2006 Bethesda international consensus recommendations on the flow cytometric immunophenotypic analysis of hematolymphoid neoplasia: Medical indications

Bruce H. Davis, J. T. Holden, M. C. Bene, M. J. Borowitz, R. C. Braylan, D. Cornfield, W. Gorczyca, R. Lee, R. Maiese, A. Orfao, D. Wells, B. L. Wood, M. Stetler-Stevenson

Research output: Contribution to journalArticle

Abstract

The clinical indications for diagnostic flow cytometry studies are an evolving consensus, as the knowledge of antigenic definition of hematolymphoid malignancies and the prognostic significance of antigen expression evolves. Additionally the standard of care is not routinely communicated to practicing clinicians and diagnostic services, especially as may relate to new technologies. Accordingly there is often uncertainty on the part of clinicians, payers of medical services, diagnostic physicians and scientists as to the appropriate use of diagnostic flow cytometry. In an attempt to communicate contemporary diagnostic utility of immunophenotypic flow cytometry in the diagnosis and follow-up of patients with hematolymphoid malignancies, the Clinical Cytometry Society organized a two day meeting of international experts in this area to reach a consensus as to this diagnostic tool. This report summarizes the appropriate use of diagnostic flow cytometry as determined by unanimous approval of these experienced practitioners.

Original languageEnglish (US)
Pages (from-to)S5-S13
JournalCytometry Part B - Clinical Cytometry
Volume72
Issue numberSUPPL. 1
DOIs
StatePublished - 2007

Keywords

  • Leukemia diagnosis
  • Lymphoma diagnosis
  • Lymphoproliferative disorder
  • Multiple myeloma
  • Myelodysplasia

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Histology
  • Cell Biology

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    Davis, B. H., Holden, J. T., Bene, M. C., Borowitz, M. J., Braylan, R. C., Cornfield, D., Gorczyca, W., Lee, R., Maiese, R., Orfao, A., Wells, D., Wood, B. L., & Stetler-Stevenson, M. (2007). 2006 Bethesda international consensus recommendations on the flow cytometric immunophenotypic analysis of hematolymphoid neoplasia: Medical indications. Cytometry Part B - Clinical Cytometry, 72(SUPPL. 1), S5-S13. https://doi.org/10.1002/cyto.b.20365