3D structural measurements of the proximal fFemur from 2D DXA images using a statistical atlas

Omar M. Ahmad, Krishna Ramamurthi, Kevin E. Wilson, Klaus Engelke, Mary Bouxsein, Russell H. Taylor

Research output: ResearchConference contribution

Abstract

A method to obtain 3D structural measurements of the proximal femur from 2D DXA images and a statistical atlas is presented. A statistical atlas of a proximal femur was created consisting of both 3D shape and volumetric density information and then deformably registered to 2D fan-beam DXA images. After the registration process, a series of 3D structural measurements were taken on QCT-estimates generated by transforming the registered statistical atlas into a voxel volume. These measurements were compared to the equivalent measurements taken on the actual QCT (ground truth) associated with the DXA images for each of 20 human cadaveric femora. The methodology and results are presented to address the potential clinical feasibility of obtaining 3D structural measurements from limited angle DXA scans and a statistical atlas of the proximal femur in-vivo.

LanguageEnglish (US)
Title of host publicationProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume7260
DOIs
StatePublished - 2009
EventMedical Imaging 2009: Computer-Aided Diagnosis - Lake Buena Vista, FL, United States
Duration: Feb 10 2009Feb 12 2009

Other

OtherMedical Imaging 2009: Computer-Aided Diagnosis
CountryUnited States
CityLake Buena Vista, FL
Period2/10/092/12/09

Fingerprint

Atlases
Femur
femur
Photon Absorptiometry
ground truth
fans
methodology
estimates
Fans

Keywords

  • BMD
  • DXA
  • QCT
  • Statistical Atlas

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics
  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Radiology Nuclear Medicine and imaging

Cite this

Ahmad, O. M., Ramamurthi, K., Wilson, K. E., Engelke, K., Bouxsein, M., & Taylor, R. H. (2009). 3D structural measurements of the proximal fFemur from 2D DXA images using a statistical atlas. In Progress in Biomedical Optics and Imaging - Proceedings of SPIE (Vol. 7260). [726005] DOI: 10.1117/12.811176

3D structural measurements of the proximal fFemur from 2D DXA images using a statistical atlas. / Ahmad, Omar M.; Ramamurthi, Krishna; Wilson, Kevin E.; Engelke, Klaus; Bouxsein, Mary; Taylor, Russell H.

Progress in Biomedical Optics and Imaging - Proceedings of SPIE. Vol. 7260 2009. 726005.

Research output: ResearchConference contribution

Ahmad, OM, Ramamurthi, K, Wilson, KE, Engelke, K, Bouxsein, M & Taylor, RH 2009, 3D structural measurements of the proximal fFemur from 2D DXA images using a statistical atlas. in Progress in Biomedical Optics and Imaging - Proceedings of SPIE. vol. 7260, 726005, Medical Imaging 2009: Computer-Aided Diagnosis, Lake Buena Vista, FL, United States, 2/10/09. DOI: 10.1117/12.811176
Ahmad OM, Ramamurthi K, Wilson KE, Engelke K, Bouxsein M, Taylor RH. 3D structural measurements of the proximal fFemur from 2D DXA images using a statistical atlas. In Progress in Biomedical Optics and Imaging - Proceedings of SPIE. Vol. 7260. 2009. 726005. Available from, DOI: 10.1117/12.811176
Ahmad, Omar M. ; Ramamurthi, Krishna ; Wilson, Kevin E. ; Engelke, Klaus ; Bouxsein, Mary ; Taylor, Russell H./ 3D structural measurements of the proximal fFemur from 2D DXA images using a statistical atlas. Progress in Biomedical Optics and Imaging - Proceedings of SPIE. Vol. 7260 2009.
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