193 nm excimer laser-induced fluorescence spectroscopy during corneal ablative surgery

Roy S. Chuck, David Cohen, Peter J McDonnell, Warren S. Grundfest

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

The evolution of real-time laser-induced fluorescence at progressive corneal depths detected during excimer laser corneal ablative surgery at 193 nm excitation was investigated using an 8.5 mm corneal button trephined from a fresh frozen cadaveric human globe, and placed in the ablative 192 nm excimer laser beam path. The spectra of the initial epithelial ablation - consecutive spectra taken in the anterior to mid-stroma after lamellar keratomileusis and subsequent laser ablation, and the initial spectrum taken while ablating from the endothelial side was demonstrated. A striking progression of the spectra was observed as ablation progresses from the epithelial side towards the endothelial side.

Original languageEnglish (US)
Title of host publicationConference Proceedings - Lasers and Electro-Optics Society Annual Meeting-LEOS
PublisherIEEE
Pages218-219
Number of pages2
Volume1
StatePublished - 1999
Externally publishedYes
EventProceedings of the 1999 12th Annual Meeting IEEE Lasers and Electro-Optics Society (LEOS'99) - San Francisco, CA, USA
Duration: Nov 8 1999Nov 11 1999

Other

OtherProceedings of the 1999 12th Annual Meeting IEEE Lasers and Electro-Optics Society (LEOS'99)
CitySan Francisco, CA, USA
Period11/8/9911/11/99

Fingerprint

Fluorescence spectroscopy
Excimer lasers
Ablation
Surgery
Laser ablation
Laser beams
Fluorescence
Lasers

ASJC Scopus subject areas

  • Control and Systems Engineering
  • Electrical and Electronic Engineering
  • Industrial and Manufacturing Engineering

Cite this

Chuck, R. S., Cohen, D., McDonnell, P. J., & Grundfest, W. S. (1999). 193 nm excimer laser-induced fluorescence spectroscopy during corneal ablative surgery. In Conference Proceedings - Lasers and Electro-Optics Society Annual Meeting-LEOS (Vol. 1, pp. 218-219). IEEE.

193 nm excimer laser-induced fluorescence spectroscopy during corneal ablative surgery. / Chuck, Roy S.; Cohen, David; McDonnell, Peter J; Grundfest, Warren S.

Conference Proceedings - Lasers and Electro-Optics Society Annual Meeting-LEOS. Vol. 1 IEEE, 1999. p. 218-219.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Chuck, RS, Cohen, D, McDonnell, PJ & Grundfest, WS 1999, 193 nm excimer laser-induced fluorescence spectroscopy during corneal ablative surgery. in Conference Proceedings - Lasers and Electro-Optics Society Annual Meeting-LEOS. vol. 1, IEEE, pp. 218-219, Proceedings of the 1999 12th Annual Meeting IEEE Lasers and Electro-Optics Society (LEOS'99), San Francisco, CA, USA, 11/8/99.
Chuck RS, Cohen D, McDonnell PJ, Grundfest WS. 193 nm excimer laser-induced fluorescence spectroscopy during corneal ablative surgery. In Conference Proceedings - Lasers and Electro-Optics Society Annual Meeting-LEOS. Vol. 1. IEEE. 1999. p. 218-219
Chuck, Roy S. ; Cohen, David ; McDonnell, Peter J ; Grundfest, Warren S. / 193 nm excimer laser-induced fluorescence spectroscopy during corneal ablative surgery. Conference Proceedings - Lasers and Electro-Optics Society Annual Meeting-LEOS. Vol. 1 IEEE, 1999. pp. 218-219
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