20S ways to apoptosis

Research output: Contribution to journalShort survey

Abstract

Chemical inhibitors of the proteasome have received substantial attention owing to the success of bortezomib in the treatment of multiple myeloma. A recent whole-cell screen identified the proteasome inhibitor argyrin A and suggests a new role for p27Kip-1 in regulating apoptosis.

Original languageEnglish (US)
Pages (from-to)528-529
Number of pages2
JournalNature chemical biology
Volume4
Issue number9
DOIs
StatePublished - Sep 2008
Externally publishedYes

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ASJC Scopus subject areas

  • Molecular Biology
  • Cell Biology

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