47-Year-old woman with six-week history of lower extremity weakness and eosinophilia

P. C. Lee, C. D. Gocke, E. D. Harris, M. E. Anderson, C. J. Bergin, J. M. Price, J. W. Lindsey

Research output: Contribution to journalArticlepeer-review


We present a case in which a 47-year-old woman had a six-week history of eosinophilia, bilateral weakness and paresthesias of the lower extremities, obstipation, and epigastric pain. Skin biopsies showed leukocytoclastic vasculitis, and a presumptive diagnosis of eosinophilic vasculitis was made. The patient's condition did not improve during a three-week course of high- dose corticosteroids. New weakness of the right hand, worsening weakness of the lower extremities, and bilateral numbness of the hands progressed rapidly. A massive intracranial hemorrhage occured unexpedtedly, and the patient died.

Original languageEnglish (US)
Pages (from-to)517-522
Number of pages6
JournalWestern Journal of Medicine
Issue number5
StatePublished - 1992
Externally publishedYes

ASJC Scopus subject areas

  • Medicine(all)


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