3D structural measurements of the proximal fFemur from 2D DXA images using a statistical atlas

Omar M. Ahmad, Krishna Ramamurthi, Kevin E. Wilson, Klaus Engelke, Mary Bouxsein, Russell H. Taylor

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

A method to obtain 3D structural measurements of the proximal femur from 2D DXA images and a statistical atlas is presented. A statistical atlas of a proximal femur was created consisting of both 3D shape and volumetric density information and then deformably registered to 2D fan-beam DXA images. After the registration process, a series of 3D structural measurements were taken on QCT-estimates generated by transforming the registered statistical atlas into a voxel volume. These measurements were compared to the equivalent measurements taken on the actual QCT (ground truth) associated with the DXA images for each of 20 human cadaveric femora. The methodology and results are presented to address the potential clinical feasibility of obtaining 3D structural measurements from limited angle DXA scans and a statistical atlas of the proximal femur in-vivo.

Original languageEnglish (US)
Title of host publicationMedical Imaging 2009
Subtitle of host publicationComputer-Aided Diagnosis
DOIs
StatePublished - Jun 15 2009
EventMedical Imaging 2009: Computer-Aided Diagnosis - Lake Buena Vista, FL, United States
Duration: Feb 10 2009Feb 12 2009

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume7260
ISSN (Print)1605-7422

Other

OtherMedical Imaging 2009: Computer-Aided Diagnosis
CountryUnited States
CityLake Buena Vista, FL
Period2/10/092/12/09

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Keywords

  • BMD
  • DXA
  • QCT
  • Statistical Atlas

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Atomic and Molecular Physics, and Optics
  • Radiology Nuclear Medicine and imaging

Cite this

Ahmad, O. M., Ramamurthi, K., Wilson, K. E., Engelke, K., Bouxsein, M., & Taylor, R. H. (2009). 3D structural measurements of the proximal fFemur from 2D DXA images using a statistical atlas. In Medical Imaging 2009: Computer-Aided Diagnosis [726005] (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 7260). https://doi.org/10.1117/12.811176