Find Research Outputs

2018

A comprehensive evaluation of CHEK2 germline mutations in men with prostate cancer

Wu, Y., Yu, H., Zheng, S. L., Na, R., Mamawala, M., Landis, T., Wiley, K., Petkewicz, J., Shah, S., Shi, Z., Novakovic, K., McGuire, M., Brendler, C. B., Ding, Q., Helfand, B. T., Carter, H. B., Cooney, K. A., Isaacs, W. B. & Xu, J., Jun 1 2018, In : Prostate. 78, 8, p. 607-615 9 p.

Research output: Contribution to journalArticle

Germ-Line Mutation
Prostatic Neoplasms
Mutation
Exome
Kaplan-Meier Estimate

A Comprehensive Pan-Cancer Molecular Study of Gynecologic and Breast Cancers

The Cancer Genome Atlas Research Network, Apr 9 2018, In : Cancer Cell. 33, 4, p. 690-705.e9

Research output: Contribution to journalArticle

Breast Neoplasms
Atlases
Long Noncoding RNA
Decision Trees
Genome

A Comprehensive Risk Score to Predict Prolonged Hospital Length of Stay After Heart Transplantation

Crawford, T. C., Magruder, J. T., Grimm, J. C., Suarez-Pierre, A., Patel, N., Sciortino, C. M., Zehr, K. J., Mandal, K., Tedford, R. J., Russell, S. D., Conte, J. V., Higgins, R., Cameron, D. E. & Whitman, G., Jan 1 2018, In : Annals of Thoracic Surgery. 105, 1, p. 83-90 8 p.

Research output: Contribution to journalArticle

Heart Transplantation
Length of Stay
Hospitalization
Transplants
Cold Ischemia

A computational framework for complementary situational awareness (CSA) in surgical assistant robots

Chalasani, P., Deguet, A., Kazanzides, P. & Taylor, R. H., Apr 2 2018, Proceedings - 2nd IEEE International Conference on Robotic Computing, IRC 2018. Institute of Electrical and Electronics Engineers Inc., Vol. 2018-January. p. 9-16 8 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Situational Awareness
Minimally Invasive Surgery
Surgery
Anatomy
Robot

A Conserved Role for Serotonergic Neurotransmission in Mediating Social Behavior in Octopus

Edsinger, E. & Dolen, G., Oct 8 2018, In : Current Biology. 28, 19, p. 3136-3142.e4

Research output: Contribution to journalArticle

Octopodiformes
Octopodidae
Social Behavior
social behavior
Synaptic Transmission

A Contemporary Analysis of Heart Transplantation and Bridge-to-Transplant Mechanical Circulatory Support Outcomes in Cardiac Sarcoidosis

Crawford, T. C., Okada, D. R., Magruder, J. T., Fraser, C., Patel, N., Houston, B. A., Whitman, G., Mandal, K., Zehr, K. J., Higgins, R., Chen, E., Tandri, H., Kasper, E. K., Tedford, R. J., Russell, S. D. & Gilotra, N., Jan 1 2018, (Accepted/In press) In : Journal of Cardiac Failure.

Research output: Contribution to journalArticle

Heart Transplantation
Sarcoidosis
Transplants
Survival
Mortality

A contemporary framework of health equity applied to gynecologic cancer care: A Society of Gynecologic Oncology evidenced-based review

Temkin, S. M., Rimel, B. J., Bruegl, A. S., Gunderson, C. C., Beavis, A. & Doll, K. M., Apr 1 2018, In : Gynecologic oncology. 149, 1, p. 70-77 8 p.

Research output: Contribution to journalReview article

Neoplasms
Health
Social Determinants of Health
Population
Delivery of Health Care

A Convex Optimization Framework for Constrained Concurrent Motion Control of a Hybrid Redundant Surgical System

Alambeigi, F., Sefati, S. & Armand, M., Aug 9 2018, 2018 Annual American Control Conference, ACC 2018. Institute of Electrical and Electronics Engineers Inc., Vol. 2018-June. p. 1158-1165 8 p. 8430983

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Convex optimization
Motion control
Redundancy
Robotic arms
Degrees of freedom (mechanics)

A convolutional neural network to filter artifacts in spectroscopic MRI

Gurbani, S. S., Schreibmann, E., Maudsley, A. A., Cordova, J. S., Soher, B. J., Poptani, H., Verma, G., Barker, P. B., Shim, H. & Cooper, L. A. D., Jan 1 2018, (Accepted/In press) In : Magnetic Resonance in Medicine.

Research output: Contribution to journalArticle

Artifacts
Ionizing Radiation
Contrast Media
Area Under Curve
Protons

A correction for sample overlap in genome-wide association studies in a polygenic pleiotropy-informed framework

Schizophrenia and Bipolar Disorder Working Groups of the Psychiatric Genomics Consortium, Jun 25 2018, In : BMC Genomics. 19, 1, 494.

Research output: Contribution to journalArticle

Genome-Wide Association Study

A Cost Analysis of Universal versus Targeted Cholesterol Screening in Pediatrics

Smith, A. J., Turner, E. L., Kinra, S., Bodurtha, J. N. & Chien, A. T., May 1 2018, In : Journal of Pediatrics. 196, p. 201-207.e2

Research output: Contribution to journalArticle

Hyperlipidemias
Cholesterol
Pediatrics
Costs and Cost Analysis
LDL Lipoproteins

A cost minimization analysis of occupational therapy discharge planning for older adults: the HOME randomized controlled trial

Wales, K., Salkeld, G., Clemson, L., Lannin, N. A., Gitlin, L. N., Rubenstein, L., Howard, K., Howell, M. & Cameron, I. D., Mar 1 2018, (Accepted/In press) In : Clinical Rehabilitation.

Research output: Contribution to journalArticle

Patient Discharge
Occupational Therapy
Activities of Daily Living
Randomized Controlled Trials
Cost-Benefit Analysis

A coupled-clock system drives the automaticity of human sinoatrial nodal pacemaker cells

Tsutsui, K., Monfredi, O. J., Sirenko-Tagirova, S. G., Maltseva, L. A., Bychkov, R., Kim, M. S., Ziman, B. D., Tarasov, K. V., Tarasova, Y. S., Zhang, J., Wang, M., Maltsev, A. V., Brennan, J. A., Efimov, I. R., Stern, M. D., Maltsev, V. A. & Lakatta, E., Jun 12 2018, In : Science Signaling. 11, 534, eaap7608.

Research output: Contribution to journalArticle

Pacemakers
Clocks
Action Potentials
Cyclic AMP-Dependent Protein Kinases
Sinoatrial Node

Acquired Cystic Disease-associated Renal Cell Carcinoma (ACKD-RCC)-like Cysts

Sun, Y., Argani, P., Tickoo, S. K. & Epstein, J. I., Jul 13 2018, (Accepted/In press) In : American Journal of Surgical Pathology.

Research output: Contribution to journalArticle

Renal Cell Carcinoma
Cysts
Chronic Kidney Failure
Neoplasms
Calcium Oxalate

ACR Appropriateness Criteria® Chronic Chest Pain-Noncardiac Etiology Unlikely-Low to Intermediate Probability of Coronary Artery Disease

Expert Panel on Cardiac Imaging:, Nov 1 2018, In : Journal of the American College of Radiology. 15, 11, p. S283-S290

Research output: Contribution to journalArticle

Chest Pain
Chronic Pain
Coronary Artery Disease
Guidelines
Expert Testimony

ACR Appropriateness Criteria® Headache–Child

Expert Panel on Pediatric Imaging:, May 1 2018, In : Journal of the American College of Radiology. 15, 5, p. S78-S90

Research output: Contribution to journalArticle

Headache
Guidelines
Expert Testimony
Radiology
Neuroimaging

ACR Appropriateness Criteria® Radiologic Management of Uterine Leiomyomas

Expert Panel on Interventional Radiology:, May 1 2018, In : Journal of the American College of Radiology. 15, 5, p. S160-S170

Research output: Contribution to journalArticle

Leiomyoma
Therapeutics
Uterine Myomectomy
Uterine Artery Embolization
Guidelines

ACR Appropriateness Criteria® Sinusitis-Child

Expert Panel on Pediatric Imaging:, Nov 1 2018, In : Journal of the American College of Radiology. 15, 11, p. S403-S412

Research output: Contribution to journalArticle

Sinusitis
Guidelines
Expert Testimony
Standard of Care
Radiology

ACR Appropriateness Criteria® Suspected New-Onset and Known Nonacute Heart Failure

Expert Panel on Cardiac Imaging:, Nov 1 2018, In : Journal of the American College of Radiology. 15, 11, p. S418-S431

Research output: Contribution to journalArticle

Heart Failure
Echocardiography
Guidelines
Myocardial Contraction
Ventricular Dysfunction

A CRISPR way to restore hearing

Chien, W. W., Mar 29 2018, In : New England Journal of Medicine. 378, 13, p. 1255-1256 2 p.

Research output: Contribution to journalShort survey

Clustered Regularly Interspaced Short Palindromic Repeats
Hearing

A cross-sectional study of asymptomatic Plasmodium falciparum infection burden and risk factors in general population children in 12 villages in northern Uganda

Maziarz, M., Nabalende, H., Otim, I., Legason, I. D., Kinyera, T., Ogwang, M. D., Talisuna, A. O., Reynolds, S. J., Kerchan, P., Bhatia, K., Biggar, R. J., Goedert, J. J., Pfeiffer, R. M. & Mbulaiteye, S. M., Jun 20 2018, In : Malaria Journal. 17, 1, 240.

Research output: Contribution to journalArticle

Uganda
Falciparum Malaria
Plasmodium falciparum
Malaria
Cross-Sectional Studies
Vulnerable Populations
Naloxone
Substance-Related Disorders
Cross-Sectional Studies

Actigraphy-based sleep characteristics and aortic stiffness: the Multi-Ethnic Study of Atherosclerosis

Logan, J. G., Kang, H., Lobo, J. M., Sohn, M. W., Lin, G. M., Lima, J., Punjabi, N. M., Redline, S. & Kwon, Y., Jan 1 2018, (Accepted/In press) In : Journal of the American Society of Hypertension.

Research output: Contribution to journalArticle

Actigraphy
Vascular Stiffness
Atherosclerosis
Sleep
Pulse Wave Analysis

Actigraphy to evaluate sleep in the intensive care unit: A systematic review

Schwab, K. E., Ronish, B., Needham, D., To, A. Q., Martin, J. L. & Kamdar, B. B., Sep 1 2018, In : Annals of the American Thoracic Society. 15, 9, p. 1075-1082 8 p.

Research output: Contribution to journalReview article

Actigraphy
Intensive Care Units
Sleep
Critical Illness
Polysomnography

Action guide for addressing ethical challenges of resource allocation within community-based healthcare organizations

Harrison, K. L., Taylor, H. & Merritt, M., Jun 1 2018, In : Journal of Clinical Ethics. 29, 2, p. 124-138 15 p.

Research output: Contribution to journalArticle

Community Health Services
Resource Allocation
Decision Making
Organizations
decision making

Activation of AMPK by metformin improves withdrawal signs precipitated by nicotine withdrawal

Brynildsen, J. K., Lee, B. G., Perron, I. J., Jin, S., Kim, S. & Blendy, J. A., Apr 17 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 16, p. 4282-4287 6 p.

Research output: Contribution to journalArticle

AMP-Activated Protein Kinases
Metformin
Nicotine
Substance Withdrawal Syndrome
Smoking Cessation
Zucker Rats
Running
Eating
Body Weight
Neurons

Activation of Liver AMPK with PF-06409577 Corrects NAFLD and Lowers Cholesterol in Rodent and Primate Preclinical Models

Esquejo, R. M., Salatto, C. T., Delmore, J., Albuquerque, B., Reyes, A., Shi, Y., Moccia, R., Cokorinos, E., Peloquin, M., Monetti, M., Barricklow, J., Bollinger, E., Smith, B. K., Day, E. A., Nguyen, C., Geoghegan, K. F., Kreeger, J. M., Opsahl, A., Ward, J., Kalgutkar, A. S. & 8 othersTess, D., Butler, L., Shirai, N., Osborne, T., Steinberg, G. R., Birnbaum, M. J., Cameron, K. O. & Miller, R. A., May 1 2018, In : EBioMedicine. 31, p. 122-132 11 p.

Research output: Contribution to journalArticle

Enzyme Activators
Indoles
AMP-Activated Protein Kinases
Liver
Rats

Activation of Nrf2 in the liver is associated with stress resistance mediated by suppression of the growth hormone-regulated STAT5b transcription factor

Rooney, J., Oshida, K., Vasani, N., Vallanat, B., Ryan, N., Chorley, B. N., Wang, X., Bell, D. A., Wu, K. C., Aleksunes, L. M., Klaassen, C. D., Kensler, T. W. & Christopher Corton, J., Aug 1 2018, In : PloS one. 13, 8, e0200004.

Research output: Contribution to journalArticle

STAT5 Transcription Factor
Liver
stress tolerance
somatotropin
Growth Hormone

Activation of peroxisome proliferation–activated receptor-γ inhibits transforming growth factor-β1-induced airway smooth muscle cell proliferation by suppressing Smad–miR-21 signaling

Liu, L., Pan, Y., Zhai, C., Zhu, Y., Ke, R., Shi, W., Wang, J., Yan, X., Su, X., Song, Y., Gao, L. & Li, M., Jan 1 2018, (Accepted/In press) In : Journal of Cellular Physiology.

Research output: Contribution to journalArticle

Peroxisomes
Cell proliferation
Transforming Growth Factors
MicroRNAs
Smooth Muscle Myocytes

Active site alanine mutations convert deubiquitinases into high-affinity ubiquitin-binding proteins

Morrow, M. E., Morgan, M., Clerici, M., Growkova, K., Yan, M., Komander, D., Sixma, T. K., Simicek, M. & Wolberger, C., Jan 1 2018, (Accepted/In press) In : EMBO Reports.

Research output: Contribution to journalArticle

Ubiquitin
Alanine
Catalytic Domain
Carrier Proteins
Mutation

Active Surveillance of Small Renal Masses: A Safe Management Strategy for Select Patients

Gupta, M., Patel, H. D. & Pierorazio, P. M., Jan 1 2018, (Accepted/In press) In : European Urology.

Research output: Contribution to journalArticle

Kidney

Activities of dual combinations of antibiotics against multidrug-resistant nontuberculous mycobacteria recovered from patients with cystic fibrosis

Schwartz, M., Fisher, S., Story-Roller, E., Lamichhane, G. & Parrish, N. M., Oct 1 2018, In : Microbial Drug Resistance. 24, 8, p. 1191-1197 7 p.

Research output: Contribution to journalArticle

Nontuberculous Mycobacteria
Cystic Fibrosis
Anti-Bacterial Agents
Microbial Sensitivity Tests
Mycobacterium chelonae

Activity-Dependent Degradation of the Nascentome by the Neuronal Membrane Proteasome

Ramachandran, K. V., Fu, J. M., Schaffer, T. B., Na, C-H., Delannoy, M. & Margolis, S. S., Jul 5 2018, In : Molecular Cell. 71, 1, p. 169-177.e6

Research output: Contribution to journalArticle

Proteasome Endopeptidase Complex
Membranes
Ubiquitination
Proteins
Ribosomes

Activity of Aromathecins against African Trypanosomes

Nenortas, N. P., Cinelli, M. A., Morrell, A. E., Cushman, M. & Shapiro, T. A., Nov 1 2018, In : Antimicrobial agents and chemotherapy. 62, 11

Research output: Contribution to journalArticle

Trypanosomiasis
Poisoning
Topoisomerase Inhibitors
African Trypanosomiasis
Antiparasitic Agents

A Curriculum for Diagnostic Reasoning: JGIM’s Exercises in Clinical Reasoning

Subramanian, A., Connor, D. M., Berger, G., Lessing, J. N., Mehta, N., Manesh, R. & Kohlwes, J., Jan 1 2018, (Accepted/In press) In : Journal of general internal medicine.

Research output: Contribution to journalArticle

Curriculum

Acute appendicitis complicated by necrotizing fasciitis in a teenager

Kauffman, J. D., O'Brien, M., Snyder, C. W., Rottgers, S., Rideout, D. A. & Chandler, N. M., Oct 1 2018, In : Journal of Pediatric Surgery Case Reports. 37, p. 77-82 6 p.

Research output: Contribution to journalArticle

Necrotizing Fasciitis
Appendicitis
Abdominal Wall
Perineum
Operating Rooms

Acute bilateral superior branch vestibular neuropathy

Yacovino, D. A., Finlay, J. B., Jaimes, V. N. U., Verdecchia, D. H. & Schubert, M. C., May 17 2018, In : Frontiers in Neurology. 9, MAY, 353.

Research output: Contribution to journalArticle

Vestibular Neuronitis
Gait Ataxia
Vestibular Nerve
Saccule and Utricle
Semicircular Canals

Acute Cardiac Effects of Severe Pre-Eclampsia

Vaught, A., Kovell, L. C., Szymanski, L. M., Mayer, S. A., Seifert, S. M., Vaidya, D., Murphy, J., Argani, C. H., O'Kelly, A., York, S., Ouyang, P., Mukherjee, M. & Zakaria, S., Jul 3 2018, In : Journal of the American College of Cardiology. 72, 1, p. 1-11 11 p.

Research output: Contribution to journalArticle

Pre-Eclampsia
Pulmonary Edema
Peripartum Period
Blood Pressure
Ventricular Pressure

Acute Care Management of Stroke

Tippett, D., Feb 1 2018, In : Seminars in Speech and Language. 39, 1, p. 1-2 2 p.

Research output: Contribution to journalEditorial

Stroke

Acute Changes in Plasma Total Tau Levels Are Independent of Subconcussive Head Impacts in College Football Players

Kawata, K., Rubin, L., Wesley, L., Lee, J. H., Sim, T., Takahagi, M., Bellamy, A., Tierney, R. & Langford, D., Jan 15 2018, In : Journal of Neurotrauma. 35, 2, p. 260-266 7 p.

Research output: Contribution to journalArticle

Football
Head
tau Proteins
Mouth Protectors
Biomechanical Phenomena

Acute Enhancement of Cardiac Function by Phosphodiesterase Type 1 Inhibition

Hashimoto, T., Kim, G. E., Tunin, R. S., Adesiyun, T., Hsu, S., Nakagawa, R., Zhu, G., O'Brien, J. J., Hendrick, J. P., Davis, R. E., Yao, W., Beard, D., Hoxie, H. R., Wennogle, L. P., Lee, D. & Kass, D. A., Oct 30 2018, In : Circulation. 138, 18, p. 1974-1987 14 p.

Research output: Contribution to journalArticle

Receptors, Adrenergic, beta
Phosphoric Diester Hydrolases
Heart Failure
Dobutamine
Rabbits

Acute kidney injury after out of hospital pediatric cardiac arrest

Cornell, T. T., Selewski, D. T., Alten, J. A., Askenazi, D., Fitzgerald, J. C., Topjian, A., Holubkov, R., Page, K., Slomine, B. S., Christensen, J. R., Dean, J. M. & Moler, F. W., Oct 1 2018, In : Resuscitation. 131, p. 63-68 6 p.

Research output: Contribution to journalArticle

Out-of-Hospital Cardiac Arrest
Acute Kidney Injury
Induced Hypothermia
Heart Arrest
Lactates

Acute lysyl oxidase inhibition alters microvascular function in normotensive but not hypertensive men and women

Craighead, D. H., Wang, H., Santhanam, L. & Alexander, L. M., Mar 1 2018, In : American Journal of Physiology - Heart and Circulatory Physiology. 314, 3, p. H424-H433

Research output: Contribution to journalArticle

Protein-Lysine 6-Oxidase
Aminopropionitrile
Arterial Pressure
Vascular Stiffness
Vasoconstrictor Agents

Acute Pancreatitis: How Can MR Imaging Help

Porter, K. K., Cason, D. & Morgan, D. E., Aug 1 2018, In : Magnetic resonance imaging clinics of North America. 26, 3, p. 439-450 12 p.

Research output: Contribution to journalReview article

Pancreatitis
Pancreatic Ducts
Blood Vessels

Acute progressive paraplegia in heroin-associated myelopathy

Mahoney, K. W., Romba, M., Gailloud, P., Izbudak, I. & Saylor, D., Jan 1 2018, (Accepted/In press) In : Journal of Clinical Neuroscience.

Research output: Contribution to journalArticle

Spinal Cord Diseases
Paraplegia
Heroin
Leukocytosis
Heroin Dependence

Acute Systemic Complications of Convulsive Status Epilepticus-A Systematic Review

Sutter, R., Dittrich, T., Semmlack, S., Rüegg, S., Marsch, S. & Kaplan, P. W., Jan 1 2018, In : Critical Care Medicine. 46, 1, p. 138-145 8 p.

Research output: Contribution to journalArticle

Status Epilepticus
Takotsubo Cardiomyopathy
Respiratory Acidosis
Respiratory Muscles
Information Storage and Retrieval

Acute Type A Aortic Dissection in Pregnancy-Diagnostic and Therapeutic Challenges in a Multidisciplinary Setting

Patel, P. A., Fernando, R. J., MacKay, E. J., Yoon, J., Gutsche, J. T., Patel, S., Shah, R., Dashiell, J., Weiss, S. J., Goeddel, L., Evans, A. S., Feinman, J. W. & Augoustides, J. G., Jan 1 2018, (Accepted/In press) In : Journal of Cardiothoracic and Vascular Anesthesia.

Research output: Contribution to journalArticle

Fetal Viability
Pulsatile Flow
Postpartum Hemorrhage
Transesophageal Echocardiography
Cardiopulmonary Bypass

ACVR1C/SMAD2 signaling promotes invasion and growth in retinoblastoma

Asnaghi, L., White, D. T., Key, N., Choi, J., Mahale, A., Alkatan, H., Edward, D. P., Elkhamary, S. M., Al-Mesfer, S., Maktabi, A., Hurtado, C. G., Lee, G. Y., Carcaboso, A. M., Mumm, J., Safieh, L. A. & Eberhart, C. G., Jan 1 2018, (Accepted/In press) In : Oncogene.

Research output: Contribution to journalArticle

Retinoblastoma
Growth
Neoplasms
Small Interfering RNA
Zebrafish

Adamantinoma-like Ewing Sarcoma of the Salivary Glands: A Newly Recognized Mimicker of Basaloid Salivary Carcinomas

Rooper, L., Jo, V. Y., Antonescu, C. R., Nose, V., Westra, W. H., Seethala, R. R. & Bishop, J. A., Jan 1 2018, (Accepted/In press) In : American Journal of Surgical Pathology.

Research output: Contribution to journalArticle

Adamantinoma
Ewing's Sarcoma
Salivary Glands
Carcinoma
Synaptophysin