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  • Robert A Wise
2018

Development of a novel digital breath-activated inhaler: Initial particle size characterization and clinical testing

Kesten, S., Israel, E., Li, G., Mitchell, J., Wise, R. A. & Stern, T., Dec 1 2018, In : Pulmonary Pharmacology and Therapeutics. 53, p. 27-32 6 p.

Research output: Contribution to journalArticle

2017

A new measure to assess asthma's effect on quality of life from the patient's perspective

Wilson, S. R., Mulligan, M. J., Ayala, E., Chausow, A., Huang, Q., Knowles, S. B., Gummidipundi, S., Castro, M. & Wise, R. A., 2017, (Accepted/In press) In : Journal of Allergy and Clinical Immunology.

Research output: Contribution to journalArticle

2016

Tiotropium safety in ‘real–world’ populations: Response to Schmiedl, et al. in the British Journal of Clinical Pharmacology

Wise, R., Anzueto, A., Dahl, R., Dusser, D. & Calverley, P., 2016, In : British Journal of Clinical Pharmacology. p. 562-563 2 p.

Research output: Contribution to journalLetter

2017

Determinants of exacerbation risk in patients with COPD in the TIOSPIR study

Calverley, P. M. A., Tetzlaff, K., Dusser, D., Wise, R. A., Mueller, A., Metzdorf, N. & Anzueto, A., Nov 29 2017, In : International Journal of COPD. 12, p. 3391-3405 15 p.

Research output: Contribution to journalArticle

Examining the Effects of Age on Health Outcomes of Chronic Obstructive Pulmonary Disease: Results From the Genetic Epidemiology of Chronic Obstructive Pulmonary Disease Study and Evaluation of Chronic Obstructive Pulmonary Disease Longitudinally to Identify Predictive Surrogate Endpoints Cohorts

Parulekar, A. D., Martinez, C., Tsai, C. L., Locantore, N., Atik, M., Yohannes, A. M., Kao, C. C., Al-Azzawi, H., Mohsin, A., Wise, R. A., Foreman, M. G., Demeo, D. L., Regan, E. A., Make, B. J., Boriek, A. M., Wiener, L. E. & Hanania, N. A., Dec 1 2017, In : Journal of the American Medical Directors Association. 18, 12, p. 1063-1068 6 p.

Research output: Contribution to journalArticle

2016

Mycophenolate mofetil versus oral cyclophosphamide in scleroderma-related interstitial lung disease (SLS II): a randomised controlled, double-blind, parallel group trial

Tashkin, D. P., Roth, M. D., Clements, P. J., Furst, D. E., Khanna, D., Kleerup, E. C., Goldin, J., Arriola, E., Volkmann, E. R., Kafaja, S., Silver, R., Steen, V., Strange, C., Wise, R., Wigley, F., Mayes, M., Riley, D. J., Hussain, S., Assassi, S., Hsu, V. M. & 24 others, Patel, B., Phillips, K., Martinez, F., Golden, J., Connolly, M. K., Varga, J., Dematte, J., Hinchcliff, M. E., Fischer, A., Swigris, J., Meehan, R., Theodore, A., Simms, R., Volkov, S., Schraufnagel, D. E., Scholand, M. B., Frech, T., Molitor, J. A., Highland, K., Read, C. A., Fritzler, M. J., Kim, G. H. J., Tseng, C. H. & Elashoff, R. M., Sep 1 2016, In : The Lancet Respiratory Medicine. 4, 9, p. 708-719 12 p.

Research output: Contribution to journalArticle

Gastro-oesophageal reflux and worse asthma control in obese children: A case of symptom misattribution?

Lang, J. E., Hossain, J., Holbrook, J. T., Teague, W. G., Gold, B. D., Wise, R. A. & Lima, J. J., Mar 2016, In : Thorax. 71, 3, p. 238-246 9 p.

Research output: Contribution to journalArticle

2018

Effect of obesity on sinonasal disease in asthma

Kanagalingam, S., Shehab, S. S., Kaminsky, D. A., Wise, R. A., Lang, J. E. & Dixon, A. E., May 4 2018, In : Journal of Asthma. 55, 5, p. 525-531 7 p.

Research output: Contribution to journalArticle

Anemia and adverse outcomes in a chronic obstructive pulmonary disease population with a high burden of comorbidities an analysis from SPIROMICS

on behalf of the SPIROMICS Investigators, Jun 2018, In : Annals of the American Thoracic Society. 15, 6, p. 710-717 8 p.

Research output: Contribution to journalArticle

Genome-wide association study of lung function and clinical implication in heavy smokers

for the SPIROMICS Research Group, Aug 1 2018, In : BMC medical genetics. 19, 1, 134.

Research output: Contribution to journalArticle

2020

Reduction in all-cause mortality with fluticasone furoate/umeclidinium/vilanterol in patients with chronic obstructive pulmonary disease

Lipson, D. A., Crim, C., Criner, G. J., Day, N. C., Dransfield, M. T., Halpin, D. M. G., Han, M. L. K., Jones, C. E., Kilbride, S., Lange, P., Lomas, D. A., Lettis, S., Manchester, P., Martin, N., Midwinter, D., Morris, A., Pascoe, S. J., Singh, D., Wise, R. A. & Martinez, F. J., Jun 15 2020, In : American journal of respiratory and critical care medicine. 201, 12, p. 1508-1516 9 p.

Research output: Contribution to journalArticle

Open Access

Association of Guideline-Recommended COPD Inhaler Regimens With Mortality, Respiratory Exacerbations, and Quality of Life: A Secondary Analysis of the Long-Term Oxygen Treatment Trial

Keller, T., Spece, L. J., Donovan, L. M., Udris, E., Coggeshall, S. S., Griffith, M., Bryant, A. D., Casaburi, R., Cooper, J. A., Criner, G. J., Diaz, P. T., Fuhlbrigge, A. L., Gay, S. E., Kanner, R. E., Martinez, F. J., Panos, R. J., Shade, D., Sternberg, A., Stibolt, T., Stoller, J. K. & 5 others, Tonascia, J., Wise, R., Yusen, R. D., Au, D. H. & Feemster, L. C., Aug 2020, In : CHEST. 158, 2, p. 529-538 10 p.

Research output: Contribution to journalArticle

Open Access
2019

The St. George's Respiratory Questionnaire Definition of Chronic Bronchitis May Be a Better Predictor of COPD Exacerbations Compared With the Classic Definition

COPDGene Investigators, Oct 2019, In : CHEST. 156, 4, p. 685-695 11 p.

Research output: Contribution to journalArticle

2018

Lobar Emphysema Distribution Is Associated With 5-Year Radiological Disease Progression

for the, COPDGene Investigators & COPDGene Investigators, Jan 2018, In : CHEST. 153, 1, p. 65-76 12 p.

Research output: Contribution to journalArticle

2019

Effect of Aclidinium Bromide on Major Cardiovascular Events and Exacerbations in High-Risk Patients With Chronic Obstructive Pulmonary Disease: The ASCENT-COPD Randomized Clinical Trial

Wise, R. A., Chapman, K. R., Scirica, B. M., Bhatt, D. L., Daoud, S. Z., Zetterstrand, S., Reisner, C. & Gil, E. G., May 7 2019, In : JAMA. 321, 17, p. 1693-1701 9 p.

Research output: Contribution to journalArticle

2016

Urbanization and daily exposure to biomass fuel smoke both contribute to chronic bronchitis risk in a population with low prevalence of daily tobacco smoking

Miele, C. H., Jaganath, D., Miranda, J. J., Bernabe-Ortiz, A., Gilman, R. H., Johnson, C. M., Diette, G. B., Wise, R. A. & Checkley, W., Mar 3 2016, In : COPD: Journal of Chronic Obstructive Pulmonary Disease. 13, 2, p. 186-195 10 p.

Research output: Contribution to journalArticle

2017

Electronic Cigarette Use in US Adults at Risk for or with COPD: Analysis from Two Observational Cohorts

For Copdgene And Spiromics Investigators, Dec 1 2017, In : Journal of general internal medicine. 32, 12, p. 1315-1322 8 p.

Research output: Contribution to journalArticle

Fluctuation analysis of peak expiratory flow and its association with treatment failure in asthma

Kaminsky, D. A., Wang, L. L., Bates, J. H. T., Thamrin, C., Shade, D. M., Dixon, A. E., Wise, R. A., Peters, S. & Irvin, C. G., Apr 15 2017, In : American journal of respiratory and critical care medicine. 195, 8, p. 993-999 7 p.

Research output: Contribution to journalArticle

2018

Association of thrombocytosis with COPD morbidity: The SPIROMICS and COPDGene cohorts

and for the SPIROMICS and COPDGene Investigators, Jan 26 2018, In : Respiratory research. 19, 1, 20.

Research output: Contribution to journalArticle

2017

Prevalence and risk factors of restrictive spirometry in a cohort of Peruvian adults

Siddharthan, T., Grigsby, M., Miele, C. H., Bernabe-Ortiz, A., Miranda, J. J., Gilman, R. H., Wise, R. A., Porter, J. C., Hurst, J. R. & Checkley, W., Sep 1 2017, In : International Journal of Tuberculosis and Lung Disease. 21, 9, p. 1062-1068 7 p.

Research output: Contribution to journalArticle

Effect of an integrated pest management intervention on asthma symptoms among mouse-sensitized children and adolescents with asthma a randomized clinical trial

Matsui, E. C., Perzanowski, M., Peng, R. D., Wise, R. A., Balcer-Whaley, S., Newman, M., Cunningham, A., Divjan, A., Bollinger, M. E., Zhai, S., Chew, G., Miller, R. L. & Phipatanakul, W., Mar 14 2017, In : JAMA - Journal of the American Medical Association. 317, 10, p. 1027-1036 10 p.

Research output: Contribution to journalArticle

2016

Increased Cardiometabolic Risk and Worsening Hypoxemia at High Altitude

Miele, C. H., Schwartz, A. R., Gilman, R. H., Pham, L., Wise, R. A., Davila-Roman, V. G., Jun, J. C., Polotsky, V. Y., Miranda, J. J., Leon-Velarde, F. & Checkley, W., Jun 1 2016, In : High Altitude Medicine and Biology. 17, 2, p. 93-100 8 p.

Research output: Contribution to journalArticle

Identifying biomarkers for asthma diagnosis using targeted metabolomics approaches

Checkley, W., Deza, M. P., Klawitter, J., Romero, K. M., Klawitter, J., Pollard, S. L., Wise, R. A., Christians, U. & Hansel, N. N., Dec 1 2016, In : Respiratory Medicine. 121, p. 59-66 8 p.

Research output: Contribution to journalArticle

2020

Longitudinal assessment of interstitial lung disease in single lung transplant recipients with scleroderma

Hinze, A. M., Lin, C. T., Hussien, A. F., Perin, J., Venado, A., Golden, J. A., Boin, F., Brown, R. H., Wise, R. A. & Wigley, F. M., Apr 1 2020, In : Rheumatology (United Kingdom). 59, 4, p. 790-798 9 p.

Research output: Contribution to journalArticle

2016

Chronic exposure to biomass fuel smoke and markers of endothelial inflammation

Caravedo, M. A., Herrera, P. M., Mongilardi, N., de Ferrari, A., Davila-Roman, V. G., Gilman, R. H., Wise, R. A., Miele, C. H., Miranda, J. J. & Checkley, W., Oct 1 2016, In : Indoor Air. 26, 5, p. 768-775 8 p.

Research output: Contribution to journalArticle

2018

Effectiveness-implementation of COPD case finding and self-management action plans in low- and middle-income countries: Global excellence in COPD outcomes (GECo) study protocol

Siddharthan, T., Pollard, S. L., Quaderi, S. A., Mirelman, A. J., Cárdenas, M. K., Kirenga, B., Rykiel, N. A., Miranda, J. J., Shrestha, L., Chandyo, R. K., Cattamanchi, A., Michie, S., Barber, J., Checkley, W., Hurst, J. R., Hurst, J. R., Anastasiou, Z., Pollard, S. L., Morgan, B., Rykiel, N. A. & 15 others, Grigsby, M., Robertson, N., Wise, R. A., Yogi, K. N., Sharma, A., Chandyo, R. K., Alupo, P., Muwonge, D., Mawanda, D., Nassali, F., Kalyesubula, R., Mirelman, A. J., Soares, M., Flores-Flores, O. & Romani-Huacani, E., Oct 19 2018, In : Trials. 19, 1, 571.

Research output: Contribution to journalArticle

2019

Lung cancer-related mortality with inhaled insulin or a comparator: Follow-up study of patients previously enrolled in exubera controlled clinical trials (FUSE) final results

Gatto, N. M., Koralek, D. O., Bracken, M. B., Duggan, W. T., Lem, J., Klioze, S., Koch, G. G., Wise, R. A., Cohen, R. B. & Jackson, N. C., Sep 1 2019, In : Diabetes care. 42, 9, p. 1708-1715 8 p.

Research output: Contribution to journalArticle

2018

Does Obesity Increase Respiratory Tract Infections in Patients with Asthma?

Tang, M., Henderson, R. J., Holbrook, J. T., Que, L. G., Mathews, A. M., Wise, R. A., Dixon, A. E., Peters, S. P., Rogers, L., Smith, L. J., Teague, W. G. & Lang, J. E., Jan 1 2018, (Accepted/In press) In : Journal of Allergy and Clinical Immunology: In Practice.

Research output: Contribution to journalArticle

2017

Higher BMI is associated with higher expiratory airflow normalised for lung volume (FEF25–75/FVC) in COPD

Abston, E., Comellas, A., Reed, R. M., Kim, V., Wise, R. A., Brower, R., Fortis, S., Beichel, R., Bhatt, S., Zabner, J., Newell, J., Hoffman, E. A. & Eberlein, M., Oct 1 2017, In : BMJ Open Respiratory Research. 4, 1, e000231.

Research output: Contribution to journalArticle

2018
Open Access
2020

Methodology and baseline characteristics of a randomized controlled trial testing a health care professional and peer-support program for patients with chronic obstructive pulmonary disease: The BREATHE2 study

Aboumatar, H., Naqibuddin, M., Neiman, J., Saunders, J., Kim, S., Chaudhry, H., Garcia-Morales, E., Robinson, N., McBurney, M., Jager, L., Ajayi, T., Bone, L., Chung, S., Farrell, B., Joo Jin, H., Linnell, J., Pirfo, M., Rand, C., Riley, P., Salvaterra, C. & 3 others, Shea, K., Singh, J. & Wise, R., Jul 2020, In : Contemporary Clinical Trials. 94, 106023.

Research output: Contribution to journalArticle

2017

Sex-based genetic association study identifies celsr1 as a possible chronic obstructive pulmonary disease risk locus among women

the COPDGene and Evaluation of COPD Longitudinally to Identify Predictive Surrogate End-Points Investigators, Mar 1 2017, In : American journal of respiratory cell and molecular biology. 56, 3, p. 332-341 10 p.

Research output: Contribution to journalArticle

2016

Implementation of a COPD Screening Questionnaire in an Outpatient HIV Clinic

Lambert, A. A., Drummond, M. B., Kisalu, A., Moxley, J., Keruly, J., Moore, R. D., Wise, R. A. & Kirk, G. D., Nov 1 2016, In : COPD: Journal of Chronic Obstructive Pulmonary Disease. 13, 6, p. 767-772 6 p.

Research output: Contribution to journalArticle

2018

The long-term oxygen treatment trial for chronic obstructive pulmonary disease: Rationale, design, and lessons learned

for the LOTT Research Group, Jan 2018, In : Annals of the American Thoracic Society. 15, 1, p. 89-101 13 p.

Research output: Contribution to journalArticle

2019

Prevalencia de enfermedades respiratorias crónicas en zonas urbanas y rurales de uganda

Translated title of the contribution: Prevalence of chronic respiratory disease in urban and rural ugandaSiddharthan, T., Grigsby, M., Morgan, B., Kalyesubula, R., Wise, R. A., Kirengab, B. & Checkleya, W., May 2019, In : Bulletin of the World Health Organization. 97, 5, p. 318-327 10 p.

Research output: Contribution to journalArticle

Open Access
2016

Effect of continuous positive airway pressure on airway reactivity in asthma: A randomized, sham-controlled clinical trial

American Lung Association Airways Clinical Research Centers, Nov 2016, In : Annals of the American Thoracic Society. 13, 11, p. 1940-1950 11 p.

Research output: Contribution to journalArticle

Effect of intranasal corticosteroids on allergic airway disease in asthma

Dixon, A. E., Castro, M., Gerald, L. B., Holbrook, J. T., Henderson, R. J., Casale, T. B., Irvin, C. G., Black, K., Wise, R. A. & Sugar, E., Sep 1 2016, (Accepted/In press) In : Journal of Allergy and Clinical Immunology: In Practice.

Research output: Contribution to journalArticle

2019
Open Access
2018

Longitudinal phenotypes and mortality in preserved ratio impaired spirometry in the COPDGene study

For the COPDGene Investigators, Dec 1 2018, In : American journal of respiratory and critical care medicine. 198, 11, p. 1397-1405 9 p.

Research output: Contribution to journalArticle

2016

Patterns of growth and decline in lung function in Persistent Childhood Asthma

for the CAMP Research Group, May 12 2016, In : New England Journal of Medicine. 374, 19, p. 1842-1852 11 p.

Research output: Contribution to journalArticle

2017

American thoracic society/national heart, lung, and blood institute asthma-chronic obstructive pulmonary disease overlap workshop report

Woodruff, P. G., Van Den Berge, M., Boucher, R. C., Brightling, C., Burchard, E. G., Christenson, S. A., Han, M. K., Holtzman, M. J., Kraft, M., Lynch, D. A., Martinez, F. D., Reddel, H. K., Sin, D. D., Washko, G. R., Wenzel, S. E., Punturieri, A., Freemer, M. M. & Wise, R. A., Aug 1 2017, In : American journal of respiratory and critical care medicine. 196, 3, p. 375-381 7 p.

Research output: Contribution to journalArticle

2019

Blood eosinophils and treatment response with triple and dual combination therapy in chronic obstructive pulmonary disease: analysis of the IMPACT trial

Pascoe, S., Barnes, N., Brusselle, G., Compton, C., Criner, G. J., Dransfield, M. T., Halpin, D. M. G., Han, M. L. K., Hartley, B., Lange, P., Lettis, S., Lipson, D. A., Lomas, D. A., Martinez, F. J., Papi, A., Roche, N., van der Valk, R. J. P., Wise, R. & Singh, D., Sep 2019, In : The Lancet Respiratory Medicine. 7, 9, p. 745-756 12 p.

Research output: Contribution to journalArticle

2018

Seasonal variations in exacerbations and deaths in patients with COPD during the TIOSPIR® trial

Wise, R. A., Calverley, P. M. A., Carter, K., Clerisme-Beaty, E., Metzdorf, N. & Anzueto, A., Feb 14 2018, In : International Journal of COPD. 13, p. 605-616 12 p.

Research output: Contribution to journalArticle

2017

The author replies

Wise, R. A., Jan 19 2017, In : New England Journal of Medicine. 376, 3, p. 287 1 p.

Research output: Contribution to journalLetter

2018

Long-term evaluation of the effects of Aclidinium bromide on major adverse cardiovascular events and COPD exacerbations in patients with moderate to very severe COPD: Rationale and design of the ASCENT COPD study

Wise, R. A., Chapman, K. R., Scirica, B. M., Schoenfeld, D. A., Bhatt, D. L., Daoud, S. Z., Seoane, B., Reisner, C. & Gil, E. G., 2018, In : Chronic Obstructive Pulmonary Diseases. 5, 1, p. 5-15 11 p.

Research output: Contribution to journalArticle

2016

National priorities for perioperative research in South Africa

South African Perioperative Research Group national research priority-setting working group, May 2016, In : South African Medical Journal. 106, 5, p. 485-488 4 p.

Research output: Contribution to journalArticle

Open Access
2017

Discordance in investigator-reported and adjudicated sudden death in TIOSPIR

Wise, R. A., Kowey, P. R., Austen, G., Mueller, A., Metzdorf, N., Fowler, A. & McGarvey, L. P., Jan 1 2017, In : ERS Monograph. 3, 1, 00073-2016.

Research output: Contribution to journalArticle

2018

Efficacy of Mycophenolate Mofetil and Oral Cyclophosphamide on Skin Thickness: Post Hoc Analyses From Two Randomized Placebo-Controlled Trials

Participants in the Scleroderma Lung Study I and members of the Scleroderma Lung Study II Research Group, Mar 2018, In : Arthritis Care and Research. 70, 3, p. 439-444 6 p.

Research output: Contribution to journalArticle

2016

Efficacy and safety of ipratropium bromide/albuterol compared with albuterol in patients with moderate-to-severe asthma: A randomized controlled trial

Donohue, J. F., Wise, R. A., Busse, W. W., Garfinkel, S., Zubek, V. B., Ghafouri, M., Manuel, R. C., Schlenker-Herceg, R. & Bleecker, E. R., 2016, In : BMC Pulmonary Medicine. 16, 1, 65.

Research output: Contribution to journalArticle

2020

Development of the Asthma Impairment and Risk Questionnaire (AIRQ): A Composite Control Measure

US PRECISION Advisory Board, Jul 1 2020, In : Journal of Allergy and Clinical Immunology: In Practice. 8, 7, p. 2263-2274.e5

Research output: Contribution to journalArticle