J. & Segars, J., Sep 1 2016, In : Seminars in reproductive medicine. 34, 5, p. 259-260 2 p.

Research output: Contribution to journalArticle

2018

A miRNA181a/NFAT5 axis links impaired T cell tolerance induction with autoimmune type 1 diabetes

Serr, I., Scherm, M. G., Zahm, A. M., Schug, J., Flynn, V. K., Hippich, M., Kälin, S., Becker, M., Achenbach, P., Nikolaev, A., Gerlach, K., Liebsch, N., Loretz, B., Lehr, C. M., Kirchner, B., Spornraft, M., Haase, B., Segars, J., Küper, C., Palmisano, R. & 7 others, Waisman, A., Willis, R. A., Kim, W. U., Weigmann, B., Kaestner, K. H., Ziegler, A. G. & Daniel, C., Jan 3 2018, In : Science Translational Medicine. 10, 422, eaag1782.

Research output: Contribution to journalArticle

Assisted Reproductive Technologies and the Developmental Origins of Health and Disease

Segars, J., Jan 1 2018, In : Seminars in reproductive medicine. 36, 3-4, 1 p.

Research output: Contribution to journalEditorial

2017

Treatment modalities for fibroids, indications, risks, and benefits

Garg, D. & Segars, J., Oct 13 2017, Uterine Fibroids: A Clinical Casebook. Springer International Publishing, p. 87-106 20 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Uterine Leiomyoma: New Perspectives on an Old Disease

Segars, J. & Al-Hendy, A., Nov 1 2017, In : Seminars in Reproductive Medicine. 35, 6, p. 471-472 2 p.

Research output: Contribution to journalEditorial

Zika virus and assisted reproduction

Cordeiro, C. N., Bano, R., Cross, C. & Segars, J., Jun 1 2017, In : Current Opinion in Obstetrics and Gynecology. 29, 3, p. 175-179 5 p.

Research output: Contribution to journalReview article

2018

Jacques Cohen, PhD

Segars, J., Jan 1 2018, In : Seminars in reproductive medicine. 36, 5, p. 249-250 2 p.

Research output: Contribution to journalEditorial

Ulipristal acetate for treatment of symptomatic uterine leiomyomas: A randomized controlled trial

Simon, J. A., Catherino, W., Segars, J., Blakesley, R. E., Chan, A., Sniukiene, V. & Al-Hendy, A., Jan 1 2018, In : Obstetrics and Gynecology. 131, 3, p. 431-439 9 p.

Research output: Contribution to journalArticle

2017

Cancer-associated mutations in endometriosis without cancer

Anglesio, M. S., Papadopoulos, N., Ayhan, A., Nazeran, T. M., Noë, M., Horlings, H. M., Lum, A., Jones, S., Senz, J., Seckin, T., Ho, J., Wu, R. C., Lac, V., Ogawa, H., Tessier-Cloutier, B., Alhassan, R., Wang, A., Wang, Y., Cohen, J. D., Wong, F. & 20 others, Hasanovic, A., Orr, N., Zhang, M., Popoli, M., McMahon, W., Wood, L. D., Mattox, A., Allaire, C., Segars, J., Williams, C., Tomasetti, C., Boyd, N., Kinzler, K. W., Gilks, C. B., Diaz, L., Wang, T. L., Vogelstein, B., Yong, P. J., Huntsman, D. G. & Shih, I. M., May 11 2017, In : New England Journal of Medicine. 376, 19, p. 1835-1848 14 p.

Research output: Contribution to journalArticle

2018

Biomechanics and mechanical signaling in the ovary: a systematic review

Shah, J. S., Sabouni, R., Cayton Vaught, K. C., Owen, C. M., Albertini, D. F. & Segars, J., Apr 24 2018, (Accepted/In press) In : Journal of Assisted Reproduction and Genetics. p. 1-14 14 p.

Research output: Contribution to journalArticle

2017

Recent advances in the field of ovarian tissue cryopreservation and opportunities for research

Ladanyi, C., Mor, A., Christianson, M. S., Dhillon, N. & Segars, J., Apr 1 2017, (Accepted/In press) In : Journal of Assisted Reproduction and Genetics. p. 1-14 14 p.

Research output: Contribution to journalArticle

Mechanical Signaling and Extracellular Matrix in Uterine Fibroids

Rafique, S., Segars, J. H. & Leppert, P. C., Nov 1 2017, In : Seminars in reproductive medicine. 35, 6, p. 487-493 7 p.

Research output: Contribution to journalArticle

2018

Female Offspring from Chronic Hyperandrogenemic Dams Exhibit Delayed Puberty and Impaired Ovarian Reserve

Wang, Z., Shen, M., Xue, P., Divall, S., Segars, J. & Wu, S., Feb 2018, In : Endocrinology. 159, 2, p. 1242-1252 11 p.

Research output: Contribution to journalArticle

2016

In Vitro Activation: A Possible New Frontier for Treatment of Primary Ovarian Insufficiency

Cordeiro, C. N., Christianson, M. S., Selter, J. H. & Segars, J. H., Apr 1 2016, In : Reproductive Sciences. 23, 4, p. 429-438 10 p.

Research output: Contribution to journalArticle

2020

Epithelial Cells in Endometriosis and Adenomyosis Upregulate STING Expression

Qu, H., Li, L., Wang, T. L., Seckin, T., Segars, J. & Shih, I. M., Jun 1 2020, In : Reproductive Sciences. 27, 6, p. 1276-1284 9 p.

Research output: Contribution to journalArticle

2017

Maternal T Regulatory Cell Depletion Impairs Embryo Implantation Which Can Be Corrected with Adoptive T Regulatory Cell Transfer

Heitmann, R. J., Weitzel, R. P., Feng, Y., Segars, J., Tisdale, J. F. & Wolff, E. F., Jul 1 2017, In : Reproductive Sciences. 24, 7, p. 1014-1024 11 p.

Research output: Contribution to journalArticle

2016

Pravastatin to prevent recurrent fetal death in massive perivillous fibrin deposition of the placenta (MPFD)

Chaiworapongsa, T., Romero, R., Korzeniewski, S. J., Chaemsaithong, P., Hernandez-Andrade, E., Segars, J. H., Decherney, A. H., McCoy, M. C., Kim, C. J., Yeo, L. & Hassan, S. S., Mar 18 2016, In : Journal of Maternal-Fetal and Neonatal Medicine. 29, 6, p. 855-862 8 p.

Research output: Contribution to journalArticle

An evidence-based approach to the medical management of fibroids: A systematic review

Bartels, C. B., Cayton, K. C., Chuong, F. S., Holthouser, K., Mehr, S. A., Abraham, T. & Segars, J. H., Jan 1 2016, In : Clinical obstetrics and gynecology. 59, 1, p. 30-52 23 p.

Research output: Contribution to journalReview article

2017

Hysteroscopic polypectomy prior to infertility treatment: A cost analysis and systematic review

Mouhayar, Y., Yin, O., Mumford, S. L. & Segars, J., Jun 1 2017, In : European Journal of Obstetrics Gynecology and Reproductive Biology. 213, p. 107-115 9 p.

Research output: Contribution to journalReview article

2018

Is thromboprophylaxis cost effective in ovarian hyperstimulation syndrome: A systematic review and cost analysis

Wormer, K. C., Jangda, A. A., El Sayed, F. A., Stewart, K. I., Mumford, S. L. & Segars, J., May 1 2018, In : European Journal of Obstetrics Gynecology and Reproductive Biology. 224, p. 117-124 8 p.

Research output: Contribution to journalReview article

2016

Practice patterns, satisfaction, and demographics of reproductive endocrinologists: Results of the 2014 Society for Reproductive Endocrinology and Infertility Workforce Survey

Barnhart, K. T., Nakajima, S. T., Puscheck, E., Price, T. M., Baker, V. L. & Segars, J., May 1 2016, In : Fertility and sterility. 105, 5, p. 1281-1286 6 p.

Research output: Contribution to journalArticle

2018

Unleashing the potential of stem cells to help poor responders

Christianson, M. S. & Segars, J., Aug 1 2018, In : Fertility and Sterility. 110, 3, p. 410-411 2 p.

Research output: Contribution to journalEditorial

2017

Dietary phytochemicals for possible preventive and therapeutic option of uterine fibroids: Signaling pathways as target

Islam, M. S., Segars, J., Castellucci, M. & Ciarmela, P., Feb 1 2017, In : Pharmacological Reports. 69, 1, p. 57-70 14 p.

Research output: Contribution to journalReview article

Progesterone-Mediated Non-Classical Signaling

Garg, D., Ng, S. S. M., Baig, K. M., Driggers, P. & Segars, J., 2017, (Accepted/In press) In : Trends in Endocrinology and Metabolism.

Research output: Contribution to journalArticle

2016
2017

Reproductive ovarian testing and the alphabet soup of diagnoses: DOR, POI, POF, POR, and FOR

Pastore, L. M., Christianson, M. S., Stelling, J., Kearns, W. G. & Segars, J., Oct 2 2017, (Accepted/In press) In : Journal of Assisted Reproduction and Genetics. p. 1-7 7 p.

Research output: Contribution to journalArticle

2018

Ulipristal acetate for treatment of symptomatic uterine leiomyomas: A randomized controlled trial

Simon, J. A., Catherino, W., Segars, J., Blakesley, R. E., Chan, A., Sniukiene, V. & Al-Hendy, A., Jun 1 2018, In : Obstetrical and Gynecological Survey. 73, 6, p. 350-352 3 p.

Research output: Contribution to journalComment/debate

2020

Frozen-thawed embryo transfer: the potential importance of the corpus luteum in preventing obstetrical complications

Singh, B., Reschke, L., Segars, J. & Baker, V. L., Feb 2020, In : Fertility and sterility. 113, 2, p. 252-257 6 p.

Research output: Contribution to journalReview article

2018

Evaluation, validation and refinement of noninvasive diagnostic biomarkers for endometriosis (ENDOmarker): A protocol to phenotype bio-specimens for discovery and validation

for the NICHD Cooperative Reproductive Medicine Network, May 1 2018, In : Contemporary Clinical Trials. 68, p. 1-6 6 p.

Research output: Contribution to journalArticle

2017

Preconception assisted reproductive technology counseling in the age of Zika

Cross, C. & Segars, J., 2017, (Accepted/In press) In : Fertility and Sterility.

Research output: Contribution to journalArticle

2018

When is recombinant luteinizing hormone supplementation beneficial during ovarian stimulation?

Maher, J. Y. & Segars, J., Apr 1 2018, In : Fertility and Sterility. 109, 4, p. 611-612 2 p.

Research output: Contribution to journalEditorial

2017

Cancer Implications for Patients with Endometriosis

Wilbur, M. A., Shih, I. M., Segars, J. & Nickles Fader, A. N., Jan 1 2017, In : Seminars in Reproductive Medicine. 35, 1, p. 110-116 7 p.

Research output: Contribution to journalArticle

2018

Mice deficient in AKAP13 (BRX) develop compulsive-like behavior and increased body weight

Maravet Baig, K., Su, S. C., Mumford, S. L., Giuliani, E., Ng, S. S. M., Armstrong, C., Keil, M. F., Vaught, K. C., Olsen, N., Pettiford, E., Burd, I. & Segars, J., Jun 1 2018, In : Brain Research Bulletin. 140, p. 72-79 8 p.

Research output: Contribution to journalArticle

2017

Molecular targets of dietary phytochemicals for possible prevention and therapy of uterine fibroids: Focus on fibrosis

Islam, M. S., Akhtar, M. M., Segars, J., Castellucci, M. & Ciarmela, P., Nov 22 2017, In : Critical Reviews in Food Science and Nutrition. 57, 17, p. 3583-3600 18 p.

Research output: Contribution to journalArticle

2018

Alicia YChristy, MD, MHSCR, FACOG and Richard Burney, MD, MSc

Segars, J., Nov 19 2018, In : Seminars in reproductive medicine. 36, 6, 1 p.

Research output: Contribution to journalEditorial

2017

Pravastatin for the prevention of adverse pregnancy outcome: preeclampsia and more?

Chaiworapongsa, T., Romero, R., Korzeniewski, S. J., Chaemsaithong, P., Hernandez-Andrade, E., Segars, J. H., DeCherney, A. H., McCoy, M. C., Kim, C. J., Yeo, L. & Hassan, S. S., Jan 2 2017, In : Journal of Maternal-Fetal and Neonatal Medicine. 30, 1, 1 p.

Research output: Contribution to journalLetter

2016

Keeping the Zika Virus Out of the Assisted Reproductive Technology Laboratory

Washington, C. I., Haque, S., Segars, J. H., Bracero, N., Rodriguez, F., Ball, G. D. & Davis, O. K., Sep 1 2016, In : Seminars in reproductive medicine. 34, 5, p. 293-298 6 p.

Research output: Contribution to journalArticle

Erratum: An evidence-based approach to the medical management of fibroids: A systematic review (Clinical Obstetrics and Gynecology (2016) 59 (30-52))

Bartels, C. B., Cayton, K. C., Chuong, F. S., Holthouser, K., Arian, S. E., Abraham, T. & Segars, J. H., 2016, In : Clinical Obstetrics and Gynecology. 59, 2, p. 447 1 p.

Research output: Contribution to journalArticle

2020

Prior and novel coronaviruses, Coronavirus Disease 2019 (COVID-19), and human reproduction: what is known?

American Society for Reproductive Medicine Coronavirus/COVID-19 Task Force, Jun 2020, In : Fertility and sterility. 113, 6, p. 1140-1149 10 p.

Research output: Contribution to journalArticle

Open Access
2016

Zika Virus in Semen: What We Know and What We Need to Know

Gornet, M. E., Bracero, N. J. & Segars, J., Sep 1 2016, In : Seminars in Reproductive Medicine. 34, 5, p. 285-292 8 p.

Research output: Contribution to journalArticle

2017

The Effect of Uterine Fibroids on Infertility: A Systematic Review

Whynott, R. M., Vaught, K. C. C. & Segars, J., Nov 1 2017, In : Seminars in Reproductive Medicine. 35, 6, p. 523-532 10 p.

Research output: Contribution to journalReview article

2018

Simvastatin, at clinically relevant concentrations, affects human uterine leiomyoma growth and extracellular matrix production

Malik, M., Britten, J., Borahay, M., Segars, J. & Catherino, W. H., Dec 1 2018, In : Fertility and Sterility. 110, 7, p. 1398-1407.e1

Research output: Contribution to journalArticle

2016

CRTC2 is a coactivator of GR and couples GR and CREB in the regulation of hepatic gluconeogenesis

Hill, M. J., Suzuki, S., Segars, J. H. & Kino, T., Jan 2016, In : Molecular Endocrinology. 30, 1, p. 104-117 14 p.

Research output: Contribution to journalArticle

2020

Simvastatin ameliorates altered mechanotransduction in uterine leiomyoma cells

Afrin, S., Islam, M. S., Patzkowsky, K., Malik, M., Catherino, W. H., Segars, J. H. & Borahay, M., 2020, (Accepted/In press) In : American journal of obstetrics and gynecology.

Research output: Contribution to journalArticle

Navigating the body of literature assessing BRCA1/2 mutations and markers of ovarian function: a systematic review and meta-analysis

Cordeiro Mitchell, C. N., McGuinness, B., Fine, E., Kearns, W. G., Christianson, M. S., Segars, J. & Pastore, L. M., May 1 2020, In : Journal of Assisted Reproduction and Genetics. 37, 5, p. 1037-1055 19 p.

Research output: Contribution to journalReview article

2017

P2X7 receptor blockade prevents preterm birth and perinatal brain injury in a mouse model of intrauterine inflammation

Tsimis, M. E., Lei, J., Rosenzweig, J. M., Arif, H., Shabi, Y., Alshehri, W., Talbot, C. C., Baig-Ward, K. M., Segars, J., Graham, E. M. & Burd, I., Aug 1 2017, In : Biology of Reproduction. 97, 2, p. 230-239 10 p.

Research output: Contribution to journalArticle

2016

Vaginal Pessary for Uterine Repositioning during High-Intensity Focused Ultrasound Ablation of Uterine Leiomyomas

Klepac Pulanic, T., Venkatesan, A. M., Segars, J., Sokka, S., Wood, B. J. & Stratton, P., May 1 2016, In : Gynecologic and Obstetric Investigation. 81, 3, p. 285-288 4 p.

Research output: Contribution to journalReview article

2020

Selective Progesterone Receptor Modulators-Mechanisms and Therapeutic Utility

Islam, M. S., Afrin, S., Jones, S. I. & Segars, J., Oct 1 2020, In : Endocrine Reviews. 41, 5

Research output: Contribution to journalArticle

Open Access

Hypothalamic-Pituitary-Adrenal Axis Responses in Women with Endometriosis-Related Chronic Pelvic Pain

Ortiz, R., Gemmill, J. A. L., Sinaii, N., Stegmann, B., Khachikyan, I., Chrousos, G., Segars, J. & Stratton, P., 2020, (Accepted/In press) In : Reproductive Sciences.

Research output: Contribution to journalArticle

2017

Does the Presence of Blood in the Catheter or the Degree of Difficulty of Embryo Transfer Affect Live Birth?

Plowden, T. C., Hill, M. J., Miles, S. M., Hoyt, B., Yauger, B., Segars, J. H., Csokmay, J. M. & Chason, R. J., May 1 2017, In : Reproductive Sciences. 24, 5, p. 726-730 5 p.

Research output: Contribution to journalArticle