Find Research Outputs


Activated Microglia Targeting Dendrimer-Minocycline Conjugate as Therapeutics for Neuroinflammation

Sharma, R., Kim, S. Y., Sharma, A., Zhang, Z., Kambhampati, S. P., Kannan, S. & Kannan, R. M. Nov 15 2017 In : Bioconjugate Chemistry. 28, 11, p. 2874-2886 13 p.

Research output: Research - peer-reviewArticle

Pharmaceutical Preparations

Activating the AKT2-nuclear factor-κB-lipocalin-2 axis elicits an inflammatory response in age-related macular degeneration

Ghosh, S., Shang, P., Yazdankhah, M., Bhutto, I., Hose, S., Montezuma, S. R., Luo, T., Chattopadhyay, S., Qian, J., Lutty, G. A., Ferrington, D. A., Zigler, J. S. & Sinha, D. 2017 (Accepted/In press) In : Journal of Pathology.

Research output: Research - peer-reviewArticle

Macular Degeneration
Immune System

Activation mechanisms of the E3 ubiquitin ligase parkin

Panicker, N., Dawson, V. L. & Dawson, T. M. Sep 15 2017 In : Biochemical Journal. 474, 18, p. 3075-3086 12 p.

Research output: Research - peer-reviewReview article

Ubiquitin-Protein Ligases
Chemical activation
Parkinson Disease

Activation of endoplasmic reticulum stress response by enhanced polyamine catabolism is important in the mediation of cisplatin-induced acute kidney injury

Zahedi, K., Barone, S., Destefano-Shields, C., Brooks, M., Murray-Stewart, T., Dunworth, M., Li, W., Doherty, J. R., Hall, M. A., Smith, R. D., Cleveland, J. L., Casero, R. A. & Soleimani, M. Sep 1 2017 In : PLoS ONE. 12, 9, e0184570

Research output: Research - peer-reviewArticle

endoplasmic reticulum
stress response

Activation of human basophils by A549 lung epithelial cells reveals a novel IgE-dependent response independent of allergen

Schroeder, J. T. & Bieneman, A. P. Aug 1 2017 In : Journal of Immunology. 199, 3, p. 855-865 11 p.

Research output: Research - peer-reviewArticle

Immunoglobulin E
Epithelial Cells

Activation of Langerhans cells promotes the inflammation in imiquimod-induced psoriasis-like dermatitis

Xiao, C., Zhu, Z., Sun, S., Gao, J., Fu, M., Liu, Y., Wang, G., Yao, X. & Li, W. Mar 1 2017 In : Journal of Dermatological Science. 85, 3, p. 170-177 8 p.

Research output: Research - peer-reviewArticle

Langerhans Cells

Activation of Nrf2 Signaling Augments Vesicular Stomatitis Virus Oncolysis via Autophagy-Driven Suppression of Antiviral Immunity

Olagnier, D., Lababidi, R. R., Hadj, S. B., Sze, A., Liu, Y., Naidu, S. D., Ferrari, M., Jiang, Y., Chiang, C., Beljanski, V., Goulet, M. L., Knatko, E. V., Dinkova-Kostova, A. T., Hiscott, J. & Lin, R. Aug 2 2017 In : Molecular Therapy. 25, 8, p. 1900-1916 17 p.

Research output: Research - peer-reviewArticle

Vesicular Stomatitis
Antiviral Agents

Activation of tumor suppressor LKB1 by honokiol abrogates cancer stem-like phenotype in breast cancer via inhibition of oncogenic Stat3

Sengupta, S. , Nagalingam, A. , Muniraj, N. , Bonner, M. Y. , Mistriotis, P. , Afthinos, A. , Kuppusamy, P. , Lanoue, D. , Cho, S. , Korangath, P. , Shriver, M. , Begum, A. , Merino, V. F. , Huang, C. Y. , Arbiser, J. L. , Matsui, W. , Györffy, B. , Konstantopoulos, K. , Sukumar, S. , Marignani, P. A. & 2 others Saxena, N. K. & Sharma, D. Oct 12 2017 In : Oncogene. 36, 41, p. 5709-5721 13 p.

Research output: Research - peer-reviewArticle

Breast Neoplasms

Active phantoms: A paradigm for ultrasound calibration using phantom feedback

Cheng, A., Guo, X., Zhang, H. K., Kang, H. J., Etienne-Cummings, R. & Boctor, E. M. Jul 1 2017 In : Journal of Medical Imaging. 4, 3, 035001

Research output: Research - peer-reviewArticle

Image quality

Active Sensing: The Rat's Nose Dances in Step with Whiskers, Head, and Breath

Severson, K. S. & O'Connor, D. H. Mar 6 2017 In : Current Biology. 27, 5, p. R183-R185

Research output: Research - peer-reviewShort survey

touch (sensation)

Active Site Binding Is Not Sufficient for Reductive Deiodination by Iodotyrosine Deiodinase

Ingavat, N., Kavran, J. M., Sun, Z. & Rokita, S. E. Feb 28 2017 In : Biochemistry. 56, 8, p. 1130-1139 10 p.

Research output: Research - peer-reviewArticle

Iodide Peroxidase
Catalytic Domain
Binding Sites
Chronic Renal Insufficiency

Active Surveillance Versus Watchful Waiting for Localized Prostate Cancer: A Model to Inform Decisions

Loeb, S., Zhou, Q., Siebert, U., Rochau, U., Jahn, B., Mühlberger, N., Carter, H. B., Lepor, H. & Braithwaite, R. S. 2017 (Accepted/In press) In : European Urology.

Research output: Research - peer-reviewArticle

Watchful Waiting
Prostatic Neoplasms
Quality of Life
Quality-Adjusted Life Years

Active yeast ribosome preparation using monolithic anion exchange chromatography

Munoz, A. M., Yourik, P., Rajagopal, V., Nanda, J. S., Lorsch, J. R. & Walker, S. E. Feb 1 2017 In : RNA Biology. 14, 2, p. 188-196 9 p.

Research output: Research - peer-reviewArticle

In Vitro Techniques

Activin receptor type 2A (ACVR2A) functions directly in osteoblasts as a negative regulator of bone mass

Goh, B. C., Singhal, V., Herrera, A. J., Tomlinson, R. E., Kim, S., Faugere, M. C., Germain-Lee, E. L., Clemens, T. L., Lee, S. J. & Digirolamo, D. J. 2017 In : Journal of Biological Chemistry. 292, 33, p. 13809-13822 14 p.

Research output: Research - peer-reviewArticle

Activin Receptors
Bone and Bones

Activity of sulfa drugs and their combinations against stationary phase b. Burgdorferi in vitro

Feng, J., Zhang, S., Shi, W. & Zhang, Y. Mar 22 2017 In : Antibiotics. 6, 1, 10

Research output: Research - peer-reviewReview article

Drug Combinations
Pharmaceutical Preparations
In Vitro Techniques
Anti-Bacterial Agents

Activity restriction recommendations and outcomes after reconstructive pelvic surgery: A randomized controlled trial

Mueller, M. G., Lewicky-Gaupp, C., Collins, S. A., Abernethy, M. G., Alverdy, A. & Kenton, K. 2017 In : Obstetrics and Gynecology. 129, 4, p. 608-614 7 p.

Research output: Research - peer-reviewArticle

Reconstructive Surgical Procedures
Randomized Controlled Trials
Pelvic Floor
Patient Satisfaction

Activity restriction recommendations and outcomes after reconstructive pelvic surgery: A randomized controlled trial

Mueller, M. G., Lewicky-Gaupp, C., Collins, S. A., Abernethy, M. G., Alverdy, A. & Kenton, K. 2017 In : Obstetrical and Gynecological Survey. 72, 7, p. 410-411 2 p.

Research output: Research - peer-reviewComment/debate

A cullin 4B-RING E3 ligase complex fine-tunes pancreatic δ cell paracrine interactions

Li, Q. , Cui, M. , Yang, F. , Li, N. , Jiang, B. , Yu, Z. , Zhang, D. , Wang, Y. , Zhu, X. , Hu, H. , Li, P. S. , Ning, S. L. , Wang, S. , Qi, H. , Song, H. , He, D. , Lin, A. , Zhang, J. , Liu, F. , Zhao, J. & 6 others Gao, L., Yi, F., Xue, T., Sun, J. P., Gong, Y. & Yu, X. Jun 30 2017 In : Journal of Clinical Investigation. 127, 7, p. 2631-2646 16 p.

Research output: Research - peer-reviewArticle

Cullin Proteins
Ubiquitin-Protein Ligases
Somatostatin-Secreting Cells
Cell Communication

Acupuncture for the Treatment of Chronic Pain in the Military Population

Plunkett, A., Beltran, T., Haley, C., Kurihara, C., McCoart, A., Chen, L., Wilkinson, I. & Cohen, S. P. 2017 In : Clinical Journal of Pain. 33, 10, p. 939-943 5 p.

Research output: Research - peer-reviewArticle

Acupuncture Therapy
Chronic Pain
Mucociliary Clearance
Propylene Glycol
Electronic Cigarettes
Tobacco Products
Street Drugs
Brain Injuries
Substance-Related Disorders
Young Adult

Acute Coronary Syndrome Screening and Diagnostic Practice Variation

Yiadom, M. Y. A. B. , Liu, X. , McWade, C. M. , Liu, D. , Storrow, A. B. , Herdon-Meadors, P. , Shuler, W. , Goldlust, E. , Sawyer, C. , Wong, A. , Tanski, M. , Patterson, B. , Wiener, D. , Baugh, C. W. , Carlson, J. N. , Strout, T. D. , Hill, C. D. , Turturro, M. , Whitcomb, C. , Dunlap, P. & 44 others McPheeters, R. A., Gavin, N., Hansen, J., Web, C., Calichman, M., Chen, P., Salazar, G., Shepard, B., Milligan, B., Rudd, K., Lee, A., Spiegel, T., Garvey, L., Rodi, S., Caterino, J., Furlong, B., Dubin, J., Imperato, J., Vohra, A., Mills, A., Hager, D., Podolsky, S., Novotny, A., Hartsfield, L., Bosco, S., McDermott, D. B., Pacella, C., Mazzeo, A., Guyette, M., McCoy, T., Gronczewski, C., Riordan, J., Leahy, J., Hocker, M., Mirarchi, F., Bhatia, M. C., Paul Cook, J., Ramanujan, V., Acquaye, J., Means, T., Strawn, C., Jackson, L., Davis, B. & and the ED Operations Study Group 2015 Jun 1 2017 In : Academic Emergency Medicine. 24, 6, p. 701-709 9 p.

Research output: Research - peer-reviewArticle

Acute Coronary Syndrome
Hospital Emergency Service

Acute coronary syndrome with a culprit lesion in a single coronary artery

Witkowska, A. B., Skowroński, J. D., Jasek, S. Ł., Lazarczyk, H., Janowski, M. & Witkowski, A. 2017 In : Polish Archives of Internal Medicine. 127, 9, p. 639-640 2 p.

Research output: Research - peer-reviewComment/debate

Acute Coronary Syndrome
Coronary Vessels

Acute exacerbations and lung function loss in smokers with and without chronic obstructive pulmonary disease

Dransfield, M. T., Kunisaki, K. M., Strand, M. J., Anzueto, A., Bhatt, S. P., Bowler, R. P., Criner, G. J., Curtis, J. L., Hanania, N. A., Nath, H., Putcha, N., Roark, S. E., Wan, E. S., Washko, G. R., Wells, J. M., Wendt, C. H. & Make, B. J. Feb 1 2017 In : American Journal of Respiratory and Critical Care Medicine. 195, 3, p. 324-330 7 p.

Research output: Research - peer-reviewArticle

Chronic Obstructive Pulmonary Disease
Confidence Intervals
Health Care Costs
Olfactory Mucosa
Tumor Necrosis Factor-alpha
Neural Stem Cells
Tumor Necrosis Factor Receptors

Acute Kidney Injury, Risk Factors, and Prognosis in Hospitalized HIV-Infected Adults in South Africa, Compared by Tenofovir Exposure

Seedat, F., Martinson, N., Motlhaoleng, K., Abraham, P., Mancama, D., Naicker, S. & Variava, E. Jan 1 2017 In : AIDS Research and Human Retroviruses. 33, 1, p. 33-40 8 p.

Research output: Research - peer-reviewArticle

South Africa
Acute Kidney Injury

Acute kidney injury and 1-year mortality after left ventricular assist device implantation

Muslem, R., Caliskan, K., Akin, S., Sharma, K., Gilotra, N. A., Constantinescu, A. A., Houston, B., Whitman, G., Tedford, R. J., Hesselink, D. A., Bogers, A. J. J. C., Russell, S. D. & Manintveld, O. C. Jan 1 2017 (Accepted/In press) In : Journal of Heart and Lung Transplantation.

Research output: Research - peer-reviewArticle

Heart-Assist Devices
Acute Kidney Injury
Heart Ventricles

Acute Kidney Injury Following Acute Ischemic Stroke and Intracerebral Hemorrhage: A Meta-Analysis of Prevalence Rate and Mortality Risk

Zorrilla-Vaca, A., Ziai, W., Connolly, E. S., Geocadin, R., Thompson, R. & Rivera-Lara, L. Nov 24 2017 (Accepted/In press) In : Cerebrovascular Diseases. p. 1-9 9 p.

Research output: Research - peer-reviewArticle

Cerebral Hemorrhage
Acute Kidney Injury

Acute kidney injury in patients on SGLT2 inhibitors: A propensity-matched analysis

Nadkarni, G. N., Ferrandino, R., Chang, A., Surapaneni, A., Chauhan, K., Poojary, P., Saha, A., Ferket, B., Grams, M. E. & Coca, S. G. Nov 1 2017 In : Diabetes Care. 40, 11, p. 1479-1485 7 p.

Research output: Research - peer-reviewArticle

Sodium-Glucose Transport Proteins
Acute Kidney Injury
Kidney Diseases
Type 2 Diabetes Mellitus

Acute myeloid leukemia, version 3.2017: Clinical practice guidelines in oncology

O'Donnell, M. R. , Tallman, M. S. , Abboud, C. N. , Altman, J. K. , Appelbaum, F. R. , Arber, D. A. , Bhatt, V. , Bixby, D. , Blum, W. , Coutre, S. E. , De Lima, M. , Fathi, A. T. , Fiorella, M. , Foran, J. M. , Gore, S. D. , Hall, A. C. , Kropf, P. , Lancet, J. , Maness, L. J. , Marcucci, G. & 14 others Martin, M. G., Moore, J. O., Olin, R., Peker, D., Pollyea, D. A., Pratz, K., Ravandi, F., Shami, P. J., Stone, R. M., Strickland, S. A., Wang, E. S., Wieduwilt, M., Gregory, K. & Ogba, N. Jul 1 2017 In : JNCCN Journal of the National Comprehensive Cancer Network. 15, 7, p. 926-957 32 p.

Research output: Research - peer-reviewReview article

Practice Guidelines
Acute Myeloid Leukemia

Acute myeloid leukemia and myelodysplastic syndrome after adjuvant chemotherapy: A population-based study among older breast cancer patients

Rosenstock, A. S., Niu, J., Giordano, S. H., Zhao, H., Wolff, A. C. & Chavez-Macgregor, M. Jan 1 2017 (Accepted/In press) In : Cancer.

Research output: Research - peer-reviewArticle

Myelodysplastic Syndromes
Adjuvant Chemotherapy
Acute Myeloid Leukemia
Health Services
Breast Neoplasms

Acute myeloid leukemia in the elderly: therapeutic options and choice

Webster, J. A. & Pratz, K. W. Jun 2 2017 (Accepted/In press) In : Leukemia and Lymphoma. p. 1-14 14 p.

Research output: Research - peer-reviewArticle

Acute Myeloid Leukemia
Age Groups

Acute-onset chest pain in a 17-year-old female adolescent with systemic lupus erythematosus

Mangus, C. W., Fatusin, O. & Ngo, T. L. 2017 In : Pediatric Emergency Care. 33, 5, p. 346-349 4 p.

Research output: Research - peer-reviewArticle

Chest Pain
Systemic Lupus Erythematosus
Pneumococcal Infections
Cardiac Tamponade

Acute Pain Characteristics in Patients with and without Chronic Pain following Lower Extremity Injury

Griffioen, M. A., Greenspan, J. D., Johantgen, M., Von Rueden, K., O'Toole, R. V., Dorsey, S. G. & Renn, C. L. Feb 1 2017 In : Pain Management Nursing. 18, 1, p. 33-41 9 p.

Research output: Research - peer-reviewArticle

Acute Pain
Chronic Pain
Lower Extremity
Wounds and Injuries

Acute pancreatitis patient registry to examine novel therapies in clinical experience (APPRENTICE): An international, multicenter consortium for the study of acute pancreatitis

Papachristou, G. I. , Machicado, J. D. , Stevens, T. , Goenka, M. K. , Ferreira, M. , Gutierrez, S. C. , Singh, V. K. , Kamal, A. , Gonzalez-Gonzalez, J. A. , Pelaez-Luna, M. , Gulla, A. , Zarnescu, N. O. , Triantafyllou, K. , Barbu, S. T. , Easler, J. , Ocampo, C. , Capurso, G. , Archibugi, L. , Cote, G. A. , Lambiase, L. & 13 others Kochhar, R., Chua, T., Tiwari, S. C., Nawaz, H., Park, W. G., De-Madaria, E., Lee, P. J., Wu, B. U., Greer, P. J., Dugum, M., Koutroumpakis, E., Akshintala, V. & Gougol, A. 2017 In : Annals of Gastroenterology. 30, 1, p. 106-113 8 p.

Research output: Research - peer-reviewArticle

Multicenter Studies
Randomized Controlled Trials

Acute posterior multifocal placoid pigment epitheliopathy associatedwith drug reaction with eosinophilia and systemic symptoms syndrome

Zhang, A. Y., Yohannan, J., Goldberg, M. F. & Han, I. C. Feb 1 2017 In : JAMA Ophthalmology. 135, 2, p. 169-171 3 p.

Research output: Research - peer-reviewLetter

Drug Hypersensitivity Syndrome

Acute Retinal Necrosis: Presenting Characteristics and Clinical Outcomes in a Cohort of Polymerase Chain Reaction–Positive Patients

Butler, N. J., Moradi, A., Salek, S. S., Burkholder, B. M., Leung, T. G., Dunn, J. P. & Thorne, J. E. Jul 1 2017 In : American Journal of Ophthalmology. 179, p. 179-189 11 p.

Research output: Research - peer-reviewArticle

Acute Retinal Necrosis Syndrome
Polymerase Chain Reaction
Retinal Detachment
Confidence Intervals

Acute stroke emergency management

George, P. & Lara, L. R. May 30 2017 Evidence-Based Critical Care: A Case Study Approach. Springer International Publishing, p. 303-314 12 p.

Research output: ResearchChapter


A cyber-linked undergraduate research experience in computational biomolecular structure prediction and design

Alford, R. F., Leaver-Fay, A., Gonzales, L., Dolan, E. L. & Gray, J. J. Dec 1 2017 In : PLoS Computational Biology. 13, 12, e1005837

Research output: Research - peer-reviewArticle

Molecular Conformation
Structure Prediction
Computational Biology

Adalimumab in the treatment of uveitis in juvenile idiopathic arthritis

Thorne, J. E. Apr 27 2017 In : New England Journal of Medicine. 376, 17, p. 1682-1683 2 p.

Research output: Research - peer-reviewShort survey

Adamantinoma-like Ewing sarcoma of the parotid gland: Cytopathologic findings and differential diagnosis

Lilo, M. T., Bishop, J. A., Olson, M. T. & Ali, S. Z. 2017 (Accepted/In press) In : Diagnostic Cytopathology.

Research output: Research - peer-reviewArticle

Ewing's Sarcoma
Parotid Gland
Differential Diagnosis
Epithelioid Cells

Adaptation of a Screening Tool for Perinatal Depression and Anxiety in Community-Based Maternal Health Services in Mali

Lasater, M. E., Beebe, M., Blomberg, K., Warren, N., Gresh, A., Hsih, K. & Winch, P. 2017 (Accepted/In press) In : Journal of Midwifery and Women's Health.

Research output: Research - peer-reviewArticle

Maternal Health Services

Adaptation to TKI treatment reactivates ERK signaling in tyrosine kinase–driven leukemias and other malignancies

Bruner, J. K., Ma, H. S., Li, L., Qin, A. C. R., Rudek, M. A., Jones, R. J., Levis, M. J., Pratz, K. W., Pratilas, C. A. & Small, D. Oct 15 2017 In : Cancer Research. 77, 20, p. 5554-5563 10 p.

Research output: Research - peer-reviewArticle

Protein-Tyrosine Kinases
Acute Myeloid Leukemia
Mitogen-Activated Protein Kinase Kinases

Adapting to the global shortage of cholera vaccines: Targeted single dose cholera vaccine in response to an outbreak in South Sudan

Parker, L. A., Rumunu, J., Jamet, C., Kenyi, Y., Lino, R. L., Wamala, J. F., Mpairwe, A. M., Ciglenecki, I., Luquero, F. J., Azman, A. S. & Cabrol, J. C. 2017 (Accepted/In press) In : The Lancet Infectious Diseases.

Research output: Research - peer-reviewArticle

Cholera Vaccines
Disease Outbreaks
South Sudan
Immunization Programs

Adapting to the Rapid Evolution of Healthcare from a Shared Perspective

Yang, W. & Huang, J. 2017 (Accepted/In press) In : World Neurosurgery.

Research output: Research - peer-reviewArticle

Institutional Ethics
Delivery of Health Care

Adaptive Enrichment Designs for Stroke Clinical Trials

Rosenblum, M. & Hanley, D. F. Jul 1 2017 In : Stroke. 48, 7, p. 2021-2025 5 p.

Research output: Research - peer-reviewReview article

Precision Medicine
Research Design
Randomized Controlled Trials

Adaptive estimation of personalized maximum tolerated dose in cancer Phase i clinical trials based on all toxicities and individual genomic profile

Chen, Z., Li, Z., Zhuang, R., Yuan, Y., Kutner, M., Owonikoko, T., Curran, W. J. & Kowalski, J. Jan 1 2017 In : PLoS ONE. 12, 1, e0170187

Research output: Research - peer-reviewArticle

clinical trials

Adaptive independent vector analysis for multi-subject complex-valued fMRI data

Kuang, L. D., Lin, Q. H., Gong, X. F., Cong, F. & Calhoun, V. D. Apr 1 2017 In : Journal of Neuroscience Methods. 281, p. 49-63 15 p.

Research output: Research - peer-reviewArticle

Magnetic Resonance Imaging
Normal Distribution

Adaptive resistance to anti-PD1 therapy by Tim-3 upregulation is mediated by the PI3K-Akt pathway in head and neck cancer

Shayan, G., Srivastava, R., Li, J., Schmitt, N., Kane, L. P. & Ferris, R. L. Jan 9 2017 (Accepted/In press) In : OncoImmunology.

Research output: Research - peer-reviewArticle

Head and Neck Neoplasms