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  • Edward Lakatta
2018

Basal Spontaneous Firing of Rabbit Sinoatrial Node Cells Is Regulated by Dual Activation of PDEs (Phosphodiesterases) 3 and 4

Vinogradova, T. M., Sirenko, S., Lukyanenko, Y. O., Yang, D., Tarasov, K. V., Lyashkov, A. E., Varghese, N. J., Li, Y., Chakir, K., Ziman, B. & Lakatta, E. G., Jun 1 2018, In : Circulation: Arrhythmia and Electrophysiology. 11, 6, e005896.

Research output: Contribution to journalArticle

Dual activation of phosphodiesterases 3 and 4 regulates basal spontaneous beating rate of cardiac pacemaker cells: Role of compartmentalization?

Vinogradova, T. M., Kobrinsky, E. & Lakatta, E., Oct 9 2018, In : Frontiers in Physiology. 9, OCT, 1301.

Research output: Contribution to journalReview article

2019

Aging, MicroRNAs, and Heart Failure

Florio, M. C., Magenta, A., Beji, S., Lakatta, E. G. & Capogrossi, M. C., Jan 1 2019, (Accepted/In press) In : Current Problems in Cardiology.

Research output: Contribution to journalArticle

2018

Reduced vasorin enhances angiotensin II signaling within the aging arterial wall

Pintus, G., Giordo, R., Wang, Y., Zhu, W., Kim, S. H., Zhang, L., Ni, L., Zhang, J., Telljohann, R., McGraw, K. R., Monticone, R. E., Ferris, C., Liu, L., Wang, M. & Lakatta, E. G., Jun 1 2018, In : Oncotarget. 9, 43, p. 27117-27132 16 p.

Research output: Contribution to journalArticle

2019

Cardiotonic Steroids Induce Vascular Fibrosis Via Pressure-Independent Mechanism in NaCl-Loaded Diabetic Rats

Fedorova, O. V., Fadeev, A. V., Grigorova, Y. N., Marshall, C. A., Zernetkina, V., Kolodkin, N. I., Agalakova, N. I., Konradi, A. O., Lakatta, E. G. & Bagrov, A. Y., Nov 1 2019, In : Journal of cardiovascular pharmacology. 74, 5, p. 436-442 7 p.

Research output: Contribution to journalArticle

2018

The reality of getting old

Lakatta, E., Sep 1 2018, In : Nature Reviews Cardiology. 15, 9, p. 499-500 2 p.

Research output: Contribution to journalComment/debate

2020

Synchronized Cardiac Impulses Emerge From Heterogeneous Local Calcium Signals Within and Among Cells of Pacemaker Tissue

Bychkov, R., Juhaszova, M., Tsutsui, K., Coletta, C., Stern, M. D., Maltsev, V. A. & Lakatta, E. G., Aug 2020, In : JACC: Clinical Electrophysiology. 6, 8, p. 907-931 25 p.

Research output: Contribution to journalArticle

2019

Age-related changes of the retinal microvasculature

Orlov, N. V., Coletta, C., van Asten, F., Qian, Y., Ding, J., AlGhatrif, M., Lakatta, E., Chew, E., Wong, W., Swaroop, A., Fiorillo, E., Delitala, A., Marongiu, M., Goldberg, I. G. & Schlessinger, D., May 2019, In : PloS one. 14, 5, e0215916.

Research output: Contribution to journalArticle

Open Access
2018

Segment-specific associations between local haemodynamic and imaging markers of early atherosclerosis at the carotid artery: An in vivo human study

Gallo, D., Bijari, P. B., Morbiducci, U., Qiao, Y., Xie, Y., Etesami, M., Habets, D., Lakatta, E. G., Wasserman, B. A. & Steinman, D. A., Oct 1 2018, In : Journal of the Royal Society Interface. 15, 147, 20180352.

Research output: Contribution to journalArticle

2020

Acclimation to a thermoneutral environment abolishes age-associated alterations in heart rate and heart rate variability in conscious, unrestrained mice

Axsom, J. E., Nanavati, A. P., Rutishauser, C. A., Bonin, J. E., Moen, J. M. & Lakatta, E. G., Feb 1 2020, In : GeroScience. 42, 1, p. 217-232 16 p.

Research output: Contribution to journalArticle

Open Access

Multi-ancestry GWAS of the electrocardiographic PR interval identifies 202 loci underlying cardiac conduction

Ntalla, I., Weng, L. C., Cartwright, J. H., Hall, A. W., Sveinbjornsson, G., Tucker, N. R., Choi, S. H., Chaffin, M. D., Roselli, C., Barnes, M. R., Mifsud, B., Warren, H. R., Hayward, C., Marten, J., Cranley, J. J., Concas, M. P., Gasparini, P., Boutin, T., Kolcic, I., Polasek, O. & 167 others, Rudan, I., Araujo, N. M., Lima-Costa, M. F., Ribeiro, A. L. P., Souza, R. P., Tarazona-Santos, E., Giedraitis, V., Ingelsson, E., Mahajan, A., Morris, A. P., Del Greco M, F., Foco, L., Gögele, M., Hicks, A. A., Cook, J. P., Lind, L., Lindgren, C. M., Sundström, J., Nelson, C. P., Riaz, M. B., Samani, N. J., Sinagra, G., Ulivi, S., Kähönen, M., Mishra, P. P., Mononen, N., Nikus, K., Caulfield, M. J., Dominiczak, A., Padmanabhan, S., Montasser, M. E., O’Connell, J. R., Ryan, K., Shuldiner, A. R., Aeschbacher, S., Conen, D., Risch, L., Thériault, S., Hutri-Kähönen, N., Lehtimäki, T., Lyytikäinen, L. P., Raitakari, O. T., Barnes, C. L. K., Campbell, H., Joshi, P. K., Wilson, J. F., Isaacs, A., Kors, J. A., van Duijn, C. M., Huang, P. L., Gudnason, V., Harris, T. B., Launer, L. J., Smith, A. V., Bottinger, E. P., Loos, R. J. F., Nadkarni, G. N., Preuss, M. H., Correa, A., Mei, H., Wilson, J., Meitinger, T., Müller-Nurasyid, M., Peters, A., Waldenberger, M., Mangino, M., Spector, T. D., Rienstra, M., van de Vegte, Y. J., van der Harst, P., Verweij, N., Kääb, S., Schramm, K., Sinner, M. F., Strauch, K., Cutler, M. J., Fatkin, D., London, B., Olesen, M., Roden, D. M., Benjamin Shoemaker, M., Gustav Smith, J., Biggs, M. L., Bis, J. C., Brody, J. A., Psaty, B. M., Rice, K., Sotoodehnia, N., De Grandi, A., Fuchsberger, C., Pattaro, C., Pramstaller, P. P., Ford, I., Wouter Jukema, J., Macfarlane, P. W., Trompet, S., Dörr, M., Felix, S. B., Völker, U., Weiss, S., Havulinna, A. S., Jula, A., Sääksjärvi, K., Salomaa, V., Guo, X., Heckbert, S. R., Lin, H. J., Rotter, J. I., Taylor, K. D., Yao, J., de Mutsert, R., Maan, A. C., Mook-Kanamori, D. O., Noordam, R., Cucca, F., Ding, J., Lakatta, E. G., Qian, Y., Tarasov, K. V., Levy, D., Lin, H., Newton-Cheh, C. H., Lunetta, K. L., Murray, A. D., Porteous, D. J., Smith, B. H., Stricker, B. H., Uitterlinden, A., van den Berg, M. E., Haessler, J., Jackson, R. D., Kooperberg, C., Peters, U., Reiner, A. P., Whitsel, E. A., Alonso, A., Arking, D. E., Boerwinkle, E., Ehret, G. B., Soliman, E. Z., Avery, C. L., Gogarten, S. M., Kerr, K. F., Laurie, C. C., Seyerle, A. A., Stilp, A., Assa, S., Abdullah Said, M., Yldau van der Ende, M., Lambiase, P. D., Orini, M., Ramirez, J., Van Duijvenboden, S., Arnar, D. O., Gudbjartsson, D. F., Holm, H., Sulem, P., Thorleifsson, G., Thorolfsdottir, R. B., Thorsteinsdottir, U., Benjamin, E. J., Tinker, A., Stefansson, K., Ellinor, P. T., Jamshidi, Y., Lubitz, S. A. & Munroe, P. B., Dec 1 2020, In : Nature communications. 11, 1, 2542.

Research output: Contribution to journalArticle

Open Access
2018

PR interval genome-wide association meta-analysis identifies 50 loci associated with atrial and atrioventricular electrical activity

van Setten, J., Brody, J. A., Jamshidi, Y., Swenson, B. R., Butler, A. M., Campbell, H., Del Greco, F. M., Evans, D. S., Gibson, Q., Gudbjartsson, D. F., Kerr, K. F., Krijthe, B. P., Lyytikäinen, L. P., Müller, C., Müller-Nurasyid, M., Nolte, I. M., Padmanabhan, S., Ritchie, M. D., Robino, A., Smith, A. V. & 106 others, Steri, M., Tanaka, T., Teumer, A., Trompet, S., Ulivi, S., Verweij, N., Yin, X., Arnar, D. O., Asselbergs, F. W., Bader, J. S., Barnard, J., Bis, J., Blankenberg, S., Boerwinkle, E., Bradford, Y., Buckley, B. M., Chung, M. K., Crawford, D., den Hoed, M., Denny, J. C., Dominiczak, A. F., Ehret, G. B., Eijgelsheim, M., Ellinor, P. T., Felix, S. B., Franco, O. H., Franke, L., Harris, T. B., Holm, H., Ilaria, G., Iorio, A., Kähönen, M., Kolcic, I., Kors, J. A., Lakatta, E. G., Launer, L. J., Lin, H., Lin, H. J., Loos, R. J. F., Lubitz, S. A., Macfarlane, P. W., Magnani, J. W., Leach, I. M., Meitinger, T., Mitchell, B. D., Munzel, T., Papanicolaou, G. J., Peters, A., Pfeufer, A., Pramstaller, P. P., Raitakari, O. T., Rotter, J. I., Rudan, I., Samani, N. J., Schlessinger, D., Silva Aldana, C. T., Sinner, M. F., Smith, J. D., Snieder, H., Soliman, E. Z., Spector, T. D., Stott, D. J., Strauch, K., Tarasov, K. V., Thorsteinsdottir, U., Uitterlinden, A. G., Van Wagoner, D. R., Völker, U., Völzke, H., Waldenberger, M., Jan Westra, H., Wild, P. S., Zeller, T., Alonso, A., Avery, C. L., Bandinelli, S., Benjamin, E. J., Cucca, F., Dörr, M., Ferrucci, L., Gasparini, P., Gudnason, V., Hayward, C., Heckbert, S. R., Hicks, A. A., Jukema, J. W., Kääb, S., Lehtimäki, T., Liu, Y., Munroe, P. B., Parsa, A., Polasek, O., Psaty, B. M., Roden, D. M., Schnabel, R. B., Sinagra, G., Stefansson, K., Stricker, B. H., van der Harst, P., van Duijn, C. M., Wilson, J. F., Gharib, S. A., de Bakker, P. I. W., Isaacs, A., Arking, D. E. & Sotoodehnia, N., Dec 1 2018, In : Nature communications. 9, 1, 2904.

Research output: Contribution to journalArticle

A coupled-clock system drives the automaticity of human sinoatrial nodal pacemaker cells

Tsutsui, K., Monfredi, O. J., Sirenko-Tagirova, S. G., Maltseva, L. A., Bychkov, R., Kim, M. S., Ziman, B. D., Tarasov, K. V., Tarasova, Y. S., Zhang, J., Wang, M., Maltsev, A. V., Brennan, J. A., Efimov, I. R., Stern, M. D., Maltsev, V. A. & Lakatta, E., Jun 12 2018, In : Science Signaling. 11, 534, eaap7608.

Research output: Contribution to journalArticle

2017

Causal effect of plasminogen activator inhibitor type 1 on coronary heart disease

CHARGE Consortium Hemostatic Factor Working Group, ICBP Consortium & CHARGE Consortium Subclinical Working Group, Jun 1 2017, In : Journal of the American Heart Association. 6, 6, e004918.

Research output: Contribution to journalArticle

2018

Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

the Million Veteran Program, Oct 1 2018, In : Nature genetics. 50, 10, p. 1412-1425 14 p.

Research output: Contribution to journalArticle

Association of arginine vasopressin with low atrial natriuretic peptide levels, left ventricular remodelling, and outcomes in adults with and without heart failure

Chirinos, J. A., Sardana, M., Oldland, G., Ansari, B., Lee, J., Hussain, A., Mustafa, A., Akers, S. R., Wei, W., Lakatta, E. G. & Fedorova, O. V., Oct 2018, In : ESC Heart Failure. 5, 5, p. 911-919 9 p.

Research output: Contribution to journalArticle

2017

The Pressure of Aging

AlGhatrif, M., Wang, M., Fedorova, O. V., Bagrov, A. Y. & Lakatta, E., Jan 1 2017, In : Medical Clinics of North America. 101, 1, p. 81-101 21 p.

Research output: Contribution to journalReview article

Hemodynamic determinants of the short-term blood pressure variability: Differential roles of arterial stiffness and wave reflection

Hsu, P. F., Cheng, H. M., Sung, S. H., Chuang, S. Y., Lakatta, E., Yin, F. C. P., Chou, P. & Chen, C. H., 2017, In : American Journal of Hypertension. 30, 3, p. 256-263 8 p.

Research output: Contribution to journalArticle

Arterial Stiffness and Risk of Overall Heart Failure, Heart Failure with Preserved Ejection Fraction, and Heart Failure with Reduced Ejection Fraction: The Health ABC Study (Health, Aging, and Body Composition)

Pandey, A., Khan, H., Newman, A. B., Lakatta, E. G., Forman, D. E., Butler, J. & Berry, J. D., Feb 1 2017, In : Hypertension. 69, 2, p. 267-274 8 p.

Research output: Contribution to journalArticle

2018

Calorie restriction curbs proinflammation that accompanies arterial aging, preserving a youthful phenotype

Wang, M., Zhang, L., Zhu, W., Zhang, J., Kim, S. H., Wang, Y., Ni, L., Telljohann, R., Monticone, R. E., McGraw, K., Liu, L., de Cabo, R. & Lakatta, E. G., Sep 1 2018, In : Journal of the American Heart Association. 7, 18, e009112.

Research output: Contribution to journalArticle

2019

Acute salt loading and cardiotonic steroids in resistant hypertension

Emelyanov, I. V., Konradi, A. O., Lakatta, E. G., Fedorova, O. V. & Bagrov, A. Y., 2019, Current Topics in Membranes. Orlov, S. N. (ed.). Academic Press Inc., p. 1-13 13 p. (Current Topics in Membranes; vol. 83).

Research output: Chapter in Book/Report/Conference proceedingChapter

2020

The inherent challenges of classifying senescence−−Response

Calimport, S. R. G., Bentley, B. L., Stewart, C. E., Pawelec, G., Scuteri, A., Vinciguerra, M., Slack, C., Chen, D., Harries, L. W., Marchant, G., Alexander Fleming, G., Conboy, M., Antebi, A., Small, G. W., Gil, J., Lakatta, E. G., Richardson, A., Rosen, C., Nikolich, K., Wyss-Coray, T. & 5 others, Steinman, L., Montine, T., de Magalhães, J. P., Campisi, J. & Church, G., May 8 2020, In : Science. 368, 6491, p. 595-596 2 p.

Research output: Contribution to journalLetter

2017

Longitudinal Association between Serum Uric Acid and Arterial Stiffness: Results from the Baltimore Longitudinal Study of Aging

Canepa, M., Viazzi, F., Strait, J. B., Ameri, P., Pontremoli, R., Brunelli, C., Studenski, S., Ferrucci, L., Lakatta, E. G. & Alghatrif, M., Feb 1 2017, In : Hypertension. 69, 2, p. 228-235 8 p.

Research output: Contribution to journalArticle

2018

Characteristics of healthy vascular ageing in pooled population-based cohort studies: The global metabolic syndrome and artery research consortium

Metabolic syndrome, Arteries REsearch (MARE) Consortium, 2018, In : Journal of hypertension. 36, 12, p. 2340-2349 10 p.

Research output: Contribution to journalArticle

2019
Open Access
2018

TGFβ1 reinforces arterial aging in the vascular smooth muscle cell through a long-range regulation of the cytoskeletal stiffness

Zhu, W., Kim, B. C., Wang, M., Huang, J., Isak, A., Bexiga, N. M., Monticone, R., Ha, T., Lakatta, E. G. & An, S. S., Dec 1 2018, In : Scientific reports. 8, 1, 2668.

Research output: Contribution to journalArticle

2020

Disulfiram Treatment Normalizes Body Weight in Obese Mice

Bernier, M., Mitchell, S. J., Wahl, D., Diaz, A., Singh, A., Seo, W., Wang, M., Ali, A., Kaiser, T., Price, N. L., Aon, M. A., Kim, E. Y., Petr, M. A., Cai, H., Warren, A., Di Germanio, C., Di Francesco, A., Fishbein, K., Guiterrez, V., Harney, D. & 19 others, Koay, Y. C., Mach, J., Enamorado, I. N., Pulpitel, T., Wang, Y., Zhang, J., Zhang, L., Spencer, R. G., Becker, K. G., Egan, J. M., Lakatta, E. G., O'Sullivan, J., Larance, M., LeCouteur, D. G., Cogger, V. C., Gao, B., Fernandez-Hernando, C., Cuervo, A. M. & de Cabo, R., Aug 4 2020, In : Cell Metabolism. 32, 2, p. 203-214.e4

Research output: Contribution to journalArticle

Open Access
2018

Antibody to marinobufagenin reverses placenta-induced fibrosis of umbilical arteries in preeclampsia

Fedorova, O. V., Ishkaraeva, V. V., Grigorova, Y. N., Reznik, V. A., Kolodkin, N. I., Zazerskaya, I. E., Zernetkina, V., Agalakova, N. I., Tapilskaya, N. I., Adair, C. D., Lakatta, E. & Bagrov, A. Y., Aug 13 2018, In : International Journal of Molecular Sciences. 19, 8, 2377.

Research output: Contribution to journalArticle

2017

Mammalian γ2 AMPK regulates intrinsic heart rate

Yavari, A., Bellahcene, M., Bucchi, A., Sirenko, S., Pinter, K., Herring, N., Jung, J. J., Tarasov, K. V., Sharpe, E. J., Wolfien, M., Czibik, G., Steeples, V., Ghaffari, S., Nguyen, C., Stockenhuber, A., Clair, J. R. S., Rimmbach, C., Okamoto, Y., Yang, D., Wang, M. & 44 others, Ziman, B. D., Moen, J. M., Riordon, D. R., Ramirez, C., Paina, M., Lee, J., Zhang, J., Ahmet, I., Matt, M. G., Tarasova, Y. S., Baban, DI., Sahgal, N., Lockstone, H., Puliyadi, R., De Bono, J., Siggs, O. M., Gomes, J., Muskett, H., Maguire, M. L., Beglov, Y., Kelly, M., Dos Santos, P. P. N., Bright, N. J., Woods, A., Gehmlich, K., Isackson, H., Douglas, G., Ferguson, D. J. P., Schneider, J. E., Tinker, A., Wolkenhauer, O., Channon, K. M., Cornall, R. J., Sternick, E. B., Paterson, D. J., Redwood, C. S., Carling, D., Proenza, C., David, R., Baruscotti, M., DIfrancesco, D., Lakatta, E. G., Watkins, H. & Ashrafian, H., Dec 1 2017, In : Nature communications. 8, 1, 1258.

Research output: Contribution to journalArticle

The Systematic Evaluation of Identifying the Infarct Related Artery Utilizing Cardiac Magnetic Resonance in Patients Presenting with ST-Elevation Myocardial Infarction

Hamo, C. E., Klem, I., Rao, S. V., Songco, V., Najjar, S., Lakatta, E. G., Raman, S. V., Harrington, R. A. & Heitner, J. F., Jan 2017, In : PloS one. 12, 1, e0169108.

Research output: Contribution to journalArticle

2020

Increased Drp1 acetylation by lipid overload induces cardiomyocyte death and heart dysfunction

Hu, Q., Zhang, H., Cortés, N. G., Wu, D., Wang, P., Zhang, J., Mattison, J. A., Smith, E., Bettcher, L. F., Wang, M., Lakatta, E. G., Sheu, S. S. & Wang, W., Feb 14 2020, In : Circulation research. p. 456-470 15 p.

Research output: Contribution to journalArticle

2019

To help aging populations, classify organismal senescence

Calimport, S. R. G., Bentley, B. L., Stewart, C. E., Pawelec, G., Scuteri, A., Vinciguerra, M., Slack, C., Chen, D., Harries, L. W., Marchant, G., Alexander Fleming, G., Conboy, M., Antebi, A., Small, G. W., Gil, J., Lakatta, E. G., Richardson, A., Rosen, C., Nikolich, K., Wyss-Coray, T. & 5 others, Steinman, L., Montine, T., de Magalhães, J. P., Campisi, J. & Church, G., Nov 1 2019, In : Science. 366, 6465, p. 576-578 3 p.

Research output: Contribution to journalArticle

Monoclonal Antibody to Marinobufagenin Downregulates TGFβ Profibrotic Signaling in Left Ventricle and Kidney and Reduces Tissue Remodeling in Salt-Sensitive Hypertension

Zhang, Y., Wei, W., Shilova, V., Petrashevskaya, N. N., Zernetkina, V. I., Grigorova, Y. N., Marshall, C. A., Fenner, R. C., Lehrmann, E., Wood, W. H., Becker, K. G., Lakatta, E. G., Bagrov, A. Y. & Fedorova, O. V., Oct 15 2019, In : Journal of the American Heart Association. 8, 20, p. e012138

Research output: Contribution to journalArticle

Open Access

Discoidin domain Receptor 2: A determinant of metabolic syndrome-associated arterial fibrosis in non-human primates

Ushakumary, M. G., Wang, M., Harikrishnan, V., Titus, A. S., Zhang, J., Liu, L., Monticone, R., Wang, Y., Mattison, J. A., De Cabo, R., Lakatta, E. G. & Kailasam, S., Dec 1 2019, In : PloS one. 14, 12, e0225911.

Research output: Contribution to journalArticle

Open Access
2018

Positive Feedback Mechanisms among Local Ca Releases, NCX, and ICaL Ignite Pacemaker Action Potentials

Lyashkov, A. E., Beahr, J., Lakatta, E., Yaniv, Y. & Maltsev, V. A., Mar 13 2018, In : Biophysical Journal. 114, 5, p. 1176-1189 14 p.

Research output: Contribution to journalArticle

Dietary sodium restriction reduces arterial stiffness, vascular TGF-β-dependent fibrosis and marinobufagenin in young normotensive rats

Grigorova, Y. N., Wei, W., Petrashevskaya, N., Zernetkina, V., Juhasz, O., Fenner, R., Gilbert, C., Lakatta, E. G., Shapiro, J. I., Bagrov, A. Y. & Fedorova, O. V., Oct 15 2018, In : International journal of molecular sciences. 19, 10, 3168.

Research output: Contribution to journalArticle

2017

Prognostic utility of morning blood pressure surge for 20-year all- cause and cardiovascular mortalities: Results of a community-based study

Cheng, H. M., Wu, C. L., Sung, S. H., Lee, J. C., Kario, K., Chiang, C. E., Huang, C. J., Hsu, P. F., Chuang, S. Y., Lakatta, E. G., Yin, F. C. P., Chou, P. & Chen, C. H., Dec 1 2017, In : Journal of the American Heart Association. 6, 12, e007667.

Research output: Contribution to journalArticle

2020

Impact of Stiffer Arteries on the Response to Antihypertensive Treatment: A Longitudinal Study of the SardiNIA Cohort

Lakatta, E. G., AlunniFegatelli, D., Morrell, C. H., Fiorillo, E., Orru, M., Delitala, A., Marongiu, M., Schlessinger, D., Cucca, F. & Scuteri, A., Jun 2020, In : Journal of the American Medical Directors Association. 21, 6, p. 720-725 6 p.

Research output: Contribution to journalArticle

2018

Adipocytokine correlations with thyroid function and autoimmunity in euthyroid sardinians

Delitala, A. P., Steri, M., Fiorillo, E., Marongiu, M., Lakatta, E., Schlessinger, D. & Cucca, F., Nov 1 2018, In : Cytokine. 111, p. 189-193 5 p.

Research output: Contribution to journalArticle

2017

Spontaneous, local diastolic subsarcolemmal calcium releases in single, isolated guinea-pig sinoatrial nodal cells

Sirenko, S. G., Yang, D., Maltseva, L. A., Kim, M. S., Lakatta, E. G. & Maltsev, V. A., Sep 2017, In : PloS one. 12, 9, e0185222.

Research output: Contribution to journalArticle

Lower mitochondrial energy production of the thigh muscles in patients with low-normal ankle-brachial index

AlGhatrif, M., Zane, A., Oberdier, M., Canepa, M., Studenski, S., Simonsick, E., Spencer, R. G., Fishbein, K., Reiter, D., Lakatta, E. G., McDermott, M. M. & Ferrucci, L., Sep 1 2017, In : Journal of the American Heart Association. 6, 9, e006604.

Research output: Contribution to journalArticle

2018

Heterogeneity of calcium clock functions in dormant, dysrhythmically and rhythmically firing single pacemaker cells isolated from SA node

Kim, M. S., Maltsev, A. V., Monfredi, O., Maltseva, L. A., Wirth, A., Florio, M. C., Tsutsui, K., Riordon, D. R., Parsons, S. P., Tagirova, S., Ziman, B. D., Stern, M. D., Lakatta, E. & Maltsev, V. A., Sep 1 2018, In : Cell Calcium. 74, p. 168-179 12 p.

Research output: Contribution to journalArticle

Aldosterone, inactive matrix gla-protein, and large artery stiffness in hypertension

Chirinos, J. A., Sardana, M., Syed, A. A., Koppula, M. R., Varakantam, S., Vasim, I., Oldland, H. G., Phan, T. S., Drummen, N. E. A., Vermeer, C., Townsend, R. R., Akers, S. R., Wei, W., Lakatta, E. G. & Fedorova, O. V., Sep 2018, In : Journal of the American Society of Hypertension. 12, 9, p. 681-689 9 p.

Research output: Contribution to journalArticle

2019

Overexpression of a neuronal type adenylyl cyclase (type 8) in sinoatrial node markedly impacts heart rate and rhythm

Moen, J. M., Matt, M. G., Ramirez, C., Tarasov, K. V., Chakir, K., Tarasova, Y. S., Lukyanenko, Y., Tsutsui, K., Monfredi, O., Morrell, C. H., Tagirova, S., Yaniv, Y., Huynh, T., Pacak, K., Ahmet, I. & Lakatta, E. G., 2019, In : Frontiers in Neuroscience. 13, JUN, 615.

Research output: Contribution to journalArticle

Open Access

Complexities in cardiovascular rhythmicity: Perspectives on circadian normality, ageing and disease

Monfredi, O. & Lakatta, E. G., Sep 1 2019, In : Cardiovascular research. 115, 11, p. 1576-1595 20 p.

Research output: Contribution to journalArticle

Open Access
2018