Find Research Outputs

2019

Allosteric modulation of sigma receptors by BH3 mimetics ABT-737, ABT-263 (Navitoclax) and ABT-199 (Venetoclax)

Lever, J. R. & Fergason-Cantrell, E. A., Apr 1 2019, In : Pharmacological Research. 142, p. 87-100 14 p.

Research output: Contribution to journalArticle

Pentazocine
B-Cell Lymphoma
Membranes
Brain
Guinea Pigs

Allowing adolescents to weigh benefits and burdens of high-stakes therapies

Puri, K., Malek, J., De La Uz, C. M., Lantos, J., Cabrera, A. G. & Frugé, E., Jan 1 2019, In : Pediatrics. 144, 1, e20183714.

Research output: Contribution to journalArticle

Long QT Syndrome
Defibrillators
Mothers
Syncope
Shock

A longitudinal study of Ebola sequelae in Liberia

PREVAIL III Study Group, Mar 7 2019, In : New England Journal of Medicine. 380, 10, p. 924-934 11 p.

Research output: Contribution to journalArticle

Liberia
Longitudinal Studies
Survivors
Uveitis
Ebolavirus

A longitudinal study of the association between persistent pathogens and incident depression among older U.S. Latinos

Simanek, A. M., Zheng, C., Yolken, R. H., Haan, M. & Aiello, A. E., May 1 2019, In : Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 74, 5, p. 634-641 8 p.

Research output: Contribution to journalArticle

Open Access
Hispanic Americans
Longitudinal Studies
Depression
Cytomegalovirus
C-Reactive Protein

A Long Road

Ashar, B., Jan 1 2019, (Accepted/In press) In : Medical Clinics of North America.

Research output: Contribution to journalEditorial

Weights and Measures
Counseling
Sleep
Healthy Lifestyle
Public Opinion

A Look Beyond Statins and Ezetimibe: a Review of Other Lipid-Lowering Treatments for Cardiovascular Disease Prevention in High-Risk Patients

Sabouret, P., Angoulvant, D., Pathak, A., Costa, F., Pezel, T. & Michos, E. D., Nov 1 2019, In : Current Cardiovascular Risk Reports. 13, 11, 32.

Research output: Contribution to journalReview article

Hydroxymethylglutaryl-CoA Reductase Inhibitors
Cardiovascular Diseases
Lipids
citrate (pro-3S)-lyase
Therapeutics

Alopecia a potential adverse side effect of albendazole use in alpacas

Gomez-Puerta, L. A., Carrasco, J., Vargas-Calla, A. M., Lopez-Urbina, M. T. & Gonzalez, A., Aug 1 2019, In : Veterinary Parasitology: Regional Studies and Reports. 17, 100297.

Research output: Contribution to journalArticle

New World Camelids
Albendazole
albendazole
alopecia
alpacas

A low-cost quantitative continuous measurement of movements in the extremities of people with Parkinson's disease

McKay, G. N., Harrigan, T. & Brasic, J. R., Jan 1 2019, In : MethodsX. 6, p. 169-189 21 p.

Research output: Contribution to journalArticle

Parkinson Disease
Extremities
Costs and Cost Analysis
Costs
Videotape Recording

Alpha2B-Adrenergic Receptor Overexpression in the Brain Potentiate Air Pollution-induced Behavior and Blood Pressure Changes

Rao, X., Asico, L. D., Zanos, P., Mahabeleshwar, G. H., Singh Gangwar, R., Xia, C., Duan, L., Cisse, Y. M., Rengasamy, P., Jose, P. A., Gould, T. D., Nelson, R., Biswal, S., Chen, L. C., Zhong, J. & Rajagopalan, S., May 1 2019, In : Toxicological sciences : an official journal of the Society of Toxicology. 169, 1, p. 95-107 13 p.

Research output: Contribution to journalArticle

Blood pressure
Air Pollution
Air pollution
Adrenergic Receptors
Brain

Alpha-synuclein deposition within sympathetic noradrenergic neurons is associated with myocardial noradrenergic deficiency in neurogenic orthostatic hypotension

Isonaka, R., Rosenberg, A. Z., Sullivan, P., Corrales, A., Holmes, C., Sharabi, Y. & Goldstein, D. S., Apr 1 2019, In : Hypertension. 73, 4, p. 910-918 9 p.

Research output: Contribution to journalArticle

Open Access
Lewy Body Disease
Adrenergic Neurons
alpha-Synuclein
Orthostatic Hypotension
Sympathetic Nervous System

Alterations in non-type I collagen biomarkers in osteogenesis imperfecta

Nicol, L., Morar, P., Wang, Y., Henriksen, K., Sun, S., Karsdal, M., Smith, R., Nagamani, S. C. S., Shapiro, J., Lee, B. & Orwoll, E., Mar 1 2019, In : Bone. 120, p. 70-74 5 p.

Research output: Contribution to journalArticle

Osteogenesis Imperfecta
Collagen Type I
Collagen
Biomarkers
Extracellular Matrix

Alterations in the retinal vasculature occur in multiple sclerosis and exhibit novel correlations with disability and visual function measures

Murphy, O. C., Kwakyi, O., Iftikhar, M., Zafar, S., Lambe, J., Pellegrini, N., Sotirchos, E. S., Gonzalez-Caldito, N., Ogbuokiri, E., Filippatou, A., Risher, H., Cowley, N., Feldman, S., Fioravante, N., Frohman, E. M., Frohman, T. C., Balcer, L. J., Prince, J. L., Channa, R., Calabresi, P. & 1 others, Saidha, S., Jan 1 2019, In : Multiple Sclerosis Journal.

Research output: Contribution to journalArticle

Multiple Sclerosis
Blood Vessels
Neuritis
Retinal Vessels
Optic Neuritis

Altered brain function in drug-naïve major depressive disorder patients with early-life maltreatment: A resting-state fMRI study

Xu, Z., Zhang, J., Wang, D., Wang, T., Zhang, S., Ren, X., Zhu, X., Kamiya, A., Fang, J. & Qu, M., Jan 1 2019, In : Frontiers in Psychiatry. 10, APR, 255.

Research output: Contribution to journalArticle

Open Access
Major Depressive Disorder
Magnetic Resonance Imaging
Brain
Pharmaceutical Preparations
Prefrontal Cortex

Altered frontal white matter asymmetry and its implications for cognition in schizophrenia: A tractography study

Gómez-Gastiasoro, A., Zubiaurre-Elorza, L., Peña, J., Ibarretxe-Bilbao, N., Rilo, O., Schretlen, D. & Ojeda, N., Jan 1 2019, In : NeuroImage: Clinical. 22, 101781.

Research output: Contribution to journalArticle

Open Access
Cognition
Schizophrenia
Anisotropy
Brain
Cerebrum

Altered Regional Brain Communities during High Order Cognitive Processes: Relation to Vigilance Decrement

Abbasi, N. I., Bose, R., Kumar, Y., Bodala, I. P., Bezerianos, A., Thakor, N. V. & Dragomir, A., May 16 2019, 9th International IEEE EMBS Conference on Neural Engineering, NER 2019. IEEE Computer Society, p. 631-634 4 p. 8717003. (International IEEE/EMBS Conference on Neural Engineering, NER; vol. 2019-March).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Brain
Electroencephalography
Experiments

Altered serotonergic circuitry in SSRI-resistant major depressive disorder patient-derived neurons

Vadodaria, K. C., Ji, Y., Skime, M., Paquola, A., Nelson, T., Hall-Flavin, D., Heard, K. J., Fredlender, C., Deng, Y., Elkins, J., Dani, K., Le, A. T., Marchetto, M. C., Weinshilboum, R. & Gage, F. H., Jan 1 2019, In : Molecular psychiatry.

Research output: Contribution to journalArticle

Major Depressive Disorder
Serotonin Uptake Inhibitors
Serotonergic Neurons
Neurons
Induced Pluripotent Stem Cells

Altered static and dynamic functional network connectivity in Alzheimer's disease and subcortical ischemic vascular disease: shared and specific brain connectivity abnormalities

Fu, Z., Caprihan, A., Chen, J., Du, Y., Adair, J. C., Sui, J., Rosenberg, G. A. & Calhoun, V. D., Jan 1 2019, In : Human Brain Mapping.

Research output: Contribution to journalArticle

Vascular Diseases
Alzheimer Disease
Brain
Vascular Dementia
Neuroimaging

Alternative dosing guidelines to improve outcomes in childhood tuberculosis: a mathematical modelling study

Radtke, K. K., Dooley, K. E., Dodd, P. J., Garcia-Prats, A. J., McKenna, L., Hesseling, A. C. & Savic, R. M., Sep 1 2019, In : The Lancet. Child & adolescent health. 3, 9, p. 636-645 10 p.

Research output: Contribution to journalArticle

Tuberculosis
Guidelines
Rifampin
Weights and Measures
Nutritional Status

Altruistic donation to improve survey responses: A global randomized trial

Cohen, A. J., Washington, S., Butler, C., Kamal, P., Patino, G., Tresh, A., Mena, J., Ndoye, M. & Breyer, B. N., Feb 28 2019, In : BMC Research Notes. 12, 1, 113.

Research output: Contribution to journalArticle

Open Access
Motivation
Research Personnel
Charities
Gift Giving
Aptitude

Alu insertion variants alter mRNA splicing

Payer, L. M., Steranka, J. P., Ardeljan, D., Walker, J. N., Fitzgerald, K., Calabresi, P., Cooper, T. A. & Burns, K., Jan 10 2019, In : Nucleic Acids Research. 47, 1, p. 421-431 11 p.

Research output: Contribution to journalArticle

Exons
Messenger RNA
RNA Splicing
Retroelements
Multiple Sclerosis

Alveolar soft-part sarcoma: Case demonstrating principles for uncommon vascular lesions

Leszczynska, M., Jodeh, D. S., Reed, D., Lynskey, E. M., Bittles, M. A., Mayer, J. L. R. & Rottgers, S. A., Oct 1 2019, In : Pediatrics International. 61, 10, p. 978-981 4 p.

Research output: Contribution to journalArticle

Alveolar Soft Part Sarcoma
Blood Vessels
Tongue
Biopsy
Neoplasms

Alzheimer's Disease and Neurotransmission Gene Variants: Focus on Their Effects on Psychiatric Comorbidities and Inflammatory Parameters

Porcelli, S., Calabrò, M., Crisafulli, C., Politis, A., Liappas, I., Albani, D., Raimondi, I., Forloni, G., Benedetti, F., Papadimitriou, G. N. & Serretti, A., Jan 1 2019, In : Neuropsychobiology.

Research output: Contribution to journalArticle

Open Access
Synaptic Transmission
Psychiatry
Comorbidity
Alzheimer Disease
Genes
marginal costs
mentoring
statistical analysis
Siblings
Costs and Cost Analysis

A mast cell–specific receptor is critical for granuloma induced by intrathecal morphine infusion

Zhang, T., Liu, R., Che, D., Pundir, P., Wang, N., Han, S., Cao, J., Lv, Y., Dong, H., Fang, F., Wang, J., Ma, P., Zhao, T., Lei, T., Dong, X. & He, L., Oct 1 2019, In : Journal of Immunology. 203, 7, p. 1701-1714 14 p.

Research output: Contribution to journalArticle

Granuloma
Morphine
Mast Cells
Chemokines
Antipain

A Mast-Cell-Specific Receptor Mediates Neurogenic Inflammation and Pain

Green, D. P., Limjunyawong, N., Gour, N., Pundir, P. & Dong, X., Feb 6 2019, In : Neuron. 101, 3, p. 412-420.e3

Research output: Contribution to journalArticle

Neurogenic Inflammation
Substance P
Mast Cells
Hyperalgesia
Chemokines

Ambient air pollution and pulmonary vascular volume on computed tomography: The MESA Air Pollution and Lung cohort studies

Aaron, C. P., Hoffman, E. A., Kawut, S. M., Austin, J. H. M., Budoff, M., Michos, E. D., Stukovsky, K. H., Sack, C., Szpiro, A. A., Watson, K. D., Kaufman, J. D. & Barr, R. G., Jun 1 2019, In : European Respiratory Journal. 53, 6, 1802116.

Research output: Contribution to journalArticle

Open Access
Cone-Beam Computed Tomography
Air Pollution
Soot
Nitrogen Dioxide
Blood Vessels

Ambient air pollution and variation in multiple domains of asthma morbidity among Peruvian children

and the GASP Study Investigators, Mar 1 2019, In : Annals of the American Thoracic Society. 16, 3, p. 348-355 8 p.

Research output: Contribution to journalArticle

Air Pollution
Asthma
Morbidity
Patient Acceptance of Health Care
Quality of Life

Ambient Fine Aerosol Concentrations in Multiple Metrics in Taconite Mining Operations

Huynh, T., Ramachandran, G., Quick, H., Hwang, J., Raynor, P. C., Alexander, B. H. & Mandel, J. H., Jan 7 2019, In : Annals of Work Exposures and Health. 63, 1, p. 77-90 14 p.

Research output: Contribution to journalArticle

Aerosols
Air
Particulate Matter
Dust
Calibration

AMBIsome Therapy Induction OptimisatioN (AMBITION): High dose AmBisome for cryptococcal meningitis induction therapy in sub-Saharan Africa: Economic evaluation protocol for a randomised controlled trial-based equivalence study

Ponatshego, P. L., Lawrence, D. S., Youssouf, N., Molloy, S. F., Alufandika, M., Bango, F., Boulware, D. R., Chawinga, C., Dziwani, E., Gondwe, E., Hlupeni, A., Hosseinipour, M. C., Kanyama, C., Meya, D. B., Mosepele, M., Muthoga, C., Muzoora, C. K., Mwandumba, H., Ndhlovu, C. E., Rajasingham, R. & 18 others, Sayed, S., Shamu, S., Tsholo, K., Tugume, L., Williams, D., Maheswaran, H., Shiri, T., Boyer-Chammard, T., Loyse, A., Chen, T., Wang, D., Lortholary, O., Lalloo, D. G., Meintjes, G., Jaffar, S., Harrison, T. S., Jarvis, J. N. & Niessen, L., Apr 1 2019, In : BMJ open. 9, 4, e026288.

Research output: Contribution to journalArticle

Cryptococcal Meningitis
Africa South of the Sahara
Cost-Benefit Analysis
Randomized Controlled Trials
Amphotericin B

A mechanism of resistance to antibody-targeted immune attack

Aldeghaither, D. S., Zahavi, D. J., Murray, J. C., Fertig, E., Graham, G. T., Zhang, Y. W., O'Connell, A., Ma, J., Jablonski, S. A. & Weiner, L. M., Feb 1 2019, In : Cancer immunology research. 7, 2, p. 230-243 14 p.

Research output: Contribution to journalArticle

Antibody-Dependent Cell Cytotoxicity
Antibodies
Epidermal Growth Factor Receptor
Synapses
Immune System

A Medicinal Chemist's Perspective on Transitioning from Industry to Academic Drug Discovery

Barrow, J., May 9 2019, In : ACS Medicinal Chemistry Letters. 10, 5, p. 687-689 3 p.

Research output: Contribution to journalReview article

Translational Medical Research
Drug Industry
Drug Discovery
Industry
Pharmaceutical Preparations
Open Access
Electroacupuncture
Ileus
Inflammation
Pain
Gastric Emptying
Nerve Growth Factor
Opioid Analgesics
Electric Stimulation
Rodentia
Stomach
Open Access
Autonomic Pathways
Gastroesophageal Reflux
Respiration
Lower Esophageal Sphincter
Acetylcholine

American Academy of Nursing on Policy position statement: Disaster preparedness for older adults

Spurlock, W. R., Rose, K., Veenema, T. G., Sinha, S. K., Gray-Miceli, D., Hitchman, S., Foster, N., Slepski-Nash, L. & Miller, E. T., Jan 1 2019, In : Nursing outlook. 67, 1, p. 118-121 4 p.

Research output: Contribution to journalArticle

Disasters
Nursing

American and European Hypertension Guidelines: Finding Common Ground

Yang, E., Sharma, G. & Ram, V., Apr 15 2019, In : American Journal of Cardiology. 123, 8, p. 1378-1382 5 p.

Research output: Contribution to journalEditorial

Guidelines
Hypertension

American Board of Thoracic Surgery 10-Year Maintenance of Certification Exam Improves and Validates Knowledge Acquisition

Colson, Y. L., Putnam, J. B., Yang, S. C., Fann, J. I., Vaporciyan, A. A., Dearani, J. A., Jones, D. R., Allen, M. S., Meyers, B. F., Wright, C. D., Shemin, R. J., Baumgartner, W. A. & Fullerton, D. A., Jan 1 2019, (Accepted/In press) In : Annals of Thoracic Surgery.

Research output: Contribution to journalArticle

Certification
Thoracic Surgery
Maintenance
Thorax
Learning

American cohort to study HIV acquisition among transgender women in high-risk areas (the LITE study): Protocol for a multisite prospective cohort study in the eastern and southern United States

American Cohort To Study HIV Acquisition Among Transgender Women (LITE), Jan 1 2019, In : Journal of medical Internet research. 21, 10, e14704.

Research output: Contribution to journalArticle

Open Access
Transgender Persons
Cohort Studies
HIV
Prospective Studies
Technology

American Head and Neck Society Endocrine Surgery Section update on parathyroid imaging for surgical candidates with primary hyperparathyroidism

Zafereo, M., Yu, J., Angelos, P., Brumund, K., Chuang, H. H., Goldenberg, D., Lango, M., Perrier, N., Randolph, G., Shindo, M. L., Singer, M., Smith, R., Stack, B. C., Steward, D., Terris, D. J., Vu, T., Yao, M. & Tufano, R. P., Jan 1 2019, In : Head and Neck.

Research output: Contribution to journalReview article

Primary Hyperparathyroidism
Four-Dimensional Computed Tomography
Neck
Insurance
Consumer Organizations

A meta-analysis of genome-wide association studies identifies multiple longevity genes

Deelen, J., Evans, D. S., Arking, D. E., Tesi, N., Nygaard, M., Liu, X., Wojczynski, M. K., Biggs, M. L., van der Spek, A., Atzmon, G., Ware, E. B., Sarnowski, C., Smith, A. V., Seppälä, I., Cordell, H. J., Dose, J., Amin, N., Arnold, A. M., Ayers, K. L., Barzilai, N. & 64 others, Becker, E. J., Beekman, M., Blanché, H., Christensen, K., Christiansen, L., Collerton, J. C., Cubaynes, S., Cummings, S. R., Davies, K., Debrabant, B., Deleuze, J. F., Duncan, R., Faul, J. D., Franceschi, C., Galan, P., Gudnason, V., Harris, T. B., Huisman, M., Hurme, M. A., Jagger, C., Jansen, I., Jylhä, M., Kähönen, M., Karasik, D., Kardia, S. L. R., Kingston, A., Kirkwood, T. B. L., Launer, L. J., Lehtimäki, T., Lieb, W., Lyytikäinen, L. P., Martin-Ruiz, C., Min, J., Nebel, A., Newman, A. B., Nie, C., Nohr, E. A., Orwoll, E. S., Perls, T. T., Province, M. A., Psaty, B. M., Raitakari, O. T., Reinders, M. J. T., Robine, J. M., Rotter, J. I., Sebastiani, P., Smith, J., Sørensen, T. I. A., Taylor, K. D., Uitterlinden, A. G., van der Flier, W., van der Lee, S. J., van Duijn, C. M., van Heemst, D., Vaupel, J. W., Weir, D., Ye, K., Zeng, Y., Zheng, W., Holstege, H., Kiel, D. P., Lunetta, K. L., Slagboom, P. E. & Murabito, J. M., Dec 1 2019, In : Nature communications. 10, 1, 3669.

Research output: Contribution to journalArticle

Open Access
phenotype
genome
gene expression
Genome-Wide Association Study
Gene expression

A meta-analysis of two high-risk prospective cohort studies reveals autism-specific transcriptional changes to chromatin, autoimmune, and environmental response genes in umbilical cord blood

Mordaunt, C. E., Park, B. Y., Bakulski, K. M., Feinberg, J. I., Croen, L. A., Ladd-Acosta, C., Newschaffer, C. J., Volk, H. E., Ozonoff, S., Hertz-Picciotto, I., Lasalle, J. M., Schmidt, R. J. & Fallin, M. D., Oct 24 2019, In : Molecular Autism. 10, 1, 36.

Research output: Contribution to journalArticle

Open Access
Autistic Disorder
Autoimmunity
Fetal Blood
Chromatin
Meta-Analysis

A method for building a genome-connectome bipartite graph model

Yu, Q., Chen, J., Du, Y., Sui, J., Damaraju, E., Turner, J. A., van Erp, T. G. M., Macciardi, F., Belger, A., Ford, J. M., McEwen, S., Mathalon, D. H., Mueller, B. A., Preda, A., Vaidya, J., Pearlson, G. D. & Calhoun, V. D., May 15 2019, In : Journal of Neuroscience Methods. 320, p. 64-71 8 p.

Research output: Contribution to journalArticle

Connectome
Single Nucleotide Polymorphism
Schizophrenia
Genome
Brain
Decision Trees
beta-Lactamases
Bacteremia
Infection
Pharmaceutical Preparations

A methodology for discovering novel brain-relevant peptides: Combination of ribosome profiling and peptidomics

Tharakan, R., Kreimer, S., Ubaida-Mohien, C., Lavoie, J., Olexiouk, V., Menschaert, G., Ingolia, N. T., Cole, R. N., Ishizuka, K., Sawa, A. & Nucifora, L., Jan 1 2019, In : Neuroscience Research.

Research output: Contribution to journalArticle

Ribosomes
Peptides
Brain
Physiological Phenomena
Brain Diseases

A method to compare the discriminatory power of data-driven methods: Application to ICA and IVA

Levin-Schwartz, Y., Calhoun, V. D. & Adalı, T., Jan 1 2019, In : Journal of Neuroscience Methods. 311, p. 267-276 10 p.

Research output: Contribution to journalArticle

Magnetic Resonance Imaging
Schizophrenia
Power (Psychology)
Task Performance and Analysis
Psychiatry

A microfluidic assay for the quantification of the metastatic propensity of breast cancer specimens

Yankaskas, C. L., Thompson, K. N., Paul, C. D., Vitolo, M. I., Mistriotis, P., Mahendra, A., Bajpai, V. K., Shea, D. J., Manto, K. M., Chai, A. C., Varadarajan, N., Kontrogianni-Konstantopoulos, A., Martin, S. S. & Konstantopoulos, K., Jan 1 2019, In : Nature biomedical engineering.

Research output: Contribution to journalArticle

Microfluidics
Assays
Cells
Breast Neoplasms
Neoplasm Metastasis

A microphysiological model of the bronchial airways reveals the interplay of mechanical and biochemical signals in bronchospasm

Kilic, O., Yoon, A., Shah, S. R., Yong, H. M., Ruiz-Valls, A., Chang, H., Panettieri, R. A., Liggett, S. B., Quiñones-Hinojosa, A., An, S. & Levchenko, A., Jan 1 2019, In : Nature Biomedical Engineering.

Research output: Contribution to journalArticle

Bronchial Spasm
Asthma
Smooth Muscle
Epithelial Cells
Molecular Models

Amide proton transfer contrast distribution in different brain regions in young healthy subjects

Sartoretti, T., Sartoretti, E., Wyss, M., Schwenk, Á., Najafi, A., Binkert, C., Reischauer, C., Zhou, J., Jiang, S., Becker, A. S. & Sartoretti-Schefer, S., Jan 1 2019, In : Frontiers in Neuroscience. 13, MAY, 520.

Research output: Contribution to journalArticle

Open Access
Amides
Protons
Healthy Volunteers
Brain
Magnetic Resonance Imaging