Find Research Outputs

2017

Activation mechanisms of the E3 ubiquitin ligase parkin

Panicker, N., Dawson, V. L. & Dawson, T. M. Sep 15 2017 In : Biochemical Journal. 474, 18, p. 3075-3086 12 p.

Research output: Research - peer-reviewReview article

Ubiquitin-Protein Ligases
Chemical activation
Parkinson Disease
Genes
Phosphotransferases

Activation of endoplasmic reticulum stress response by enhanced polyamine catabolism is important in the mediation of cisplatin-induced acute kidney injury

Zahedi, K., Barone, S., Destefano-Shields, C., Brooks, M., Murray-Stewart, T., Dunworth, M., Li, W., Doherty, J. R., Hall, M. A., Smith, R. D., Cleveland, J. L., Casero, R. A. & Soleimani, M. Sep 1 2017 In : PLoS ONE. 12, 9, e0184570

Research output: Research - peer-reviewArticle

cisplatin
polyamines
endoplasmic reticulum
stress response
kidneys

Activation of human basophils by A549 lung epithelial cells reveals a novel IgE-dependent response independent of allergen

Schroeder, J. T. & Bieneman, A. P. Aug 1 2017 In : Journal of Immunology. 199, 3, p. 855-865 11 p.

Research output: Research - peer-reviewArticle

Basophils
Allergens
Immunoglobulin E
Epithelial Cells
Lung

Activation of Langerhans cells promotes the inflammation in imiquimod-induced psoriasis-like dermatitis

Xiao, C., Zhu, Z., Sun, S., Gao, J., Fu, M., Liu, Y., Wang, G., Yao, X. & Li, W. Mar 1 2017 In : Journal of Dermatological Science. 85, 3, p. 170-177 8 p.

Research output: Research - peer-reviewArticle

imiquimod
Langerhans Cells
Dermatitis
Psoriasis
Inflammation

Activation of Nrf2 Signaling Augments Vesicular Stomatitis Virus Oncolysis via Autophagy-Driven Suppression of Antiviral Immunity

Olagnier, D., Lababidi, R. R., Hadj, S. B., Sze, A., Liu, Y., Naidu, S. D., Ferrari, M., Jiang, Y., Chiang, C., Beljanski, V., Goulet, M. L., Knatko, E. V., Dinkova-Kostova, A. T., Hiscott, J. & Lin, R. Aug 2 2017 In : Molecular Therapy. 25, 8, p. 1900-1916 17 p.

Research output: Research - peer-reviewArticle

Vesicular Stomatitis
Autophagy
Antiviral Agents
Immunity
Viruses

Activation of tumor suppressor LKB1 by honokiol abrogates cancer stem-like phenotype in breast cancer via inhibition of oncogenic Stat3

Sengupta, S. , Nagalingam, A. , Muniraj, N. , Bonner, M. Y. , Mistriotis, P. , Afthinos, A. , Kuppusamy, P. , Lanoue, D. , Cho, S. , Korangath, P. , Shriver, M. , Begum, A. , Merino, V. F. , Huang, C. Y. , Arbiser, J. L. , Matsui, W. , Györffy, B. , Konstantopoulos, K. , Sukumar, S. , Marignani, P. A. & 2 others Saxena, N. K. & Sharma, D. Oct 12 2017 In : Oncogene. 36, 41, p. 5709-5721 13 p.

Research output: Research - peer-reviewArticle

Phosphotransferases
Breast Neoplasms
Phenotype
Liver
Neoplasms

Active phantoms: A paradigm for ultrasound calibration using phantom feedback

Cheng, A., Guo, X., Zhang, H. K., Kang, H. J., Etienne-Cummings, R. & Boctor, E. M. Jul 1 2017 In : Journal of Medical Imaging. 4, 3, 035001

Research output: Research - peer-reviewArticle

Ultrasonics
Calibration
Feedback
Image quality
Experiments

Active Sensing: The Rat's Nose Dances in Step with Whiskers, Head, and Breath

Severson, K. S. & O'Connor, D. H. Mar 6 2017 In : Current Biology. 27, 5, p. R183-R185

Research output: Research - peer-reviewShort survey

Vibrissae
Touch
Nose
Head
touch (sensation)

Active Site Binding Is Not Sufficient for Reductive Deiodination by Iodotyrosine Deiodinase

Ingavat, N., Kavran, J. M., Sun, Z. & Rokita, S. E. Feb 28 2017 In : Biochemistry. 56, 8, p. 1130-1139 10 p.

Research output: Research - peer-reviewArticle

Iodide Peroxidase
Catalytic Domain
Enzymes
Binding Sites
2-iodophenol
Nephrectomy
Registries
Kidney
Chronic Renal Insufficiency
Survival

Active Surveillance Versus Watchful Waiting for Localized Prostate Cancer: A Model to Inform Decisions

Loeb, S., Zhou, Q., Siebert, U., Rochau, U., Jahn, B., Mühlberger, N., Carter, H. B., Lepor, H. & Braithwaite, R. S. 2017 (Accepted/In press) In : European Urology.

Research output: Research - peer-reviewArticle

Watchful Waiting
Prostatic Neoplasms
Quality of Life
Therapeutics
Quality-Adjusted Life Years

Active yeast ribosome preparation using monolithic anion exchange chromatography

Munoz, A. M., Yourik, P., Rajagopal, V., Nanda, J. S., Lorsch, J. R. & Walker, S. E. Feb 1 2017 In : RNA Biology. 14, 2, p. 188-196 9 p.

Research output: Research - peer-reviewArticle

Ribosomes
Anions
Chromatography
Yeasts
In Vitro Techniques

Activin receptor type 2A (ACVR2A) functions directly in osteoblasts as a negative regulator of bone mass

Goh, B. C., Singhal, V., Herrera, A. J., Tomlinson, R. E., Kim, S., Faugere, M. C., Germain-Lee, E. L., Clemens, T. L., Lee, S. J. & Digirolamo, D. J. 2017 In : Journal of Biological Chemistry. 292, 33, p. 13809-13822 14 p.

Research output: Research - peer-reviewArticle

Activin Receptors
Osteoblasts
Bone and Bones
Bone
Activins

Activity of sulfa drugs and their combinations against stationary phase b. Burgdorferi in vitro

Feng, J., Zhang, S., Shi, W. & Zhang, Y. Mar 22 2017 In : Antibiotics. 6, 1, 10

Research output: Research - peer-reviewReview article

Drug Combinations
Pharmaceutical Preparations
In Vitro Techniques
Dapsone
Anti-Bacterial Agents

Activity restriction recommendations and outcomes after reconstructive pelvic surgery: A randomized controlled trial

Mueller, M. G., Lewicky-Gaupp, C., Collins, S. A., Abernethy, M. G., Alverdy, A. & Kenton, K. 2017 In : Obstetrics and Gynecology. 129, 4, p. 608-614 7 p.

Research output: Research - peer-reviewArticle

Reconstructive Surgical Procedures
Randomized Controlled Trials
Prolapse
Pelvic Floor
Patient Satisfaction

Activity restriction recommendations and outcomes after reconstructive pelvic surgery: A randomized controlled trial

Mueller, M. G., Lewicky-Gaupp, C., Collins, S. A., Abernethy, M. G., Alverdy, A. & Kenton, K. 2017 In : Obstetrical and Gynecological Survey. 72, 7, p. 410-411 2 p.

Research output: Research - peer-reviewComment/debate

A cullin 4B-RING E3 ligase complex fine-tunes pancreatic δ cell paracrine interactions

Li, Q. , Cui, M. , Yang, F. , Li, N. , Jiang, B. , Yu, Z. , Zhang, D. , Wang, Y. , Zhu, X. , Hu, H. , Li, P. S. , Ning, S. L. , Wang, S. , Qi, H. , Song, H. , He, D. , Lin, A. , Zhang, J. , Liu, F. , Zhao, J. & 6 others Gao, L., Yi, F., Xue, T., Sun, J. P., Gong, Y. & Yu, X. Jun 30 2017 In : Journal of Clinical Investigation. 127, 7, p. 2631-2646 16 p.

Research output: Research - peer-reviewArticle

Cullin Proteins
Ubiquitin-Protein Ligases
Somatostatin-Secreting Cells
Somatostatin
Cell Communication

Acupuncture for the Treatment of Chronic Pain in the Military Population

Plunkett, A., Beltran, T., Haley, C., Kurihara, C., McCoart, A., Chen, L., Wilkinson, I. & Cohen, S. P. 2017 In : Clinical Journal of Pain. 33, 10, p. 939-943 5 p.

Research output: Research - peer-reviewArticle

Acupuncture Therapy
Chronic Pain
Population
Therapeutics
Acupuncture
Mucociliary Clearance
Propylene Glycol
Nicotine
Electronic Cigarettes
Tobacco Products
Street Drugs
Neuroimaging
Brain Injuries
Substance-Related Disorders
Young Adult

Acute Coronary Syndrome Screening and Diagnostic Practice Variation

Yiadom, M. Y. A. B. , Liu, X. , McWade, C. M. , Liu, D. , Storrow, A. B. , Herdon-Meadors, P. , Shuler, W. , Goldlust, E. , Sawyer, C. , Wong, A. , Tanski, M. , Patterson, B. , Wiener, D. , Baugh, C. W. , Carlson, J. N. , Strout, T. D. , Hill, C. D. , Turturro, M. , Whitcomb, C. , Dunlap, P. & 44 others McPheeters, R. A., Gavin, N., Hansen, J., Web, C., Calichman, M., Chen, P., Salazar, G., Shepard, B., Milligan, B., Rudd, K., Lee, A., Spiegel, T., Garvey, L., Rodi, S., Caterino, J., Furlong, B., Dubin, J., Imperato, J., Vohra, A., Mills, A., Hager, D., Podolsky, S., Novotny, A., Hartsfield, L., Bosco, S., McDermott, D. B., Pacella, C., Mazzeo, A., Guyette, M., McCoy, T., Gronczewski, C., Riordan, J., Leahy, J., Hocker, M., Mirarchi, F., Bhatia, M. C., Paul Cook, J., Ramanujan, V., Acquaye, J., Means, T., Strawn, C., Jackson, L., Davis, B. & and the ED Operations Study Group 2015 Jun 1 2017 In : Academic Emergency Medicine. 24, 6, p. 701-709 9 p.

Research output: Research - peer-reviewArticle

Acute Coronary Syndrome
Troponin
Hospital Emergency Service
Electrocardiography
Ischemia

Acute exacerbations and lung function loss in smokers with and without chronic obstructive pulmonary disease

Dransfield, M. T., Kunisaki, K. M., Strand, M. J., Anzueto, A., Bhatt, S. P., Bowler, R. P., Criner, G. J., Curtis, J. L., Hanania, N. A., Nath, H., Putcha, N., Roark, S. E., Wan, E. S., Washko, G. R., Wells, J. M., Wendt, C. H. & Make, B. J. Feb 1 2017 In : American Journal of Respiratory and Critical Care Medicine. 195, 3, p. 324-330 7 p.

Research output: Research - peer-reviewArticle

Chronic Obstructive Pulmonary Disease
Lung
Confidence Intervals
Emphysema
Health Care Costs
Olfactory Mucosa
Inflammation
Tumor Necrosis Factor-alpha
Neural Stem Cells
Tumor Necrosis Factor Receptors

Acute Kidney Injury, Risk Factors, and Prognosis in Hospitalized HIV-Infected Adults in South Africa, Compared by Tenofovir Exposure

Seedat, F., Martinson, N., Motlhaoleng, K., Abraham, P., Mancama, D., Naicker, S. & Variava, E. Jan 1 2017 In : AIDS Research and Human Retroviruses. 33, 1, p. 33-40 8 p.

Research output: Research - peer-reviewArticle

Tenofovir
South Africa
Acute Kidney Injury
HIV
Kidney

Acute myeloid leukemia, version 3.2017: Clinical practice guidelines in oncology

O'Donnell, M. R. , Tallman, M. S. , Abboud, C. N. , Altman, J. K. , Appelbaum, F. R. , Arber, D. A. , Bhatt, V. , Bixby, D. , Blum, W. , Coutre, S. E. , De Lima, M. , Fathi, A. T. , Fiorella, M. , Foran, J. M. , Gore, S. D. , Hall, A. C. , Kropf, P. , Lancet, J. , Maness, L. J. , Marcucci, G. & 14 others Martin, M. G., Moore, J. O., Olin, R., Peker, D., Pollyea, D. A., Pratz, K., Ravandi, F., Shami, P. J., Stone, R. M., Strickland, S. A., Wang, E. S., Wieduwilt, M., Gregory, K. & Ogba, N. Jul 1 2017 In : JNCCN Journal of the National Comprehensive Cancer Network. 15, 7, p. 926-957 32 p.

Research output: Research - peer-reviewReview article

Practice Guidelines
Acute Myeloid Leukemia
Leukemia
Guidelines
Therapeutics

Acute myeloid leukemia in the elderly: therapeutic options and choice

Webster, J. A. & Pratz, K. W. Jun 2 2017 (Accepted/In press) In : Leukemia and Lymphoma. p. 1-14 14 p.

Research output: Research - peer-reviewArticle

Acute Myeloid Leukemia
Therapeutics
Comorbidity
Age Groups
Transplants

Acute-onset chest pain in a 17-year-old female adolescent with systemic lupus erythematosus

Mangus, C. W., Fatusin, O. & Ngo, T. L. 2017 In : Pediatric Emergency Care. 33, 5, p. 346-349 4 p.

Research output: Research - peer-reviewArticle

Pericarditis
Chest Pain
Systemic Lupus Erythematosus
Pneumococcal Infections
Cardiac Tamponade

Acute Pain Characteristics in Patients with and without Chronic Pain following Lower Extremity Injury

Griffioen, M. A., Greenspan, J. D., Johantgen, M., Von Rueden, K., O'Toole, R. V., Dorsey, S. G. & Renn, C. L. Feb 1 2017 In : Pain Management Nursing. 18, 1, p. 33-41 9 p.

Research output: Research - peer-reviewArticle

Acute Pain
Chronic Pain
Lower Extremity
Pain
Wounds and Injuries

Acute pancreatitis patient registry to examine novel therapies in clinical experience (APPRENTICE): An international, multicenter consortium for the study of acute pancreatitis

Papachristou, G. I. , Machicado, J. D. , Stevens, T. , Goenka, M. K. , Ferreira, M. , Gutierrez, S. C. , Singh, V. K. , Kamal, A. , Gonzalez-Gonzalez, J. A. , Pelaez-Luna, M. , Gulla, A. , Zarnescu, N. O. , Triantafyllou, K. , Barbu, S. T. , Easler, J. , Ocampo, C. , Capurso, G. , Archibugi, L. , Cote, G. A. , Lambiase, L. & 13 others Kochhar, R., Chua, T., Tiwari, S. C., Nawaz, H., Park, W. G., De-Madaria, E., Lee, P. J., Wu, B. U., Greer, P. J., Dugum, M., Koutroumpakis, E., Akshintala, V. & Gougol, A. 2017 In : Annals of Gastroenterology. 30, 1, p. 106-113 8 p.

Research output: Research - peer-reviewArticle

Pancreatitis
Multicenter Studies
Registries
Therapeutics
Randomized Controlled Trials

Acute Retinal Necrosis: Presenting Characteristics and Clinical Outcomes in a Cohort of Polymerase Chain Reaction–Positive Patients

Butler, N. J., Moradi, A., Salek, S. S., Burkholder, B. M., Leung, T. G., Dunn, J. P. & Thorne, J. E. Jul 1 2017 In : American Journal of Ophthalmology. 179, p. 179-189 11 p.

Research output: Research - peer-reviewArticle

Acute Retinal Necrosis Syndrome
Polymerase Chain Reaction
Retinal Detachment
Confidence Intervals
Incidence

Adalimumab in the treatment of uveitis in juvenile idiopathic arthritis

Thorne, J. E. Apr 27 2017 In : New England Journal of Medicine. 376, 17, p. 1682-1683 2 p.

Research output: Research - peer-reviewShort survey

Adamantinoma
Ewing's Sarcoma
Parotid Gland
Differential Diagnosis
Epithelioid Cells

Adaptation of a Screening Tool for Perinatal Depression and Anxiety in Community-Based Maternal Health Services in Mali

Lasater, M. E., Beebe, M., Blomberg, K., Warren, N., Gresh, A., Hsih, K. & Winch, P. 2017 (Accepted/In press) In : Journal of Midwifery and Women's Health.

Research output: Research - peer-reviewArticle

Adaptation to TKI treatment reactivates ERK signaling in tyrosine kinase–driven leukemias and other malignancies

Bruner, J. K., Ma, H. S., Li, L., Qin, A. C. R., Rudek, M. A., Jones, R. J., Levis, M. J., Pratz, K. W., Pratilas, C. A. & Small, D. Oct 15 2017 In : Cancer Research. 77, 20, p. 5554-5563 10 p.

Research output: Research - peer-reviewArticle

Protein-Tyrosine Kinases
Leukemia
Neoplasms
Acute Myeloid Leukemia
Mitogen-Activated Protein Kinase Kinases

Adapting to the global shortage of cholera vaccines: Targeted single dose cholera vaccine in response to an outbreak in South Sudan

Parker, L. A., Rumunu, J., Jamet, C., Kenyi, Y., Lino, R. L., Wamala, J. F., Mpairwe, A. M., Ciglenecki, I., Luquero, F. J., Azman, A. S. & Cabrol, J. C. 2017 (Accepted/In press) In : The Lancet Infectious Diseases.

Research output: Research - peer-reviewArticle

Cholera Vaccines
Cholera
Disease Outbreaks
South Sudan
Immunization Programs

Adapting to the Rapid Evolution of Healthcare from a Shared Perspective

Yang, W. & Huang, J. 2017 (Accepted/In press) In : World Neurosurgery.

Research output: Research - peer-reviewArticle

Adaptive Enrichment Designs for Stroke Clinical Trials

Rosenblum, M. & Hanley, D. F. Jul 1 2017 In : Stroke. 48, 7, p. 2021-2025 5 p.

Research output: Research - peer-reviewReview article

Adaptive estimation of personalized maximum tolerated dose in cancer Phase i clinical trials based on all toxicities and individual genomic profile

Chen, Z., Li, Z., Zhuang, R., Yuan, Y., Kutner, M., Owonikoko, T., Curran, W. J. & Kowalski, J. Jan 1 2017 In : PLoS ONE. 12, 1, e0170187

Research output: Research - peer-reviewArticle

clinical trials
toxicity
genomics
neoplasms
dosage

Adaptive independent vector analysis for multi-subject complex-valued fMRI data

Kuang, L. D., Lin, Q. H., Gong, X. F., Cong, F. & Calhoun, V. D. Apr 1 2017 In : Journal of Neuroscience Methods. 281, p. 49-63 15 p.

Research output: Research - peer-reviewArticle

Magnetic Resonance Imaging
Normal Distribution
Noise

Adaptive resistance to anti-PD1 therapy by Tim-3 upregulation is mediated by the PI3K-Akt pathway in head and neck cancer

Shayan, G., Srivastava, R., Li, J., Schmitt, N., Kane, L. P. & Ferris, R. L. Jan 9 2017 (Accepted/In press) In : OncoImmunology.

Research output: Research - peer-reviewArticle

Inositol
Head and Neck Neoplasms
Phosphotransferases
Up-Regulation
Therapeutics

Adaptive responses of neuronal mitochondria to bioenergetic challenges: Roles in neuroplasticity and disease resistance

Raefsky, S. M. & Mattson, M. P. Jan 1 2017 In : Free Radical Biology and Medicine. 102, p. 203-216 14 p.

Research output: Research - peer-reviewReview article

Neuronal Plasticity
Disease Resistance
Energy Metabolism
Mitochondria
Brain

A Dataset and Benchmarks for Segmentation and Recognition of Gestures in Robotic Surgery

Ahmidi, N., Tao, L., Sefati, S., Gao, Y., Lea, C., Haro, B. B., Zappella, L., Khudanpur, S., Vidal, R. & Hager, G. D. Sep 1 2017 In : IEEE Transactions on Biomedical Engineering. 64, 9, p. 2025-2041 17 p., 7805258

Research output: Research - peer-reviewArticle

Hidden Markov models
Robotic surgery
Benchmarking
Time series
Dynamical systems

Addiction potential of cigarettes with reduced nicotine content in populations with psychiatric disorders and other vulnerabilities to tobacco addiction

Higgins, S. T., Heil, S. H., Sigmon, S. C., Tidey, J. W., Gaalema, D. E., Hughes, J. R., Stitzer, M. L., Durand, H., Bunn, J. Y., Priest, J. S., Arger, C. A., Miller, M. E., Bergeria, C. L., Davis, D. R., Streck, J. M., Reed, D. D., Skelly, J. M. & Tursi, L. Oct 1 2017 In : JAMA Psychiatry. 74, 10, p. 1056-1064 9 p.

Research output: Research - peer-reviewArticle

Nicotine
Tobacco Products
Tobacco
Psychiatry
Population

Additional considerations are required when preparing a protocol for a systematic review with multiple interventions

Chaimani, A., Caldwell, D. M., Li, T., Higgins, J. P. T. & Salanti, G. 2017 (Accepted/In press) In : Journal of Clinical Epidemiology.

Research output: Research - peer-reviewArticle

Network Meta-Analysis
Meta-Analysis

Additive effects of the Rho kinase inhibitor Y-27632 and vardenafil on relaxation of the corpus cavernosum tissue of patients with erectile dysfunction and clinical phosphodiesterase type 5 inhibitor failure

Uvin, P., Albersen, M., Bollen, I., Falter, M., Weyne, E., Linsen, L., Tinel, H., Sandner, P., Bivalacqua, T. J., De Ridder, D. J. M. K., Van der Aa, F., Brône, B. & Van Renterghem, K. Feb 1 2017 In : BJU International. 119, 2, p. 325-332 8 p.

Research output: Research - peer-reviewArticle

Phosphodiesterase 5 Inhibitors
rho-Associated Kinases
Erectile Dysfunction
Vardenafil Dihydrochloride
Y 27632

Addressing estimated hearing loss in adults in 2060

Goman, A. M., Reed, N. S. & Lin, F. R. Jul 1 2017 In : JAMA Otolaryngology - Head and Neck Surgery. 143, 7, p. 733-734 2 p.

Research output: Research - peer-reviewLetter

Coronary Vessels
Guidelines
Calcium
Cost-Benefit Analysis
Radiation

Addressing Parental Health in Pediatrics: Physician Perceptions of Relevance and Responsibility

Venkataramani, M., Cheng, T. L., Solomon, B. S. & Pollack, C. E. Sep 1 2017 In : Clinical Pediatrics. 56, 10, p. 953-958 6 p.

Research output: Research - peer-reviewArticle

Pediatrics
Physicians
Health
Child Health
Guideline Adherence

Addressing Technetium-99m Shortage

Mahesh, M. & Madsen, M. 2017 (Accepted/In press) In : Journal of the American College of Radiology.

Research output: Research - peer-reviewArticle