47-Year-old woman with six-week history of lower extremity weakness and eosinophilia

We present a case in which a 47-year-old woman had a six-week history of eosinophilia, bilateral weakness and paresthesias of the lower extremities, obstipation, and epigastric pain. Skin biopsies showed leukocytoclastic vasculitis, and a presumptive diagnosis of eosinophilic vasculitis was made. The patient's condition did not improve during a three-week course of high- dose corticosteroids. New weakness of the right hand, worsening weakness of the lower extremities, and bilateral numbness of the hands progressed rapidly. A massive intracranial hemorrhage occured unexpedtedly, and the patient died.