20S ways to apoptosis

David J. McConkey

doi:10.1038/nchembio0908-528

20S ways to apoptosis

David J. McConkey

Research output: Contribution to journal › Short survey › peer-review

2 Scopus citations

Abstract

Chemical inhibitors of the proteasome have received substantial attention owing to the success of bortezomib in the treatment of multiple myeloma. A recent whole-cell screen identified the proteasome inhibitor argyrin A and suggests a new role for p27^Kip-1 in regulating apoptosis.

Original language	English (US)
Pages (from-to)	528-529
Number of pages	2
Journal	Nature chemical biology
Volume	4
Issue number	9
DOIs	https://doi.org/10.1038/nchembio0908-528
State	Published - Sep 2008
Externally published	Yes

ASJC Scopus subject areas

Molecular Biology
Cell Biology

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title = "20S ways to apoptosis",

abstract = "Chemical inhibitors of the proteasome have received substantial attention owing to the success of bortezomib in the treatment of multiple myeloma. A recent whole-cell screen identified the proteasome inhibitor argyrin A and suggests a new role for p27Kip-1 in regulating apoptosis.",

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year = "2008",

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AB - Chemical inhibitors of the proteasome have received substantial attention owing to the success of bortezomib in the treatment of multiple myeloma. A recent whole-cell screen identified the proteasome inhibitor argyrin A and suggests a new role for p27Kip-1 in regulating apoptosis.

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DO - 10.1038/nchembio0908-528

M3 - Short survey

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JO - Nature chemical biology

JF - Nature chemical biology

IS - 9

ER -

20S ways to apoptosis

Abstract

ASJC Scopus subject areas

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