3D magnetization-prepared true-FISP: A new technique for imaging coronary arteries

Vibhas S. Deshpande, Steven M. Shea, Gerhard Laub, Orlando P. Simonetti, J. Paul Finn, Debiao Li

Research output: Contribution to journalArticle

Abstract

The purpose of this work was to develop an ECG-triggered, segmented 3D true-FISP (fast imaging with steady-state precession) technique to improve the signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) of breath-hold coronary artery imaging. The major task was to optimize an appropriate magnetization preparation scheme to permit saturation of the epicardial fat signal. An α/2 preparation pulse was used to speed up the approach to steady-state following a frequency-selective fat-saturation pulse in each heartbeat. The application of dummy cycles was found to reduce the oscillation of the magnetization during data acquisition. The fat saturation and magnetization preparation scheme was validated with simulations and phantom studies. Volunteer studies demonstrated substantially increased SNR (55%) and CNR (178%) for coronary arteries compared to FLASH (fast low-angle shot) with the same imaging time. In conclusion, true-FISP is a promising technique for coronary artery imaging.

Original languageEnglish (US)
Pages (from-to)494-502
Number of pages9
JournalMagnetic resonance in medicine
Volume46
Issue number3
DOIs
StatePublished - 2001

Keywords

  • Coronary arteries
  • Fast imaging
  • MR angiography
  • Magnetic resonance imaging (MRI)

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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    Deshpande, V. S., Shea, S. M., Laub, G., Simonetti, O. P., Finn, J. P., & Li, D. (2001). 3D magnetization-prepared true-FISP: A new technique for imaging coronary arteries. Magnetic resonance in medicine, 46(3), 494-502. https://doi.org/10.1002/mrm.1219