TY - JOUR
T1 - 2,5-dimethoxy-4-methyl-amphetamine (STP)
T2 - A new hallucinogenic drug
AU - Snyder, Solomon H.
AU - Faillace, Louis
AU - Hollister, Leo
PY - 1967
Y1 - 1967
N2 - We have assessed the effects in normal control volunteers of 2,5dimethoxy-4-methyl-amphetamine, the chemical present in the hallucinogenic drug STP, in two independent trials. In low doses, this compound produces a mild euphoria. Doses greater than 3 milligrams may cause pronounced hallucinogenic effects lasting about 8 hours and similar to those produced by hallucinogenic doses of lysergic acid diethylamide, mescaline, and psilocybin. 2,5-Dimethoxy4-methyl-amphetamine, which is chemically related to mescaline and amphetamine, is about 100 times more potent as a hallucinogen than mescaline and only one-thirtieth as potent as lysergic acid diethylamide. Its psychological effects are not accentuated by chlorpromazine.
AB - We have assessed the effects in normal control volunteers of 2,5dimethoxy-4-methyl-amphetamine, the chemical present in the hallucinogenic drug STP, in two independent trials. In low doses, this compound produces a mild euphoria. Doses greater than 3 milligrams may cause pronounced hallucinogenic effects lasting about 8 hours and similar to those produced by hallucinogenic doses of lysergic acid diethylamide, mescaline, and psilocybin. 2,5-Dimethoxy4-methyl-amphetamine, which is chemically related to mescaline and amphetamine, is about 100 times more potent as a hallucinogen than mescaline and only one-thirtieth as potent as lysergic acid diethylamide. Its psychological effects are not accentuated by chlorpromazine.
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U2 - 10.1126/science.158.3801.669
DO - 10.1126/science.158.3801.669
M3 - Article
C2 - 4860952
AN - SCOPUS:0014191923
SN - 0036-8075
SP - 669
EP - 670
JO - Science
JF - Science
ER -