α4 integrin is expressed in a subset of cranial neural crest cells and in epicardial progenitor cells during early mouse development

Karen A. Pinco, Stephen Liu, Joy T. Yang

Research output: Contribution to journalArticle

Abstract

By RNA in situ hybridization and immunohistochemical analyses of early stage mouse embryos, we find that α4 integrin gene is expressed in migratory cranial neural crest cells originating from the presumptive forebrain, midbrain, and rhombomeres 1 and 2 of the presumptive hindbrain. α4 is also expressed in epicardial progenitor cells in the septum transversum that migrate to the heart. (C) 2001 Elsevier Science Ireland Ltd.

Original languageEnglish (US)
Pages (from-to)99-103
Number of pages5
JournalMechanisms of Development
Volume100
Issue number1
DOIs
StatePublished - 2001

Keywords

  • α4 integrins
  • Cell adhesion
  • Epicardium
  • Heart
  • Migration
  • Mouse development
  • Neural crest
  • Otic vesicle

ASJC Scopus subject areas

  • Developmental Biology
  • Developmental Neuroscience

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