3H-1,2-dithiole-3-thione targets nuclear factor κB to block expression of inducible nitric-oxide synthase, prevents hypotension, and improves survival in endotoxemic rats

Medicine & Life Sciences

• 1,2-dithiol-3-thione 100%
• Nitric Oxide Synthase Type II 57%
• Hypotension 50%
• Thiones 37%
• Lipopolysaccharides 28%
• Septic Shock 22%
• Nitric Oxide 17%
• Inbred F344 Rats 12%
• Critical Care 9%
• Hepatocytes 9%
• Sepsis 8%
• Cause of Death 8%
• Perfusion 8%
• Chronic Disease 8%
• DNA 6%
• Enzymes 5%
• Liver 5%
• Animals 5%
• Serum 4%
• Pharmaceutical Preparations 4%
• Therapeutics 3%
• Neoplasms 3%