3′-methylphosphonate-modified oligo-2′-O-methylribonucleotides and their Tat peptide conjugates: Uptake and stability in mouse fibroblasts in culture

Engineering & Materials Science

• Oligonucleotides 81%
• Fibroblasts 80%
• Peptides 72%
• Cell culture 70%
• Cells 17%
• Derivatives 14%
• Fluorescence microscopy 13%
• Oligomers 13%
• Degradation 12%
• Lipids 12%
• Polyacrylates 12%
• Electrophoresis 11%
• Mass spectrometry 11%
• Hydrolysis 11%
• Gels 9%
• Glass 7%
• Plastics 6%

Medicine & Life Sciences

• methylphosphonic acid 100%
• Oligonucleotides 57%
• Fibroblasts 40%
• Peptides 35%
• Fluorescein 19%
• spleen exonuclease 15%
• Disulfides 9%
• Cell Nucleus 9%
• Fluorescence Microscopy 9%
• Glass 8%
• Plastics 8%
• Polyacrylamide Gel Electrophoresis 8%
• Hydrolysis 8%
• Mass Spectrometry 8%
• Cell Culture Techniques 6%
• Lipids 6%
• Serum 4%
• 4-(2-aminooxyethoxy)-2-(ethylureido)quinoline 1%

Chemical Compounds

• Oligonucleotide 48%
• Polyacrylamide Gel Electrophoresis 9%
• Fluorescence Microscopy 9%
• Disulfide 7%
• Oligomer 7%
• Kd 6%
• Glass 6%
• Mass Spectrometry 6%
• Hydrolysis 5%