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  • Ralph H Hruban
2017

The many faces of pancreatic serous cystadenoma: Radiologic and pathologic correlation

Chu, L. C. H., Singhi, A. D., Haroun, R. R., Hruban, R. H. & Fishman, E. K., Mar 1 2017, In : Diagnostic and interventional imaging. 98, 3, p. 191-202 12 p.

Research output: Contribution to journalArticle

2018

Incidentally detected pancreatic neuroendocrine microadenoma with lymph node metastasis

Kwon, J. H., Kim, H. J., Park, D. H., Lee, Y. J., Heaphy, C. M., Klöppel, G., Hruban, R. H. & Hong, S. M., Jul 12 2018, (Accepted/In press) In : Virchows Archiv. p. 1-5 5 p.

Research output: Contribution to journalArticle

Pancreatic neuroendocrine tumor: review of heterogeneous spectrum of CT appearance

Lee, N. J., Hruban, R. H. & Fishman, E. K., Mar 28 2018, (Accepted/In press) In : Abdominal Radiology. p. 1-10 10 p.

Research output: Contribution to journalArticle

Are pancreatic IPMN volumes measured on MRI images more reproducible than diameters? An assessment in a large single-institution cohort

Pandey, P., Pandey, A., Varzaneh, F. N., Ghasabeh, M. A., Fouladi, D., Khoshpouri, P., Shao, N., Zarghampour, M., Hruban, R. H., Canto, M., O'Broin-Lennon, A. M. & Kamel, I. R., Feb 5 2018, (Accepted/In press) In : European Radiology. p. 1-11 11 p.

Research output: Contribution to journalArticle

2019

Screening for Pancreatic Cancer Gets a D, but the Student Is Improving

Hruban, R. H. & Lillemoe, K. D., Sep 2019, In : JAMA surgery. 154, 9, p. 795-797 3 p.

Research output: Contribution to journalEditorial

2017

A p53 Super-tumor Suppressor Reveals a Tumor Suppressive p53-Ptpn14-Yap Axis in Pancreatic Cancer

Mello, S. S., Valente, L. J., Raj, N., Seoane, J. A., Flowers, B. M., McClendon, J., Bieging-Rolett, K. T., Lee, J., Ivanochko, D., Kozak, M. M., Chang, D. T., Longacre, T. A., Koong, A. C., Arrowsmith, C. H., Kim, S. K., Vogel, H., Wood, L. D., Hruban, R. H., Curtis, C. & Attardi, L. D., Oct 9 2017, In : Cancer cell. 32, 4, p. 460-473.e6

Research output: Contribution to journalArticle

2018

The molecular biology of Pancreas cancer

Kern, S. E. & Hruban, R. H., Nov 16 2018, DeVita, Hellman, and Rosenberg's Cancer: Principles & Practice of Oncology. Wolters Kluwer Health Pharma Solutions (Europe) Ltd, p. 797-803 7 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2019

Added value of apparent diffusion coefficient in distinguishing between serous and mucin-producing pancreatic cystic neoplasms

Pandey, P., Pandey, A., Shao, N., Varzaneh, F. N., Ghasabeh, M. A., Zharghampour, M., Khoshpouri, P., Fouladi, D., Eng, J., O'Broin-Lennon, A. M., Canto, M., Hruban, R. H. & Kamel, I. R., Jan 1 2019, In : European Radiology.

Research output: Contribution to journalArticle

2017
2019
Open Access
2018

A "clearer" View of Pancreatic Pathology: A Review of Tissue Clearing and Advanced Microscopy Techniques

Hong, S. M., Noë, M., Hruban, C. A., Thompson, E., Wood, L. D. & Hruban, R. H., Jan 1 2018, (Accepted/In press) In : Advances in Anatomic Pathology.

Research output: Contribution to journalArticle

2019

Survival in Locally Advanced Pancreatic Cancer after Neoadjuvant Therapy and Surgical Resection

Gemenetzis, G., Groot, V. P., Blair, A. B., Laheru, D. A., Zheng, L., Narang, A. K., Fishman, E. K., Hruban, R. H., Yu, J., Burkhart, R. A., Cameron, J. L., Weiss, M. J., Wolfgang, C. L. & He, J., Aug 1 2019, In : Annals of surgery. 270, 2, p. 340-347 8 p.

Research output: Contribution to journalArticle

2018

Long-term analysis of 2 prospective studies that incorporate mitomycin C into an adjuvant chemoradiation regimen for pancreatic and periampullary cancers

Schunke, K. J., Rosati, L. M., Zahurak, M., Herman, J., Narang, A. K., Usach, I., Klein, A. P., Yeo, C. J., Korman, L. T., Hruban, R. H., Cameron, J. L., Laheru, D. A. & Abrams, R. A., Jan 1 2018, (Accepted/In press) In : Advances in Radiation Oncology.

Research output: Contribution to journalArticle

2016

Surgical and molecular pathology of pancreatic neoplasms

Hackeng, W. M., Hruban, R. H., Offerhaus, G. J. A. & Brosens, L. A. A., Jun 7 2016, In : Diagnostic Pathology. 11, 1, 47.

Research output: Contribution to journalReview article

2020

Recurrent Rearrangements in PRKACA and PRKACB in Intraductal Oncocytic Papillary Neoplasms of the Pancreas and Bile Duct

Singhi, A. D., Wood, L. D., Parks, E., Torbenson, M. S., Felsenstein, M., Hruban, R. H., Nikiforova, M. N., Wald, A. I., Kaya, C., Nikiforov, Y. E., Favazza, L., He, J., McGrath, K., Fasanella, K. E., Brand, R. E., Lennon, A. M., Furlan, A., Dasyam, A. K., Zureikat, A. H., Zeh, H. J. & 3 others, Lee, K., Bartlett, D. L. & Slivka, A., Feb 2020, In : Gastroenterology. 158, 3, p. 573-582.e2

Research output: Contribution to journalArticle

Open Access
2018

Genome-Wide Somatic Copy Number Alterations and Mutations in High-Grade Pancreatic Intraepithelial Neoplasia

Hata, T., Suenaga, M., Marchionni, L., Macgregor-Das, A., Yu, J., Shindo, K., Tamura, K., Hruban, R. H. & Goggins, M., Jul 2018, In : American Journal of Pathology. 188, 7, p. 1723-1733 11 p.

Research output: Contribution to journalArticle

2019

Surveillance for pancreatic cancer in high-risk individuals

International CAncer of the Pancreas Screening (CAPS) Consortium, Oct 1 2019, In : BJS open. 3, 5, p. 656-665 10 p.

Research output: Contribution to journalArticle

Open Access
2016

Digital next-generation sequencing identifies low-abundance mutations in pancreatic juice samples collected from the duodenum of patients with pancreatic cancer and intraductal papillary mucinous neoplasms

Yu, J., Sadakari, Y., Shindo, K., Suenaga, M., Brant, A., Almario, J. A. N., Borges, M., Barkley, T., Fesharakizadeh, S., Ford, M., Hruban, R. H., Shin, E., O'Broin-Lennon, A. M., Canto, M. & Goggins, M. S., Jul 18 2016, (Accepted/In press) In : Gut.

Research output: Contribution to journalArticle

2020

Surgical Outcomes After Pancreatic Resection of Screening-Detected Lesions in Individuals at High Risk for Developing Pancreatic Cancer

Canto, M. I., Kerdsirichairat, T., Yeo, C. J., Hruban, R. H., Shin, E. J., Almario, J. A., Blackford, A., Ford, M., Klein, A. P., Javed, A. A., Lennon, A. M., Zaheer, A., Kamel, I. R., Fishman, E. K., Burkhart, R., He, J., Makary, M., Weiss, M. J., Schulick, R. D., Goggins, M. G. & 1 others, Wolfgang, C. L., May 1 2020, In : Journal of Gastrointestinal Surgery. 24, 5, p. 1101-1110 10 p.

Research output: Contribution to journalArticle

Annotated normal CT data of the abdomen for deep learning: Challenges and strategies for implementation

Park, S., Chu, L. C., Fishman, E. K., Yuille, A. L., Vogelstein, B., Kinzler, K. W., Horton, K. M., Hruban, R. H., Zinreich, E. S., Fadaei Fouladi, D., Shayesteh, S., Graves, J. & Kawamoto, S., Jan 2020, In : Diagnostic and Interventional Imaging. 101, 1, p. 35-44 10 p.

Research output: Contribution to journalArticle

2016

Neutrophil-to-lymphocyte Ratio is a Predictive Marker for Invasive Malignancy in Intraductal Papillary Mucinous Neoplasms of the Pancreas

Gemenetzis, G., Bagante, F., Griffin, J. F., Rezaee, N., Javed, A. A., Manos, L. L., O'Broin-Lennon, A. M., Wood, L. D., Hruban, R. H., Zheng, L., Zaheer, A., Fishman, E. K., Ahuja, N., Cameron, J. L., Weiss, M. J., He, J. & Wolfgang, C., Sep 14 2016, (Accepted/In press) In : Annals of Surgery.

Research output: Contribution to journalArticle

Targeted DNA Sequencing Reveals Patterns of Local Progression in the Pancreatic Remnant Following Resection of Intraductal Papillary Mucinous Neoplasm (IPMN) of the Pancreas

Pea, A., Yu, J., Rezaee, N., Luchini, C., He, J., Dal Molin, M., Griffin, J. F., Fedor, H., Fesharakizadeh, S., Salvia, R., Weiss, M. J., Bassi, C., Cameron, J. L., Zheng, L., Scarpa, A., Hruban, R. H., O'Broin-Lennon, A. M., Goggins, M. S., Wolfgang, C. & Wood, L. D., Jul 18 2016, (Accepted/In press) In : Annals of Surgery.

Research output: Contribution to journalArticle

2017

A novel approach for selecting combination clinical markers of pathology applied to a large retrospective cohort of surgically resected pancreatic cysts

Masica, D. L., Molin, M. D., Wolfgang, C. L., Tomita, T., Ostovaneh, M. R., Blackford, A., Moran, R. A., Law, J. K., Barkley, T., Goggins, M., Canto, M. I., Pittman, M., Eshleman, J. R., Ali, S. Z., Fishman, E. K., Kamel, I. R., Raman, S. P., Zaheer, A., Ahuja, N., Makary, M. A. & 16 others, Weiss, M. J., Hirose, K., Cameron, J. L., Rezaee, N., He, J., Ahn, Y. J., Wu, W., Wang, Y., Springer, S., Diaz, L. L., Papadopoulos, N., Hruban, R. H., Kinzler, K. W., Vogelstein, B., Karchin, R. & Lennon, A. M., 2017, In : Journal of the American Medical Informatics Association. 24, 1, p. 145-152 8 p.

Research output: Contribution to journalArticle

2018

Lessons learned from 29 lymphoepithelial cysts of the pancreas: Institutional experience and review of the literature

Groot, V. P., Thakker, S. S., Gemenetzis, G., Noë, M., Javed, A. A., Burkhart, R., Noveiry, B. B., Cameron, J. L., Weiss, M. J., VandenBussche, C., Fishman, E. K., Hruban, R. H., Wolfgang, C., O'Broin-Lennon, A. M. & He, J., Jan 1 2018, (Accepted/In press) In : HPB.

Research output: Contribution to journalArticle

Implications of the Pattern of Disease Recurrence on Survival Following Pancreatectomy for Pancreatic Ductal Adenocarcinoma

Groot, V. P., Gemenetzis, G., Blair, A. B., Ding, D., Javed, A. A., Burkhart, R., Yu, J., Borel Rinkes, I. H., Molenaar, I. Q., Cameron, J. L., Fishman, E. K., Hruban, R. H., Weiss, M. J., Wolfgang, C. & He, J., Jun 14 2018, (Accepted/In press) In : Annals of Surgical Oncology. p. 1-9 9 p.

Research output: Contribution to journalArticle

2016

Reliable detection of somatic mutations in fine needle aspirates of pancreatic cancer with next-generation sequencing: Implications for surgical management

Valero, V., Saunders, T. J., He, J., Weiss, M. J., Cameron, J. L., Dholakia, A., Wild, A. T., Shin, E. J., Khashab, M. A., O'Broin-Lennon, A. M., Ali, S. Z., Laheru, D., Hruban, R. H., Iacobuzio-Donahue, C., Herman, J. & Wolfgang, C. L., Jan 1 2016, In : Annals of surgery. 263, 1, p. 153-161 9 p.

Research output: Contribution to journalArticle

Circulating tumor cell phenotype predicts recurrence and survival in pancreatic adenocarcinoma

Poruk, K. E., Valero, V., Saunders, T., Blackford, A. L., Griffin, J. F., Poling, J., Hruban, R. H., Anders, R. A., Herman, J., Zheng, L., Rasheed, Z. A., Laheru, D. A., Ahuja, N., Weiss, M. J., Cameron, J. L., Goggins, M., Iacobuzio-Donahue, C. A., Wood, L. D. & Wolfgang, C. L., Nov 28 2016, In : Annals of surgery. 264, 6, p. 1073-1081 9 p.

Research output: Contribution to journalArticle

2020

Genetic Analysis of Small Well-differentiated Pancreatic Neuroendocrine Tumors Identifies Subgroups with Differing Risks of Liver Metastases

Pea, A., Yu, J., Marchionni, L., Noe, M., Luchini, C., Pulvirenti, A., De Wilde, R. F., Brosens, L. A., Rezaee, N., Javed, A., Chianchiano, P., Gobbo, S., Regi, P., Salvia, R., Bassi, C., He, J., Weiss, M. J., Cameron, J. L., Offerhaus, G. J. A., Hruban, R. H. & 5 others, Lawlor, R. T., Scarpa, A., Heaphy, C. M., Wood, L. D. & Wolfgang, C. L., Mar 1 2020, In : Annals of surgery. 271, 3, p. 566-573 8 p.

Research output: Contribution to journalArticle

2018

Is a Pathological Complete Response Following Neoadjuvant Chemoradiation Associated with Prolonged Survival in Patients with Pancreatic Cancer?

He, J., Blair, A. B., Groot, V. P., Javed, A. A., Burkhart, R. A., Gemenetzis, G., Hruban, R. H., Waters, K. M., Poling, J., Zheng, L., Laheru, D., Herman, J., Makary, M. A., Weiss, M. J., Cameron, J. L. & Wolfgang, C. L., Jul 1 2018, In : Annals of Surgery. 268, 1, p. 1-8 8 p.

Research output: Contribution to journalArticle

2019
2017

Lost in translation: Returning germline genetic results in genome-scale cancer research

Australian Pancreatic Cancer Genome Initiative, Apr 28 2017, In : Genome Medicine. 9, 1, 41.

Research output: Contribution to journalArticle

Integrated Genomic Characterization of Pancreatic Ductal Adenocarcinoma

Raphael, B. J., Hruban, R. H., Aguirre, A. J., Moffitt, R. A., Yeh, J. J., Stewart, C., Robertson, A. G., Cherniack, A. D., Gupta, M., Getz, G., Gabriel, S. B., Meyerson, M., Cibulskis, C., Fei, S. S., Hinoue, T., Shen, H., Laird, P. W., Ling, S., Lu, Y., Mills, G. B. & 251 others, Akbani, R., Loher, P., Londin, E. R., Rigoutsos, I., Telonis, A. G., Gibb, E. A., Goldenberg, A., Mezlini, A. M., Hoadley, K. A., Collisson, E., Lander, E., Murray, B. A., Hess, J., Rosenberg, M., Bergelson, L., Zhang, H., Cho, J., Tiao, G., Kim, J., Livitz, D., Leshchiner, I., Reardon, B., Van Allen, E., Kamburov, A., Beroukhim, R., Saksena, G., Schumacher, S. E., Noble, M. S., Heiman, D. I., Gehlenborg, N., Kim, J., Lawrence, M. S., Adsay, V., Petersen, G., Klimstra, D., Bardeesy, N., Leiserson, M. D. M., Bowlby, R., Kasaian, K., Birol, I., Mungall, K. L., Sadeghi, S., Weinstein, J. N., Spellman, P. T., Liu, Y., Amundadottir, L. T., Tepper, J., Singhi, A. D., Dhir, R., Paul, D., Smyrk, T., Zhang, L., Kim, P., Bowen, J., Frick, J., Gastier-Foster, J. M., Gerken, M., Lau, K., Leraas, K. M., Lichtenberg, T. M., Ramirez, N. C., Renkel, J., Sherman, M., Wise, L., Yena, P., Zmuda, E., Shih, J., Ally, A., Balasundaram, M., Carlsen, R., Chu, A., Chuah, E., Clarke, A., Dhalla, N., Holt, R. A., Jones, S. J. M., Lee, D., Ma, Y., Marra, M. A., Mayo, M., Moore, R. A., Mungall, A. J., Schein, J. E., Sipahimalani, P., Tam, A., Thiessen, N., Tse, K., Wong, T., Brooks, D., Auman, J. T., Balu, S., Bodenheimer, T., Hayes, D. N., Hoyle, A. P., Jefferys, S. R., Jones, C. D., Meng, S., Mieczkowski, P. A., Mose, L. E., Perou, C. M., Perou, A. H., Roach, J., Shi, Y., Simons, J. V., Skelly, T., Soloway, M. G., Tan, D., Veluvolu, U., Parker, J. S., Wilkerson, M. D., Korkut, A., Senbabaoglu, Y., Burch, P., McWilliams, R., Chaffee, K., Oberg, A., Zhang, W., Gingras, M. C., Wheeler, D. A., Xi, L., Albert, M., Bartlett, J., Sekhon, H., Stephen, Y., Howard, Z., Judy, M., Breggia, A., Shroff, R. T., Chudamani, S., Liu, J., Lolla, L., Naresh, R., Pihl, T., Sun, Q., Wan, Y., Wu, Y., Jennifer, S., Roggin, K., Becker, K. F., Behera, M., Bennett, J., Boice, L., Burks, E., Carlotti Junior, C. G., Chabot, J., Pretti da Cunha Tirapelli, D., Sebastião dos Santos, J., Dubina, M., Eschbacher, J., Huang, M., Huelsenbeck-Dill, L., Jenkins, R., Karpov, A., Kemp, R., Lyadov, V., Maithel, S., Manikhas, G., Montgomery, E., Noushmehr, H., Osunkoya, A., Owonikoko, T., Paklina, O., Potapova, O., Ramalingam, S., Rathmell, W. K., Rieger-Christ, K., Saller, C., Setdikova, G., Shabunin, A., Sica, G., Su, T., Sullivan, T., Swanson, P., Tarvin, K., Tavobilov, M., Thorne, L. B., Urbanski, S., Voronina, O., Wang, T., Crain, D., Curley, E., Gardner, J., Mallery, D., Morris, S., Paulauskis, J., Penny, R., Shelton, C., Shelton, T., Janssen, K. P., Bathe, O., Bahary, N., Slotta-Huspenina, J., Johns, A., Hibshoosh, H., Hwang, R. F., Sepulveda, A., Radenbaugh, A., Baylin, S. B., Berrios, M., Bootwalla, M. S., Holbrook, A., Lai, P. H., Maglinte, D. T., Mahurkar, S., Triche, T. J., Van Den Berg, D. J., Weisenberger, D. J., Chin, L., Kucherlapati, R., Kucherlapati, M., Pantazi, A., Park, P., Saksena, G., Voet, D., Lin, P., Frazer, S., Defreitas, T., Meier, S., Chin, L., Kwon, S. Y., Kim, Y. H., Park, S. J., Han, S. S., Kim, S. H., Kim, H., Furth, E., Tempero, M., Sander, C., Biankin, A., Chang, D., Bailey, P., Gill, A., Kench, J., Grimmond, S., Johns, A., Cancer Genome Initiative (APGI, A. P., Postier, R., Zuna, R., Sicotte, H., Demchok, J. A., Ferguson, M. L., Hutter, C. M., Mills Shaw, K. R., Sheth, M., Sofia, H. J., Tarnuzzer, R., Wang, Z., Yang, L., Zhang, J. J., Felau, I. & Zenklusen, J. C., Aug 14 2017, In : Cancer cell. 32, 2, p. 185-203.e13

Research output: Contribution to journalArticle

2018

The evolution of earned, transparent, and quantifiable faculty salary compensation: The Johns Hopkins pathology experience

Burns, K. H., Borowitz, M. J., Carroll, K. C., Gocke, C. D., Hooper, J. E., Amukele, T., Tobian, A. A. R., Valentine, A., Kahl, R., Rodas-Eral, V., Boitnott, J. K., Jackson, J. B., Sanfilippo, F. & Hruban, R. H., Jan 1 2018, In : Academic Pathology. 5

Research output: Contribution to journalArticle

2020

Pancreatic Nerve Sheath Tumors: a Single Institutional Series and Systematic Review of the Literature

Javed, A. A., Wright, M. J., Hasanain, A., Chang, K., Burkhart, R. A., Hruban, R. H., Thompson, E., Fishman, E. K., Cameron, J. L., He, J., Wolfgang, C. L. & Weiss, M. J., Apr 1 2020, In : Journal of Gastrointestinal Surgery. 24, 4, p. 841-848 8 p.

Research output: Contribution to journalArticle

2019

The glycan CA19-9 promotes pancreatitis and pancreatic cancer in mice

Engle, D. D., Tiriac, H., Rivera, K. D., Pommier, A., Whalen, S., Oni, T. E., Alagesan, B., Lee, E. J., Yao, M. A., Lucito, M. S., Spielman, B., Silva, B. D., Schoepfer, C., Wright, K., Creighton, B., Afinowicz, L., Yu, K. H., Grützmann, R., Aust, D., Gimotty, P. A. & 8 others, Pollard, K. S., Hruban, R. H., Goggins, M. G., Pilarsky, C., Park, Y., Pappin, D. J., Hollingsworth, M. A. & Tuveson, D. A., Jan 1 2019, In : Science. 364, 6446, p. 1156-1162 7 p.

Research output: Contribution to journalArticle

2017

Genetic analyses of isolated high-grade pancreatic intraepithelial neoplasia (HG-PanIN) reveal paucity of alterations in TP53 and SMAD4

Hosoda, W., Chianchiano, P., Griffin, J. F., Pittman, M. E., Brosens, L. A. A., Noë, M., Yu, J., Shindo, K., Suenaga, M., Rezaee, N., Yonescu, R., Ning, Y., Albores-Saavedra, J., Yoshizawa, N., Harada, K., Yoshizawa, A., Hanada, K., Yonehara, S., Shimizu, M., Uehara, T. & 6 others, Samra, J. S., Gill, A. J., Wolfgang, C. L., Goggins, M. G., Hruban, R. H. & Wood, L. D., May 2017, In : Journal of Pathology. 242, 1, p. 16-23 8 p.

Research output: Contribution to journalArticle

2016

Pancreatic Cancer Chemoprevention Translational Workshop: Meeting Report

Miller, M. S., Allen, P., Brentnall, T. A., Goggins, M., Hruban, R. H., Petersen, G. M., Rao, C. V., Whitcomb, D. C., Brand, R. E., Chari, S. T., Klein, A. P., Lubman, D. M., Rhim, A. D., Simeone, D. M., Wolpin, B. M., Umar, A., Srivastava, S., Steele, V. E. & Rinaudo, J. A. S., Sep 1 2016, In : Pancreas. 45, 8, p. 1080-1091 12 p.

Research output: Contribution to journalArticle

Erratum: Intraductal tubulopapillary neoplasms of the bile ducts: Clinicopathologic, immunohistochemical, and molecular analysis of 20 cases (Modern Pathology (2016) 29 (93))

Schlitter, A. M., Jang, K. T., Klöppel, G., Saka, B., Hong, S. M., Choi, H., Offerhaus, G. J., Hruban, R. H., Zen, Y., Konukiewitz, B., Regel, I., Allgäuer, M., Balci, S., Basturk, O., Reid, M. D., Esposito, I. & Adsay, V., Jan 1 2016, In : Modern Pathology. 29, 1, 1 p.

Research output: Contribution to journalComment/debate

2020

Intraductal pancreatic cancer is less responsive than cancer in the stroma to neoadjuvant chemotherapy

Fujikura, K., Hutchings, D., Braxton, A. M., Zhu, Q., Laheru, D. A., Hruban, R. H., Thompson, E. D. & Wood, L. D., Jan 1 2020, (Accepted/In press) In : Modern Pathology.

Research output: Contribution to journalArticle

2019

Biphenotypic Differentiation of Pancreatic Cancer in 3-Dimensional Culture

Matsushita, Y., Smith, B., Delannoy, M., Trujillo, M. A., Chianchiano, P., McMillan, R., Kamiyama, H., Liang, H., Thompson, E. D., Hruban, R. H., Matsui, W., Wood, L. D., Roberts, N. J. & Eshleman, J. R., Oct 1 2019, In : Pancreas. 48, 9, p. 1225-1231 7 p.

Research output: Contribution to journalArticle

2016
2019

Is the Early Detection of Pancreatic Cancer Possible? It Is Good News, Bad News

Hruban, R. H., May 1 2019, In : Pancreas. 48, 5, p. 591-593 3 p.

Research output: Contribution to journalEditorial

2020

Cell fitness screens reveal a conflict between LINE-1 retrotransposition and DNA replication

Ardeljan, D., Steranka, J. P., Liu, C., Li, Z., Taylor, M. S., Payer, L. M., Gorbounov, M., Sarnecki, J. S., Deshpande, V., Hruban, R. H., Boeke, J. D., Fenyö, D., Wu, P. H., Smogorzewska, A., Holland, A. J. & Burns, K. H., Feb 1 2020, In : Nature Structural and Molecular Biology. 27, 2, p. 168-178 11 p.

Research output: Contribution to journalArticle

2018

Mutations in the pancreatic secretory enzymes CPA1 and CPB1 are associated with pancreatic cancer

Tamura, K., Yu, J., Hata, T., Suenaga, M., Shindo, K., Abe, T., MacGregor-Das, A., Borges, M., Wolfgang, C. L., Weiss, M. J., He, J., Canto, M. I., Petersen, G. M., Gallinger, S., Syngal, S., Brand, R. E., Rustgi, A., Olson, S. H., Stoffel, E., Cote, M. L. & 13 others, Zogopoulos, G., Potash, J. B., Goes, F. S., McCombie, R. W., Zandi, P. P., Pirooznia, M., Kramer, M., Parla, J., Eshleman, J. R., Roberts, N. J., Hruban, R. H., Klein, A. P. & Goggins, M., May 1 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 18, p. 4767-4772 6 p.

Research output: Contribution to journalArticle

2020

Detection of Circulating Tumor DNA in Patients with Pancreatic Cancer Using Digital Next-Generation Sequencing

Macgregor-Das, A., Yu, J., Tamura, K., Abe, T., Suenaga, M., Shindo, K., Borges, M., Koi, C., Kohi, S., Sadakari, Y., Dal Molin, M., Almario, J. A., Ford, M., Chuidian, M., Burkhart, R., He, J., Hruban, R. H., Eshleman, J. R., Klein, A. P., Wolfgang, C. L. & 2 others, Canto, M. I. & Goggins, M., Jun 2020, In : Journal of Molecular Diagnostics. 22, 6, p. 748-756 9 p.

Research output: Contribution to journalArticle

Pancreatic acinar cell carcinomas and mixed acinar-neuroendocrine carcinomas are more clinically aggressive than grade 1 pancreatic neuroendocrine tumours

Kim, J. Y., Brosnan-Cashman, J. A., Kim, J., An, S., Lee, K. B., Kim, H., Park, D. Y., Jang, K. T., Oh, Y. H., Hruban, R. H., Heaphy, C. M. & Hong, S. M., Apr 2020, In : Pathology. 52, 3, p. 336-347 12 p.

Research output: Contribution to journalArticle

Three-dimensional analysis of extrahepatic cholangiocarcinoma and tumor budding

Yoshizawa, T., Hong, S. M., Jung, D. J., Noë, M., Kiemen, A., Wu, P. H., Wirtz, D., Hruban, R. H., Wood, L. D. & Oshima, K., Aug 1 2020, In : Journal of Pathology. 251, 4, p. 400-410 11 p.

Research output: Contribution to journalArticle

Assessing aneuploidy with repetitive element sequencing

Douville, C., Cohen, J. D., Ptak, J., Popoli, M., Schaefer, J., Silliman, N., Dobbyn, L., Schoen, R. E., Tie, J., Gibbs, P., Goggins, M., Wolfgang, C. L., Wang, T. L., Shih, I. M., Karchin, R., Lennon, A. M., Hruban, R. H., Tomasetti, C., Bettegowda, C., Kinzler, K. W. & 2 others, Papadopoulos, N. & Vogelstein, B., Mar 3 2020, In : Proceedings of the National Academy of Sciences of the United States of America. 117, 9, p. 4858-4863 6 p.

Research output: Contribution to journalArticle