β-human chorionic gonadotropin as a monitor of pregnancy outcome in in vitro fertilization - Embryo transfer patients

Liu Hung-Ching Liu, D. Kreiner, S. J. Muasher, G. Jones, H. Jones, Z. Rosenwaks

Research output: Contribution to journalArticle

Abstract

Serum human chorionic gonadotropin (hCG) was studied to test its predictability of pregnancy outcome in in vitro fertilization (IVF) patients. The mean ± standard deviation of serum hCG concentration related to the day complete clearance of exogenous hCG was derived from 47 single term pregnancies as a normal range. This range can be used to predict spontaneous abortion (77%), multiple pregnancy (60%), and abortion in multiple-sac pregnancies terminating in the birth of fewer infants than the initial number of sacs (80%). The results also showed that our stimulation protocol did not affect the clearance rate and doubling time of endogenous hCG or implantation time as suggested by the time of endogenous hCG detection and that spontaneous abortion may be due to late implantation.

Original languageEnglish (US)
Pages (from-to)89-94
Number of pages6
JournalFertility and sterility
Volume50
Issue number1
DOIs
StatePublished - 1988

ASJC Scopus subject areas

  • Reproductive Medicine
  • Obstetrics and Gynecology

Fingerprint Dive into the research topics of 'β-human chorionic gonadotropin as a monitor of pregnancy outcome in in vitro fertilization - Embryo transfer patients'. Together they form a unique fingerprint.

  • Cite this