3D coronary motion tracking in swine models with MR tracking catheters

Ehud J. Schmidt, Ryuichi Yoneyama, Charles L. Dumoulin, Robert D. Darrow, Eric Klein, Andrew J.M. Kiruluta, Motoya Hayase

Research output: Contribution to journalArticle

Abstract

Purpose: To develop MR-tracked catheters to delineate the three-dimensional motion of coronary arteries at high spatial and temporal resolution. Materials and Methods: Catheters with three tracking microcoils were placed into nine swine. During breath-holds, electrocardiographic (ECG)-synchronized 3D motion was measured at varying vessel depths. 3D motion was measured in American Heart Association left anterior descending (LAD) segments 6-7, left circumflex (LCX) segments 11-15, and right coronary artery (RCA) segments 2-3, at 60 -115 beats/min heart rates. Similar-length cardiac cycles were averaged. Intercoil cross-correlation identified early systolic phase (ES) and determined segment motion delay. Results: Translational and rotational motion, as a function of cardiac phase, is shown, with directionality and amplitude varying along the vessel length. Rotation (peak-to-peak solid-angle RCA ≈0.10, LAD ≈0.06, LCX ≈0.18 radian) occurs primarily during fast translational motion and increases distally. LCX displacement increases with heart rate by 18%. Phantom simulations of motion effects on high-resolution images, using RCA results, show artifacts due to translation and rotation. Conclusion: Magnetic resonance imaging (MRI) tracking catheters quantify motion at 20 fps and 1 mm3 resolution at multiple vessel depths, exceeding that available with other techniques. Imaging artifacts due to rotation are demonstrated. Motion-tracking catheters may provide physiological information during interventions and improve imaging spatial resolution.

Original languageEnglish (US)
Pages (from-to)86-98
Number of pages13
JournalJournal of Magnetic Resonance Imaging
Volume29
Issue number1
DOIs
StatePublished - Jan 1 2009
Externally publishedYes

Keywords

  • Coronary arteries
  • Intervention
  • MRI image artifacts
  • Motion

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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  • Cite this

    Schmidt, E. J., Yoneyama, R., Dumoulin, C. L., Darrow, R. D., Klein, E., Kiruluta, A. J. M., & Hayase, M. (2009). 3D coronary motion tracking in swine models with MR tracking catheters. Journal of Magnetic Resonance Imaging, 29(1), 86-98. https://doi.org/10.1002/jmri.21468