3D registration of medical scanner volumes and tissue section photographs for evaluation of image-guided treatment

R. S. Lazebnik, D. L. Wilson, M. S. Breen, J. S. Lewin

Research output: Contribution to journalConference articlepeer-review

Abstract

We created a method for 3D registration of medical scanner image volumes to gross pathology images. We are applying it to evaluate interventional MRI thermal ablation and in vivo localized drug release from a new device, implanted using CT guidance. The method computes an optimum set of rigid body registration parameters by iterative minimization of the Euclidean distances between automatically generated correspondence points, along manually selected fiducial needle paths, and optional point landmarks. Voxel displacement errors depend only on needle localization error when the angle between needles was at least 15 degrees, and the distance objective function is a useful diagnostic for registration quality.

Original languageEnglish (US)
Pages (from-to)1007-1008
Number of pages2
JournalAnnual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
Volume2
StatePublished - Dec 1 2002
EventProceedings of the 2002 IEEE Engineering in Medicine and Biology 24th Annual Conference and the 2002 Fall Meeting of the Biomedical Engineering Society (BMES / EMBS) - Houston, TX, United States
Duration: Oct 23 2002Oct 26 2002

Keywords

  • Image guided therapy
  • Medical image processing
  • Volume registration

ASJC Scopus subject areas

  • Signal Processing
  • Biomedical Engineering
  • Computer Vision and Pattern Recognition
  • Health Informatics

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