Find Research Outputs

Search in all content

Filters for Research Output

Search concepts
Selected Filters

Publication Year

  • 2019
  • 2018
  • 2017
  • 2016

Author

  • Bruce Trock
2017

Prostate mri prior to radical prostatectomy: Effects on nerve sparing and pathological margin status

Druskin, S. C., Liu, J. J., Young, A., Feng, Z., Dianat, S. S., Ludwig, W. W., Trock, B., Macura, K. & Pavlovich, C., Apr 18 2017, In : Research and Reports in Urology. 9, p. 55-63 9 p.

Research output: Contribution to journalArticle

Molecular Analysis of Low Grade Prostate Cancer Using a Genomic Classifier of Metastatic Potential

Klein, E. A., Santiago-Jiménez, M., Yousefi, K., Robbins, B. A., Schaeffer, E. M., Trock, B., Tosoian, J., Haddad, Z., Ra, S., Karnes, R. J., Jenkins, R. B., Cheville, J. C., Den, R. B., Dicker, A. P., Davicioni, E., Freedland, S. J. & Ross, A. E., Jan 1 2017, In : Journal of Urology. 197, 1, p. 122-128 7 p.

Research output: Contribution to journalArticle

Molecular Signatures and Shared Decision-Making for Precision Medicine

Trock, B. & Hinman, F., 2017, (Accepted/In press) In : Urology.

Research output: Contribution to journalArticle

2016
2018

Clinical utility of assessing PTEN and ERG protein expression in prostate cancer patients: a proposed method for risk stratification

Bismar, T. A., Hegazy, S., Feng, Z., Yu, D., Donnelly, B., Palanisamy, N. & Trock, B., Jan 1 2018, (Accepted/In press) In : Journal of Cancer Research and Clinical Oncology.

Research output: Contribution to journalArticle

2016

Efficacy of post-operative radiation in a prostatectomy cohort adjusted for clinical and genomic risk

Ross, A. E., Den, R. B., Yousefi, K., Trock, B. J., Tosoian, J., Davicioni, E., Thompson, D. J. S., Choeurng, V., Haddad, Z., Tran, P. T., Trabulsi, E. J., Gomella, L. G., Lallas, C. D., Abdollah, F., Feng, F. Y., Klein, E. A., Dicker, A. P., Freedland, S. J., Karnes, R. J. & Schaeffer, E. M., Sep 1 2016, In : Prostate Cancer and Prostatic Diseases. 19, 3, p. 277-282 6 p.

Research output: Contribution to journalArticle

2018

Predictors of a successful primary bladder closure in cloacal exstrophy: A multivariable analysis

Jayman, J., Tourchi, A., Feng, Z., Trock, B., Maruf, M., Benz, K., Kasprenski, M., Baumgartner, T., Friedlander, D., Sponseller, P. D. & Gearhart, J. P., Jan 1 2018, (Accepted/In press) In : Journal of Pediatric Surgery.

Research output: Contribution to journalArticle

2017

Expert consensus document: Semantics in active surveillance for men with localized prostate cancer-results of a modified Delphi consensus procedure

Movember Foundation's Global Action Plan Prostate Cancer Active Surveillance (GAP3) consortium, May 1 2017, In : Nature Reviews Urology. 14, 5, p. 312-322 11 p.

Research output: Contribution to journalReview article

Open Access

The Impact of Downgrading from Biopsy Gleason 7 to Prostatectomy Gleason 6 on Biochemical Recurrence and Prostate Cancer Specific Mortality

Ham, W. S., Chalfin, H. J., Feng, Z., Trock, B., Epstein, J. I., Cheung, C., Humphreys, E., Partin, A. W. & Han, M., Apr 1 2017, In : Journal of Urology. 197, 4, p. 1060-1067 8 p.

Research output: Contribution to journalArticle

2019
2017

Rapid Loss of RNA Detection by in Situ Hybridization in Stored Tissue Blocks and Preservation by Cold Storage of Unstained Slides

Baena-Del Valle, J. A., Zheng, Q., Hicks, J. L., Fedor, H., Trock, B., Morrissey, C., Corey, E., Cornish, T. C., Sfanos, K. & Demarzo, A. M., Nov 1 2017, In : American Journal of Clinical Pathology. 148, 5, p. 398-415 18 p.

Research output: Contribution to journalArticle

2016

Molecular Triage of Premalignant Lesions in Liquid-Based Cervical Cytology and Circulating Cell-Free DNA from Urine, Using a Panel of Methylated Human Papilloma Virus and Host Genes

Guerrero-Preston, R., Valle, B. L., Jedlicka, A. E., Turaga, N., Folawiyo, O., Pirini, F., Lawson, F., Vergura, A., Noordhuis, M., Dziedzic, A., Perez, G., Renehan, M., Guerrero-Diaz, C., Jesus Rodríguez, E. D., Diaz-Montes, T., Orengo, J. R., Mendez, K., Romaguera, J., Trock, B., Florea, L. D. & 1 others, Sidransky, D., Dec 1 2016, In : Cancer Prevention Research. 9, 12, p. 915-924 10 p.

Research output: Contribution to journalArticle

2019

ARv7 Represses Tumor-Suppressor Genes in Castration-Resistant Prostate Cancer

Cato, L., de Tribolet-Hardy, J., Lee, I., Rottenberg, J. T., Coleman, I., Melchers, D., Houtman, R., Xiao, T., Li, W., Uo, T., Sun, S., Kuznik, N. C., Göppert, B., Ozgun, F., van Royen, M. E., Houtsmuller, A. B., Vadhi, R., Rao, P. K., Li, L., Balk, S. P. & 15 others, Den, R. B., Trock, B. J., Karnes, R. J., Jenkins, R. B., Klein, E. A., Davicioni, E., Gruhl, F. J., Long, H. W., Liu, X. S., Cato, A. C. B., Lack, N. A., Nelson, P. S., Plymate, S. R., Groner, A. C. & Brown, M., Mar 18 2019, In : Cancer cell. 35, 3, p. 401-413.e6

Research output: Contribution to journalArticle

Genetic alterations detected in cell-free DNA are associated with enzalutamide and abiraterone resistance in castration-resistant prostate cancer

Torquato, S., Pallavajjala, A., Goldstein, A., Toro, P. V., Silberstein, J. L., Lee, J., Nakazawa, M., Waters, I., Chu, D., Shinn, D., Groginski, T., Hughes, R. M., Simons, B., Khan, H., Feng, Z., Carducci, M. A., Paller, C. J., Denmeade, S. R., Kressel, B., Eisenberger, M. A. & 4 others, Antonarakis, E. S., Trock, B. J., Park, B. H. & Hurley, P. J., Jan 1 2019, In : JCO Precision Oncology. 3

Research output: Contribution to journalArticle

Open Access
2017

Validation of a Genomic Risk Classifier to Predict Prostate Cancer-specific Mortality in Men with Adverse Pathologic Features

Karnes, R. J., Choeurng, V., Ross, A. E., Schaeffer, E. M., Klein, E. A., Freedland, S. J., Erho, N., Yousefi, K., Takhar, M., Davicioni, E., Cooperberg, M. R. & Trock, B., 2017, (Accepted/In press) In : European Urology.

Research output: Contribution to journalArticle

Ability of a Genomic Classifier to Predict Metastasis and Prostate Cancer-specific Mortality after Radiation or Surgery based on Needle Biopsy Specimens

Nguyen, P. L., Haddad, Z., Ross, A. E., Martin, N. E., Deheshi, S., Lam, L. L. C., Chelliserry, J., Tosoian, J. J., Lotan, T. L., Spratt, D. E., Stoyanova, R. S., Punnen, S., Ong, K., Buerki, C., Aranes, M., Kolisnik, T., Margrave, J., Yousefi, K., Choeurng, V., Davicioni, E. & 6 others, Trock, B. J., Kane, C. J., Pollack, A., Davis, J. W., Feng, F. Y. & Klein, E. A., Nov 2017, In : European Urology. 72, 5, p. 845-852 8 p.

Research output: Contribution to journalArticle

Prediction of pathological stage based on clinical stage, serum prostate-specific antigen, and biopsy Gleason score: Partin Tables in the contemporary era

Tosoian, J. J., Chappidi, M., Feng, Z., Humphreys, E. B., Han, M., Pavlovich, C. P., Epstein, J. I., Partin, A. W. & Trock, B. J., May 1 2017, In : BJU International. 119, 5, p. 676-683 8 p.

Research output: Contribution to journalArticle

2016

Risk prediction tool for grade re-classification in men with favourable-risk prostate cancer on active surveillance

Mamawala, M. M., Rao, K., Landis, P., Epstein, J. I., Trock, B., Tosoian, J. J., Pienta, K. & Carter, H. B., 2016, (Accepted/In press) In : BJU International.

Research output: Contribution to journalArticle

2018

Comparative effectiveness of management options for patients with small renal masses: a prospective cohort study

Alam, R., Patel, H. D., Osumah, T., Srivastava, A., Gorin, M., Johnson, M., Trock, B., Chang, P., Wagner, A. A., McKiernan, J. M., Allaf, M. E. & Pierorazio, P. M., Jan 1 2018, (Accepted/In press) In : BJU International.

Research output: Contribution to journalArticle

The Movember Foundation's GAP3 cohort: a profile of the largest global prostate cancer active surveillance database to date

Movember Foundation's Global Action Plan Prostate Cancer Active Surveillance (GAP3) consortium, May 2018, In : BJU International. 121, 5, p. 737-744 8 p.

Research output: Contribution to journalArticle

2016

Clinical validation of the 2005 isup gleason grading system in a cohort of intermediate and high risk men undergoing radical prostatectomy

Faraj, S. F., Bezerra, S. M., Yousefi, K., Fedor, H., Glavaris, S., Han, M., Partin, A. W., Humphreys, E., Tosoian, J., Johnson, M. H., Davicioni, E., Trock, B. J., Schaeffer, E. M., Ross, A. E. & Netto, G. J., Jan 5 2016, In : PloS one. 11, 1, e0146189.

Research output: Contribution to journalArticle

2019

Re: Comparative effectiveness of management options for patients with small renal masses: A prospective cohort study

Alam, R., Patel, H. D., Osumah, T., Srivastava, A., Gorin, M. A., Johnson, M. H., Trock, B. J., Chang, P., Wagner, A. A., McKiernan, J. M., Allaf, M. E. & Pierorazio, P. M., Mar 1 2019, In : Journal of Urology. 201, 3, 1 p.

Research output: Contribution to journalComment/debate

PTEN status assessment in the Johns Hopkins active surveillance cohort

Tosoian, J. J., Guedes, L. B., Morais, C. L., Mamawala, M., Ross, A. E., De Marzo, A. M., Trock, B. J., Han, M., Carter, H. B. & Lotan, T. L., Mar 1 2019, In : Prostate Cancer and Prostatic Diseases. 22, 1, p. 176-181 6 p.

Research output: Contribution to journalArticle

2018

Growth Kinetics of Small Renal Masses on Active Surveillance: Variability and Results from the DISSRM Registry

Uzosike, A. C., Patel, H. D., Alam, R., Schwen, Z. R., Gupta, M., Gorin, M. A., Johnson, M. H., Gausepohl, H., Riffon, M. F., Trock, B. J., Chang, P., Wagner, A. A., McKiernan, J. M., Allaf, M. E. & Pierorazio, P. M., Mar 2018, In : Journal of Urology. 199, 3, p. 641-648 8 p.

Research output: Contribution to journalArticle

2019

The dual-staged pathway for closure in cloacal exstrophy: Successful evolution in collaborative surgical practice

Jayman, J., Michaud, J., Maruf, M., Trock, B., Kasprenski, M., Sponseller, P. D. & Gearhart, J. P., Jan 1 2019, In : Journal of pediatric surgery.

Research output: Contribution to journalArticle

2017

Detection fidelity of AR mutations in plasma derived cell-free DNA

Goldstein, A., Toro, P. V., Lee, J., Silberstein, J. L., Nakazawa, M., Waters, I., Cravero, K., Chu, D., Cochran, R. L., Kim, M., Shinn, D., Torquato, S., Hughes, R. M., Pallavajjala, A., Carducci, M. A., Paller, C. J., Denmeade, S. R., Kressel, B., Trock, B. J., Eisenberger, M. A. & 3 others, Antonarakis, E. S., Park, B. H. & Hurley, P. J., Jan 1 2017, In : Oncotarget. 8, 9, p. 15651-15662 12 p.

Research output: Contribution to journalArticle

2018

Predictors and outcomes of perioperative blood transfusions in classic bladder exstrophy repair: A single institution study

Maruf, M., Jayman, J., Kasprenski, M., Benz, K., Feng, Z., Friedlander, D., Baumgartner, T., Trock, B., DiCarlo, H., Sponseller, P. D. & Gearhart, J. P., Jan 1 2018, (Accepted/In press) In : Journal of Pediatric Urology.

Research output: Contribution to journalArticle

2019

Older Age Predicts Biopsy and Radical Prostatectomy Grade Reclassification to Aggressive Prostate Cancer in Men on Active Surveillance

Druskin, S. C., Mamawala, M., Tosoian, J. J., Epstein, J. I., Pavlovich, C., Carter, H. B. & Trock, B., Jan 1 2019, In : The Journal of Urology. 201, 1, p. 98-104 7 p.

Research output: Contribution to journalArticle

Low tristetraprolin expression is associated with lethal prostate cancer

Gerke, T., Beltran, H., Wang, X., Lee, G. S. M., Sboner, A., Karnes, R. J., Klein, E. A., Davicioni, E., Yousefi, K., Ross, A. E., Bornigen, D., Huttenhower, C., Mucci, L. A., Trock, B. J. & Sweeney, C. J., Mar 2019, In : Cancer Epidemiology Biomarkers and Prevention. 28, 3, p. 584-590 7 p.

Research output: Contribution to journalArticle

2018

Impact of the SPOP mutant subtype on the interpretation of clinical parameters in prostate cancer

Liu, D., Takhar, M., Alshalalfa, M., Erho, N., Shoag, J., Jenkins, R. B., Karnes, R. J., Ross, A. E., Schaeffer, E. M., Rubin, M. A., Trock, B., Klein, E. A., Den, R. B., Tomlins, S. A., Spratt, D. E., Davicioni, E., Sboner, A. & Barbieri, C. E., Jan 1 2018, In : JCO Precision Oncology. 2

Research output: Contribution to journalArticle

Open Access

Barriers to radiotherapy access at the University College Hospital in Ibadan, Nigeria

Anakwenze, C. P., Ntekim, A., Trock, B., Uwadiae, I. B. & Page, B. R., Aug 1 2017, In : Clinical and Translational Radiation Oncology. 5, p. 1-5 5 p.

Research output: Contribution to journalArticle

Open Access
2016

Utility of Risk Models in Decision Making after Radical Prostatectomy: Lessons from a Natural History Cohort of Intermediate- and High-Risk Men

Ross, A. E., Yousefi, K., Davicioni, E., Ghadessi, M., Johnson, M. H., Sundi, D., Tosoian, J. J., Han, M., Humphreys, E. B., Partin, A. W., Walsh, P. C., Trock, B. J. & Schaeffer, E. M., Mar 1 2016, In : European Urology. 69, 3, p. 496-504 9 p.

Research output: Contribution to journalArticle

New Prostate Cancer Grading System Predicts Long-term Survival Following Surgery for Gleason Score 8-10 Prostate Cancer

Ham, W. S., Chalfin, H. J., Feng, Z., Trock, B., Epstein, J. I., Cheung, C., Humphreys, E., Partin, A. W. & Han, M., 2016, (Accepted/In press) In : European Urology.

Research output: Contribution to journalArticle

2018

Development and validation of a prostate cancer genomic signature that predicts early adt treatment response following radical prostatectomy

Karnes, R. J., Sharma, V., Choeurng, V., Ashab, H. A. D., Erho, N., Alshalalfa, M., Trock, B., Ross, A., Yousefi, K., Tsai, H., Zhao, S. G., Tosoian, J. J., Haddad, Z., Takhar, M., Chang, S. L., Spratt, D. E., Abdollah, F., Jenkins, R. B., Klein, E. A., Nguyen, P. L. & 6 others, Dicker, A. P., Den, R. B., Davicioni, E., Feng, F. Y., Lotan, T. L. & Schaeffer, E. M., Aug 15 2018, In : Clinical Cancer Research. 24, 16, p. 3908-3916 9 p.

Research output: Contribution to journalArticle

2019

Predicting Biopsy Outcomes During Active Surveillance for Prostate Cancer: External Validation of the Canary Prostate Active Surveillance Study Risk Calculators in Five Large Active Surveillance Cohorts

The Movember Foundations Global Action Plan Prostate Cancer Active Surveillance (GAP) Consortium, Nov 1 2019, In : European Urology. 76, 5, p. 693-702 10 p.

Research output: Contribution to journalArticle

Reasons for Discontinuing Active Surveillance: Assessment of 21 Centres in 12 Countries in the Movember GAP3 Consortium

Members of the Movember Foundation's Global Action Plan Prostate Cancer Active Surveillance GAP3 consortium & Members of the Movember Foundation's Global Action Plan Prostate Cancer Active Surveillance GAP3 consortium, Mar 2019, In : European Urology. 75, 3, p. 523-531 9 p.

Research output: Contribution to journalArticle

2016

SPINK1 Defines a Molecular Subtype of Prostate Cancer in Men with More Rapid Progression in an at Risk, Natural History Radical Prostatectomy Cohort

Johnson, M., Ross, A. E., Alshalalfa, M., Erho, N., Yousefi, K., Glavaris, S., Fedor, H., Han, M., Faraj, S. F., Bezerra, S. M., Netto, G., Partin, A. W., Trock, B., Davicioni, E. & Schaeffer, E. M., Nov 1 2016, In : Journal of Urology. 196, 5, p. 1436-1444 9 p.

Research output: Contribution to journalArticle

2019

Effect of preanalytic variables on an automated PTEN immunohistochemistry assay for prostate cancer

Guedes, L. B., Morais, C. L., Fedor, H., Hicks, J., Gurel, B., Melamed, J., Lee, P., Gopalan, A., Knudsen, B. S., True, L. D., Scher, H. I., Fine, S. W., Trock, B. J., De Marzo, A. M. & Lotan, T. L., Mar 2019, In : Archives of Pathology and Laboratory Medicine. 143, 3, p. 338-348 11 p.

Research output: Contribution to journalArticle

Open Access
2016

Prevalence and Prognostic Significance of PTEN Loss in African-American and European-American Men Undergoing Radical Prostatectomy

Tosoian, J. J., Almutairi, F., Morais, C. L., Glavaris, S., Hicks, J., Sundi, D., Humphreys, E., Han, M., Demarzo, A. M., Ross, A. E., Tomlins, S. A., Schaeffer, E. M., Trock, B. & Lotan, T., 2016, (Accepted/In press) In : European Urology.

Research output: Contribution to journalArticle

2019

Validation of the Decipher Test for predicting adverse pathology in candidates for prostate cancer active surveillance

Kim, H. L., Li, P., Huang, H. C., Deheshi, S., Marti, T., Knudsen, B., Abou-Ouf, H., Alam, R., Lotan, T. L., Lam, L. L. C., du Plessis, M., Davicioni, E., Fleshner, N., Lane, B. R., Ross, A. E., Davis, J. W., Mohler, J. L., Trock, B. J., Klein, E. A., Tosoian, J. J. & 2 others, Hyndman, M. E. & Bismar, T. A., Sep 1 2019, In : Prostate Cancer and Prostatic Diseases. 22, 3, p. 399-405 7 p.

Research output: Contribution to journalArticle

2016

PTEN loss and chromosome 8 alterations in Gleason grade 3 prostate cancer cores predicts the presence of un-sampled grade 4 tumor: Implications for active surveillance

Trock, B. J., Fedor, H., Gurel, B., Jenkins, R. B., Knudsen, B. S., Fine, S. W., Said, J. W., Carter, H. B., Lotan, T. L. & De Marzo, A. M., Jul 1 2016, In : Modern Pathology. 29, 7, p. 764-771 8 p.

Research output: Contribution to journalArticle

2018

Prostate Specific Antigen Testing after Radical Prostatectomy—Can We Stop at 20 Years?

Ludwig, W. W., Feng, Z., Trock, B., Humphreys, E. & Walsh, P., Jan 1 2018, In : Journal of Urology. 199, 1, p. 114-119 6 p.

Research output: Contribution to journalArticle

2017

A Framework for Treatment Decision Making at Prostate Cancer Recurrence

Lange, J. M., Trock, B., Gulati, R. & Etzioni, R., Nov 1 2017, In : Medical Decision Making. 37, 8, p. 905-913 9 p.

Research output: Contribution to journalArticle

2016

A Prospective, Comparative Study of Quality of Life among Patients with Small Renal Masses Choosing Active Surveillance and Primary Intervention

Patel, H. D., Riffon, M. F., Joice, G. A., Johnson, M., Chang, P., Wagner, A. A., McKiernan, J. M., Trock, B., Allaf, M. E. & Pierorazio, P. M., Nov 1 2016, In : Journal of Urology. 196, 5, p. 1356-1362 7 p.

Research output: Contribution to journalArticle

Patterns of Pelvic Lymph Node Dissection at the Time of Radical Prostatectomy for Low-risk Men

Chalfin, H. J., Feng, Z., Trock, B. & Partin, A. W., Oct 13 2016, (Accepted/In press) In : Urology.

Research output: Contribution to journalArticle

2017

Individual patient-level meta-Analysis of the performance of the decipher genomic classifier in high-risk men after prostatectomy to predict development of metastatic disease

Spratt, D. E., Yousefi, K., Deheshi, S., Ross, A. E., Den, R. B., Schaeffer, E. M., Trock, B. J., Zhang, J., Glass, A. G., Dicker, A. P., Abdollah, F., Zhao, S. G., Lam, L. L. C., Du Plessis, M., Choeurng, V., Haddad, Z., Buerki, C., Davicioni, E., Weinmann, S., Freedland, S. J. & 3 others, Klein, E. A., Karnes, R. J. & Feng, F. Y., Jun 20 2017, In : Journal of Clinical Oncology. 35, 18, p. 1991-1998 8 p.

Research output: Contribution to journalArticle